T. Etrych

发表

HPMA copolymers containing doxorubicin bound by a proteolytically or hydrolytically cleavable bond: comparison of biological properties in vitro.

K. Ulbrich, V. Šubr, M. Kovar, 2004, Journal of controlled release : official journal of the Controlled Release Society.

Polymer‐coated polyethylenimine/DNA complexes designed for triggered activation by intracellular reduction

K. Ulbrich, T. Etrych, L. Seymour, 2004, The journal of gene medicine.

Characterisation of the binding interaction between poly(L‐lysine) and DNA using the fluorescamine assay in the preparation of non‐viral gene delivery vectors

K. Ulbrich, T. Etrych, Martin L Read, 1999, FEBS letters.

Micelle-forming HPMA copolymer conjugates of ritonavir bound via a pH-sensitive spacer with improved cellular uptake designed for enhanced tumor accumulation.

V. Šubr, T. Etrych, S. Filippov, 2016, Journal of materials chemistry. B.

Polymer Cancerostatics Containing Cell-Penetrating Peptides: Internalization Efficacy Depends on Peptide Type and Spacer Length

T. Etrych, O. Janoušková, D. Machová, 2020, Pharmaceutics.

Fluorescence Imaging as a Tool in Preclinical Evaluation of Polymer-Based Nano-DDS Systems Intended for Cancer Treatment

T. Etrych, O. Janoušková, P. Chytil, 2019, Pharmaceutics.

Nanotherapeutics with suitable properties for advanced anticancer therapy based on HPMA copolymer‐bound ritonavir via pH‐sensitive spacers

T. Etrych, O. Janoušková, D. Machová, 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Polymer Nanomedicines with Ph-Sensitive Release of Dexamethasone for the Localized Treatment of Inflammation

D. Scherman, T. Etrych, G. Renault, 2020, Pharmaceutics.

Polymer-drug conjugates in inflammation treatment.

T. Etrych, E. Koziolová, K. Venclíková, 2018, Physiological research.

Interaction of N-(2-Hydroxypropyl)methacrylamide Copolymer-Doxorubicin Conjugates with Human Liver Microsomal Cytochromes P450: Comparison with Free Doxorubicin

K. Ulbrich, P. Anzenbacher, T. Etrych, 2011, Drug Metabolism and Disposition.

High-molecular-weight HPMA-based polymer drug carriers for delivery to tumor.

T. Etrych, L. Kostka, 2016, Physiological research.

HPMA copolymer-doxorubicin conjugates: The effects of molecular weight and architecture on biodistribution and in vivo activity.

K. Ulbrich, V. Šubr, T. Etrych, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Intrinsically active nanobody-modified polymeric micelles for tumor-targeted combination therapy.

K. Ulbrich, W. Hennink, T. Etrych, 2013, Biomaterials.

New HPMA copolymers containing doxorubicin bound via pH-sensitive linkage: synthesis and preliminary in vitro and in vivo biological properties.

K. Ulbrich, T. Etrych, M. Jelínková, 2001, Journal of controlled release : official journal of the Controlled Release Society.

Combination chemotherapy using core-shell nanoparticles through the self-assembly of HPMA-based copolymers and degradable polyester.

K. Ulbrich, P. Štěpánek, T. Etrych, 2013, Journal of controlled release : official journal of the Controlled Release Society.

Comparison between linear and star-like HPMA conjugated pirarubicin (THP) in pharmacokinetics and antitumor activity in tumor bearing mice.

K. Ulbrich, H. Maeda, T. Etrych, 2015, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Targeted Polymer-Based Probes for Fluorescence Guided Visualization and Potential Surgery of EGFR-Positive Head-and-Neck Tumors

T. Etrych, J. Bouček, D. Větvička, 2020, Pharmaceutics.

HPMA copolymer-antibody constructs in neoplastic treatment: an overview of therapeutics, targeted diagnostics, and drug-free systems.

T. Etrych, Eva Randárová, Júlia Kudláčová, 2020, Journal of controlled release : official journal of the Controlled Release Society.

Doxorubicin release is not a prerequisite for the in vitro cytotoxicity of HPMA-based pharmaceuticals: in vitro effect of extra drug-free GlyPheLeuGly sequences.

K. Ulbrich, V. Šubr, T. Etrych, 2008, Journal of controlled release : official journal of the Controlled Release Society.

PCL-PEG graft copolymers with tunable amphiphilicity as efficient drug delivery systems.

T. Etrych, B. Nottelet, J. Coudane, 2016, Journal of materials chemistry. B.

High-molecular weight star conjugates containing docetaxel with high anti-tumor activity and low systemic toxicity in vivo

K. Ulbrich, M. Kovar, T. Etrych, 2015 .

Biodegradable star HPMA polymer-drug conjugates: Biodegradability, distribution and anti-tumor efficacy.

K. Ulbrich, L. Kovář, T. Etrych, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Novel star HPMA-based polymer conjugates for passive targeting to solid tumors

K. Ulbrich, T. Etrych, B. Říhová, 2011, Journal of drug targeting.

N-(2-Hydroxypropyl)methacrylamide-Based Polymer Conjugates with pH-Controlled Activation of Doxorubicin. I. New Synthesis, Physicochemical Characterization and Preliminary Biological Evaluation

K. Ulbrich, T. Etrych, T. Mrkvan, 2008 .

Overcoming resistance to rituximab in relapsed non-Hodgkin lymphomas by antibody-polymer drug conjugates actively targeted by anti-CD38 daratumumab.

T. Etrych, K. Helman, O. Janoušková, 2020, Journal of controlled release : official journal of the Controlled Release Society.

Interaction of spin-labeled HPMA-based nanoparticles with human blood plasma proteins - the introduction of protein-corona-free polymer nanomedicine.

D. Weitz, I. Raška, T. Etrych, 2018, Nanoscale.

Inhibitor-Decorated Polymer Conjugates Targeting Fibroblast Activation Protein.

V. Šubr, J. Konvalinka, T. Etrych, 2017, Journal of medicinal chemistry.

Inhibitor-GCPII Interaction: Selective and Robust System for Targeting Cancer Cells with Structurally Diverse Nanoparticles.

V. Šubr, J. Konvalinka, T. Etrych, 2018, Molecular pharmaceutics.

Molecular Mechanisms of the Interactions of N-(2-Hydroxypropyl)methacrylamide Copolymers Designed for Cancer Therapy with Blood Plasma Proteins

D. Svergun, T. Etrych, A. Gruzinov, 2020, Pharmaceutics.

Superior Penetration and Cytotoxicity of HPMA Copolymer Conjugates of Pirarubicin in Tumor Cell Spheroid.

H. Maeda, T. Etrych, M. Haratake, 2019, Molecular pharmaceutics.

Drug carriers with star polymer structures.

T. Etrych, L. Kotrchová, L. Kostka, 2018, Physiological research.

Graft copolymers with tunable amphiphilicity tailored for efficient dual drug delivery via encapsulation and pH-sensitive drug conjugation

T. Etrych, B. Nottelet, Eva Randárová, 2020 .

Comparison of the pharmacological and biological properties of HPMA copolymer‐pirarubicin conjugates: A single‐chain copolymer conjugate and its biodegradable tandem‐diblock copolymer conjugate

K. Ulbrich, H. Maeda, T. Etrych, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Improved Tumor-Specific Drug Accumulation by Polymer Therapeutics with pH-Sensitive Drug Release Overcomes Chemotherapy Resistance

T. Etrych, T. Mueller, K. Mäder, 2016, Molecular Cancer Therapeutics.

Nanotherapeutics shielded with a pH responsive polymeric layer.

K. Ulbrich, V. Šubr, T. Etrych, 2015, Physiological research.

Preclinical Evaluation of Linear HPMA-Doxorubicin Conjugates with pH-Sensitive Drug Release: Efficacy, Safety, and Immunomodulating Activity in Murine Model

K. Ulbrich, L. Kovář, T. Etrych, 2009, Pharmaceutical Research.

HPMA-Based Copolymers Carrying STAT3 Inhibitor Cucurbitacin-D as Stimulus-Sensitive Nanomedicines for Oncotherapy

T. Etrych, B. Říhová, M. Šírová, 2021, Pharmaceutics.

Polymeric nanogels as drug delivery systems.

T. Etrych, J. Kousalová, 2018, Physiological research.

Targeted Drug Delivery by Radiation-Induced Tumor Vascular Modulation

O. Tillement, R. Kumar, R. Berbeco, 2018, bioRxiv.

Star structure of antibody-targeted HPMA copolymer-bound doxorubicin: a novel type of polymeric conjugate for targeted drug delivery with potent antitumor effect.

K. Ulbrich, T. Etrych, B. Říhová, 2002, Bioconjugate chemistry.

Cytostatic and immunomobilizing activities of polymer-bound drugs: experimental and first clinical data.

K. Ulbrich, V. Šubr, T. Etrych, 2003, Journal of controlled release : official journal of the Controlled Release Society.

Micelle-Forming Block Copolymers Tailored for Inhibition of P-gp-Mediated Multidrug Resistance: Structure to Activity Relationship

T. Etrych, J. Bouček, J. Betka, 2019, Pharmaceutics.

HPMA-hydrogels containing cytostatic drugs. Kinetics of the drug release and in vivo efficacy.

K. Ulbrich, T. Etrych, B. Říhová, 2002, Journal of controlled release : official journal of the Controlled Release Society.

Dual fluorescent HPMA copolymers for passive tumor targeting with pH-sensitive drug release II: impact of release rate on biodistribution.

K. Ulbrich, T. Etrych, T. Mueller, 2013, Journal of controlled release : official journal of the Controlled Release Society.

Dual fluorescent HPMA copolymers for passive tumor targeting with pH-sensitive drug release: synthesis and characterization of distribution and tumor accumulation in mice by noninvasive multispectral optical imaging.

K. Ulbrich, T. Etrych, T. Mueller, 2012, Biomacromolecules.

Overcoming multidrug resistance via simultaneous delivery of cytostatic drug and P-glycoprotein inhibitor to cancer cells by HPMA copolymer conjugate.

V. Šubr, T. Etrych, B. Říhová, 2017, Biomaterials.

Oligopeptide-targeted polymer nanoprobes for fluorescence-guided endoscopic surgery

T. Etrych, J. Bouček, D. Větvička, 2019, Multifunctional Materials.

Polymer Cancerostatics Targeted by Recombinant Antibody Fragments to GD2-Positive Tumor Cells.

V. Král, T. Etrych, S. Filippov, 2018, Biomacromolecules.

The pH-dependent and enzymatic release of cytarabine from hydrophilic polymer conjugates.

T. Etrych, O. Janoušková, R. Pola, 2016, Physiological research.

Synergistic action of doxorubicin bound to the polymeric carrier based on N-(2-hydroxypropyl)methacrylamide copolymers through an amide or hydrazone bond.

K. Ulbrich, L. Kovář, T. Etrych, 2010, Molecular pharmaceutics.

HPMA based macromolecular therapeutics: Internalization, intracellular pathway and cell death depend on the character of covalent bond between the drug and the peptidic spacer and also on spacer composition

K. Ulbrich, V. Šubr, T. Etrych, 2006, Journal of drug targeting.

Hydroxybisphosphonate‐containing polymeric drug‐delivery systems designed for targeting into bone tissue

K. Ulbrich, T. Etrych, J. Kučka, 2006 .

Simultaneous Delivery of Doxorubicin and Protease Inhibitor Derivative to Solid Tumors via Star-Shaped Polymer Nanomedicines Overcomes P-gp- and STAT3-Mediated Chemoresistance.

V. Šubr, T. Etrych, B. Říhová, 2022, Biomacromolecules.

Pronounced Cellular Uptake of Pirarubicin versus That of Other Anthracyclines: Comparison of HPMA Copolymer Conjugates of Pirarubicin and Doxorubicin.

K. Ulbrich, H. Maeda, T. Etrych, 2016, Molecular pharmaceutics.

HPMA Copolymer-Conjugated Pirarubicin in Multimodal Treatment of a Patient with Stage IV Prostate Cancer and Extensive Lung and Bone Metastases

K. Ulbrich, H. Maeda, T. Etrych, 2016, Targeted Oncology.

Augmentation of EPR Effect and Efficacy of Anticancer Nanomedicine by Carbon Monoxide Generating Agents

K. Ulbrich, V. Šubr, H. Maeda, 2019, Pharmaceutics.

Two step mechanisms of tumor selective delivery of N-(2-hydroxypropyl)methacrylamide copolymer conjugated with pirarubicin via an acid-cleavable linkage.

K. Ulbrich, H. Maeda, T. Etrych, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Overcoming immunoescape mechanisms of BCL1 leukemia and induction of CD8+ T-cell-mediated BCL1-specific resistance in mice cured by targeted polymer-bound doxorubicin.

K. Ulbrich, L. Kovář, T. Etrych, 2008, Cancer research.

Doxorubicin Resistance in Mice Cured by Targeted Polymer-Bound Mediated BCL 1-Specific − T-Cell + and Induction of CD 8 Overcoming Immunoescape Mechanisms of BCL 1 Leukemia

K. Ulbrich, L. Kovář, T. Etrych, 2008 .

Structural Design and Synthesis of Polymer Prodrugs

T. Etrych, P. Chytil, L. Kostka, 2017 .

Iterative Photoinduced Chain Functionalization as a Generic Platform for Advanced Polymeric Drug Delivery Systems.

T. Etrych, B. Nottelet, J. Coudane, 2018, Macromolecular rapid communications.

Nanomedicines for inflammatory arthritis: head-to-head comparison of glucocorticoid-containing polymers, micelles, and liposomes.

K. Ulbrich, F. Kiessling, W. Hennink, 2014, ACS nano.

Supplementary Text and Figures to In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity

Michael Y. Gerner, Kylie M. Quinn, Janine K. Tom, 2015 .

Synergistic effect of EMF–BEMER-type pulsed weak electromagnetic field and HPMA-bound doxorubicin on mouse EL4 T-cell lymphoma

K. Ulbrich, T. Etrych, B. Říhová, 2011, Journal of drug targeting.

Singlet Oxygen In Vivo: It Is All about Intensity

V. Šubr, S. Hackbarth, T. Etrych, 2022, Journal of personalized medicine.

Overcoming multidrug resistance in Dox-resistant neuroblastoma cell lines via treatment with HPMA copolymer conjugates containing anthracyclines and P-gp inhibitors.

K. Ulbrich, V. Šubr, T. Etrych, 2016, Journal of controlled release : official journal of the Controlled Release Society.

The structure of polymer carriers controls the efficacy of the experimental combination treatment of tumors with HPMA copolymer conjugates carrying doxorubicin and docetaxel

T. Etrych, B. Říhová, M. Šírová, 2017, Journal of controlled release : official journal of the Controlled Release Society.

Tumor Stimulus-Responsive Biodegradable Diblock Copolymer Conjugates as Efficient Anti-Cancer Nanomedicines

V. Šubr, T. Etrych, Jun Fang, 2022, Journal of personalized medicine.

Binding of HSA to Macromolecular pHPMA Based Nanoparticles for Drug Delivery: An Investigation Using Fluorescence Methods.

G. Winter, T. Etrych, S. Filippov, 2018, Langmuir.

The transmission and toxicity of polymer-bound doxorubicin-containing exosomes derived from human adenocarcinoma cells.

T. Etrych, O. Janoušková, Aneta Dydowiczová, 2022, Nanomedicine.

Core-crosslinked polymeric micelles with controlled release of covalently entrapped doxorubicin.

K. Ulbrich, C. van Nostrum, W. Hennink, 2010, Biomaterials.

HPMA-based polymer conjugates with drug combination.

K. Ulbrich, T. Etrych, H. Krakovicová, 2009, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Synthesis and Properties of Poly[N-(2-Hydroxypropyl) Methacrylamide] Conjugates of Superoxide Dismutase

K. Ulbrich, T. Kondo, T. Etrych, 2002 .

Metastatic spread inhibition of cancer cells through stimuli-sensitive HPMA copolymer-bound actinonin nanomedicines.

V. Šubr, T. Etrych, M. Šírová, 2022, Nanomedicine : nanotechnology, biology, and medicine.

Star Polymer-Drug Conjugates with pH-Controlled Drug Release and Carrier Degradation

T. Etrych, L. Kotrchová, L. Kostka, 2017 .

Synthesis and Properties of Star HPMA Copolymer Nanocarriers Synthesised by RAFT Polymerisation Designed for Selective Anticancer Drug Delivery and Imaging.

K. Ulbrich, T. Etrych, O. Janoušková, 2015, Macromolecular bioscience.

New HPMA copolymer-based drug carriers with covalently bound hydrophobic substituents for solid tumour targeting.

K. Ulbrich, T. Etrych, T. Mrkvan, 2008, Journal of controlled release : official journal of the Controlled Release Society.

Effect of physicochemical modification on the biodistribution and tumor accumulation of HPMA copolymers.

K. Ulbrich, V. Šubr, T. Etrych, 2005, Journal of controlled release : official journal of the Controlled Release Society.

Hydrolytically degradable polymer micelles for drug delivery: a SAXS/SANS kinetic study.

K. Ulbrich, D. Svergun, P. Štěpánek, 2013, Biomacromolecules.

Highly effective anti-tumor nanomedicines based on HPMA copolymer conjugates with pirarubicin prepared by controlled RAFT polymerization.

T. Etrych, Jun Fang, Hideaki Nakamura, 2020, Acta biomaterialia.

HPMA-based star polymer biomaterials with tuneable structure and biodegradability tailored for advanced drug delivery to solid tumours.

V. Šubr, W. Cai, T. Etrych, 2019, Biomaterials.

Synthesis of water-soluble star polymers based on cyclodextrins.

T. Etrych, L. Kotrchová, 2018, Physiological research.

Polymer nitric oxide donors potentiate the treatment of experimental solid tumours by increasing drug accumulation in the tumour tissue

T. Etrych, B. Říhová, O. Sedláček, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Dual fluorescent N-(2-hydroxypropyl) methacrylamide-based conjugates for passive tumor targeting with reduction-sensitive drug release: Proof of the concept, tumor accumulation, and biodistribution

T. Etrych, T. Mueller, K. Mäder, 2016 .

Anti-Lymphoma Efficacy Comparison of Anti-CD20 Monoclonal Antibody-Targeted and Non-Targeted Star-Shaped Polymer-Prodrug Conjugates

T. Etrych, O. Janoušková, J. Strohalm, 2015, Molecules.

Thermoresponsive Polymer Micelles as Potential Nanosized Cancerostatics.

K. Ulbrich, T. Etrych, S. Filippov, 2015, Biomacromolecules.

Nanotherapeutics with anthracyclines: methods of determination and quantification of anthracyclines in biological samples.

T. Etrych, O. Janoušková, E. Koziolová, 2015, Physiological research.

Polymer conjugates of doxorubicin bound through an amide and hydrazone bond: Impact of the carrier structure onto synergistic action in the treatment of solid tumours.

K. Ulbrich, V. Šubr, T. Etrych, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Polymer carriers for anticancer drugs targeted to EGF receptor.

K. Ulbrich, L. Kovář, T. Etrych, 2012, Macromolecular bioscience.

Hydrolytically Degradable Polymer Micelles for Anticancer Drug Delivery to Solid Tumors

K. Ulbrich, T. Etrych, P. Chytil, 2012 .

Use of synthetic vectors for neutralising antibody resistant delivery of replicating adenovirus DNA

K. Ulbrich, T. Etrych, S. Briggs, 2006, Gene Therapy.

Synthesis of HPMA Copolymers Containing Doxorubicin Bound via a Hydrazone Linkage. Effect of Spacer on Drug Release and in vitro Cytotoxicity

K. Ulbrich, T. Etrych, B. Říhová, 2002 .

The development of a high-affinity conformation-sensitive antibody mimetic using a biocompatible copolymer carrier (iBody)

V. Šubr, J. Konvalinka, T. Etrych, 2021, The Journal of biological chemistry.

Tailoring the physicochemical properties of core-crosslinked polymeric micelles for pharmaceutical applications.

F. Kiessling, W. Hennink, T. Etrych, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Polymer-Based Drug-Free Therapeutics for Anticancer, Anti-Inflammatory, and Antibacterial Treatment.

T. Etrych, M. Pechar, P. Chytil, 2021, Macromolecular bioscience.

Polymer nanomedicines based on micelle-forming amphiphilic or water-soluble polymer-doxorubicin conjugates: Comparative study of in vitro and in vivo properties related to the polymer carrier structure, composition, and hydrodynamic properties.

T. Etrych, B. Říhová, O. Janoušková, 2020, Journal of controlled release : official journal of the Controlled Release Society.

High-affinity HPMA copolymers with tailored N-acetyllactosamine presentation discriminate between galectins.

V. Křen, T. Etrych, L. Elling, 2020, Biomacromolecules.

HPMA copolymer-based polymer conjugates for the delivery and controlled release of retinoids.

T. Etrych, M. Šírová, O. Lidický, 2016, Physiological research.

Macromolecular HPMA-based nanoparticles with cholesterol for solid-tumor targeting: detailed study of the inner structure of a highly efficient drug delivery system.

K. Ulbrich, D. Svergun, P. Štěpánek, 2012, Biomacromolecules.

Polymeric anticancer drugs with pH-controlled activation.

K. Ulbrich, T. Etrych, B. Říhová, 2004, International journal of pharmaceutics.

HPMA copolymer-bound doxorubicin targeted to tumor-specific antigen of BCL1 mouse B cell leukemia.

K. Ulbrich, T. Etrych, T. Mrkvan, 2003, Journal of controlled release : official journal of the Controlled Release Society.

Conjugates of doxorubicin with graft HPMA copolymers for passive tumor targeting.

K. Ulbrich, T. Etrych, T. Mrkvan, 2008, Journal of controlled release : official journal of the Controlled Release Society.

HPMA copolymers with pH-controlled release of doxorubicin: in vitro cytotoxicity and in vivo antitumor activity.

K. Ulbrich, T. Etrych, B. Říhová, 2003, Journal of controlled release : official journal of the Controlled Release Society.

Singlet oxygen phosphorescence detection in vivo identifies PDT-induced anoxia in solid tumors

V. Šubr, S. Hackbarth, B. Röder, 2019, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

Glycopolymers for Efficient Inhibition of Galectin-3: In Vitro Proof of Efficacy Using Suppression of T Lymphocyte Apoptosis and Tumor Cell Migration.

V. Křen, T. Etrych, L. Bumba, 2020, Biomacromolecules.

Self-assembly of biodegradable copolyester and reactive HPMA-based polymers into nanoparticles as an alternative stealth drug delivery system

K. Ulbrich, P. Štěpánek, J. Putaux, 2012 .

HPMA copolymer conjugates of paclitaxel and docetaxel with pH-controlled drug release.

K. Ulbrich, T. Etrych, B. Říhová, 2010, Molecular pharmaceutics.

Biocompatible glyconanomaterials based on HPMA-copolymer for specific targeting of galectin-3

V. Křen, T. Etrych, L. Bumba, 2018, Journal of Nanobiotechnology.

Doxorubicin attached to HPMA copolymer via amide bond modifies the glycosylation pattern of EL4 cells

K. Ulbrich, V. Šubr, L. Kovář, 2010, Tumor Biology.

Targeted Drug Delivery and Theranostic Strategies in Malignant Lymphomas

T. Etrych, P. Klener, L. Lambert, 2022, Cancers.

Biological Therapy of Hematologic Malignancies: Toward a Chemotherapy- free Era.

T. Etrych, P. Klener, 2019, Current medicinal chemistry.

HPMA-Based Polymer Conjugates for Repurposed Drug Mebendazole and Other Imidazole-Based Therapeutics

T. Etrych, M. Studenovský, L. Kostka, 2021, Polymers.

Effect of cellular and microenvironmental multidrug resistance on tumor-targeted drug delivery in triple-negative breast cancer.

F. Kiessling, T. Etrych, R. Weiskirchen, 2023, Journal of controlled release : official journal of the Controlled Release Society.

Fluorescence optical imaging in anticancer drug delivery.

T. Etrych, T. Mueller, O. Janoušková, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Impact of Polymer-TLR-7/8 Agonist (Adjuvant) Morphology on the Potency and Mechanism of CD8 T Cell Induction.

Michael Y. Gerner, K. Ulbrich, A. Wang, 2019, Biomacromolecules.

Augmentation of the Enhanced Permeability and Retention Effect with Nitric Oxide–Generating Agents Improves the Therapeutic Effects of Nanomedicines

K. Ulbrich, V. Šubr, H. Maeda, 2018, Molecular Cancer Therapeutics.

Dye labeling for optical imaging biases drug carriers' biodistribution and tumor uptake.

F. Kiessling, T. Etrych, T. Lammers, 2023, Nanomedicine : nanotechnology, biology, and medicine.

In vivo characterization of the physicochemical properties of TLR agonist delivery that enhance vaccine immunogenicity

Michael Y. Gerner, Kylie M. Quinn, Janine K. Tom, 2015, Nature Biotechnology.

HPMA Copolymer-Drug Conjugates with Controlled Tumor-Specific Drug Release.

K. Ulbrich, T. Etrych, E. Koziolová, 2018, Macromolecular bioscience.

HPMA copolymer conjugates with reduced anti-CD20 antibody for cell-specific drug targeting. I. Synthesis and in vitro evaluation of binding efficacy and cytostatic activity.

K. Ulbrich, L. Kovář, T. Etrych, 2009, Journal of controlled release : official journal of the Controlled Release Society.

Star-shaped immunoglobulin-containing HPMA-based conjugates with doxorubicin for cancer therapy.

K. Ulbrich, T. Etrych, T. Mrkvan, 2007, Journal of controlled release : official journal of the Controlled Release Society.

Properties of HPMA copolymer-doxorubicin conjugates with pH-controlled activation: effect of polymer chain modification.

K. Ulbrich, T. Etrych, T. Mrkvan, 2006, Journal of controlled release : official journal of the Controlled Release Society.

Antibody-targeted Polymer–doxorubicin Conjugates with pH-controlled Activation

K. Ulbrich, T. Etrych, B. Říhová, 2004, Journal of drug targeting.

Cytarabine nanotherapeutics with increased stability and enhanced lymphoma uptake for tailored highly effective therapy of mantle cell lymphoma.

T. Etrych, K. Helman, L. Šefc, 2020, Acta biomaterialia.

Polyelectrolyte complex formation and stability when mixing polyanions and polycations in salted media: a model study related to the case of body fluids.

T. Etrych, M. Vert, L. Leclercq, 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Release of Polyanions from Polyelectrolyte Complexes by Selective Degradation of the Polycation

T. Etrych, M. Vert, M. Boustta, 2006 .

Cell-penetrating peptides: a useful tool for the delivery of various cargoes into cells.

T. Etrych, O. Janoušková, D. Machová, 2018, Physiological research.

Author Correction: Selective Priming of Tumor Blood Vessels by Radiation Therapy Enhances Nanodrug Delivery

O. Tillement, R. Kumar, R. Berbeco, 2020, Scientific Reports.

HPMA Copolymer-Based Nanomedicines in Controlled Drug Delivery

T. Etrych, P. Chytil, L. Kostka, 2021, Journal of personalized medicine.

ReviewHPMA Copolymer-Based Nanomedicines in Controlled Drug DeliveryPetr Chytil

T. Etrych, P. Chytil, L. Kostka, 2021 .

Retraction Note: Selective Priming of Tumor Blood Vessels by Radiation Therapy Enhances Nanodrug Delivery

O. Tillement, R. Berbeco, T. Etrych, 2022, Scientific Reports.

Biological evaluation of polymeric micelles with covalently bound doxorubicin.

K. Ulbrich, L. Kovář, T. Etrych, 2009, Bioconjugate chemistry.

Glycopolymers Decorated with 3-O-Substituted Thiodigalactosides as Potent Multivalent Inhibitors of Galectin-3.

V. Křen, T. Etrych, L. Bumba, 2022, Journal of medicinal chemistry.

N-(2-Hydroxypropyl)methacrylamide-based polymer conjugates with pH-controlled activation of doxorubicin for cell-specific or passive tumour targeting. Synthesis by RAFT polymerisation and physicochemical characterisation.

K. Ulbrich, V. Šubr, T. Etrych, 2010, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Effective doxorubicin‐based nano‐therapeutics for simultaneous malignant lymphoma treatment and lymphoma growth imaging

T. Etrych, L. Šefc, V. Kolářová, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Differences in the intracellular fate of free and polymer-bound doxorubicin.

K. Ulbrich, V. Šubr, T. Etrych, 2002, Journal of controlled release : official journal of the Controlled Release Society.

N‐(2‐hydroxypropyl)methacrylamide polymer conjugated pyropheophorbide‐a, a promising tumor‐targeted theranostic probe for photodynamic therapy and imaging

K. Ulbrich, V. Šubr, S. Hackbarth, 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

HPMA copolymer conjugate with pirarubicin: In vitro and ex vivo stability and drug release study.

K. Ulbrich, H. Maeda, T. Etrych, 2018, International journal of pharmaceutics.

Size-switchable polymer-based nanomedicines in the advanced therapy of rheumatoid arthritis.

D. Scherman, T. Etrych, M. Bartoš, 2022, Journal of controlled release : official journal of the Controlled Release Society.

N-(2-Hydroxypropyl)methacrylamide-Based Linear, Diblock, and Starlike Polymer Drug Carriers: Advanced Process for Their Simple Production.

V. Šubr, T. Etrych, B. Nottelet, 2018, Biomacromolecules.

Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling.

V. Šubr, T. Etrych, B. Říhová, 2021, Journal of controlled release : official journal of the Controlled Release Society.

HPMA Copolymer Mebendazole Conjugate Allows Systemic Administration and Possesses Antitumour Activity In Vivo

T. Etrych, M. Studenovský, L. Kostka, 2022, Pharmaceutics.

Influence of molar mass, dispersity, and type and location of hydrophobic side chain moieties on the critical micellar concentration and stability of amphiphilic HPMA-based polymer drug carriers

T. Etrych, S. Filippov, C. Papadakis, 2017, Colloid and Polymer Science.

Octahedral Molybdenum Cluster-Based Nanomaterials for Potential Photodynamic Therapy

T. Etrych, N. Kotov, K. Lang, 2022, Nanomaterials.

Overcoming multidrug resistance using folate receptor-targeted and pH-responsive polymeric nanogels containing covalently entrapped doxorubicin.

K. Ulbrich, W. Hennink, T. Etrych, 2017, Nanoscale.

Chemotherapy based on HPMA copolymer conjugates with pH-controlled release of doxorubicin triggers anti-tumor immunity.

K. Ulbrich, T. Etrych, T. Mrkvan, 2005, Journal of controlled release : official journal of the Controlled Release Society.

A tumor-targeted polymer theranostics platform for positron emission tomography and fluorescence imaging.

W. Cai, T. Etrych, T. Barnhart, 2017, Nanoscale.

HPMA-hydrogels result in prolonged delivery of anticancer drugs and are a promising tool for the treatment of sensitive and multidrug resistant leukaemia.

K. Ulbrich, T. Etrych, B. Říhová, 2002, European journal of cancer.

Intended and Unintended Targeting of Polymeric Nanocarriers: The Case of Modified Poly(glycerol adipate) Nanoparticles.

T. Etrych, J. Kressler, T. Mueller, 2018, Macromolecular bioscience.

Glycan-decorated HPMA copolymers as high-affinity lectin ligands

V. Křen, T. Etrych, L. Bumba, 2017 .

Noninvasive optical imaging of nanomedicine biodistribution.

Fabian Kiessling, Gert Storm, Felix Gremse, 2013, ACS nano.

The structure-dependent toxicity, pharmacokinetics and anti-tumour activity of HPMA copolymer conjugates in the treatment of solid tumours and leukaemia.

K. Ulbrich, T. Etrych, B. Říhová, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Structure-to-Efficacy Relationship of HPMA-Based Nanomedicines: The Tumor Spheroid Penetration Study

T. Etrych, O. Janoušková, Jun Fang, 2020, Pharmaceutics.

RETRACTED ARTICLE: Selective Priming of Tumor Blood Vessels by Radiation Therapy Enhances Nanodrug Delivery

O. Tillement, R. Kumar, R. Berbeco, 2019, Scientific Reports.

Acid-labile pHPMA modification of four-arm oligoaminoamide pDNA polyplexes balances shielding and gene transfer activity in vitro and in vivo.

T. Etrych, E. Wagner, Ulrich Lächelt, 2016, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Overcoming cellular multidrug resistance using classical nanomedicine formulations.

K. Ulbrich, F. Kiessling, T. Etrych, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

HPMA copolymer-bound doxorubicin induces immunogenic tumor cell death.

K. Ulbrich, L. Kovář, T. Etrych, 2013, Current medicinal chemistry.

Cytotoxic and Immunomodulatory Activites of Polymer-Bound Drugs

K. Ulbrich, V. Šubr, T. Etrych, 2004 .

Polymer donors of nitric oxide improve the treatment of experimental solid tumours with nanosized polymer therapeutics

T. Etrych, B. Říhová, M. Šírová, 2017, Journal of drug targeting.

Evaluation of linear versus star-like polymer anti-cancer nanomedicines in mouse models.

W. Cai, T. Etrych, J. Engle, 2022, Journal of controlled release : official journal of the Controlled Release Society.

Synergistic effect of HPMA copolymer-bound doxorubicin and dexamethasone in vivo on mouse lymphomas

K. Ulbrich, T. Etrych, B. Říhová, 2011 .

The comparison of in vivo properties of water-soluble HPMA-based polymer conjugates with doxorubicin prepared by controlled RAFT or free radical polymerization.

K. Ulbrich, T. Etrych, B. Říhová, 2015, Physiological research.

Coating Persistent Luminescence Nanoparticles With Hydrophilic Polymers for in vivo Imaging

D. Scherman, T. Etrych, C. Richard, 2020, Frontiers in Chemistry.

Biodegradable star HPMA polymer conjugates of doxorubicin for passive tumor targeting.

K. Ulbrich, T. Etrych, J. Strohalm, 2011, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Starlike vs. Classic Macromolecular Prodrugs: Two Different Antibody-Targeted HPMA Copolymers of Doxorubicin Studied in Vitro and in Vivo as Potential Anticancer Drugs

Markéta Jelínková, K. Ulbrich, T. Etrych, 2003, Pharmaceutical Research.

Doxorubicin bound to a HPMA copolymer carrier through hydrazone bond is effective also in a cancer cell line with a limited content of lysosomes.

K. Ulbrich, T. Etrych, B. Říhová, 2001, Journal of controlled release : official journal of the Controlled Release Society.

A Novel Approach to Increase the Stability of Liposomal Containers via In Prep Coating by Poly[N -(2-Hydroxypropyl)Methacrylamide] with Covalently Attached Cholesterol Groups

K. Ulbrich, T. Etrych, L. Kováčik, 2018 .

HPMA copolymer conjugates of DOX and mitomycin C for combination therapy: physicochemical characterization, cytotoxic effects, combination index analysis, and anti-tumor efficacy.

K. Ulbrich, T. Etrych, B. Říhová, 2013, Macromolecular bioscience.

Polymer-Antimicrobial Peptide Constructs with Tailored Drug-Release Behavior

T. Etrych, B. Vokatá, P. Ulbrich, 2023, Pharmaceutics.

Polymer nanomedicines with enzymatically triggered activation: A comparative study of in vitro and in vivo anti-cancer efficacy related to the spacer structure.

T. Etrych, Jun Fang, Aneta Dydowiczová, 2022, Nanomedicine : nanotechnology, biology, and medicine.