S. Brookes

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The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2

Kevin Ryan, G. Peters, K. Vousden, 1998, The EMBO journal.

The Ets1 transcription factor is widely expressed during murine embryo development and is associated with mesodermal cells involved in morphogenetic processes such as organ formation.

M. Tymms, I. Kola, A. Green, 1993, Proceedings of the National Academy of Sciences of the United States of America.

D11S287, a putative oncogene on chromosome 11q13, is amplified and expressed in squamous cell and mammary carcinomas and linked to BCL-1.

E. Schuuring, G. Peters, S. Brookes, 1991, Oncogene.

Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts

G. Peters, B. McConnell, M. Starborg, 1998, Current Biology.

Contribution of p16(INK4a) to replicative senescence of human fibroblasts.

G. Peters, S. Brookes, J. Bond, 2004, Experimental cell research.

Functional, structural, and genetic evaluation of 20 CDKN2A germ line mutations identified in melanoma‐prone families or patients

G. Peters, G. Lenoir, S. Brookes, 2009, Human mutation.

CDK4 and CDK6 Delay Senescence by Kinase-Dependent and p16INK4a-Independent Mechanisms

G. Peters, M. Starborg, S. Brookes, 2007, Molecular and Cellular Biology.

A CDKN 2 A Mutation in Familial Melanoma that Abrogates Binding of p 16 INK 4 a to CDK 4 but not CDK 6

S. Manoukian, G. Peters, D. Delia, 2007 .

Evidence for a CDK4-dependent checkpoint in a conditional model of cellular senescence

G. Peters, E. Hara, S. Brookes, 2015, Cell cycle.

Tumorigenesis by mouse mammary tumor virus: Evidence for a common region for provirus integration in mammary tumors

G. Peters, S. Brookes, C. Dickson, 1983, Cell.

Sequence, topography and protein coding potential of mouse int‐2: a putative oncogene activated by mouse mammary tumour virus.

G. Peters, S. Brookes, C. Dickson, 1986, The EMBO journal.

The mouse homolog of the hst/k-FGF gene is adjacent to int-2 and is activated by proviral insertion in some virally induced mammary tumors.

G. Peters, S. Brookes, C. Dickson, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Amplified region of chromosome band 11q13 in breast and squamous cell carcinomas encompasses three CpG islands telomeric of FGF3, including the expressed gene EMS1

E. Schuuring, G. Peters, S. Brookes, 1993, Genes, chromosomes & cancer.

Linkage map of a region of human chromosome band 11q13 amplified in breast and squamous cell tumors

E. Schuuring, G. Peters, S. Brookes, 1992, Genes, chromosomes & cancer.

Biallelic Mutations in p16 INK4a Confer Resistance to Ras- and Ets-Induced Senescence in Human Diploid Fibroblasts

G. Peters, V. Bataille, E. Hara, 2002 .

Accumulation of p16INK4a in mouse fibroblasts as a function of replicative senescence and not of retinoblastoma gene status

G. Peters, S. Bates, E. Hara, 1997, Oncogene.

Contrasting behavior of the p18 INK4c and p16 INK4a tumor suppressors in both replicative and oncogene-induced senescence

G. Peters, S. Brookes, J. Rowe, 2011 .

Chromosome 11q13 abnormalities in human breast cancer.

G. Peters, S. Brookes, V. Fantl, 1993, Cancer surveys.

Proviral insertions near cyclin D1 in mouse lymphomas: a parallel for BCL1 translocations in human B-cell neoplasms.

G. Peters, S. Brookes, C. Dickson, 1992, Oncogene.

High-resolution in situ hybridization using DNA halo preparations.

J. Wiegant, L. Mullenders, S. Brookes, 1992, Human molecular genetics.

The mouse homologue of hst/k-FGF: sequence, genome organization and location relative to int-2.

G. Peters, S. Brookes, C. Dickson, 1989, Nucleic acids research.

The nuclear receptor NR2E1/TLX controls senescence

Simona Parrinello, G. Peters, S. Brookes, 2014, Oncogene.

A CDKN2A mutation in familial melanoma that abrogates binding of p16INK4a to CDK4 but not CDK6.

Janice Rowe, S. Manoukian, G. Peters, 2007, Cancer research.

The Significance of p16INK4a in Cell Defences Against Transformation

G. Peters, S. Brookes, J. Rowe, 2004, Cell cycle.

Biallelic Mutations in p16INK4a Confer Resistance to Ras- and Ets-Induced Senescence in Human Diploid Fibroblasts

G. Peters, V. Bataille, E. Hara, 2002, Molecular and Cellular Biology.

INK4a‐deficient human diploid fibroblasts are resistant to RAS‐induced senescence

G. Peters, K. Vousden, S. Bates, 2002, The EMBO journal.

Tumorigenesis by mouse mammary tumor virus: Proviral activation of a cellular gene in the common integration region int-2

G. Peters, S. Brookes, C. Dickson, 1984, Cell.

Two p16 (CDKN2A) germline mutations in 30 Israeli melanoma families

G. Peters, E. Friedman, S. Brookes, 2000, European Journal of Human Genetics.

Amplification of chromosome band 11q13 and a role for cyclin D1 in human breast cancer.

J. Bartek, G. Peters, S. Brookes, 1995, Cancer letters.

Role for the MOV10 RNA helicase in Polycomb-mediated repression of the INK4a tumor suppressor

G. Peters, E. Bernstein, S. Brookes, 2010, Nature Structural &Molecular Biology.

Germline mutations of the CDKN2 gene in UK melanoma families.

D. Bishop, J. Cuzick, E. Pinney, 1997, Human molecular genetics.

Chromosome 11q13 markers and D-type cyclins in breast cancer

G. Peters, S. Brookes, V. Fantl, 2004, Breast Cancer Research and Treatment.

Functional evaluation of tumour-specific variants of p16INK4a/CDKN2A: correlation with protein structure information

G. Peters, S. Brookes, N. McDonald, 1999, Oncogene.

Contrasting behavior of the p18INK4c and p16INK4a tumor suppressors in both replicative and oncogene-induced senescence.

G. Peters, S. Brookes, J. Rowe, 2012, Cancer research.

Senescence Suppressors in Both Replicative and Oncogene-Induced TumorINK 4 a and p 16 INK 4 cContrasting Behavior of the p 18 Updated

G. Peters, S. Brookes, J. Rowe, 2011 .

Contrasting Behavior of the p 18 INK 4 c and p 16 INK 4 a Tumor Suppressors in Both Replicative and Oncogene-Induced Senescence

G. Peters, S. Brookes, J. Rowe, 2011 .

CBX7 and miR‐9 are part of an autoregulatory loop controlling p16INK 4a

G. Peters, S. Brookes, J. Gil, 2015, Aging cell.

Genome-wide co-localization of Polycomb orthologs and their effects on gene expression in human fibroblasts

Harshil Patel, A. Stewart, G. Peters, 2014, Genome Biology.

Characterization, chromosome assignment, and segregation analysis of endogenous proviral units of mouse mammary tumor virus

G. Peters, C. Kozak, S. Brookes, 1986, Journal of virology.

Insertion elements and transitions in cloned mouse mammary tumour virus DNA: further delineation of the poison sequences.

G. Peters, S. Brookes, C. Dickson, 1986, Nucleic acids research.

Proviral insertions within the int-2 gene can generate multiple anomalous transcripts but leave the protein-coding domain intact

G. Peters, S. Brookes, C. Dickson, 1990, Journal of virology.

Conservation of protein coding potential in the long terminal repeats of exogenous and endogenous mouse mammary tumor viruses

G. Peters, S. Brookes, C. Dickson, 1982, Journal of virology.

Sequence organization of the human int-2 gene and its expression in teratocarcinoma cells.

G. Peters, S. Brookes, C. Dickson, 1989, Oncogene.

A putative int domain for mouse mammary tumor virus on mouse chromosome 7 is a 5' extension of int-2

G. Peters, S. Brookes, R. Michalides, 1989, Journal of virology.

Role of Polycomb Group Proteins in the DNA Damage Response – A Reassessment

G. Peters, S. Brookes, Nik Matthews, 2014, PloS one.

Activation of both Wnt-1 and Fgf-3 by insertion of mouse mammary tumor virus downstream in the reverse orientation: a reappraisal of the enhancer insertion model.

G. Peters, S. Brookes, C. Dickson, 1993, Virology.

Localization of four human chromosome 21 genes--SOD1, ETS2, IFNAR, and CBR--to two different chromosomes in the marsupial species Macropus eugenii.

J. Graves, M. Tymms, S. Brookes, 1992, Cytogenetics and cell genetics.

XPO7 is a tumor suppressor regulating p21CIP1-dependent senescence

J. Zuber, S. Brookes, Verena Wagner, 2021, Genes & development.

Breast and Squamous Cell Carcinomas Encompasses Three CpG Islands Telomeric of FGF3, Including the Expressed Gene

G. Peters, S. Brookes, R. Michalides, 2006 .