P. Woster

发表

Role of p53/p21Waf1/Cip1 in the regulation of polyamine analogue-induced growth inhibition and cell death in human breast cancer cells

S. Sukumar, L. Marton, N. Davidson, 2005 .

Significance of targeting polyamine metabolism as an antineoplastic strategy: unique targets for polyamine analogues.

P. Woster, R. Casero, B. Frydman, 2005, Proceedings of the Western Pharmacology Society.

6′,7′‐Dihydroxybergamottin in grapefruit juice and Seville orange juice: Effects on cyclosporine disposition, enterocyte CYP3A4, and P‐glycoprotein

P. Watkins, E. Schuetz, P. Woster, 1999, Clinical pharmacology and therapeutics.

Novel Therapeutics Targeting Epigenetics

P. Woster, 2017 .

Inhibition of the LSD 1 ( KDM 1 A ) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia

Arthur, J. Dick, M. Minden, 2013 .

Selective targeting of CD38 hydrolase and cyclase activity as an approach to immunostimulation

Y. Peterson, P. Woster, N. Dolloff, 2021, RSC advances.

A novel histone deacetylase inhibitor prevents IL‐1β induced metabolic dysfunction in pancreatic β‐cells

P. Woster, A. Kowluru, Anjaneyulu Kowluru, 2009, Journal of cellular and molecular medicine.

Alkyl-substituted polyaminohydroxamic acids: a novel class of targeted histone deacetylase inhibitors.

P. Woster, S. Gore, R. Casero, 2005, Journal of medicinal chemistry.

Polyaminohydroxamic acids and polyaminobenzamides as isoform selective histone deacetylase inhibitors.

P. Woster, R. Casero, T. Murray-Stewart, 2008, Journal of medicinal chemistry.

Identification of 6',7'-dihydroxybergamottin, a cytochrome P450 inhibitor, in grapefruit juice.

P. Woster, D. Edwards, F. Bellevue, 1996, Drug metabolism and disposition: the biological fate of chemicals.

The role of polyamine catabolism in polyamine analogue-induced programmed cell death.

J. Yager, P. Woster, R. Casero, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Suppression of Exogenous Gene Expression by Spermidine/Spermine N1-Acetyltransferase 1 (SSAT1) Cotransfection*

P. Woster, R. Casero, Seung Bum Lee, 2010, The Journal of Biological Chemistry.

Antibacterial Diamines Targeting Bacterial Membranes.

P. Woster, Yong-mei Zhang, Michael G. Schmidt, 2016, Journal of medicinal chemistry.

OF ENHANCED ORAL AVAILABILITY OF CYP 3 A 4 SUBSTRATES BY GRAPEFRUIT CONSTITUENTS Decreased enterocyte CYP 3 A 4 concentration and mechanism-based inactivation by furanocoumarins

P. Watkins, P. Woster, K. Thummel, 1997 .

Synthesis and biological evaluation of 6',7'-dihydroxybergamottin (6,7-DHB), a naturally occurring inhibitor of cytochrome P450 3A4

P. Woster, K. He, David Edwards, 1997 .

A small molecule polyamine oxidase inhibitor blocks androgen-induced oxidative stress and delays prostate cancer progression in the transgenic adenocarcinoma of the mouse prostate model.

M. Lindstrom, G. Wilding, T. Thompson, 2009, Cancer research.

Polyamine catabolism and oxidative damage

P. Woster, R. Casero, T. Dunston, 2018, The Journal of Biological Chemistry.

Targeting polyamine metabolism for cancer therapy and prevention.

P. Woster, R. Casero, T. Murray-Stewart, 2016, The Biochemical journal.

acetyltransferase activity increases susceptibility to skin carcinogenesis

P. Woster, A. Pegg, C. Coleman, 2007 .

Studies of the mechanism by which increased spermidine/spermine N1-acetyltransferase activity increases susceptibility to skin carcinogenesis.

P. Woster, A. Pegg, C. Coleman, 2007, Carcinogenesis.

Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide

J. E. Rider, P. Woster, A. Pegg, 2007, Amino Acids.

Transcriptional Activity of the Islet β Cell Factor Pdx1 Is Augmented by Lysine Methylation Catalyzed by the Methyltransferase Set7/9*

A. Mosley, R. Stein, P. Woster, 2015, The Journal of Biological Chemistry.

Advances in Brief Induction of Programmed Cell Death in Human Breast Cancer Cells by an Unsymmetrically Alkylated Polyamine Analogue 1

N. Davidson, P. Woster, R. Casero, 2006 .

Polyamine analogue induction of programmed cell death in human lung tumor cells.

N. Davidson, P. Woster, R. Casero, 1996, Clinical cancer research : an official journal of the American Association for Cancer Research.

Induction of programmed cell death in human breast cancer cells by an unsymmetrically alkylated polyamine analogue.

N. Davidson, P. Woster, R. Casero, 1995, Cancer research.

Combination of standard cytotoxic agents with polyamine analogues in the treatment of breast cancer cell lines.

N. Davidson, P. Woster, R. Casero, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Mitochondrial depolarization after acute ethanol treatment drives mitophagy in living mice

P. Woster, J. Lemasters, Y. Krishnasamy, 2022, Autophagy.

Polyamine-based analogues as biochemical probes and potential therapeutics.

P. Woster, R. Casero, S. Varghese, 2007, Biochemical Society transactions.

A Charge-Deficient Analogue of Spermine with Chelating Properties

P. Woster, R. Casero, A. V. Demin, 2005, Russian Journal of Bioorganic Chemistry.

The biguanide polyamine analog verlindamycin promotes differentiation in neuroblastoma via induction of antizyme

P. Woster, K. Barker, L. Howell, 2021, Cancer Gene Therapy.

Reactive oxygen species generation and its role in the differential cytotoxicity of the arylhydroxylamine metabolites of sulfamethoxazole and dapsone in normal human epidermal keratinocytes.

P. Woster, S. Roychowdhury, C. K. Svensson, 2005, Biochemical pharmacology.

Role of p53/p21(Waf1/Cip1) in the regulation of polyamine analogue-induced growth inhibition and cell death in human breast cancer cells.

S. Sukumar, L. Marton, N. Davidson, 2005, Cancer biology & therapy.

Chapter 10. New therapies for parasitic infection

P. Woster, 2001 .

Clinical aspects of cell death in breast cancer: the polyamine pathway as a new target for treatment.

N. Davidson, P. Woster, R. Casero, 1999, Endocrine-related cancer.

Minireview: Polyamine catabolism and oxidative damage

P. Woster, R. Casero, T. M. Stewart, 2018 .

Cloning and characterization of a human polyamine oxidase that is inducible by polyamine analogue exposure.

P. Woster, Y. Wang, R. Casero, 2001, Cancer research.

Cloning and Characterization of a Human Polyamine Oxidase That Is Inducible by Polyamine Analogue Exposure 1

P. Woster, R. Casero, T. M. Stewart, 2001 .

Cytotoxicity of novel unsymmetrically substituted inhibitors of polyamine biosynthesis in human cancer cells

P. Woster, H. Wallace, L. Nairn, 2000, Journal of cellular physiology.

Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia

Martin Dugas, Hans-Ulrich Klein, Kevin Petrie, 2012, Nature Medicine.

Induction of apoptosis in human leukaemic cells by IPENSpm, a novel polyamine analogue and anti-metabolite.

P. Woster, H. Wallace, A. Fraser, 2002, The Biochemical journal.

Detoxification of the polyamine analogue N1-ethyl-N11-[(cycloheptyl)methy]-4,8-diazaundecane (CHENSpm) by polyamine oxidase.

E. Gerner, P. Woster, C. Payne, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Spermine Oxidase SMO(PAOh1), Not N1-Acetylpolyamine Oxidase PAO, Is the Primary Source of Cytotoxic H2O2 in Polyamine Analogue-treated Human Breast Cancer Cell Lines*

Zhe Zhang, N. Davidson, Yi Huang, 2005, Journal of Biological Chemistry.

Structure-activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures.

Shiv k. Sharma, Yi Huang, P. Woster, 2015, Bioorganic & medicinal chemistry.

Growth and biochemical effects of unsymmetrically substituted polyamine analogues in human lung tumor cells 1

W. J. Dyer, P. Woster, R. Wu, 2004, Cancer Chemotherapy and Pharmacology.

1-(N-alkylamino)-11-(N-ethylamino)-4,8-diazaundecanes: simple synthetic polyamine analogues that differentially alter tubulin polymerization.

P. Woster, R. Casero, Z. Wu, 1999, Journal of medicinal chemistry.

Dual inhibitors of LSD1 and spermine oxidase.

Y. Peterson, P. Woster, R. Casero, 2019, MedChemComm.

Elevated ornithine decarboxylase activity promotes skin tumorigenesis by stimulating the recruitment of bulge stem cells but not via toxic polyamine catabolic metabolites

P. Woster, C. Hayes, S. Gilmour, 2014, Amino Acids.

Elevated ornithine decarboxylase activity promotes skin tumorigenesis by stimulating the recruitment of bulge stem cells but not via toxic polyamine catabolic metabolites

P. Woster, C. Hayes, S. Gilmour, 2013, Amino Acids.

Induction of human spermine oxidase SMO(PAOh1) is regulated at the levels of new mRNA synthesis, mRNA stabilization and newly synthesized protein.

P. Woster, R. Casero, T. Murray-Stewart, 2005, The Biochemical journal.

Identification and Characterization of Novel Small-Molecule SMOX Inhibitors

Y. Peterson, P. Woster, R. Casero, 2022, Medical sciences.

Synthesis and evaluation of unsymmetrically substituted polyamine analogues as modulators of human spermidine/spermine-N1-acetyltransferase (SSAT) and as potential antitumor agents.

P. Woster, R. Casero, A. Mank, 1993, Journal of medicinal chemistry.

Synthesis and evaluation of small molecule inhibitors of LSD1 for use against MYCN-expressing neuroblastoma.

D. Geerts, P. Woster, A. Bachmann, 2022, European journal of medicinal chemistry.

Synthesis of protected allylic amines via palladium(0)-catalyzed amination of allylic acetates

P. Woster, N. Sirisoma, 1998 .

(Bis)urea and (bis)thiourea inhibitors of lysine-specific demethylase 1 as epigenetic modulators.

Shiv k. Sharma, P. Woster, R. Casero, 2010, Journal of medicinal chemistry.

Chapter 21. New therapies for malaria

P. Woster, 2003 .

Bergamottin contribution to the grapefruit juice–felodipine interaction and disposition in humans

P. Woster, T. Goosen, L. Cohen, 2004, Clinical pharmacology and therapeutics.

Mechanism-based inhibitors of the aspartyl protease plasmepsin II as potential antimalarial agents.

P. Woster, L. Kovari, Deepak Gupta, 2010, Journal of medicinal chemistry.

Antiprotozoal/Antiparasitic Agents

P. Woster, 2010 .

Antiprotozoal Agents (African Trypanosomiasis, Chagas Disease, and Leishmaniasis)

P. Woster, 2007 .

Terminally alkylated polyamine analogues as chemotherapeutic agents.

P. Woster, R. Casero, 2001, Journal of medicinal chemistry.

Synthesis and evaluation of a polyamine phosphinate and phosphonamidate as transition-state analogue inhibitors of spermidine/spermine-N1-acetyltransferase.

R. Wu, P. Woster, A. Pegg, 1996, Bioorganic & medicinal chemistry.

Polyamines and cancer: implications for chemotherapy and chemoprevention

P. Woster, R. Casero, Robert A. Casero, 2013, Expert Reviews in Molecular Medicine.

The natural polyamine spermine functions directly as a free radical scavenger.

J. Zweier, P. Woster, P. Kuppusamy, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Polyamine Structure and Synthetic Analogs

P. Woster, 2006 .

Recent advances in the development of polyamine analogues as antitumor agents.

P. Woster, R. Casero, 2009, Journal of medicinal chemistry.

Discovery of novel alkylated (bis)urea and (bis)thiourea polyamine analogues with potent antimalarial activities.

Shiv k. Sharma, P. Woster, L. Birkholtz, 2011, Journal of medicinal chemistry.

Effect of pro-inflammatory cytokines on the toxicity of the arylhydroxylamine metabolites of sulphamethoxazole and dapsone in normal human keratinocytes.

P. Woster, F. Khan, S. Roychowdhury, 2006, Toxicology.

A role for bioactivation and covalent binding within epidermal keratinocytes in sulfonamide-induced cutaneous drug reactions.

P. Woster, L. Lash, M. Doll, 2000, The Journal of investigative dermatology.

Comparison of the in vitro cytotoxicity of hydroxylamine metabolites of sulfamethoxazole and dapsone.

P. Woster, T. Reilly, C. K. Svensson, 1998, Biochemical pharmacology.

Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins.

P. Watkins, P. Woster, K. He, 1997, Drug metabolism and disposition: the biological fate of chemicals.

Is hydroxylamine-induced cytotoxicity a valid marker for hypersensitivity reactions to sulfamethoxazole in human immunodeficiency virus-infected individuals?

P. Woster, R. MacArthur, T. Reilly, 1999, The Journal of pharmacology and experimental therapeutics.

Methemoglobin formation by hydroxylamine metabolites of sulfamethoxazole and dapsone: implications for differences in adverse drug reactions.

P. Woster, T. Reilly, C. K. Svensson, 1999, The Journal of pharmacology and experimental therapeutics.

Epigenetic Reexpression of Hemoglobin F Using Reversible LSD1 Inhibitors: Potential Therapies for Sickle Cell Disease

P. Woster, R. Casero, H. Hyacinth, 2020, ACS omega.

Polyamine metabolism in a member of the phylum Microspora (Encephalitozoon cuniculi): effects of polyamine analogues.

L. Marton, P. Woster, L. Weiss, 2004, Microbiology.

Novel alkylpolyamine analogues that possess both antitrypanosomal and antimicrosporidial activity.

P. Woster, L. Weiss, R. Casero, 2001, Bioorganic & medicinal chemistry letters.

Metabolism of an Alkyl Polyamine Analog by a Polyamine Oxidase from the Microsporidian Encephalitozoon cuniculi

P. Woster, L. Weiss, N. Yarlett, 2009, Antimicrobial Agents and Chemotherapy.

Polyamine analogues targeting epigenetic gene regulation.

L. Marton, Yi Huang, P. Woster, 2009, Essays in biochemistry.

The role of the polyamine catabolic enzymes SSAT and SMO in the synergistic effects of standard chemotherapeutic agents with a polyamine analogue in human breast cancer cell lines

Zhe Zhang, Michele D. Sobolewski, Zhe Zhang, 2010, Cancer Chemotherapy and Pharmacology.

S-(5'-deoxy-5'-adenosyl)-1-ammonio-4-(methylsulfonio)-2-cyclopentene: A potent, enzyme-activated irreversible inhibitor of S-adenosylmethionine decarboxylase.

P. Woster, Y. Wu, 1992, Journal of medicinal chemistry.

Interrogating alkyl and arylalkylpolyamino (bis)urea and (bis)thiourea isosteres as potent antimalarial chemotypes against multiple lifecycle forms of Plasmodium falciparum parasites.

T. Egan, P. Woster, L. Birkholtz, 2015, Bioorganic & medicinal chemistry.

Knockdown of ornithine decarboxylase antizyme 1 causes loss of uptake regulation leading to increased N1, N11-bis(ethyl)norspermine (BENSpm) accumulation and toxicity in NCI H157 lung cancer cells

E. Sugar, P. Woster, R. Casero, 2012, Amino Acids.

Irreversible inhibition of human S-adenosylmethionine decarboxylase by the pure diastereomeric forms of S-(5'-deoxy-5'-adenosyl)-1-ammonio-4- methylsulfonio-2-cyclopentene (AdoMac).

P. Woster, Y. Wu, 1995, Biochemical pharmacology.

α-cyano-substituted analogoues of decarboxylated S-adenosylmethionine as enzyme activated, irreversible inhibitors of S-adenosylmethionine decarboxylase

P. Woster, T. Lawrence, Junkai Guo, 1993 .

Preparation of the pure diastereomeric forms of S-(5'-deoxy-5'-adenosyl)-1-ammonio-4-methylsulfonio-2-cyclopentene and their evaluation as irreversible inhibitors of S-adenosylmethionine decarboxylase from Escherichia coli.

P. Woster, Y. Wu, 1993, Bioorganic & medicinal chemistry.

Growth status significantly affects the response of human lung cancer cells to antitumor polyamine-analogue exposure.

P. Woster, D. Carlisle, R. Casero, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Properties of recombinant human N1-acetylpolyamine oxidase (hPAO): potential role in determining drug sensitivity

P. Woster, R. Casero, B. Frydman, 2005, Cancer Chemotherapy and Pharmacology.

Properties of purified recombinant human polyamine oxidase, PAOh1/SMO.

P. Woster, R. Casero, B. Frydman, 2003, Biochemical and biophysical research communications.

Effects of the polyamine analogues N1-ethyl-N11-((cyclopropyl)methyl)-4,8-diazaundecane and N1-ethylN-11-((cycloheptyl)methyl)-4,8-diazaundecane in human prostate cancer cells.

N. Davidson, P. Woster, R. Casero, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Unsymmetrically substituted polyamine analogue induces caspase-independent programmed cell death in Bcl-2-overexpressing cells.

P. Woster, R. Casero, H. Ha, 1998, Cancer research.

Synthesis and biological evaluation of S-adenosyl-1,12-diamino-3-thio-9-azadodecane, a multisubstrate adduct inhibitor of spermine synthase.

P. Woster, A. Pegg, J. Coward, 1989, Journal of medicinal chemistry.

Restricted rotation analogs of decarboxylated S-adenosylmethionine as inhibitors of polyamine biosynthesis.☆

P. Woster, Kirk A. Douglas, Michele M. Zormeier, 1991 .

Restricted rotation analogs of S-adenosylmethionine: synthesis, evaluation as inhibitors of S-adenosylmethionine decarboxylase, and potential use as selective antitrypanosomal agents

P. Woster, Kirk A. Douglas, J. Garofalo, 1993 .

Increased Helicobacter pylori-associated gastric cancer risk in the Andean region of Colombia is mediated by spermine oxidase

T. A. Nagy, D. Morgan, L. Bravo, 2014, Oncogene.

The re-expression of the epigenetically silenced e-cadherin gene by a polyamine analogue lysine-specific demethylase-1 (LSD1) inhibitor in human acute myeloid leukemia cell lines

P. Woster, R. Casero, T. Murray-Stewart, 2014, Amino Acids.

Low molecular weight amidoximes that act as potent inhibitors of lysine-specific demethylase 1.

P. Woster, S. Hazeldine, R. Casero, 2012, Journal of medicinal chemistry.

Epigenetic Targets and Cancer Drug Discovery

P. Woster, 2010 .

Novel Oligoamine Analogues Inhibit Lysine-Specific Demethylase 1 and Induce Reexpression of Epigenetically Silenced Genes

S. Baylin, L. Marton, Richard J. Jones, 2009, Clinical Cancer Research.

Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes

S. Baylin, Yi Huang, P. Woster, 2007, Proceedings of the National Academy of Sciences.

Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells

L. Marton, N. Davidson, Yi Huang, 2012, Amino Acids.

Abstract 4877: Polyamine analogues modulate gene expression by inhibiting KDM1/LSD1 and altering chromatin structure in human breast cancer cells

L. Marton, N. Davidson, Yi Huang, 2010 .

Novel alkylpolyaminoguanidines and alkylpolyaminobiguanides with potent antitrypanosomal activity.

P. Woster, D. Rattendi, C. Bacchi, 2006, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of novel cyclic Peptide inhibitors of lysine-specific demethylase 1.

Isuru R. Kumarasinghe, P. Woster, 2014, ACS medicinal chemistry letters.

Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies

P. Woster, F. Giardiello, R. Casero, 2018, PloS one.

Spermine oxidase (SMO) activity in breast tumor tissues and biochemical analysis of the anticancer spermine analogues BENSpm and CPENSpm

P. Mariottini, E. Fratini, F. Polticelli, 2010, BMC Cancer.

Spermine analogue-regulated expression of spermidine/spermine N1-acetyltransferase and its effects on depletion of intracellular polyamine pools in mouse fetal fibroblasts.

L. Alhonen, P. Woster, P. Uimari, 2009, The Biochemical journal.

Design of small molecule epigenetic modulators.

P. Woster, Boobalan Pachaiyappan, 2014, Bioorganic & medicinal chemistry letters.

Dapsone-induced hematologic toxicity: comparison of the methemoglobin-forming ability of hydroxylamine metabolites of dapsone in rat and human blood.

P. Woster, C. K. Svensson, C. Vage, 1994, Toxicology and applied pharmacology.

Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis

P. Woster, D. Huso, C. Sears, 2011, Proceedings of the National Academy of Sciences.

Effect of S-adenosyl-1,12-diamino-3-thio-9-azadodecane, a multisubstrate adduct inhibitor of spermine synthase, on polyamine metabolism in mammalian cells.

P. Woster, A. Pegg, R. Wechter, 1989, Biochemistry.

Elevated ornithine decarboxylase levels activate ataxia telangiectasia mutated-DNA damage signaling in normal keratinocytes.

Gang Wei, P. Woster, L. Mandik-Nayak, 2008, Cancer research.

Alternative Spermidine Biosynthetic Route Is Critical for Growth of Campylobacter jejuni and Is the Dominant Polyamine Pathway in Human Gut Microbiota*

B. Pearson, M. Phillips, P. Woster, 2011, The Journal of Biological Chemistry.

Stimulation of natural killer cells with small molecule inhibitors of CD38 for the treatment of neuroblastoma

P. Woster, N. Dolloff, Thomas Z. Benton, 2023, Chemical science.

Spermine Oxidase Mediates Helicobacter pylori-induced Gastric Inflammation, DNA Damage, and Carcinogenic Signaling

Kristie L. Rose, J. Cleveland, A. Gobert, 2020, Oncogene.

Discovery of a new class of histone deacetylase inhibitors with a novel zinc binding group.

P. Woster, Youxuan Li, 2015, MedChemComm.

Inhibition of the histone demethylase KDM4B leads to activation of KDM1A, attenuates bacterial-induced pro-inflammatory cytokine release, and reduces osteoclastogenesis

P. Woster, K. Kirkwood, J. Kirkpatrick, 2018, Epigenetics.

Terminally Alkylated Polyamine Analogues as Chemotherapeutic Agents

P. Woster, R. Casero, 2001 .

Epigenetics: Novel Therapeutics Targeting Epigenetics.

W. Greenlee, P. Woster, G. Georg, 2015, Journal of medicinal chemistry.

3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors.

P. Woster, Patrick M Woster, Ethan A. Marrow, 2014, MedChemComm.

Polyamine-based small molecule epigenetic modulators.

Shiv k. Sharma, F. Hirata, Yi Huang, 2012, MedChemComm.

Novel Synthetic Polyamines Have Potent Antimalarial Activities in vitro and in vivo by Decreasing Intracellular Spermidine and Spermine Concentrations

R. Upadhya, Kami Kim, K. El Bissati, 2019, Front. Cell. Infect. Microbiol..

Histone Deacetylase Inhibition Overcomes Drug Resistance through a miRNA-Dependent Mechanism

L. Marton, P. Woster, Christin L. Hanigan, 2013, Molecular Cancer Therapeutics.

S-(5'-deoxy-5'-adenosyl)-1-aminoxy-4-(methylsulfonio)-2-cyclopentene (AdoMao): an irreversible inhibitor of S-adenosylmethionine decarboxylase with potent in vitro antitrypanosomal activity.

P. Woster, D. Rattendi, C. Bacchi, 1995, Journal of medicinal chemistry.

Inhibition of Polyamine Biosynthesis Using Difluoromethylornithine Acts as a Potent Immune Modulator and Displays Therapeutic Synergy With PD-1-blockade

P. Woster, E. Bartee, C. Fisher, 2021, Journal of immunotherapy.

Loss of LSD1 (lysine-specific demethylase 1) suppresses growth and alters gene expression of human colon cancer cells in a p53- and DNMT1(DNA methyltransferase 1)-independent manner

B. Park, Lihua Jin, P. Woster, 2012, The Biochemical journal.

Cyclic peptide inhibitors of lysine-specific demethylase 1 with improved potency identified by alanine scanning mutagenesis.

Isuru R. Kumarasinghe, P. Woster, 2018, European journal of medicinal chemistry.

Use of polyamine derivatives as selective histone deacetylase inhibitors.

P. Woster, 2011, Methods in molecular biology.

Epigenetics: novel therapeutics targeting epigenetics.

P. Woster, G. Georg, S. Conway, 2015, Journal of medicinal chemistry.

Design of polyamine-based therapeutic agents: new targets and new directions.

P. Woster, R. Casero, T. Boncher, 2009, Essays in biochemistry.

Cloning and characterization of the mouse polyamine-modulated factor-1 (mPMF-1) gene: an alternatively spliced homologue of the human transcription factor.

P. Woster, Y. Wang, R. Casero, 2001, The Biochemical journal.

Small molecules targeting the NADH-binding pocket of VDAC modulate mitochondrial metabolism in hepatocarcinoma cells

Y. Peterson, P. Woster, C. Kappler, 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

The role of polyamine catabolism in anti-tumour drug response.

P. Woster, Y. Wang, R. Smith, 2003, Biochemical Society transactions.

Aldehyde Dehydrogenase-2 activation by Alda-1 decreases necrosis and fibrosis after bile duct ligation in mice.

D. Rockey, P. Woster, J. Lemasters, 2019, Free radical biology & medicine.

Effects of the Polyamine AnaloguesN-Ethyl-N-((cyclopropyl)methyl)- 4,8-diazaundecane andN-Ethyl-N-((cycloheptyl)methyl)-4,8- diazaundecane in Human Prostate Cancer Cells

N. Davidson, P. Woster, R. Casero, 2000 .

Induction of the PAOh1/SMO polyamine oxidase by polyamine analogues in human lung carcinoma cells

L. Marton, P. Woster, R. Casero, 2003, Cancer Chemotherapy and Pharmacology.

Molecular basis for the polyamine-ompF porin interactions: inhibitor and mutant studies.

A. Delcour, P. Woster, R. Iyer, 2000, Journal of molecular biology.

Foreword: American Chemical Society Division of Medicinal Chemistry. Celebrating 100 years of excellence.

P. Woster, 2009, Journal of medicinal chemistry.

Structural comparison of alkylpolyamine analogues with potent in vitro antitumor or antiparasitic activity

P. Woster, R. Wu, R. Casero, 1996 .

Crystal structures of multidrug-resistant HIV-1 protease in complex with two potent anti-malarial compounds.

P. Woster, Zhigang Liu, Yong Wang, 2012, Biochemical and biophysical research communications.

Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide

P. Woster, R. Casero, A. Hacker, 2007, Amino Acids.