Shivendra V. Singh

发表

p53 Regulates Cellular Responses to Environmental Carcinogen Benzo[a]pyrene-7,8-diol-9,10-epoxide in Human Lung Cancer Cells

Hui Xiao, Shivendra V. Singh, 2007, Cell cycle.

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

Cells and Apoptosis in Human Prostate Cancer c Cytochrome Sulforaphane Causes Autophagy to Inhibit Release of Updated

Shivendra V. Singh, A. Herman-Antosiewicz, Daniel E. Johnson, 2006 .

Orphan nuclear receptor pregnane X receptor sensitizes oxidative stress responses in transgenic mice and cancerous cells.

Shivendra V. Singh, B. Day, V. Kagan, 2006, Molecular endocrinology.

Transcriptional Repression and Inhibition of Nuclear Translocation of Androgen Receptor by Diallyl Trisulfide in Human Prostate Cancer Cells

Shivendra V. Singh, Silvia D. Stan, 2009, Clinical Cancer Research.

CXCR4 Is a Novel Target of Cancer Chemopreventative Isothiocyanates in Prostate Cancer Cells

Rahul Parikh, Shivendra V. Singh, Rahul Parikh, 2015, Cancer Prevention Research.

Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits proliferation of human prostate cancer cells by causing G2/M arrest and inducing apoptosis.

S. Srivastava, Yan Zeng, Shivendra V. Singh, 2003, Carcinogenesis.

Sulforaphane induces caspase-mediated apoptosis in cultured PC-3 human prostate cancer cells and retards growth of PC-3 xenografts in vivo.

R. Dhir, Shivendra V. Singh, D. Xiao, 2003, Carcinogenesis.

Diallyl trisulfide-induced apoptosis in human prostate cancer cells involves c-Jun N-terminal kinase and extracellular-signal regulated kinase-mediated phosphorylation of Bcl-2

Shivendra V. Singh, D. Trump, Candace S. Johnson, 2004, Oncogene.

Caspase-Dependent Apoptosis Induction by Phenethyl Isothiocyanate, a Cruciferous Vegetable-Derived Cancer Chemopreventive Agent, Is Mediated by Bak and Bax

J. Nelson, Yan Zeng, Shivendra V. Singh, 2005, Clinical Cancer Research.

Atg5 regulates phenethyl isothiocyanate-induced autophagic and apoptotic cell death in human prostate cancer cells.

Alfred L. Fisher, Shivendra V. Singh, D. Xiao, 2009, Cancer research.

Sulforaphane inhibits prostate carcinogenesis and pulmonary metastasis in TRAMP mice in association with increased cytotoxicity of natural killer cells.

S. Amin, D. Desai, Yan Zeng, 2009, Cancer research.

Sulforaphane Inhibits Constitutive and Interleukin-6–Induced Activation of Signal Transducer and Activator of Transcription 3 in Prostate Cancer Cells

Shivendra V. Singh, Eun-Ryeong Hahm, 2010, Cancer Prevention Research.

Diallyl trisulfide‐induced apoptosis in human cancer cells is linked to checkpoint kinase 1‐mediated mitotic arrest

Yan Zeng, Shivendra V. Singh, D. Xiao, 2009, Molecular carcinogenesis.

Induction of p21 protein protects against sulforaphane-induced mitotic arrest in LNCaP human prostate cancer cell line

Hui Xiao, Shivendra V. Singh, A. Herman-Antosiewicz, 2007, Molecular Cancer Therapeutics.

JS-K, a glutathione/glutathione S-transferase-activated nitric oxide donor of the diazeniumdiolate class with potent antineoplastic activity.

K. M. Davies, X. Ji, Shivendra V. Singh, 2003, Molecular cancer therapeutics.

Benzyl isothiocyanate–induced apoptosis in human breast cancer cells is initiated by reactive oxygen species and regulated by Bax and Bak

Shivendra V. Singh, D. Xiao, V. Vogel, 2006, Molecular Cancer Therapeutics.

Leelamine Is a Novel Lipogenesis Inhibitor in Prostate Cancer Cells In Vitro and In Vivo

Shivendra V. Singh, S. Pore, Krishna B Singh, 2019, Molecular Cancer Therapeutics.

Irreversible Inhibition of Glutathione S-Transferase by Phenethyl Isothiocyanate (PEITC), a Dietary Cancer Chemopreventive Phytochemical

X. Ji, Shivendra V. Singh, M. Dyba, 2016, PloS one.

Specificity of Glutathione S-Transferases in the Glutathione Conjugation of Carcinogenic Diol Epoxides

Hui Xiao, Shivendra V. Singh, 2006 .

Inhibition of EGFR-STAT 3 Signaling with Erlotinib Prevents Carcinogenesis in a Chemically-Induced Mouse Model of Oral Squamous Cell Carcinoma

Daniel B. Neill, D. Neill, R. Seethala, 2011 .

Inhibition of EGFR-STAT3 Signaling with Erlotinib Prevents Carcinogenesis in a Chemically-Induced Mouse Model of Oral Squamous Cell Carcinoma

Daniel B. Neill, D. Neill, R. Seethala, 2010, Cancer Prevention Research.

Phenethyl isothiocyanate-induced apoptosis in p53-deficient PC-3 human prostate cancer cell line is mediated by extracellular signal-regulated kinases.

Shivendra V. Singh, D. Xiao, 2002, Cancer research.

Ayurvedic Medicine Constituent Withaferin A Causes G2 and M Phase Cell Cycle Arrest in Human Breast Cancer Cells

Yan Zeng, Shivendra V. Singh, Silvia D. Stan, 2008, Nutrition and cancer.

Withaferin A Causes FOXO 3 aand Bim-Dependent Apoptosis and Inhibits Growth of Human Breast Cancer Cells In Vivo

Shivendra V. Singh, Silvia D. Stan, Eun-Ryeong Hahm, 2008 .

Cholesterol depletion by methyl-β-cyclodextrin augments tamoxifen induced cell death by enhancing its uptake in melanoma

Shivendra V. Singh, M. Bhat, M. Kulkarni, 2014, Molecular Cancer.

Sulforaphane-induced Cell Death in Human Prostate Cancer Cells Is Initiated by Reactive Oxygen Species*

Simon C Watkins, S. Srivastava, Yan Zeng, 2005, Journal of Biological Chemistry.

The FoxQ1 transcription factor is a novel regulator of electron transport chain complex I subunits in human breast cancer cells

Shivendra V. Singh, Su-Hyeong Kim, 2021, Molecular carcinogenesis.

Role of Krüppel-like Factor 4-p21CIP1 Axis in Breast Cancer Stem-like Cell Inhibition by Benzyl Isothiocyanate

Shivendra V. Singh, Su-Hyeong Kim, 2019, Cancer Prevention Research.

Inhibition of Glycolysis in Prostate Cancer Chemoprevention by Phenethyl Isothiocyanate

Jian-Min Yuan, L. Rigatti, Shivendra V. Singh, 2018, Cancer Prevention Research.

c-Myc is a novel target of cell cycle arrest by honokiol in prostate cancer cells

Shivendra V. Singh, Krishna B Singh, Eun-Ryeong Hahm, 2016, Cell cycle.

Sulforaphane Inhibits c‐Myc‐Mediated Prostate Cancer Stem‐Like Traits

Shivendra V. Singh, Krishna B Singh, Avani Vyas, 2016, Journal of cellular biochemistry.

Diallyl trisulfide-induced G2–M phase cell cycle arrest in human prostate cancer cells is caused by reactive oxygen species-dependent destruction and hyperphosphorylation of Cdc25C

J. Lazo, Hui Xiao, Shivendra V. Singh, 2005, Oncogene.

Diallyl trisulfide, a constituent of processed garlic, inactivates Akt to trigger mitochondrial translocation of BAD and caspase-mediated apoptosis in human prostate cancer cells.

Shivendra V. Singh, D. Xiao, 2006, Carcinogenesis.

The Role of Forkhead Box Q1 Transcription Factor in Anticancer Effects of Withaferin A in Breast Cancer

Shivendra V. Singh, Krishna B Singh, Eun-Ryeong Hahm, 2021, Cancer Prevention Research.

Zerumbone modulates CD1d expression and lipid antigen presentation pathway in breast cancer cells.

R. Singh, Shivendra V. Singh, Ritis K. Shyanti, 2017, Toxicology in vitro : an international journal published in association with BIBRA.

An Alpha Class Mouse Glutathione S-Transferase with Exceptional Catalytic Efficiency in the Conjugation of Glutathione with 7β,8α-Dihydroxy-9α,10α-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene*

S. Srivastava, Shivendra V. Singh, Y. Awasthi, 1996, The Journal of Biological Chemistry.

Benzyl isothiocyanate inhibits oncogenic actions of leptin in human breast cancer cells by suppressing activation of signal transducer and activator of transcription 3.

Shivendra V. Singh, D. Sharma, A. Nagalingam, 2011, Carcinogenesis.

Inherent and Acquired Resistance to Paclitaxel in Hepatocellular Carcinoma: Molecular Events Involved

Shivendra V. Singh, M. Bhat, R. Kumari, 2013, PloS one.

Food Components, Alternative Medicine, and Cancer: Progress and Promise

R. Cooney, Shivendra V. Singh, B. Rigas, 2008, Nutrition and Cancer.

Zerumbone causes Bax- and Bak-mediated apoptosis in human breast cancer cells and inhibits orthotopic xenograft growth in vivo

Shivendra V. Singh, A. Murakami, J. Arlotti, 2012, Breast Cancer Research and Treatment.

Gene Expression Changes by Diallyl Trisulfide Administration in Chemically-induced Mammary Tumors in Rats

Shivendra V. Singh, Eun-Ryeong Hahm, 2022, Journal of cancer prevention.

Forkhead Box Q1 Is a Novel Target of Breast Cancer Stem Cell Inhibition by Diallyl Trisulfide*

Adrian V. Lee, Shivendra V. Singh, N. Priedigkeit, 2016, The Journal of Biological Chemistry.

The Role of Lysosome-associated Membrane Protein 2 in Prostate Cancer Chemopreventive Mechanisms of Sulforaphane

Shivendra V. Singh, Krishna B Singh, Eun-Ryeong Hahm, 2020, Cancer Prevention Research.

Diallyl Trisulfide Inhibits Angiogenic Features of Human Umbilical Vein Endothelial Cells by Causing Akt Inactivation and Down-Regulation of VEGF and VEGF-R2

Yan Zeng, Hui Xiao, Shivendra V. Singh, 2006, Nutrition and cancer.

Diallyl Trisulfide Suppresses Growth of PC-3 Human Prostate Cancer Xenograft In vivo in Association with Bax and Bak Induction

R. Dhir, Young-ae Kim, Yan Zeng, 2006, Clinical Cancer Research.

Modulation of doxorubicin cytotoxicity by ethacrynic acid

S. Srivastava, Shivendra V. Singh, Y. Awasthi, 1996, International journal of cancer.

Transfection with 4-hydroxynonenal-metabolizing glutathione S-transferase isozymes leads to phenotypic transformation and immortalization of adherent cells.

Shivendra V. Singh, Y. Awasthi, Abha Sharma, 2004, European journal of biochemistry.

Catalytic efficiencies of allelic variants of human glutathione S-transferase Pi in the glutathione conjugation of α,β-unsaturated aldehydes

Shivendra V. Singh, P. Zimniak, Xun Hu, 2000 .

Exceptional activity of murine glutathione transferase A1‐1 against (7R,8S)‐dihydroxy‐(9S,10R)‐epoxy‐7,8,9,10‐tetrahydrobenzo[a]pyrene–induced DNA damage in stably transfected cells

Shivendra V. Singh, S. Pan, Jianxia Guo, 2003, Molecular carcinogenesis.

Differential expression of glutathione S-transferase isoenzymes in murine small intestine and colon.

Shivendra V. Singh, Jianxia Guo, J. Orchard, 2002, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

DNA Damage in HepG2 Cells Stably Transfected with Allelic Variants of p Class Human Glutathione S-Transferase 1

Shivendra V. Singh, C. Herzog, P. Zimniak, 1999 .

Active Site Architecture of Polymorphic Forms of Human GlutathioneS-Transferase P1-1 Accounts for Their Enantioselectivity and Disparate Activity in the Glutathione Conjugation of 7β,8α-Dihydroxy-9α, 10α-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene

S. Srivastava, X. Ji, Shivendra V. Singh, 1997 .

Induction of glutathione S‐transferase π as a bioassay for the evaluation of potency of inhibitors of benzo(a)pyrene‐induced cancer in a murine model

S. Srivastava, Shivendra V. Singh, Y. Awasthi, 1997, International journal of cancer.

Growth Arrest by the Antitumor Steroidal Lactone Withaferin A in Human Breast Cancer Cells Is Associated with Down-regulation and Covalent Binding at Cysteine 303 of β-Tubulin*

A. Marcus, P. Wipf, X. Ji, 2013, The Journal of Biological Chemistry.

Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells.

Shivendra V. Singh, D. Trump, Candace S. Johnson, 2004, Molecular cancer therapeutics.

Withania somnifera: From prevention to treatment of cancer.

Shivendra V. Singh, T. Kensler, D. Palliyaguru, 2016, Molecular nutrition & food research.

Role of mitogen‐activated protein kinases and Mcl‐1 in apoptosis induction by withaferin A in human breast cancer cells

Shivendra V. Singh, Eun-Ryeong Hahm, Joomin Lee, 2014, Molecular carcinogenesis.

MPTP metabolites inhibit rat brain glutathione S-transferases

A. Brossi, Shivendra V. Singh, Y. Awasthi, 1987, Neuroscience Letters.

Role of reactive oxygen intermediates in cellular responses to dietary cancer chemopreventive agents.

Shivendra V. Singh, J. Antosiewicz, S. Kar, 2008, Planta medica.

Requirement of a carbon spacer in benzyl isothiocyanate-mediated cytotoxicity and MAPK activation in head and neck squamous cell carcinoma.

J. Grandis, Shivendra V. Singh, D. Xiao, 2003, Carcinogenesis.

Critical role of allyl groups and disulfide chain in induction of Pi class glutathione transferase in mouse tissues in vivo by diallyl disulfide, a naturally occurring chemopreventive agent in garlic.

S. Srivastava, Shivendra V. Singh, C. Bose, 2002, Carcinogenesis.

Differential expression of α, μ and π classes of isozymes of glutathione S-transferase in bovine lens, cornea, and retina

A. Kurosky, G. Ansari, Shivendra V. Singh, 1988 .

Effect of buthionine sulfoximine and ethacrynic acid on cytotoxic activity of mitomycin C analogues BMY 25282 and BMY 25067.

Bing-he Xu, Shivendra V. Singh, S. Singh, 1992, Cancer research.

Evaluation of Biodistribution of Sulforaphane after Administration of Oral Broccoli Sprout Extract in Melanoma Patients with Multiple Atypical Nevi

Amy Rose, J. Kirkwood, H. Zarour, 2018, Cancer Prevention Research.

Immunocytochemical evidence for the expression of GST1, GST2, and GST3 gene loci for glutathione S-transferase in human lung

Shivendra V. Singh, Y. Awasthi, H. Ahmad, 2007, Lung.

Fighting Cancer with Phytochemicals from Allium Vegetables

R. Singh, Shivendra V. Singh, Sivapar V. Mathan, 2017 .

Molecular mechanisms and targets of cancer chemoprevention by garlic-derived bioactive compound diallyl trisulfide.

Shivendra V. Singh, M. Antony, Marie L Antony, 2011, Indian journal of experimental biology.

Diallyl Trisulfide-Induced G2/M Phase Cell Cycle Arrest in DU145 Cells Is Associated with Delayed Nuclear Translocation of Cyclin-Dependent Kinase 1

Young-ae Kim, Shivendra V. Singh, D. Xiao, 2010, Pharmaceutical Research.

Multitargeted prevention and therapy of cancer by diallyl trisulfide and related Allium vegetable-derived organosulfur compounds.

Shivendra V. Singh, A. Powolny, 2008, Cancer letters.

Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak

Young-ae Kim, Zhou Wang, Yan Zeng, 2007, Molecular Cancer Therapeutics.

Molecular targets of cancer chemoprevention by garlic-derived organosulfides

Shivendra V. Singh, A. Herman-Antosiewicz, A. Powolny, 2007, Acta Pharmacologica Sinica.

c-Jun NH2-Terminal Kinase Signaling Axis Regulates Diallyl Trisulfide–Induced Generation of Reactive Oxygen Species and Cell Cycle Arrest in Human Prostate Cancer Cells

Shivendra V. Singh, J. Antosiewicz, A. Herman-Antosiewicz, 2006 .

Cellular Responses to Cancer Chemopreventive Agent D,L-Sulforaphane in Human Prostate Cancer Cells Are Initiated by Mitochondrial Reactive Oxygen Species

S. Amin, D. Desai, Yan Zeng, 2009, Pharmaceutical Research.

Targeting KDM4 for treating PAX3-FOXO1–driven alveolar rhabdomyosarcoma

Shondra M. Pruett-Miller, Taosheng Chen, Beisi Xu, 2022, Science Translational Medicine.

Prevention of Prostate Cancer in Transgenic Adenocarcinoma of the Mouse Prostate Mice by Yellow Passion Fruit Extract and Antiproliferative Effects of Its Bioactive Compound Piceatannol

Shivendra V. Singh, V. Cagnon, L. Kido, 2020, Journal of cancer prevention.

Benzo[a]pyrene-7,8-diol-9,10-epoxide causes caspase-mediated apoptosis in H460 human lung cancer cell line

Hui Xiao, Shivendra V. Singh, Eun-Ryeong Hahm, 2007, Cell cycle.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

Accelerated Metabolism and Exclusion of 4-Hydroxynonenal through Induction of RLIP76 and hGST5.8 Is an Early Adaptive Response of Cells to Heat and Oxidative Stress*

Shivendra V. Singh, Y. Awasthi, Abha Sharma, 2001, The Journal of Biological Chemistry.

Cytoprotective autophagy induction by withaferin A in prostate cancer cells involves GABARAPL1.

Shivendra V. Singh, Eun-Ryeong Hahm, 2020, Molecular carcinogenesis.

Therapeutic Potential of Leelamine, a Novel Inhibitor of Androgen Receptor and Castration-Resistant Prostate Cancer

X. Ji, Shivendra V. Singh, Krishna B Singh, 2018, Molecular Cancer Therapeutics.

Notch Activation Is Dispensable for D, L-Sulforaphane-Mediated Inhibition of Human Prostate Cancer Cell Migration

S. Amin, D. Desai, Shivendra V. Singh, 2012, PloS one.

Abstract #18: Cellular responses to cancer chemopreventive agent D,L-sulforaphane in human prostate cancer cells are initiated by the mitochondria-derived reactive oxygen species

Yan Zeng, Shivendra V. Singh, D. Xiao, 2009 .

Honokiol activates reactive oxygen species‐mediated cytoprotective autophagy in human prostate cancer cells

Shivendra V. Singh, Kozue Sakao, Eun-Ryeong Hahm, 2014, The Prostate.

Differential Effects of Phenethyl Isothiocyanate and D,L-Sulforaphane on TLR3 Signaling

Shivendra V. Singh, Elizabeth M. Coyle, Jianzhong Zhu, 2013, The Journal of Immunology.

TLR3 Signaling Isothiocyanate and D,L-Sulforaphane on Differential Effects of Phenethyl

Shivendra V. Singh, Elizabeth M. Coyle, Jianzhong Zhu, 2013 .

Leelamine suppresses cMyc expression in prostate cancer cells in vitro and inhibits prostate carcinogenesis in vivo.

Shivendra V. Singh, Krishna B Singh, Eun-Ryeong Hahm, 2021, Journal of cancer metastasis and treatment.

Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms.

Shivendra V. Singh, D. Chartoumpekis, T. Kensler, 2016, Free radical biology & medicine.

Withaferin A induces Nrf 2-dependent protection against liver injury : role of Keap 1-independent mechanisms

Shivendra V. Singh, D. Chartoumpekis, T. Kensler, 2016 .

Bax and Bak are required for apoptosis induction by sulforaphane, a cruciferous vegetable-derived cancer chemopreventive agent.

Shivendra V. Singh, Sunga Choi, 2005, Cancer research.

Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits growth of PC-3 human prostate cancer xenografts in vivo

S. Srivastava, Shivendra V. Singh, D. Kokkinakis, 2003 .

The Use of Seahorse Extracellular Flux Analyzer in Mechanistic Studies of Naturally Occurring Cancer Chemopreventive Agents

Shivendra V. Singh, B. V. Houten, Eun-Ryeong Hahm, 2014 .

Inhibition of mitochondrial fusion is an early and critical event in breast cancer cell apoptosis by dietary chemopreventative benzyl isothiocyanate.

Simon C Watkins, R. Singh, Shivendra V. Singh, 2016, Mitochondrion.

D,L‐sulforaphane‐induced apoptosis in human breast cancer cells is regulated by the adapter protein p66Shc

Shivendra V. Singh, Kozue Sakao, 2012, Journal of cellular biochemistry.

p66 Shc Is Indispensable for Phenethyl Isothiocyanate – Induced Apoptosis in Human Prostate Cancer Cells

Shivendra V. Singh, D. Xiao, 2010 .

Extracellular Signal-regulated Kinases PC-3 Human Prostate Cancer Cell Line Is Mediated by Phenethyl Isothiocyanate-induced Apoptosis in p 53-deficient Updated

Shivendra V. Singh, 2002 .

Signal transduction pathways leading to cell cycle arrest and apoptosis induction in cancer cells by Allium vegetable-derived organosulfur compounds: a review.

Shivendra V. Singh, A. Herman-Antosiewicz, 2004, Mutation research.

Monocarboxylate transporter 1 is a novel target for breast cancer stem like‐cell inhibition by diallyl trisulfide

Shivendra V. Singh, Su-Hyeong Kim, 2022, Molecular carcinogenesis.

Breast Cancer Selective Disruption of Actin Cytoskeleton by Diallyl Trisulfide

Shivendra V. Singh, Eun-Ryeong Hahm, Rana P. Singh, 2022, Journal of cancer prevention.

c-Jun NH(2)-terminal kinase signaling axis regulates diallyl trisulfide-induced generation of reactive oxygen species and cell cycle arrest in human prostate cancer cells.

Shivendra V. Singh, J. Antosiewicz, A. Herman-Antosiewicz, 2006, Cancer research.

Phenethyl isothiocyanate, a cancer chemopreventive constituent of cruciferous vegetables, inhibits cap-dependent translation by regulating the level and phosphorylation of 4E-BP1.

N. Sonenberg, Shivendra V. Singh, Jing Hu, 2007, Cancer research.

Autophagy fails to alter withaferin A-mediated lethality in human breast cancer cells.

Shivendra V. Singh, Eun-Ryeong Hahm, 2013, Current cancer drug targets.

Diallyl trisulfide inhibits estrogen receptor-α activity in human breast cancer cells

Shivendra V. Singh, Eun-Ryeong Hahm, 2014, Breast Cancer Research and Treatment.

ATP-dependent transport of glutathione conjugate of 7 b ,8 a -dihydroxy-9 a ,10 a -oxy-7,8,9,10-tetrahydrobenzo[ a ]pyrene in murine hepatic canalicular plasma membrane vesicles

S. Srivastava, Shivendra V. Singh, S. Awasthi, 1998 .

Tubulin β Cysteine 303 of Down-regulation and Covalent Binding at Cancer Cells Is Associated with Lactone Withaferin A in Human Breast Growth Arrest by the Antitumor Steroidal Signal Transduction

A. Marcus, P. Wipf, X. Ji, 2014 .

Withaferin A-Induced Apoptosis in Human Breast Cancer Cells Is Mediated by Reactive Oxygen Species

B. Van Houten, Shivendra V. Singh, S. Shiva, 2011, PloS one.

Withaferin A inhibits activation of signal transducer and activator of transcription 3 in human breast cancer cells.

Shivendra V. Singh, Eun-Ryeong Hahm, Joomin Lee, 2010, Carcinogenesis.

Pulmonary biochemical response to slate dust in rats

Shivendra V. Singh, M. F. Khan, Q. Rahman, 1984, Journal of applied toxicology : JAT.

Scientific Evidence for Anticancer Effects of Withania somnifera and Its Primary Bioactive Component Withaferin A

Shivendra V. Singh, Eun-Ryeong Hahm, S. Samanta, 2017 .

Mechanistic elucidation of the antitumor properties of withaferin a in breast cancer.

Shivendra V. Singh, D. Sharma, A. Nagalingam, 2014, Cancer research.

Withania somnifera Root Extract Inhibits Mammary Cancer Metastasis and Epithelial to Mesenchymal Transition

A. Marcus, Shivendra V. Singh, P. Vertino, 2013, PloS one.

Withaferin A causes FOXO3a- and Bim-dependent apoptosis and inhibits growth of human breast cancer cells in vivo.

Shivendra V. Singh, Silvia D. Stan, Eun-Ryeong Hahm, 2008, Cancer research.

Diallyl trisulfide selectively causes Bax‐ and Bak‐mediated apoptosis in human lung cancer cells

S. Ramalingam, Young-ae Kim, Yan Zeng, 2009, Environmental and molecular mutagenesis.

Diallyl Trisulfide Inhibits Leptin-induced Oncogenic Signaling in Human Breast Cancer Cells but Fails to Prevent Chemically-induced Luminal-type Cancer in Rats

Shivendra V. Singh, Krishna B Singh, Eun-Ryeong Hahm, 2020, Journal of cancer prevention.

Prostate cancer chemoprevention by sulforaphane in a preclinical mouse model is associated with inhibition of fatty acid metabolism

Shivendra V. Singh, B. Jacobs, S. Pore, 2018, Carcinogenesis.

p53-Independent Apoptosis by Benzyl Isothiocyanate in Human Breast Cancer Cells Is Mediated by Suppression of XIAP Expression

Shivendra V. Singh, Su-Hyeong Kim, 2010, Cancer Prevention Research.

The Role of Organosulfur Compounds Derived From Allium Vegetables in Cancer Prevention and Therapy

Shivendra V. Singh, Z. Witczak, D. McCune, 2016 .

Bioactive food components and cancer risk reduction

Shivendra V. Singh, S. Kar, G. Stoner, 2008, Journal of cellular biochemistry.

Checkpoint Kinase 1 Regulates Diallyl Trisulfide-induced Mitotic Arrest in Human Prostate Cancer Cells*

Shivendra V. Singh, A. Herman-Antosiewicz, 2005, Journal of Biological Chemistry.

Critical Role of p53 Upregulated Modulator of Apoptosis in Benzyl Isothiocyanate-Induced Apoptotic Cell Death

Shivendra V. Singh, M. Antony, Su-Hyeong Kim, 2012, PloS one.

Monitoring of Brucella infection associated with reproductive losses using multiple serological tests in organized goat and sheep flocks

Namita Singh, Shivendra V. Singh, Varsha Gupta, 2000 .

Ginsenoside Rh2-mediated G1 Phase Cell Cycle Arrest in Human Breast Cancer Cells Is Caused by p15Ink4B and p27Kip1-dependent Inhibition of Cyclin-dependent Kinases

Shivendra V. Singh, Sunga Choi, Tae Woong Kim, 2009, Pharmaceutical Research.

Caspase-dependent apoptosis induction by guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, in PC-3 human prostate cancer cells is mediated by Bax and Bak

R. Dhir, J. Nelson, Yan Zeng, 2005, Molecular Cancer Therapeutics.

z-Guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, inhibits angiogenesis in vitro and in vivo

Shivendra V. Singh, D. Xiao, 2008, Molecular Cancer Therapeutics.

Guggulsterone-induced apoptosis in human prostate cancer cells is caused by reactive oxygen intermediate dependent activation of c-Jun NH2-terminal kinase.

Yan Zeng, Shivendra V. Singh, D. Xiao, 2007, Cancer research.

Terminal Kinase 2 Dependent Activation of c-Jun NH − Cancer Cells Is Caused by Reactive Oxygen Intermediate Guggulsterone-Induced Apoptosis in Human Prostate

Yan Zeng, Shivendra V. Singh, D. Xiao, 2007 .

Reactive Oxygen Species-Dependent Apoptosis by Gugulipid Extract of Ayurvedic Medicine Plant Commiphora mukul in Human Prostate Cancer Cells Is Regulated by c-Jun N-Terminal Kinase

Yan Zeng, Shivendra V. Singh, D. Xiao, 2011, Molecular Pharmacology.

The garlic constituent diallyl trisulfide increases the lifespan of C. elegans via skn-1 activation

Alan Hubbard, Anna A. Powolny, Shivendra V. Singh, 2011, Experimental Gerontology.

Reactive Oxygen Species-Dependent Apoptosis by Gugulipid Extract of Ayurvedic Medicine Plant Commiphora mukul in Human Prostate Cancer Cells Is Regulated by c-Jun

Yan Zeng, Shivendra V. Singh, D. Xiao, 2011 .

Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3.

Daniel B. Neill, D. Neill, R. Seethala, 2009, Carcinogenesis.

Prevention of breast cancer-induced osteolytic bone resorption by benzyl isothiocyanate

Shivendra V. Singh, S. Pore, C. Anderson, 2018, Carcinogenesis.

Withaferin A inhibits experimental epithelial–mesenchymal transition in MCF‐10A cells and suppresses vimentin protein level in vivo in breast tumors

A. Marcus, Shivendra V. Singh, Eun-Ryeong Hahm, 2015, Molecular carcinogenesis.

Chemoprevention of prostate cancer by d,l-sulforaphane is augmented by pharmacological inhibition of autophagy.

Simon C Watkins, D. Stolz, S. Amin, 2013, Cancer research.

Chemoprevention strategies for pancreatic cancer

R. Brand, Shivendra V. Singh, Silvia D. Stan, 2010, Nature Reviews Gastroenterology &Hepatology.

D,L-Sulforaphane-induced cell death in human prostate cancer cells is regulated by inhibitor of apoptosis family proteins and Apaf-1.

Hui Xiao, Shivendra V. Singh, D. Xiao, 2007, Carcinogenesis.

A Comprehensive Review and Perspective on Anticancer Mechanisms of Withaferin A in Breast Cancer

Shivendra V. Singh, Krishna B Singh, Eun-Ryeong Hahm, 2020, Cancer Prevention Research.

Notch2 activation is protective against anticancer effects of zerumbone in human breast cancer cells

Shivendra V. Singh, Kozue Sakao, A. Sehrawat, 2014, Breast Cancer Research and Treatment.

Withaferin a suppresses estrogen receptor‐α expression in human breast cancer cells

Shivendra V. Singh, Yi Huang, Eun-Ryeong Hahm, 2011, Molecular carcinogenesis.

Withaferin A inhibits in vivo growth of breast cancer cells accelerated by Notch2 knockdown

Shivendra V. Singh, S. Thorne, A. Lokshin, 2016, Breast Cancer Research and Treatment.

Fatty Acid Synthesis Intermediates Represent Novel Noninvasive Biomarkers of Prostate Cancer Chemoprevention by Phenethyl Isothiocyanate

Shivendra V. Singh, Krishna B Singh, 2017, Cancer Prevention Research.

KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma

Beisi Xu, A. Davidoff, Shivendra V. Singh, 2020, Nature Communications.

Phenethyl Isothiocyanate Inhibits Oxidative Phosphorylation to Trigger Reactive Oxygen Species-mediated Death of Human Prostate Cancer Cells*

Daniel Normolle, Dong Xiao, B. Van Houten, 2010, The Journal of Biological Chemistry.

Phenethyl isothiocyanate-induced apoptosis in PC-3 human prostate cancer cells is mediated by reactive oxygen species-dependent disruption of the mitochondrial membrane potential.

R. Dhir, Yan Zeng, Hui Xiao, 2006, Carcinogenesis.

Sulforaphane-induced G2/M Phase Cell Cycle Arrest Involves Checkpoint Kinase 2-mediated Phosphorylation of Cell Division Cycle 25C*

S. Srivastava, Shivendra V. Singh, K. Brown, 2004, Journal of Biological Chemistry.

Cancer chemoprevention with dietary isothiocyanates mature for clinical translational research.

Shivendra V. Singh, Kamayani Singh, 2012, Carcinogenesis.

Slow but Steady Progress in Cancer Chemoprevention with Phenethyl Isothiocyanate: Fulfilled Promises and Translational Challenges

Shivendra V. Singh, A. Bommareddy, A. Powolny, 2012 .

Phenethyl Isothiocyanate Inhibits Proliferation and Induces Apoptosis in Pancreatic Cancer Cells In Vitro and in a MIAPaca2 Xenograft Animal Model

R. Brand, Shivendra V. Singh, D. Whitcomb, 2014, Nutrition and cancer.

Differential Response of Normal (PrEC) and Cancerous Human Prostate Cells (PC-3) to Phenethyl Isothiocyanate-Mediated Changes in Expression of Antioxidant Defense Genes

Shivendra V. Singh, A. Powolny, 2010, Pharmaceutical Research.

17-DMAG dually inhibits Hsp90 and histone lysine demethylases in alveolar rhabdomyosarcoma

Taosheng Chen, A. Shelat, A. Davidoff, 2020, iScience.

Geldanamycin inhibits Jumonji histone lysine demethylase KDM4 and targets chimeric transcription factor PAX3-FOXO1

Taosheng Chen, A. Davidoff, Shivendra V. Singh, 2019, bioRxiv.

Phenethyl isothiocyanate inhibits angiogenesis in vitro and ex vivo.

Shivendra V. Singh, D. Xiao, 2007, Cancer research.

Novel mechanistic targets of Forkhead box Q1 transcription factor in human breast cancer cells

Shivendra V. Singh, Krishna B Singh, Eun-Ryeong Hahm, 2020, bioRxiv.

PABA/NO as an anticancer lead: analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity.

K. M. Davies, J. Deschamps, L. Jia, 2006, Journal of medicinal chemistry.

Benzyl Isothiocyanate Targets Mitochondrial Respiratory Chain to Trigger Reactive Oxygen Species-dependent Apoptosis in Human Breast Cancer Cells*

Shivendra V. Singh, D. Xiao, A. Powolny, 2008, Journal of Biological Chemistry.

Suppression of FOXQ1 in benzyl isothiocyanate-mediated inhibition of epithelial-mesenchymal transition in human breast cancer cells.

Shivendra V. Singh, A. Vogt, Su-Hyeong Kim, 2013, Carcinogenesis.

Super-resolution imaging reveals the evolution of higher-order chromatin folding in early carcinogenesis

Christopher A. Mela, Hongqiang Ma, Wei-Yan Jiang, 2020, Nature Communications.

Super-resolution imaging reveals the evolution of higher-order chromatin folding in early carcinogenesis

Christopher A. Mela, Hongqiang Ma, Wei-Yan Jiang, 2019, bioRxiv.

Withania somnifera root extract inhibits fatty acid synthesis in prostate cancer cells

Shivendra V. Singh, Krishna B Singh, B. Lokeshwar, 2020, Journal of traditional and complementary medicine.

RNA-seq reveals novel mechanistic targets of withaferin A in prostate cancer cellss.

Jacob Stewart-Ornstein, Shivendra V. Singh, Krishna B Singh, 2020, Carcinogenesis.

Reversal of the Warburg phenomenon in chemoprevention of prostate cancer by sulforaphane.

L. Foley, T. Hitchens, Shivendra V. Singh, 2019, Carcinogenesis.

Biomarkers of phenethyl isothiocyanate-mediated mammary cancer chemoprevention in a clinically relevant mouse model.

R. Dhir, Shivendra V. Singh, J. Beumer, 2012, Journal of the National Cancer Institute.

A novel metabolic function of Myc in regulation of fatty acid synthesis in prostate cancer

Shivendra V. Singh, Krishna B Singh, S. Wendell, 2020, Oncogene.

Elevated circulatory levels of leptin and resistin impair therapeutic efficacy of dacarbazine in melanoma under obese state

M. V. Vijayakumar, Shivendra V. Singh, M. Bhat, 2018, Cancer & Metabolism.

Molecular Targets and Mechanisms of Cancer Prevention and Treatment by Withaferin A, A Naturally Occurring Steroidal Lactone

Shivendra V. Singh, A. Vyas, 2013, The AAPS Journal.

Withaferin A-induced apoptosis in human breast cancer cells is associated with suppression of inhibitor of apoptosis family protein expression.

Shivendra V. Singh, Eun-Ryeong Hahm, 2012, Cancer letters.

Phenethyl isothiocyanate suppresses inhibitor of apoptosis family protein expression in prostate cancer cells in culture and in vivo

Shivendra V. Singh, Kozue Sakao, Eun-Ryeong Hahm, 2012, The Prostate.

Garlic Constituent Diallyl Trisulfide Suppresses X-linked Inhibitor of Apoptosis Protein in Prostate Cancer Cells in Culture and In Vivo

Shivendra V. Singh, A. Bommareddy, Su-Hyeong Kim, 2011, Cancer Prevention Research.

Benzyl Isothiocyanate Causes FoxO1-Mediated Autophagic Death in Human Breast Cancer Cells

Shivendra V. Singh, D. Xiao, A. Bommareddy, 2012, PloS one.

Transport functions and physiological significance of 76 kDa Ral-binding GTPase activating protein (RLIP76).

Shivendra V. Singh, Y. Awasthi, Rajendra K. Sharma, 2002, Acta biochimica Polonica.

Obesity induced rapid melanoma progression is reversed by orlistat treatment and dietary intervention: Role of adipokines

M. V. Vijayakumar, Shivendra V. Singh, M. Bhat, 2015, Molecular oncology.

Withaferin A inhibits expression of ataxia telangiectasia and Rad3‐related kinase and enhances sensitivity of human breast cancer cells to cisplatin

Shivendra V. Singh, Eun-Ryeong Hahm, Joomin Lee, 2019, Molecular Carcinogenesis.

llyl Trisulfide Inhibits Activation of Signal Transducer and ivator of Transcription 3 in Prostate Cancer Cells

Shivendra V. Singh, R. Chandra-Kuntal, 2010 .

Cell division cycle 25B phosphatase is essential for benzo(a)pyrene-7,8-Diol-9,10-epoxide induced neoplastic transformation.

S. Srivastava, J. Lazo, Shivendra V. Singh, 2007, Cancer research.

The carcinogen (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene induces Cdc25B expression in human bronchial and lung cancer cells.

J. Lazo, Shivendra V. Singh, T. Oguri, 2003, Cancer research.

Expression in Human Bronchial and Lung Cancer Cells 1

J. Lazo, Shivendra V. Singh, T. Oguri, 2003 .

Diallyl Trisulfide Inhibits Activation of Signal Transducer and Activator of Transcription 3 in Prostate Cancer Cells in Culture and In vivo

Shivendra V. Singh, K. Chandra-Kuntal, 2010, Cancer Prevention Research.

Disease Subtype–Independent Biomarkers of Breast Cancer Chemoprevention by the Ayurvedic Medicine Phytochemical Withaferin A

N. Davidson, Shivendra V. Singh, Ruchi Roy, 2017, Journal of the National Cancer Institute.

Mitochondrial dysfunction in cancer chemoprevention by phytochemicals from dietary and medicinal plants.

Shivendra V. Singh, Ruchi Roy, S. Pore, 2017, Seminars in cancer biology.

Mitochondrial Reactive Oxygen Species in Proapoptotic Effect of Promising Cancer Chemopreventive Phytochemicals

Shivendra V. Singh, A. Sehrawat, Anuradha Sehrawat, 2013 .

Cancer‐selective death of human breast cancer cells by leelamine is mediated by bax and bak activation

L. Rigatti, Shivendra V. Singh, S. Shiva, 2017, Molecular carcinogenesis.

Activation of a novel ataxia-telangiectasia mutated and Rad3 related/checkpoint kinase 1–dependent prometaphase checkpoint in cancer cells by diallyl trisulfide, a promising cancer chemopreventive constituent of processed garlic

Shivendra V. Singh, D. Xiao, A. Herman-Antosiewicz, 2007, Molecular Cancer Therapeutics.

Inhibition of human breast cancer xenograft growth by cruciferous vegetable constituent benzyl isothiocyanate

Shivendra V. Singh, D. Xiao, A. Bommareddy, 2010, Molecular carcinogenesis.

Molecular Mechanisms of Cancer Chemoprevention with Benzyl Isothiocyanate

Shivendra V. Singh, A. Sehrawat, Anuradha Sehrawat, 2013 .

Sodium butyrate induces DRP1-mediated mitochondrial fusion and apoptosis in human colorectal cancer cells.

R. Singh, Shivendra V. Singh, R. Kale, 2014, Mitochondrion.

Role of glutathione conjugate efflux in cellular protection against benzo[a]pyrene‐7,8‐diol‐9,10‐epoxide–induced DNA damage

Simon C Watkins, S. Srivastava, E. Schuetz, 2002, Molecular carcinogenesis.

Leelamine suppresses cMyc expression in prostate cancer cells in vitro and inhibits prostate carcinogenesis in vivo

Shivendra V. Singh, Krishna B Singh, Eun-Ryeong Hahm, 2021 .

Activity of melphalan in combination with the glutathione transferase inhibitor sulfasalazine

Bing-he Xu, M. Levitt, Shivendra V. Singh, 2004, Cancer Chemotherapy and Pharmacology.

Evaluation of Molecular and Ziehl-Neelsen stain for detection renal tuberculosis in urine sample

Usha, Shivendra V. Singh, Shailja Singh, 2018 .

Notch2 activation by benzyl isothiocyanate impedes its inhibitory effect on breast cancer cell migration

Shivendra V. Singh, Su-Hyeong Kim, A. Sehrawat, 2012, Breast Cancer Research and Treatment.

Weight control interventions improve therapeutic efficacy of dacarbazine in melanoma by reversing obesity-induced drug resistance

M. V. Vijayakumar, Shivendra V. Singh, M. Bhat, 2016, Cancer & Metabolism.

Role of lipid peroxidation in cellular responses to D,L-sulforaphane, a promising cancer chemopreventive agent.

R. Vatsyayan, Shivendra V. Singh, Y. Awasthi, 2010, Biochemistry.

Prevention of mammary carcinogenesis in MMTV-neu mice by cruciferous vegetable constituent benzyl isothiocyanate.

Shivendra V. Singh, W. Chambers, D. Potter, 2009, Cancer research.

Garlic constituent diallyl trisulfide prevents development of poorly differentiated prostate cancer and pulmonary metastasis multiplicity in TRAMP mice.

R. Dhir, Shivendra V. Singh, D. Xiao, 2008, Cancer Research.

Metabolic alterations in mammary cancer prevention by withaferin A in a clinically relevant mouse model.

Shivendra V. Singh, R. Bhargava, S. Shiva, 2013, Journal of the National Cancer Institute.

Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells

Shivendra V. Singh, Joomin Lee, A. Sehrawat, 2012, Breast Cancer Research and Treatment.

Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression

Shivendra V. Singh, M. Bhat, B. Chaube, 2015, Oncotarget.

A balanced level of profilin-1 promotes stemness and tumor-initiating potential of breast cancer cells

J. Condeelis, Shivendra V. Singh, P. Roy, 2017, Cell cycle.

Honokiol inhibits androgen receptor activity in prostate cancer cells

J. Arbiser, Shivendra V. Singh, M. Bonner, 2014, The Prostate.

Honokiol InhibitsAndrogen ReceptorActivity in Prostate Cancer Cells

J. Arbiser, Shivendra V. Singh, M. Bonner, 2022 .

DIAGNOSIS OF RENAL TUBERCULOSIS BY REAL-TIME POLYMERASE CHAIN REACTION IN RENAL BIOPSY SAMPLE

Usha, Shivendra V. Singh, S. Trivedi, 2017 .

Sulforaphane causes autophagy to inhibit release of cytochrome C and apoptosis in human prostate cancer cells.

Shivendra V. Singh, A. Herman-Antosiewicz, Daniel E. Johnson, 2006, Cancer research.

A Novel Sulforaphane-Regulated Gene Network in Suppression of Breast Cancer–Induced Osteolytic Bone Resorption

P. Kumta, Shivendra V. Singh, Boeun Lee, 2019, Molecular Cancer Therapeutics.

Crystal structure of shikimate kinase from Mycobacterium tuberculosis reveals the dynamic role of the LID domain in catalysis.

Yue Li, Honggao Yan, Shivendra V. Singh, 2002, Journal of molecular biology.

Protein kinase D3 (PKD3) contributes to prostate cancer cell growth and survival through a PKCepsilon/PKD3 pathway downstream of Akt and ERK 1/2.

Shivendra V. Singh, F. Deng, Q. Wang, 2008, Cancer research.

Chemopreventative potential of the cruciferous vegetable constituent phenethyl isothiocyanate in a mouse model of prostate cancer.

J. Nelson, Shivendra V. Singh, D. Normolle, 2011, Journal of the National Cancer Institute.

Critical role for reactive oxygen species in apoptosis induction and cell migration inhibition by diallyl trisulfide, a cancer chemopreventive component of garlic

Shivendra V. Singh, Joomin Lee, K. Chandra-Kuntal, 2013, Breast Cancer Research and Treatment.

p66Shc is indispensable for phenethyl isothiocyanate-induced apoptosis in human prostate cancer cells.

Shivendra V. Singh, D. Xiao, 2010, Cancer research.

Bim contributes to phenethyl isothiocyanate‐induced apoptosis in breast cancer cells

Shivendra V. Singh, Eun-Ryeong Hahm, 2012, Molecular carcinogenesis.

Role of mitogen‐activated protein kinases in phenethyl isothiocyanate‐induced apoptosis in human prostate cancer cells

Shivendra V. Singh, D. Xiao, Yong J. Lee, 2005, Molecular carcinogenesis.

Phenethyl Isothiocyanate Sensitizes Androgen-Independent Human Prostate Cancer Cells to Docetaxel-Induced Apoptosis In Vitro and In Vivo

Shivendra V. Singh, D. Xiao, 2010, Pharmaceutical Research.

Short‐form RON overexpression augments benzyl isothiocyanate‐induced apoptosis in human breast cancer cells

Shivendra V. Singh, A. Sehrawat, 2016, Molecular carcinogenesis.

In Vitro and In Vivo Effects of Phenethyl Isothiocyanate Treatment on Vimentin Protein Expression in Cancer Cells

Shivendra V. Singh, Kozue Sakao, Eun-Ryeong Hahm, 2013, Nutrition and cancer.

Notch Activation by Phenethyl Isothiocyanate Attenuates Its Inhibitory Effect on Prostate Cancer Cell Migration

Shivendra V. Singh, Kozue Sakao, Eun-Ryeong Hahm, 2011, PloS one.

Benzyl Isothiocyanate Inhibits Epithelial-Mesenchymal Transition in Cultured and Xenografted Human Breast Cancer Cells

Shivendra V. Singh, A. Sehrawat, Anuradha Sehrawat, 2011, Cancer Prevention Research.

d,l-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells

Shivendra V. Singh, Su-Hyeong Kim, 2009, Molecular Cancer Therapeutics.

Cell cycle arrest, apoptosis induction and inhibition of nuclear factor kappa B activation in anti-proliferative activity of benzyl isothiocyanate against human pancreatic cancer cells.

S. Srivastava, Shivendra V. Singh, 2004, Carcinogenesis.

AKT‐dependent sugar addiction by benzyl isothiocyanate in breast cancer cells

Shivendra V. Singh, Ruchi Roy, C. Anderson, 2019, Molecular carcinogenesis.

Functional relevance of d,l-sulforaphane-mediated induction of vimentin and plasminogen activator inhibitor-1 in human prostate cancer cells

Shivendra V. Singh, A. Vyas, 2014, European Journal of Nutrition.

CXCR 4 Is a Novel Target of Cancer Chemopreventative Isothiocyanates in Prostate Cancer Cells

Shivendra V. Singh, Rahul A Parikh, Kozue Sakao, 2015 .

Primary and secondary structural analyses of glutathione S-transferase π from human placenta

A. Kurosky, Shivendra V. Singh, Y. Awasthi, 1990 .

The role of polycomb group protein Bmi-1 and Notch4 in breast cancer stem cell inhibition by benzyl isothiocyanate

Shivendra V. Singh, Su-Hyeong Kim, 2015, Breast Cancer Research and Treatment.

Dietary Chemopreventative Benzyl Isothiocyanate Inhibits Breast Cancer Stem Cells In Vitro and In Vivo

Shivendra V. Singh, Su-Hyeong Kim, A. Sehrawat, 2013, Cancer Prevention Research.

Molecular Targets and Mechanisms of Cancer Prevention and Treatment by Withaferin A, A Naturally Occurring Steroidal Lactone

Shivendra V. Singh, A. Vyas, 2013, The AAPS Journal.

Immunochemical localization of glutathione S-transferases in rat lung

Shivendra V. Singh, Y. Awasthi, P. Moller, 2007, Lung.

Peptidyl‐prolyl cis/trans isomerase Pin1 regulates withaferin A‐mediated cell cycle arrest in human breast cancer cells

Shivendra V. Singh, Eun-Ryeong Hahm, Joomin Lee, 2018, Molecular carcinogenesis.

Metformin induced lactic acidosis impaired response of cancer cells towards paclitaxel and doxorubicin: Role of monocarboxylate transporter.

Shivendra V. Singh, M. Bhat, Ankita Deb, 2020, Biochimica et biophysica acta. Molecular basis of disease.

Withaferin A-mediated apoptosis in breast cancer cells is associated with alterations in mitochondrial dynamics.

Simon C Watkins, Shivendra V. Singh, C. S. St. Croix, 2019, Mitochondrion.

Broccoli-Derived Sulforaphane and Chemoprevention of Prostate Cancer: From Bench to Bedside

L. Appleman, Shivendra V. Singh, Rahul A Parikh, 2015, Current Pharmacology Reports.

Characterization of a human bladder cancer cell line selected for resistance to mitomycin C

Shivendra V. Singh, S. Singh, Vicram Gupta, 1994, International journal of cancer.

Targeting the spliceosome through RBM39 degradation results in exceptional responses in high-risk neuroblastoma models

Margaret A. Goralski, P. Thomas, A. Davidoff, 2021, Science advances.

of doxorubicin in solid tumor cells by methyl-β-cyclodextrin : Involvement of p 53 and Fas receptor ligand complex

Shivendra V. Singh, M. Bhat, B. Nair, 2015 .

Role of RLIP76 in lung cancer doxorubicin resistance: I. The ATPase activity of RLIP76 correlates with doxorubicin and 4-hydroxynonenal resistance in lung cancer cells.

Shivendra V. Singh, Y. Awasthi, Rajendra K. Sharma, 2003, International journal of oncology.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

Honokiol, a Constituent of Oriental Medicinal Herb Magnolia officinalis, Inhibits Growth of PC-3 Xenografts In vivo in Association with Apoptosis Induction

Shivendra V. Singh, Eun-Ryeong Hahm, J. Arlotti, 2008, Clinical Cancer Research.

Biochemical characterization of a mitomycin C‐resistant human bladder cancer cell line

Shivendra V. Singh, H. Zaren, H. Xia, 1996, International journal of cancer.

Elevated circulatory levels of leptin and resistin impair therapeutic efficacy of dacarbazine in melanoma under obese state

M. V. Vijayakumar, Shivendra V. Singh, M. Bhat, 2018, Cancer & metabolism.

Cloning and expression of a novel Mu class murine glutathione transferase isoenzyme.

Shivendra V. Singh, P. Zimniak, Jianxia Guo, 2002, The Biochemical journal.

Myoglobin induces mitochondrial fusion, thereby inhibiting breast cancer cell proliferation

Shivendra V. Singh, C. S. St. Croix, S. Shiva, 2019, The Journal of Biological Chemistry.

Modulation of cisplatin sensitivity and accumulation by interferon α‐2A in human squamous carcinoma cell lines

Shivendra V. Singh, H. Zaren, H. Xia, 1995, International journal of cancer.

Mechanism of cross‐resistance to cisplatin in a mitomycin C‐resistant human bladder cancer cell line

Bing-he Xu, Shivendra V. Singh, S. Specht, 1995, International journal of cancer.

Plumbagin-induced Apoptosis in Human Prostate Cancer Cells is Associated with Modulation of Cellular Redox Status and Generation of Reactive Oxygen Species

Shivendra V. Singh, A. Powolny, 2008, Pharmaceutical Research.

Mechanism of increased sensitivity to etoposide in a mitomycin C‐resisitant human bladder cancer cell line

Shivendra V. Singh, H. Zaren, H. Xia, 1997, International journal of cancer.

Critical Role of p 53 Upregulated Modulator of Apoptosis in Benzyl Isothiocyanate-Induced Apoptotic Cell Death

Shivendra V. Singh, Su-Hyeong Kim, Marie L Antony, 2012 .

The Oligostilbene Gnetin H Is a Novel Glycolysis Inhibitor That Regulates Thioredoxin Interacting Protein Expression and Synergizes with OXPHOS Inhibitor in Cancer Cells

P. Claudio, Shivendra V. Singh, A. Mouton, 2023, International journal of molecular sciences.

Genome-wide mapping of cancer dependency genes and genetic modifiers of chemotherapy in high-risk hepatoblastoma

S. Cairo, Taosheng Chen, J. Rehg, 2023, Nature communications.

Sulforaphane-Induced G 2 /M Phase Cell Cycle Arrest Involves Checkpoint Kinase 2 Mediated Phosphorylation of Cdc25C *

Baskaran, S. Srivastava, Shivendra V. Singh, 2004 .

Metabolic reprogramming of cancer cells by JMJD 6-mediated pre-mRNA splicing is associated 1 with therapeutic response to splicing inhibitor 2 3

Ji-Hoon Cho, D. Finkelstein, A. Davidoff, 2023 .

Honokiol causes G0-G1 phase cell cycle arrest in human prostate cancer cells in association with suppression of retinoblastoma protein level/phosphorylation and inhibition of E2F1 transcriptional activity

Shivendra V. Singh, Eun-Ryeong Hahm, 2007, Molecular Cancer Therapeutics.

Structural basis for catalytic differences between alpha class human glutathione transferases hGSTA1-1 and hGSTA2-2 for glutathione conjugation of environmental carcinogen benzo[a]pyrene-7,8-diol-9,10-epoxide.

S. Srivastava, X. Ji, S. Amin, 2004, Biochemistry.

Crystal structure of human glutathione S-transferase A3-3 and mechanistic implications for its high steroid isomerase activity.

Shivendra V. Singh, P. Zimniak, S. Pan, 2004, Biochemistry.

RNA‐seq reveals novel cancer‐selective and disease subtype‐independent mechanistic targets of withaferin A in human breast cancer cells

Shivendra V. Singh, Krishna B Singh, Eun-Ryeong Hahm, 2020, Molecular carcinogenesis.

Structure-based design of anticancer prodrug PABA/NO

X. Ji, Shivendra V. Singh, J. Saavedra, 2008, Drug design, development and therapy.

Mammary Cancer Chemoprevention by Withaferin A Is Accompanied by In Vivo Suppression of Self-Renewal of Cancer Stem Cells

Shivendra V. Singh, Su-Hyeong Kim, 2014, Cancer Prevention Research.

Binding of benzo(a)pyrene to rat lung glutathione S‐transferases in vivo

S. Srivastava, Shivendra V. Singh, Y. Awasthi, 1985, FEBS letters.

Withaferin A inhibits breast cancer‐induced osteoclast differentiation

Shivendra V. Singh, Eun-Ryeong Hahm, Su-Hyeong Kim, 2023, Molecular carcinogenesis.

Withaferin A inhibits experimental epithelial–mesenchymal transition in MCF‐10A cells and suppresses vimentin protein level in vivo in breast tumors

A. Marcus, Shivendra V. Singh, Eun-Ryeong Hahm, 2015, Molecular Carcinogenesis.

Withaferin A inhibits expression of ataxia telangiectasia and Rad3‐related kinase and enhances sensitivity of human breast cancer cells to cisplatin

Shivendra V. Singh, Eun-Ryeong Hahm, Joomin Lee, 2019, Molecular carcinogenesis.

Multitargeted prevention and therapy of cancer by diallyl trisulfide and related Allium vegetable-derived organosulfur compounds.

Shivendra V. Singh, A. Powolny, 2008, Cancer letters.

Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing is associated with therapeutic response to splicing inhibitor

Ji-Hoon Cho, D. Finkelstein, A. Davidoff, 2023, bioRxiv.

z-Guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, inhibits angiogenesis in vitro and in vivo

Shivendra V. Singh, D. Xiao, 2008, Molecular Cancer Therapeutics.

Mechanistic Targets of Diallyl Trisulfide in Human Breast Cancer Cells Identified by RNA-seq Analysis

R. Singh, Shivendra V. Singh, Eun-Ryeong Hahm, 2021, Journal of cancer prevention.

Forkhead Box Q1 is a novel regulator of autophagy in breast cancer cells

Shivendra V. Singh, Eun-Ryeong Hahm, Su-Hyeong Kim, 2023, Molecular carcinogenesis.

Location of the epoxide function determines specificity of the allelic variants of human glutathione transferase Pi toward benzo[c]chrysene diol epoxide isomers

S. Srivastava, S. Amin, D. Desai, 2000, FEBS letters.

Mechanism of differential catalytic efficiency of two polymorphic forms of human glutathione S-transferase P1-1 in the glutathione conjugation of carcinogenic diol epoxide of chrysene.

S. Srivastava, X. Ji, S. Srivastava, 1997, Archives of biochemistry and biophysics.