Laureen C. Colis

发表

Identification of Novel p53 Pathway Activating Small-Molecule Compounds Reveals Unexpected Similarities with Known Therapeutic Agents

Karita Peltonen, K. Peltonen, M. Laiho, 2010, PloS one.

Specific and efficient binding of xeroderma pigmentosum complementation group A to double-strand/single-strand DNA junctions with 3'- and/or 5'-ssDNA branches.

Y. Zou, Laureen C. Colis, P. Musich, 2006, Biochemistry.

Mechanism of action studies of lomaiviticin A and the monomeric lomaiviticin aglycon. Selective and potent activity toward DNA double-strand break repair-deficient cell lines.

P. Glazer, Laureen C. Colis, D. Hegan, 2015, Journal of the American Chemical Society.

Design, Synthesis, and Structure–Activity Relationships of Pyridoquinazolinecarboxamides as RNA Polymerase I Inhibitors

J. Barrow, K. Peltonen, M. Laiho, 2014, Journal of medicinal chemistry.

DNA intercalator BMH-21 inhibits RNA polymerase I independent of DNA damage response

J. Barrow, K. Peltonen, M. Laiho, 2014, Oncotarget.

Proteasome Activity Influences UV-Mediated Subnuclear Localization Changes of NPM

Baoyan Bai, K. Peltonen, M. Laiho, 2013, PloS one.

Specific and Efficient Binding of XPA to Double-strand/Single-strand DNA Junctions with 3 ′ - and/or 5 ′ -ssDNA Branches

Y. Zou, Laureen C. Colis, P. Musich, 2008 .

Synthesis of N2 2'-deoxyguanosine adducts formed by 1-nitropyrene.

Laureen C. Colis, A. Basu, D. Chakraborti, 2003, Organic letters.

Synergistic potentiation of (-)-lomaiviticin A cytotoxicity by the ATR inhibitor VE-821.

Laureen C. Colis, S. Herzon, 2016, Bioorganic & medicinal chemistry letters.

The cytotoxicity of (–)-lomaiviticin A arises from induction of double-strand breaks in DNA

P. Glazer, Laureen C. Colis, D. Hegan, 2014, Nature chemistry.

A targeting modality for destruction of RNA polymerase I that possesses anticancer activity.

C. Bieberich, Baoyan Bai, K. Peltonen, 2014, Cancer cell.

Recognition and incision of gamma-radiation-induced cross-linked guanine-thymine tandem lesion G[8,5-Me]T by UvrABC nuclease.

Y. Zou, Laureen C. Colis, Zhengguan Yang, 2005, Chemical research in toxicology.

Small Molecule BMH-Compounds That Inhibit RNA Polymerase I and Cause Nucleolar Stress

K. Peltonen, M. Laiho, S. Jäämaa, 2014, Molecular Cancer Therapeutics.

Mutational Specificity of γ-Radiation-Induced Guanine−Thymine and Thymine−Guanine Intrastrand Cross-Links in Mammalian Cells and Translesion Synthesis Past the Guanine−Thymine Lesion by Human DNA Polymerase η

Laureen C. Colis, A. Basu, P. Raychaudhury, 2008, Biochemistry.

Synthesis of Oligonucleotides Containing 2′-Deoxyguanosine Adducts of Nitropyrenes

Laureen C. Colis, A. Basu, Pablo Hilario, 2009, Nucleosides, nucleotides & nucleic acids.

Bithionol Potently Inhibits Human Soluble Adenylyl Cyclase through Binding to the Allosteric Activator Site*

Laureen C. Colis, C. Steegborn, J. van den Heuvel, 2016, The Journal of Biological Chemistry.

Design, Synthesis, and Structure−Activity Relationships of Pyridoquinazolinecarboxamides as RNA Polymerase I Inhibitors

J. Barrow, K. Peltonen, M. Laiho, 2014 .

Synthesis and Biological Evaluation of (2S,2'S)-Lomaiviticin A.

Laureen C. Colis, S. Herzon, M. Kaneko, 2021, Journal of the American Chemical Society.