M. Tagawa

Hiroshi Kobayashi, M. Tagawa, H. Shimada, 2012, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

A Gene Medicine with the Midkine-mediated Transcriptional Regulation as New Cancer Therapeutics

M. Tagawa, H. Shimada, K. Hiroshima, 2012 .

Zoledronic Acid Produces Antitumor Effects on Mesothelioma Through Apoptosis and S-Phase Arrest in p53-Independent and Ras prenylation-Independent Manners

Hiroshi Kobayashi, M. Tagawa, H. Shimada, 2012, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Complete regression of human malignant mesothelioma xenografts following local injection of midkine promoter‐driven oncolytic adenovirus

H. Okamura, M. Tagawa, N. Kasahara, 2010, The journal of gene medicine.

Cytologic Differential Diagnosis of Malignant Mesothelioma and Reactive Mesothelial Cells With FISH Analysis of p16

A. Marchevsky, M. Tagawa, H. Shimada, 2016, Diagnostic cytopathology.

Reduced tumorigenicity of human gastric carcinoma cells engineered to produce IL-2 in SCID mice reconstituted with peripheral blood cells from cancer patients.

H. Matsubara, M. Tagawa, S. Sakiyama, 1998, Cancer letters.

An image cytometric technique is a concise method to detect adenoviruses and host cell proteins and to monitor the infection and cellular responses induced

M. Shingyoji, M. Tagawa, H. Shimada, 2017, Virology Journal.

Fas ligand-expressing tumors induce tumor-specific protective immunity in the inoculated hosts but vaccination with the apoptotic tumors suppresses antitumor immunity

M. Tagawa, S. Sakiyama, T. Kuriyama, 2003, Cancer Gene Therapy.

Resistance to apoptosis induced by microenvironmental stresses is correlated with metastatic potential in Lewis lung carcinoma

M. Tagawa, K. Takenaga, Y. Tada, 1999, Clinical & Experimental Metastasis.

T-cell-dependent antitumor effects produced by CD40 ligand expressed on mouse lung carcinoma cells are linked with the maturation of dendritic cells and secretion of a variety of cytokines

M. Tagawa, S. Sakiyama, T. Kuriyama, 2003, Cancer Gene Therapy.

Expression of novel DNA-binding protein with zinc finger structure in various tumor cells.

H. Matsubara, K. Shigemoto, T. Ito, 1990, The Journal of biological chemistry.

Secretion of interleukin-10 from murine colon carcinoma cells suppresses systemic antitumor immunity and impairs protective immunity induced against the tumors

M. Tagawa, S. Sakiyama, K. Kawamura, 2002, Cancer Gene Therapy.

Anti-tumor immunity elicited by direct intratumoral administration of a recombinant adenovirus expressing either IL-28A/IFN-λ2 or IL-29/IFN-λ1

M. Tagawa, K. Takagi, Y. Nishioka, 2016, Cancer Gene Therapy.

A Possible Anticancer Agent, Type III Interferon, Activates Cell Death Pathways and Produces Antitumor Effects

M. Tagawa, H. Shimada, K. Hiroshima, 2011, Clinical & developmental immunology.

Protective immunity is induced in murine colon carcinoma cells by the expression of interleukin-12 or interleukin-18, which activate type 1 helper T cells

Hiroshi Yamamoto, M. Tagawa, S. Sakiyama, 2000, Cancer Gene Therapy.

Impaired tumorigenicity of human pancreatic cancer cells retrovirally transduced with interleukin-12 or interleukin-15 gene

Hiroshi Yamamoto, M. Tagawa, S. Sakiyama, 2000, Cancer Gene Therapy.

Fiber-substituted conditionally replicating adenovirus for oncolysis of human renal carcinoma cells.

A. Gotoh, M. Tagawa, T. Nishizaki, 2012, Anticancer research.

Virology- and immunology-based gene therapy for cancer

M. Tagawa, H. Shimada, N. Suzuki, 2006, Cancer Immunology, Immunotherapy.

Effects of neuropeptide analogues on calcium flux and proliferation in lung cancer cell lines.

P. Bunn, M. Tagawa, J. Stewart, 1994, Cancer research.

Neuropeptide signal transduction in lung cancer: clinical implications of bradykinin sensitivity and overall heterogeneity.

P. Bunn, M. Tagawa, P. Jewett, 1992, Cancer research.

Acquired immunity in nude mice induced by expression of the IL‐2 or IL‐4 gene in human pancreatic carcinoma cells and anti‐tumor effect generated by In vivo gene transfer using retrovirus

M. Tagawa, S. Sakiyama, Taketo Yamaguchi, 1999, International journal of cancer.

Advances in Brief DNA Polymerase k , Implicated in Spontaneous and DNA Damage-induced Mutagenesis , Is Overexpressed in Lung Cancer 1

M. Tagawa, S. Sakiyama, H. Ohmori, 2001 .

Combinatory cytotoxic effects produced by E1B-55kDa-deleted adenoviruses and chemotherapeutic agents are dependent on the agents in esophageal carcinoma

M. Tagawa, H. Shimada, N. Suzuki, 2010, Cancer Gene Therapy.

Cytotoxicity of adenoviruses expressing the wild-type p53 gene to esophageal carcinoma cells is linked with the CAR expression level and indirectly with the endogenous p53 status

M. Tagawa, M. Namba, H. Shimada, 2009, Cancer Gene Therapy.

Cytotoxic effects of replication-competent adenoviruses on human esophageal carcinoma are enhanced by forced p53 expression

Hiroshi Kobayashi, M. Shingyoji, M. Tagawa, 2015, BMC Cancer.

Distinct roles of BCNP1 in B cell development and activation.

T. Tsubata, M. Tagawa, M. Hikida, 2020, International immunology.

Induction of systemic immunity by expression of interleukin‐23 in murine colon carcinoma cells

Hiroshi Yamamoto, M. Tagawa, Taketo Yamaguchi, 2003, International journal of cancer.

Expression of the TNF-alpha gene on mouse lung carcinoma cells suppresses spontaneous lung metastasis without affecting tumorigenicity.

M. Tagawa, T. Kuriyama, K. Tatsumi, 2002, Oncology reports.

Expression of Interleukin‐22 in Murine Carcinoma Cells did not Influence Tumour Growth In Vivo but did Improve Survival of the Inoculated Hosts

L. Yu, M. Tagawa, T. Kuriyama, 2004, Scandinavian journal of immunology.

Correlation between interleukin 6 production and tumor proliferation in non-small cell lung cancer

M. Tagawa, K. Hiroshima, T. Iizasa, 2004, Cancer Immunology, Immunotherapy.

Expression of interleukin-21 and -23 in human esophageal tumors produced antitumor effects in nude mice.

M. Tagawa, B. Shan, O. Shimozato, 2004, Anticancer research.

Expression of the interleukin-21 gene in murine colon carcinoma cells generates systemic immunity in the inoculated hosts

M. Tagawa, S. Sakiyama, Taketo Yamaguchi, 2003, Cancer Gene Therapy.

Induced immunity by expression of interleukin-2 or GM-CSF gene in murine neuroblastoma cells can generate antitumor response to established tumors

M. Tagawa, S. Sakiyama, N. Ohnuma, 1999, Cancer Gene Therapy.

Immunogenetherapy of Cancer Using Recombinant Adenovirus Expressing Type III interferon IL-28A or IL-29

H. Arai, M. Tagawa, H. Tsukamoto, 2016 .

Oncolytic virotherapy for osteosarcoma using midkine promoter-regulated adenoviruses

T. Yamano, M. Tagawa, S. Kubo, 2014, Cancer Gene Therapy.

Enhanced antitumor efficacy of fiber‐modified, midkine promoter‐regulated oncolytic adenovirus in human malignant mesothelioma

T. Yamano, H. Okamura, M. Tagawa, 2013, Cancer science.

Murine colon carcinoma cells engineered to produce human interleukin‐2 induce tumor‐specific anti‐tumor response

F. Kondo, Yohko Nakamura, H. Matsubara, 1996, International journal of cancer.

Murine Fibrosarcoma IL-28 Elicits Antitumor Responses against Iwakura

Takashi Suzuki, M. Tagawa, Y. Iwakura, 2007 .

The secreted form of the p40 subunit of interleukin (IL)‐12 inhibits IL‐23 functions and abrogates IL‐23‐mediated antitumour effects

Hiroshi Yamamoto, M. Tagawa, A. Wada, 2006, Immunology.

Isolation and characterization of the gene for the murine T cell differentiation antigen and immunoglobulin-related molecule, Lyt-2.

G. Nolan, H. Nakauchi, L. Herzenberg, 1987, Nucleic acids research.

Fas Ligand DNA Enhances a Vaccination Effect by Coadministered DNA Encoding a Tumor Antigen through Augmenting Production of Antibody against the Tumor Antigen

M. Shingyoji, M. Tagawa, H. Shimada, 2015, Journal of immunology research.

Genomic DNA with transformation-related activity and melanoma antigen expression.

H. Matsubara, K. Shigemoto, T. Ito, 1989, Journal of Investigative Dermatology.

Method of Genomic DNA Cloning by the Combination of Cosmid Shuttle Vector and Monoclonal Antibody

H. Matsubara, M. Tagawa, Toshihiro Ito, 1988, Microbiology and immunology.

Isolation of Genomic DNA Controlling Mouse Melanoma Antigen Defined by Monoclonal Antibody

H. Matsubara, K. Shigemoto, M. Tagawa, 1988, Japanese journal of cancer research : Gann.

The effects of FasL on inflammation and tumor survival are dependent on its expression levels

M. Tagawa, T. Kuriyama, K. Tatsumi, 2007, Cancer Gene Therapy.

282. Effects of Fas Ligand on Inflammation and Tumor Survival Are Dependent on Its Expression Levels

M. Tagawa, T. Kuriyama, K. Tatsumi, 2005 .

Administration of DNA Encoding the Interleukin‐27 Gene Augments Antitumour Responses through Non‐adaptive Immunity

M. Shingyoji, M. Tagawa, H. Shimada, 2015, Scandinavian journal of immunology.

Recent advances in esophageal cancer gene therapy.

M. Tagawa, H. Shimada, K. Matsushita, 2008, Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia.

A Tumor-targeting Adenovirus with High Gene-transduction Efficiency for Primary Pancreatic Cancer and Ascites Cells.

N. Hiraoka, M. Tagawa, K. Aoki, 2017, Anticancer research.

Antitumor effect induced by the expression of granulocyte macrophage-colony stimulating factor gene in murine colon carcinoma cells.

H. Matsubara, M. Tagawa, S. Sakiyama, 1996, Cancer letters.

Cutting Edge: A Novel Role for Fas Ligand in Facilitating Antigen Acquisition by Dendritic Cells1

M. Tagawa, S. Sakiyama, T. Kuriyama, 2002, The Journal of Immunology.

Facilitating Antigen Acquisition by Dendritic Cutting Edge: A Novel Role for Fas Ligand in

M. Tagawa, S. Sakiyama, T. Kuriyama, 2002 .

Vaccination of apoptotic Fas ligand-expressing tumors decreased antitumor responses by enhanced production of immunosuppressive cytokines.

M. Tagawa, T. Kuriyama, K. Tatsumi, 2005, Anticancer research.

Fiber-substituted conditionally replicating adenovirus Ad5F35 induces oncolysis of human bladder cancer cells in in vitro analysis.

A. Gotoh, M. Tagawa, T. Nishizaki, 2013, Urology.

Carrier cell-mediated delivery of a replication-competent adenovirus for cancer gene therapy.

K. Hamada, A. Gotoh, T. Shirakawa, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

Expression of CD40 ligand in CD40-positive murine tumors activates transcription of the interleukin-23 subunit genes and produces antitumor responses.

M. Tagawa, T. Kuriyama, K. Tatsumi, 2004, Anticancer research.

Cytokine therapy for cancer.

M. Tagawa, 2000, Current pharmaceutical design.

Properties of Mouse Melanoma Antigen and Its Secretion Mechanism from the Cell Surface

M. Tagawa, Toshihiro Ito, M. Taniguchi, 1989, Japanese journal of cancer research : Gann.

Zoledronic acid induces apoptosis and S-phase arrest in mesothelioma through inhibiting Rab family proteins and topoisomerase II actions

Y. Jiang, M. Shingyoji, M. Tagawa, 2014, Cell Death and Disease.

Midkine Promoter Can Mediate Transcriptional Activation of a Fused Suicide Gene in a Broader Range of Human Breast Cancer Compared with c-erbB-2 Promoter

M. Tagawa, S. Sakiyama, T. Muramatsu, 2004, Oncology.

A minimum c-erbB-2 promoter-mediated expression of herpes simplex virus thymidine kinase gene confers selective cytotoxicity of human breast cancer cells to ganciclovir

H. Matsubara, M. Tagawa, S. Sakiyama, 2001, Cancer Gene Therapy.

Electroporation-mediated transfer of cytokine genes into human esophageal tumors produces anti-tumor effects in mice.

H. Matsubara, M. Tagawa, S. Sakiyama, 2001, Anticancer research.

Formal proof that different-size Lyt-2 polypeptides arise from differential splicing and post-transcriptional regulation.

G. Nolan, H. Nakauchi, L. Herzenberg, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Heat shock protein 90 inhibitors augment endogenous wild-type p53 expression but down-regulate the adenovirally-induced expression by inhibiting a proteasome activity

M. Shingyoji, M. Tagawa, H. Shimada, 2018, Oncotarget.

Human Monoclonal Antibody Detects a Cell Surface Antigen Expressed on Hematopoietic Malignant Cells of Lymphoid Lineage

Y. Matsuo, M. Tagawa, T. Iizasa, 1991, Japanese journal of cancer research : Gann.

NY-ESO-1 autoantibody as a tumor-specific biomarker for esophageal cancer: screening in 1969 patients with various cancers

M. Tagawa, H. Shimada, K. Matsushita, 2015, Journal of Gastroenterology.

Adenovirus vectors with chimeric type 5 and 35 fiber proteins exhibit enhanced transfection of human pancreatic cancer cells.

T. Masui, D. Ito, K. Kami, 2008, International journal of oncology.

Clinical significance of serum autoantibodies against Ras-like GTPases, RalA, in patients with esophageal squamous cell carcinoma

M. Tagawa, H. Shimada, K. Matsushita, 2016, Esophagus.

Efficacy of the bystander effect in the herpes simplex virus thymidine kinase-mediated gene therapy is influenced by the expression of connexin43 in the target cells

Y. Iwadate, M. Tagawa, H. Namba, 2001, Cancer Gene Therapy.

Syngeneic monoclonal antimelanoma antibodies and their application for analysis of tumor antigens, gene cloning, and in vitro/in vivo diagnosis.

M. Tagawa, M. Taniguchi, S. Wakabayashi, 1989, Pigment cell research.

Effects of neuropeptides on human lung and breast cancer cells.

P. Bunn, M. Tagawa, P. Jewett, 1992, Journal of the National Cancer Institute. Monographs.

Transduction of murine colon carcinoma cells with interleukin-15 gene induces antitumor effects in immunocompetent and immunocompromised hosts

M. Tagawa, K. Takenaga, T. Ochiai, 2000, Cancer Gene Therapy.

The Impact of Extracellular Low pH on the Anti-Tumor Efficacy Against Mesothelioma

M. Tagawa, H. Kobayashi, T. Fukamachi, 2012 .

Induction of acquired immunity in rats that have eliminated intracranial gliosarcoma cells by the expression of herpes simplex virus-thymidine kinase gene and ganciclovir administration.

Y. Iwadate, M. Tagawa, H. Namba, 1997, Oncology.

Bystander effect-mediated therapy of experimental brain tumor by genetically engineered tumor cells.

Y. Iwadate, M. Tagawa, H. Namba, 1998, Human gene therapy.

Enhanced expression of the β4-galactosyltransferase 2 gene impairs mammalian tumor growth

K. Kato, H. Mizuguchi, M. Tagawa, 2014, Cancer Gene Therapy.

Interleukin-12-mediated induction of systemic immunity in the periphery and recruitment of activated T cells into the brain produce limited antitumor effects compared with interleukin-2.

Y. Iwadate, M. Tagawa, H. Namba, 2002, International journal of molecular medicine.

Immunological responsiveness to interleukin-2-producing brain tumors can be restored by concurrent subcutaneous transplantation of the same tumors

Y. Iwadate, M. Tagawa, H. Namba, 2000, Cancer Gene Therapy.

Transduction of the human deoxycytidine kinase gene in rodent tumor cells induces in vivo growth retardation in syngeneic hosts.

M. Tagawa, H. Namba, S. Sakiyama, 2000, Cancer letters.

Treatment of rat experimental brain tumors by herpes simplex virus thymidine kinase gene-transduced allogeneic tumor cells and ganciclovir

Y. Iwadate, M. Tagawa, H. Namba, 2000, Cancer Gene Therapy.

Therapeutic efficacy of the suicide gene driven by the promoter of vascular endothelial growth factor gene against hypoxic tumor cells.

M. Tagawa, S. Sakiyama, K. Takenaga, 2000, Cancer research.

Hypoxic Tumor Cells Promoter of Vascular Endothelial Growth Factor Gene against Therapeutic Efficacy of the Suicide Gene Driven by the Updated

M. Tagawa, S. Sakiyama, K. Takenaga, 2000 .

Evaluation of the bystander effect in experimental brain tumors bearing herpes simplex virus-thymidine kinase gene by serial magnetic resonance imaging.

Y. Iwadate, M. Tagawa, H. Namba, 1996, Human gene therapy.

Midkine promoter-driven suicide gene expression and -mediated adenovirus replication produced cytotoxic effects to immortalised and tumour cells.

K. Hamada, M. Tagawa, M. Namba, 2004, European journal of cancer.

Utilization of the promoter region of the midkine gene as a tool to drive therapeutic genes in a tumor specific manner.

A. Nakagawara, M. Tagawa, S. Sakiyama, 2003, Advances in enzyme regulation.

Tissue-specific expression of a suicide gene for selective killing of neuroblastoma cells using a promoter region of the NCX gene

M. Hatano, M. Tagawa, S. Sakiyama, 2001, Cancer Gene Therapy.

Midkine promoter-based conditionally replicative adenovirus for targeting midkine-expressing human bladder cancer model.

K. Hamada, A. Gotoh, T. Shirakawa, 2007, Urology.

Genetic analysis reveals an intrinsic property of the germinal center B cells to generate A:T mutations.

J. Vijg, M. Dollé, F. Hanaoka, 2008, DNA repair.

DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes.

M. Tagawa, T. Tokuhisa, H. Koseki, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Expression of activation-induced cytidine deaminase is associated with a poor prognosis of diffuse large B cell lymphoma patients treated with CHOP-based chemotherapy

M. Tagawa, H. Shimada, K. Hiroshima, 2015, Journal of Cancer Research and Clinical Oncology.

DNA polymerase θ is preferentially expressed in lymphoid tissues and upregulated in human cancers

M. Hatano, M. Tagawa, S. Sakiyama, 2004, International journal of cancer.

Gene medicine for cancer treatment: Commercially available medicine and accumulated clinical data in China

M. Tagawa, H. Shimada, N. Suzuki, 2008, Drug design, development and therapy.

Melanoma Antigen and Transforming Gene

H. Matsubara, M. Tagawa, M. Taniguchi, 1988 .

Antitumor activity and immune enhancement of murine interleukin-23 expressed in murine colon carcinoma cells.

M. Tagawa, B. Shan, Qiao-xia Li, 2006, Cellular & molecular immunology.

Midkine promoter-based conditionally replicative adenovirus for malignant glioma therapy.

K. Hamada, M. Tagawa, K. Hashimoto, 2004, Oncology reports.

Correlation of the mutation of p53 gene and the polymorphism at codon 72 in smoking-related non-small cell lung cancer patients.

H. Shirasawa, M. Tagawa, T. Fujisawa, 1998, International journal of oncology.

Efficient antitumor effects of carrier cells loaded with a fiber-substituted conditionally replicating adenovirus on CAR-negative tumor cells

H. Mizuguchi, M. Tagawa, M. Kawabata, 2011, Cancer Gene Therapy.

Cytotoxicity of replication-competent adenoviruses powered by an exogenous regulatory region is not linearly correlated with the viral infectivity/gene expression or with the E1A-activating ability but is associated with the p53 genotypes

M. Shingyoji, M. Tagawa, H. Shimada, 2017, BMC Cancer.

Transcriptional regulatory regions of the survivin gene activate an exogenous suicide gene in human tumors and enhance the sensitivity to a prodrug.

M. Tagawa, M. Tomizawa, Quanhai Li, 2007, Anticancer research.

A Cox-2 Promoter-Based Replication-Selective Adenoviral Vector to Target the Cox-2-Expressing Human Bladder Cancer Cells

K. Hamada, A. Gotoh, T. Shirakawa, 2004, Clinical Cancer Research.

Metformin produces growth inhibitory effects in combination with nutlin-3a on malignant mesothelioma through a cross-talk between mTOR and p53 pathways

Hideaki Shimada, Koichiro Tatsumi, Yuji Tada, 2017, BMC Cancer.

Expression of acidosis-dependent genes in human cancer nests.

Hiroshi Kobayashi, M. Tagawa, T. Fukamachi, 2014, Molecular and clinical oncology.

Strong antitumor efficacy of a pancreatic tumor‐targeting oncolytic adenovirus for neuroendocrine tumors

S. Yachida, N. Hiraoka, R. Ohki, 2017, Cancer medicine.

M. Shingyoji, M. Tagawa, H. Shimada, 2015, Apoptosis.

Regulatory regions of growth-related genes can activate an exogenous gene of the alpha-fetoprotein promoter to a comparable degree in human hepatocellular carcinoma cells.

M. Tagawa, M. Tomizawa, H. Saisho, 2003, Anticancer research.

Increased infectivity of adenovirus type 5 bearing type 11 or type 35 fibers to human esophageal and oral carcinoma cells.

N. Seki, M. Tagawa, Y. Nimura, 2005, Oncology reports.

Identification of the human IAI.3B promoter element and its use in the construction of a replication-selective adenovirus for ovarian cancer therapy.

Y. Shirakata, K. Hamada, M. Tagawa, 2003, Cancer research.

Loss of tumorigenicity of human pancreatic carcinoma cells engineered to produce interleukin-2 or interleukin-4 in nude mice: a potentiality for cancer gene therapy.

F. Kondo, A. Nakagawara, M. Tagawa, 1998, Cancer letters.

Impaired in vivo tumor growth of human pancreatic carcinoma cells retrovirally transduced with GM-CSF gene.

M. Tagawa, S. Sakiyama, H. Saisho, 1998, Anticancer research.

Antitumor effect of human pancreatic cancer cells transduced with cytokine genes which activate Th1 helper T cells.

H. Yamamoto, M. Tagawa, S. Sakiyama, 1998, Anticancer research.

Polyadenylation signal facilitates the expression of foreign gene that is driven by an internal promoter located in the reverse orientation to long terminal repeat of retrovirus.

M. Tagawa, S. Sakiyama, H. Hamada, 2000, Anticancer research.

Suppressor T-Cell Hybridoma with a Receptor Recognizing KLH-Specific Suppressor Factor

T. Sumida, M. Tagawa, Toshihiro Ito, 1984 .

Growth Retardation, Polyploidy, and Multinucleation Induced by Clast3, a Novel Cell Cycle-regulated Protein*

Seiji Okada, Takeshi Tokuhisa, Jiyang O-Wang, 2002, The Journal of Biological Chemistry.

Role of Membrane Cholesterol Levels in Activation of Lyn upon Cell Detachment

M. Tagawa, Y. Nakayama, N. Yamaguchi, 2018, International journal of molecular sciences.

Clast5/Stra13 is a negative regulator of B lymphocyte activation.

Seiji Okada, Takeshi Tokuhisa, Yuji Tada, 2002, Biochemical and biophysical research communications.

A lysosomal protein negatively regulates surface T cell antigen receptor expression by promoting CD3zeta-chain degradation.

M. Hatano, M. Tagawa, T. Kurosaki, 2008, Immunity.

Novel type III interferons produce anti-tumor effects through multiple functions.

M. Tagawa, H. Shimada, K. Hiroshima, 2013, Frontiers in bioscience.

Interferon-lambda induces G1 phase arrest or apoptosis in oesophageal carcinoma cells and produces anti-tumour effects in combination with anti-cancer agents.

M. Tagawa, H. Shimada, N. Suzuki, 2010, European journal of cancer.

Impaired tumorigenicity and decreased liver metastasis of murine neuroblastoma cells engineered to secrete interleukin-2 or granulocyte macrophage colony-stimulating factor.

A. Nakagawara, M. Tagawa, S. Sakiyama, 1998, Cancer gene therapy.

A clinical protocol to inhibit the HGF/c-Met pathway for malignant mesothelioma with an intrapleural injection of adenoviruses expressing the NK4 gene

Kunio Matsumoto, Hideaki Shimada, Koichiro Tatsumi, 2015, SpringerPlus.

Stage-specific expression of Clast6/E3/LAPTM5 during B cell differentiation: elevated expression in human B lymphomas.

M. Tagawa, H. Saisho, M. Seimiya, 2003, International journal of oncology.

Analysis of a germ line polymorphism of the p53 gene in lung cancer patients; discrete results with smoking history.

M. Tagawa, H. Saisho, H. Kimura, 1996, Carcinogenesis.

Role of DNA polymerase theta in tolerance of endogenous and exogenous DNA damage in mouse B cells.

K. Kinoshita, M. Tagawa, T. Tokuhisa, 2006, Genes to cells : devoted to molecular & cellular mechanisms.

Role of DNA polymerase θ in tolerance of endogenous and exogenous DNA damage in mouse B cells

K. Kinoshita, M. Tagawa, T. Tokuhisa, 2005 .

Erratum to: NY-ESO-1 autoantibody as a tumor-specific biomarker for esophageal cancer: screening in 1969 patients with various cancers

M. Tagawa, H. Shimada, K. Matsushita, 2015, Journal of Gastroenterology.

Multi-panel assay of serum autoantibodies in colorectal cancer

M. Tagawa, Y. Nabeya, H. Shimada, 2018, International Journal of Clinical Oncology.

Panel of autoantibodies against multiple tumor‐associated antigens for detecting gastric cancer

M. Tagawa, Y. Nabeya, K. Matsushita, 2017, Cancer science.

Up-regulation of the error-prone DNA polymerase {kappa} promotes pleiotropic genetic alterations and tumorigenesis.

S. D. Pena, T. Helleday, M. Poupon, 2005, Cancer research.

DNA polymerase kappa, implicated in spontaneous and DNA damage-induced mutagenesis, is overexpressed in lung cancer.

M. Tagawa, S. Sakiyama, H. Ohmori, 2001, Cancer research.

Augmentation of in vivo growth of Lewis lung carcinoma cells transduced with granulocyte macrophage-colony stimulating factor gene.

M. Tagawa, S. Sakiyama, K. Takenaga, 1996, Cancer letters.

Heat-shock protein 90 inhibitors synergistically enhance melanoma differentiation-associated gene-7-mediated cell killing of human pancreatic carcinoma

Y. Jiang, M. Shingyoji, S. Chada, 2013, Cancer Gene Therapy.

Establishment of human monoclonal antibody recognizing a new tumor-associated antigen from a patient with small cell lung carcinoma.

M. Tagawa, T. Iizasa, T. Fujisawa, 1990, Hybridoma.

Expression of the Mig (CXCL9) gene in murine lung carcinoma cells generated angiogenesis-independent antitumor effects.

M. Tagawa, A. Wada, Yanqing Wang, 2003, Oncology reports.

[Enhanced expression of CD40L cDNA on ovarian cancer cell line OVHM induces the secretion of Th1 cytokines from dendritic cells].

M. Tagawa, Zheng-mao Zhang, Jie Liu, 2008, Zhonghua zhong liu za zhi [Chinese journal of oncology].

A promoter region of midkine gene can activate transcription of an exogenous suicide gene in human pancreatic cancer.

M. Tagawa, S. Sakiyama, M. Tomizawa, 2002, Anticancer Research.

In vivo and in vitro phosphorylation of murine lymphocyte differentiation antigen CD5.

H. Schulman, M. Tagawa, Leslie C. Griffith, 1989, Biochemical and biophysical research communications.

Genotype Difference of Aldehyde Dehydrogenase 2 Gene in Alcohol Drinkers Influences the Incidence of Japanese Colorectal Cancer Patients

M. Tagawa, T. Takeshita, K. Morimoto, 1999, Japanese journal of cancer research : Gann.

Irradiation with ultrasound of low output intensity increased chemosensitivity of subcutaneous solid tumors to an anti-cancer agent.

M. Ebara, M. Tagawa, S. Sakiyama, 2001, Cancer letters.

Bystander effect in uracil phosphoribosyltransferase/5-fluorouracil-mediated suicide gene therapy is correlated with the level of intercellular communication.

M. Tagawa, H. Namba, S. Sakiyama, 2001, International journal of oncology.

An essential role for REV3 in mammalian cell survival: absence of REV3 induces p53-independent embryonic death.

K. Kajiwara, M. Kimura, M. Tagawa, 2002, Biochemical and biophysical research communications.

Expression of the fetal-oncogenic fibroblast growth factor-8/17/18 subfamily in human hematopoietic tumors.

Y. Matsuo, T. Tomonaga, M. Tagawa, 2005, Biochemical and biophysical research communications.

IL-28 Elicits Antitumor Responses against Murine Fibrosarcoma

Takashi Suzuki, M. Tagawa, Y. Iwakura, 2007, The Journal of Immunology.

Dual-vector prodrug activator gene therapy using retroviral replicating vectors

M. Tagawa, N. Kasahara, S. Kubo, 2018, Cancer Gene Therapy.

Elevated expression of DNA polymerase kappa in human lung cancer is associated with p53 inactivation: Negative regulation of POLK promoter activity by p53.

A. Nakagawara, M. Tagawa, S. Sakiyama, 2004, International journal of oncology.

Binary expression of olfactory bulb-protein tyrosine phosphatase in rat central nervous system: developmental gene regulation in neonate cerebral cortex and constitutive expression in olfactory-rhinencephalon

M. Tagawa, T. Shirasawa, T. Tomoda, 1996, Neuroscience Letters.

Beneficial oncolytic effect of fiber-substituted conditionally replicating adenovirus on human lung cancer.

T. Nakano, A. Gotoh, M. Tagawa, 2012, Anticancer research.

Cancer Cell-specific Transfection of hCas9 Gene Using Ad5F35 Vector

K. Hamada, A. Gotoh, M. Tagawa, 2021, Anticancer Research.

Gene Expressions for Signal Transduction under Acidic Conditions

Hiroshi Kobayashi, M. Tagawa, Xin Wang, 2013, Genes.

Combination of a p53-activating CP-31398 and an MDM2 or a FAK inhibitor produces growth suppressive effects in mesothelioma with wild-type p53 genotype

M. Shingyoji, M. Tagawa, H. Shimada, 2020, Apoptosis.

Adenovirus type 5 substituted with type 11 or 35 fiber structure increases its infectivity to human cells enabling dual gene transfer in CD46-dependent and -independent manners.

M. Tagawa, M. Namba, Quanhai Li, 2007, Anticancer research.

Expression of p53 synergistically augments caspases-mediated apoptosis induced by replication-competent adenoviruses in pancreatic carcinoma cells

Y. Jiang, M. Shingyoji, M. Tagawa, 2015, Cancer Gene Therapy.

A combinatory use of adenoviruses expressing melanoma differentiation-associated gene-7 and replication-competent adenoviruses produces synergistic effects on pancreatic carcinoma cells

M. Shingyoji, M. Tagawa, H. Shimada, 2015, Tumor Biology.

Identification of a receptor-type protein tyrosine phosphatase expressed in postmitotic maturing neurons: its structure and expression in the central nervous system.

M. Tagawa, S. Sakiyama, T. Shirasawa, 1997, The Biochemical journal.

Tumor specific low pH environments enhance the cytotoxicity of lovastatin and cantharidin.

Hiroshi Kobayashi, M. Tagawa, T. Fukamachi, 2010, Cancer letters.

The p73 gene is not mutated in oligodendrogliomas which frequently have a deleted region at chromosome 1p36.3.

A. Nakagawara, Y. Iwadate, M. Tagawa, 2000, Anticancer Research.

Loss of tumorigenicity of human breast cancer cells engineered to produce IL-2, IL-4 or GM-CSF in nude mice.

H. Matsubara, M. Tagawa, S. Sakiyama, 1999, International journal of oncology.

Alteration of CDKN2/p16 in human astrocytic tumors is related with increased susceptibility to antimetabolite anticancer agents.

S. Fujimoto, Y. Iwadate, M. Tagawa, 2000, International journal of oncology.

Antitumor effect of chondroitin sulfate‐coated ternary granulocyte macrophage‐colony‐stimulating factor plasmid complex for ovarian cancer

K. Hamada, Tomoko Ito, M. Tagawa, 2012, The journal of gene medicine.

Augmented expression of cardiac ankyrin repeat protein is induced by pemetrexed and a possible marker for the pemetrexed resistance in mesothelioma cells

M. Shingyoji, M. Tagawa, N. Yamaguchi, 2017, Cancer Cell International.

Epitope-specific regulation. IV. In vitro studies with suppressor T cells induced by carrier/hapten-carrier immunization.

M. Tagawa, T. Tokuhisa, M. Taniguchi, 1984, Cellular immunology.

Induction of T cell dependent acquired immunity in syngeneic mice by the combined expression of interleukin-4 and granulocyte macrophage-colony stimulating factor gene in murine colon carcinoma cells.

H. Matsubara, M. Tagawa, S. Sakiyama, 1998, Anticancer research.

Identification of a minimal c-erbB-2 promoter region that mediates preferential expression of a linked foreign gene in human breast cancer cells.

M. Tagawa, Ling Yu, S. Kamo, 2002, International journal of oncology.

Midkine is a potential novel marker for malignant mesothelioma with different prognostic and diagnostic values from mesothelin

M. Metintaş, M. Tagawa, H. Shimada, 2017, BMC Cancer.

Transduction of the IL-21 and IL-23 genes in human pancreatic carcinoma cells produces natural killer cell-dependent and -independent antitumor effects

Hiroshi Yamamoto, M. Tagawa, S. Sakiyama, 2003, Cancer Gene Therapy.

M. Tagawa, H. Shimada, K. Matsushita, 2010, Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia.

Decreased expression of the CCAAT/enhancer binding protein alpha gene involved in hepatocyte proliferation in human hepatocellular carcinomas.

M. Ebara, A. Nakagawara, M. Tagawa, 2002, International journal of molecular medicine.

An image cytometric technique is a concise method to detect adenoviruses and host cell proteins and to monitor the infection and cellular responses induced

M. Shingyoji, M. Tagawa, H. Shimada, 2017, Virology Journal.

Combination of a p53-activating CP-31398 and an MDM2 or a FAK inhibitor produces growth suppressive effects in mesothelioma with wild-type p53 genotype

M. Shingyoji, M. Tagawa, H. Shimada, 2020, Apoptosis.

M. Tagawa, H. Shimada, K. Hiroshima, 2014, BMC Cancer.

Adenoviruses-mediated transduction of human oesophageal carcinoma cells with the interferon-λ genes produced anti-tumour effects

M. Tagawa, M. Namba, H. Shimada, 2011, British Journal of Cancer.

IL-28 Elicits Antitumor Responses against

Akira Nakamura, Setsuya Aiba, Masahiro Okada, 2013 .

A p53-stabilizing agent, CP-31398, induces p21 expression with increased G2/M phase through the YY1 transcription factor in esophageal carcinoma defective of the p53 pathway.