S. Zimmer

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Histone deacetylase inhibitors enhance paclitaxel-induced cell death in ovarian cancer cell lines independent of p53 status.

Nishan H Chobanian, V. L. Greenberg, J. Gass, 2004, Anticancer research.

A dominant-negative mutant of the platelet-derived growth factor A-chain increases survival of hamsters implanted intracerebrally with the highly invasive CxT24-neo3 glioblastoma cell

J. D. Reid, S. Zimmer, D. Kaetzel, 1998, Journal of Neuro-Oncology.

Transfection of mammalian cells with plasmid DNA by scrape loading and sonication loading.

S. Zimmer, M. Fechheimer, S G Zimmer, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Quantitative and qualitative differences in growth, invasion and lung colonization of an anaplastic and a papillary human thyroid cancer cell linein vitro andin vivo

V. L. Greenberg, S. Zimmer, K. Ain, 1996, Clinical & Experimental Metastasis.

Viscoelastic properties of transformed cells: role in tumor cell progression and metastasis formation.

S. Zimmer, S Zimmer, K. Ward, 1991, Biorheology.

Studies of the interactions between melatonin and 2 Hz, 0.3 mT PEMF on the proliferation and invasion of human breast cancer cells

S. Zimmer, K. Anderson, E. S. Leman, 2001, Bioelectromagnetics.

The novel silatecan 7-tert-butyldimethylsilyl-10-hydroxycamptothecin displays high lipophilicity, improved human blood stability, and potent anticancer activity.

Y. Pommier, S. Zimmer, G. Kohlhagen, 2000, Journal of medicinal chemistry.

Translation of ODC mRNA and polyamine transport are suppressed in ras-transformed CREF cells by depleting translation initiation factor 4E.

A. De Benedetti, S. Zimmer, J. Graff, 1997, Biochemical and biophysical research communications.

Cytokinesis is more rapid in Ha-T24-ras transfected rat embryo fibroblasts than in non-transfected control cells.

S. Zimmer, J. Boylan, J. Sisken, 1992, Cell motility and the cytoskeleton.

Hyperoxia alters the expression and phosphorylation of multiple factors regulating translation initiation.

S. Zimmer, A. Barchowsky, J. Shenberger, 2005, American journal of physiology. Lung cellular and molecular physiology.

Reduction of translation initiation factor 4E decreases the malignancy of ras ‐transformed cloned rat embryo fibroblasts

A. De Benedetti, S. Zimmer, J. Graff, 2006 .

Human Thyroid Carcinoma Papillary , Follicular , Hurthle ' s Cell , and Poorly Differentiated Distinct Patterns of E-Cadherin CpG Island Methylation in Updated

J. Herman, S. Baylin, W. Westra, 2006 .

The effects of group II phospholipase A2 on ras-induced metastasis.

S. Zimmer, T. Davis, E. Boghaert, 1997, Advances in experimental medicine and biology.

Decreasing the level of translation initiation factor 4E with antisense rna causes reversal of ras‐mediated transformation and tumorigenesis of cloned rat embryo fibroblasts

A. De Benedetti, R. Rhoads, S. Zimmer, 1993, International journal of cancer.

The effect of dibutyryl camp (dBcAMP) on morphological differentiation, growth and invasion in vitro of a hamster brain‐tumor cell line: A comparative study of dBcAMP effects in 2‐ and 3‐dimensional cultures

S. Zimmer, J. Simpson, E. Boghaert, 1991, International journal of cancer.

Oxidant-induced hypertrophy of A549 cells is accompanied by alterations in eukaryotic translation initiation factor 4E and 4E-binding protein-1.

S. Zimmer, J. Shenberger, M. H. Adams, 2002, American journal of respiratory cell and molecular biology.

Paclitaxel induces the phosphorylation of the eukaryotic translation initiation factor 4E-binding protein 1 through a Cdk1-dependent mechanism

V. L. Greenberg, S. Zimmer, 2005, Oncogene.

Changes in NF‐kappa B and ISGF3 DNA binding activities are responsible for differences in MHC and beta‐IFN gene expression in Ad5‐ versus Ad12‐transformed cells.

S. Zimmer, L. Babiss, U. Nielsch, 1991, The EMBO journal.

Spontaneous Progression of a Stage IV-S Human Neuroblastoma Cell Line Involves the Increased Expression of the Protooncogenes RAS and Eukaryotic Initiation Factor 4E

S. Zimmer, C. Fowler, C. Zimmer, 2000 .

Wild-type adenovirus type 5 transforming genes function as transdominant suppressors of oncogenesis in mutant adenovirus type 5 transformed rat embryo fibroblast cells.

Z. Su, H. Jiang, P. Fisher, 1993, Cancer research.

Induced expression of the endogenous beta interferon gene in adenovirus type 5-transformed rat fibroblasts

S. Zimmer, L. Babiss, R. Pine, 1992, Journal of virology.

NM23-H1 and NM23-H2 Repress Transcriptional Activities of Nuclease-hypersensitive Elements in the Platelet-derived Growth Factor-A Promoter*

B. Liu, S. Zimmer, Deqin Ma, 2002, The Journal of Biological Chemistry.

Susceptibility of Adenovirus 2-transformed rat cell lines to natural killer (NK) cells: direct correlation between NK resistance and in vivo tumorigenesis.

S. Zimmer, M. Sopori, P. H. Gallimore, 1984, Journal of immunology.

Opposing Actions of Thrombin and Protease Nexin‐1 on Amyloid β‐Peptide Toxicity and on Accumulation of Peroxides and Calcium in Hippocampal Neurons

M. Mattson, S. Zimmer, J. Fenton, 1995, Journal of neurochemistry.

Increasing N-CAM-mediated cell-cell adhesion does not reduce invasion of RSV-transformed WC5 rat cerebellar cells

S. Brady-Kalnay, S. Zimmer, E. Boghaert, 1993, Clinical & Experimental Metastasis.

TBJ murine neuroblastoma resists dibutyryl cyclic AMP-induced differentiation and effects on metalloproteinase secretion.

S. Zimmer, C. Fowler, C. Zimmer, 1998, Journal of pediatric surgery.

Role of the Ha-ras (RasH) oncogene in mediating progression of the tumor cell phenotype (review).

G. Duigou, P. Fisher, T. Roszman, 1990, Anticancer research.

Mechanisms of cisplatin (cis-diamminodichloroplatinum II)-induced cytotoxicity and genotoxicity in yeast.

J. Hazle, M. Hannan, S. Zimmer, 1984, Mutation research.

Pyrrol[1,4]benzodiazepine antibiotics. Proposed structures and characteristics of the in vitro deoxyribonucleic acid adducts of anthramycin, tomaymycin, sibiromycin, and neothramycins A and B.

D. J. Kaplan, S. Zimmer, G. L. Anderson, 1981, Biochemistry.

Induction and progression of the transformed phenotype in cloned rat embryo fibroblast cells: Studies employing type 5 adenovirus and wild‐type and mutant Ha‐ras oncogenes

P. Fisher, S. Zimmer, T. Y. Shih, 1992, Molecular carcinogenesis.

Metastasis of C1300 and TBJ murine neuroblastomas correlates with expression of matrix metalloproteinases.

S. Zimmer, E. Boghaert, C. Fowler, 1995, Cancer letters.

DNA-dependent RNA polymerase from Pseudomonas BAL-31. I. Purification and properties of the enzyme.

S. Zimmer, R. Millette, 1975, Biochemistry.

Novel A,B,E-ring-modified camptothecins displaying high lipophilicity and markedly improved human blood stabilities.

S. Zimmer, T. Burke, D. Curran, 1999, Journal of medicinal chemistry.

Reversibility of progression of the transformed phenotype in Ad5-transformed rat embryo cells.

P. Fisher, S. Zimmer, L. Babiss, 1985, Science.

Translational control and metastatic progression: Enhanced activity of the mRNA cap-binding protein eIF-4E selectively enhances translation of metastasis-related mRNAs

S. Zimmer, J. Graff, 2004, Clinical & Experimental Metastasis.

Distinct patterns of E-cadherin CpG island methylation in papillary, follicular, Hurthle's cell, and poorly differentiated human thyroid carcinoma.

J. Herman, S. Baylin, W. Westra, 1998, Cancer research.

Invasion by WC5 rat cerebellar cells is independent of RSV‐induced changes in growth and adhesion

D. Soll, S. Brady-Kalnay, S. Zimmer, 1991, International journal of cancer.

The involvement of a stress-activated pathway in equine influenza virus-mediated apoptosis.

S. Zimmer, Z. Lu, Q. Dong, 2001, Virology.

Mutations in the E1a gene of type 5 adenovirus result in oncogenic transformation of fischer rat embryo cells

G. Duigou, P. Fisher, S. Zimmer, 1987, Journal of cellular biochemistry.

The influence of the presence of adenovirus 5 E1a and E1b sequences on the pathology of rat embryonic fibroblasts transfected with activated c-Ha-ras and v-ras

S. Zimmer, E. Boghaert, V. Austin, 1991, Clinical and Experimental Metastasis.

A link between ras and metastatic behavior of tumor cells: ras induces CD44 promoter activity and leads to low-level expression of metastasis-specific variants of CD44 in CREF cells.

P. Herrlich, M. Zöller, S. Zimmer, 1993, Cancer research.

Translational control of malignancy: the mRNA cap-binding protein, eIF-4E, as a central regulator of tumor formation, growth, invasion and metastasis.

S. Zimmer, J. Graff, A. DeBenedetti, 2000, Anticancer research.

In vitro studies of deformation and adhesion properties of transformed cells

S. Zimmer, K. Anderson, Wen-I Li, 1991, Cell Biophysics.

Transfection of normal and transformed hamster cerebral cortex glial cells with activated c-H-ras-1 results in the acquisition of a diffusely invasive phenotype.

S. Zimmer, J. Fetherston, J. Cotton, 1989, Oncogene research.

Mutations in the E1a gene of adenovirus type 5 alter the tumorigenic properties of transformed cloned rat embryo fibroblast cells.

P. Fisher, S. Zimmer, L. Babiss, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Effect of methyl methanesulfonate on type 5 adenovirus DNA integration and the phenotypic properties of cold-sensitive type 5 adenovirus-transformed cloned rat embryo fibroblast cells.

G. Duigou, P. Fisher, S. Zimmer, 1988, Cancer research.

Histone deacetylase inhibitors promote apoptosis and differential cell cycle arrest in anaplastic thyroid cancer cells.

V. L. Greenberg, S. Zimmer, J. Cogswell, 2001, Thyroid : official journal of the American Thyroid Association.

Butyrate alters the expression and activity of cell cycle components in anaplastic thyroid carcinoma cells.

V. L. Greenberg, S. Zimmer, J. Williams, 2001, Thyroid : official journal of the American Thyroid Association.

Invasiveness in primary intracranial tumors: Part 2. Studies with scanning electron microscopy of cell surface alterations associated with invasiveness.

S. Zimmer, J. Walsh, J. Oeltgen, 1987, Neurosurgery.

Invasiveness in primary intracranial tumors: Part 1. An experimental model using cloned SV40 virus-produced hamster brain tumors.

W. Markesbery, S. Zimmer, J. Walsh, 1986, Neurosurgery.

Inhibition of collagenolytic activity relates to quantitative reduction of invasionin vitro in a c-Ha-ras transfected glial cell line

T. Vanaman, S. Zimmer, D. Grobelny, 2005, Journal of Neuro-Oncology.

In vitro and in vivo histone deacetylase inhibitor therapy with suberoylanilide hydroxamic acid (SAHA) and paclitaxel in ovarian cancer.

V. L. Greenberg, J. van Nagell, S. Zimmer, 2007, Gynecologic oncology.

Quantitative and qualitative differences in growth, invasion and lung colonization of an anaplastic and a papillary human thyroid cancer cell line in vitro and in vivo.

V. L. Greenberg, S. Zimmer, K. Ain, 1996, Clinical & experimental metastasis.

Elevated expression of eIF4E and FGF-2 isoforms during vascularization of breast carcinomas

Benjamin D. L. Li, S. Zimmer, F. Abreo, 1997, Oncogene.

The Emerging Role for the mRNA Cap-Binding Protein, EIF-4E, in Metastatic Progression

S. Zimmer, J. Graff, 2002 .

The metastasis suppressor NME1 regulates expression of genes linked to metastasis and patient outcome in melanoma and breast carcinoma.

E. Blalock, S. Zimmer, Deqin Ma, 2014, Cancer genomics & proteomics.

Role of viruses in the induction of primary intracranial tumors.

S. Zimmer, M. Perdue, J. Walsh, 1982, Neurosurgery.

DNA-dependent RNA polymerase from Pseudomonas BAL-31. II. Transcription of the allomorphic forms of bacteriophage PM2 DNA.

S. Zimmer, R. Millette, 1975, Biochemistry.

Synthesis and evaluation of a novel E-ring modified alpha-hydroxy keto ether analogue of camptothecin.

S. Zimmer, T. Burke, D. Curran, 2002, Bioorganic & medicinal chemistry.

The highly lipophilic DNA topoisomerase I inhibitor DB-67 displays elevated lactone levels in human blood and potent anticancer activity.

J. Zhang, S. Zimmer, T. Burke, 2001, Journal of controlled release : official journal of the Controlled Release Society.

It's about time: scheduling alters effect of histone deacetylase inhibitors on camptothecin-treated cells.

S. Zimmer, Robert L Bevins, Stephen G Zimmer, 2005, Cancer research.

Adhesion of nonmetastatic and highly metastatic breast cancer cells to endothelial cells exposed to shear stress.

S. Zimmer, K. Anderson, K W Anderson, 1999, Biorheology.

Defining the critical gene expression changes associated with expression and suppression of the tumorigenic and metastatic phenotype in Ha-ras-transformed cloned rat embryo fibroblast cells.

Z. Su, P. Fisher, S. Zimmer, 1993, Oncogene.

Suberoylanilide hydroxamic acid (SAHA) potentiates paclitaxel-induced apoptosis in ovarian cancer cell lines.

V. L. Greenberg, C. Desimone, J. van Nagell, 2010, Gynecologic oncology.

Detachment of transformed cells

P. Fisher, S. Zimmer, K. Anderson, 1995, Cell Biophysics.

Role of metastatic potential in the adhesion of human breast cancer cells to endothelial monolayers.

S. Zimmer, K. Anderson, M. Moss, 2000, Anticancer research.

Transcriptional switching model for the regulation of tumorigenesis and metastasis by the ha-ras oncogene - transcriptional changes in the ha-ras tumor-suppressor gene lysyl oxidase.

Z. Su, P. Fisher, S. Zimmer, 1995, International journal of oncology.

Invasion in vitro of malignant hamster brain tumor cells is influenced by the number of cells and the mode of malignant progression.

S. Zimmer, J. Simpson, E. Boghaert, 1992, Invasion & metastasis.

The effects of shear stress and metastatic phenotype on the detachment of transformed cells.

S. Zimmer, K. Ward, M. Hosseinipour, 1991, Biorheology.

Analysis of early adenovirus 2 RNA using Eco R-R1 viral DNA fragments

E. Craig, S. Zimmer, H. Raskas, 1975, Journal of virology.

CD44 in Normal Differentation and Tumor Progression

P. Herrlich, M. Zöller, K. Heider, 1993 .

Ras transformation of cloned rat embryo fibroblasts results in increased rates of protein synthesis and phosphorylation of eukaryotic initiation factor 4E.

R. Rhoads, S. Zimmer, C. Rinker-Schaeffer, 1992, The Journal of biological chemistry.

Use of a viral probe to study recombinational exchanges in mammalian cells.

G. Duigou, S. Zimmer, 1983, Progress in nucleic acid research and molecular biology.