N. Khodarev

发表

Synchronous block in DNA synthesis initiation with change in chromatin topology mediated by VP16.

A. Narayana, N. Khodarev, S. Walter, 1998, DNA and cell biology.

Progression of Barrett's metaplasia to adenocarcinoma is associated with the suppression of the transcriptional programs of epidermal differentiation.

Masha Kocherginsky, John Hart, R. Weichselbaum, 2005, Cancer research.

Safety and Clinical Activity of Pembrolizumab and Multisite Stereotactic Body Radiotherapy in Patients With Advanced Solid Tumors.

Manish R. Sharma, M. Ratain, H. Al-Hallaq, 2018, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Tumour-endothelium interactions in co-culture: coordinated changes of gene expression profiles and phenotypic properties of endothelial cells

R. Weichselbaum, N. Khodarev, T. Darga, 2003, Journal of Cell Science.

RIG-I–like receptor LGP2 protects tumor cells from ionizing radiation

R. Weichselbaum, N. Khodarev, T. Darga, 2014, Proceedings of the National Academy of Sciences.

Diverse TNFα-induced death pathways are enhanced by inhibition of NF-κB

R. Weichselbaum, M. Posner, D. Kufe, 2007 .

Intracellular RNA Sensing in Mammalian Cells: Role in Stress Response and Cancer Therapies.

N. Khodarev, 2019, International review of cell and molecular biology.

Receiver operating characteristic analysis: a general tool for DNA array data filtration and performance estimation.

Samuel Hellman, Charles A Pelizzari, Bernard Roizman, 2003, Genomics.

Oncogenic CXCL10 signalling drives metastasis development and poor clinical outcome

R. Weichselbaum, M. Posner, N. Khodarev, 2015, British Journal of Cancer.

Association between DNA cleavage during apoptosis and regions of chromatin replication

N. Khodarev, A. Vaughan, I. Sokolova, 1998, Journal of cellular biochemistry.

Oligo- and Polymetastatic Progression in Lung Metastasis(es) Patients Is Associated with Specific MicroRNAs

Oleksiy Karpenko, R. Weichselbaum, Y. Lussier, 2012, PloS one.

The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity.

R. Weichselbaum, Youjin Lee, N. Khodarev, 2011, Cancer research.

DNA Methylation Controls Metastasis-Suppressive 14q32-Encoded miRNAs.

R. Weichselbaum, M. Posner, N. Khodarev, 2018, Cancer research.

Accumulation of specific RNAs encoding transcriptional factors and stress response proteins against a background of severe depletion of cellular RNAs in cells infected with herpes simplex virus 1.

N. Khodarev, S. Advani, B. Roizman, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Basal Tumor Cell Isolation and Patient-Derived Xenograft Engraftment Identify High-Risk Clinical Bladder Cancers

R. Weichselbaum, M. Posner, G. Steinberg, 2016, Scientific Reports.

Tumor Endothelial Inflammation Predicts Clinical Outcome in Diverse Human Cancers

Wei Zhang, Nikolai N. Khodarev, Ralph R. Weichselbaum, 2012, PloS one.

Molecular Pathways Molecular Pathways : Interferon / Stat 1 Pathway : Role in the Tumor Resistance to Genotoxic Stress and Aggressive Growth

R. Weichselbaum, N. Khodarev, B. Roizman, 2012 .

Quantitative analysis of DNA array autoradiographs.

C. Pelizzari, N. Khodarev, N. Gupta, 2000, Nucleic acids research.

Activation of the nuclear transcription factor κB (NFκB) and differential gene expression in U87 glioma cells after exposure to the cytoprotector amifostine

R. Weichselbaum, N. Khodarev, Y. Kataoka, 2002 .

Diverse TNFalpha-induced death pathways are enhanced by inhibition of NF-kappaB.

R. Weichselbaum, M. Posner, D. Kufe, 2007, International journal of oncology.

An inducible lymphocyte nuclear Ca2+/Mg(2+)-dependent endonuclease associated with apoptosis.

N. Khodarev, J. Ashwell, 1996, Journal of immunology.

Improved Survival Associated with Local Tumor Response Following Multisite Radiotherapy and Pembrolizumab: Secondary Analysis of a Phase I Trial

R. Weichselbaum, P. Ott, N. Khodarev, 2020, Clinical Cancer Research.

Topologically constrained domains of supercoiled DNA in eukaryotic cells.

A. Constantinou, A. Narayana, N. Khodarev, 1997, DNA and cell biology.

Glioblastoma cells block radiation‐induced programmed cell death of endothelial cells

R. Weichselbaum, M. Posner, N. Khodarev, 2004, FEBS letters.

Abortive apoptosis as an initiator of chromosomal translocations.

N. Khodarev, A. Vaughan, I. Sokolova, 1999, Medical hypotheses.

Author Correction: Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis

K. White, R. Weichselbaum, M. Talamonti, 2018, Nature Communications.

Mechanisms of induction of apoptotic DNA fragmentation.

N. Khodarev, A. Vaughan, I. Sokolova, 2009, International journal of radiation biology.

Early postirradiation chromatin degradation in thymocytes.

V. Soldatenkov, N. Khodarev, I. Filippovich, 1989, International journal of radiation biology.

Mycoplasma infection can sensitize host cells to apoptosis through contribution of apoptotic‐like endonuclease(s)

N. Khodarev, A. Vaughan, I. Sokolova, 1998, Immunology and cell biology.

Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis

Jorge Andrade, Sabha Ganai, Samuel Hellman, 2018, Nature Communications.

MicroRNA Expression Characterizes Oligometastasis(es)

R. Weichselbaum, Y. Lussier, X. Yang, 2011, PloS one.

An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer

Hemant Ishwaran, Taewon Yoon, Yudi Pawitan, 2008, Proceedings of the National Academy of Sciences.

MUC1-induced alterations in a lipid metabolic gene network predict response of human breast cancers to tamoxifen treatment

Donald W Kufe, R. Weichselbaum, D. Kufe, 2009, Proceedings of the National Academy of Sciences.

MUC1-induced transcriptional programs associated with tumorigenesis predict outcome in breast and lung cancer.

R. Weichselbaum, D. Kufe, N. Khodarev, 2009, Cancer research.

Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity

B. Shakhsheer, Jennifer R. Defazio, S. Christley, 2020, Nature Communications.

Expression Signature of IFN/STAT1 Signaling Genes Predicts Poor Survival Outcome in Glioblastoma Multiforme in a Subtype-Specific Manner

X. Cui, R. Weichselbaum, Tapan Mehta, 2012, PloS one.

Temozolomide Treatment Induces lncRNA MALAT1 in an NF-κB and p53 Codependent Manner in Glioblastoma.

Wei Zhang, R. Weichselbaum, N. Khodarev, 2019, Cancer research.

STING Promotes Homeostasis via Regulation of Cell Proliferation and Chromosomal Stability.

Michael J. Bolt, R. Weichselbaum, N. Khodarev, 2018, Cancer research.

JAK2 Inhibitor SAR302503 Abrogates PD-L1 Expression and Targets Therapy-Resistant Non–small Cell Lung Cancers

R. Weichselbaum, M. Posner, N. Khodarev, 2018, Molecular Cancer Therapeutics.

4-Hydroxyacetophenone modulates the actomyosin cytoskeleton to reduce metastasis

A. Pearson, R. Weichselbaum, M. Posner, 2020, Proceedings of the National Academy of Sciences.

CD95/Fas Increases Stemness in Cancer Cells by Inducing a STAT1-Dependent Type I Interferon Response.

M. Peter, Jindan Yu, R. Weichselbaum, 2017, Cell reports.

Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs

S. Akira, R. Weichselbaum, T. Satoh, 2016, Oncotarget.

Molecular Pathways Molecular Pathways : Interferon / Stat 1 Pathway : Role in the Tumor Resistance to Genotoxic Stress and Aggressive Growth

R. Weichselbaum, N. Khodarev, B. Roizman, 2012 .

In Vivo Delivery and Therapeutic Effects of a MicroRNA on Colorectal Liver Metastases.

R. Weichselbaum, M. Posner, N. Khodarev, 2017, Molecular therapy : the journal of the American Society of Gene Therapy.

Towards a molecular basis of oligometastatic disease: potential role of micro-RNAs

R. Weichselbaum, M. Posner, N. Khodarev, 2014, Clinical & Experimental Metastasis.

14q32-encoded microRNAs mediate an oligometastatic phenotype

R. Weichselbaum, M. Posner, N. Khodarev, 2015, Oncotarget.

Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling

R. Weichselbaum, N. Khodarev, T. Darga, 2009, International journal of radiation biology.

Clinical and molecular markers of long‐term survival after oligometastasis‐directed stereotactic body radiotherapy (SBRT)

R. Weichselbaum, N. Khodarev, A. Wong, 2016, Cancer.

STAT1 Pathway Mediates Amplification of Metastatic Potential and Resistance to Therapy

R. Weichselbaum, M. Posner, N. Khodarev, 2009, PloS one.

Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells.

Bernard Roizman, R. Weichselbaum, A. Minn, 2007, Cancer research.

Evidence for the Use of Multiple Mechanisms by Herpes Simplex Virus-1 R7020 to Inhibit Intimal Hyperplasia

R. Weichselbaum, N. Khodarev, J. Stern, 2015, PloS one.

Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity

B. Shakhsheer, Jennifer R. Defazio, S. Christley, 2020, Nature Communications.

Ad.Egr-TNF and local ionizing radiation suppress metastases by interferon-beta-dependent activation of antigen-specific CD8+ T cells.

R. Weichselbaum, D. Kufe, N. Khodarev, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

Ad.Egr-TNF and Local Ionizing Radiation Suppress Metastases by Interferon-β-Dependent Activation of Antigen-specific CD8+ T Cells.

R. Weichselbaum, D. Kufe, N. Khodarev, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

Interaction of amifostine and ionizing radiation on transcriptional patterns of apoptotic genes expressed in human microvascular endothelial cells (HMEC).

R. Weichselbaum, N. Khodarev, Y. Kataoka, 2004, International journal of radiation oncology, biology, physics.

MUC1-associated proliferation signature predicts outcomes in lung adenocarcinoma patients

C. Pelizzari, R. Weichselbaum, D. Edwards, 2010, BMC Medical Genomics.

COOPERATIVITY OF THE MUC1 ONCOPROTEIN AND STAT1 PATHWAY IN POOR PROGNOSIS HUMAN BREAST CANCER

R. Weichselbaum, D. Kufe, N. Khodarev, 2009, Oncogene.

Activation of the nuclear transcription factor kappaB (NFkappaB) and differential gene expression in U87 glioma cells after exposure to the cytoprotector amifostine.

R. Weichselbaum, N. Khodarev, Y. Kataoka, 2002, International journal of radiation oncology, biology, physics.

STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells.

Bernard Roizman, R. Weichselbaum, N. Khodarev, 2004, Proceedings of the National Academy of Sciences of the United States of America.

STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect

R. Weichselbaum, N. Khodarev, M. Beckett, 2009, BMC medicine.

Tumor Cells Regulates Both Cytotoxic and Prosurvival Functions in Signal Transducer and Activator of Transcription 1

R. Weichselbaum, A. Minn, N. Khodarev, 2007 .

Translational strategies exploiting TNF-α that sensitize tumors to radiation therapy

R. Weichselbaum, M. Posner, D. Kufe, 2009, Cancer Gene Therapy.

Progression of cancer from indolent to aggressive despite antigen retention and increased expression of interferon-gamma inducible genes.

R. Weichselbaum, N. Khodarev, H. Schreiber, 2011, Cancer immunity.

Internucleosomal chromatin degradation in myeloma and B‐hybridoma cell cultures

N. Khodarev, V. Volgina, N. Makarova, 1992, FEBS Letters.

Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts

R. Weichselbaum, N. Khodarev, B. Roizman, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Isolation of Ca, Mg-dependent nuclear endonuclease as a principal component of the nuclease complex of human lymphocyte chromatin

N. Khodarev, S. Aleksandrova, V. Volgina, 1987, Bulletin of Experimental Biology and Medicine.

Tumor-reprogrammed resident T cells resist radiation to control tumors

R. Weichselbaum, Yuzhu Hou, I. Lowy, 2019, Nature Communications.

Systemic miRNA delivery by nontoxic nanoscale coordination polymers limits epithelial-to-mesenchymal transition and suppresses liver metastases of colorectal cancer.

R. Weichselbaum, N. Khodarev, Wenbin Lin, 2019, Biomaterials.

Integrated molecular subtyping defines a curable oligometastatic state in colorectal liver metastasis

K. White, R. Weichselbaum, M. Talamonti, 2018, Nature Communications.

Towards a molecular basis of oligometastatic disease: potential role of micro-RNAs

R. Weichselbaum, M. Posner, N. Khodarev, 2014, Clinical & Experimental Metastasis.

Imaging of tumor clones with differential liver colonization

R. Weichselbaum, M. Posner, N. Khodarev, 2015, Scientific Reports.

Intermolecular homologies of human interferon-alpha.

N. Khodarev, I. I. Votrin, F. Romantsev, 1992, Biochemical and biophysical research communications.

MUC 1-Associated Proliferation Signature Predicts Outcomes in Lung Adenocarcinoma Patients

C. Pelizzari, R. Weichselbaum, D. Edwards, 2010 .

Method of RNA purification from endothelial cells for DNA array experiments.

N. Khodarev, Y. Kataoka, C. K. Brown, 2002, BioTechniques.

Angiostatin effects on endothelial cells mediated by ceramide and RhoA

R. Weichselbaum, D. Kufe, N. Khodarev, 2001, EMBO reports.

Supplemental Information CD 95 / Fas Increases Stemness in Cancer Cells by Inducing a STAT 1-Dependent Type I Interferon Response

M. Peter, N. Khodarev, Abdul S. Qadir, 2017 .

Computer analysis of data on chromatin fragmentation by nucleases

N. Khodarev, A. Sokolov, I. Sokolova, 2004, Bulletin of Experimental Biology and Medicine.

Fecal microbiota transplant rescues mice from sepsis due to multi-drug resistant healthcare pathogens by restoring systemic immunity

B. Shakhsheer, Jennifer R. Defazio, S. Christley, 2021 .

Comparative study of Ca,Mg-dependent endonuclease in cell nuclei by the use of monoclonal antibodies

N. Khodarev, V. Volgina, L. A. Pevnitskii, 1988, Bulletin of Experimental Biology and Medicine.

Endothelial cells co‐cultured with wild‐type and dominant/negative p53‐transfected glioblastoma cells exhibit differential sensitivity to radiation‐induced apoptosis

R. Weichselbaum, N. Khodarev, T. Darga, 2004, International journal of cancer.

Programs of Epidermal Differentiation Associated with the Suppression of the Transcriptional Progression of Barrett ' s Metaplasia to Adenocarcinoma Is

R. Weichselbaum, J. Mezhir, M. Posner, 2005 .

14q32-encoded microRNAs mediate an oligometastatic phenotype

R. Weichselbaum, M. Posner, N. Khodarev, 2015, Oncotarget.

STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect

R. Weichselbaum, N. Khodarev, M. Beckett, 2009 .

Correction: Oligo- and Polymetastatic Progression in Lung Metastasis(es) Patients Is Associated with Specific MicroRNAs

Oleksiy Karpenko, R. Weichselbaum, Y. Lussier, 2013, PLoS ONE.

14q32-encoded microRNAs mediate an oligometastatic phenotype

N. Khodarev, T. Darga, Lei Huang, 2015, Oncotarget.

[Ca/Mg-dependent endonuclease as a probe for detecting chromatin changes in lymphocytes in chronic lymphoid leukemia].

N. Khodarev, S. Aleksandrova, I. Sokolova, 1987, Molekuliarnaia genetika, mikrobiologiia i virusologiia.

Pseudomonas aeruginosa wound infection involves activation of its iron acquisition system in response to fascial contact

S. Christley, Irma D. Fleming, O. Zaborina, 2015, The journal of trauma and acute care surgery.

[Characteristics of the degradation of thymus lymphocyte DNA in the early periods after irradiation].

V. Soldatenkov, N. Khodarev, I. Filippovich, 1989, Radiobiologiia.

Systemic miRNA delivery by nontoxic nanoscale coordination polymers limits epithelial-to-mesenchymal transition and suppresses liver metastases of colorectal cancer.

R. Weichselbaum, N. Khodarev, Wenbin Lin, 2019, Biomaterials.

LINE L1 retrotransposable element is targeted during the initial stages of apoptotic DNA fragmentation

N. Khodarev, S. Walter, A. Vaughan, 2000, Journal of cellular biochemistry.

STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect

N. Khodarev, S. Pitroda, D. Macdermed, 2009, BMC medicine.