G. Santoni

G. Santoni, C. Amantini, A. Bianchi, 2011, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

ICOS-L as a Potential Therapeutic Target for Cancer Immunotherapy.

G. Santoni, C. Amantini, M. Nabissi, 2018, Current protein & peptide science.

Thiorphan-Induced Survival and Proliferation of Rat Thymocytes by Activation of Akt/Survivin Pathway and Inhibition of Caspase-3 Activity

G. Santoni, C. Amantini, M. Mosca, 2008, Journal of Pharmacology and Experimental Therapeutics.

Emerging Role of Mucolipins TRPML Channels in Cancer

G. Santoni, M. Santoni, M. Morelli, 2020, Frontiers in Oncology.

TRPV1 (transient receptor potential cation channel, subfamily V, member 1)

G. Santoni, M. Nabissi, 2012 .

High CTLA-4 expression correlates with poor prognosis in thymoma patients

G. Bernardini, G. Santoni, C. Amantini, 2018, Oncotarget.

Novel antitumor copper(II) complexes designed to act through synergistic mechanisms of action, due to the presence of an NMDA receptor ligand and copper in the same chemical entity

G. Santoni, C. Amantini, E. Marcantoni, 2018 .

Thyme extract increases mucociliary-beating frequency in primary cell lines from chronic obstructive pulmonary disease patients.

G. Santoni, C. Amantini, M. Nabissi, 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Expression Profiling of Circulating Tumor Cells in Pancreatic Ductal Adenocarcinoma Patients: Biomarkers Predicting Overall Survival

G. Santoni, C. Amantini, F. Bianchi, 2019, Front. Oncol..

Expression and function of the transient receptor potential ion channel family in the hematologic malignancies.

G. Santoni, C. Amantini, M. Santoni, 2013, Current molecular pharmacology.

TRP channels and cancer: new targets for diagnosis and chemotherapy.

G. Santoni, V. Farfariello, Valerio Farfariello, 2011, Endocrine, metabolic & immune disorders drug targets.

Neonatal Capsaicin Treatment Affects Rat Thymocyte Proliferation and Cell Death by Modulating Substance P and Neurokinin-1 Receptor Expression

G. Santoni, C. Amantini, P. Pompei, 2004, Neuroimmunomodulation.

Neurokinin type-1 receptor antagonist inhibits enhancement of T cell functions by substance P in normal and neuromanipulated capsaicin-treated rats

G. Santoni, S. Romagnoli, E. Spreghini, 1999, Journal of Neuroimmunology.

Capsaicin-induced inhibition of mitogen and interleukin-2-stimulated T cell proliferation: its reversal by in vivo substance P administration

G. Santoni, M. Perfumi, M. Piccoli, 1996, Journal of Neuroimmunology.

Onabotulinumtoxin-A intradetrusorial injections modulate bladder expression of NGF, TrkA, p75 and TRPV1 in patients with detrusor overactivity.

G. Santoni, C. Amantini, V. Nardicchi, 2013, Pharmacological research.

Differentiation response of acute promyelocytic leukemia cells and PML/RARα leukemogenic activity studies by real-time RT-PCR

S. Minucci, P. Pelicci, G. Santoni, 2005, Molecular biotechnology.

Aniseed (Pimpinella anisum L.) essential oil reduces pro-inflammatory cytokines and stimulates mucus secretion in primary airway bronchial and tracheal epithelial cell lines

G. Santoni, C. Amantini, M. Nabissi, 2018 .

Structure-activity relationships in 1,4-benzodioxan-related compounds. 11. (1) reversed enantioselectivity of 1,4-dioxane derivatives in α1-adrenergic and 5-HT1A receptor binding sites recognition.

G. Santoni, C. Amantini, Alessandro Bonifazi, 2013, Journal of medicinal chemistry.

Endothelial Cell Line to Vitronectin and the Ea.hy 926 Human Phosphorylation upon Yeast Cell Adhesion Undergoes Increased Tyrosine Adhesion Kinase-like Protein That Expresses a Focal Candida Albicans

G. Santoni, C. Amantini, J. Jacobelli, 2002 .

Protective role of antimannan and anti-aspartyl proteinase antibodies in an experimental model of Candida albicans vaginitis in rats

G. Santoni, A. Cassone, F. De bernardis, 1997, Infection and immunity.

An alpha 5 beta 1-like integrin receptor mediates the binding of less pathogenic Candida species to fibronectin.

G. Santoni, J. Djeu, A. Gamero, 1995, Journal of medical microbiology.

Rats clearing a vaginal infection by Candida albicans acquire specific, antibody-mediated resistance to vaginal reinfection

G. Santoni, A. Cassone, F. De bernardis, 1995, Infection and immunity.

Involvement of αvβ3 integrin-like receptor and glycosaminoglycans in Candida albicans germ tube adhesion to vitronectin and to a human endothelial cell line

G. Santoni, C. Amantini, E. Spreghini, 2001 .

Enhancement of lymphocyte proliferation and IL-2 receptor expression by a processed form (GM-1/P) of monosialoganglioside GM-1.

L. Frati, G. Santoni, A. Punturieri, 1990, Immunopharmacology and immunotoxicology.

Highly Potent and Selective Dopamine D4 Receptor Antagonists Potentially Useful for the Treatment of Glioblastoma

L. Ricci-Vitiani, R. Pallini, G. Vistoli, 2022, Journal of medicinal chemistry.

Evaluation of anti-inflammatory and immunoregulatory activities of Stimunex® and Stimunex D3® in human monocytes/macrophages stimulated with LPS or IL-4/IL-13.

G. Santoni, M. Nabissi, F. Maggi, 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Capsaicin‐induced apoptosis of glioma cells is mediated by TRPV1 vanilloid receptor and requires p38 MAPK activation

G. Santoni, C. Amantini, F. Giangaspero, 2007, Journal of neurochemistry.

Capsaicin triggers autophagic cell survival which drives epithelial mesenchymal transition and chemoresistance in bladder cancer cells in an Hedgehog-dependent manner

G. Santoni, C. Amantini, M. Santoni, 2016, Oncotarget.

Anticandidal Immunity and Vaginitis: Novel Opportunities for Immune Intervention

G. Santoni, A. Cassone, F. De bernardis, 2007, Infection and Immunity.

Antonio Cassone , Flavia De Bernardis and Giorgio Santoni Opportunities for Immune Intervention Anticandidal Immunity and Vaginitis : Novel

G. Santoni, A. Cassone, F. Bernardis, 2007 .

The effects of cannabidiol via TRPV2 channel in chronic myeloid leukemia cells and its combination with imatinib

G. Santoni, C. Amantini, D. Tomassoni, 2021, Cancer science.

Adhesion and activation molecules expressed by human natural killer cells

L. Frati, G. Santoni, A. Santoni, 1991, Cytotechnology.

Prenatal exposure to cypermethrin modulates rat NK cell cytotoxic functions.

G. Santoni, S. Romagnoli, M. Piccoli, 1997, Toxicology.

In vivo capsaicin treatment inhibits rat NK cell cytotoxic functions.

G. Santoni, M. Perfumi, M. Piccoli, 1995, Immunopharmacology and immunotoxicology.

Effects of cadmium on cytotoxic functions of human natural killer cells.

G. Santoni, A. Santoni, C. Festuccia, 1991, Toxicology in vitro : an international journal published in association with BIBRA.

Inhibition of NK cell generation by Corynebacterium parvum.

L. Frati, G. Santoni, A. Santoni, 1991, Immunopharmacology and immunotoxicology.

Augmentation of mouse natural killer (NK) activity by GM-1/P, a processed form of monosialoganglioside GM-1.

L. Frati, G. Santoni, A. Santoni, 1990, Immunopharmacology and immunotoxicology.

Coexpression of TRPML1 and TRPML2 Mucolipin Channels Affects the Survival of Glioblastoma Patients

G. Santoni, C. Amantini, M. Santoni, 2022, International journal of molecular sciences.

Calcium Signaling and the Regulation of Chemosensitivity in Cancer Cells: Role of the Transient Receptor Potential Channels.

G. Santoni, C. Amantini, M. Santoni, 2020, Advances in experimental medicine and biology.

Effect of tributyltin on trout blood cells: changes in mitochondrial morphology and functionality.

G. Santoni, Luca Tiano, D. Fedeli, 2003, Biochimica et biophysica acta.

Characterization of Corynebacterium parvum-induced suppressor cells of mouse NK and ADCC activity.

L. Frati, G. Santoni, A. Santoni, 1990, Immunopharmacology and immunotoxicology.

Isofuranodiene synergizes with temozolomide in inducing glioma cells death.

G. Santoni, C. Amantini, M. Nabissi, 2019, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Axitinib induces senescence-associated cell death and necrosis in glioma cell lines: The proteasome inhibitor, bortezomib, potentiates axitinib-induced cytotoxicity in a p21(Waf/Cip1) dependent manner

G. Bernardini, G. Santoni, C. Amantini, 2016, Oncotarget.

Ebselen prevents mitochondrial ageing due to oxidative stress: in vitro study of fish erythrocytes.

G. Santoni, Luca Tiano, D. Fedeli, 2003, Mitochondrion.

Human NK Cells Express on Cell Surface an Integrin Structure Which Mediate Their Adhesion to Fibronectin1

L. Frati, G. Santoni, A. Santoni, 1990 .

Role of the NMDA Receptor in the Antitumor Activity of Chiral 1,4-Dioxane Ligands in MCF-7 and SKBR3 Breast Cancer Cells.

G. Santoni, C. Amantini, Alessandro Bonifazi, 2019, ACS medicinal chemistry letters.

Cannabidiol stimulates Aml‐1a‐dependent glial differentiation and inhibits glioma stem‐like cells proliferation by inducing autophagy in a TRPV2‐dependent manner

L. Ricci-Vitiani, R. Pallini, G. Santoni, 2015, International journal of cancer.

Exploring treatment with Ribociclib alone or in sequence/combination with Everolimus in ER+HER2−Rb wild-type and knock-down in breast cancer cell lines

G. Santoni, C. Amantini, M. Santoni, 2020, BMC Cancer.

Unveiling the Molecular Mechanisms Driving the Capsaicin-Induced Immunomodulatory Effects on PD-L1 Expression in Bladder and Renal Cancer Cell Lines

G. Santoni, C. Amantini, M. Santoni, 2022, Cancers.

In vivo cadmium treatment alters natural killer activity and large granular lymphocyte number in the rat.

G. Santoni, A. Santoni, E. Alesse, 1989, Immunopharmacology.

TRPML2 Mucolipin Channels Drive the Response of Glioma Stem Cells to Temozolomide and Affect the Overall Survival in Glioblastoma Patients

L. Ricci-Vitiani, R. Pallini, G. Santoni, 2022, International journal of molecular sciences.

The protozoan toxin climacostol inhibits growth and induces apoptosis of human tumor cell lines.

G. Santoni, C. Amantini, L. Quassinti, 2008, Chemico-biological interactions.

Local Anticandidal Immune Responses in a Rat Model of Vaginal Infection by and Protection against Candida albicans

G. Santoni, A. Cassone, F. De bernardis, 2000, Infection and Immunity.

CXC and CC Chemokines as Angiogenic Modulators in Nonhaematological Tumors

G. Tortora, G. Santoni, S. Cascinu, 2014, BioMed research international.

TRPV channels in tumor growth and progression.

G. Santoni, C. Amantini, Giorgio Santoni, 2011, Advances in experimental medicine and biology.

Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents.

G. Santoni, M. Santoni, M. Nabissi, 2013, Carcinogenesis.

Re: Human Chimeric Antigen Receptor Macrophages for Cancer Immunotherapy.

R. Montironi, G. Santoni, A. Cimadamore, 2021, European urology.

Emerging role of tumor-associated macrophages as therapeutic targets in patients with metastatic renal cell carcinoma

R. Montironi, G. Tortora, G. Santoni, 2013, Cancer Immunology, Immunotherapy.

Capsaicin promotes a more aggressive gene expression phenotype and invasiveness in null-TRPV1 urothelial cancer cells.

G. Santoni, C. Amantini, M. Santoni, 2011, Carcinogenesis.

Mangiferin blocks proliferation and induces apoptosis of breast cancer cells via suppression of the mevalonate pathway and by proteasome inhibition.

G. Santoni, M. Mozzicafreddo, M. Angeletti, 2016, Food & function.

Pazopanib and sunitinib trigger autophagic and non-autophagic death of bladder tumour cells

G. Santoni, C. Amantini, R. Berardi, 2013, British Journal of Cancer.

Transient Receptor Potential (TRP) Channels in Haematological Malignancies: An Update

G. Santoni, C. Amantini, M. Nabissi, 2021, Biomolecules.

New Insight on the Role of Transient Receptor Potential (TRP) Channels in Driven Gliomagenesis Pathways

G. Santoni, C. Amantini, M. Santoni, 2011 .

Transient Receptor Potential Vanilloid 1 ( TRPV 1 ) activation induces autophagy in thymocytes through ROS-regulated AMPK and Atg 4 C pathways ”

G. Santoni, A. Santoni, V. Farfariello, 2012 .

Transient Receptor Potential Cation Channels in Cancer Therapy

G. Santoni, M. Santoni, M. Morelli, 2019, Medical sciences.

Essential role of Gli proteins in glioblastoma multiforme.

G. Santoni, R. Berardi, S. Cascinu, 2013, Current protein & peptide science.

ERK Phosphorylation Regulates the Aml1/Runx1 Splice Variants and the TRP Channels Expression during the Differentiation of Glioma Stem Cell Lines

L. Ricci-Vitiani, R. Pallini, G. Santoni, 2021, Cells.

Role of Death Receptors Belonging to the TNF Family in Capsaicin-Induced Apoptosis of Tumor Cells

G. Santoni, C. Amantini, V. Farfariello, 2013 .

Cannabinoids synergize with carfilzomib, reducing multiple myeloma cells viability and migration

G. Santoni, C. Amantini, M. Nabissi, 2016, Oncotarget.

Pathophysiological Role of Transient Receptor Potential Mucolipin Channel 1 in Calcium-Mediated Stress-Induced Neurodegenerative Diseases

G. Santoni, C. Amantini, M. Nabissi, 2020, Frontiers in Physiology.

Involvement of p53 in phthalate effects on mouse and rat osteoblasts

M. Sabbieti, D. Agas, L. Marchetti, 2009, Journal of cellular biochemistry.

Cannabidiol and Oxygen-Ozone Combination Induce Cytotoxicity in Human Pancreatic Ductal Adenocarcinoma Cell Lines

G. Santoni, C. Amantini, M. Nabissi, 2020, Cancers.

Functional role of T‐type calcium channels in tumour growth and progression: prospective in cancer therapy

G. Santoni, M. Santoni, M. Nabissi, 2012, British journal of pharmacology.

MicroRNA Signature Targeting Transient Receptor Potential Channels in the Prognosis and Therapy of Cancer

G. Santoni, C. Amantini, M. Nabissi, 2020 .

Targeting Transient Receptor Potential Channels by MicroRNAs Drives Tumor Development and Progression.

G. Santoni, C. Amantini, M. Santoni, 2019, Advances in experimental medicine and biology.

Emerging strategies to overcome the resistance to current mTOR inhibitors in renal cell carcinoma.

G. Santoni, C. Amantini, G. Tonini, 2014, Biochimica et biophysica acta.

Progress of Molecular Targeted Therapies for Advanced Renal Cell Carcinoma

G. Santoni, C. Amantini, R. Berardi, 2013, BioMed research international.

Cross-talk between microRNAs, long non-coding RNAs and p21Cip1 in glioma: diagnostic, prognostic and therapeutic roles

G. Santoni, C. Amantini, M. Santoni, 2020 .

Correlation between High PD-L1 and EMT/Invasive Genes Expression and Reduced Recurrence-Free Survival in Blood-Circulating Tumor Cells from Patients with Non-Muscle-Invasive Bladder Cancer

R. Montironi, G. Santoni, C. Amantini, 2021, Cancers.

Urinary Markers in Bladder Cancer: An Update

G. Santoni, C. Amantini, M. Morelli, 2018, Front. Oncol..

Cypermethrin-induced alteration of thymocyte distribution and functions in prenatally-exposed rats.

G. Santoni, S. Romagnoli, E. Spreghini, 1998, Toxicology.

Loss of TRPV2 Homeostatic Control of Cell Proliferation Drives Tumor Progression

G. Santoni, C. Amantini, S. Cascinu, 2014, Cells.

Post-transcriptional regulation of 5'-untranslated regions of human Transient Receptor Potential Vanilloid type-1 (TRPV-1) channels: role in the survival of glioma patients

G. Bernardini, G. Santoni, C. Amantini, 2016, Oncotarget.

Clinical impact of different exosomes’ protein expression in pancreatic ductal carcinoma patients treated with standard first line palliative chemotherapy

G. Santoni, C. Amantini, F. Bianchi, 2019, PloS one.

TRPV2 channel negatively controls glioma cell proliferation and resistance to Fas-induced apoptosis in ERK-dependent manner.

L. Ricci-Vitiani, G. Santoni, C. Amantini, 2010, Carcinogenesis.

The functional VNTR MNS16A of the TERT gene is associated with human longevity in a population of Central Italy

V. Napolioni, G. Santoni, G. Passarino, 2013, Experimental Gerontology.

Triggering of transient receptor potential vanilloid type 1 (TRPV1) by capsaicin induces Fas/CD95-mediated apoptosis of urothelial cancer cells in an ATM-dependent manner.

G. Santoni, C. Amantini, M. Nabissi, 2009, Carcinogenesis.

Toll like receptors and pancreatic diseases: From a pathogenetic mechanism to a therapeutic target.

G. Santoni, S. Cascinu, M. Santoni, 2015, Cancer treatment reviews.

Biological Function of PD-L2 and Correlation With Overall Survival in Type II Endometrial Cancer

F. Amant, G. Santoni, C. Amantini, 2020, Frontiers in Oncology.

Comparison and optimization of transient transfection methods at human astrocytoma cell line 1321N1.

G. Marucci, M. Buccioni, G. Santoni, 2011, Analytical biochemistry.

Candida albicans expresses a fibronectin receptor antigenically related to alpha 5 beta 1 integrin.

L. Frati, G. Santoni, A. Santoni, 1994, Microbiology.

Danger- and pathogen-associated molecular patterns recognition by pattern-recognition receptors and ion channels of the transient receptor potential family triggers the inflammasome activation in immune cells and sensory neurons

G. Santoni, C. Amantini, M. Nabissi, 2015, Journal of Neuroinflammation.

New deals on the transcriptional and post-transcriptional regulation of TRP channel target genes during the angiogenesis of glioma

G. Santoni, M. Santoni, M. Nabissi, 2011 .

Laminin synthesis by NK cells and modulation of its expression by TPA (12-O-tetradecanoylphorbol-13-acetate).

R. Testi, L. Frati, G. Santoni, 1989, Experimental cell research.

Actions and Regulation of Ionotropic Cannabinoid Receptors.

G. Santoni, A. Ligresti, L. De Petrocellis, 2017, Advances in pharmacology.

Antioncogenic Effects of Transient Receptor Potential Vanilloid 1 in the Progression of Transitional Urothelial Cancer of Human Bladder

G. Santoni, C. Amantini, A. Gismondi, 2012, ISRN urology.

The Transient Receptor Potential Vanilloid Type-2 (TRPV2) Ion Channels in Neurogenesis and Gliomagenesis: Cross-Talk between Transcription Factors and Signaling Molecules

G. Santoni, C. Amantini, 2019, Cancers.

The transient receptor potential vanilloid‐2 cation channel impairs glioblastoma stem‐like cell proliferation and promotes differentiation

L. Ricci-Vitiani, R. Pallini, L. Larocca, 2012, International journal of cancer.

Distinct thymocyte subsets express the vanilloid receptor VR1 that mediates capsaicin-induced apoptotic cell death

G. Santoni, C. Amantini, M. Mosca, 2004, Cell Death and Differentiation.

Locoregional IL-2 immunotherapy of bladder cancer.

G. Santoni, A. Santoni, F. Velotti, 1997, Immunopharmacology and immunotoxicology.

Cadmium inhibits spontaneous (NK), antibody-mediated (ADCC) and IL-2-stimulated cytotoxic functions of natural killer cells.

G. Santoni, A. Santoni, A. Procopio, 1990, Immunopharmacology.

The Controversial Role of PD-1 and Its Ligands in Gynecological Malignancies

F. Amant, G. Santoni, C. Amantini, 2019, Front. Oncol..

Structure-activity relationships in 1,4-benzodioxan-related compounds. 8.(1) {2-[2-(4-chlorobenzyloxy)phenoxy]ethyl}-[2-(2,6-dimethoxyphenoxy)ethyl]amine (clopenphendioxan) as a tool to highlight the involvement of alpha1D- and alpha1B-adrenoreceptor subtypes in the regulation of human PC-3 prostate

Mario Giannella, Alessandro Piergentili, Wilma Quaglia, 2005, Journal of medicinal chemistry.

Effects of cadmium on lymphocyte activation.

G. Santoni, A. Santoni, A. Procopio, 1989, Biochimica et Biophysica Acta.

Chemical manipulations on the 1,4-dioxane ring of 5-HT1A receptor agonists lead to antagonists endowed with antitumor activity in prostate cancer cells.

A. Cilia, G. Vistoli, G. Santoni, 2019, European journal of medicinal chemistry.

The effects of cannabidiol and its synergism with bortezomib in multiple myeloma cell lines. A role for transient receptor potential vanilloid type‐2

F. Alesiani, G. Santoni, M. Santoni, 2014, International journal of cancer.

Involvement of the TRPML Mucolipin Channels in Viral Infections and Anti-viral Innate Immune Responses

G. Santoni, C. Amantini, A. Santoni, 2020, Frontiers in Immunology.

Novel highly potent and selective sigma 1 receptor antagonists related to spipethiane.

Mario Giannella, Alessandro Piergentili, Wilma Quaglia, 2010, Journal of medicinal chemistry.

Epigenetic, Genetic, and Acquired Regulation of Cav3 T-Type Calcium Channel Expression and Function in Tumor Growth and Progression

G. Santoni, C. Amantini, M. Santoni, 2014 .

Calcium influx, oxidative stress, and apoptosis induced by TRPV1 in chronic myeloid leukemia cells: Synergistic effects with imatinib

G. Santoni, C. Amantini, C. Polidori, 2023, Frontiers in Molecular Biosciences.

Transient receptor potential vanilloid 1 activation induces autophagy in thymocytes through ROS‐regulated AMPK and Atg4C pathways

G. Santoni, C. Amantini, V. Farfariello, 2012, Journal of leukocyte biology.

Mechanosensation and Mechanotransduction in Natural Killer Cells

G. Santoni, C. Amantini, A. Santoni, 2021, Frontiers in Immunology.

Role of natural and adaptive immunity in renal cell carcinoma response to VEGFR‐TKIs and mTOR inhibitor

G. Santoni, C. Amantini, R. Berardi, 2014, International journal of cancer.

The TRPV2 cation channels: from urothelial cancer invasiveness to glioblastoma multiforme interactome signature

G. Santoni, C. Amantini, M. Santoni, 2019, Laboratory Investigation.

Transient receptor potential vanilloid type 2 (TRPV2) expression in normal urothelium and in urothelial carcinoma of human bladder: correlation with the pathologic stage.

G. Santoni, C. Amantini, M. Nabissi, 2008, European urology.

The Mucolipin TRPML2 Channel Enhances the Sensitivity of Multiple Myeloma Cell Lines to Ibrutinib and/or Bortezomib Treatment

G. Santoni, C. Amantini, M. Santoni, 2022, Biomolecules.

“Immuno-Transient Receptor Potential Ion Channels”: The Role in Monocyte- and Macrophage-Mediated Inflammatory Responses

G. Santoni, C. Amantini, A. Santoni, 2018, Front. Immunol..

Impairment of rat thymocyte differentiation and functions by neonatal capsaicin treatment is associated with induction of apoptosis

G. Santoni, E. Spreghini, P. Pompei, 2000, Journal of Neuroimmunology.

Knock-Down of Mucolipin 1 Channel Promotes Tumor Progression and Invasion in Human Glioblastoma Cell Lines

G. Santoni, C. Amantini, M. Santoni, 2021, Frontiers in Oncology.

Resiniferatoxin induces death of bladder cancer cells associated with mitochondrial dysfunction and reduces tumor growth in a xenograft mouse model.

G. Santoni, C. Amantini, M. Santoni, 2014, Chemico-biological interactions.

Structure-activity relationships in 1,4-benzodioxan-related compounds. 9. From 1,4-benzodioxane to 1,4-dioxane ring as a promising template of novel alpha1D-adrenoreceptor antagonists, 5-HT1A full agonists, and cytotoxic agents.

G. Santoni, C. Amantini, F. Del Bello, 2008, Journal of medicinal chemistry.

Cooperative Interaction between the Alpha1-Adrenoceptors (ÃÂ±1-AR) andTransient Receptor Potential (TRP) Triggers a Proliferative Cell Signal inProstate Cancer Cell Lines

Aless, G. Santoni, C. Amantini, 2015 .

Cross-talk between alpha1D-adrenoceptors and transient receptor potential vanilloid type 1 triggers prostate cancer cell proliferation

Alessandro Piergentili, Wilma Quaglia, Alessandro Bonifazi, 2014, BMC Cancer.

Expression of transient receptor potential vanilloid‐1 (TRPV1) in urothelial cancers of human bladder: relation to clinicopathological and molecular parameters

G. Santoni, C. Amantini, M. Nabissi, 2010, Histopathology.

Overexpression of transient receptor potential mucolipin-2 ion channels in gliomas: role in tumor growth and progression

G. Santoni, C. Amantini, A. Santoni, 2016, Oncotarget.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

G. Santoni, C. Amantini, M. Santoni, 2015, Journal of Neuroinflammation.

Role of Clock Genes and Circadian Rhythm in Renal Cell Carcinoma: Recent Evidence and Therapeutic Consequences

E. Lam, G. Santoni, S. Buti, 2023, Cancers.

A3 Adenosine Receptor Antagonists with Nucleoside Structures and Their Anticancer Activity

G. Marucci, M. Buccioni, G. Santoni, 2022, Pharmaceuticals.

A 3 Adenosine Receptor Antagonists with Nucleoside Structures and Their Anticancer Activity

G. Marucci, M. Buccioni, G. Santoni, 2022 .

The role of transient receptor potential vanilloid type-2 ion channels in innate and adaptive immune responses

G. Santoni, C. Amantini, M. Santoni, 2013, Front. Immun..

1,4-Benzodioxane to 1,4-Dioxane Ring as a Promising Template of Novel r1D-Adrenoreceptor Antagonists, 5-HT1A Full Agonists, and Cytotoxic Agents †

G. Santoni, C. Amantini, M. Giannella, 2008 .

Effect of sunitinib and pazopanib on necrosis and autophagic cell death in cancer cells: Role of cathepsin B.

G. Santoni, C. Amantini, R. Berardi, 2013 .

Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652

Lee, Duchen, Izzo, 2016 .

Exploring treatment with Ribociclib alone or in sequence/combination with Everolimus in ER+HER2−Rb wild-type and knock-down in breast cancer cell lines

G. Santoni, C. Amantini, M. Santoni, 2020, BMC cancer.

Expression of Substance P and Its Neurokinin-1 Receptor on Thymocytes: Functional Relevance in the Regulation of Thymocyte Apoptosis and Proliferation

G. Santoni, C. Amantini, M. Nabissi, 2003, Neuroimmunomodulation.

De Bernardis, F. et al. Protective role of anti-mannan and anti-aspartyl proteinase antibodies in an experimental model of Candida albicans vaginitis in rats. Infect. Immun. 65, 3399-3405

G. Santoni, E. Spreghini, M. Boccanera, 1997 .

Protection against rat vaginal candidiasis by adoptive transfer of vaginal B lymphocytes.

G. Santoni, C. Amantini, F. De bernardis, 2010, FEMS yeast research.

Axitinib induces DNA damage response leading to senescence, mitotic catastrophe, and increased NK cell recognition in human renal carcinoma cells

G. Santoni, C. Amantini, A. Santoni, 2015, Oncotarget.

Present and future of tyrosine kinase inhibitors in renal cell carcinoma: analysis of hematologic toxicity.

G. Santoni, R. Berardi, S. Cascinu, 2012, Recent patents on anti-infective drug discovery.

Emerging Role of TRPML1 Mucolipin Endolysosomal Channel in Cancer

G. Santoni, C. Amantini, M. Santoni, 2020 .

Synthesis and biological evaluation of indazolo[4,3-bc][1,5]naphthyridines (10-aza-pyrazolo[3,4,5-kl]acridines): a new class of antitumor agents.

G. Santoni, C. Amantini, I. Antonini, 2004, Bioorganic & medicinal chemistry.

Structure-Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles.

Dominik Dolles, Hans-Joachim Wittmann, A. Strasser, 2018, Journal of medicinal chemistry.

Advances in transient receptor potential vanilloid-2 channel expression and function in tumor growth and progression.

G. Santoni, C. Amantini, M. Santoni, 2014, Current protein & peptide science.

Thiorphan-Induced Survival and Proliferation of Rat Thymocytes by Activation of Akt/Survivin Pathway and Inhibition of Caspase-3 Activity

G. Santoni, C. Amantini, M. Mosca, 2008, Journal of Pharmacology and Experimental Therapeutics.

Triggering of the TRPV2 channel by cannabidiol sensitizes glioblastoma cells to cytotoxic chemotherapeutic agents.

G. Santoni, M. Santoni, M. Nabissi, 2013, Carcinogenesis.

Involvement of alpha(v)beta3 integrin-like receptor and glycosaminoglycans in Candida albicans germ tube adhesion to vitronectin and to a human endothelial cell line.

G. Santoni, C. Amantini, E. Spreghini, 2001, Microbial pathogenesis.

IL‐22 mRNA in peripheral blood mononuclear cells from allergic rhinitic and asthmatic pediatric patients

G. Santoni, C. Amantini, A. Bianchi, 2011, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

Candida albicans Expresses a Focal Adhesion Kinase-Like Protein That Undergoes Increased Tyrosine Phosphorylation upon Yeast Cell Adhesion to Vitronectin and the EA.hy 926 Human Endothelial Cell Line

G. Santoni, C. Amantini, J. Jacobelli, 2002, Infection and Immunity.

TRPV channels in tumor growth and progression.

G. Santoni, C. Amantini, Valerio Farfariello, 2011, Advances in experimental medicine and biology.

New Insight on the Role of Transient Receptor Potential (TRP) Channels in Driven Gliomagenesis Pathways

G. Santoni, C. Amantini, M. Santoni, 2011 .

The functional VNTR MNS16A of the TERT gene is associated with human longevity in a population of Central Italy

V. Napolioni, G. Santoni, G. Passarino, 2013, Experimental Gerontology.

Cannabigerol Induces Autophagic Cell Death by Inhibiting EGFR-RAS Pathways in Human Pancreatic Ductal Adenocarcinoma Cell Lines

G. Santoni, C. Amantini, M. Morelli, 2024, International journal of molecular sciences.

G. Santoni, C. Amantini, S. Cascinu, 2015, Oncoscience.

Anticancer effect of minor phytocannabinoids in preclinical models of multiple myeloma.

G. Santoni, C. Amantini, M. Morelli, 2024, BioFactors.