S. Greer

发表

DNA mismatch repair (MMR)‐dependent 5‐fluorouracil cytotoxicity and the potential for new therapeutic targets

M. Wagner, Longshan Li, J. Morales, 2009, British journal of pharmacology.

Studies on depurination of DNA by heat.

S. Greer, S. Zamenhof, 1962, Journal of molecular biology.

Inhibition of DNA methylation and reactivation of silenced genes by zebularine.

Wei Ye, Peter A. Jones, W. Ye, 2003, Journal of the National Cancer Institute.

Exploitation of elevated pyrimidine deaminating enzymes for selective chemotherapy.

S. Greer, D. Boothman, T. Briggle, 1989, Pharmacology & therapeutics.

Induced Gene Unstabilization

S. Greer, S. Zamenhof, R. D. Giovanni, 1958, Nature.

Potentiation of halogenated pyrimidine radiosensitizers in human carcinoma cells by beta-lapachone (3,4-dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran- 5,6-dione), a novel DNA repair inhibitor.

S. Greer, D. Boothman, A. Pardee, 1987, Cancer research.

Enzymatic basis for the selective inhibition of varicella-zoster virus by 5-halogenated analogues of deoxycytidine

S. Greer, M. Dobersen, M. Jerkofsky, 1976, Journal of virology.

Incorporation of 5-Substituted Analogs of Deoxycytidine into DNA of Herpes Simplex Virus-Infected or -Transformed Cells Without Deamination to the Thymidine Analog

S. Greer, M. Dobersen, L. Fox, 1983, Antimicrobial Agents and Chemotherapy.

Herpes simplex virus type 2 induced pyrimidine nucleoside kinase: enzymatic basis for the selective antiherpetic effect of 5-halogenated analogues of deoxycytidine.

S. Greer, M. Dobersen, 1978, Biochemistry.

Protective, tumor-selective dual pathway activation of 5-fluoro-2'-deoxycytidine provided by tetrahydrouridine in mice bearing mammary adenocarcinoma-755.

S. Greer, D. Boothman, T. Briggle, 1987, Cancer research.

Use of 5-trifluoromethyldeoxycytidine and tetrahydrouridine to circumvent catabolism and exploit high levels of cytidine deaminase in tumors to achieve DNA- and target-directed therapies.

S. Greer, D. Boothman, J. Mekras, 1985, Cancer research.

Role of catabolism in pyrimidine utilization for nucleic acid synthesis in vivo.

G. Cooper, S. Greer, W. F. Dunning, 1972, Cancer research.

5‐HALOGENATED ANALOGS OF DEOXYCYTIDINE AS SELECTIVE INHIBITORS OF THE REPLICATION OF HERPES SIMPLEX VIRUSES IN CELL CULTURE AND RELATED STUDIES OF INTRACRANIAL HERPES SIMPLEX VIRUS INFECTIONS IN MICE *

S. Greer, I. Schildkraut, T. Zimmerman, 1975, Annals of the New York Academy of Sciences.

DIFFERENTIAL STABILITIES OF INDIVIDUAL HEREDITY DETERMINANTS IN TRANSFORMING PRINCIPLE

S. Greer, S. Zamenhof, G. Leidy, 1957, Journal of bacteriology.

Host-cell reactivation of UV-irradiated and chemically-treated herpes simplex virus-1 by xeroderma pigmentosum, XP heterozygotes and normal skin fibroblasts.

S. Greer, C. Selsky, 1978, Mutation research.

Methylation of HSV-1 DNA as a mechanism of viral inhibition: studies of an analogue of methyldeoxycytidine: trifluoromethyldeoxycytidine (F3mdCyd).

S. Greer, J. Barletta, 1992, Antiviral research.

Selective inhibition of the replication of herpes simplex virus by 5-halogenated analogues of deoxycytidine.

G. Cooper, S. Greer, I. Schildkraut, 1975, Molecular pharmacology.

The effect of inhibition of cytidine deaminase by tetrahydrouridine on the utilization of deoxycytidine and 5-bromodeoxycytidine for deoxyribonucleic acid synthesis.

G. Cooper, S. Greer, 1973, Molecular pharmacology.

Capacity of deoxycytidine to selectively antagonize cytotoxicity of 5-halogenated analogs of deoxycytidine without loss of antiherpetic activity

C. B. Bagwell, S. Greer, L. Fox, 1982, Antimicrobial Agents and Chemotherapy.

Analysis of 5-fluoro-2'-deoxycytidine and 5-trifluoromethyl-2'-deoxycytidine and their related antimetabolites by high-performance liquid chromatography.

S. Greer, D. Boothman, C. Pfaffenberger, 1986, Journal of chromatography.

Phosphorylation of 5-halogenated deoxycytidine analogues by deoxycytidine kinase.

G. Cooper, S. Greer, 1973, Molecular pharmacology.

SELECTIVE INHIBITION OF THE REPLICATION OF VARICELLA‐ZOSTER VIRUS BY 5‐HALOGENATED ANALOGS OF DEOXYCYTIDINE *

S. Greer, M. Dobersen, M. Jerkofsky, 1977, Annals of the New York Academy of Sciences.

Radiation, pool size and incorporation studies in mice with 5-chloro-2'-deoxycytidine.

S. Greer, D. Boothman, T. Briggle, 1990, International journal of radiation oncology, biology, physics.

Use of 5-fluorodeoxycytidine and tetrahydrouridine to exploit high levels of deoxycytidylate deaminase in tumors to achieve DNA- and target-directed therapies.

S. Greer, D. Boothman, J. Mekras, 1984, Cancer research.

Five-chlorodeoxycytidine, a tumor-selective enzyme-driven radiosensitizer, effectively controls five advanced human tumors in nude mice.

S. Greer, A. Knapinska, M. Dauphinée, 2001, International journal of radiation oncology, biology, physics.

Mice Bearing Mammary Adenocarcinoma-755-deoxycytidine Provided by Tetrahydrouridine in ′ 5-Fluoro-2 Protective , Tumor-selective Dual Pathway Activation of Updated Version

S. Greer, D. Boothman, T. Briggle, 2006 .

Sensitization to X ray by 5-chloro-2'-deoxycytidine co-administered with tetrahydrouridine in several mammalian cell lines and studies of 2'-chloro derivatives.

S. Greer, L. M. Perez, 1986, International journal of radiation oncology, biology, physics.

Marked radiosensitization of cells in culture to X ray by 5-chlorodeoxycytidine coadministered with tetrahydrouridine, and inhibitors of pyrimidine biosynthesis.

S. Greer, T. Briggle, J. Mekras, 1984, International journal of radiation oncology, biology, physics.

Preferential response of cancer cells to zebularine.

Gangning Liang, Peter A. Jones, D. Weisenberger, 2004, Cancer cell.

Five-chlorodeoxycytidine and biomodulators of its metabolism result in fifty to eighty percent cures of advanced EMT-6 tumors when used with fractionated radiation.

J. Schwade, S. Greer, H. Marion, 1995, International journal of radiation oncology, biology, physics.

5-chlorodeoxycytidine, a radiosensitizer effective against RIF-1 and Lewis lung carcinoma, is also effective against a DMBA-induced mammary adenocarcinoma and the EMT-6 tumor in BALB/c mice.

J. Schwade, S. Greer, C. Gottlieb, 1992, International journal of radiation oncology, biology, physics.

5-Fluorouracil in Mice Bearing Lewis Lung Carcinoma Coadministered with Tetrahydrouridine Compared to-deoxycytidine ′ Tumor-selective Metabolism of 5-Fluoro-2 Updated Version

S. Greer, D. Boothman, T. Briggle, 2006 .

Tumor-selective metabolism of 5-fluoro-2'-deoxycytidine coadministered with tetrahydrouridine compared to 5-fluorouracil in mice bearing Lewis lung carcinoma.

S. Greer, D. Boothman, T. Briggle, 1987, Cancer research.

An assay for pyrimidine deoxyribonucleoside kinase using γ-32P-labeled ATP

S. Greer, M. Dobersen, 1975 .

Metabolic channeling of 5-fluoro-2'-deoxycytidine utilizing inhibitors of its deamination in cell culture.

S. Greer, D. Boothman, T. Briggle, 1985, Molecular pharmacology.

An assay for pyrimidine deoxyribonucleoside kinase using gamma-32P-labeled ATP.

S. Greer, M. Dobersen, 1975, Analytical biochemistry.

Heat as an Agent producing High Frequency of Mutations and Unstable Genes in Escherichia coli

S. Greer, S. Zamenhof, 1958, Nature.

Use of 5-fluorodeoxycytidine and tetrahydrouridine to exploit high levels of deoxycytidylate deaminase in tumors: Target directed conversion of a nontoxic analog to a toxic antimetabolite

S. Greer, J. Mekras, 1983 .

Suppression by Derepression in Threonine Dehydratase-Deficient Mutants of Bacillus subtilis

S. Greer, D. Vapnek, 1971, Journal of bacteriology.

Suppression byDerepression inThreonine Dehydratase-Deficient MutantsofBacillus subtilis

S. Greer, D. Vapnek, 1971 .

Viruses of Cariogenic Streptococci

S. Greer, G. Musil, D. D. Zinner, 1971, Journal of dental research.

STUDY OF SPONTANEOUS GENE UNSTABILIZATION IN ESCHERICHIA COLI

S. Greer, R. De Giovanni, S. Zamenhof, 1958, Journal of bacteriology.

Inhibition of the replication of human cytomegalovirus by bromodeoxycytidine in the absence of detectable increases in bromodeoxycytidine kinase activity.

S. Greer, M. Dobersen, M. Jerkofsky, 1980, Intervirology.

Minor Threonine Dehydratase Encoded Within the Threonine Synthetic Region of Bacillus subtilis

S. Greer, D. Vapnek, 1971, Journal of bacteriology.

Threonine synthetase of Bacillus subtilis. The nature of an associated dehydratase activity.

S. Greer, M. Skarstedt, 1973, The Journal of biological chemistry.

Threonine Synthetase-Catalyzed Conversion of Phosphohomoserine to α-Ketobutyrate in Bacillus subtilis

S. Greer, I. Schildkraut, Sheldon Greer, 1973, Journal of bacteriology.