Z. Abdel‐Malek

M. B. Davis, G. Babcock, Z. Abdel‐Malek, 1998, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

alpha-Melanocortin and endothelin-1 activate antiapoptotic pathways and reduce DNA damage in human melanocytes.

G. Babcock, A. L. Kadekaro, Z. Abdel‐Malek, 2005, Cancer research.

The potential role of antioxidants in mitigating skin hyperpigmentation resulting from ultraviolet and visible light‐induced oxidative stress

T. Braunberger, Z. Abdel‐Malek, Henry W. Lim, 2018, Photodermatology, photoimmunology & photomedicine.

Chemoprevention agents for melanoma: A path forward into phase 3 clinical trials

Maria L. Wei, A. Marghoob, R. Dellavalle, 2018, Cancer.

Ultraviolet B light induces G1 arrest in human melanocytes by prolonged inhibition of retinoblastoma protein phosphorylation associated with long-term expression of the p21Waf-1/SDI-1/Cip-1 protein.

Z. Abdel‐Malek, E. Medrano, F. Yang, 1995, Cancer research.

Epidermal Melanocytes: Regulation of Their Survival, Proliferation, and Function in Human Skin

V. Swope, Z. Abdel‐Malek, 2011 .

Melanocortin receptors: their functions and regulation by physiological agonists and antagonists

Z. Abdel‐Malek, 2001, Cellular and Molecular Life Sciences CMLS.

The Melanocortin‐1 Receptor and Human Pigmentation

Z. Abdel‐Malek, I. Suzuki, C. Akcali, 1999, Annals of the New York Academy of Sciences.

Participation of the melanocortin-1 receptor in the UV control of pigmentation.

G. Barsh, M. B. Davis, Z. Abdel‐Malek, 1999, The journal of investigative dermatology. Symposium proceedings.

Differential Induction of Reactive Oxygen Species and Expression of Antioxidant Enzymes in Human Melanocytes Correlate with Melanin Content: Implications on the Response to Solar UV and Melanoma Susceptibility

K. Wakamatsu, S. Ito, V. Swope, 2022, Antioxidants.

Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation

K. Wakamatsu, S. Ito, D. Supp, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Significance of the Melanocortin 1 Receptor in Regulating Human Melanocyte Pigmentation, Proliferation, and Survival

A. L. Kadekaro, Z. Abdel‐Malek, R. Kavanagh, 2003, Annals of the New York Academy of Sciences.

Alpha-Melanocyte–Stimulating Hormone Suppresses Oxidative Stress through a p53-Mediated Signaling Pathway in Human Melanocytes

V. Swope, A. L. Kadekaro, Z. Abdel‐Malek, 2012, Molecular Cancer Research.

Endothelin stimulates chloride secretion across canine tracheal epithelium.

Z. Abdel‐Malek, G. Leikauf, C. A. Doupnik, 1991, The American journal of physiology.

The nature and biological effects of factors responsible for proliferation and differentiation of melanocytes.

V. Swope, Z. Abdel‐Malek, J. Nordlund, 1990, Pigment cell research.

Hormonal effects of vitamin D3 on epidermal melanocytes

V. Swope, Z. Abdel‐Malek, J. Nordlund, 1988, Journal of cellular physiology.

Endothelin‐1 and α‐melanocortin have redundant effects on global genome repair in UV‐irradiated human melanocytes despite distinct signaling pathways

V. Swope, Renny J. Starner, Z. Abdel‐Malek, 2020, Pigment cell & melanoma research.

Dark CPDs and photocarcinogenesis: the party continues after the lights go out

P. Cassidy, Z. Abdel‐Malek, 2015, Pigment cell & melanoma research.

Human Cutaneous Pigmentation

A. L. Kadekaro, Z. Abdel‐Malek, 2006 .

Human Pigmentation: Its Regulation by Ultraviolet Light and by Endocrine, Paracrine, and Autocrine Factors

A. L. Kadekaro, Z. Abdel‐Malek, 2007 .

Beyond red hair and sunburns: Uncovering the molecular mechanisms of MC1R signaling and repair of UV-induced DNA damage

P. Cassidy, S. Leachman, Z. Abdel‐Malek, 2015, The Journal of investigative dermatology.

Effects of commonly used mitogens on the cytotoxicity of 4-tertiary butylphenol to human melanocytes

Z. Abdel‐Malek, R. Boissy, Fan Yang, 1999, In Vitro Cellular & Developmental Biology - Animal.

Identification and sequencing of a putative variant of proopiomelanocortin in human epidermis and epidermal cells in culture.

S. Boyce, Z. Abdel‐Malek, J. Nordlund, 1998, The Journal of investigative dermatology.

The Expression of Proopiomelanocortin and Various POMC‐Derived Peptides in Mouse and Human Skin

Z. Abdel‐Malek, E. Medrano, J. Nordlund, 1993, Annals of the New York Academy of Sciences.

The enigma and challenges of vitiligo pathophysiology and treatment

A. Fleischer, Z. Abdel‐Malek, I. Hamzavi, 2020, Pigment cell & melanoma research.

Interleukins 1α and 6 and tumor necrosis factor-α are paracrine inhibitors of human melanocyte proliferation and melanogenesis

V. Swope, Z. Abdel‐Malek, J. Nordlund, 1991 .

Role of the Melanocyte in Epidermal Inflammatory and Immune Responses

Z. Abdel‐Malek, J. Nordlund, R. Boissy, 1988 .

PGE2 is a UVR‐inducible autocrine factor for human melanocytes that stimulates tyrosinase activation

Renny J. Starner, Z. Abdel‐Malek, G. Scott, 2010, Experimental dermatology.

Regulation of the human melanocortin 1 receptor expression in epidermal melanocytes by paracrine and endocrine factors and by ultraviolet radiation.

Z. Abdel‐Malek, I. Suzuki, M. C. Scott, 2002, Pigment cell research.

Development of hMC1R Selective Small Agonists for Sunless Tanning and Prevention of Genotoxicity of UV in Melanocytes.

V. Swope, Renny J. Starner, Z. Abdel‐Malek, 2021, The Journal of investigative dermatology.

Development of α-melanocortin analogs for melanoma prevention and targeting.

Z. Abdel‐Malek, 2010, Advances in experimental medicine and biology.

Walking in the footsteps of giants: melanocortins and human pigmentation, a historical perspective.

A. L. Kadekaro, Z. Abdel‐Malek, 2007, Pigment cell research.

In vitro modulation of proliferation and melanization of S91 melanoma cells by prostaglandins.

V. Swope, Z. Abdel‐Malek, J. Nordlund, 1987, Cancer research.

MC1R and the response of melanocytes to ultraviolet radiation.

A. L. Kadekaro, Z. Abdel‐Malek, V. Hearing, 2005, Mutation research.

Stepping up melanocytes to the challenge of UV exposure

V. Swope, A. L. Kadekaro, Z. Abdel‐Malek, 2010, Pigment cell & melanoma research.

Skin Cancer: Epidemiology, Clinical Manifestations, and Genetic and Molecular Aspects

A. L. Kadekaro, Z. Abdel‐Malek, Michelle A. Pipitone, 2005 .

Influence of α‐melanocyte‐stimulating hormone and of ultraviolet radiation on the transfer of melanosomes to keratinocytes

V. Ferrans, K. Wakamatsu, S. Ito, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The melanocortin 1 receptor is the principal mediator of the effects of agouti signaling protein on mammalian melanocytes.

G. Barsh, M. Ollmann, Z. Abdel‐Malek, 2001, Journal of cell science.

Interleukins 1 alpha and 6 and tumor necrosis factor-alpha are paracrine inhibitors of human melanocyte proliferation and melanogenesis.

V. Swope, Z. Abdel‐Malek, J. Nordlund, 1991, The Journal of investigative dermatology.

My Journey to the Land of Melanocortins How It Started and Where It Is Leading

Z. Abdel‐Malek, 2006 .

Activation of the cyclic AMP pathway by alpha-melanotropin mediates the response of human melanocytes to ultraviolet B radiation.

G. Babcock, Z. Abdel‐Malek, E. Medrano, 1998, Cancer research.

Binding of melanotropic hormones to the melanocortin receptor MC1R on human melanocytes stimulates proliferation and melanogenesis.

R. Cone, Z. Abdel‐Malek, J. Nordlund, 1996, Endocrinology.

Modulation of murine melanocyte function in vitro by agouti signal protein

G. Barsh, G. Imokawa, M. Ollmann, 1997, The EMBO journal.

Contribution of melanogenic proteins to the heterogeneous pigmentation of human melanocytes.

V. Swope, Z. Abdel‐Malek, J. Nordlund, 1993, Journal of cell science.

Proliferation and propagation of human melanocytes in vitro are affected by donor age and anatomical site.

V. Swope, Z. Abdel‐Malek, E. Medrano, 1994, Pigment cell research.

Stimulation of Cloudman melanoma tyrosinase activity occurs predominantly in G2 phase of the cell cycle.

V. Swope, Z. Abdel‐Malek, J. Nordlund, 1989, Experimental cell research.

Alteration of the Cloudman melanoma cell cycle by prostaglandins E1 and E2 determined by using a 5‐bromo‐2′‐deoxyuridine method of DNA analysis

V. Swope, Z. Abdel‐Malek, J. Nordlund, 1988, Journal of cellular physiology.

Regulation of the Mouse and Human Melanocortin-1 Receptor

Z. Abdel‐Malek, 2000 .

α-Melanocyte-Stimulating Hormone and Endothelin-1 Have Opposing Effects on Melanocyte Adhesion, Migration, and pp125FAKPhosphorylation

Z. Abdel‐Malek, G. Scott, L. Cassidy, 1997 .

The interaction of agouti signal protein and melanocyte stimulating hormone to regulate melanin formation in mammals.

G. Barsh, Z. Abdel‐Malek, V. Hearing, 1996, Pigment cell research.

MC1R, the cAMP pathway, and the response to solar UV: extending the horizon beyond pigmentation

Z. Abdel‐Malek, J. García-Borrón, C. Jiménez‐Cervantes, 2014, Pigment cell & melanoma research.

Signaling from the human melanocortin 1 receptor to ERK1 and ERK2 mitogen-activated protein kinases involves transactivation of cKIT.

Z. Abdel‐Malek, G. Ghanem, F. Journé, 2011, Molecular endocrinology.

Agouti signaling protein inhibits melanogenesis and the response of human melanocytes to alpha-melanotropin.

G. Barsh, M. Ollmann, Z. Abdel‐Malek, 1997, The Journal of investigative dermatology.

α‐MSH activates immediate defense responses to UV‐induced oxidative stress in human melanocytes

A. L. Kadekaro, Z. Abdel‐Malek, A. Xu, 2009, Pigment cell & melanoma research.

Defining MC1R Regulation in Human Melanocytes by Its Agonist α-Melanocortin and Antagonists Agouti Signaling Protein and β-Defensin 3

D. Supp, G. Babcock, V. Swope, 2012, The Journal of investigative dermatology.

Apoptotic pathways targeted by α-MSH in human melanocytes

A. L. Kadekaro, Z. Abdel‐Malek, 2008 .

β‐Defensin 3: a novel and unexpected key that unlocks the melanocortin 1 receptor

D. Supp, Z. Abdel‐Malek, 2007, Pigment cell & melanoma research.

Cutaneous photoprotection and melanoma susceptibility: reaching beyond melanin content to the frontiers of DNA repair.

K. Wakamatsu, S. Ito, A. L. Kadekaro, 2006, Frontiers in bioscience : a journal and virtual library.

Regulation of constitutive and UVR‐induced skin pigmentation by melanocortin 1 receptor isoforms

Z. Abdel‐Malek, V. Hearing, G. Costin, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Melanin content and MC1R function independently affect UVR-induced DNA damage in cultured human melanocytes.

K. Wakamatsu, S. Ito, G. Babcock, 2006, Pigment cell research.

Melanoma prevention strategy based on using tetrapeptide α‐MSH analogs that protect human melanocytes from UV‐induced DNA damage and cytotoxicity

G. Babcock, G. Millhauser, A. L. Kadekaro, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Diversity of pigmentation in cultured human melanocytes is due to differences in the type as well as quantity of melanin.

Shosuke Ito, Kazumasa Wakamatsu, K. Wakamatsu, 2006, Pigment cell research.

Human melanocortin 1 receptor variants, receptor function and melanocyte response to UV radiation.

Shosuke Ito, Kazumasa Wakamatsu, Joanna Groden, 2002, Journal of cell science.

Mitogen- and ultraviolet-B-induced signaling pathways in normal human melanocytes.

Z. Abdel‐Malek, Renny Kavanagh, Akihiro Tada, 2002, The Journal of investigative dermatology.

On the analysis of the pathophysiology of Chediak-Higashi syndrome. Defects expressed by cultured melanocytes.

Z. Abdel‐Malek, J. Nordlund, R. Boissy, 1994, Laboratory investigation; a journal of technical methods and pathology.

Pigment cell biology: an historical review.

Z. Abdel‐Malek, J. Nordlund, R. Boissy, 1989, The Journal of investigative dermatology.

Differentiation of mitotic melanoma cells from G2 cells and their isolation by use of 5-bromo-2'-deoxyuridine and propidium iodide.

V. Swope, Z. Abdel‐Malek, J. Nordlund, 1988, Cytometry.

Measurement of melanin metabolism in live cells by [U-13C]-tyrosine fate tracing using LC-MS.

K. Wakamatsu, S. Ito, Z. Abdel‐Malek, 2021, The Journal of investigative dermatology.

Synthesis of Interleukin-1a and by Normal Human Melanocytes

G. Babcock, V. Swope, Z. Abdel‐Malek, 1994 .

Melanocytes as Instigators and Victims of Oxidative Stress

S. Leachman, A. L. Kadekaro, Z. Abdel‐Malek, 2014, The Journal of investigative dermatology.

Synthesis of interleukin-1 alpha and beta by normal human melanocytes.

G. Babcock, V. Swope, Z. Abdel‐Malek, 1994, The Journal of investigative dermatology.

Melanocytes Stress through a p 53-Mediated Signaling Pathway in Human Stimulating Hormone Suppresses Oxidative − Alpha-Melanocyte

V. Swope, A. L. Kadekaro, Z. Abdel‐Malek, 2012 .

Mechanisms for post-inflammatory hyperpigmentation and hypopigmentation.

Z. Abdel‐Malek, J. Nordlund, 1988, Progress in clinical and biological research.

The melanocortin-1 receptor is a key regulator of human cutaneous pigmentation.

G. Barsh, S. Ito, Z. Abdel‐Malek, 2000, Pigment cell research.

Fueling Melanocytes with ATP from Keratinocytes Accelerates Melanin Synthesis.

Z. Abdel‐Malek, 2019, The Journal of investigative dermatology.

Light or Dark Pigmentation of Engineered Skin Substitutes Containing Melanocytes Protects against Ultraviolet Light-Induced DNA Damage In Vivo.

D. Supp, S. Boyce, Z. Abdel‐Malek, 2020, Journal of burn care & research : official publication of the American Burn Association.

D‐Isomeric replacements within the 6–9 core sequence of ac‐[Nle4]‐α‐MSH4–11‐NH2: A topological model for the solution conformation of α‐melanotropin

V. Hruby, Z. Abdel‐Malek, M. Hadley, 1986 .

Semi-rigid tripeptide agonists of melanocortin receptors.

Z. Abdel‐Malek, J. Knittel, C. Haskell-Luevano, 2009, Bioorganic & medicinal chemistry letters.

Endocrine factors as effectors of integumental pigmentation.

Z. Abdel‐Malek, Z A Abdel-Malek, 1988, Dermatologic clinics.

Comparison of the responses of human melanocytes with different melanin contents to ultraviolet B irradiation.

D. Barker, G. Babcock, Z. Abdel‐Malek, 1995, Cancer research.

Ultraviolet B light induces G1 arrest in human melanocytes by prolonged inhibition of retinoblastoma protein phosphorylation associated with long-term expression of the p21Waf-1/SDI-1/Cip-1 protein.

Z. Abdel‐Malek, E. Medrano, Fan Yang, 1995, Cancer research.

Being in the red: a no‐win situation with melanoma

S. Ito, Z. Abdel‐Malek, 2013 .

Suppression of MAPK signaling in BRAF‐activated PTEN‐deficient melanoma by blocking β‐catenin signaling in cancer‐associated fibroblasts

A. L. Kadekaro, Z. Abdel‐Malek, T. Andl, 2018, Pigment cell & melanoma research.

Pigmentation and inhibition of wound contraction by cultured skin substitutes with adult melanocytes after transplantation to athymic mice.

S. Boyce, Z. Abdel‐Malek, E. Medrano, 1993, The Journal of investigative dermatology.

Human Cutaneous Pigmentation A Collaborative Act in the Skin , Directed by Paracrine , Autocrine , and Endocrine Factors and the Environment

A. L. Kadekaro, Z. Abdel‐Malek, 2022 .

Distinct cAMP signaling microdomains differentially regulate melanosomal pH and pigmentation.

K. Wakamatsu, S. Ito, Z. Abdel‐Malek, 2023, The Journal of investigative dermatology.

N-terminal fatty acylated His-dPhe-Arg-Trp-NH(2) tetrapeptides: influence of fatty acid chain length on potency and selectivity at the mouse melanocortin receptors and human melanocytes.

Z. Abdel‐Malek, C. Haskell-Luevano, Carrie Haskell-Luevano, 2005, Journal of medicinal chemistry.

Alpha-melanocyte-stimulating hormone and endothelin-1 have opposing effects on melanocyte adhesion, migration, and pp125FAK phosphorylation.

Z. Abdel‐Malek, G. Scott, L. Cassidy, 1997, Experimental cell research.

A new role for epidermal cell-derived thymocyte activating factor/IL-1 as an antagonist for distinct epidermal cell function.

V. Swope, Z. Abdel‐Malek, J. Nordlund, 1989, Journal of immunology.