Z. Miao

发表

DNA damage, c-myc suppression and apoptosis induced by the novel topoisomerase II inhibitor, salvicine, in human breast cancer MCF-7 cells

M. Huang, Min Huang, Hua-Rui Lu, 2005, Cancer Chemotherapy and Pharmacology.

A data-driven drug repositioning framework discovered a potential therapeutic agent targeting COVID-19

Jianyang Zeng, Ligong Chen, Z. Miao, 2020, bioRxiv.

Fragment-based drug discovery of 2-thiazolidinones as inhibitors of the histone reader BRD4 bromodomain.

Yechun Xu, Lele Zhao, Z. Miao, 2013, Journal of medicinal chemistry.

Emerging cancer therapeutic opportunities target DNA-repair systems.

Ling-hua Meng, Z. Miao, Jian Ding, 2006, Trends in pharmacological sciences.

Three‐Component, One‐Pot Sequential Synthesis of Tetracyclic Pyrido[2′,1′:2,3]imidazo[5,1‐a]isoquinolinium Compounds as Potent Anticancer Agents

Weiqi Wang, Z. Miao, Jing-kang Shen, 2012 .

Polymerase independent repression of FoxO1 transcription by sequence-specific PARP1 binding to FoxO1 promoter

Z. Miao, Ying-qing Wang, Yu-Nan Tian, 2020, Cell Death & Disease.

Natural product-based design, synthesis and biological evaluation of anthra[2,1-d]thiazole-6,11-dione derivatives from rhein as novel antitumour agents.

Z. Miao, Y. Liang, Zhizhou Yue, 2014, European journal of medicinal chemistry.

Discovery of MTR-106 as a highly potent G-quadruplex stabilizer for treating BRCA-deficient cancers

Z. Miao, B. Xiong, Jing-kang Shen, 2021, Investigational New Drugs.

Poly(ADP-ribose) polymerase inhibitors as promising cancer therapeutics

Z. Miao, Chun-hao Yang, Jin-Xue He, 2010, Acta Pharmacologica Sinica.

Identification of 2-substituted pyrrolo[1,2-b]pyridazine derivatives as new PARP-1 inhibitors.

Yi Chen, Z. Miao, Jian Ding, 2020, Bioorganic & medicinal chemistry letters.

Synthesis of OSW-1 analogues and a dimer and their antitumor activities.

Z. Miao, X. Ma, Y. Hui, 2001, Bioorganic & medicinal chemistry letters.

Rare new bicyclic cembranoid ethers and a novel trihydroxy prenylated guaiane from the Xisha soft coral Lobophytum sp.

Z. Miao, Yue‐Wei Guo, A. Hernández Daranas, 2020, Bioorganic chemistry.

Multi-drug-resistant cells enriched from chronic myeloid leukemia cells by Doxorubicin possess tumor-initiating-cell properties.

Z. Miao, Ke Wang, H. Xin, 2013, Journal of pharmacological sciences.

Triptolide: structural modifications, structure-activity relationships, bioactivities, clinical development and mechanisms.

Z. Miao, Jian Ding, Ya-xi Yang, 2012, Natural product reports.

Design and synthesis of novel C14-hydroxyl substituted triptolide derivatives as potential selective antitumor agents.

Z. Miao, Jian Ding, Lin-jiang Tong, 2009, Journal of medicinal chemistry.

Newly discovered angiogenesis inhibitors and their mechanisms of action

Z. Miao, Jian Ding, Jian-ming Feng, 2012, Acta Pharmacologica Sinica.

Increased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolide

Yi Chen, Z. Miao, Jian Ding, 2010, Molecular Cancer.

Tanshinone I inhibits tumor angiogenesis by reducing STAT3 phosphorylation at TYR705 and hypoxia-induced HIF-1α accumulation in both endothelial and tumor cells

Z. Miao, Ying-qing Wang, Jia-xin Li, 2015, Oncotarget.

Discovery, mechanism and metabolism studies of 2,3-difluorophenyl-linker-containing PARP1 inhibitors with enhanced in vivo efficacy for cancer therapy.

Yun Tang, Yi Chen, Z. Miao, 2017, European journal of medicinal chemistry.

The inhibition of metastasis and growth of breast cancer by blocking the NF-κB signaling pathway using bioreducible PEI-based/p65 shRNA complex nanoparticles.

Z. Miao, Chunying Chen, Yaping Li, 2013, Biomaterials.

Discovery of novel 2-phenyl-imidazo[1,2-a]pyridine analogues targeting tubulin polymerization as antiproliferative agents.

Z. Miao, Jing-kang Shen, T. Meng, 2016, European journal of medicinal chemistry.

The Telomeric Protein TRF2 Is Critical for the Protection of A549 Cells from Both Telomere Erosion and DNA Double-Strand Breaks Driven by Salvicine

Z. Miao, Jian Ding, Yong-Wei Zhang, 2008, Molecular Pharmacology.

Echinoside A, a new marine-derived anticancer saponin, targets topoisomerase2alpha by unique interference with its DNA binding and catalytic cycle.

Z. Miao, Z. Chen, M. Gui, 2010, Annals of oncology : official journal of the European Society for Medical Oncology.

MCL-1 Degradation Mediated by JNK Activation via MEKK1/TAK1-MKK4 Contributes to Anticancer Activity of New Tubulin Inhibitor MT189

Yi Chen, Z. Miao, Jian Ding, 2014, Molecular Cancer Therapeutics.

Marine-Derived Angiogenesis Inhibitors for Cancer Therapy

Z. Miao, Ying-qing Wang, Ying-Qing Wang, 2013, Marine drugs.

Total synthesis of novel D-ring-modified triptolide analogues: structure-cytotoxic activity relationship studies on the D-ring of triptolide.

Z. Miao, Yuanchao Li, Hui-jin Feng, 2011, Organic & biomolecular chemistry.

Synthesis and biological evaluation of novel triptolide analogues for anticancer activity.

Z. Miao, Jian Ding, Yuanchao Li, 2010, Bioorganic & medicinal chemistry letters.

MFTZ-1, an actinomycetes subspecies–derived antitumor macrolide, functions as a novel topoisomerase II poison

Yi Chen, Hong Zhu, Z. Miao, 2007, Molecular Cancer Therapeutics.

Cytotoxicity, apoptosis induction and downregulation of MDR‐1 expression by the anti‐topoisomerase II agent, salvicine, in multidrug‐resistant tumor cells

Z. Miao, Jian Ding, Yi-xiang Zhang, 2003, International journal of cancer.

SOMCL-19-133, a novel, selective, and orally available inhibitor of NEDD8-activating enzyme (NAE) for cancer therapy

Z. Miao, Shan-shan Song, Xubin Bao, 2022, Neoplasia.

Therapeutics , Targets , and Chemical Biology Natural Product Triptolide Mediates Cancer Cell Death by Triggering CDK 7-Dependent Degradation of RNA Polymerase II

G. Capranico, Z. Miao, Jian Ding, 2012 .

A new BET inhibitor, 171, inhibits tumor growth through cell proliferation inhibition more than apoptosis induction

Z. Miao, B. Xiong, Jing-kang Shen, 2019, Investigational New Drugs.

Novel liver-specific cholic acid-cytarabine conjugates with potent antitumor activities: Synthesis and biological characterization

Z. Miao, Jing-kang Shen, Dan-qi Chen, 2011, Acta Pharmacologica Sinica.

Characterization of salvicine‐resistant lung adenocarcinoma A549/SAL cell line

Z. Miao, Jian Ding, Lin-jiang Tong, 2004, International journal of cancer.

Transcription factor c-Jun activation represses mdr-1 gene expression.

Z. Miao, Jian Ding, 2003, Cancer research.

Novel dihydroisoxazoline-alkyl carbon chain hybrid artemisinin analogues (artemalogs): synthesis and antitumor activities

Z. Miao, Xiaohua Liu, Gang Liu, 2016 .

Novel spirobicyclic artemisinin analogues (artemalogues): Synthesis and antitumor activities.

Z. Miao, Gang Liu, A. Zhang, 2015, European journal of medicinal chemistry.

Novel indenoisoquinolines NSC 725776 and NSC 724998 produce persistent topoisomerase I cleavage complexes and overcome multidrug resistance.

Y. Pommier, A. Robles, Z. Miao, 2007, Cancer research.

Flabellipparicine, a Flabelliformide-Apparicine-Type Bisindole Alkaloid from Tabernaemontana divaricata.

Ariel M. Sarotti, Z. Miao, A. Mándi, 2018, Journal of natural products.

Proteasome-dependent degradation of Chk1 kinase induced by the topoisomerase II inhibitor R16 contributes to its anticancer activity

Hong Zhu, Z. Miao, Jian Ding, 2008, Cancer biology & therapy.

Design, synthesis and pharmacological evaluation of new PARP1 inhibitors by merging pharmacophores of olaparib and the natural product alantolactone.

Z. Miao, L. Jia, Shan-shan Song, 2022, European journal of medicinal chemistry.

R16, a novel amonafide analogue, induces apoptosis and G2-M arrest via poisoning topoisomerase II

M. Huang, Min Huang, Yi Chen, 2007, Molecular Cancer Therapeutics.

Triptolide Induces Cell Killing in Multidrug-Resistant Tumor Cells via CDK7/RPB1 Rather than XPB or p44

Z. Miao, Hu Zhou, Shan-shan Song, 2016, Molecular Cancer Therapeutics.

Natural product triptolide mediates cancer cell death by triggering CDK7-dependent degradation of RNA polymerase II.

G. Capranico, Z. Miao, Jian Ding, 2012, Cancer research.

Inhibition of the BET family reduces its new target gene IDO1 expression and the production of l-kynurenine

Z. Miao, B. Xiong, Jing-kang Shen, 2019, Cell Death & Disease.

Pseudolaric acid B-driven phosphorylation of c-Jun impairs its role in stabilizing HIF-1alpha: a novel function-converter model

Z. Miao, Jian Ding, Sheng Yang, 2012, Journal of Molecular Medicine.

New tanshinone I derivatives S222 and S439 similarly inhibit topoisomerase I/II but reveal different p53‐dependency in inducing G2/M arrest and apoptosis

Z. Miao, Ao Zhang, Shan-shan Song, 2018, Biochemical pharmacology.

Reactive oxygen species contribute to cell killing and p-glycoprotein downregulation by salvicine in multidrug resistant K562/A02 cells

Jin-jian Lu, Z. Miao, Jian Ding, 2007, Cancer biology & therapy.

Chk1 and Chk2 are differentially involved in homologous recombination repair and cell cycle arrest in response to DNA double-strand breaks induced by camptothecins

W. Lu, Min Huang, Hong Zhu, 2008, Molecular Cancer Therapeutics.

Naphthalimides induce G(2) arrest through the ATM-activated Chk2-executed pathway in HCT116 cells.

M. Huang, Jin-jian Lu, Min Huang, 2009, Neoplasia.

Design, synthesis and biological evaluation of substituted 11H-benzo[a]carbazole-5-carboxamides as novel antitumor agents.

Yi Chen, Z. Miao, Jian Ding, 2011, European journal of medicinal chemistry.

Bisindenoisoquinoline NSC 727357, a DNA intercalator and topoisomerase inhibitor with antitumor activity

Y. Pommier, S. Holbeck, Z. Miao, 2006 .

Poly(ADP-ribose)polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials.

Na Ye, Yi Chen, Z. Miao, 2017, Cancer letters.

Acquired resistance of phosphatase and tensin homolog‐deficient cells to poly(ADP‐ribose) polymerase inhibitor and Ara‐C mediated by 53BP1 loss and SAMHD1 overexpression

Z. Miao, Yu-Nan Tian, Hua-Dong Chen, 2018, Cancer science.

Rh(III)-catalyzed redox-neutral C-H activation of pyrazolones: an economical approach for the synthesis of N-substituted indoles.

Z. Miao, Wei Li, Z. Fan, 2015, Organic letters.

Multi-omics characterization of WNT pathway reactivation to ameliorate BET inhibitor resistance in liver cancer cells.

Xin Hu, Jingkang Shen, Z. Miao, 2021, Genomics.

An Update on Poly(ADP-ribose)polymerase-1 (PARP-1) Inhibitors: Opportunities and Challenges in Cancer Therapy.

Z. Miao, Guangfu Yang, Pingyuan Wang, 2016, Journal of medicinal chemistry.

Cascade synthesis of novel functionalized pyridine-fused coumarins in aqueous medium

Z. Miao, Chunhao Yang, Jianyang Chen, 2014 .

Discovery of a series of dihydroquinoxalin-2(1H)-ones as selective BET inhibitors from a dual PLK1-BRD4 inhibitor.

Z. Miao, B. Xiong, Jing-kang Shen, 2017, European journal of medicinal chemistry.

Structural evidence for the facile chelate-ring opening reactions of novel platinum(II)‒pyridine carboxamide complexes

Z. Miao, Jian Ding, X. You, 2002 .

Design, synthesis and biological evaluation of substituted 11H-benzo[a]carbazole-5-carboxamides as novel antitumor agents.

Yi Chen, Z. Miao, Jian Ding, 2011, European journal of medicinal chemistry.

Rapid access to α-carbolines via a one-pot tandem reaction of α,β-unsaturated ketones with 2-nitrophenylacetonitrile and the anti-proliferative activities of the products.

Z. Miao, Xiaofei Zhang, Chunhao Yang, 2014, Organic & biomolecular chemistry.

Structural and stereochemical studies of alpha-methylene-gamma-lactone-bearing cembrane diterpenoids from a south china sea soft coral Lobophytum crassum.

Z. Miao, Jian Ding, T. Kurtán, 2008, Journal of natural products.

One Pot and Metal-Free Approach to 3-(2-Hydroxybenzoyl)-1-aza-anthraquinones

Z. Miao, Jiaqi Yuan, Xiaofei Zhang, 2019, Molecules.

Cascade Synthesis of Novel Functionalized Pyridine‐Fused Coumarins in Aqueous Medium.

Z. Miao, Chunhao Yang, Jianyang Chen, 2014 .

InBr3-mediated one-pot synthesis of 2-(polyhydroxylatedalkyl)-N-aryl-/-alkylpyrroles from 1,2-cyclopropa-3-pyranone and amines.

Z. Miao, Guangfu Yang, Pingyuan Wang, 2013, Organic letters.

Design, synthesis, and anticancer activities of new compounds bearing the quinone–pyran–lactone tricyclic pharmacophore

Z. Miao, Meining Wang, A. Zhang, 2015 .

A new bis-γ-pyrone polypropionate of onchidiol family from marine pulmonate mollusk Onchidium sp

Z. Miao, M. Gavagnin, E. Mollo, 2019, Natural product research.

Three New Cytotoxic Monoterpenoid Bisindole Alkaloids from Tabernaemontana bufalina

Z. Miao, S. Cao, G. Qiu, 2018, Planta Medica.

Pseudolaric Acid B Inhibits Angiogenesis and Reduces Hypoxia-Inducible Factor 1α by Promoting Proteasome-Mediated Degradation

Z. Miao, Jian Ding, J. Yue, 2004, Clinical Cancer Research.

Metal-free quinolylation of the primary amino groups of amino acid derivatives and peptides with dihydrooxazolo[3,2-a]quinoliniums

Weiliang Zhu, Kaixian Chen, Z. Miao, 2019, Green Chemistry.

Eucalyptals A-C with a new skeleton isolated from Eucalyptus globulus.

Z. Miao, C. Fan, J. Yue, 2007, Organic letters.

Advances in Cancer Chemotherapeutic Drug Research in China

Kaixian Chen, Xiao-min Luo, Z. Miao, 2012, Recent Advances in Cancer Research and Therapy.

Inulin based glutathione-responsive delivery system for colon cancer treatment.

Z. Miao, J. Duan, Dongdong Wang, 2018, International journal of biological macromolecules.

New cytotoxic ergostane-type sterols from the Chinese soft coral Sinularia sp.

Z. Miao, Cheng-Shi Jiang, Yue‐Wei Guo, 2019, Steroids.

Chimmitecan, a Novel 9-Substituted Camptothecin, with Improved Anticancer Pharmacologic Profiles In vitro and In vivo

Jian Zhang, Min Huang, Yi Chen, 2007, Clinical Cancer Research.

Bisindenoisoquinoline Bis-1,3-{(5,6-dihydro-5,11-diketo-11H-indeno[1,2-c]isoquinoline)-6-propylamino}propane bis(trifluoroacetate) (NSC 727357), a DNA Intercalator and Topoisomerase Inhibitor with Antitumor Activity

Y. Pommier, S. Holbeck, Z. Miao, 2006, Molecular Pharmacology.

Chemical Components of Dendrobium chrysotoxum

Z. Miao, Jun Zhou, Weiwei Fan, 2012 .

Reactive Oxygen Species Elicit Apoptosis by Concurrently Disrupting Topoisomerase II and DNA-Dependent Protein Kinase

Min Huang, Yi Chen, Hua-Rui Lu, 2005, Molecular Pharmacology.

Novel bivalent BET inhibitor N2817 exhibits potent anticancer activity and inhibits TAF1.

Z. Miao, B. Xiong, Qian Wu, 2021, Biochemical pharmacology.

Aphanamolide A, a new limonoid from Aphanamixis polystachya.

Z. Miao, J. Yue, S. Liao, 2011, Organic letters.

Cytotoxic dihydroagarofuranoid sesquiterpenes from the seeds of Celastrus orbiculatus.

Z. Miao, Zehong Miao, Yingdong Zhu, 2008, Journal of natural products.

Lagerindicine, a New Pyrrole Alkaloid Isolated from the Flowers of Lagerstroemia indica Linnaeus

Yi Chen, Z. Miao, Yue‐Wei Guo, 2020, Natural Products and Bioprospecting.

Four new cembranoids from the Chinese soft coral Sinularia sp. and their anti-Aβ aggregation activities.

Z. Miao, Cheng-Shi Jiang, Yue‐Wei Guo, 2019, Fitoterapia.

Bioactive polyoxygenated cembranoids from a novel Hainan chemotype of the soft coral Sinularia flexibilis.

Hong Wang, Z. Miao, Heng Li, 2019, Bioorganic & medicinal chemistry letters.

Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance

Yi Chen, Z. Miao, Jian Ding, 2023, EMBO molecular medicine.

Palmarumycins BG1-BG7 and preussomerin BG1: establishment of their absolute configurations using theoretical calculations of electronic circular dichroism spectra.

I. Komáromi, Z. Miao, Jian Ding, 2011, The Journal of organic chemistry.

An integrative drug repositioning framework discovered a potential therapeutic agent targeting COVID-19

Jianyang Zeng, Ligong Chen, Z. Miao, 2021, Signal Transduction and Targeted Therapy.

Structural Modification of Natural Product Tanshinone I Leading to Discovery of Novel Nitrogen-Enriched Derivatives with Enhanced Anticancer Profile and Improved Drug-like Properties.

Z. Miao, A. Zhang, C. Ding, 2018, Journal of medicinal chemistry.

4-nitroquinoline-1-oxide induces the formation of cellular topoisomerase I-DNA cleavage complexes.

K. Kohn, Y. Pommier, Z. Miao, 2006, Cancer research.

Synthesis of steroidal glycosides bearing the disaccharide moiety of OSW-1 and their antitumor activities.

Z. Miao, Y. Hui, B. Yu, 2001, Carbohydrate research.

Tanshinone-1 induces tumor cell killing, enhanced by inhibition of secondary activation of signaling networks

Y. Chen, Z. Miao, Jian Ding, 2013, Cell Death and Disease.

Actinomycin D inhibiting K562 cell apoptosis elicited by salvicine but not decreasing its cytotoxicity.

Z. Miao, Jian Ding, Lin-jiang Tong, 2003, Acta pharmacologica Sinica.

MT7, a novel compound from a combinatorial library, arrests mitosis via inhibiting the polymerization of microtubules

Jingkang Shen, Z. Miao, Jian Ding, 2010, Investigational New Drugs.

Combining 53BP1 with BRCA1 as a biomarker to predict the sensitivity of poly(ADP-ribose) polymerase (PARP) inhibitors

Yi Chen, Z. Miao, Jian Ding, 2017, Acta Pharmacologica Sinica.

Defective Mre11-dependent Activation of Chk2 by Ataxia Telangiectasia Mutated in Colorectal Carcinoma Cells in Response to Replication-dependent DNA Double Strand Breaks*

Y. Pommier, Z. Miao, O. Sordet, 2006, Journal of Biological Chemistry.

Endogenous γ-H2AX-ATM-Chk2 Checkpoint Activation in Bloom's Syndrome Helicase–Deficient Cells Is Related to DNA Replication Arrested Forks

Y. Pommier, B. Saccà, I. Hickson, 2007, Molecular Cancer Research.

TNKS inhibitors potentiate proliferative inhibition of BET inhibitors via reducing β-Catenin in colorectal cancer cells.

Z. Miao, Qian Wu, Xubin Bao, 2022, American journal of cancer research.

Characterization of the conversion between CD133+ and CD133- cells in colon cancer SW620 cell line

Yi Chen, Z. Miao, Jian Ding, 2012, Cancer biology & therapy.

Nonclassic functions of human topoisomerase I: genome-wide and pharmacologic analyses.

J. Weinstein, Y. Pommier, E. Kawasaki, 2007, Cancer research.

Repair of topoisomerase I-mediated DNA damage.

Y. Pommier, Z. Miao, C. Redon, 2006, Progress in nucleic acid research and molecular biology.

Dihydroindenoisoquinolines function as prodrugs of indenoisoquinolines.

Y. Pommier, Z. Miao, Smitha Antony, 2005, Bioorganic & medicinal chemistry letters.

Telomerase inhibition is a specific early event in salvicine-treated human lung adenocarcinoma A549 cells.

Z. Miao, Jian Ding, Wei-jun Liu, 2004, Biochemical and biophysical research communications.

hTERT-targeted RNA interference inhibits tumorigenicity and motility of HCT116 cells

Z. Miao, Jian Ding, Yong-Wei Zhang, 2008, Cancer biology & therapy.

Repeated treatments of Capan-1 cells with PARP1 and Chk1 inhibitors promote drug resistance, migration and invasion

Z. Miao, Hua-Dong Chen, Meng-Zhu Li, 2022, Cancer biology & therapy.

c-Jun protects hypoxia-inducible factor-1alpha from degradation via its oxygen-dependent degradation domain in a nontranscriptional manner.

Z. Miao, Jian Ding, Bing Yu, 2009, Cancer research.

Structure-based optimization of a series of selective BET inhibitors containing aniline or indoline groups.

Z. Miao, Jian Li, B. Xiong, 2018, European journal of medicinal chemistry.

Design, synthesis, and biological evaluation of a series of benzo[de][1,7]naphthyridin-7(8H)-ones bearing a functionalized longer chain appendage as novel PARP1 inhibitors.

Qiufeng Liu, Shan-Shan Song, Yechun Xu, 2013, Journal of medicinal chemistry.

Antiangiogenic activity of 11,11'-dideoxyverticillin, a natural product isolated from the fungus Shiraia bambusicola.

Yi Chen, Z. Miao, Jian Ding, 2005, Biochemical and biophysical research communications.

Hereditary ataxia SCAN1 cells are defective for the repair of transcription-dependent topoisomerase I cleavage complexes.

K. Kohn, Y. Pommier, Z. Miao, 2006, DNA repair.

Increased PARP1‐DNA binding due to autoPARylation inhibition of PARP1 on DNA rather than PARP1‐DNA trapping is correlated with PARP1 inhibitor's cytotoxicity

Z. Miao, Yu-Nan Tian, Hua-Dong Chen, 2019, International journal of cancer.

Synthesis of isoquinolinone-based tricycles as novel poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors.

Z. Miao, Chunhao Yang, Jin-Xue He, 2014, Bioorganic & medicinal chemistry letters.

Design and synthesis of 2-(4,5,6,7-tetrahydrothienopyridin-2-yl)-benzoimidazole carboxamides as novel orally efficacious Poly(ADP-ribose)polymerase (PARP) inhibitors.

Xuxing Chen, Qian He, Qiufeng Liu, 2018, European journal of medicinal chemistry.

Novel PARP1/2 inhibitor mefuparib hydrochloride elicits potent in vitro and in vivo anticancer activity, characteristic of high tissue distribution

M. Wang, Yi Chen, Z. Miao, 2016, OncoTarget.

Development of Potent NEDD8-Activating Enzyme Inhibitors Bearing a Pyrimidotriazole Scaffold.

Z. Miao, Huaqian Ding, Ao Zhang, 2021, Journal of medicinal chemistry.

Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors.

Z. Miao, Hua-Dong Chen, Jin-Xue He, 2020, American journal of cancer research.

Discovery of potent 2,4-difluoro-linker poly(ADP-ribose) polymerase 1 inhibitors with enhanced water solubility and in vivo anticancer efficacy

Hualiang Jiang, Z. Miao, Jian Ding, 2017, Acta Pharmacologica Sinica.

Dual targeting of microtubule and topoisomerase II by α-carboline derivative YCH337 for tumor proliferation and growth inhibition

Yi Chen, Z. Miao, Jian Ding, 2015, Oncotarget.

MT119, a new planar‐structured compound, targets the colchicine site of tubulin arresting mitosis and inhibiting tumor cell proliferation

Yi Chen, Z. Miao, Jian Ding, 2011, International journal of cancer.

Cytotoxic polyhydroxylated steroids from the South China Sea soft coral Lobophytum sp.

Z. Miao, Bin Wu, Yue‐Wei Guo, 2019, Steroids.

Hypoxia induces universal but differential drug resistance and impairs anticancer mechanisms of 5-fluorouracil in hepatoma cells

Z. Miao, Xiangliang Yang, L. Gan, 2017, Acta Pharmacologica Sinica.

The p53 pathway is synergized by p38 MAPK signaling to mediate 11,11′‐dideoxyverticillin‐induced G2/M arrest

Yi Chen, Z. Miao, Jian Ding, 2005, FEBS letters.

Catalyst-free synthesis of benzofuran-fused pyrido[4,3-d]pyrimidines from 2-(2-hydroxyaryl)acetonitrile and 4,6-dichloropyrimidine-5-carbaldehyde through domino condensation reactions

Z. Miao, Chunhao Yang, Zhizhou Yue, 2014 .

MFTZ-1 reduces constitutive and inducible HIF-1α accumulation and VEGF secretion independent of its topoisomerase II inhibition

Z. Miao, Jian Ding, Lin-jiang Tong, 2009, Journal of cellular and molecular medicine.

Cytotoxic Nitrogenous Terpenoids from Two South China Sea Nudibranchs Phyllidiella pustulosa, Phyllidia coelestis, and Their Sponge-Prey Acanthella cavernosa

Z. Miao, Hong Wang, M. Gavagnin, 2019, Marine drugs.

Glycogen synthase kinase 3β inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer

Z. Miao, Yu-Nan Tian, Hua-Dong Chen, 2021, Cell Death & Disease.

Chemical Components of Dendrobium polyanthum

Z. Miao, You-Xing Zhao, Jun Zhou, 2009 .

Chemical constituents from the South China sea soft coral Sinularia humilis

Z. Miao, Yue‐Wei Guo, Meng-Jun Wu, 2020, Natural Product Research.

Synthesis and biological evaluation of 6H-pyrido[2',1':2,3]imidazo[4,5-c]isoquinolin-5(6H)-ones as antimitotic agents and inhibitors of tubulin polymerization.

Z. Miao, T. Meng, Yongliang Zhang, 2014, Bioorganic & medicinal chemistry.

New microtubulin inhibitor MT189 suppresses angiogenesis via the JNK-VEGF/VEGFR2 signaling axis.

Lin Xu, Z. Miao, Lin-jiang Tong, 2018, Cancer letters.

Characterization of mismatch and high-signal intensity probes associated with Affymetrix genechips

Yonghong Wang, Ernest S. Kawasaki, Yves Pommier, 2007, Bioinform..

Structure-based Discovery and Development of a Series of Potent and Selective Bromodomain and Extra-Terminal Protein Inhibitors.

Z. Miao, Jian Li, B. Xiong, 2019, Journal of medicinal chemistry.

Fragment-based drug discovery of 2-thiazolidinones as BRD4 inhibitors: 2. Structure-based optimization.

Yechun Xu, Lele Zhao, Z. Miao, 2015, Journal of medicinal chemistry.

Cytokeratin-RNA Cross-Linking Mediated by the Antitumor Aminoflavone, 5-Amino-2,3-fluorophenyl-6,8-difluoro-7-methyl-4H-1-benzopyran-4-one

Y. Pommier, T. Veenstra, Z. Miao, 2008, Journal of Pharmacology and Experimental Therapeutics.

Uncommon Bis‐quinolizidine Alkaloids from the Hainan Sponge Neopetrosia chaliniformi s

Z. Miao, Yucheng Gu, Chang-Yun Wang, 2021 .

YCH1899, a Highly Effective Phthalazin-1(2H)-one Derivative That Overcomes Resistance to Prior PARP Inhibitors.

Z. Miao, Chunhao Yang, Yong Gan, 2023, Journal of medicinal chemistry.

Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities.

Yi Chen, Z. Miao, Pingyuan Wang, 2023, European journal of medicinal chemistry.

The B-RafV600E inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury

Z. Miao, Jian Ding, B. Xiong, 2014, Cell Death and Disease.

Erectsterates A and B, a pair of novel highly degraded steroid derivatives from the South China Sea soft coral Sinularia erecta

Z. Miao, Yucheng Gu, Hui Luo, 2020, Steroids.

[Reversal of multidrug resistance by cyproheptadine in KBV200 cells].

Z. Miao, Y. Zhu, X. T. Li, 1997, Yao xue xue bao = Acta pharmaceutica Sinica.

Rapid access to α-carbolines via a one-pot tandem reaction of α,β-unsaturated ketones with 2-nitrophenylacetonitrile and the anti-proliferative activities of the products.

Z. Miao, Xiaofei Zhang, Chunhao Yang, 2014, Organic & biomolecular chemistry.

Three New Cytotoxic Monoterpenoid Bisindole Alkaloids from Tabernaemontana bufalina

Z. Miao, G. Qiu, You-sheng Cai, 2018, Planta Medica.

Drug Transporter-independent Liver Cancer Cell Killing by a Marine Steroid Methyl Spongoate via Apoptosis Induction*

Z. Miao, Jian Ding, Lin-jiang Tong, 2011, The Journal of Biological Chemistry.

Total synthesis of the marine cyclic depsipeptide viequeamide a.

Z. Miao, A. Zhang, Youjun Xu, 2013, Journal of natural products.

Design and synthesis of pyrido[3,2-α]carbazole derivatives and their analogues as potent antitumour agents.

Z. Miao, Zhizhou Yue, Chun-hao Yang, 2013, European journal of medicinal chemistry.

Discovery of a series of 1H-pyrrolo[2,3-b]pyridine compounds as potent TNIK inhibitors.

Tongchao Liu, Z. Miao, B. Xiong, 2020, Bioorganic & medicinal chemistry letters.

Characterization of the conversion between CD133+ and CD133- cells in colon cancer SW620 cell line

Yi Chen, Z. Miao, Jian Ding, 2012, Cancer biology & therapy.

Rh(III)-catalyzed redox-neutral C-H activation of pyrazolones: an economical approach for the synthesis of N-substituted indoles.

Z. Miao, Wei Li, Z. Fan, 2015, Organic letters.