T. Devereux

Jack A. Taylor, J. Taylor, T. Devereux, 1995, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

DNA methylation analysis of the promoter region of the human telomerase reverse transcriptase (hTERT) gene.

J. Barrett, C. Afshari, I. Horikawa, 1999, Cancer research.

Predominant p53 G→A Transition Mutation and Enhanced Cell Proliferation in Uterine Sarcomas of CBA Mice Treated with 1,2-Dimethylhydrazine

T. Devereux, G. Boorman, R. Sills, 1998, Toxicologic pathology.

Identification of cytochrome P-450 isozymes in nonciliated bronchiolar epithelial (Clara) and alveolar type II cells isolated from rabbit lung.

C. Wolf, T. Devereux, C. Serabjit-Singh, 1981, Experimental lung research.

High Frequency of Ras Mutations in Forestomach and Lung Tumors of B6C3F1 Mice Exposed to 1-Amino-2,4-dibromoanthraquinone for 2 Years

J. Huff, R. Maronpot, K. Toyoda, 2001, Toxicologic pathology.

Proto-oncogene activation in liver tumors of hepatocarcinogenesis-resistant strains of mice.

P. Lord, R. Maronpot, T. Orton, 1992, Carcinogenesis.

High frequency of K-ras mutations in spontaneous and vinyl carbamate-induced lung tumors of relatively resistant B6CF1 (C57BL/6J x BALB/cJ) mice.

Marshall W. Anderson, R. Maronpot, T. Massey, 1995, Carcinogenesis.

Isolation and identification of clara cells from rabbit lung

T. Devereux, J. Fouts, 1980, In Vitro.

Protooncogene activation in spontaneously occurring and chemically induced rodent and human lung tumors.

M. You, T. Devereux, J. Wiest, 1992, Progress in clinical and biological research.

Molecular profiling of mouse lung tumors: association with tumor progression, lung development, and human lung adenocarcinomas

M. You, T. Devereux, R. Lubet, 2004, Oncogene.

Hypermethylation of the p 16 Ink 4 a promoter in B 6 C 3 F 1 mouse primary lung adenocarcinomas and mouse lung cell lines

J. Barrett, F. Tyson, J. Foley, 2000 .

Role of Clara cells and type II cells in the development of pulmonary tumors in rats and mice following exposure to a tobacco-specific nitrosamine.

S. Belinsky, R. Maronpot, J. Foley, 1991, Experimental lung research.

Role of DNA methylation in the activation of proto-oncogenes and the induction of pulmonary neoplasia by nitrosamines.

S. Belinsky, T. Devereux, M. Anderson, 1990, Mutation research.

Predominant K-ras Codon 12 G → A Transition in Chemically Induced Lung Neoplasms in B6C3F1 Mice

T. Devereux, R. Sills, J. Dunnick, 2004, Toxicologic pathology.

Homozygous deletions at chromosome 9p21 and mutation analysis of p16 and p15 in microdissected primary non-small cell lung cancers.

J. Barrett, J. Taylor, T. Devereux, 1995, Clinical cancer research : an official journal of the American Association for Cancer Research.

FINE MAPPING AND CHARACTERIZATION OF CANDIDATE LUNG TUMOR RESISTANCE GENES FOR THE Par2 LOCUS ON MOUSE CHROMOSOME 18

M. You, T. Devereux, Yian Wang, 2000, Experimental lung research.

Xenobiotic metabolism in human alveolar type II cells isolated by centrifugal elutriation and density gradient centrifugation.

T. Massey, T. Devereux, J. Yankaskas, 1986, Cancer research.

DNA adducts as a dosimeter for risk estimation.

S. Belinsky, T. Devereux, M. Anderson, 1987, Environmental health perspectives.

Separation and characterization of hepatocytes from immature and adult rats into distinct subpopulations by centrifugal elutriation.

T. Devereux, J. Fouts, W. Klinger, 1988, Experimental pathology.

Functional hepatocellular heterogeneity determined by the hepatotoxins allyl alcohol and bromobenzene in immature and adult Fischer 344 rats.

R. Maronpot, T. Devereux, J. Fouts, 1986, Toxicology and applied pharmacology.

Ras proto-oncogene activation in liver and lung tumors from B6C3F1 mice exposed chronically to methylene chloride.

R. Maronpot, J. Foley, T. Devereux, 1993, Carcinogenesis.

Cell selective alkylation of DNA in rat lung following low dose exposure to the tobacco specific carcinogen 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone.

S. Belinsky, J. Swenberg, T. Devereux, 1987, Cancer research.

Functional and structural zonal hepatocyte heterogeneity--dynamics and ontogenic development.

T. Devereux, J. Fouts, W. Klinger, 1988, Experimental pathology.

Mutations of ras Protooncogenes and p53 Tumor Suppressor Gene in Cardiac Hemangiosarcomas from B6C3F1 Mice Exposed to 1,3-Butadiene for 2 Years

R. Melnick, T. Devereux, G. Boorman, 2000, Toxicologic pathology.

Sequence and chromosomal mapping of the mouse homolog (Madh4) of the human DPC4/MADH4 gene

T. Devereux, C. Anna, 1997, Mammalian Genome.

Role of ras protooncogene activation in the formation of spontaneous and nitrosamine-induced lung tumors in the resistant C3H mouse.

Marshall W. Anderson, S. Belinsky, T. Devereux, 1991, Carcinogenesis.

An additional 136 SSLP markers typed for the AXB and BXA recombinant inbred mouse strains

K. Svenson, J. Naggert, M. You, 1997, Mammalian Genome.

Point mutations of K-ras and H-ras genes in forestomach neoplasms from control B6C3F1 mice and following exposure to 1,3-butadiene, isoprene or chloroprene for up to 2-years.

R. Melnick, T. Devereux, G. Boorman, 2001, Chemico-biological interactions.

High frequency of codon 61 K-ras A-->T transversions in lung and Harderian gland neoplasms of B6C3F1 mice exposed to chloroprene (2-chloro-1,3-butadiene) for 2 years, and comparisons with the structurally related chemicals isoprene and 1,3-butadiene.

R. Melnick, T. Devereux, G. Boorman, 1999, Carcinogenesis.

Frequency of ras Mutations in Liver Neoplasms from B6C3F1 Mice Exposed to Tetrafluoroethylene for Two Years

T. Devereux, G. Boorman, R. Sills, 1998, Toxicologic pathology.

Factors regulating activation and DNA alkylation by 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and nitrosodimethylamine in rat lung and isolated lung cells, and the relationship to carcinogenicity.

S. Belinsky, T. Devereux, M. Anderson, 1988, Cancer research.

The cytochrome P-450 monooxygenase system of rabbit lung enzyme components, activities, and induction in the nonciliated bronchiolar epithelial (Clara) cell, alveolar type II cell, and alveolar macrophage.

T. Devereux, R. Philpot, B. Domin, 1986, Molecular pharmacology.

Isolation of pulmonary cells and use in studies of xenobiotic metabolism.

T. Devereux, J. Fouts, 1981, Methods in enzymology.

Hepatic microsomal N-hydroxylation of p-chloroaniline and p-chloro-N-methylaniline in red-winged blackbird compared with rat.

T. Devereux, J. Fouts, H. Pan, 1979, Xenobiotica; the fate of foreign compounds in biological systems.

Activation of K-ras in aflatoxin B1-induced lung tumors from AC3F1 (A/J x C3H/HeJ) mice.

R. Maronpot, T. Massey, J. Foley, 1996, Carcinogenesis.

Hepatic and pulmonary carcinogenicity of methylene chloride in mice: a search for mechanisms.

M. Hegi, J. Kanno, R. Maronpot, 1995, Toxicology.

Allelotype analysis of mouse lung carcinomas reveals frequent allelic losses on chromosome 4 and an association between allelic imbalances on chromosome 6 and K-ras activation.

E. Lander, W. Dietrich, M. Hegi, 1994, Cancer research.

Developmental aspects of hepatic and extrahepatic drug-metabolizing enzyme systems: microsomal enzymes and components in rabbit liver and lung during the first month of life.

T. Devereux, J. Fouts, 1972, The Journal of pharmacology and experimental therapeutics.

A PCR-RFLP Method for the Detection of Helicobacter hepaticus in Frozen or Fixed Liver from B6C3F1 Mice

T. Devereux, D. Malarkey, J. R. Hailey, 1997, Toxicologic pathology.

Increased frequency of K-ras mutations in lung neoplasms from female B6C3F1 mice exposed to ozone for 24 or 30 months.

A. Greenwell, T. Devereux, G. Boorman, 1995, Carcinogenesis.

Hepatocarcinogenicity of chlordane in B6C3F1 and B6D2F1 male mice: evidence for regression in B6C3F1 mice and carcinogenesis independent of ras proto-oncogene activation.

G. Dinse, R. Maronpot, T. Devereux, 1995, Carcinogenesis.

Tissue and cellular differences in the expression of cytochrome P-450 isozymes

T. Devereux, C. Serabjit-Singh, J. Bend, 1984 .

Genetic alterations in the Catnb gene but not the H-ras gene in hepatocellular neoplasms and hepatoblastomas of B6C3F(1) mice following exposure to diethanolamine for 2 years.

J. Haseman, T. Devereux, R. Irwin, 2003, Chemico-biological interactions.

CHAPTER 2 – XENOBIOTIC METABOLISM BY ISOLATED PULMONARY BRONCHIOLAR AND ALVEOLAR CELLS

T. Devereux, R. Philpot, B. Domin, 1993 .

Effect of dexamethasone treatment on N,N-dimethylaniline demethylation and N-oxidation in pulmonary microsomes from pregnant and fetal rabbits.

T. Devereux, J. Fouts, 1978, Biochemical pharmacology.

Hepatic microsomal N-oxidation and N-demethylation of N,N-dimethylaniline in red-winged blackbird compared with rat and other birds.

T. Devereux, J. Fouts, H. Pan, 1975, Life sciences.

Carcinogen-specific targeting of chromosome 12 for loss of heterozygosity in mouse lung adenocarcinomas: implications for chromosome instability and tumor progression

Marshall W. Anderson, M. You, R. Maronpot, 2004, Oncogene.

Xenobiotic metabolism by isolated pulmonary cells.

T. Devereux, R. Philpot, B. Domin, 1989, Pharmacology & therapeutics.

Xenobiotic metabolism by alveolar type II cells isolated from rabbit lung.

T. Devereux, J. Fouts, 1981, Biochemical pharmacology.

Metabolism of prostaglandin PG-F2 alpha by freshly isolated alveolar type II cells from lungs of adult male or pregnant rabbits.

T. Devereux, T. Eling, J. Fouts, 1987, Prostaglandins, leukotrienes, and medicine.

Relationship between the formation of promutagenic adducts and the activation of the K-ras protooncogene in lung tumors from A/J mice treated with nitrosamines.

S. Belinsky, R. Maronpot, T. Devereux, 1989, Cancer research.

Perturbations of the Ink4a/Arf gene locus in aflatoxin B1-induced mouse lung tumors.

R. Maronpot, T. Massey, A. S. Tam, 2003, Carcinogenesis.

Hypermethylation of the p16 (Ink4a) promoter in B6C3F1 mouse primary lung adenocarcinomas and mouse lung cell lines.

J. Barrett, F. Tyson, J. Foley, 2000, Carcinogenesis.

Molecular mechanisms of lung cancer. Interaction of environmental and genetic factors. Giles F. Filley Lecture.

J. Barrett, J. Taylor, T. Devereux, 1996, Chest.

Analysis of genetic alterations in uterine leiomyomas and leiomyosarcomas by comparative genomic hybridization

A. Berchuck, T. Ried, D. Dixon, 1997, Molecular carcinogenesis.

The putative tumor suppressor Tsc-22 is downregulated early in chemically induced hepatocarcinogenesis and may be a suppressor of Gadd45b.

T. Devereux, N. Walker, M. Iida, 2007, Toxicological sciences : an official journal of the Society of Toxicology.

o-Nitrotoluene-induced large intestinal tumors in B6C3F1 mice model human colon cancer in their molecular pathogenesis.

T. Devereux, G. Flake, G. Boorman, 2003, Carcinogenesis.

Additional evidence that the K-ras protooncogene is a candidate for the major mouse pulmonary adenoma susceptibility (Pas-1) gene.

K. Svenson, M. You, A. Malkinson, 1998, Experimental lung research.

Wildtype Kras2 can inhibit lung carcinogenesis in mice

Ming You, Kun-Liang Guan, Robert C. Sills, 2001, Nature Genetics.

Use of quantitative trait loci to map murine lung tumor susceptibility genes.

T. Devereux, N. Kaplan, 1998, Experimental lung research.

Carcinogenic induction directs the selection of allelic losses in mouse lung tumorigenesis.

M. You, C. R. Herzog, T. Devereux, 2002, Cancer research.

Gene Expression Studies Demonstrate that the K-ras/Erk MAP Kinase Signal Transduction Pathway and Other Novel Pathways Contribute to the Pathogenesis of Cumene-induced Lung Tumors

J. Parker, S. Belinsky, J. Collins, 2008, Toxicologic pathology.

ANALYSIS OF THE Par2 MODIFIER OF PULMONARY ADENOMA FORMATION IN MICE

M. You, T. Devereux, Yian Wang, 2005, Experimental lung research.

N-oxidation and demethylation of N,N-dimethylaniline by rabbit liver and lung microsomes. Effects of age and metals.

T. Devereux, J. Fouts, 1974, Chemico-biological interactions.

Overview of the Molecular Carcinogenesis of Mouse Lung Tumor Models of Human Lung Cancer

T. Devereux, R. Sills, H. Hong, 2007, Toxicologic pathology (Print).

Aberrant Promoter Hypermethylation of the Death-Associated Protein Kinase Gene Is Early and Frequent in Murine Lung Tumors Induced by Cigarette Smoke and Tobacco Carcinogens

S. Belinsky, T. Devereux, J. Hutt, 2004, Cancer Research.

Changes in global gene and protein expression during early mouse liver carcinogenesis induced by non-genotoxic model carcinogens oxazepam and Wyeth-14,643.

K. Tomer, R. Paules, S. Sieber, 2003, Carcinogenesis.

Analysis of activated protooncogenes in B6C3F1 mouse liver tumors induced by ciprofibrate, a potent peroxisome proliferator.

M. Hegi, S. Belinsky, T. Fox, 1993, Carcinogenesis.

Genetic Alterations in Brain Tumors Following 1,3-Butadiene Exposure in B6C3F1 Mice

R. Melnick, M. Hegi, T. Devereux, 2005, Toxicologic pathology.

Mutation of β-catenin is an early event in chemically induced mouse hepatocellular carcinogenesis

J. Barrett, J. Foley, T. Devereux, 1999, Oncogene.

Comparison of pulmonary O6‐methylguanine dna adduct levels and Ki‐ras activation in lung tumors from resistant and susceptible mouse strains

Marshall W. Anderson, A. Greenwell, M. Hegi, 1993, Molecular carcinogenesis.

The effect of Hg2+ on rabbit hepatic and pulmonary solubilized, partially purified N,N-dimethylaniline N-oxidases.

T. Devereux, R. Philpot, J. Fouts, 1977, Chemico-biological interactions.

Effect of pregnancy or treatment with cetain steroids on N,N-dimethylaniline demethylation and N-oxidation by rabbit liver or lung microsomes.

T. Devereux, J. Fouts, 1975, Drug metabolism and disposition: the biological fate of chemicals.

Foreign compound metabolism by isolated cells from rabbit lung.

G. Hook, T. Devereux, J. Fouts, 1979, Drug metabolism and disposition: the biological fate of chemicals.

Cytochrome P-450 monooxygenase, epoxide hydrolase and flavin monooxygenase activities in clara cells and alveolar type II cells isolated from rabbit

T. Devereux, J. Diliberto, J. Fouts, 2004, Cell Biology and Toxicology.

Prostaglandin synthetase and cytochrome P-450-dependent metabolism of (+/-)benzo(a)pyrene 7,8-dihydrodiol by enriched populations of rat Clara cells and alveolar type II cells.

T. Devereux, T. Eling, K. Jones, 1983, Cancer research.

Use of 10-sec sonication of homogenates to increase microsomal protein yield in liver and lung from young and adult Dutch Belt rabbits.

T. Devereux, J. Fouts, 1973, Biochemical pharmacology.

Characteristics and development of drug metabolism by pulmonary microsomes

T. Devereux, M. James, J. Bend, 1976, Agents and Actions.

Metabolism of 2-acetylaminofluorene by clara cells, type II cells and alveolar macrophages isolated from rabbit lung, and use of a new chamber incubation mutagenicity test system

T. Devereux, T. Aune, Kristi Tveito, 1985, Cell Biology and Toxicology.

A PROCEDURE FOR ISOLATION OF RABBIT PULMONARY EPITHELIAL CELLS FOR STUDY OF FOREIGN COMPOUND METABOLISM

T. Devereux, J. Fouts, 1980 .

Major carcinogenic pathways identified by gene expression analysis of peritoneal mesotheliomas following chemical treatment in F344 rats.

L. Crosby, R. Paules, J. Collins, 2006, Toxicology and applied pharmacology.

Assignment of a locus for mouse lung tumor susceptibility to proximal Chromosome 19

R. Maronpot, J. Foley, T. Devereux, 1994, Mammalian Genome.

At least four loci and gender are associated with susceptibility to the chemical induction of lung adenomas in A/J x BALB/c mice.

M. You, A. Malkinson, A. Yang, 1998, Genomics.

Pol ι Is a Candidate for the Mouse Pulmonary Adenoma Resistance 2 Locus, a Major Modifier of Chemically Induced Lung Neoplasia

T. Kunkel, M. You, H. Vikis, 2004, Cancer Research.

CTNNB1 mutations and β‐catenin protein accumulation in human hepatocellular carcinomas associated with high exposure to aflatoxin B1 †

Jack A. Taylor, M. Stern, S. London, 2001, Molecular carcinogenesis.

Beta-catenin mutations and protein accumulation in all hepatoblastomas examined from B6C3F1 mice treated with anthraquinone or oxazepam.

J. Foley, T. Devereux, R. Sills, 2000, Cancer research.

Considerations concerning the murine hepatocarcinogenicity of selected chlorinated hydrocarbons.

G. Lucier, R. Maronpot, T. Devereux, 1995, Progress in clinical and biological research.

Physicochemical and immunochemical characterization of a binding-protein for PCB methyl sulfones

J. Gustafsson, T. Devereux, J. Lund, 1987 .

Mutations in ras genes in experimental tumours of rodents.

T. Devereux, G. Boorman, R. Sills, 1999, IARC scientific publications.

Evaluation of genetic alterations in cancer-related genes in lung and brain tumors from B6C3F1 mice exposed to 1,3-butadiene or chloroprene.

R. Melnick, T. Devereux, R. Sills, 2007, Chemico-biological interactions.

Map kinase activation correlates with K-ras mutation and loss of heterozygosity on chromosome 6 in alveolar bronchiolar carcinomas from B6C3F1 mice exposed to vanadium pentoxide for 2 years.

T. Devereux, R. Sills, C. Anna, 2002, Carcinogenesis.

H-ras oncogene mutation spectra in B6C3F1 and C57BL/6 mouse liver tumors provide evidence for TCDD promotion of spontaneous and vinyl carbamate-initiated liver cells.

R. Maronpot, T. Devereux, D. Malarkey, 1995, Carcinogenesis.

Expression of potential beta-catenin targets, cyclin D1, c-Jun, c-Myc, E-cadherin, and EGFR in chemically induced hepatocellular neoplasms from B6C3F1 mice.

T. Devereux, R. Sills, M. Iida, 2003, Toxicology and applied pharmacology.

Chemical-specific alterations in ras, p53, and beta-catenin genes in hemangiosarcomas from B6C3F1 mice exposed to o-nitrotoluene or riddelliine for 2 years.

T. Devereux, R. Sills, J. Dunnick, 2003, Toxicology and applied pharmacology.

Mutations and altered expression of the human cancer genes: what they tell us about causes.

J. Barrett, T. Devereux, J. Risinger, 1999, IARC scientific publications.

Comparison of pulmonary O6‐methylguanine dna adduct levels and Ki‐ras activation in lung tumors from resistant and susceptible mouse strains

Marshall W. Anderson, A. Greenwell, M. Hegi, 1993, Molecular carcinogenesis.

Low frequency of H-ras mutations in hepatocellular adenomas and carcinomas and in hepatoblastomas from B6C3F1 mice exposed to oxazepam in the diet.

J. Bucher, R. Maronpot, T. Devereux, 1994, Carcinogenesis.

Biotransformation of xenobiotics in individual rabbit hepatocytes. Application of microspectrofluorometry.

T. Massey, T. Devereux, J. Fouts, 1986, Drug metabolism and disposition: the biological fate of chemicals.

Genetic alterations in K‐ras and p53 cancer genes in lung neoplasms from Swiss (CD‐1) male mice exposed transplacentally to AZT

T. Devereux, R. Sills, J. Dunnick, 2007, Environmental and molecular mutagenesis.