J. Sancho

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SIMPLE estimate of the free energy change due to aliphatic mutations: Superior predictions based on first principles

C. Camacho, M. Bueno, J. Sancho, 2007, Proteins.

A. Fersht, J. Sancho, A. Kippen, 1994, Biochemistry.

Native hydrogen bonds in a molten globule: the apoflavodoxin thermal intermediate.

J. Sancho, M. P. Irún, M. M. Garcia-Mira, 2001, Journal of molecular biology.

Alpha-helix stability in proteins. I. Empirical correlations concerning substitution of side-chains at the N and C-caps and the replacement of alanine by glycine or serine at solvent-exposed surfaces.

L Serrano, A. Fersht, L. Serrano, 1992, Journal of molecular biology.

Histidine-aromatic interactions in barnase. Elevation of histidine pKa and contribution to protein stability.

A. Fersht, J. Sancho, R. Loewenthal, 1992, Journal of molecular biology.

Predicting stabilizing mutations in proteins using Poisson-Boltzmann based models: study of unfolded state ensemble models and development of a successful binary classifier based on residue interaction energies.

P. Echenique, J. Sancho, Jorge Estrada, 2015, Physical chemistry chemical physics : PCCP.

Discovering putative prion sequences in complete proteomes using probabilistic representations of Q/N-rich domains

Salvador Ventura, Javier Sancho, J. Sancho, 2013, BMC Genomics.

The mechanism of water/ion exchange at a protein surface: a weakly bound chloride in Helicobacter pylori apoflavodoxin.

J. Sancho, M. Morón, J. J. Galano-Frutos, 2015, Physical chemistry chemical physics : PCCP.

Determination of the excited-state lifetimes of the tryptophan residues in barnase, via multifrequency phase fluorometry of tryptophan mutants.

A. Fersht, M. Froeyen, J. Sancho, 1992, Biochemistry.

Distant and New Mutations in CTX-M-1 β-Lactamase Affect Cefotaxime Hydrolysis

O. Abián, M. Galleni, J. Sancho, 2011, Antimicrobial Agents and Chemotherapy.

Structure of stable protein folding intermediates by equilibrium phi-analysis: the apoflavodoxin thermal intermediate.

Marta Bueno, María Angeles Jiménez, Javier Sancho, 2004, Journal of molecular biology.

The Tryptophan/Histidine interaction in α-helices

Juan Fernández-Recio, Javier Sancho, Paz Sevilla, 1997 .

Comparison of DNA binding across protein superfamilies

Bruno Contreras-Moreira, Vladimir Espinosa Angarica, Javier Sancho, 2010, Proteins.

Mechanism of Low Density Lipoprotein (LDL) Release in the Endosome

A. Velázquez‐Campoy, J. Sancho, M. Pocovi, 2008, Journal of Biological Chemistry.

Structural analysis of an equilibrium folding intermediate in the apoflavodoxin native ensemble by small-angle X-ray scattering.

Modesto Orozco, Pau Bernadó, Javier Sancho, 2011, Journal of molecular biology.

Exploring the complete mutational space of the LDL receptor LA5 domain using molecular dynamics: linking SNPs with disease phenotypes in familial hypercholesterolemia

M. Orozco, J. Sancho, V. Angarica, 2016, Human molecular genetics.

Therapeutic strategies for Gaucher disease: miglustat (NB-DNJ) as a pharmacological chaperone for glucocerebrosidase and the different thermostability of velaglucerase alfa and imiglucerase.

O. Abián, A. Velázquez‐Campoy, J. Sancho, 2011, Molecular pharmaceutics.

High-Throughput Screening Methodology to Identify Alpha-Synuclein Aggregation Inhibitors

J. Sancho, S. Ventura, Jordi Pujols, 2017, International journal of molecular sciences.

Alchemical Design of Pharmacological Chaperones with Higher Affinity for Phenylalanine Hydroxylase

Bruno L. Victor, A. Velázquez‐Campoy, J. Sancho, 2022, International journal of molecular sciences.

Energetics of aliphatic deletions in protein cores

Marta Bueno, Jorge Estrada, Javier Sancho, 2006, Protein science : a publication of the Protein Society.

How FMN Binds to Anabaena Apoflavodoxin

J. Sancho, M. P. Irún, A. Romero, 2003, Journal of Biological Chemistry.

The Long and Short Flavodoxins

M. Bueno, J. Sancho, M. Lillo, 2004, Journal of Biological Chemistry.

Anabaena apoflavodoxin hydrogen exchange: on the stable exchange core of the alpha/beta(21345) flavodoxin-like family.

J. Sancho, M. Jiménez, M. Rico, 2001, Proteins.

Protein Dynamics Governed by Interfaces of High Polarity and Low Packing Density

J. Sancho, V. Angarica, V. E. Angarica, 2012, PloS one.

Small Molecule Inhibitors of the Response Regulator ArsR Exhibit Bactericidal Activity against Helicobacter pylori

A. Velázquez‐Campoy, Á. Lanas, J. Sancho, 2020, Microorganisms.

The stability of 2-state, 3-state and more-state proteins from simple spectroscopic techniques... plus the structure of the equilibrium intermediates at the same time.

J. Sancho, 2013, Archives of biochemistry and biophysics.

New variant (Val597Ile) in transmembrane region of the TSH receptor with human chorionic gonadotropin hypersensitivity in familial gestational hyperthyroidism.

J. Sancho, P. Caron, F. Savagner, 2020, Clinical endocrinology.

PrionScan: an online database of predicted prion domains in complete proteomes

J. Sancho, S. Ventura, Vladimir Espinosa Angarica, 2014, BMC Genomics.

Structural and Mechanistic Basis of the Interaction between a Pharmacological Chaperone and Human Phenylalanine Hydroxylase

J. Sancho, R. Hurtado-Guerrero, E. Lira-Navarrete, 2012, Chembiochem : a European journal of chemical biology.

Protein haploinsufficiency drivers identify MYBPC3 mutations that cause hypertrophic cardiomyopathy

L. Monserrat, J. Sancho, L. Serrano, 2020, medRxiv.

Insights into immune evasion of human metapneumovirus: novel 180- and 111-nucleotide duplications within viral G gene throughout 2014-2017 seasons in Barcelona, Spain

T. Pumarola, J. Sancho, A. Antón, 2020, Journal of Clinical Virology.

Protposer: The web server that readily proposes protein stabilizing mutations with high PPV

J. Sancho, H. García-Cebollada, Alfonso López, 2022, Computational and structural biotechnology journal.

Allosteric Inhibitors of the NS 3 Protease from the Hepatitis C Virus

O. Abián, A. Velázquez‐Campoy, S. Vega, 2013 .

Allosteric Inhibitors of the NS3 Protease from the Hepatitis C Virus

O. Abián, A. Velázquez‐Campoy, S. Vega, 2013, PloS one.

Protein-cation interactions: structural and thermodynamic aspects.

O. Abián, A. Velázquez‐Campoy, S. Vega, 2011, Current protein & peptide science.

The closed conformation of the LDL receptor is destabilized by the low Ca++ concentration but favored by the high Mg++ concentration in the endosome

J. Carrodeguas, J. Sancho, A. Marina, 2016, FEBS letters.

The closed conformation of the LDL receptor is destabilized by the low Ca++ concentration but favored by the high Mg++ concentration in the endosome

J. Carrodeguas, J. Sancho, A. Marina, 2015, FEBS letters.

Rational stabilization of complex proteins: a divide and combine approach

A. Velázquez‐Campoy, M. Bueno, J. Sancho, 2015, Scientific Reports.

Flavodoxin:Quinone Reductase (FqrB): a Redox Partner of Pyruvate:Ferredoxin Oxidoreductase That Reversibly Couples Pyruvate Oxidation to NADPH Production in Helicobacter pylori and Campylobacter jejuni

J. Sancho, Matthew A. Croxen, N. Cremades, 2007, Journal of bacteriology.

Rescue of misfolded proteins and stabilization by small molecules.

R. Stevens, Aurora Martínez, J. Sancho, 2010, Methods in molecular biology.

DMSO affects Aβ1–40's conformation and interactions with aggregation inhibitors as revealed by NMR

D. Laurents, J. Carrodeguas, D. Pantoja-Uceda, 2015 .

What Works (and What Doesn't) in Estimating the Change in Free Energy due to Point Mutations in the Protein Interior

Marta Bueno, Javier Sancho, Carlos J. Camacho, 2004, Spanish Bioinformatics Conference.

An intragenic suppressor in the cytochrome c oxidase I gene of mouse mitochondrial DNA.

M. Bueno, J. Sancho, J. Enríquez, 2003, Human molecular genetics.

A look at the face of the molten globule: Structural model of the Helicobacter pylori apoflavodoxin ensemble at acidic pH

J. Sancho, J. J. Galano-Frutos, R. Torreblanca, 2022, Protein science : a publication of the Protein Society.

Preparation and properties of a cross-linked complex between ferredoxin--NADP+ reductase and flavodoxin.

J. Sancho, D. Edmondson, J. Pueyo, 1989, European journal of biochemistry.

Design, synthesis and structure-activity evaluation of novel 2-pyridone-based inhibitors of α-synuclein aggregation with potentially improved BBB permeability.

J. Sancho, S. Ventura, I. Pallarès, 2021, Bioorganic chemistry.

Stereoselective synthesis and biological evaluation as inhibitors of hepatitis C virus RNA polymerase of GSK3082 analogues with structural diversity at the 5-position.

O. Abián, A. Velázquez‐Campoy, J. Sancho, 2019, European journal of medicinal chemistry.

Miglustat (NB-DNJ) works as a chaperone for mutated acid beta-glucosidase in cells transfected with several Gaucher disease mutations.

J. Sancho, Jorge Estrada, S. Pampín, 2005, Blood cells, molecules & diseases.

Discovery of novel inhibitors of amyloid β-peptide 1-42 aggregation.

J. Carrodeguas, M. Maddelein, J. Sancho, 2012, Journal of medicinal chemistry.

Electron-nuclear double resonance and hyperfine sublevel correlation spectroscopic studies of flavodoxin mutants from Anabaena sp. PCC 7119.

J. Sancho, M. Medina, R. Cammack, 1999, Biophysical journal.

ProtSA: a web application for calculating sequence specific protein solvent accessibilities in the unfolded ensemble

Javier Sancho, Pau Bernadó, Martin Blackledge, 2009, BMC Bioinformatics.

Sequence-specific solvent accessibilities of protein residues in unfolded protein ensembles.

Pau Bernadó, Martin Blackledge, Javier Sancho, 2006, Biophysical journal.

Towards a new therapeutic target: Helicobacter pylori flavodoxin.

M. Bueno, J. Sancho, M. Toja, 2005, Biophysical chemistry.

A comparative study of the thermal stability of plastocyanin, cytochrome c6 and Photosystem I in thermophilic and mesophilic cyanobacteria

J. Sancho, M. A. De la Rosa, L. A. Campos, 2004, Photosynthesis Research.

The active site of pepsin is formed in the intermediate conformation dominant at mildly acidic pH

Luis Alberto Campos, Javier Sancho, J. Sancho, 2003, FEBS letters.

Circular dichroism studies of barnase and its mutants: characterization of the contribution of aromatic side chains.

A. Fersht, S. Vuilleumier, J. Sancho, 1993, Biochemistry.

Interaction of ferredoxin-NADP+ reductase from Anabaena with its substrates.

J. Sancho, C. Gómez-Moreno, C. Gomez-moreno, 1991, Archives of biochemistry and biophysics.

Arginyl groups involved in the binding of Anabaena ferredoxin--NADP+ reductase to NADP+ and to ferredoxin.

J. Sancho, M. Medina, C. Gómez-Moreno, 1990, European journal of biochemistry.

Purification and properties of ferredoxin-NADP+ oxidoreductase from the nitrogen-fixing cyanobacteria Anabaena variabilis.

J. Sancho, M. Peleato, D. Edmondson, 1988, Archives of biochemistry and biophysics.

Identification of pharmacological chaperones as potential therapeutic agents to treat phenylketonuria.

A. Velázquez‐Campoy, Aurora Martínez, J. Sancho, 2008, The Journal of clinical investigation.

Dissecting the Energetics of the Apoflavodoxin-FMN Complex*

J. Sancho, A. Romero, A. Lostao, 2000, The Journal of Biological Chemistry.

The FurA regulon in Anabaena sp. PCC 7120: in silico prediction and experimental validation of novel target genes

J. Sancho, M. Fillat, V. E. Angarica, 2014, Nucleic acids research.

Molecular dynamics simulations for genetic interpretation in protein coding regions: where we are, where to go and when

Javier Sancho, Juan J Galano-Frutos, Helena García-Cebollada, 2019, Briefings Bioinform..

Thermal stability of beta-lactoglobulin in the presence of aqueous solution of alcohols and polyols.

J. Sancho, J. Lozano, C. M. Romero, 2007, International journal of biological macromolecules.

Protein haploinsufficiency drivers identify MYBPC3 variants that cause hypertrophic cardiomyopathy

L. Monserrat, J. Sancho, L. Serrano, 2021, The Journal of biological chemistry.

LDL receptor/lipoprotein recognition: endosomal weakening of ApoB and ApoE binding to the convex face of the LR5 repeat

A. Velázquez‐Campoy, J. Sancho, O. Millet, 2014, The FEBS journal.

Underexposed polar residues and protein stabilization.

Javier Sancho, Sara Ayuso-Tejedor, O. Abián, 2011, Protein engineering, design & selection : PEDS.

Effect of alanine versus glycine in α-helices on protein stability

A. Fersht, L. Serrano, J. Sancho, 1992, Nature.

Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons

Salvador Ventura, Susanna Navarro, Ernest Giralt, 2018, Proceedings of the National Academy of Sciences.

Influence of calcium on the thermal stabilization of bovine α-lactalbumin by selected polyols

J. Sancho, J. Lozano, C. M. Romero, 2011 .

Design of Ligand Binding to an Engineered Protein Cavity Using Virtual Screening and Thermal Up-shift Evaluation

Marta Bueno, Javier Sancho, Santiago Cuesta-López, 2005, J. Comput. Aided Mol. Des..

Inhibition of Pig Phosphoenolpyruvate Carboxykinase Isoenzymes by 3-Mercaptopicolinic Acid and Novel Inhibitors

A. Velázquez‐Campoy, J. Carrodeguas, J. Sancho, 2016, PloS one.

Identifying potential novel drugs against Helicobacter pylori by targeting the essential response regulator HsrA

A. Velázquez‐Campoy, Á. Lanas, J. Sancho, 2019, Scientific Reports.

, Tumani from The Gambia , West Africa Patterns among Helicobacter pylori Strains Antimicrobial Susceptibility and Resistance

R. Adegbola, J. Sancho, D. Berg, 2015 .

Antimicrobial Susceptibility and Resistance Patterns among Helicobacter pylori Strains from The Gambia, West Africa

R. Adegbola, J. Sancho, D. Berg, 2012, Antimicrobial Agents and Chemotherapy.

α‐helix stabilization by alanine relative to glycine: Roles of polar and apolar solvent exposures and of backbone entropy

J. Sancho, L. A. Campos, J. López-Llano, 2006, Proteins.

Discovery of specific flavodoxin inhibitors as potential therapeutic agents against Helicobacter pylori infection.

A. Velázquez‐Campoy, Á. Lanas, J. Sancho, 2009, ACS chemical biology.

Structural and Functional Studies on the Interaction of Sodium Dodecyl Sulfate with β-Galactosidase

A. Muga, J. Sancho, T. Bellón, 1993 .

Scrambled Isomers as Key Intermediates in the Oxidative Folding of Ligand Binding Module 5 of the Low Density Lipoprotein Receptor*

F. Avilés, J. Sancho, S. Ventura, 2008, Journal of Biological Chemistry.

Pathway of protein folding.

L Serrano, A. Fersht, L. Serrano, 1992, Faraday discussions.

Repurposing Dihydropyridines for Treatment of Helicobacter pylori Infection

A. Velázquez‐Campoy, Á. Lanas, J. Sancho, 2019, Pharmaceutics.

Redox- and Ligand Binding-Dependent Conformational Ensembles in the Human Apoptosis-Inducing Factor Regulate Its Pro-Life and Cell Death Functions.

A. Velázquez‐Campoy, J. Sancho, P. Ferreira, 2019, Antioxidants & redox signaling.

Anabaena apoflavodoxin hydrogen exchange: On the stable exchange core of the α/β(21345) flavodoxin‐like family

Javier Sancho, J. Sancho, M. Rico, 2001 .

Calculation of Protein Folding Thermodynamics Using Molecular Dynamics Simulations

J. Sancho, J. J. Galano-Frutos, Francho Nerín-Fonz, 2023, bioRxiv.

Stabilization of apoflavodoxin by replacing hydrogen-bonded charged Asp or Glu residues by the neutral isosteric Asn or Gln.

J. Sancho, M. P. Irún, S. Maldonado, 2001, Protein engineering.

Energetics of a hydrogen bond (charged and neutral) and of a cation-pi interaction in apoflavodoxin.

J. Fernández-Recio, J. Sancho, A. Romero, 1999, Journal of molecular biology.

Do proteins always benefit from a stability increase? Relevant and residual stabilisation in a three-state protein by charge optimisation.

R. Godoy-Ruiz, J. Sancho, M. M. Garcia-Mira, 2004, Journal of molecular biology.

Flavodoxins as Novel Therapeutic Targets against Helicobacter pylori and Other Gastric Pathogens

J. Sancho, S. Salillas, 2020, International journal of molecular sciences.

Thermal denaturation of α-chymotrypsinogen A in presence of polyols at pH 2.0 and pH 3.0

J. Sancho, C. M. Romero, Juan S. Abella, 2015, Journal of Thermal Analysis and Calorimetry.

FtsH cleavage of non-native conformations of proteins.

J. Sancho, T. Ogura, S. Nishikori, 2010, Journal of structural biology.

Design and structure of an equilibrium protein folding intermediate: a hint into dynamical regions of proteins.

Marta Bueno, Pau Bernadó, Vladimir Espinosa Angarica, 2010, Journal of molecular biology.

Thermodynamic study of the influence of polyols and glucose on the thermal stability of holo-bovine α-lactalbumin

J. Sancho, J. Lozano, C. M. Romero, 2009 .

Native‐specific stabilization of flavodoxin by the FMN cofactor: Structural and thermodynamical explanation

J. Sancho, L. A. Campos, J Sancho, 2006, Proteins.

Filling small, empty protein cavities: structural and energetic consequences.

M. Bueno, J. Sancho, J. Neira, 2006, Journal of molecular biology.

Equilibrium phi-analysis of a molten globule: the 1-149 apoflavodoxin fragment.

M. Bueno, J. Sancho, L. A. Campos, 2006, Journal of molecular biology.

The Long and Short Flavodoxins

J. Fernández-Recio, S. Jain, J. Sancho, 2004, Journal of Biological Chemistry.

Apoflavodoxin: structure, stability, and FMN binding.

J. Fernández-Recio, J. Sancho, M. P. Irún, 1998, Biochimie.

Conformational stability of apoflavodoxin

Manuel Cortijo, J. L. López-Lacomba, Javier Sancho, 1996, Protein science : a publication of the Protein Society.

Molten globule and native state ensemble of Helicobacter pylori flavodoxin: can crowding, osmolytes or cofactors stabilize the native conformation relative to the molten globule?

J. Sancho, N. Cremades, 2008, Biophysical journal.

VSDMIP: virtual screening data management on an integrated platform

Javier Sancho, Antonio Morreale, Angel R. Ortiz, 2009, J. Comput. Aided Mol. Des..

Direct examination of the relevance for folding, binding and electron transfer of a conserved protein folding intermediate.

A. Velázquez‐Campoy, S. Vega, J. Sancho, 2017, Physical chemistry chemical physics : PCCP.

Flavodoxins: sequence, folding, binding, function and beyond

J. Sancho, J. Sancho, 2006, Cellular and Molecular Life Sciences CMLS.

The Mycobacterium tuberculosis phoPR Operon Is Positively Autoregulated in the Virulent Strain H37Rv

J. Sancho, C. Soto, B. Gicquel, 2008, Journal of bacteriology.

Streptococcus pneumoniae TIGR4 Flavodoxin: Structural and Biophysical Characterization of a Novel Drug Target

A. Velázquez‐Campoy, J. Sancho, A. Rojas, 2016, PloS one.

In vivo reconstitution of a homodimeric cytochrome b559 like structure: The role of the N-terminus α-subunit from Synechocystis sp. PCC 6803.

J. Sancho, P. Alonso, R. Picorel, 2015, Journal of photochemistry and photobiology. B, Biology.

Inhibition of α-Synuclein Aggregation and Mature Fibril Disassembling With a Minimalistic Compound, ZPDm

X. Salvatella, J. Sancho, S. Ventura, 2020, Frontiers in Bioengineering and Biotechnology.

Theoretical Analysis of the Electron Spin Density Distribution of the Flavin Semiquinone Isoalloxazine Ring within Model Protein Environments

J. Mayoral, J. Sancho, M. Medina, 2002 .

Identification of Specific Pluripotent Stem Cell Death—Inducing Small Molecules by Chemical Screening

C. Antzelevitch, J. Carrodeguas, J. Sancho, 2012, Stem Cell Reviews and Reports.

Common conformational changes in flavodoxins induced by FMN and anion binding: The structure of Helicobacter pylori apoflavodoxin

Marta Bueno, Fernando Falo, Santiago Cuesta-López, 2007, Proteins.

Closure of a tyrosine/tryptophan aromatic gate leads to a compact fold in apo flavodoxin

Javier Sancho, Antonio Romero, J. Sancho, 1996, Nature Structural Biology.

Fluorescence spectrum of barnase: contributions of three tryptophan residues and a histidine-related pH dependence.

A. Fersht, J. Sancho, R. Loewenthal, 1991, Biochemistry.

Conformational Stability of Helicobacter pylori Flavodoxin

A. Velázquez‐Campoy, M. Bueno, J. Sancho, 2008, Journal of Biological Chemistry.

The flavodoxin from Helicobacter pylori: structural determinants of thermostability and FMN cofactor binding.

Nunilo Cremades, Javier Sancho, A. Velázquez‐Campoy, 2008, Biochemistry.

Histidine residues at the N- and C-termini of alpha-helices: perturbed pKas and protein stability.

A. Fersht, L. Serrano, J. Sancho, 1992, Biochemistry.

Review Flavodoxins: sequence, folding, binding, function and beyond

J. Sancho, Biología Molecular, 2006 .

A double-deletion method to quantifying incremental binding energies in proteins from experiment: example of a destabilizing hydrogen bonding pair.

J. Sancho, S. Cuesta-López, L. A. Campos, 2004, Biophysical journal.

Role of neighboring FMN side chains in the modulation of flavin reduction potentials and in the energetics of the FMN:apoprotein interaction in Anabaena flavodoxin.

I. Nogués, J. Sancho, M. Medina, 2004, Biochemistry.

Anabaena sp. PCC 7119 Flavodoxin as Electron Carrier from Photosystem I to Ferredoxin-NADP+Reductase

J. Sancho, M. Medina, M. A. De la Rosa, 2002, The Journal of Biological Chemistry.

Salt‐induced stabilization of apoflavodoxin at neutral pH is mediated through cation‐specific effects

B. García-Moreno E., J. Sancho, L. A. Campos, 2002, Protein science : a publication of the Protein Society.

Thermodynamics of protein‐cation interaction: Ca+2 and Mg+2 binding to the fifth binding module of the LDL receptor

A. Velázquez‐Campoy, J. Sancho, S. Cuesta-López, 2010, Proteins.

Structure of RdxA – an oxygen‐insensitive nitroreductase essential for metronidazole activation in Helicobacter pylori

J. Sancho, A. Rojas, P. Hoffman, 2012, The FEBS journal.

Dissection of an enzyme by protein engineering. The N and C-terminal fragments of barnase form a native-like complex with restored enzymic activity.

A. Fersht, J. Sancho, 1992, Journal of molecular biology.

An N-terminal fragment of barnase has residual helical structure similar to that in a refolding intermediate.

A. Fersht, J. Sancho, J. Neira, 1992, Journal of molecular biology.

Design, Synthesis, and Efficacy Testing of Nitroethylene- and 7-Nitrobenzoxadiazol-Based Flavodoxin Inhibitors against Helicobacter pylori Drug-Resistant Clinical Strains and in Helicobacter pylori-Infected Mice.

A. Velázquez‐Campoy, J. Carrodeguas, Á. Lanas, 2019, Journal of medicinal chemistry.

An extensive thermodynamic characterization of the dimerization domain of the HIV‐1 capsid protein

M. G. Mateu, M. Bueno, J. Sancho, 2005, Protein science : a publication of the Protein Society.

Identification of Inhibitors Targeting Ferredoxin-NADP+ Reductase from the Xanthomonas citri subsp. citri Phytopathogenic Bacteria

J. Sancho, M. Medina, M. L. Tondo, 2017, Molecules.

ZPD-2, a Small Compound That Inhibits α-Synuclein Amyloid Aggregation and Its Seeded Polymerization

X. Salvatella, J. Sancho, S. Ventura, 2019, Front. Mol. Neurosci..

Benzbromarone, Quercetin, and Folic Acid Inhibit Amylin Aggregation

J. Carrodeguas, J. Sancho, S. Ventura, 2016, International journal of molecular sciences.

Selective Targeting of Human and Animal Pathogens of the Helicobacter Genus by Flavodoxin Inhibitors: Efficacy, Synergy, Resistance and Mechanistic Studies

A. Velázquez‐Campoy, J. Sancho, U. Schaible, 2021, International journal of molecular sciences.

Low‐density lipoprotein receptor is a calcium/magnesium sensor – role of LR4 and LR5 ion interaction kinetics in low‐density lipoprotein release in the endosome

A. Velázquez‐Campoy, J. Sancho, X. Arias-Moreno, 2014, The FEBS journal.

A pyrene-inhibitor fluorescent probe with large Stokes shift for the staining of Aβ1–42, α-synuclein, and amylin amyloid fibrils as well as amyloid-containing Staphylococcus aureus biofilms

J. Sancho, S. Ventura, I. Pallarès, 2018, Analytical and Bioanalytical Chemistry.

Four-state equilibrium unfolding of an scFv antibody fragment.

Javier Sancho, J. Sancho, M. P. Irún, 2002, Biochemistry.

Computational diagnosis of protein conformational diseases: Short molecular dynamics simulations reveal a fast unfolding of r‐LDL mutants that cause familial hypercholesterolemia

J. Sancho, S. Cuesta-López, F. Falo, 2006, Proteins.

Contribution of disulfide bonds to stability, folding, and amyloid fibril formation: the PI3-SH3 domain case.

A. Velázquez‐Campoy, J. Sancho, Ricardo Graña-Montes, 2012, Antioxidants & redox signaling.

Intradomain Confinement of Disulfides in the Folding of Two Consecutive Modules of the LDL Receptor

J. Sancho, S. Ventura, H. Fraga, 2015, PloS one.

Differential stabilization of the three FMN redox forms by tyrosine 94 and tryptophan 57 in flavodoxin from Anabaena and its influence on the redox potentials.

J. Sancho, A. Lostao, S. Mayhew, 1997, Biochemistry.

Long-range surface charge-charge interactions in proteins. Comparison of experimental results with calculations from a theoretical method.

A. Fersht, J. Sancho, R. Loewenthal, 1993, Journal of molecular biology.

Do proteins with similar folds have similar transition state structures? A diffuse transition state of the 169 residue apoflavodoxin.

Marta Bueno, Javier Sancho, Sara Ayuso-Tejedor, 2006, Journal of molecular biology.

Defining the Nature of Thermal Intermediate in 3 State Folding Proteins: Apoflavodoxin, a Study Case

Modesto Orozco, Pau Bernadó, Rebeca García-Fandiño, 2012, PLoS Comput. Biol..

Helix propensities of conformationally restricted amino acids. Non-natural substitutes for helix breaking proline and helix forming alanine.

J. Fernández-Recio, J. Sancho, C. Cativiela, 2010, Organic & biomolecular chemistry.

Biophysical Screening for Identifying Pharmacological Chaperones and Inhibitors Against Conformational and Infectious Diseases.

O. Abián, A. Velázquez‐Campoy, S. Vega, 2016, Current drug targets.

The native-state ensemble of proteins provides clues for folding, misfolding and function.

Nunilo Cremades, Javier Sancho, E. Freire, 2006, Trends in biochemical sciences.

Mapping transition states of protein unfolding by protein engineering of ligand-binding sites.

A. Fersht, E. Meiering, J. Sancho, 1991, Journal of molecular biology.

Improved flavodoxin inhibitors with potential therapeutic effects against Helicobacter pylori infection.

A. Velázquez‐Campoy, J. Sancho, P. Hoffman, 2013, Journal of medicinal chemistry.

Unravelling the Complex Denaturant and Thermal-Induced Unfolding Equilibria of Human Phenylalanine Hydroxylase

J. Sancho, María Conde-Giménez, 2021, International journal of molecular sciences.

Structural and functional studies on the interaction of sodium dodecyl sulfate with beta-galactosidase.

A. Muga, J. Sancho, T. Bellón, 1993, Archives of biochemistry and biophysics.

Intrahelical side chain interactions in α‐helices: poor correlation between energetics and frequency

J. Fernández-Recio, J. Sancho, 1998, FEBS letters.

Comparison of DNA binding across protein superfamilies

B. Contreras-Moreira, J. Sancho, V. E. Angarica, 2010, Proteins.

LDL receptor/lipoprotein recognition: endosomal weakening of ApoB and ApoE binding to the convex face of the LR5 repeat

A. Velázquez‐Campoy, J. Sancho, X. Arias-Moreno, 2014, The FEBS journal.

Helix propensities of conformationally restricted amino acids. Non-natural substitutes for helix breaking proline and helix forming alanine.

J. Fernández-Recio, J. Sancho, C. Cativiela, 2010, Organic & biomolecular chemistry.

Direct examination of the relevance for folding, binding and electron transfer of a conserved protein folding intermediate.

A. Velázquez‐Campoy, S. Vega, J. Sancho, 2017, Physical chemistry chemical physics : PCCP.

Molecular Interactions and Forces that Make Proteins Stable: A Quantitative Inventory from Atomistic Molecular Dynamics Simulations

J. Sancho, J. J. Galano-Frutos, 2023, bioRxiv.

Accurate Calculation of Barnase and SNase Folding Energetics Using Short Molecular Dynamics Simulations and an Atomistic Model of the Unfolded Ensemble: Evaluation of Force Fields and Water Models

J. Sancho, J. J. Galano-Frutos, 2019, J. Chem. Inf. Model..

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