M. Jung

发表

Human Squamous Carcinoma Cells Gene in Radiation-sensitive and-resistant p 53 Mutations in the Updated Version

M. Jung, V. Notario, A. Dritschilo, 2006 .

Regulation of p53 in response to ionizing radiation in ataxia telangiectasia fibroblasts.

M. Jung, A. Dritschilo, S. Lee, 1997, International journal of radiation oncology, biology, physics.

p53-Independent tumorigenic progression of human prostate cells.

M. Kuettel, M. Jung, A. Dritschilo, 1997, Radiation oncology investigations.

Ataxia telangiectasia and signal transduction

M. Jung, 1996 .

Elongation Factor 1δ Is Enhanced following Exposure to Ionizing Radiation

M. Jung, A. Dritschilo, A. Kondratyev, 1994 .

Fibroblast growth factor-4 enhanced G2 arrest and cell survival following ionizing radiation.

S. McLeskey, M. Jung, A. Dritschilo, 1994, Cancer research.

Mutations in the p53 gene in radiation-sensitive and -resistant human squamous carcinoma cells.

M. Jung, V. Notario, A. Dritschilo, 1992, Cancer research.

Complex formation of p65/RelA with nuclear Akt1 for enhanced transcriptional activation of NF-kappaB.

M. Jung, O. Kwon, Kyung Ah Kim, 2008, Biochemical and biophysical research communications.

Chemistry and biology of mercaptoacetamides as novel histone deacetylase inhibitors.

M. Jung, A. Dritschilo, A. Kozikowski, 2005, Bioorganic & medicinal chemistry letters.

Phenylalanine-containing hydroxamic acids as selective inhibitors of class IIb histone deacetylases (HDACs).

W. Sippl, E. Verdin, M. Jung, 2008, Bioorganic & medicinal chemistry.

Ataxia telangiectasia mutated down-regulates phospho-extracellular signal-regulated kinase 1/2 via activation of MKP-1 in response to radiation.

S. Varambally, A. Chinnaiyan, F. Feng, 2006, Cancer research.

Omics-based molecular target and biomarker identification.

Zhang-Zhi Hu, Cathy H. Wu, Hongzhan Huang, 2011, Methods in molecular biology.

Interstitial gene delivery in human xenograft prostate tumors using titanium metal seeds.

M. Jung, A. Dritschilo, Yin Zhang, 2004, Molecular cancer therapeutics.

Pharmacokinetics-pharmacodynamics and antitumor activity of mercaptoacetamide-based histone deacetylase inhibitors

M. Jung, A. Velena, H. Cao, 2009, Molecular Cancer Therapeutics.

Gene therapy for prostate cancer by targeting poly(ADP-ribose) polymerase.

V. Soldatenkov, M. Jung, A. Dritschilo, 2002, Cancer Research.

Poly(ADP-ribosyl)ation of p53 in vitro and in vivo modulates binding to its DNA consensus sequence.

M. Jung, A. Dritschilo, C. Simbulan-Rosenthal, 2001, Neoplasia.

Analysis of LC-MS data for characterizing the metabolic changes in response to radiation.

Leepika Tuli, Rency S Varghese, Amrita Cheema, 2010, Journal of proteome research.

Functional Proteomics Analysis to Study ATM Dependent Signaling in Response to Ionizing Radiation

H. Ressom, A. Cheema, M. Jung, 2013, Radiation research.

DLC-1, a GTPase-activating protein for Rho, is associated with cell proliferation, morphology, and migration in human hepatocellular carcinoma.

Jung Weon Lee, Y. Bang, M. Jung, 2007, Biochemical and biophysical research communications.

The Nucleoside Analog Sangivamycin Induces Apoptotic Cell Death in Breast Carcinoma MCF7/Adriamycin-resistant Cells via Protein Kinase Cδ and JNK Activation*

M. Jung, Sung A Lee, Sung A. Lee, 2007, Journal of Biological Chemistry.

Radiation-generated short DNA fragments may perturb non-homologous end-joining and induce genomic instability.

M. Jung, A. Dritschilo, B. Haddad, 2011, Journal of radiation research.

Altered expression of gamma-synuclein and detoxification-related genes in lungs of rats exposed to JP-8.

M. Jung, M. Smulson, L. A. Espinoza, 2005, American journal of respiratory cell and molecular biology.

African-American Prostate Normal and Cancer Cells for Health Disparities Research.

J. Rhim, M. Jung, A. Dritschilo, 2019, Advances in experimental medicine and biology.

Enhanced radiation late effects and cellular radiation sensitivity in an ATM heterozygous breast cancer patient.

R. Schmidt-Ullrich, M. Jung, A. Dritschilo, 1999, Radiation oncology investigations.

ATM blocks tunicamycin‐induced endoplasmic reticulum stress

M. Jung, O. Kwon, Long He, 2009, FEBS letters.

Impaired Ionizing Radiation-induced Activation of a Nuclear Signal Essential for Phosphorylation of c-Jun by Dually Phosphorylated c-Jun Amino-terminal Kinases in Ataxia Telangiectasia Fibroblasts*

M. Jung, A. Dritschilo, Sung A. Lee, 1998, The Journal of Biological Chemistry.

Enhanced expression of SOS1 is detected in prostate cancer epithelial cells from African-American men.

J. Rhim, H. Ressom, A. Cheema, 2009, International journal of oncology.

Transcriptional induction of DLC-1 gene through Sp1 sites by histone deacetylase inhibitors in gastric cancer cells

Jung Weon Lee, Y. Bang, Tae-You Kim, 2008, Experimental & Molecular Medicine.

Human prostate epithelial cell model system for carcinogenic studies

J. Rhim, M. Kuettel, P. Thraves, 1995 .

Adamantanyl-histone deacetylase inhibitor H6CAHA exhibits favorable pharmacokinetics and augments prostate cancer radiation sensitivity.

M. Jung, A. Velena, H. Cao, 2011, International journal of radiation oncology, biology, physics.

Identification of gene(s) involved in carcinogenic progression of ataxia telangiectasia cells

M. Jung, A. Dritschilo, Yin Zhang, 1995 .

Modification of ataxia telangiectasia cellular radiation sensitivity and resistant dna synthesis by transformation with episomally maintained vectors

M. Jung, A. Dritschilo, F. Kern, 1994 .

Modulation of E-cadherin expression by K-Ras; involvement of DNA methyltransferase-3b.

M. Jung, O. Kwon, Long He, 2010, Carcinogenesis.

Sensing of Ionizing Radiation-induced DNA Damage by ATM through Interaction with Histone Deacetylase*

Yung-Hyun Choi, M. Jung, A. Dritschilo, 1999, The Journal of Biological Chemistry.

NF-κB signaling pathway as a target for human tumor radiosensitization

M. Jung, A. Dritschilo, 2001 .

Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells

Jung Weon Lee, Y. Bang, M. Jung, 2003, Oncogene.

The p65 subunit of nuclear factor-kappaB is a molecular target for radiation sensitization of human squamous carcinoma cells.

M. Jung, A. Dritschilo, Gun-Do Kim, 2004, Molecular cancer therapeutics.

Epigenetic Targets in Drug Discovery: Cell‐Based Assays for HDAC Inhibitor Hit Validation

M. Jung, A. Velena, Sung A. Lee, 2009 .

Identification and characterization of a radiation-inducible glycosylated human early-response gene.

M. Jung, A. Kondratyev, K. Chung, 1996, Cancer research.

Modification of the radiosensitivity of human testicular cancer cells by simian virus 40 sequences.

M. Jung, A. Dritschilo, 1994, Radiation research.

NF-kappaB inhibition increases chemosensitivity to trichostatin A-induced cell death of Ki-Ras-transformed human prostate epithelial cells.

M. Jung, Cheorl-Ho Kim, Gun-Do Kim, 2006, Carcinogenesis.

NF-kappaB inhibition radiosensitizes Ki-Ras-transformed cells to ionizing radiation.

M. Jung, Gun-Do Kim, O. Kwon, 2005, Carcinogenesis.

Histone Deacetylases (HDAC)

M. Jung, A. Dritschilo, K. Unger, 2015 .

Construction of a Unidirectional cDNA Library from a Radioresistant Laryngeal Squamous Cell Carcinoma Cell Line in an Epstein Barr Virus Shuttle Vector

M. Jung, A. Dritschilo, F. Kern, 1991 .

Close yet so far away: a look into the management strategies of genetic imprinting disorders.

M. Jung, Pegah R Bakhshi, Alec T McIntosh, 2018, American journal of stem cells.

Role of p53 and ras genes in radiation‐induced transformation of immortalized human epidermal keratinocytes

J. Rhim, P. Thraves, M. Jung, 1994 .

Molecular and genetic characterization of human keratinocytes transformed with ionizing radiation

J. Rhim, P. Thraves, M. Jung, 1995 .

Irreversible binding of poly(ADP)ribose polymerase cleavage product to DNA ends revealed by atomic force microscopy: possible role in apoptosis.

A. Yakovlev, S. Chasovskikh, M. Jung, 1998, Cancer research.

Assays for histone deacetylases.

M. Jung, M. Jung, Alexander-Thomas Hauser, 2009, Current topics in medicinal chemistry.

Mercaptoacetamide-based class II HDAC inhibitor lowers Aβ levels and improves learning and memory in a mouse model of Alzheimer's disease

Raymond Scott Turner, M. Jung, Hyejin Yoon, 2013, Experimental Neurology.

Roles of poly(ADP-ribosyl)ation and PARP in apoptosis, DNA repair, genomic stability and functions of p53 and E2F-1.

A. Yakovlev, B. Stoica, A. Boulares, 2000, Advances in enzyme regulation.

Preclinical Studies of YK-4-272, an Inhibitor of Class II Histone Deacetylases by Disruption of Nucleocytoplasmic Shuttling

M. Jung, A. Dritschilo, Milton L. Brown, 2012, Pharmaceutical Research.

Role of ATM in Oxidative Stress-mediated c-Jun Phosphorylation in Response to Ionizing Radiation and CdCl2 *

M. Jung, A. Dritschilo, Sung A. Lee, 2001, The Journal of Biological Chemistry.

18Oxygen Substituted Nucleosides Combined with Proton Beam Therapy: Therapeutic Transmutation In Vitro

P. Stepanov, M. Jung, A. Dritschilo, 2021, International journal of particle therapy.

Cytoplasmic Sequestration of HDAC7 from Mitochondrial and Nuclear Compartments upon Initiation of Apoptosis*

M. Jung, R. Bakin, 2004, Journal of Biological Chemistry.

Radiation-induced Neoplastic Transformation of Human Prostate Epithelial Cells'

J. Rhim, M. Kuettel, P. Thraves, 2006 .

Enhancement of Radiation Sensitivity of Human Squamous Carcinoma Cells by Histone Deacetylase Inhibitors

M. Jung, A. Dritschilo, M. Jung, 2004, Radiation research.

In vitro plasma stability, permeability and solubility of mercaptoacetamide histone deacetylase inhibitors.

M. Jung, Roula Konsoula, 2008, International journal of pharmaceutics.

Ionizing Radiation-induced Apoptosis in Ataxia-Telangiectasia Fibroblasts

M. Jung, A. Dritschilo, Yin Zhang, 2001, The Journal of Biological Chemistry.

Ionizing radiation can induce GSK-3beta phosphorylation and NF-kappaB transcriptional transactivation in ATM-deficient fibroblasts.

M. Jung, O. Kwon, Kyung Ah Kim, 2008, Cellular signalling.

Constitutive activation of NF-κB in Ki-ras-transformed prostate epithelial cells

R. Gaynor, M. Jung, A. Dritschilo, 2002, Oncogene.

Epiregulin expression by Ets-1 and ERK signaling pathway in Ki-ras-transformed cells.

D. Yoon, Sue-N. Park, M. Jung, 2008, Biochemical and biophysical research communications.

Knockdown of EphB1 receptor decreases medulloblastoma cell growth and migration and increases cellular radiosensitization

T. MacDonald, M. Kool, S. Karam, 2015, Oncotarget.

Müllerian Inhibiting Substance Inhibits Breast Cancer Cell Growth through an NFκB-mediated Pathway*

P. Donahoe, S. Maheswaran, D. Segev, 2000, The Journal of Biological Chemistry.

Signal‐transduction pathways in androgen‐dependent and androgen‐independent prostate tumor cells

M. Jung, P. Ramsamooj, 1995 .

Attenuated DNA Damage Repair by Trichostatin A through BRCA1 Suppression

M. Jung, A. Dritschilo, Yin Zhang, 2007, Radiation research.

Ku proteins join DNA fragments as shown by atomic force microscopy.

M. Jung, A. Dritschilo, W. Dynan, 1997, Cancer research.

Rational Design and Development of Radiation‐Sensitizing Histone Deacetylase Inhibitors

M. Jung, A. Dritschilo, A. Kozikowski, 2005, Chemistry & biodiversity.

Novel HDAC Inhibitors with Radiosensitizing Properties

Bin Chen, M. Jung, A. Dritschilo, 2005, Radiation research.

Tissue ischemia time affects gene and protein expression patterns within minutes following surgical tumor excision.

H. Juhl, C. Zornig, K. David, 2004, BioTechniques.

A novel ionizing radiation-induced signaling pathway that activates the transcription factor NF-κB

Mira Jung, Anatoly Dritschilo, Su-Jae Lee, 1998, Oncogene.

Correction of radiation sensitivity in ataxia telangiectasia cells by a truncated I kappa B-alpha.

M. Jung, A. Dritschilo, Y. Zhang, 1995, Science.

ATM gene product phosphorylates I kappa B-alpha.

M. Jung, A. Dritschilo, S. Lee, 1997, Cancer research.

Integrated analysis of ATM mediated gene and protein expression impacting cellular metabolism.

H. Ressom, V. Shulaev, A. Cheema, 2011, Journal of proteome research.

Integrated Bioinformatics for Radiation-Induced Pathway Analysis from Proteomics and Microarray Data.

Zhang-Zhi Hu, Cathy H. Wu, Hongzhan Huang, 2008, Journal of proteomics & bioinformatics.

Expression of a dominant negative IκB-α modulates hypersensitivity of ataxia telangiectasia fibroblasts to streptonigrin-induced apoptosis

M. Jung, A. Dritschilo, Yin Zhang, 1997 .

Overexpression of Rb and E2F-1 in ataxia-telangiectasia lymphocytes

M. Jung, M. Jung, S. Varghese, 1998, Archives of pharmacal research.

Elevated frequency of ATM gene missense mutations in breast cancer relative to ethnically matched controls.

W. Bennett, M. Jung, A. Dritschilo, 2002, Cancer genetics and cytogenetics.

Human fibroblasts for large-scale "omics" investigations of ATM gene function.

H. Ressom, A. Cheema, M. Jung, 2011, Advances in experimental medicine and biology.

Reliable and efficient direct sequencing of PCR-amplified double-stranded genomic DNA template.

M. Jung, A. Dritschilo, U. Kasid, 1992, PCR methods and applications.

Histone deacetylase inhibitor: antineoplastic agent and radiation modulator.

M. Jung, A. Dritschilo, A. Velena, 2011, Advances in experimental medicine and biology.

Involvement of P-glycoprotein and multidrug resistance associated protein 1 on the transepithelial transport of a mercaptoacetamide-based histone-deacetylase inhibitor in Caco-2 cells.

M. Jung, Zacharoula Konsoula, 2009, Biological & pharmaceutical bulletin.

NF-κB inhibition radiosensitizes Ki-Ras-transformed cells to ionizing radiation

M. Jung, Gun-Do Kim, O. Kwon, 2005 .

Gene expression profile by inhibiting Raf-1 protein kinase in breast cancer cells.

M. Jung, A. Dritschilo, S. Tian, 2006, International journal of molecular medicine.

ATM missense mutations are frequent in patients with breast cancer.

M. Jung, A. Dritschilo, S. Sommer, 2003, Cancer genetics and cytogenetics.

Impaired regulation of nuclear factor-kappaB results in apoptosis induced by gamma radiation.

M. Jung, A. Dritschilo, Y. Zhang, 1998, Radiation research.

A Mercaptoacetamide‐Based Class II Histone Deacetylase Inhibitor Suppresses Cell Migration and Invasion in Monomorphic Malignant Human Glioma Cells by Inhibiting FAK/STAT3 Signaling

Young-Chae Chang, M. Jung, Keetae Kim, 2017, Journal of cellular biochemistry.

Histone Deacetylase Cytoplasmic Trapping by a Novel Fluorescent HDAC Inhibitor

S. Dakshanamurthy, M. Jung, A. Dritschilo, 2011, Molecular Cancer Therapeutics.

Characterization of novel inhibitors of histone acetyltransferases

Manfred Jung, M. Jung, M. Jung, 2007, Molecular Cancer Therapeutics.

Enhanced expression of SOS 1 is detected in prostate cancer epithelial cells from African-American men

J. Rhim, H. Ressom, A. Cheema, 2022 .

NF-kappa B signaling pathway as a target for human tumor radiosensitization.

M. Jung, A. Dritschilo, 2001, Seminars in radiation oncology.

A Mercaptoacetamide-Based Class II Histone Deacetylase Inhibitor Increases Dendritic Spine Density via RasGRF1/ERK Pathway.

D. Pak, M. Jung, Hyejin Yoon, 2016, Journal of Alzheimer's disease : JAD.

NF-κB inhibition increases chemosensitivity to trichostatin A-induced cell death of Ki-Ras-transformed human prostate epithelial cells

M. Jung, Cheorl-Ho Kim, Gun-Do Kim, 2006 .

NF-k B inhibition increases chemosensitivity to trichostatin A-induced cell death of Ki-Ras-transformed human prostate epithelial cells

M. Jung, Cheorl-Ho Kim, Gun-Do Kim, 2006 .

Combining radiation therapy with interstitial radiation-inducible TNF-α expression for locoregional cancer treatment

M. Jung, A. Dritschilo, A. Velena, 2011, Cancer Gene Therapy.

Identification of multiple repeat sequences and transcription-related elements within introns 4, 8 and 9 of human Raf-1.

M. Jung, A. Dritschilo, U. Kasid, 1993, Biochemical and biophysical research communications.

NF-kappaB inhibition enhances caspase-3 degradation of Akt1 and apoptosis in response to camptothecin.

A. Moon, M. Jung, O. Kwon, 2007, Cellular signalling.

HDAC2 Cytoplasmic Sequestration Potentiates Keratinocyte Terminal Differentiation

M. Jung, R. Bakin, 2008 .

Novel Inhibitors of Human Histone Deacetylase (HDAC) Identified by QSAR Modeling of Known Inhibitors, Virtual Screening, and Experimental Validation

Hao Tang, Xi-Ping Huang, Bryan L. Roth, 2009, J. Chem. Inf. Model..