H. Pelicano

发表

Interaction of p53 and DNA-PK in response to nucleoside analogues: potential role as a sensor complex for DNA damage.

L. Feng, W. Plunkett, G. Achanta, 2001, Cancer research.

Excision of β-L- and β-D-Nucleotide Analogs From DNA by p53 Protein

Yung-chi Cheng, H. Pelicano, M. Kukhanova, 2000 .

The Circadian Gene Period2 Plays an Important Role in Tumor Suppression and DNA Damage Response In Vivo

Peng Huang, Jinsong Liu, Jinsong Liu, 2002, Cell.

Synergistic effect of targeting mTOR by rapamycin and depleting ATP by inhibition of glycolysis in lymphoma and leukemia cells

H. Pelicano, P. Huang, Peng Huang, 2005, Leukemia.

Long non-coding RNA XIST regulates gastric cancer progression by acting as a molecular sponge of miR-101 to modulate EZH2 expression

Fenghua Wang, Yu-hong Li, H. Pelicano, 2016, Journal of Experimental & Clinical Cancer Research.

ROS stress in cancer cells and therapeutic implications.

Peng Huang, Dennis Carney, H. Pelicano, 2004, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism

Peng Huang, Li Feng, Ryohei Sasaki, 2006, The Journal of cell biology.

Antibody-induced nonapoptotic cell death in human lymphoma and leukemia cells is mediated through a novel reactive oxygen species-dependent pathway.

H. Pelicano, T. Illidge, M. Cragg, 2012, Blood.

Glycolysis inhibition for anticancer treatment

H. Pelicano, P. Huang, D. Martin, 2006, Oncogene.

Inhibition of Mitochondrial Respiration

W. Plunkett, H. Pelicano, Peng Huang, 2003, Journal of Biological Chemistry.

OSW-1: a natural compound with potent anticancer activity and a novel mechanism of action.

Z. Estrov, D. Harris, Jinsong Liu, 2005, Journal of the National Cancer Institute.

Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism.

W. Plunkett, H. Pelicano, Peng Huang, 2008, Blood.

Action of (E)-2'-deoxy-2'-(fluoromethylene)cytidine on DNA metabolism: incorporation, excision, and cellular response.

W. Plunkett, G. Achanta, H. Pelicano, 2002, Molecular pharmacology.

Alterations of mitochondrial biogenesis in chronic lymphocytic leukemia cells with loss of p53.

C. Croce, H. Pelicano, Peng Huang, 2016, Mitochondrion.

Alterations of cellular redox state during NNK-induced malignant transformation and resistance to radiation.

J. Colacino, Jinsong Liu, H. Pelicano, 2008, Antioxidants & redox signaling.

Mitochondrial Dysfunction and Reactive Oxygen Species Imbalance Promote Breast Cancer Cell Motility through a CXCL 14-Mediated Mechanism

H. Pelicano, Peng Huang, Yan Zhou, 2009 .

Mitochondrial dysfunction and reactive oxygen species imbalance promote breast cancer cell motility through a CXCL14-mediated mechanism.

H. Pelicano, Peng Huang, Yan Zhou, 2009, Cancer research.

Novel Role of NOX in Supporting Aerobic Glycolysis in Cancer Cells with Mitochondrial Dysfunction and as a Potential Target for Cancer Therapy

Huamin Wang, Hua Wang, Jinsong Liu, 2012, PLoS biology.

Effective elimination of chronic lymphocytic leukemia cells in the stromal microenvironment by a novel drug combination strategy using redox-mediated mechanisms

H. Pelicano, Jun-yi Zeng, Wan Zhang, 2015, Molecular medicine reports.

Targeting p53-deficient chronic lymphocytic leukemia cells in vitro and in vivo by ROS-mediated mechanism

Jie Huang, H. Pelicano, Peng Huang, 2016, Oncotarget.

A Novel Mechanism of Action of Methyl-2-cyano-3,12 Dioxoolean-1,9 Diene-28-oate: Direct Permeabilization of the Inner Mitochondrial Membrane to Inhibit Electron Transport and Induce Apoptosis

M. Konopleva, M. Andreeff, I. Samudio, 2005, Molecular Pharmacology.

pathway in human chronic lymphocytic leukemia cells Hu1D10 induces apoptosis concurrent with activation of the AKT survival

J. Byrd, H. Pelicano, Peng Huang, 2011 .

Hu1D10 induces apoptosis concurrent with activation of the AKT survival pathway in human chronic lymphocytic leukemia cells.

J. Byrd, A. Johnson, H. Pelicano, 2004, Blood.

Hu 1 D 10 induces apoptosis concurrent with activation of the AKT survival pathway in human chronic lymphocytic leukemia cells

J. Byrd, A. Johnson, H. Pelicano, 2004 .

Novel action of paclitaxel against cancer cells: bystander effect mediated by reactive oxygen species.

H. Pelicano, Peng Huang, Weiqin Lu, 2007, Cancer research.

Loss of p53 and altered miR15-a/16-1MCL-1 pathway in CLL: insights from TCL1-Tg:p53−/− mouse model and primary human leukemia cells

L. Feng, C. Croce, H. Pelicano, 2014, Leukemia.

Role of p53 in cellular response to anticancer nucleoside analog-induced DNA damage.

L. Feng, W. Plunkett, G. Achanta, 2000, International journal of molecular medicine.

Synthesis, in vitro antiviral evaluation, and stability studies of bis(S-acyl-2-thioethyl) ester derivatives of 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA) as potential PMEA prodrugs with improved oral bioavailability.

H. Pelicano, J. Imbach, A. Aubertin, 1996, Journal of medicinal chemistry.

Equal inhibition of the replication of human immunodeficiency virus in human T-cell culture by ddA bis(SATE)phosphotriester and 3'-azido-2',3'-dideoxythymidine.

H. Pelicano, J. Imbach, A. Aubertin, 1994, Biochemical pharmacology.

Stabilization of p53 is a novel mechanism for proapoptotic function of NF-kappaB.

Douglas B. Evans, Wei Zhang, J. Abbruzzese, 2004, Journal of Biological Chemistry.

Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy.

R. Davis, L. Garraway, Jing Wang, 2018, Cell metabolism.

Enzymatic properties of the unnatural beta-L-enantiomers of 2',3'-dideoxyadenosine and 2',3'-didehydro-2',3'-dideoxyadenosine.

H. Pelicano, S. Eriksson, J. Imbach, 1997, Journal of medicinal chemistry.

A new synthesis of some 4'-thio-D-ribonucleosides and preliminary enzymatic evaluation

H. Pelicano, L. Bellon, J. Imbach, 1994 .

Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate.

Jinsong Liu, G. Achanta, H. Pelicano, 2006, Cancer cell.

Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia.

Peng Huang, Li Feng, Michael J Keating, 2005, Cancer research.

Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukemia

C. Croce, W. Plunkett, H. Pelicano, 2012, Nature Cell Biology.

Excision of b - D - and b - L -Nucleotide Analogs from DNA by the Human Cytosolic 3 9 -to-5 9 Exonuclease

H. Pelicano, M. Kukhanova, Yung‐chi Cheng, 2000 .

Excision of β-D- and β-L-nucleotide analogs from DNA by the human cytosolic 3'-to-5' exonuclease

H. Pelicano, M. Kukhanova, Yung‐chi Cheng, 2000 .

Synthesis and HIV-1 reverse transcriptase inhibition properties of two new methylenephosphonate analogues of 3′-azido-3′-deoxythymidine-5′-triphosphate

H. Pelicano, J. Imbach, P. Labataille, 1995 .

Study of the substrate-binding properties of bovine liver adenosine kinase and inhibition by fluorescent nucleoside analogues.

R. Goody, H. Pelicano, G. Divita, 1997, European journal of biochemistry.

Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol γ

G. Achanta, H. Pelicano, Peng Huang, 2005, The EMBO journal.

Synthesis and HIV-1 Reverse Transcriptase Inhibition Properties of Two New Methylenephosphonate Analogues of 3′-Azido-3′-deoxythymidine-5′- triphosphate.

H. Pelicano, J. Imbach, P. Labataille, 1996 .

Redox Regulation of Stem-like Cells Though the CD44v-xCT Axis in Colorectal Cancer: Mechanisms and Therapeutic Implications

W. Jia, H. Pelicano, R. Xu, 2016, Theranostics.

Long non-coding RNA UICLM promotes colorectal cancer liver metastasis by acting as a ceRNA for microRNA-215 to regulate ZEB 2 expression

Fenghua Wang, Yu-hong Li, Z. Pan, 2017 .

Long non-coding RNA UICLM promotes colorectal cancer liver metastasis by acting as a ceRNA for microRNA-215 to regulate ZEB2 expression

Fenghua Wang, Yu-hong Li, Z. Pan, 2017, Theranostics.

Elimination of Chronic Lymphocytic Leukemia Cells in Stromal Microenvironment by Targeting CPT with an Anti-Angina Drug Perhexiline

C. Croce, Z. Estrov, Wen-Qi Jiang, 2016, Oncogene.

microRNA-217 inhibits tumor progression and metastasis by downregulating EZH2 and predicts favorable prognosis in gastric cancer

Wei Zhang, Fenghua Wang, Yu-hong Li, 2015, Oncotarget.

Mitochondrial dysfunction in some triple-negative breast cancer cell lines: role of mTOR pathway and therapeutic potential

L. Pusztai, H. Pelicano, Peng Huang, 2014, Breast Cancer Research.

SelectivekillingofoncogenicallytransformedcellsthroughaROS- mediated mechanism by b-phenylethyl isothiocyanate

Jinsong Liu, G. Achanta, H. Pelicano, 2006 .

Respiratory Defect and Hypoxia Overcome Drug Resistance Associated with Mitochondrial Inhibition of Glycolysis in Cancer Cells : A Novel Strategy to Updated

K. Bhalla, H. Pelicano, Peng Huang, 2005 .

Targeting Hsp90 by 17-AAG in leukemia cells: mechanisms for synergistic and antagonistic drug combinations with arsenic trioxide and Ara-C

M. Andreeff, W. Plunkett, H. Pelicano, 2006, Leukemia.

Aberrant FGFR Tyrosine Kinase Signaling Enhances the Warburg Effect by Reprogramming LDH Isoform Expression and Activity in Prostate Cancer.

Chin-Lee Wu, H. Pelicano, Peng Huang, 2018, Cancer research.

Identification of MicroRNA‐214 as a negative regulator of colorectal cancer liver metastasis by way of regulation of fibroblast growth factor receptor 1 expression

Peng Huang, Fenghua Wang, Yu-hong Li, 2014, Hepatology.

Stabilization of p53 Is a Novel Mechanism for Proapoptotic Function of NF-κB*

Peng Huang, Christian Schmidt, James L. Abbruzzese, 2004, Journal of Biological Chemistry.

human tumor cells function and enhanced glycolysis dependency in between attenuated mitochondrial bioenergetic Multiparameter metabolic analysis reveals a close link

Min Wu, H. Pelicano, P. Huang, 2009 .

K-rasG12V transformation leads to mitochondrial dysfunction and a metabolic switch from oxidative phosphorylation to glycolysis

G. Garcia-Manero, H. Pelicano, P. Chiao, 2011, Cell Research.

Cancer metabolism: is glutamine sweeter than glucose?

H. Pelicano, Peng Huang, Weiqin Lu, 2010, Cancer cell.

Simultaneous inhibition of PDK1/AKT and Fms-like tyrosine kinase 3 signaling by a small-molecule KP372-1 induces mitochondrial dysfunction and apoptosis in acute myelogenous leukemia.

G. Mills, Yiling Lu, M. Konopleva, 2006, Cancer research.

Targeting the autophagy in bone marrow stromal cells overcomes resistance to vorinostat in chronic lymphocytic leukemia

H. Pelicano, Jun-yi Zeng, Wan Zhang, 2018, OncoTargets and therapy.

Targeting Mitochondria of Cancer Cells: Mechanisms and Compounds

H. Pelicano, Peng Huang, M. Ogasawara, 2014 .

Long non-coding RNA XIST regulates gastric cancer progression by acting as a molecular sponge of miR-101 to modulate EZH2 expression

Fenghua Wang, Yu-hong Li, H. Pelicano, 2016, Journal of Experimental & Clinical Cancer Research.

Novel role of p 53 in maintaining mitochondrial genetic stability through interaction with DNA Pol c

G. Achanta, H. Pelicano, Peng Huang, 2005 .

Novel Role of NOX in Supporting Aerobic Glycolysis in Cancer Cells with Mitochondrial Dysfunction and as a Potential Target for Cancer Therapy

Huamin Wang, Jinsong Liu, H. Pelicano, 2012, PLoS biology.

The Circadian Gene Period2 Plays an Important Role in Tumor Suppression and DNA-Damage Response In Vivo

Jinsong Liu, L. Fu, H. Pelicano, 2002, Cell.

Antibody-induced nonapoptotic cell death in human lymphoma and leukemia cells is mediated through a novel reactive oxygen species-dependent pathway.

H. Pelicano, T. Illidge, M. Cragg, 2012, Blood.

Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism

Wei Zhang, Limei Hu, L. Ramdas, 2006, The Journal of cell biology.

Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism.

W. Plunkett, H. Pelicano, Peng Huang, 2008, Blood.

Identification of MicroRNA‐214 as a negative regulator of colorectal cancer liver metastasis by way of regulation of fibroblast growth factor receptor 1 expression

Fenghua Wang, Yu-hong Li, H. Pelicano, 2014, Hepatology.

[Resistance of chronic lymphocytic leukemia cells in apoptosis: key role of stromal cells in maintaining the redox potential of CLL cells].

H. Pelicano, W. Zhang, Liao Feng, 2013, Medecine sciences : M/S.

Abstract 4560: Targeting chronic lymphocytic leukemia with p53 deficiency with phenethyl isothiocyanate

H. Pelicano, Jinyun Liu, Gang Chen, 2015 .

Aberrant FGFR Tyrosine Kinase Signaling Enhances the Warburg Effect by Reprogramming LDH Isoform Expression and Activity in Prostate Cancer.

Chin-Lee Wu, H. Pelicano, Peng Huang, 2018, Cancer research.