J. Sugatani

发表

Magnesium deficiency suppresses cell cycle progression mediated by increase in transcriptional activity of p21Cip1 and p27Kip1 in renal epithelial NRK‐52E cells

A. Ikari, H. Sawada, Ayumi Sanada, 2011, Journal of cellular biochemistry.

TRPM6 expression and cell proliferation are up-regulated by phosphorylation of ERK1/2 in renal epithelial cells.

A. Ikari, H. Sawada, Y. Yamazaki, 2008, Biochemical and biophysical research communications.

INDUCTION OF DETOXIFYING ENZYMES IN RODENT WHITE ADIPOSE TISSUE BY ARYL HYDROCARBON RECEPTOR AGONISTS AND ANTIOXIDANTS

J. Sugatani, K. Yoshinari, M. Miwa, 2006, Drug Metabolism and Disposition.

Characterization of serum platelet-activating factor (PAF) acetylhydrolase. Correlation between deficiency of serum PAF acetylhydrolase and respiratory symptoms in asthmatic children.

J. Sugatani, M. Matsumoto, M. Miwa, 1988, The Journal of clinical investigation.

Hepatic CYP3A Expression is Attenuated in Obese Mice Fed a High-Fat Diet

J. Sugatani, K. Yoshinari, M. Miwa, 2006, Pharmaceutical Research.

Nutritional Status Affects Fluvastatin-Induced Hepatotoxicity and Myopathy in Rats

A. Ikari, J. Sugatani, S. Ikushiro, 2010, Drug Metabolism and Disposition.

Threonine-408 Regulates the Stability of Human Pregnane X Receptor through Its Phosphorylation and the CHIP/Chaperone-Autophagy Pathway

A. Ikari, Y. Yamazaki, J. Sugatani, 2016, Drug Metabolism and Disposition.

DMD066308 137..150

A. Ikari, Y. Yamazaki, J. Sugatani, 2015 .

Involvement of a cyclic adenosine monophosphate–dependent signal in the diet‐induced canalicular trafficking of adenosine triphosphate–binding cassette transporter g5/g8

A. Ikari, Y. Yamazaki, J. Sugatani, 2015, Hepatology.

Diet-induced lipid accumulation in liver enhances ATP-binding cassette transporter g5/g8 expression in bile canaliculi.

A. Ikari, Y. Yamazaki, J. Sugatani, 2011, Drug metabolism and pharmacokinetics.

Hyperosmolarity-induced up-regulation of claudin-4 mediated by NADPH oxidase-dependent H2O2 production and Sp1/c-Jun cooperation.

A. Ikari, Y. Yamazaki, J. Sugatani, 2013, Biochimica et biophysica acta.

Role of the carbohydrate moiety of phospholipase B from Penicillium notatum in enzyme activity.

J. Sugatani, T. Okumura, K. Saito, 1981, Archives of biochemistry and biophysics.

Quercetin Decreases Claudin-2 Expression Mediated by Up-Regulation of microRNA miR-16 in Lung Adenocarcinoma A549 Cells

A. Ikari, Y. Yamazaki, J. Sugatani, 2015, Nutrients.

Tight Junctional Localization of Claudin-16 Is Regulated by Syntaxin 8 in Renal Tubular Epithelial Cells*

A. Ikari, Ayumi Sanada, Chie Tonegawa, 2014, The Journal of Biological Chemistry.

Claudin-2 knockdown decreases matrix metalloproteinase-9 activity and cell migration via suppression of nuclear Sp1 in A549 cells.

A. Ikari, Y. Yamazaki, J. Sugatani, 2011, Life sciences.

Extracellular Mg(2+) regulates the tight junctional localization of claudin-16 mediated by ERK-dependent phosphorylation.

A. Ikari, Y. Yamazaki, J. Sugatani, 2010, Biochimica et biophysica acta.

Claudin‐16 is directly phosphorylated by protein kinase a independently of a vasodilator‐stimulated phosphoprotein‐mediated pathway

Midori Ito, A. Ikari, H. Sawada, 2008, Journal of cellular physiology.

Plasma platelet-activating factor acetylhydrolase deficiency is associated with atherosclerotic occlusive disease in japan.

J. Sugatani, M. Miwa, N. Unno, 2000, Journal of vascular surgery.

A single nucleotide polymorphism in the plasma PAF acetylhydrolase gene and risk of atherosclerosis in Japanese patients with peripheral artery occlusive disease.

J. Sugatani, M. Miwa, H. Konno, 2006, The Journal of surgical research.

Nuclear distribution of claudin-2 increases cell proliferation in human lung adenocarcinoma cells.

A. Ikari, Y. Yamazaki, J. Sugatani, 2014, Biochimica et biophysica acta.

Continuous binding of the PAF molecule to its receptor is necessary for the long-term aggregation of platelets.

J. Sugatani, M. Shimura, M. Miwa, 1998, The American journal of physiology.

Continuous binding of the PAF molecule to its receptor is necessary for the long-term aggregation of platelets.

J. Sugatani, M. Shimura, Yasuo Suzuki, 1998, American journal of physiology. Cell physiology.

A platelet-activating factor (PAF) receptor deficiency exacerbates diet-induced obesity but PAF/PAF receptor signaling does not contribute to the development of obesity-induced chronic inflammation.

Takao Shimizu, A. Ikari, Y. Yamazaki, 2015, Biochemical pharmacology.

Expression and Induction of Cytochromes P450 in Rat White Adipose Tissue

J. Sugatani, K. Yoshinari, M. Miwa, 2004, Journal of Pharmacology and Experimental Therapeutics.

Antiobese function of platelet‐activating factor: increased adiposity in platelet‐activating factor receptor‐deficient mice with age

Takao Shimizu, A. Ikari, Y. Yamazaki, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Comparison of enzymatically synthesized inulin, resistant maltodextrin and clofibrate effects on biomarkers of metabolic disease in rats fed a high-fat and high-sucrose (cafeteria) diet

A. Ikari, Y. Yamazaki, J. Sugatani, 2008, European journal of nutrition.

A Penicillium sp. F33 metabolite and its synthetic derivatives inhibit acetyl-CoA:1-O-alkyl-sn-glycero-3-phosphocholine acetyltransferase (a key enzyme in platelet-activating factor biosynthesis) and carrageenan-induced paw edema in mice.

T. Miyase, A. Ikari, Y. Yamazaki, 2013, Biochemical pharmacology.

The role of platelet activating factor (PAF) in the pathogenesis of gastric ulcers.

J. Sugatani, Y. Sameshima, K. Saito, 1991, Prostaglandins, leukotrienes, and essential fatty acids.

Epidermal growth factor increases clathrin‐dependent endocytosis and degradation of claudin‐2 protein in MDCK II cells

A. Ikari, J. Sugatani, Kosuke Atomi, 2011, Journal of cellular physiology.

Hypotonic Stress-induced Down-regulation of Claudin-1 and -2 Mediated by Dephosphorylation and Clathrin-dependent Endocytosis in Renal Tubular Epithelial Cells*

A. Ikari, Y. Yamazaki, J. Sugatani, 2016, The Journal of Biological Chemistry.

Down-regulation of TRPM6-mediated magnesium influx by cyclosporin A

A. Ikari, H. Sawada, J. Sugatani, 2008, Naunyn-Schmiedeberg's Archives of Pharmacology.

Association of a G994 →T Missense Mutation in the Plasma Platelet-Activating Factor Acetylhydrolase Gene With Risk of Abdominal Aortic Aneurysm in Japanese

J. Sugatani, M. Miwa, N. Unno, 2002, Annals of surgery.

Tea Polyphenols Inhibit Acetyl-CoA:1-Alkyl-sn-Glycero-3-Phosphocholine Acetyltransferase (a Key Enzyme in Platelet-Activating Factor Biosynthesis) and Platelet-Activating Factor-Induced Platelet Aggregation

H. Noguchi, J. Sugatani, K. Yoshinari, 2004, International Archives of Allergy and Immunology.

Quantitative analysis of platelet-activating factor in human plasma. Application to patients with liver cirrhosis and disseminated intravascular coagulation.

J. Sugatani, Y. Komiyama, M. Miwa, 1993, Journal of immunological methods.

Characterization of 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (AGEPC)-induced protein phosphorylation in rabbit platelets: inhibitory effects of AGEPC analogs.

J. Sugatani, D. Hanahan, 1986, Archives of biochemistry and biophysics.

Molecular heterogeneity of platelet-activating factor (PAF) in rat glandular stomach determined by gas chromatography/mass spectrometry. PAF molecular species changes upon water-immersion stress

J. Sugatani, M. Miwa, K. Satouchi, 1991, Lipids.

High-density lipoprotein inhibits the synthesis of platelet-activating factor in human vascular endothelial cells.

J. Sugatani, Y. Komiyama, M. Miwa, 1996, Journal of lipid mediators and cell signalling.

Development of a novel method for determination of acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acetyltransferase activity and its application to screening for acetyltransferase inhibitors: Inhibition by magnolol and honokiol from Magnoliae cortex

K. Umehara, J. Sugatani, M. Miwa, 1994 .

Decrease in transient receptor potential melastatin 6 mRNA stability caused by rapamycin in renal tubular epithelial cells.

A. Ikari, H. Sawada, Ayumi Sanada, 2011, Biochimica et biophysica acta.

Hyperosmolarity‐Induced Down‐Regulation of Claudin‐2 Mediated by Decrease in PKCβ‐Dependent GATA‐2 in MDCK Cells

A. Ikari, Y. Yamazaki, J. Sugatani, 2015, Journal of cellular physiology.

Inhibition of rabbit platelet aggregation by nucleoside 5'-alkylphosphates: correlation with inhibition of agonist-induced calcium influx.

J. Sugatani, T. Tanaka, K. Machida, 2000, Biochemical pharmacology.

Up‐regulation of TRPM6 transcriptional activity by AP‐1 in renal epithelial cells

A. Ikari, H. Sawada, Ayumi Sanada, 2009, Journal of cellular physiology.

Disorders in the immune responses of T- and B-cells in mice administered intravenous verotoxin 2.

J. Sugatani, M. Shimura, T. Takeda, 2000, Life sciences.

Expression of CAR in SW480 and HepG2 cells during G1 is associated with cell proliferation.

A. Ikari, Y. Yamazaki, J. Sugatani, 2008, Biochemical and biophysical research communications.

Dietary Inulin Alleviates Hepatic Steatosis and Xenobiotics-Induced Liver Injury in Rats Fed a High-Fat and High-Sucrose Diet: Association with the Suppression of Hepatic Cytochrome P450 and Hepatocyte Nuclear Factor 4α Expression

J. Sugatani, K. Yoshinari, M. Miwa, 2006, Drug Metabolism and Disposition.

Dietary inulin alleviates hepatic steatosis and xenobiotics-induced liver injury in rats fed a high-fat and high-sucrose diet: Association with the suppression of hepatic cytochrome P450 and HNF4 α expression

J. Sugatani, K. Yoshinari, M. Miwa, 2006 .

In vitro actions of some antibiotics on phospholipases.

J. Sugatani, I. Honjo, K. Saito, 1979, The Journal of antibiotics.

Relationship Between the Platelet Activating Factor Acetylhydrolase Gene and Intractability of Ulcerative Colitis

J. Sugatani, M. Miwa, T. Sakaguchi, 2002, Diseases of the colon and rectum.

Magnesium deprivation inhibits a MEK-ERK cascade and cell proliferation in renal epithelial Madin-Darby canine kidney cells.

A. Ikari, J. Sugatani, Kosuke Atomi, 2010, Life sciences.

Single nucleotide polymorphism (G994-->T) in the plasma platelet-activating factor-acetylhydrolase gene is associated with graft patency of femoropopliteal bypass.

J. Sugatani, M. Miwa, N. Unno, 2002, Surgery.

Identification of a major PAF acetylhydrolase in human serum/plasma as a 43 kDa glycoprotein containing about 9 kDa asparagine-conjugated sugar chain(s).

J. Sugatani, T. Suzuki, M. Miwa, 1998, Journal of biochemistry.

Involvement of prostaglandin E2 in rabbit corneal injury by anterior segment ischaemia.

J. Sugatani, H. Miki, M. Uyama, 1997, Prostaglandins, leukotrienes, and essential fatty acids.

Decrease in claudin‐2 expression enhances cell migration in renal epithelial madin–darby canine kidney cells

A. Ikari, J. Sugatani, Kosuke Atomi, 2011, Journal of cellular physiology.

Analysis of molecular species of phospholipids by field desorption mass spectrometry.

J. Sugatani, K. Saito, T. Matsuo, 1982, Biomedical mass spectrometry.

Characterization of prostaglandin F2 alpha production in pregnant and cycling mice.

J. Sugatani, S. Ito, K. Watanabe, 1996, Biology of reproduction.

Clathrin-dependent endocytosis of claudin-2 by DFYSP peptide causes lysosomal damage in lung adenocarcinoma A549 cells.

A. Ikari, Y. Yamazaki, J. Sugatani, 2015, Biochimica et biophysica acta.

Epidermal growth factor increases claudin-4 expression mediated by Sp1 elevation in MDCK cells.

A. Ikari, Y. Yamazaki, J. Sugatani, 2009, Biochemical and biophysical research communications.

Activation of a polyvalent cation-sensing receptor decreases magnesium transport via claudin-16.

A. Ikari, H. Sawada, Y. Yamazaki, 2008, Biochimica et biophysica acta.

Occurrence of platelet‐activating factor (PAF) in normal rat stomach and alteration of PAF level by water immersion stress

J. Sugatani, M. Miwa, Y. Sameshima, 1989, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Serum platelet-activating factor acetylhydrolase activity in rats with gastric ulcers induced by water-immersion stress.

J. Sugatani, M. Miwa, Y. Sameshima, 1989, Scandinavian journal of gastroenterology. Supplement.

Platelet-activating factor stimulation of rabbit platelets is blocked by serine protease inhibitor (chymotryptic protease inhibitor).

J. Sugatani, D. Hanahan, M. Miwa, 1987, The Journal of biological chemistry.

Cerebrovascular damage in young rabbits after intravenous administration of Shiga toxin 2

K. Arima, M. Mizuguchi, J. Sugatani, 2001, Acta Neuropathologica.

Surface localization of the nuclear receptor CAR in influenza A virus-infected cells.

A. Ikari, J. Sugatani, Tadanobu Takahashi, 2008, Biochemical and biophysical research communications.

Release of newly synthesized platelet-activating factor (PAF) from human polymorphonuclear leukocytes under in vivo conditions. Contribution of PAF-releasing factor in serum.

J. Sugatani, M. Matsumoto, M. Miwa, 1992, Journal of immunology.

PPP1R16A, The Membrane Subunit of Protein Phosphatase 1β, Signals Nuclear Translocation of the Nuclear Receptor Constitutive Active/Androstane Receptor

J. Sugatani, T. Sueyoshi, M. Negishi, 2008, Molecular Pharmacology.

The phenobarbital response enhancer module in the human bilirubin UDP‐glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR

J. Sugatani, T. Sueyoshi, M. Negishi, 2001, Hepatology.

Up‐regulation of CAR expression through Elk‐1 in HepG2 and SW480 cells by serum starvation stress

A. Ikari, Y. Yamazaki, J. Sugatani, 2009, FEBS letters.

Occurrence of an endogenous inhibitor of platelet-activating factor in rat liver.

J. Sugatani, D. Hanahan, M. Miwa, 1987, The Journal of biological chemistry.

Properties and localization of phospholipase A2 activity in rat stomach.

J. Sugatani, T. Okumura, Y. Sameshima, 1987, Biochimica et biophysica acta.

Absence of prostaglandin E2‐induced hyperalgesia in NMDA receptor ε subunit knockout mice

K. Sakimura, M. Mishina, J. Sugatani, 1997 .

Expression of Hepatic UDP-Glucuronosyltransferase 1A1 and 1A6 Correlated with Increased Expression of the Nuclear Constitutive Androstane Receptor and Peroxisome Proliferator-Activated Receptor α in Male Rats Fed a High-Fat and High-Sucrose Diets⃞

A. Ikari, J. Sugatani, S. Ikushiro, 2008, Drug Metabolism and Disposition.

Liquid ionization mass spectrometry of phospholipids.

J. Sugatani, I. Víden, K. Saito, 1986, Journal of biochemistry.

Increase in claudin-2 expression by an EGFR/MEK/ERK/c-Fos pathway in lung adenocarcinoma A549 cells.

A. Ikari, Y. Yamazaki, J. Sugatani, 2012, Biochimica et biophysica acta.

Changes in the expression of cytochromes P450 and nuclear receptors in the liver of genetically diabetic db/db mice.

J. Sugatani, K. Yoshinari, M. Miwa, 2006, Biological & pharmaceutical bulletin.

Function, genetic polymorphism, and transcriptional regulation of human UDP-glucuronosyltransferase (UGT) 1A1.

J. Sugatani, 2013, Drug metabolism and pharmacokinetics.

Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinemia.

M. Mori, J. Sugatani, T. Sueyoshi, 2002, Biochemical and biophysical research communications.

Development of a novel scintillation proximity radioimmunoassay for platelet-activating factor measurement: comparison with bioassay and GC/MS techniques.

J. Sugatani, K. Saito, K. Hughes, 1990, Life sciences.

Regulation of Pregnane X Receptor (PXR) Function and UGT1A1 Gene Expression by Posttranslational Modification of PXR Protein

A. Ikari, Y. Yamazaki, J. Sugatani, 2012, Drug Metabolism and Disposition.

Transcriptional Regulation of Human UGT1A1 Gene Expression: Activated Glucocorticoid Receptor Enhances constitutive Androstane Receptor/Pregnane X Receptor-Mediated UDP-Glucuronosyltransferase 1A1 Regulation with Glucocorticoid Receptor-Interacting Protein 1

J. Sugatani, T. Sueyoshi, M. Negishi, 2005, Molecular Pharmacology.

Transcriptional regulation of human UGT1A1 gene expression: Activated GR enhances CAR/PXR-mediated UGT1A1 regulation with GRIP1

J. Sugatani, T. Sueyoshi, M. Negishi, 2004 .

Potential involvement of vicinal sulfhydryls in stimulus-induced rabbit platelet activation.

J. Sugatani, D. Hanahan, M. Olson, 1987, The Journal of biological chemistry.

Stimulation of platelet-activating factor synthesis in polymorphonuclear leukocytes from streptozotocin-induced diabetic rats.

J. Sugatani, M. Naka, S. Akiba, 1995, Journal of biochemistry.

Activation of coagulation in C57BL/6 mice given verotoxin 2 (VT2) and the effect of co-administration of LPS with VT2.

J. Sugatani, Y. Komiyama, H. Takahashi, 2000, Thrombosis research.

Transcriptional regulation of human UGT1A1 gene expression through distal and proximal promoter motifs: implication of defects in the UGT1A1 gene promoter

M. Mori, A. Ikari, J. Sugatani, 2008, Naunyn-Schmiedeberg's Archives of Pharmacology.

Urinary concentrating defect in rats given Shiga toxin: elevation in urinary AQP2 level associated with polyuria.

J. Sugatani, D. Miyamoto, M. Miwa, 2002, Life sciences.

Hormonal regulation of prostaglandin F2 alpha receptor gene expression in mouse ovary.

J. Sugatani, T. Houtani, T. Sugimoto, 1996, The American journal of physiology.

A polymorphism in plasma platelet-activating factor acetylhydrolase is involved in resistance to immunoglobulin treatment in Kawasaki disease.

Norishige Yoshikawa, J. Sugatani, N. Yoshikawa, 2005, The Journal of pediatrics.

Threonine-290 Regulates Nuclear Translocation of the Human Pregnane X Receptor through Its Phosphorylation/Dephosphorylation by Ca2+/Calmodulin-Dependent Protein Kinase II and Protein Phosphatase 1

A. Ikari, Y. Yamazaki, J. Sugatani, 2014, Drug Metabolism and Disposition.

Phospholipase B from Penicillium notatum.

J. Sugatani, T. Okumura, K. Saito, 1991, Methods in enzymology.

Enhancement of cell–cell contact by claudin‐4 in renal epithelial madin‐darby canine kidney cells

A. Ikari, Y. Yamazaki, J. Sugatani, 2012, Journal of cellular biochemistry.

Auditory pathway and auditory brainstem response in mice lacking NMDA receptor ϵ1 and ϵ4 subunits

M. Mishina, J. Sugatani, R. Altschuler, 1998, Neuroscience Letters.

Auditory pathway and auditory brainstem response in mice lacking NMDA receptor epsilon 1 and epsilon 4 subunits.

K. Sato, M. Mishina, J. Sugatani, 1998, Neuroscience Letters.

The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics.

I. Abe, H. Noguchi, J. Sugatani, 2004, Biochemical pharmacology.

Dysfunction of paracellin-1 by dephosphorylation in Dahl salt-sensitive hypertensive rats.

A. Ikari, J. Sugatani, K. Takagi, 2006, The journal of physiological sciences : JPS.

Regulation of the human UGT1A1 gene by nuclear receptors constitutive active/androstane receptor, pregnane X receptor, and glucocorticoid receptor.

J. Sugatani, T. Sueyoshi, M. Negishi, 2005, Methods in enzymology.

Effects of dietary inulin, statin, and their co-treatment on hyperlipidemia, hepatic steatosis and changes in drug-metabolizing enzymes in rats fed a high-fat and high-sucrose diet

A. Ikari, Y. Yamazaki, J. Sugatani, 2012, Nutrition & Metabolism.

The role of endogenous platelet-activating factor in the stomach.

J. Sugatani, Yasuo Suzuki, M. Miwa, 1992 .

Claudin-18 inhibits cell proliferation and motility mediated by inhibition of phosphorylation of PDK1 and Akt in human lung adenocarcinoma A549 cells.

A. Ikari, Y. Yamazaki, J. Sugatani, 2016, Biochimica et biophysica acta.

Rupert Timpl – A Personal Account

H. Noguchi, J. Kira, M. Bardella, 2004, International Archives of Allergy and Immunology.

Molecular relationship between two types of phospholipase B from Penicillium notatum and reconstitution of active enzyme from its peptide fragments.

J. Sugatani, T. Okumura, K. Saito, 1987, Archives of biochemistry and biophysics.

Physicochemical characterization and biological effects of inulin enzymatically synthesized from sucrose.

J. Sugatani, M. Miwa, T. Wada, 2005, Journal of agricultural and food chemistry.