A. Blasina

发表

Caffeine inhibits the checkpoint kinase ATM

B. Price, A. Blasina, Gaetan A. Turenne, 1999, Current Biology.

ATR-Chk1 pathway inhibition promotes apoptosis after UV treatment in primary human keratinocytes: potential basis for the UV protective effects of caffeine.

T. Heffernan, A. Conney, A. Blasina, 2009, The Journal of investigative dermatology.

PF-04691502, a Potent and Selective Oral Inhibitor of PI3K and mTOR Kinases with Antitumor Activity

Aileen McHarg, Jing Yuan, Peter K. Vogt, 2011, Molecular Cancer Therapeutics.

Breaching the DNA damage checkpoint via PF-00477736, a novel small-molecule inhibitor of checkpoint kinase 1

P. O'Connor, A. Blasina, J. Register, 2008, Molecular Cancer Therapeutics.

The role of inhibitory phosphorylation of CDC2 following DNA replication block and radiation-induced damage in human cells.

E. S. Paegle, A. Blasina, C. McGowan, 1997, Molecular biology of the cell.

Structure-Based Design of (5-Arylamino-2H-pyrazol-3-yl)-biphenyl-2‘,4‘-diols as Novel and Potent Human CHK1 Inhibitors

Enhong Chen, Ping Chen, Karen Lundgren, 2007 .

Human Mus81-associated endonuclease cleaves Holliday junctions in vitro.

P. Russell, J. Vialard, A. Blasina, 2001, Molecular cell.

Combined gemcitabine and CHK1 inhibitor treatment induces apoptosis resistance in cancer stem cell-like cells enriched with tumor spheroids from a non-small cell lung cancer cell line

Zhou Zhu, A. Blasina, T. Vanarsdale, 2013, Frontiers of Medicine.

A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase

A. Blasina, C. McGowan, A. Parker, 1999, Current Biology.

Molecular Medicine in Practice PF-04691502 , a Potent and Selective Oral Inhibitor of PI 3 K and mTOR Kinases with Antitumor Activity

J. Christensen, P. Vogt, A. Blasina, 2011 .

Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1

A. Blasina, C. McGowan, R. Melchionna, 2000, Nature Cell Biology.

Chemogenetic Evaluation of the Mitotic Kinesin CENP-E Reveals a Critical Role in Triple-Negative Breast Cancer

Zhou Zhu, P. Kung, A. Blasina, 2014, Molecular Cancer Therapeutics.

Companion Diagnostics and Cancer Biomarkers Chemogenetic Evaluation of the Mitotic Kinesin CENP-E Reveals a Critical Role in Triple-Negative Breast Cancer

Zhou Zhu, P. Kung, A. Blasina, 2014 .

TheRoleofInhibitory Phosphorylation ofCDC2 following DNA Replication BlockandRadiation- induced DamageinHumanCells

A. Blasina, 1997 .

Role of TrfA and DnaA Proteins in Origin Opening during Initiation of DNA Replication of the Broad Host Range Plasmid RK2*

D. Helinski, A. Blasina, K. Doran, 1997, The Journal of Biological Chemistry.

Cdc25 inhibited in vivo and in vitro by checkpoint kinases Cds1 and Chk1.

P. Russell, A. Blasina, C. McGowan, 1999, Molecular biology of the cell.

Oxidative lesion to membrane proteins in senescent erythrocytes.

A. Blasina, A. Brovelli, C. Balduini, 1990, Biomedica biochimica acta.

DNA damage checkpoint control of mitosis in fission yeast.

N. Rhind, P. Russell, A. Blasina, 2000, Cold Spring Harbor symposia on quantitative biology.

Mitotic Checkpoint Kinase Mps1 Has a Role in Normal Physiology which Impacts Clinical Utility

Zhou Zhu, S. Murphy, Sergei L Timofeevski, 2015, PloS one.

Imaging with FLT-PET demonstrates that PF-477736, an inhibitor of CHK1 kinase, overcomes a cell cycle checkpoint induced by gemcitabine in PC-3 xenografts.

G. McArthur, A. Blasina, R. Hicks, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phase I clinical trial of gemcitabine (GEM) in combination with PF-00477736 (PF-736), a selective inhibitor of CHK1 kinase.

K. Wilner, G. Schwartz, C. Britten, 2010 .

Copy-up mutants of the plasmid RK2 replication initiation protein are defective in coupling RK2 replication origins.

D. Helinski, A. Blasina, A. Toukdarian, 1996, Proceedings of the National Academy of Sciences of the United States of America.