J. Modiano

J. Modiano, E. McNiel, B. Husbands, 2010, Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association.

S100A4 mRNA-protein relationship uncovered by measurement noise reduction

Iain G. Johnston, I. Johnston, T. Nussbaumer, 2020, Journal of Molecular Medicine.

Association of Sphingosine‐1‐phosphate (S1P)/S1P Receptor‐1 Pathway with Cell Proliferation and Survival in Canine Hemangiosarcoma

I. Cohen, J. Modiano, I. Cohen, 2015, Journal of veterinary internal medicine.

Association of Sphingosine‐1‐phosphate (S1P)/S1P Receptor‐1 Pathway with Cell Proliferation and Survival in Canine Hemangiosarcoma

I. Cohen, J. Modiano, J. Kim, 2015, Journal of veterinary internal medicine.

Growth arrest of melanoma cells is differentially regulated by contact inhibition and serum deprivation.

J. Modiano, R. Smith, J. Wojcieszyn, 1999, DNA and cell biology.

The molecular basis of canine melanoma: pathogenesis and trends in diagnosis and therapy.

J. Modiano, J. Wojcieszyn, M. Ritt, 1999, Journal of veterinary internal medicine.

Expression and Significance of p53, Rb, p21/waf-1, p16/ink-4a, and PTEN Tumor Suppressors in Canine Melanoma

S. Fosmire, J. Modiano, A. Koenig, 2002, Veterinary pathology.

Sustained nuclear localization of p21/WAF-1 upon growth arrest induced by contact inhibition.

J. Modiano, R. Smith, J. Wojcieszyn, 2000, Cancer letters.

Functional Loss of p21/Waf-1 in a Case of Benign Canine Multicentric Melanoma

J. Modiano, J. Wojcieszyn, M. Ritt, 1998, Veterinary pathology.

Comparative analysis of genome-wide DNA methylation identifies patterns that associate with conserved transcriptional programs in osteosarcoma

T. Richmond, K. Beckman, Subbaya Subramanian, 2020, bioRxiv.

Binding of VEGF-A to canine cancer cells with preferential expression of VEGFR1.

J. Modiano, A. Borgatti, M. Duckett, 2014 .

Molecular characterization of canine BCR-ABL-positive chronic myelomonocytic leukemia before and after chemotherapy.

J. Modiano, D. Ito, M. Breen, 2013, Veterinary clinical pathology.

Impact of Repeated Cycles of EGF Bispecific Angiotoxin (eBAT) Administered at a Reduced Interval from Doxorubicin Chemotherapy in Dogs with Splenic Hemangiosarcoma.

J. Koopmeiners, J. Modiano, D. Vallera, 2020, Veterinary and comparative oncology.

Targeted sequencing of candidate gene regions for myelofibrosis in dogs

J. Modiano, D. Seelig, K. Minor, 2022, Journal of veterinary internal medicine.

Radiotherapy enhances natural killer cell cytotoxicity and localization in pre-clinical canine sarcomas and first-in-dog clinical trial

J. Modiano, Jesus I. Luna, W. Murphy, 2017, Journal of Immunotherapy for Cancer.

CD40 ligand is necessary and sufficient to support primary diffuse large B-cell lymphoma cells in culture: a tool for in vitro preclinical studies with primary B-cell malignancies

J. Modiano, D. Ito, M. Breen, 2012, Leukemia & lymphoma.

Gene Expression Profiles of Sporadic Canine Hemangiosarcoma Are Uniquely Associated with Breed

T. Phang, L. Hunter, J. Modiano, 2009, PloS one.

Enhancing antimelanoma immune responses through apoptosis

G. Cutter, S. Fosmire, J. Modiano, 2003, Cancer Gene Therapy.

Nfatc2 and Tob1 Have Non-Overlapping Function in T Cell Negative Regulation and Tumorigenesis

J. Modiano, D. Bellgrau, M. G. O’Sullivan, 2014, PloS one.

Establishment of a Patient-Derived Xenograft of Canine Enteropathy-Associated T-Cell Lymphoma, Large Cell Type.

J. Modiano, M. G. O’Sullivan, D. Seelig, 2017, Journal of comparative pathology.

Anti-Insulin Immune Responses Are Detectable in Dogs with Spontaneous Diabetes

W. Robinson, L. Steinman, J. Modiano, 2016, PloS one.

Mutations of Phosphatase and Tensin Homolog Deleted from Chromosome 10 in Canine Hemangiosarcoma

S. Fosmire, J. Modiano, E. Dickerson, 2005, Veterinary pathology.

Biomonitoring the cooked meat carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in canine fur.

J. Modiano, R. Turesky, Dan Gu, 2012, Journal of agricultural and food chemistry.

Protein kinase C regulates both production and secretion of interleukin 2.

P. Nowell, J. Modiano, R. Lamb, 1991, The Journal of biological chemistry.

G. Cutter, J. Modiano, D. Ito, 2011, Journal of veterinary internal medicine.

Evaluation of coated platelets, a subset of highly procoagulant platelets, in healthy dogs and dogs with neoplasia.

Ashley J. Schulte, J. Modiano, A. Rendahl, 2022, American journal of veterinary research.

Nicotine Activates Nuclear Factor of Activated T Cells c2 (NFATc2) and Prevents Cell Cycle Entry in T Cells

S. Baksh, S. Fosmire, J. Modiano, 2004, Journal of Pharmacology and Experimental Therapeutics.

Induction of lymphokine-activated killer (LAK) activity in canine lymphocytes with low dose human recombinant interleukin-2 in vitro.

J. Modiano, J. Hank, P. Sondel, 1994, Cancer biotherapy.

Diagnosis of Canine Lymphoid Neoplasia Using Clonal Rearrangements of Antigen Receptor Genes

J. Modiano, P. Moore, A. Avery, 2003, Veterinary pathology.

Alignment of collagen matrices using magnetic nanowires and magnetic barcode readout using first order reversal curves (FORC) (invited)

J. Modiano, Anirudh Sharma, A. Hubel, 2017, Journal of Magnetism and Magnetic Materials.

Functional interleukin-2 receptors are expressed on natural killer-like leukemic cells from a dog with cutaneous lymphoma.

E. Gelfand, J. Modiano, P. Moore, 1995, Blood.

Potential to Target Dysregulated Interleukin-2 Receptor Expression in Canine Lymphoid and Hematopoietic Malignancies as a Model for Human Cancer

S. Fosmire, J. Modiano, E. Dickerson, 2002, Journal of immunotherapy.

Abbreviations ALT : Alanine aminotransferase AST : Aspartate transaminase BUN : Blood urea nitrogen CPK : Creatine phosphokinase CR : Complete response DLT : Dose limiting toxicity FOSCC : Feline oral squamous cell carcinoma

J. Modiano, M. G. O’Sullivan, G. Unger, 2017 .

Immunotherapy with autologous tumour antigen-coated microbeads (large multivalent immunogen), IL-2 and GM-CSF in dogs with spontaneous B-cell lymphoma.

J. Modiano, J. Miller, J. Curtsinger, 2011, Veterinary and comparative oncology.

Predictive value of p16 or Rb inactivation in a model of naturally occurring canine non-Hodgkin's lymphoma

G. Cutter, J. Modiano, V. Valli, 2007, Leukemia.

A Bayesian adaptive Phase I–II clinical trial for evaluating efficacy and toxicity with delayed outcomes

J. Koopmeiners, J. Modiano, 2014, Clinical trials.

Extending the TITE CRM to Multiple Outcomes with Application to a Phase 1 Clinical Trial in Canine Hemangiosarcoma

J. Koopmeiners, J. Modiano, 2012 .

Evolutionarily conserved resistance to phagocytosis observed in melanoma cells is insensitive to upregulation of pro-phagocytic signals and to CD47 blockade

I. Weissman, J. Modiano, D. Ito, 2019, Melanoma research.

Results of a Phase I Dose Escalation Study of the Novel, Oral CRM1 Selective Inhibitor of Nuclear Export (SINE) KPT-335 in Dogs with Spontaneous Non-Hodgkin's Lymphomas (NHL)

J. Modiano, D. Ito, W. Kisseberth, 2012 .

Development of a Biolabeling System Using Ferromagnetic Nanowires

Rhonda R. Franklin, J. Modiano, Z. Nemati, 2019, IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology.

Fas ligand-dependent suppression of autoimmunity via recruitment and subsequent termination of activated T cells.

J. Modiano, D. Bellgrau, R. Gianani, 2004, Clinical immunology.

Molecular Cancer Attenuation of Pten Increases P21 Stability and Cytosolic Localization in Kidney Cancer Cells: a Potential Mechanism of Apoptosis Resistance

S. Baksh, Pei-yin Lin, S. Fosmire, 2022 .

Ectodomain shedding by ADAM17 (a disintegrin and metalloproteinase 17) in canine neutrophils.

J. Modiano, K. Snyder, B. Walcheck, 2020, Veterinary immunology and immunopathology.

Ectodomain shedding of L-selectin by ADAM17 in canine neutrophils

J. Modiano, K. Snyder, B. Walcheck, 2020, bioRxiv.

Abstract 3809: Evaluation of the novel, orally bioavailable selective inhibitor of nuclear export (SINE) KPT-335 (verdinexor) in spontaneous canine cancer: Results of phase I and phase II clinical trials

M. Pennell, J. Modiano, D. Ito, 2014 .

Inactivation of the p16 Cyclin-Dependent Kinase Inhibitor in High-Grade Canine Non-Hodgkin's T-Cell Lymphoma

G. Cutter, S. Fosmire, J. Modiano, 2007, Veterinary pathology.

Bone marrow cytological findings in 4 dogs and a cat with hemophagocytic syndrome.

J. Modiano, S. Wheeler, M. Thrall, 1996, Journal of veterinary internal medicine.

Expression of S100a, Vimentin, NSE, and Melan A/MART-1 in Seven Canine Melanoma Cell Lines and Twenty-nine Retrospective Cases of Canine Melanoma

J. Modiano, B. Weeks, A. Koenig, 2001, Veterinary pathology.

Artemisinin Blocks Prostate Cancer Growth and Cell Cycle Progression by Disrupting Sp1 Interactions with the Cyclin-dependent Kinase-4 (CDK4) Promoter and Inhibiting CDK4 Gene Expression*

G. Firestone, J. Modiano, J. Willoughby, 2009, Journal of Biological Chemistry.

Gene expression profiling identifies inflammation and angiogenesis as distinguishing features of canine hemangiosarcoma

G. Cutter, T. Phang, L. Hunter, 2010, BMC Cancer.

Canine malignant hemangiosarcoma as a model of primitive angiogenic endothelium

S. Fosmire, J. Modiano, E. Dickerson, 2004, Laboratory Investigation.

Identification of three molecular and functional subtypes in canine hemangiosarcoma through gene expression profiling and progenitor cell characterization.

K. Lindblad-Toh, J. Modiano, A. Sarver, 2014, The American journal of pathology.

Canine lymphoma as a comparative model for human non-Hodgkin lymphoma: recent progress and applications.

J. Modiano, D. Ito, A. Frantz, 2014, Veterinary immunology and immunopathology.

Distinct B-cell and T-cell lymphoproliferative disease prevalence among dog breeds indicates heritable risk.

Paul R. Avery, K. Lindblad-Toh, E. Ostrander, 2005, Cancer research.

CD20 Expression in Normal Canine B Cells and in Canine non-Hodgkin Lymphoma

S. Fosmire, J. Modiano, D. Bellgrau, 2005, Veterinary pathology.

Molecular Profiling Reveals Prognostically Significant Subtypes of Canine Lymphoma

K. Lindblad-Toh, T. Phang, L. Hunter, 2013, Veterinary pathology.

Shared pathogenesis of human and canine tumors - an inextricable link between cancer and evolution

J. Modiano, M. Breen, 2008 .

Progesterone augments proliferation induced by epidermal growth factor in a feline mammary adenocarcinoma cell line

P. Nowell, C. Lyttle, D. Weiner, 1991, Journal of cellular biochemistry.

Targeting of Beta Adrenergic Receptors Results in Therapeutic Efficacy against Models of Hemangioendothelioma and Angiosarcoma

Laura E. Boucheron, Victor Kokta, L. Boucheron, 2013, PloS one.

Progress in Adaptive Immunotherapy for Cancer in Companion Animals: Success on the Path to a Cure

J. Modiano, K. L. Anderson, 2015, Veterinary sciences.

Evolutionarily conserved cytogenetic changes in hematological malignancies of dogs and humans – man and his best friend share more than companionship

J. Modiano, M. Breen, 2008, Chromosome Research.

Bispecific Targeting of EGFR and Urokinase Receptor (uPAR) Using Ligand-Targeted Toxins in Solid Tumors

J. Modiano, V. Bachanova, D. Vallera, 2020, Biomolecules.

Eradication of Canine Diffuse Large B-Cell Lymphoma in a Murine Xenograft Model with CD47 Blockade and Anti-CD20

I. Weissman, A. Barkal, J. Modiano, 2016, Cancer Immunology Research.

Isolation and characterization of canine natural killer cells.

J. Modiano, D. Ito, Bin Zhang, 2013, Veterinary immunology and immunopathology.

Characterization and Potential Applications of Dog Natural Killer Cells in Cancer Immunotherapy

J. Modiano, R. Canter, Alicia A. Gingrich, 2019, Journal of clinical medicine.

Blood and tissue biomarker analysis in dogs with osteosarcoma treated with palliative radiation and intra-tumoral autologous natural killer cell transfer

J. Modiano, R. Rebhun, W. Murphy, 2019, bioRxiv.

Canine cancer immunotherapy studies: linking mouse and human

J. Modiano, R. Rebhun, Jesus I. Luna, 2016, Journal of Immunotherapy for Cancer.

Posttranscriptional regulation of T-cell IL-2 production by human pooled immunoglobin.

E. Gelfand, J. Modiano, G. Lack, 1997, Clinical immunology and immunopathology.

Use of the Cell-Dyn 3500 to predict leukemic cell lineage in peripheral blood of dogs and cats.

J. Modiano, A. Avery, Roger D. Smith, 2002, Veterinary clinical pathology.

Risk Factors for Development of Canine and Human Osteosarcoma: A Comparative Review

J. Modiano, A. Sarver, L. Spector, 2019, Veterinary sciences.

Perturbation of 14q32 miRNAs-cMYC gene network in osteosarcoma.

V. Thayanithy, Subbaya Subramanian, C. Steer, 2012, Bone.

Hydroquinone and catechol interfere with T cell cycle entry and progression through the G1 phase.

J. Modiano, J. McCue, S. Lazis, 2003, Molecular immunology.

Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions

Ashley J. Schulte, K. Lindblad-Toh, E. Karlsson, 2021, Molecular Cancer Research.

Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene Fusions

Ashley J. Schulte, K. Lindblad-Toh, E. Karlsson, 2020, Molecular Cancer Research.

Influence of genetic background on tumor karyotypes: Evidence for breed-associated cytogenetic aberrations in canine appendicular osteosarcoma

P. Tsai, C. Langford, G. Cutter, 2009, Chromosome Research.

A comparison of risk factors for metastasis at diagnosis in humans and dogs with osteosarcoma

D. Largaespada, J. Modiano, L. Spector, 2019, Cancer medicine.

Generation of Suppressive Monocytes Extracellular Vesicles Secreted by Tumor Cells Promote the

J. Modiano, J. Olson, J. Lenz, 2021 .

Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background

E. Mauceli, K. Lindblad-Toh, G. Getz, 2015, Genome research.

Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach.

K. Lindblad-Toh, G. Cutter, L. Hunter, 2011, Bone.

Inflammation, Apoptosis, and Necrosis Induced by Neoadjuvant Fas Ligand Gene Therapy Improves Survival of Dogs With Spontaneous Bone Cancer.

G. Cutter, V. Wilke, J. Modiano, 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

Heterotypic mouse models of canine osteosarcoma recapitulate tumor heterogeneity and biological behavior

Subbaya Subramanian, J. Modiano, B. Bryan, 2016, Disease Models & Mechanisms.

MicroRNAs at the human 14q32 locus have prognostic significance in osteosarcoma

A. Cleton-Jansen, V. Thayanithy, Subbaya Subramanian, 2013, Orphanet Journal of Rare Diseases.

Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma , including regulatory variants near CDKN 2 A / B

K. Lindblad-Toh, E. Lander, C. Howald, 2013 .

Naturally occurring translational models for development of cancer gene therapy

S. Fosmire, J. Modiano, D. Bellgrau, 2006 .

Safe and Effective Sarcoma Therapy through Bispecific Targeting of EGFR and uPAR

K. Lindblad-Toh, J. Koopmeiners, Jonathan C. Henriksen, 2017, Molecular Cancer Therapeutics.

Combinatorial Treatment of DNA and Chromatin-Modifying Drugs Cause Cell Death in Human and Canine Osteosarcoma Cell Lines

V. Thayanithy, Subbaya Subramanian, C. Steer, 2012, PloS one.

Transcriptional and Functional Activity of Canine Hemangiosarcoma to Support

Ashley J. Schulte, K. Lindblad-Toh, M. Meyerson, 2021 .

Comparative analysis of genome-wide DNA methylation identifies patterns that associate with conserved transcriptional programs in osteosarcoma.

T. Richmond, K. Beckman, Subbaya Subramanian, 2020, Bone.

Aberrant Retinoblastoma (RB)-E2F Transcriptional Regulation Defines Molecular Phenotypes of Osteosarcoma*

Jyotika Varshney, Aaron L. Sarver, J. V. Van Etten, 2015, The Journal of Biological Chemistry.

A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis

Natalie K. Wolf, Madison T. Weg, D. Largaespada, 2015, Nature Genetics.

Retrovirus-like activity in an immunosuppressed dog: pathological and immunological findings.

J. Modiano, T. V. Van Winkle, G. Cockerell, 1995, Journal of comparative pathology.

Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma

Daniel M. Rotroff, K. Lindblad-Toh, A. Motsinger-Reif, 2014, Chromosome Research.

Anti-Cancer Activity of PAK4/NAMPT Inhibitor and Programmed Cell Death Protein-1 Antibody in Kidney Cancer.

E. Baloglu, K. Jen, J. Modiano, 2020, Kidney360.

J. Koopmeiners, Bartek Rajwa, J. Modiano, 2017, F1000Research.

Comparative Approach to the Temporo-Spatial Organization of the Tumor Microenvironment

M. Dewhirst, J. Modiano, A. Sarver, 2019, Front. Oncol..

Increased risk of cancer in dogs and humans: A consequence of recent extension of lifespan beyond evolutionarily determined limitations?

Ashley J. Schulte, J. Modiano, A. Sarver, 2022, Aging and cancer.

Constitutive activation of alternative nuclear factor kappa B pathway in canine diffuse large B-cell lymphoma contributes to tumor cell survival and is a target of new adjuvant therapies

K. Lindblad-Toh, J. Modiano, D. Ito, 2017, Leukemia & lymphoma.

Refining tumor-associated aneuploidy through ‘genomic recoding’ of recurrent DNA copy number aberrations in 150 canine non-Hodgkin lymphomas

K. Lindblad-Toh, A. Motsinger-Reif, E. Seiser, 2011, Leukemia & lymphoma.

22 Breed-specific Canine Lymphoproliferative Diseases

J. Modiano, M. Breen, C. London, 2006 .

Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors.

Francis Galibert, Kerstin Lindblad-Toh, Matthew Breen, 2005, Genome research.

Genome-wide Association Study Identifies Shared Risk Loci Common to Two Malignancies in Golden Retrievers

E. Mauceli, K. Lindblad-Toh, E. Lander, 2015, PLoS genetics.

NFATc2-mediated repression of cyclin-dependent kinase 4 expression.

J. Decaprio, D. Fisher, S. Baksh, 2002, Molecular cell.

Development of a novel anti-canine CD20 monoclonal antibody with diagnostic and therapeutic potential

J. Modiano, D. Ito, M. Beall, 2015, Leukemia & lymphoma.

Preclinical Evaluation of the Novel, Orally Bioavailable Selective Inhibitor of Nuclear Export (SINE) KPT-335 in Spontaneous Canine Cancer: Results of a Phase I Study

M. Pennell, J. Modiano, D. Ito, 2014, PloS one.

MiR-9 is overexpressed in spontaneous canine osteosarcoma and promotes a metastatic phenotype including invasion and migration in osteoblasts and osteosarcoma cell lines

J. Modiano, M. Bear, W. Kisseberth, 2016, BMC Cancer.

Comparative Genomics Reveals Shared Mutational Landscape in Canine Hemangiosarcoma and Human Angiosarcoma

Ashley J. Schulte, K. Lindblad-Toh, E. Karlsson, 2019, Molecular Cancer Research.

Genomic analysis reveals shared genes and pathways in human and canine angiosarcoma

K. Lindblad-Toh, E. Karlsson, Jason Turner-Maier, 2019, bioRxiv.

Interactions between CXCR4 and CXCL12 promote cell migration and invasion of canine hemangiosarcoma

K. Lindblad-Toh, J. Modiano, M. Breen, 2017, Veterinary and comparative oncology.

WHAT’S NEW IN CANCER DIAGNOSIS AND THERAPY

J. Modiano, 2014 .

Modulation of fatty acid metabolism and immune suppression are features of in vitro tumour sphere formation in ontogenetically distinct dog cancers

J. Modiano, E. Dickerson, T. O’Brien, 2018, Veterinary and comparative oncology.

Correction: Genome-wide Association Study Identifies Shared Risk Loci Common to Two Malignancies in Golden Retrievers

E. Mauceli, K. Lindblad-Toh, E. Lander, 2015, PLoS genetics.

Genome-wide Association Study Identifies Shared Risk Loci Common to Two Malignancies in Golden Retrievers Citation Tonomura

E. Mauceli, K. Lindblad-Toh, E. Lander, 2015 .

Interleukin-8 promotes canine hemangiosarcoma growth by regulating the tumor microenvironment.

J. Modiano, E. Dickerson, T. O’Brien, 2014, Experimental cell research.

Hemangiosarcoma and its cancer stem cell subpopulation are effectively killed by a toxin targeted through epidermal growth factor and urokinase receptors

J. Modiano, E. Dickerson, D. Vallera, 2013, International journal of cancer.

Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma

K. Lindblad-Toh, A. Motsinger-Reif, D. Rotroff, 2014, Chromosome Research.

Applicability of 3T body MRI in assessment of nonfocal bone marrow involvement of hematopoietic neoplasia in dogs.

J. Modiano, D. Feeney, T. O’Brien, 2013, Journal of veterinary internal medicine.

Polymorphisms within the Telomerase Reverse Transcriptase gene (TERT) in four breeds of dogs selected for difference in lifespan and cancer susceptibility

K. Silverstein, J. Modiano, A. Bagchi, 2014, BMC Veterinary Research.

Sensitivity of osteosarcoma cells to HDAC inhibitor AR-42 mediated apoptosis

S. Kulp, J. Modiano, W. Kisseberth, 2017, BMC Cancer.

Negative regulators in homeostasis of naïve peripheral T cells

J. Modiano, D. Bellgrau, L. D. Johnson, 2008, Immunologic research.

Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma.

Natalie K. Wolf, D. Largaespada, R. LaRue, 2018, Cancer research.

Quantitative and qualitative signals determine T-cell cycle entry and progression.

E. Gelfand, J. Modiano, N. Sakata, 1999, Cellular immunology.

The use of cytochemistry, immunophenotyping, flow cytometry, and in vitro differentiation to determine the ontogeny of a canine monoblastic leukemia.

J. Modiano, C. Ball, R. Smith, 1998, Veterinary clinical pathology.

Stimulation with Concanavalin-A Induces IL-17 Production by Canine Peripheral T Cells

J. Modiano, T. O’Brien, M. Ritt, 2015, Veterinary sciences.

Nicotine-mediated signals modulate cell death and survival of T lymphocytes.

S. Baksh, S. Fosmire, J. Modiano, 2010, Toxicology and applied pharmacology.

Chronic Nicotine Consumption Does Not Influence 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone–Induced Lung Tumorigenesis

J. Modiano, S. Murphy, F. Kassie, 2011, Cancer Prevention Research.

Deciphering the molecular landscape and the tumor microenvironment of perivascular epitheloid cell neoplasma (PEComa).

J. Modiano, A. Schwabegger, W. Korn, 2021 .

FAS ligand gene transfer for cancer therapy

J. Modiano, D. Bellgrau, J. Schaack, 2005 .

Mammary mass aspirate from a Yorkshire terrier.

J. Modiano, Peter J. Fernandes, C. Guyer, 1998, Veterinary clinical pathology.

Regulation of synthesis and activity of the PLSTIRE protein (cyclin-dependent kinase 6 (cdk6)), a major cyclin D-associated cdk4 homologue in normal human T lymphocytes.

E. Gelfand, J. Modiano, J. Lucas, 1995, Journal of immunology.

Fas ligand based immunotherapy: A potent and effective neoadjuvant with checkpoint inhibitor properties, or a systemically toxic promoter of tumor growth?

J. Modiano, D. Bellgrau, 2016, Discovery medicine.

Therapeutic Targeting of Protein Kinase CK2 Gene Expression in Feline Oral Squamous Cell Carcinoma: A Naturally Occurring Large-Animal Model of Head and Neck Cancer.

J. Modiano, M. G. O’Sullivan, G. Unger, 2017, Human gene therapy. Clinical development.

MHC-dependent desensitization of intrinsic anti-self reactivity

G. Cutter, M. Baier, J. Modiano, 2009, Cancer Immunology, Immunotherapy.

Distinct mechanisms of PTEN inactivation in dogs and humans highlight convergent molecular events that drive cell division in the pathogenesis of osteosarcoma.

Subbaya Subramanian, J. Modiano, A. Sarver, 2023, Cancer genetics.

Retrospective evaluation of thrombocytopenia and tumor stage as prognostic indicators in dogs with splenic hemangiosarcoma.

J. Modiano, A. Rendahl, A. Borgatti, 2021, Journal of the American Veterinary Medical Association.

Bioapplications of Magnetic Nanowires: Barcodes, Biocomposites, Heaters

P. Visscher, J. Modiano, R. Franklin, 2022, IEEE Transactions on Magnetics.

Enrichment and Quantification of Epitope-specific CD4+ T Lymphocytes using Ferromagnetic Iron-gold and Nickel Nanowires

J. Modiano, M. Jenkins, B. Stadler, 2018, Scientific Reports.

MiR-9 is overexpressed in spontaneous canine osteosarcoma and promotes a metastatic phenotype including invasion and migration in osteoblasts and osteosarcoma cell lines

J. Modiano, M. Bear, W. Kisseberth, 2016, BMC Cancer.

Mesenchymal stromal cells inhibit murine syngeneic anti-tumor immune responses by attenuating inflammation and reorganizing the tumor microenvironment

J. Tolar, J. Modiano, C. Forster, 2015, Cancer Immunology, Immunotherapy.

Extracellular Vesicles Secreted by Tumor Cells Promote the Generation of Suppressive Monocytes

J. Modiano, J. Olson, J. Lenz, 2021, ImmunoHorizons.

Development of an exosomal gene signature to detect residual disease in dogs with osteosarcoma using a novel xenograft platform and machine learning

G. Cutter, Subbaya Subramanian, J. Modiano, 2021, bioRxiv.

Abstract 5357: Mutational and transcriptomic profiling identify distinct angiogenic and inflammatory subtypes of angiosarcoma

K. Lindblad-Toh, E. Karlsson, J. Modiano, 2018, Molecular and Cellular Biology / Genetics.

Oncolytic vesicular stomatitis virus is safe and provides a survival benefit for dogs with naturally occurring osteosarcoma

M. Farrar, J. Koopmeiners, J. Modiano, 2023, bioRxiv.

Comparative Pathogenesis of Cancers in Animals and Humans

J. Modiano, 2016, Veterinary sciences.

Stage-specific embryonic antigen: determining expression in canine glioblastoma, melanoma, and mammary cancer cells

J. Modiano, D. Ito, Weiming Lin, 2017, Journal of veterinary science.

Lymphadenopathy in dogs

J. Modiano, C. Cannon, M. Ritt, 2017 .

Isolation and characterization of canine natural killer cells.

J. Modiano, D. Ito, Bin Zhang, 2013, Veterinary immunology and immunopathology.

Neoadjuvant systemic oncolytic vesicular stomatitis virus is safe and may enhance long-term survivorship in dogs with naturally occurring osteosarcoma

J. Koopmeiners, J. Modiano, A. Sarver, 2023, bioRxiv.

Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma.

Natalie K. Wolf, D. Largaespada, R. LaRue, 2018, Cancer research.

Identification of three molecular and functional subtypes in canine hemangiosarcoma through gene expression profiling and progenitor cell characterization.

K. Lindblad-Toh, J. Modiano, A. Sarver, 2014, American Journal of Pathology.