G. Jenkins

发表

Acute dosing and p53-deficiency promote cellular sensitivity to DNA methylating agents.

K. E. Chapman, S. Doak, G. Jenkins, 2015, Toxicological sciences : an official journal of the Society of Toxicology.

A novel, integrated in vitro carcinogenicity test to identify genotoxic and non-genotoxic carcinogens using human lymphoblastoid cells

Jatin R. Verma, G. Johnson, K. E. Chapman, 2017, Archives of Toxicology.

NanoGenotoxicology: the DNA damaging potential of engineered nanomaterials.

S. Doak, G. Jenkins, C. Wright, 2009, Biomaterials.

Vinblastine and diethylstilboestrol tested in the in vitro mammalian cell micronucleus test (MNvit) at Swansea University UK in support of OECD draft Test Guideline 487.

Adam D. Thomas, G. Johnson, S. Doak, 2010, Mutation research.

Influence of DNA Repair on Nonlinear Dose-Responses for Mutation

Adam D. Thomas, G. Johnson, S. Doak, 2013, Toxicological sciences : an official journal of the Society of Toxicology.

N-methylpurine DNA glycosylase plays a pivotal role in the threshold response of ethyl methanesulfonate-induced chromosome damage.

G. Johnson, S. Doak, G. Jenkins, 2011, Toxicological sciences : an official journal of the Society of Toxicology.

Nanomaterials and innate immunity: A perspective of the current status in nanosafety.

S. Doak, G. Jenkins, J. Cronin, 2020, Chemical research in toxicology.

Genotoxic capacity of Cd/Se semiconductor quantum dots with differing surface chemistries

S. Doak, G. Jenkins, J. Wills, 2015, Mutagenesis.

Multiple-endpoint in vitro carcinogenicity test in human cell line TK6 distinguishes carcinogens from non-carcinogens and highlights mechanisms of action

Jatin R. Verma, G. Johnson, K. E. Chapman, 2020, Archives of toxicology.

Comparison of passive-dosed and solvent spiked exposures of pro-carcinogen, benzo[a]pyrene, to human lymphoblastoid cell line, MCL-5.

K. E. Chapman, S. Doak, G. Jenkins, 2020, Toxicology in vitro : an international journal published in association with BIBRA.

Few-layer graphene induces both primary and secondary genotoxicity in epithelial barrier models in vitro

S. Doak, G. Jenkins, N. Hondow, 2021, Journal of Nanobiotechnology.

No-observed effect levels are associated with up-regulation of MGMT following MMS exposure.

G. Johnson, S. Doak, G. Jenkins, 2008, Mutation research.

Development of an in vitro PIG-A gene mutation assay in human cells

R. Walmsley, G. Johnson, G. Jenkins, 2017, Mutagenesis.

Cellular Defense Mechanisms Following Nanomaterial Exposure: A Focus on Oxidative Stress and Cytotoxicity

S. Doak, G. Jenkins, S. J. Evans, 2019, Biological Responses to Nanoscale Particles.

A comparison of the genotoxicity of benzo[a]pyrene in four cell lines with differing metabolic capacity.

G. Johnson, S. Doak, G. Jenkins, 2016, Mutation research. Genetic toxicology and environmental mutagenesis.

Is Nickel Chloride really a Non‐Genotoxic Carcinogen?

S. Doak, G. Jenkins, Leanne M Stannard, 2017, Basic & clinical pharmacology & toxicology.

An overview of bile-acid synthesis, chemistry and function

G. Jenkins, 2008 .

The jury is still out on the safety of silver nanoparticles

S. Doak, G. Jenkins, H. Haboubi, 2013, BMJ.

Investigation of J-shaped dose-responses induced by exposure to the alkylating agent N-methyl-N-nitrosourea.

K. E. Chapman, S. Doak, G. Jenkins, 2017, Mutation research.

Industrial-relevant TiO2 types do not promote cytotoxicity in the A549 or TK6 cell lines regardless of cell specific interaction.

S. Doak, G. Jenkins, N. Hondow, 2022, Toxicology in vitro : an international journal published in association with BIBRA.

In Vitro Three-Dimensional Liver Models for Nanomaterial DNA Damage Assessment.

M. J. Moné, B. van de Water, S. Doak, 2021, Small.

Plant-material deposition in the tropical Burdekin River, Australia: Implications for ancient fluvial sediments

G. Jenkins, J. Alexander, C. Fielding, 1999 .

Potential toxicity of superparamagnetic iron oxide nanoparticles (SPION)

Gareth J.S. Jenkins, Shareen H. Doak, Neenu Singh, 2010, Nano reviews.

Cell Type-Dependent Changes in CdSe/ZnS Quantum Dot Uptake and Toxic Endpoints

S. Doak, G. Jenkins, J. Wills, 2015, Toxicological sciences : an official journal of the Society of Toxicology.

Adaptation of the in vitro micronucleus assay for genotoxicity testing using 3D liver models supporting longer-term exposure durations

S. Doak, G. Jenkins, U. Shah, 2020, Mutagenesis.

Extraction and Amplification of 16S rRNA Genes from Deep Marine Sediments and Seawater to Assess Bacterial Community Diversity

G. Jenkins, J. Fry, C. Turley, 1995 .

Investigating mechanisms for non-linear genotoxic responses, and analysing their effects in binary combination

Jatin R. Verma, O. Bodger, Adam D. Thomas, 2012 .

Evaluation of the automated MicroFlow® and Metafer™ platforms for high-throughput micronucleus scoring and dose response analysis in human lymphoblastoid TK6 cells

Gareth J.S. Jenkins, Shareen H. Doak, George E. Johnson, 2016, Archives of Toxicology.

Abstracts of the 35th Annual Meeting of the United Kingdom Environmental Mutagen Society, 16th–18th July 2012 at Swansea University, UK Defining the chemistry associated with DNA binding to allow for prediction of mutagenicity by grouping and

Jatin R. Verma, P. White, G. Johnson, 2007 .

Comparison of the composition of bile acids in bile of patients with adenocarcinoma of the pancreas and benign disease

G. Jenkins, W. Griffiths, Yuqin Wang, 2017, The Journal of Steroid Biochemistry and Molecular Biology.

New approaches to advance the use of genetic toxicology analyses for human health risk assessment

Gareth J.S. Jenkins, Shareen H. Doak, Paul A. White, 2015 .

Diagnostic correlation between the expression of the DNA repair enzyme N-methylpurine DNA glycosylase and esophageal adenocarcinoma onset: a retrospective pilot study.

G. Johnson, G. Jenkins, A. Griffiths, 2013, Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus.

The clastogenicity of 4NQO is cell-type dependent and linked to cytotoxicity, length of exposure and p53 proficiency

G. Johnson, S. Doak, G. Jenkins, 2015, Mutagenesis.

Non-linear dose-response of DNA-reactive genotoxins: recommendations for data analysis.

D. Skibinski, G. Johnson, S. Doak, 2009, Mutation research.

The role of intracellular trafficking of CdSe/ZnS QDs on their consequent toxicity profile

U. Himmelreich, K. Braeckmans, S. Doak, 2017, Journal of Nanobiotechnology.

Deducing the cellular mechanisms associated with the potential genotoxic impact of gold and silver engineered nanoparticles upon different lung epithelial cell lines in vitro

K. E. Chapman, S. Doak, G. Jenkins, 2022, Nanotoxicology.

Quantum dot induced cellular perturbations involving varying toxicity pathways

T. S. Wilkinson, S. Doak, G. Jenkins, 2015 .

Assessing the transferability and reproducibility of 3D in vitro liver models from primary human multi-cellular microtissues to cell-line based HepG2 spheroids.

M. J. Moné, N. Jacobsen, B. van de Water, 2022, Toxicology in vitro : an international journal published in association with BIBRA.

Understanding the impact of more realistic low-dose, prolonged engineered nanomaterial exposure on genotoxicity using 3D models of the human liver

K. Jensen, S. Doak, G. Jenkins, 2021, Journal of Nanobiotechnology.

An Alternative Perspective towards Reducing the Risk of Engineered Nanomaterials to Human Health.

Shareen H Doak, Martin J D Clift, Gareth J S Jenkins, 2020, Small.

Detection of urethane-induced genotoxicity in vitro using metabolically competent human 2D and 3D spheroid culture models.

Jatin R. Verma, G. Johnson, K. E. Chapman, 2020, Mutagenesis.

The role of iron redox state in the genotoxicity of ultrafine superparamagnetic iron oxide nanoparticles.

S. Doak, G. Jenkins, C. Wright, 2012, Biomaterials.

Recommendations, evaluation and validation of a semi-automated, fluorescent-based scoring protocol for micronucleus testing in human cells.

Shareen H Doak, George E Johnson, Andrew D Scott, 2014, Mutagenesis.

Genetic toxicity assessment of engineered nanoparticles using a 3D in vitro skin model (EpiDerm™)

Richard A. Brown, P. White, Adam D. Thomas, 2016, Particle and Fibre Toxicology.

Single-walled carbon nanotubes: differential genotoxic potential associated with physico-chemical properties

A. Barron, S. Doak, G. Jenkins, 2013, Nanotoxicology.

Dextran Coated Ultrafine Superparamagnetic Iron Oxide Nanoparticles: Compatibility with Common Fluorometric and Colorimetric Dyes

Shareen H. Doak, Chris J. Wright, Neenu Singh, 2011, Analytical chemistry.

Interlaboratory comparison of an intestinal triple culture to confirm transferability and reproducibility

Angela A M Kämpfer, G. Jenkins, B. Rothen‐Rutishauser, 2022, In vitro models.

Investigating FlowSight® imaging flow cytometry as a platform to assess chemically induced micronuclei using human lymphoblastoid cells in vitro

Jatin R. Verma, P. Rees, H. Summers, 2018, Mutagenesis.

Pro-oxidant induced DNA damage in human lymphoblastoid cells: homeostatic mechanisms of genotoxic tolerance.

G. Johnson, S. Doak, G. Jenkins, 2012, Toxicological sciences : an official journal of the Society of Toxicology.

Do dose response thresholds exist for genotoxic alkylating agents?

G. Jenkins, G. Johnson, S. Doak, 2005, Mutagenesis.

Confounding experimental considerations in nanogenotoxicology.

P. M. Williams, P. Williams, G. Jenkins, 2009, Mutagenesis.

Investigating STEAP2 as a potential therapeutic target for the treatment of aggressive prostate cancer.

S. Doak, G. Jenkins, R. Conlan, 2023, Cellular and Molecular Biology.

In vitro genotoxicity testing strategy for nanomaterials and the adaptation of current OECD guidelines

G. Jenkins, S. Doak, G. Jenkins, 2012, Mutation research.

Genetic pathways involved in the progression of Barrett's metaplasia to adenocarcinoma

G. Jenkins, J. Baxter, J. Parry, 2002, The British journal of surgery.

Chromosome 4 hyperploidy represents an early genetic aberration in premalignant Barrett’s oesophagus

G. Jenkins, J. Baxter, E. Parry, 2003, Gut.

The bile acid deoxycholic acid (DCA) at neutral pH activates NF-kappaB and induces IL-8 expression in oesophageal cells in vitro.

G. Jenkins, J. Baxter, J. Parry, 2003, Carcinogenesis.

Automation and validation of micronucleus detection in the 3D EpiDerm™ human reconstructed skin assay and correlation with 2D dose responses

S. Doak, G. Jenkins, S. Pfuhler, 2014, Mutagenesis.

Investigation of J-shaped dose-responses induced by exposure to the alkylating agent N-methyl-N-nitrosourea.

S. Doak, G. Jenkins, G. Hoffmann, 2017, Mutation research.

An integrated in vitro carcinogenicity test that distinguishes between genotoxic carcinogens, non-genotoxic carcinogens, and non-carcinogens

S. Doak, G. Jenkins, U. Shah, 2024, Mutagenesis.

Multi-endpoint analysis of cadmium chloride-induced genotoxicity shows role for reactive oxygen species and p53 activation in DNA damage induction, cell cycle irregularities, and cell size aberrations

S. Doak, G. Jenkins, A. Doherty, 2023, Mutagenesis.

Jatin R. Verma, S. Doak, G. Jenkins, 2012 .