Y. Tong

发表

Synthesis and in-vitro biological activity of macrocyclic urea Chk1 inhibitors.

Philip J. Merta, Gaoquan Li, Z. Tao, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of 4'-(6,7-disubstituted-2,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-biphenyl-4-ol as potent Chk1 inhibitors.

Saul H Rosenberg, Philip J. Merta, Gaoquan Li, 2007, Bioorganic & medicinal chemistry letters.

Cyanopyridyl containing 1,4-dihydroindeno[1,2-c]pyrazoles as potent checkpoint kinase 1 inhibitors: improving oral biovailability.

Philip J. Merta, Gaoquan Li, Z. Tao, 2007, Bioorganic & medicinal chemistry letters.

Discovery of 4'-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-benzonitriles and 4'-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-pyridine-2'-carbonitriles as potent checkpoint kinase 1 (Chk1) inhibitors.

Philip J. Merta, Gaoquan Li, Z. Tao, 2007, Bioorganic & medicinal chemistry letters.

Isoxazolo[3,4-b]quinoline-3,4(1H,9H)-diones as unique, potent and selective inhibitors for Pim-1 and Pim-2 kinases: chemistry, biological activities, and molecular modeling.

Eric F. Johnson, N. Soni, V. Giranda, 2008, Bioorganic & medicinal chemistry letters.

Constrained Peptidomimetics for TRH: cis-Peptide Bond Analogs

Garland R. Marshall, Marvin C. Gershengorn, Kevin D. Moeller, 2000 .

Azaindole-Based Inhibitors of Cdc7 Kinase: Impact of the Pre-DFG Residue, Val 195.

K. Swinger, Eric F. Johnson, N. Soni, 2013, ACS medicinal chemistry letters.

Aminopyrimidinone cdc7 kinase inhibitors.

Eric F. Johnson, N. Soni, J. Miyashiro, 2012, Bioorganic & medicinal chemistry letters.

Conformationally constrained substance P analogues: the total synthesis of a constrained peptidomimetic for the Phe7-Phe8 region.

Y. Tong, Y. M. Fobian, K. Moeller, 2000, The Journal of organic chemistry.

Conformational probes for elucidating the nature of substance P binding to the NK1 receptor: initial efforts to map the Phe7-Phe8 region.

Y. Tong, Y. M. Fobian, K. Moeller, 1998, Bioorganic & medicinal chemistry letters.

Design, synthesis, and biological activity of 4-[(4-cyano-2-arylbenzyloxy)-(3-methyl-3H-imidazol-4-yl)methyl]benzonitriles as potent and selective farnesyltransferase inhibitors.

V. Stoll, Y. Tong, Haiying Zhang, 2004, Journal of medicinal chemistry.

Anodic Electrochemistry: Recent Advances in the Total Synthesis of Complex Organic Molecules

Y. Tong, K. Moeller, D. Frey, 1998 .

Selective Chk1 inhibitors differentially sensitize p53‐deficient cancer cells to cancer therapeutics

Zhan Xiao, John Xue, Saul H Rosenberg, 2006, International journal of cancer.

A novel CDK9 inhibitor increases the efficacy of venetoclax (ABT-199) in multiple models of hematologic malignancies

M. Konopleva, T. Penning, Y. Tong, 2019, Leukemia.

Discovery of 1,4-dihydroindeno[1,2-c]pyrazoles as a novel class of potent and selective checkpoint kinase 1 inhibitors.

Chang Park, Saul H Rosenberg, Y. Tong, 2007, Bioorganic & medicinal chemistry.

CDK9 Inhibition Reverses Resistance to ABT-199 (GDC-0199) By Down-Regulating MCL-1

T. Penning, Y. Tong, J. Leverson, 2014 .

Synthesis and evaluation of a new generation of orally efficacious benzimidazole-based poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors as anticancer agents.

P. Ellis, Eric F. Johnson, N. Soni, 2009, Journal of medicinal chemistry.

1,4-Dihydroindeno[1,2-c]pyrazoles as potent checkpoint kinase 1 inhibitors: extended exploration on phenyl ring substitutions and preliminary ADME/PK studies.

Philip J. Merta, Z. Tao, Y. Tong, 2007, Bioorganic & medicinal chemistry letters.

Discovery of potent imidazole and cyanophenyl containing farnesyltransferase inhibitors with improved oral bioavailability.

V. Stoll, Y. Tong, Haiying Zhang, 2003, Bioorganic & medicinal chemistry letters.

Balancing Properties with Carboxylates: A Lead Optimization Campaign for Selective and Orally Active CDK9 Inhibitors.

K. Longenecker, T. Penning, Y. Tong, 2021, ACS medicinal chemistry letters.

Pyrimidine-based tricyclic molecules as potent and orally efficacious inhibitors of wee1 kinase.

K. Bromberg, Eric F. Johnson, N. Soni, 2015, ACS medicinal chemistry letters.

Pyrimidine-based tricyclic molecules as potent and orally efficacious inhibitors of wee1 kinase.

K. Bromberg, Eric F. Johnson, N. Soni, 2015, ACS medicinal chemistry letters.