T. Ohtsubo

发表

P53-independent thermosensitization by mitomycin C in human non-small-cell lung cancer cells.

Z. Jin, H. Matsumoto, S. Hayashi, 2004, International journal of radiation oncology, biology, physics.

Cell cycle progression and apoptosis after irradiation in an acidic environment

T. Ohtsubo, H. Park, J. Lyons, 2000, Cell Death and Differentiation.

Acidic environment causes apoptosis by increasing caspase activity

T. Ohtsubo, H. Park, J. Lyons, 1999, British Journal of Cancer.

Acidic environment modifies heat- or radiation-induced apoptosis in human maxillary cancer cells.

H. Matsumoto, T. Ohtsubo, E. Kano, 2001, International journal of radiation oncology, biology, physics.

Expression of multidrug resistance protein 1 (MRP1) in the rat cochlea with special reference to the blood–inner ear barrier

T. Ohtsubo, Takehisa Saito, Zhi-jian Zhang, 2001, Brain Research.

Influence of platelet-derived endothelial cell growth factor/thymidine phosphorylase on the cell cycle in head and neck squamous cell carcinoma in vitro.

T. Ohtsubo, S. Fujieda, C. Sugimoto, 2003, Oncology reports.

Induction of radioresistance by a nitric oxide-mediated bystander effect

Z. Jin, H. Matsumoto, S. Hayashi, 2002 .

Induction of radioresistance to accelerated carbon-ion beams in recipient cells by nitric oxide excreted from irradiated donor cells of human glioblastoma.

T. Ohnishi, H. Matsumoto, S. Hayashi, 2000, International journal of radiation biology.

Fluorine-18-fluorodeoxyglucose PET versus thallium-201 scintigraphy evaluation of thyroid tumors.

N. Sadato, H. Saito, Satoshi Nakamura, 1998, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Effect of acidic environment and p53 on apoptosis induction by hyperthermia

T. Ohnishi, T. Ohtsubo, H. Park, 2000, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

p53-dependent induction of WAF1 by a low-pH culture condition in human glioblastoma cells.

A. Takahashi, T. Ohnishi, T. Ohtsubo, 1997, Cancer research.

EFFECTS OF CISPLATIN AND PHENYLETHYL ISOTHIOCYANATE ON HEAD AND NECK CANCER CELLS

T. Ohtsubo, S. Fujieda, H. Sunaga, 2001 .

Inhibition of N‐linked glycosylation by tunicamycin enhances sensitivity to cisplatin in human head‐and‐neck carcinoma cells

T. Ohtsubo, S. Fujieda, H. Tsuzuki, 1999, International journal of cancer.

Sensitization to hyperthermia by intracellular acidification of C6 glioma cells.

H. Matsumoto, S. Hayashi, T. Ohtsubo, 1998, Journal of neuro-oncology.

Inhibitory effect of cyclosporin A on p-Glycoprotein function in peripheral nerves of mice treated with doxorubicin and vinblastine

T. Ohtsubo, Takehisa Saito, Zhi-jian Zhang, 2004, Acta oto-laryngologica.

Cyclosporin A inhibits the extrusion pump function of p-glycoprotein in the inner ear of mice treated with vinblastine and doxorubicin

T. Ohtsubo, Takehisa Saito, Zhi-jian Zhang, 2001, Brain Research.

Homozygous disruption of the mdrla P-glycoprotein gene affects blood-nerve barrier function in mice administered with neurotoxic drugs.

T. Ohtsubo, T. Yamamoto, T. Saito, 2001, Acta oto-laryngologica.

Expression of P-glycoprotein in inner ear capillary endothelial cells of the guinea pig with special reference to blood–inner ear barrier

Zhi Jian Zhang, T. Ohtsubo, H. Tsuzuki, 1997, Brain Research.

P-glycoprotein expression in capillary endothelial cells of the 7th and 8th nerves of guinea pig in relation to blood–nerve barrier sites

Zhi Jian Zhang, T. Ohtsubo, Takehisa Saito, 1997, Neuroscience Letters.

Up-regulation of hMUTYH, a DNA repair enzyme, in the mitochondria of substantia nigra in Parkinson’s disease

N. Hattori, T. Hatano, Y. Nakabeppu, 2006, Acta Neuropathologica.

Suppression of heat-induced hsp72 accumulation by cisplatin in human glioblastoma cells.

T. Ohnishi, H. Matsumoto, T. Ohtsubo, 1996, Cancer letters.

Xanthine Oxidoreductase Is an Endogenous Regulator of Cyclooxygenase-2

Chengyu Liu, T. Ohtsubo, T. Finkel, 2004, Circulation research.

ENHANCED DRUG EFFLUX AND DNA REPAIR ABILITY IN A CISPLATIN-RESISTANT CARCINOMA CELL LINE

T. Ohtsubo, S. Fujieda, H. Tsuzuki, 1999 .

Xanthine Oxidoreductase Is a Regulator of Adipogenesis and PPARγ Activity

Kevin J. Cheung, J. Friedman, J. Flier, 2007 .

Enhancement of Cytotoxic Effects of Chemotherapeutic Agents with Hyperthermia In Vitro

H. Matsumoto, S. Hayashi, M. Hatashita, 2001 .

In vitro Effects of Hyperthermia Combined with Chemotherapeutic Agents

H. Matsumoto, S. Hayashi, M. Hatashita, 2000 .

Suppression of heat-induced p53 accumulation and activation by CDDP or x-rays in human glioblastoma cells.

T. Ohnishi, H. Matsumoto, S. Hayashi, 1998, International journal of oncology.

EFFECT OF G-CSF ON TUMOR INVASION OF MAXILLARY CANCER CELL LINES

T. Ohtsubo, H. Tsuzuki, C. Sugimoto, 1996 .

Effects of cis-diamminedichloroplatinum (CDDP) and cis-diammine (1,1-cyclobutanedicarboxylate) platinum (CBDCA) on thermotolerance development and thermosensitivity of the thermotolerant cells.

T. Ohtsubo, E. Kano, H. Saito, 1990, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

The effect of sodium thiosulfate on ototoxicity and pharmacokinetics after cisplatin treatment in guinea pigs

T. Ohtsubo, T. Saito, H. Saito, 2008, European Archives of Oto-Rhino-Laryngology.

Suppression of heat-induced HSF activation by CDDP in human glioblastoma cells.

T. Ohnishi, H. Matsumoto, S. Hayashi, 1998, International journal of radiation oncology, biology, physics.

Xanthine oxidoreductase is a regulator of adipogenesis and PPARgamma activity.

Kevin J. Cheung, J. Friedman, J. Flier, 2007, Cell metabolism.

Fundamental Aspects of Hyperthermia on Cellular and Molecular Levels

H. Matsumoto, S. Hayashi, M. Hatashita, 2001 .

Nitric oxide is an initiator of intercellular signal transduction for stress response after hyperthermia in mutant p53 cells of human glioblastoma.

T. Ohnishi, H. Matsumoto, S. Hayashi, 1999, Cancer research.

Intercellular signaling initiated by nitric oxide produced in heat-shocked human glioblastoma cells.

T. Ohnishi, H. Matsumoto, S. Hayashi, 1999, Nitric oxide : biology and chemistry.

Granulocyte‐colony‐stimulating factor enhances invasive potential of human head‐and‐neck‐carcinoma cell lines

H. Saito, T. Ohtsubo, S. Fujieda, 1999, International journal of cancer.

Clinical application of chemosensitivity test for head and neck tumor

T. Ohtsubo, S. Fujieda, G. Tsuda, 1991 .

Enhancement of Cell Killing by Induction of Apoptosis after Treatment with Mild Hyperthermia at 42°C and Cisplatin

H. Matsumoto, T. Ohtsubo, E. Kano, 2001 .

Prevention of persistent ear drum perforation after long-term ventilation tube treatment for otitis media with effusion in children.

T. Ohtsubo, T. Yamamoto, T. Saito, 1996, International journal of pediatric otorhinolaryngology.

Recent Outcome of Tympanoplasty in the Elderly

H. Saito, T. Ohtsubo, Takehisa Saito, 2001, Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.

Free peroneal skin flap for oropharyngeal reconstruction.

T. Ohtsubo, S. Fujieda, G. Tsuda, 1999, Scandinavian journal of plastic and reconstructive surgery and hand surgery.

Morphological and Functional Study of Regenerated Chorda Tympani Nerves in Humans

T. Ohtsubo, Takehisa Saito, Y. Manabe, 2000, The Annals of otology, rhinology, and laryngology.

Free peroneal and its composite flap: a distant donor for head and neck reconstruction.

T. Ohtsubo, S. Fujieda, G. Tsuda, 1993, Auris, nasus, larynx.

Long‐Term Follow‐up Results of Electrogustometry and Subjective Taste Disorder After Middle Ear Surgery

H. Saito, T. Ohtsubo, Takehisa Saito, 2001, The Laryngoscope.

Platysma Myocutaneous Flap Including the External Jugular Vein with Special Reference to Neck Dissection

H. Saito, T. Ohtsubo, S. Fujieda, 1998, ORL.

Chemosensitivity of head and neck cancer with the rapid thymidine incorporation assay and its clinical application

T. Ohtsubo, S. Fujieda, H. Saito, 2004, European Archives of Oto-Rhino-Laryngology.

Effect of the p53 gene on synchronization of cells with hydroxyurea and on the cell phase response to hyperthermia in vitro

H. Itoh, H. Matsumoto, S. Hayashi, 2000 .

Endoscopic polypectomy for pacemaker patients.

S. Nagataki, T. Ohtsubo, S. Morita, 1995, Chinese medical journal.

Intraoperative Identification of Regenerated Chorda tympani Nerve and Its Relationship to Recovered Taste Function

T. Ohtsubo, Takehisa Saito, H. Igawa, 2001, ORL.

Mutator Phenotype of MUTYH-null Mouse Embryonic Stem Cells*

K. Sakumi, Y. Nakabeppu, T. Ohtsubo, 2003, Journal of Biological Chemistry.

Incidence of Regeneration of the Chorda Tympani Nerve after Middle Ear Surgery

T. Ohtsubo, Takehisa Saito, H. Igawa, 2002, The Annals of otology, rhinology, and laryngology.

A Case of Cavernous Lymphangioma of the Cheek in an Adult Woman

T. Ohtsubo, M. Tsubokawa, H. Saito, 1993 .

Two Cases of Thyroglossal Duct Cysts in the Thyroid Gland

T. Ohtsubo, S. Fujieda, H. Tsuzuki, 1993 .

Subcutaneous Xanthogranuloma of the Neck; A Case Report.

T. Ohtsubo, H. Tsuzuki, Takehisa Saito, 1998 .

Doxorubicin ototoxicity is induced in mice by combination treatment with cyclosporin A.

T. Ohtsubo, T. Yamamoto, T. Saito, 2001, Acta oto-laryngologica.

Disruption of mdr1a p-glycoprotein gene results in dysfunction of blood–inner ear barrier in mice

T. Ohtsubo, C. Sugimoto, Takehisa Saito, 2000, Brain Research.

Gene Expression Analysis of Human Middle Ear Cholesteatoma Using Complementary DNA Arrays

T. Ohtsubo, S. Fujieda, H. Tsuzuki, 2003, The Laryngoscope.

Induction of Radioresistance by a Nitric Oxide-Mediated Bystander Effect

Ken Ohnishi, Takeo Ohnishi, Hideki Matsumoto, 2001, Radiation research.

Expression of p-glycoprotein is associated with that of multidrug resistance protein 1 (MRP1) in the vestibular labyrinth and endolymphatic sac of the guinea pig

Zhi Jian Zhang, Hitoshi Saito, Ichiro Noda, 2001, Neuroscience Letters.

The interactive effect of heat treatment combined with cisplatin (CDDP) or mitomycin C (MMC) on human gingival carcinoma cells

T. Ohtsubo, E. Kano, H. Saito, 1993 .

Enhancement of cisplatin sensitivity and platinum uptake by 40 °C hyperthermia in resistant cells

Sachiko Hayashi, Hideki Matsumoto, H. Matsumoto, 1997 .

In vitro effects of hyperthermia combined with cisplatin or peplomycin on the human maxillary carcinoma cell line IMC-2.

H. Matsumoto, S. Hayashi, T. Ohtsubo, 1997, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

Postoperative Cholesterol Cysts of the Mastoid

T. Ohtsubo, Mizue Seki, Takehisa Satto, 1996, The Annals of otology, rhinology, and laryngology.

A Case of Small Cell Carcinoma in the Nasal Cavity

T. Ohtsubo, Y. Imamura, Y. Manabe, 1993 .

[Efficacy of middle ear surgery for patients with hearing aids and middle ear disease].

T. Ohtsubo, T. Yamamoto, T. Saito, 1999, Nihon Jibiinkoka Gakkai kaiho.

Implications of Endoscopic Endonasal Surgery for the Treatment of Postoperative Maxillary Mucoceles

T. Ohtsubo, Takehisa Saito, I. Noda, 1999, ORL.

Chemotherapy for head and neck malignant tumors in the elderly.

T. Ohtsubo, S. Fujieda, H. Saito, 1989 .

[Treatment strategy for T4N1 thyroid papillary carcinoma based upon our clinical experience].

T. Ohtsubo, S. Fujieda, H. Tsuzuki, 2003, Nihon Jibiinkoka Gakkai kaiho.