S. Levison

发表

Molecular features of neural stem cells enable their enrichment using pharmacological inhibitors of survival‐promoting kinases

C. Y. Brazel, Abdulaziz A. Alaythan, R. Felling, 2014, Journal of neurochemistry.

IGF‐II Promotes Stemness of Neural Restricted Precursors

S. Levison, T. Wood, A. Ziegler, 2012, Stem cells.

ActivationoftheMammalianTargetofRapamycin(mTOR) IsEssentialforOligodendrocyteDifferentiation

S. Levison, H. J. Kim, 2009 .

Mini review

S. Levison, V. Yong, C. Raggi, 2004 .

Subacute Transplantation of Native and Genetically Engineered Neural Progenitors Seeded on Microsphere Scaffolds Promote Repair and Functional Recovery After Traumatic Brain Injury

F. Calderon, S. Levison, C. Gandhi, 2019, ASN neuro.

IL‐6‐type cytokines enhance epidermal growth factor‐stimulated astrocyte proliferation

S. Levison, F. Jiang, Olivia K. Stoltzfus, 2000, Glia.

Oligodendrocyte progenitor proliferation is disinhibited following traumatic brain injury in LIF heterozygous mice

S. Levison, Michelle J. Frondelli, Marie L. Mather, 2020, bioRxiv.

Interleukin-1 and the Interleukin-1 Type 1 Receptor are Essential for the Progressive Neurodegeneration that Ensues Subsequent to a Mild Hypoxic/Ischemic Injury

S. Levison, A. Basu, D. Mauger, 2005, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Developmental IL-6 Exposure Favors Production of PDGF-Responsive Multipotential Progenitors at the Expense of Neural Stem Cells and Other Progenitors

S. Levison, F. Velloso, V. H. Savanur, 2020, Stem cell reports.

Divergent glial fibrillary acidic protein and its mRNA in the activated supraoptic nucleus

S. Levison, A. Salm, P. Albrecht, 2005, Neuroscience Letters.

Delayed ALK5 inhibition improves functional recovery in neonatal brain injury

S. Levison, M. Guardia Clausi, 2017, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

The FLT3 Tyrosine Kinase Receptor Inhibits Neural Stem/Progenitor Cell Proliferation and Collaborates with NGF to Promote Neuronal Survival

C. Y. Brazel, S. Levison, B. Pytowski, 2001, Molecular and Cellular Neuroscience.

Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Signaling and Cell Death in the Immature Central Nervous System after Hypoxia-Ischemia and Inflammation

P. Gressens, C. Thornton, H. Hagberg, 2014, The Journal of Biological Chemistry.

Astrocytes and developmental white matter disorders.

S. Levison, E. Sen, 2006, Mental retardation and developmental disabilities research reviews.

Subventricular zone adult mouse neural stem cells require insulin receptor for self-renewal

A. Fiser, S. Levison, N. Tapinos, 2022, Stem cell reports.

Egr-1 is a critical regulator of EGF-receptor-mediated expansion of subventricular zone neural stem cells and progenitors during recovery from hypoxia–hypoglycemia

Yuhui Jiang, S. Kotenko, S. Levison, 2013, ASN neuro.

Hyperoxia Inhibits the Growth of Mouse Forebrain Oligodendrocyte Progenitors

P. Canoll, S. Levison, T. Wood, 2021, bioRxiv.

CNTF-Activated Astrocytes Release a Soluble Trophic Activity for Oligodendrocyte Progenitors

S. Levison, P. Albrecht, Jonathan C. Enterline, 2007, Neurochemical Research.

Ciliary neurotrophic factor induces expression of the IGF type I receptor and FGF receptor 1 mRNAs in adult rat brain oligodendrocytes

S. Levison, T. Wood, F. Jiang, 1999, Journal of neuroscience research.

Multimarker Flow Cytometric Characterization, Isolation and Differentiation of Neural Stem Cells and Progenitors of the Normal and Injured Mouse Subventricular Zone

S. Levison, A. Ziegler, M. Goodus, 2015 .

Anti-ganglioside antibodies reveal subsets of cultured rat dorsal root ganglion neurons

K. McCarthy, S. Levison, F. A. Ashton, 1990, Brain Research.

Gray Matter Oligodendrocyte Progenitors and Neurons Die Caspase-3 Mediated Deaths Subsequent to Mild Perinatal Hypoxic/Ischemic Insults

S. Levison, Raymond P. Rothstein, 2005, Developmental Neuroscience.

Ciliary neurotrophic factor (CNTF) plus soluble CNTF receptor α increases cyclooxygenase-2 expression, PGE2 release and interferon-γ-induced CD40 in murine microglia

S. Levison, Hsiao-Wen Lin, M. Jain, 2009, Journal of Neuroinflammation.

Pro‐regenerative properties of cytokine‐activated astrocytes

S. Levison, V. Yong, Christina M. Liberto, 2004, Journal of neurochemistry.

Tethered growth factors on biocompatible scaffolds improve stemness of cultured rat and human neural stem cells and growth of oligodendrocyte progenitors.

S. Levison, N. Skop, Deborah E Rothbard, 2017, Methods.

Ciliary Neurotrophic Factor Activates Spinal Cord Astrocytes, Stimulating Their Production and Release of Fibroblast Growth Factor-2, to Increase Motor Neuron Survival

R. Levenson, S. Levison, P. Albrecht, 2002, Experimental Neurology.

Astrocytes produce CNTF during the remyelination phase of viral-induced spinal cord demyelination to stimulate FGF-2 production

Jonathan R. Enterline, R. Armstrong, S. Levison, 2003, Neurobiology of Disease.

Front & Back Matter

S. Levison, 2017, Developmental Neuroscience.

Front & Back Matter

G. Coukos, J. Cunha-Vaz, G. Soubrane, 2017, Developmental Neuroscience.

Interleukin-6 (IL-6), a 26 kDa, alpha-helical protein, is produced locally in the nervous system by astrocytes, microglia, and neurons, and is important in activating infiltrating macrophages, regulating B cell growth and differentiation as well as inducing T cell responses (Frei

S. Levison, Hsiao-Wen Lin, 2009 .

Ciliary Neurotrophic Factor Stimulates Astroglial Hypertrophyin Vivoandin Vitro

S. Levison, S. Hudgins, 1998, Experimental Neurology.

Cytokines regulate IGF binding proteins in the cns.

S. Levison, T. Wood, S. L. O'Donnell, 1995, Progress in growth factor research.

Comparison and quantitation of Ia antigen expression on cultured macroglia and ameboid microglia from Lewis rat cerebral cortex: analyses and implications

S. Levison, J. Ting, A. Sasaki, 1989, Journal of Neuroimmunology.

The migrational patterns and developmental fates of glial precursors in the rat subventricular zone are temporally regulated.

S. Levison, J. Goldman, S W Levison, 1993, Development.

Leukemia Inhibitory Factor Is Essential for Subventricular Zone Neural Stem Cell and Progenitor Homeostasis as Revealed by a Novel Flow Cytometric Analysis

S. Levison, Qiong Gan, K. Buono, 2012, Developmental Neuroscience.

Responses of the SVZ to Hypoxia and Hypoxia/Ischemia

R. Felling, S. Levison, H. VanGuider, 2006 .

Neural Stem Cells in the Subventricular Zone Are a Source of Astrocytes and Oligodendrocytes, but Not Microglia

S. Levison, A. Basu, Stuart K Druckman, 2003, Developmental Neuroscience.

An improved method for propagating oligodendrocyte progenitors in vitro

S. Levison, G. M. Young, 1997, Journal of Neuroscience Methods.

Astroglia in culture

K. McCarthy, S. Levison, 1991 .

Differential suppression of interferon-γ-induced Ia antigen expression on cultured rat astroglia and microglia by second messengers☆

S. Levison, J. Ting, A. Sasaki, 1990, Journal of Neuroimmunology.

Vascular Endothelial Growth Factors A and C are Induced in the SVZ Following Neonatal Hypoxia–Ischemia and Exert Different Effects on Neonatal Glial Progenitors

S. Levison, J. Bain, Lisamarie Moore, 2013, Translational Stroke Research.

Differential expression of protein tyrosine kinase genes during microglial activation

S. Levison, A. Basu, R. Milner, 2002, Glia.

Expression of the anaphylatoxin C5a receptor in the oligodendrocyte lineage

S. Barnum, S. Levison, S. Nataf, 2001, Brain Research.

Ciliary neurotrophic factor stimulates nuclear hypertrophy and increases the GFAP content of cultured astrocytes

S. Levison, J. Crawford, S. Hudgins, 1998, Brain Research.

Schwann cells influence the expression of ganglioside GD3 by rat dorsal root ganglion neurons

K. McCarthy, S. Levison, 1989, Journal of Neuroimmunology.

Glutamate enhances survival and proliferation of neural progenitors derived from the subventricular zone

C. Y. Brazel, S. Levison, J. Nuñez, 2005, Neuroscience.

Acute Exposure to CNTFin VivoInduces Multiple Components of Reactive Gliosis

S. Levison, T. Wood, M. Ducceschi, 1996, Experimental Neurology.

Ciliary neurotrophic factor stimulates astroglial hypertrophy in vivo and in vitro.

S. Levison, S. Hudgins, 1998, Experimental neurology.

Mechanisms of Mouse Neural Precursor Expansion after Neonatal Hypoxia-Ischemia

Yuhui Jiang, S. Levison, M. Guardia Clausi, 2015, The Journal of Neuroscience.

Death effector activation in the subventricular zone subsequent to perinatal hypoxia/ischemia

Changlian Zhu, K. Blomgren, B. Bahr, 2007, Journal of neurochemistry.

Damage to the Choroid Plexus, Ependyma and Subependyma as a Consequence of Perinatal Hypoxia/Ischemia

S. Levison, Raymond P. Rothstein, 2003, Developmental Neuroscience.

Neuroinflammation and Both Cytotoxic and Vasogenic Edema Are Reduced in Interleukin-1 Type 1 Receptor-Deficient Mice Conferring Neuroprotection

S. Levison, A. Basu, Hsiao-Wen Lin, 2005, Stroke.

Analyzing mouse neural stem cell and progenitor cell proliferation using EdU incorporation and multicolor flow cytometry

S. Levison, F. Velloso, Michelle J. Frondelli, 2021, STAR protocols.

CHAPTER 1 – Astrocyte Origins

S. Levison, J. Goldman, 1993 .

Unmasking the responses of the stem cells and progenitors in the subventricular zone after neonatal and pediatric brain injuries

S. Levison, E. Kumari, M. Clausi, 2016, Neural regeneration research.

Defining the Critical Period for Neocortical Neurogenesis after Pediatric Brain Injury

Zhengang Yang, Yuhui Jiang, S. Levison, 2010, Developmental Neuroscience.

TGFβ1: Friend or Foe During Recovery in Encephalopathy

S. Levison, Brian H. Kim, 2018, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

Characterization and Partial Purification of AIM: A Plasma Protein That Induces Rat Cerebral Type 2 Astroglia from Bipotential Glial Progenitors

K. McCarthy, S. Levison, 1991, Journal of neurochemistry.

Expression of mouse ovarian insulin growth factor system components during follicular development and atresia.

S. Levison, T. Wood, J. Hammond, 1998, Endocrinology.

Neural Stem Cells in Adult Mammals are not Astrocytes

P. Rakić, V. Parpura, S. Levison, 2022, ASN neuro.

TGFß1 Stimulates the Over-Production of White Matter Astrocytes from Precursors of the “Brain Marrow” in a Rodent Model of Neonatal Encephalopathy

Zhengang Yang, S. Levison, A. Ziegler, 2010, PloS one.

Neuroprotective effect of lipopolysaccharides in a dual-hit rat pup model of preterm hypoxia–ischemia

S. Levison, A. Evangelou, Dau-Jy Lu, 2022, Neuroscience Letters.

Proneurotrophins Induce Apoptotic Neuronal Death After Controlled Cortical Impact Injury in Adult Mice

S. Levison, Veera D’mello, W. Friedman, 2020, ASN neuro.

Neural Stem/Progenitor Cells Participate in the Regenerative Response to Perinatal Hypoxia/Ischemia

Zhengang Yang, E. Bongarzone, R. Felling, 2006, The Journal of Neuroscience.

Interleukin‐1: A master regulator of neuroinflammation

S. Levison, A. Basu, J. K. Krady, 2004, Journal of neuroscience research.

Diabetic retinopathy: more than meets the eye.

T. Gardner, S. Levison, A. Barber, 2002, Survey of ophthalmology.

The Ins2Akita mouse as a model of early retinal complications in diabetes.

T. Gardner, S. Levison, Chad E. N. Reiter, 2005, Investigative ophthalmology & visual science.

Heparin crosslinked chitosan microspheres for the delivery of neural stem cells and growth factors for central nervous system repair.

F. Calderon, S. Levison, C. Gandhi, 2013, Acta biomaterialia.

The role of inflammation in perinatal brain injury

D. Ferriero, P. Gressens, S. Vannucci, 2015, Nature Reviews Neurology.

17β-Estradiol protects the neonatal brain from hypoxia–ischemia

Zhengang Yang, Yuhui Jiang, S. Levison, 2007, Experimental Neurology.

Stem cell therapies for perinatal brain injuries.

S. Levison, H. Mehmet, R. Vawda, 2007, Seminars in fetal & neonatal medicine.

Insulin-like Growth Factor II: An Essential Adult Stem Cell Niche Constituent in Brain and Intestine

I. Sandovici, S. Levison, T. Wood, 2019, Stem cell reports.

Insulin and IGF receptor signalling in neural-stem-cell homeostasis

S. Levison, T. Wood, A. Ziegler, 2015, Nature Reviews Endocrinology.

Both oligodendrocytes and astrocytes develop from progenitors in the subventricular zone of postnatal rat forebrain

S. Levison, J. Goldman, 1993, Neuron.

Transforming growth factor beta1 prevents IL-1beta-induced microglial activation, whereas TNFalpha- and IL-6-stimulated activation are not antagonized.

Jonathan R. Enterline, S. Levison, A. Basu, 2002, Glia.

Multipotential and lineage restricted precursors coexist in the mammalian perinatal subventricular zone

S. Levison, J. Goldman, 1997, Journal of neuroscience research.

Activation of the Mammalian Target of Rapamycin (mTOR) Is Essential for Oligodendrocyte Differentiation

S. Levison, T. Wood, W. A. Tyler, 2009, The Journal of Neuroscience.

A role for ciliary neurotrophic factor as an inducer of reactive gliosis, the glial response to central nervous system injury.

C. Winter, D. Hirsh, S. Levison, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Ciliary neurotrophic factor and interleukin‐6 differentially activate microglia

S. Levison, A. Basu, Hsiao-Wen Lin, 2008, Journal of neuroscience research.

Roles of the mammalian subventricular zone in brain development

C. Y. Brazel, S. Levison, Michael J Romanko, 2003, Progress in Neurobiology.

Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy.

T. Gardner, S. Levison, A. Basu, 2005, Diabetes.

Leukemia Inhibitory Factor Is Required for Subventricular Zone Astrocyte Progenitor Proliferation and for Prokineticin-2 Production after a Closed Head Injury in Mice

S. Levison, Michelle J. Frondelli, 2021, Neurotrauma reports.

Astrocyte‐produced leukemia inhibitory factor expands the neural stem/progenitor pool following perinatal hypoxia–ischemia

R. Felling, S. Levison, M. Batish, 2016, Journal of neuroscience research.

Pathophysiology of Perinatal Hypoxia-Ischemia and the Prospects for Repair from Endogenous and Exogenous Stem Cells

S. Levison, M. Covey, 2006 .

Roles of the mammalian subventricular zone in cell replacement after brain injury

Ryan J. Felling, J. Fike, C. Y. Brazel, 2004, Progress in Neurobiology.

Brain injury expands the numbers of neural stem cells and progenitors in the SVZ by enhancing their responsiveness to EGF

S. Kotenko, R. Felling, S. Levison, 2009, ASN neuro.

Hypoxia/ischemia expands the regenerative capacity of progenitors in the perinatal subventricular zone

S. Levison, Z. Yang, Z. Yang, 2006, Neuroscience.

Hypoxia/Ischemia Depletes the Rat Perinatal Subventricular Zone of Oligodendrocyte Progenitors and Neural Stem Cells

Susan J. Vannucci, S. Vannucci, S. Levison, 2001, Developmental Neuroscience.

Neuroregenerative and protective functions of Leukemia Inhibitory Factor in perinatal hypoxic-ischemic brain injury

S. Levison, Jie Lin, Y. Niimi, 2020, Experimental Neurology.

Pediatric brain repair from endogenous neural stem cells of the subventricular zone

S. Levison, Y. Niimi, Yusuke Niimi, 2018, Pediatric Research.

C6‐ceramide‐coated catheters promote re‐endothelialization of stretch‐injured arteries

S. Levison, M. Kester, N. Weber, 2008, Vascular disease prevention.

Pre-conditioning induces the precocious differentiation of neonatal astrocytes to enhance their neuroprotective properties

S. Vannucci, S. Levison, A. Basu, 2011, ASN neuro.

Modestly increasing systemic interleukin-6 perinatally disturbs secondary germinal zone neurogenesis and gliogenesis and produces sociability deficits

S. Levison, F. Velloso, I. Carcea, 2021, Brain, Behavior, and Immunity.

Perinatal Inflammation Disturbs Secondary Germinal Zone Neurogenesis and Gliogenesis Producing Deficits in Sociability

S. Levison, F. Velloso, I. Carcea, 2021, bioRxiv.

The gp 120 glycoprotein of human immunodeficiency virus type 1 binds to sensory ganglion neurons

G. Rosoklija, S. Levison, S. Lederman, 1993, Annals of neurology.

Expression of Mouse Ovarian Insulin Growth Factor System Components During Follicular Development and Atresia* * This work was supported by NIH Grant HD-24565 (to J.M.H.) and an NIH fellowship (to S.A.W).

S. Levison, T. Wood, J. Hammond, 1998, Endocrinology.

Insulin-Like Growth Factor Receptor Signaling is Necessary for Epidermal Growth Factor Mediated Proliferation of SVZ Neural Precursors in vitro Following Neonatal Hypoxia–Ischemia

S. Levison, T. Wood, A. Ziegler, 2014, Frontiers in Neurology.

Improvements in biomaterial matrices for neural precursor cell transplantation

F. Calderon, S. Levison, C. Gandhi, 2014, Molecular and Cellular Therapies.

Astrogliosis is delayed in type 1 interleukin-1 receptor-null mice following a penetrating brain injury

S. Levison, A. Basu, Hsiao-Wen Lin, 2006, Journal of Neuroinflammation.

Ceramide-Coated Balloon Catheters Limit Neointimal Hyperplasia After Stretch Injury in Carotid Arteries

S. Levison, L. Sandirasegarane, M. Kester, 2000, Circulation research.

Mechanisms of Tertiary Neurodegeneration after Neonatal Hypoxic-Ischemic Brain Damage.

P. Gressens, S. Levison, B. Fleiss, 2021, Pediatric medicine.

Moderately Inducing Autophagy Reduces Tertiary Brain Injury after Perinatal Hypoxia-Ischemia

S. Levison, Radek Dobrowolski, Maciej Jeziorek, 2020, bioRxiv.

Optimizing a multifunctional microsphere scaffold to improve neural precursor cell transplantation for traumatic brain injury repair

F. Calderon, S. Levison, C. Gandhi, 2016, Journal of tissue engineering and regenerative medicine.

Ionizing Radiation Perturbs Cell Cycle Progression of Neural Precursors in the Subventricular Zone Without Affecting Their Long-Term Self-Renewal

S. Levison, E. Azzam, S. M. de Toledo, 2015, ASN neuro.

Delayed IGF-1 Administration Rescues Oligodendrocyte Progenitors from Glutamate-Induced Cell Death and Hypoxic-Ischemic Brain Damage

H. Hagberg, S. Levison, T. Wood, 2007, Developmental Neuroscience.

Sustained neocortical neurogenesis after neonatal hypoxic/ischemic injury

Li Ni, Zhengang Yang, S. Levison, 2007, Annals of neurology.

Olig1 is required for noggin‐induced neonatal myelin repair

D. Rowitch, John C. Silbereis, S. Levison, 2017, Annals of neurology.

Identification of Bax-interacting proteins in oligodendrocyte progenitors during glutamate excitotoxicity and perinatal hypoxia–ischemia

S. Levison, T. Wood, M. Jain, 2013, ASN neuro.

Enhanced neurogenesis following stroke

R. Felling, S. Levison, Ryan J. Felling, 2003, Journal of neuroscience research.

Transforming growth factor β1 prevents IL‐1β–induced microglial activation, whereas TNFα‐ and IL‐6–stimulated activation are not antagonized

Jonathan R. Enterline, S. Levison, A. Basu, 2002 .

Astrocytic ceruloplasmin expression, which is induced by IL‐1β and by traumatic brain injury, increases in the absence of the IL‐1 type 1 receptor

S. Levison, A. Basu, J. K. Krady, 2003, Glia.

Cycling cells in the adult rat neocortex preferentially generate oligodendroglia

S. Levison, J. Goldman, G. M. Young, 1999, Journal of neuroscience research.

Neural Stem Cells in the Subventricular Zone are Resilient to Hypoxia/Ischemia whereas Progenitors are Vulnerable

S. Levison, Michael J Romanko, Raymond P Rothstein, 2004, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Perinatal Hypoxia/Ischemia Damages and Depletes Progenitors from the Mouse Subventricular Zone

C. Y. Brazel, S. Levison, Steven W. Levison, 2004, Developmental Neuroscience.

Perinatal Hypoxia-Ischemia Induces Apoptotic and Excitotoxic Death of Periventricular White Matter Oligodendrocyte Progenitors

S. Levison, T. Wood, J. Ness, 2001, Developmental Neuroscience.

Oligodendrocyte progenitor proliferation is disinhibited following traumatic brain injury in leukemia inhibitory factor heterozygous mice

S. Levison, Michelle J. Frondelli, Marie L. Mather, 2021, Journal of neuroscience research.

PDGF-responsive progenitors persist in the subventricular zone across the lifespan

S. Levison, J. Loh, J. Bain, 2013, ASN neuro.

Cellular Heterogeneity of the Neonatal SVZ and its Contributions to Forebrain Neurogenesis and Gliogenesis

S. Levison, J. Goldman, 2006 .

The Type 1 Interleukin-1 Receptor Is Essential for the Efficient Activation of Microglia and the Induction of Multiple Proinflammatory Mediators in Response to Brain Injury

S. DeKosky, S. Levison, A. Basu, 2002, The Journal of Neuroscience.