D. Leach

发表

Advances in Brief Negative Regulation of Weel Expression and Cdc 2 Phosphorylation during p 53-mediated Growth Arrest and Apoptosis 1

Caroline, S. Song, Steven, 2006 .

The prognostic value of stromal FK506‐binding protein 1 and androgen receptor in prostate cancer outcome

G. Buchanan, D. Leach, G. Risbridger, 2017, The Prostate.

Peroxidase enzymes inhibit osteoclast differentiation and bone resorption

A. Evdokiou, D. Leach, V. Panagopoulos, 2017, Molecular and Cellular Endocrinology.

Roles of steroid receptors in the lung and COVID-19

D. Leach, C. Bevan, G. Brooke, 2021, Essays in biochemistry.

The unique transcriptional response produced by concurrent estrogen and progesterone treatment in breast cancer cells results in upregulation of growth factor pathways and switching from a Luminal A to a Basal-like subtype

J. Graham, G. Buchanan, L. Selth, 2015, BMC Cancer.

Uncovering a new role for peroxidase enzymes as drivers of angiogenesis.

A. Evdokiou, D. Leach, V. Panagopoulos, 2015, The international journal of biochemistry & cell biology.

Identification of transcription factor co-regulators that drive prostate cancer progression

E. Mathé, M. Campbell, D. Leach, 2020, Scientific Reports.

Genome-wide analyses of transcription factors and co-regulators across seven cohorts identified reduced PPARGC1A expression as a driver of prostate cancer progression

E. Mathé, M. Campbell, D. Leach, 2020, bioRxiv.

Myofibroblast androgen receptor expression determines cell survival in co-cultures of myofibroblasts and prostate cancer cells in vitro

D. Leach, P. Drew, Eric Smith, 2018, Oncotarget.

Cellular specificity of androgen receptor, coregulators, and pioneer factors in prostate cancer

D. Leach, C. Bevan, Rayzel C. Fernandes, 2022, Endocrine oncology.

TMPRSS2, required for SARS-CoV-2 entry, is downregulated in lung cells by enzalutamide, a prostate cancer therapeutic

D. Leach, C. Bevan, G. Brooke, 2020 .

Androgen Receptor and Androgen-Responsive Gene FKBP5 Are Independent Prognostic Indicators for Esophageal Adenocarcinoma

D. Leach, T. Underwood, A. Ruszkiewicz, 2016, Digestive Diseases and Sciences.

Liver Microenvironment Response to Prostate Cancer Metastasis and Hormonal Therapy

D. Leach, C. Bevan, Alison Buxton, 2022, Cancers.

Cell-lineage specificity and role of AP-1 in the prostate fibroblast androgen receptor cistrome

A. Thomson, G. Buchanan, L. Selth, 2017, Molecular and Cellular Endocrinology.

J. Graham, G. Buchanan, L. Selth, 2015, BMC Cancer.

A non-coding RNA balancing act: miR-346-induced DNA damage is limited by the long non-coding RNA NORAD in prostate cancer

D. Leach, K. Knudsen, T. Constantin, 2022, Molecular cancer.

p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells

Simak Ali, R. Coombes, M. Periyasamy, 2017, Nucleic acids research.

University of Dundee p 53 controls expression of the DNA deaminase APOBEC 3 B to limit its potential mutagenic activity in cancer cells

Simak Ali, M. Periyasamy, F. Fuller-Pace, 2017 .

Androgen receptor-modulatory microRNAs provide insight into therapy resistance and therapeutic targets in advanced prostate cancer

S. McGuire, X. Gidrol, D. Leach, 2019, Oncogene.

WOMEN IN CANCER THEMATIC REVIEW: New roles for nuclear receptors in prostate cancer.

D. Leach, C. Bevan, S. Powell, 2016, Endocrine-related cancer.

The antiandrogen enzalutamide downregulates TMPRSS2 and reduces cellular entry of SARS-CoV-2 in human lung cells

D. Leach, W. Barclay, L. Yates, 2021, Nature Communications.

Enzalutamide, a prostate cancer therapeutic, downregulates TMPRSS2 in lung and reduces cellular entry of SARS-CoV-2

D. Leach, W. Barclay, L. Yates, 2021 .

Hic-5 influences genomic and non-genomic actions of the androgen receptor in prostate myofibroblasts

D. DeFranco, G. Buchanan, D. Leach, 2014, Molecular and Cellular Endocrinology.

Stromal Androgen Receptor in Prostate Cancer Development and Progression

G. Buchanan, D. Leach, Grant Buchanan, 2017, Cancers.

Stromal androgen receptor regulates the composition of the microenvironment to influence prostate cancer outcome

C. Pinnock, D. DeFranco, G. Buchanan, 2015, Oncotarget.

Protocols for Studies on Stromal Cells in Prostate Cancer.

G. Buchanan, D. Leach, Grant Buchanan, 2018, Methods in molecular biology.

Inflammatory peroxidases promote breast cancer progression in mice via regulation of the tumour microenvironment.

V. Ponomarev, A. Evdokiou, D. Leach, 2017, International journal of oncology.

VDR Activity Is Differentially Affected by Hic-5 in Prostate Cancer and Stromal Cells

D. DeFranco, G. Buchanan, D. Leach, 2014, Molecular Cancer Research.

Molecular and structural basis of androgen receptor responses to dihydrotestosterone, medroxyprogesterone acetate and Δ4-tibolone

G. Buchanan, L. Butler, T. Bianco-Miotto, 2014, Molecular and Cellular Endocrinology.

Knockdown of the cochaperone SGTA results in the suppression of androgen and PI3K/Akt signaling and inhibition of prostate cancer cell proliferation

G. Coetzee, C. Pinnock, G. Buchanan, 2013, International journal of cancer.

Apoptosis-modulatory miR-361-3p as a novel treatment target in endocrine-responsive and endocrine-resistant breast cancer

X. Gidrol, D. Leach, S. Combe, 2023, The Journal of endocrinology.

AMPK activation protects against prostate cancer by inducing a catabolic cellular state.

D. Leach, A. Nikitin, Alice E. Pollard, 2023, Cell reports.

A non-coding RNA balancing act: miR-346-induced DNA damage is limited by the long non-coding RNA NORAD in prostate cancer

D. Leach, K. Knudsen, T. Constantin, 2022, Molecular Cancer.

Myofibroblast androgen receptor expression determines cell survival in co-cultures of myofibroblasts and prostate cancer cells in vitro

D. Leach, P. Drew, Eric Smith, 2018, OncoTarget.

Molecular and structural basis of androgen receptor responses to dihydrotestosterone, medroxyprogesterone acetate and Δ4-tibolone

L. Butler, T. Bianco-Miotto, E. Swinstead, 2014, Molecular and Cellular Endocrinology.

Cell-lineage specificity and role of AP-1 in the prostate fibroblast androgen receptor cistrome

A. Thomson, L. Selth, D. Leach, 2017, Molecular and Cellular Endocrinology.