J. Morales

发表

DNA mismatch repair (MMR)‐dependent 5‐fluorouracil cytotoxicity and the potential for new therapeutic targets

M. Wagner, Longshan Li, J. Morales, 2009, British journal of pharmacology.

ATM-dependent IGF-1 induction regulates secretory clusterin expression after DNA damage and in genetic instability

B. Shankar, E. Goetz, L. Mayo, 2011, Oncogene.

Kub5-HeraRPRD1B Deficiency Promotes “BRCAness” and Vulnerability to PARP Inhibition in BRCA-proficient Breast Cancers

J. Minna, L. Girard, Yang Xie, 2018, Clinical Cancer Research.

The Kub5-Hera/RPRD1B interactome: a novel role in preserving genetic stability by regulating DNA mismatch repair

H. Garner, Yang Xie, Yunyun Zhou, 2016, Nucleic acids research.

The Kub5-Hera/RPRD1B interactome: a novel role in preserving genetic stability by regulating DNA mismatch repair

H. Garner, Yang Xie, Yunyun Zhou, 2016, Nucleic acids research.

XRN2 Is Required for Cell Motility and Invasion in Glioblastomas

J. Morales, M. Zalles, N. Smith, 2022, Cells.

XRN2 Links Transcription Termination to DNA Damage and Replication Stress

J. Manley, J. Morales, D. Boothman, 2016, PLoS genetics.

DNA Mismatch Repair-dependent Activation of c-Abl/p73α/GADD45α-mediated Apoptosis*

Longshan Li, J. Morales, D. Boothman, 2008, Journal of Biological Chemistry.

Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases.

Jinming Gao, Longshan Li, J. Morales, 2014, Critical reviews in eukaryotic gene expression.

RNA transcription termination factors and persistent R-loops: potential carcinogenic determinants after high or low LET IR.

M. Story, S. Burma, J. Morales, 2015 .

miR614 Expression Enhances Breast Cancer Cell Motility

J. Morales, G. Pearson, Tuyen T. Dang, 2020, International journal of molecular sciences.

Role of c-Abl Kinase in DNA Mismatch Repair-dependent G2 Cell Cycle Checkpoint Arrest Responses*

H. Garner, Longshan Li, J. Morales, 2008, Journal of Biological Chemistry.

Cellular Stress Responses to DNA Damage: An Intracellular Balance between Life, Senescence, and Death

E. Goetz, L. Mayo, M. Jackson, 2011 .

53BP1 Oligomerization is Independent of its Methylation by PRMT1

S. Elledge, L. Donehower, Bin Wang, 2005, Cell cycle.

Breaking in a new function for casein kinase 2.

J. Morales, P. Carpenter, 2004, Science of aging knowledge environment : SAGE KE.

Secretory clusterin (sCLU) is a hallmark sensor of DNA damage, cell stress, and cellular senescence: Evidence for similar regulation of sCLU expression after cellular stress and replicative senescence

B. Shankar, J. Morales, D. Boothman, 2007 .

Negative Cell Cycle Regulation and DNA Damage-inducible Phosphorylation of the BRCT Protein 53BP1*

J. Morales, W. Dunphy, P. Carpenter, 2001, The Journal of Biological Chemistry.

Involvement of POLA2 in Double Strand Break Repair and Genotoxic Stress

J. Morales, Tuyen T. Dang, 2020, International journal of molecular sciences.

Role for the BRCA1 C-terminal Repeats (BRCT) Protein 53BP1 in Maintaining Genomic Stability*

S. Elledge, W. Hittelman, J. Morales, 2003, The Journal of Biological Chemistry.

Loss of CENP-I Impairs Homologous Recombination and Sensitizes Cells to PARP1 Inhibition

J. Morales, Tuyen T. Dang, 2021, Cancers.

H2AX prevents DNA breaks from progressing to chromosome breaks and translocations.

Michael M. Murphy, F. Alt, S. Zha, 2006, Molecular cell.

DNA damage-induced G2–M checkpoint activation by histone H2AX and 53BP1

A. Nussenzweig, Junjie Chen, R. Camerini-Otero, 2002, Nature Cell Biology.

XRN2 interactome reveals its synthetic lethal relationship with PARP1 inhibition

J. Morales, Megha Khandelwal, F. Fattah, 2020, Scientific Reports.

Kub5-Hera, the human Rtt103 homolog, plays dual functional roles in transcription termination and DNA repair

Shwu‐Yuan Wu, C. Chiang, W. Hittelman, 2014, Nucleic acids research.

Award Number: W81XWH-12-1-0210 TITLE: Deconstruction of Oncogenic K-RAS Signaling Reveals Focal Adhesion Kinase as a Novel Therapeutic Target in NSCLC

J. Morales, D. Boothman, Niranjan Venkateswaran, 2016 .

Focal Adhesion Kinase Regulates the DNA Damage Response and Its Inhibition Radiosensitizes Mutant KRAS Lung Cancer

J. Morales, D. Boothman, P. Scaglioni, 2016, Clinical Cancer Research.

53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination

F. Alt, J. Kutok, J. Manis, 2004, Nature Immunology.

Tumor-selective, futile redox cycle-induced bystander effects elicited by NQO1 bioactivatable radiosensitizing drugs in triple-negative breast cancers.

Melissa C. Srougi, Wareef Kabbani, Longshan Li, 2014, Antioxidants & redox signaling.

53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis.

Michael M. Murphy, F. Alt, J. Manis, 2006, Proceedings of the National Academy of Sciences of the United States of America.

XRN2 Links RNA:DNA Hybrid Resolution to Double Strand Break Repair Pathway Choice

J. Morales, Tuyen T. Dang, 2020, Cancers.

[The role of CT scan in the diagnosis of renal cell carcinoma].

J. Morales, Yolanda Ares Valdés, Berardo V Amador Sandoval, 2004, Archivos españoles de urología.

Prognostic significance of the markers IDH1 and YKL40 related to the subventricular zone.

J. Morales, A. Kurbanov, A. Astudillo, 2015, Folia neuropathologica.