C. Ireland

发表

Multiple centrosomal microtubule organising centres and increased microtubule stability are early features of VP-16-induced apoptosis in CCRF-CEM cells.

M. Fraser, S. Pittman, M. Geyp, 1997, Leukemia research.

Increased tubulin acetylation accompanies reversion to stable ploidy in vincristine-resistant CCRF-CEM cells.

S. Pittman, M. Geyp, C. Ireland, 1996, Cancer genetics and cytogenetics.

Topsentinol L Trisulfate, a new Marine Natural Product, that Targets Basal-like and Claudin-low Breast Cancers

Stephen R. Piccolo, M. K. Harper, Thomas E. Smith, 2020, bioRxiv.

Bengacarboline, a New β-Carboline from a Marine Ascidian Didemnum sp.

P. Lassota, C. Ireland, T. Foderaro, 1997 .

Marine-derived fungi: a chemically and biologically diverse group of microorganisms.

C. Ireland, T. Bugni, 2004, Natural product reports.

WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

M. K. Harper, I. Mihalek, C. Ireland, 2010, Journal of Cell Science.

The interaction of benzimidazole carbamates with mammalian microtobule protein.

K. Gull, C. Ireland, C. I. Pogson, 1979, Biochemical pharmacology.

Absolute configuration of thiazole amino acids in peptides

C. Ireland, J. Biskupiak, 1983 .

Studies on the solution- and solid-state structure of patellin 2

J. Clardy, M. Foster, C. Ireland, 1990 .

Patellamide E: a new cyclic peptide from the ascidian Lissoclinum patella.

C. Ireland, L. McDonald, 1992, Journal of natural products.

Tawicyclamides A and B, new cyclic peptides from the Ascidian Lissoclinum patella: studies on the solution- and solid-state conformations

J. Clardy, M. Foster, C. Ireland, 1992 .

Benzotriazoles Reactivate Latent HIV-1 through Inactivation of STAT5 SUMOylation

A. Spivak, D. Margolis, N. Archin, 2017, Cell reports.

Isolation and characterization of 1,3-dimethylisoguanine from the Bermudian sponge Amphimedon viridis.

C. Ireland, H. Trapido-Rosenthal, S. Mitchell, 1997, Journal of natural products.

Lissoclinotoxins E and F, novel cytotoxic alkaloids from a Philippine didemnid ascidian

C. Ireland, G. Concepcion, R. Rocha, 2003 .

Natural Product Peptides from Marine Organisms

M. Foster, C. Ireland, T. Molinski, 1989 .

A study on the mechanism of action of sceptrin, an antimicrobial agent isolated from the South Pacific sponge Agelas mauritiana.

C. Ireland, D. A. Steinberg, M. Greenstein, 1993, The Journal of antimicrobial chemotherapy.

Jaspamide, a modified peptide from a Jaspis sponge, with insecticidal and antifungal activity.

J. Clardy, C. Ireland, T. Molinski, 1986 .

Bioactive isomalabaricane triterpenes from the marine sponge Rhabdastrella globostellata.

M. K. Harper, C. Ireland, S. Rabindran, 2002, Journal of natural products.

Novel cytotoxic topoisomerase II inhibiting pyrroloiminoquinones from Fijian sponges of the genus Zyzzya

D. Radisky, C. Ireland, E. Radisky, 1993 .

Makaluvamine N: a new pyrroloiminoquinone from Zyzzya fuliginosa.

C. Ireland, L. Barrows, G. Concepcion, 1997, Journal of natural products.

3,7-Dimethylguanine, a new purine from a Philippine sponge Zyzzya fuliginosa.

M. K. Harper, C. Ireland, D. Taşdemir, 2001, Chemical & pharmaceutical bulletin.

Wakayin: A novel cytotoxic pyrroloiminoquinone alkaloid from the ascidian Clavelina species

C. Ireland, L. Barrows, B. Copp, 1991 .

Fascaplysin, an unusual antimicrobial pigment from the marine sponge Fascaplysinopsis sp

J. Clardy, C. Ireland, Helen S. M. Lu, 1988 .

Cadiolides A and B, New Metabolites from an Ascidian of the Genus Botryllus

R. Hettich, C. Ireland, J. Jompa, 1998 .

Neoamphimedine: A New Pyridoacridine Topoisomerase II Inhibitor Which Catenates DNA

M. K. Harper, C. Ireland, L. Barrows, 1999 .

Challenge of large-scale motion for residual dipolar coupling based analysis of configuration: the case of fibrosterol sulfate A.

Edward J. d'Auvergne, A. Navarro‐Vázquez, C. Griesinger, 2011, Journal of the American Chemical Society.

Aurantosides G, H, and I: three new tetramic acid glycosides from a Papua New Guinea Theonella swinhoei.

M. K. Harper, C. Ireland, L. Barrows, 2005, Journal of natural products.

Theopapuamide, a cyclic depsipeptide from a Papua New Guinea lithistid sponge Theonella swinhoei.

M. K. Harper, C. Ireland, L. Barrows, 2006, Journal of natural products.

Juvenile Hormone Mimics: Effect on Cirriped Crustacean Metamorphosis

C. Ireland, E. Gomez, D. Faulkner, 1973, Science.

Tetrahdroxysqualene from Rhus taitensis shows antimycobacterial activity against Mycobacterium tuberculosis.

C. Ireland, L. Barrows, T. Bugni, 2008, Journal of natural products.

Punaglandins, chlorinated prostaglandins, function as potent Michael receptors to inhibit ubiquitin isopeptidase activity.

C. Ireland, F. Fitzpatrick, J. Mullally, 2004, Journal of medicinal chemistry.

A Central Strategy for Converting Natural Products into Fluorescent Probes

M. K. Harper, A. Richardson, C. Ireland, 2006, Chembiochem : a European journal of chemical biology.

Tedanolide C: a potent new 18-membered-ring cytotoxic macrolide isolated from the Papua New Guinea marine sponge Ircinia sp.

M. K. Harper, C. Ireland, T. Bugni, 2006, The Journal of organic chemistry.

Induction of apoptosis in peripheral blood lymphocytes following treatment in vitro with hydroxychloroquine.

J. Ziegler, S. Pittman, C. Ireland, 1997, Arthritis and rheumatism.

Studies in the metabolism of carcinogenic polycyclic heteroaromatic compounds. I. The hepatic microsomal metabolism of 7-methylbenz[c]acridine.

C. Ireland, G. Holder, A. J. Ryan, 1981, Biochemical pharmacology.

Patellins 1-6 and trunkamide A: Novel cyclic hexa-, hepta- and octa-peptides from colonial ascidians, Lissoclinum sp

A. Carroll, C. Ireland, J. Coll, 1996 .

Ulicyclamide and ulithiacyclamide, two new small peptides from a marine tunicate [8]

C. Ireland, P. Scheuer, 1980 .

New Tetromycin Derivatives with Anti-Trypanosomal and Protease Inhibitory Activities †

C. Ireland, G. Bringmann, U. Hentschel, 2011, Marine drugs.

Juxtaposition of chemical and mutation-induced developmental defects in zebrafish reveal a copper-chelating activity for kalihinol F.

D. Winge, E. Manos, David A Jones, 2013, Chemistry & biology.

Characterization and three-dimensional structure determination of psi-conotoxin Piiif, a novel noncompetitive antagonist of nicotinic acetylcholine receptors.

C. Ireland, R. V. van Wagoner, B. Olivera, 2003, Biochemistry.

An Improved Solution Structure for ψ-Conotoxin Piiie†,‡

C. Ireland, R. V. Wagoner, 2003 .

Three-dimensional solution structure of conotoxin psi-PIIIE, an acetylcholine gated ion channel antagonist.

M. Foster, C. Ireland, B. Olivera, 1998, Biochemistry.

Applications of the improved computerized analysis of 2D INADEQUATE spectra.

M. Foster, C. Ireland, D. Grant, 1992, Analytical chemistry.

Biologically active components of a Papua New Guinea analgesic and anti-inflammatory lichen preparation.

C. Ireland, L. Barrows, T. Bugni, 2009, Fitoterapia.

Inhibition of poly(ADP-ribose) synthesis may affect DNA repair prior to ligation.

B. Stewart, C. Ireland, 1987, Carcinogenesis.

Presence of serotonin in the venom of Conus imperialis.

C. Ireland, J. McIntosh, T. Foderaro, 1993, Toxicon : official journal of the International Society on Toxinology.

Bistratamides C and D. Two new oxazole-containing cyclic hexapeptides isolated from a Philippine Lissoclinum bistratum ascidian

M. Foster, C. Ireland, G. Concepcion, 1992 .

Evaluation of Pyridoacridine Alkaloids in a Zebrafish Phenotypic Assay

M. K. Harper, E. Manos, David A Jones, 2010, Marine drugs.

Lomaiviticins A and B, potent antitumor antibiotics from Micromonospora lomaivitiensis.

A. Richardson, C. Ireland, G. Carter, 2001, Journal of the American Chemical Society.

The complete spectral assignment of didemnin B and nordidemnin B

C. Ireland, N. Lindquist, W. Fenical, 1989 .

Anti-Parasitic Compounds from Streptomyces sp. Strains Isolated from Mediterranean Sponges

C. Ireland, U. Hentschel, T. Bugni, 2010, Marine drugs.

ULICYCLAMIDE AND ULITHIACYCLAMIDE, TWO NEW SMALL PEPTIDES FROM A MARINE TUNICATE

C. Ireland, P. Scheuer, 1980 .

Activated N-ras oncogenes in human neuroblastoma.

C. Ireland, Christine M. Ireland, 1989, Cancer research.

Comparative interactions of streptozotocin and chlorozotocin with DNA of an insulin-secreting cell line (RINr)

C. Ireland, S. Ledoux, B. Mossman, 1986, Diabetologia.

Penicillium dravuni, a new marine-derived species from an alga in Fiji

C. Ireland, T. Bugni, J. Janso, 2005 .

Two Ring-A-Aromatized Bile Acids from the Marine Sponge Sollasella Moretonensis

M. K. Harper, C. Ireland, R. V. van Wagoner, 2010, Natural product communications.

Distinct Pathways Generate Peptides from Defective Ribosomal Products for CD8+ T Cell Immunosurveillance

J. Yewdell, J. Bennink, C. Ireland, 2011, The Journal of Immunology.

Halogenated cyclic peptides isolated from the sponge Corticium sp.

M. K. Harper, C. Ireland, D. Laird, 2007, Journal of natural products.

Iodinated phenethylamine products from a didemnid tunicate

C. Ireland, D. F. Sesin, 1984 .

Psammaplin A as a general activator of cell-based signaling assays via HDAC inhibition and studies on some bromotyrosine derivatives.

M. K. Harper, C. Ireland, D. Virshup, 2009, Bioorganic & medicinal chemistry.

Brocaenols A-C: novel polyketides from a marine derived Penicillium brocae.

C. Ireland, T. Bugni, J. Janso, 2003, The Journal of organic chemistry.

Salinamides A and B: anti-inflammatory depsipeptides from a marine streptomycete

J. Clardy, C. Ireland, P. Jensen, 1994 .

Allele-specific enrichment: a method for the detection of low level N-ras gene mutations in acute myeloid leukemia.

C. Ireland, A. Todd, H. Iland, 1991, Leukemia.

Myristicyclins A and B: antimalarial procyanidins from Horsfieldia spicata from Papua New Guinea.

J. Jensen, C. Ireland, R. V. van Wagoner, 2014, Organic letters.

Plakinamine M, a steroidal alkaloid from the marine sponge Corticium sp.

M. K. Harper, C. Ireland, R. V. van Wagoner, 2013, Journal of natural products.

Iridoids and triterpene saponins from Verbascum wiedemannianum (Scrophulariaceae)

C. Ireland, İ. Çalış, D. Taşdemir, 2003 .

Phenylethanoid glycosides from Scutellaria galericulata

C. Ireland, İ. Çalış, D. Taşdemir, 2002 .

Ants remove virtually all western myall (Acacia papyrocarpa Benth.) seeds at Middleback, South Australia

C. Ireland, M. Andrew, 1995 .

DNA‐mediated gene transfer as an indicator of DNA damage and its repair by recipient cells

B. Stewart, C. Ireland, C. M. Ireland, 1987, FEBS letters.

Botryllamides A-D, new brominated tyrosine derivatives from styelid ascidians of the genus Botryllus

A. Carroll, C. Ireland, C. Fairchild, 1995 .

Nairaiamides A and B. two novel di-proline heptapeptides isolated from a fijian Lissoclinum bistratum ascidian.

M. Foster, C. Ireland, 1993 .

Detection of N-ras Mutations in Acute Myeloid Leukemia

C. Ireland, A. Todd, H. Iland, 1991 .

Marine‐Derived Fungi: A Chemically and Biologically Diverse Group of Microorganisms

C. Ireland, T. Bugni, 2004 .

Biomedical Potential of Marine Natural Products

D. Radisky, M. Foster, C. Ireland, 1993 .

Deoxyamphimedine, a Pyridoacridine Alkaloid, Damages DNA via the Production of Reactive Oxygen Species

C. Ireland, K. M. Marshall, D. Taşdemir, 2009, Marine drugs.

Antimalarial Activity of Crambescidin 800 and Synthetic Analogues against Liver and Blood Stage of Plasmodium sp.

P. Murphy, C. Ireland, G. Concepcion, 2006, The Journal of Antibiotics.

Lomaiviticins A and B, potent antitumor antibiotics from Micromonospora lomaivitiensis.

A. Richardson, C. Ireland, G. Carter, 2001, Journal of the American Chemical Society.

Total synthesis of dehaloperophoramidine using a highly diastereoselective Hosomi-Sakurai reaction.

A. Slawin, N. Westwood, C. Ireland, 2016, Chemical communications.

Isolation, structure determination, and biological activity of a novel alkaloid, perophoramidine, from the Philippine ascidian Perophora namei.

C. Ireland, G. Concepcion, Rohan A. Davis, 2002, The Journal of organic chemistry.

Lissoclinolide, the first non-nitrogenous metabolite from a Lissoclinum tunicate.

C. Ireland, B. S. Davidson, 1990, Journal of natural products.

Naamidine A is an antagonist of the epidermal growth factor receptor and an in vivo active antitumor agent.

S. Robinson, C. Ireland, C. Fairchild, 1998, Journal of medicinal chemistry.

Synthesis and biological evaluation of imidazoquinoxalinones, imidazole analogues of pyrroloiminoquinone marine natural products.

C. Ireland, D. LaBarbera, E. B. Skibo, 2007, Journal of medicinal chemistry.

Plakinidines: Cytotoxic alkaloid pigments from the fijian sponge plakortis sp.

J. Clardy, R. West, C. Ireland, 1990 .

Deoxyamphimedine, a new pyridoacridine alkaloid from two tropical Xestospongia sponges.

M. K. Harper, C. Ireland, K. M. Marshall, 2001, The Journal of organic chemistry.

Crispatone, a metabolite of the opisthobranch mollusc Tridachia crispata [1]

J. Clardy, C. Ireland, D. Faulkner, 1979 .

Tridachione, a propionate-derived metabolite of the opisthobranch mollusc Tridachiella diomedea

J. Clardy, C. Ireland, D. Faulkner, 1978 .

Cyclic peptide structures from the tunicate Lissoclinum patella by FAB mass spectrometry

C. Ireland, C. Costello, J. Biskupiak, 1983 .

Cytotoxic and antimicrobial alkaloids from the Fijian sponge Xestospongia caycedoi.

C. Ireland, T. Mckee, 1987, Journal of natural products.

6-Methoxy-7-methyl-8-oxoguanine, an unusual purine from the ascidian Symplegma rubra.

C. Ireland, C. J. Smith, B. S. Lindsay, 1999, Journal of natural products.

Cytotoxic Bromoindole Derivatives and Terpenes from the Philippine Marine Sponge Smenospongia sp.

M. K. Harper, C. Ireland, D. Taşdemir, 2002, Zeitschrift fur Naturforschung. C, Journal of biosciences.

Patellazole C: A Novel Cytotoxic Macrolide from Lissoclinum patella

C. Ireland, T. Zabriskie, C. Mayne, 1988 .

Araiosamines A-D: tris-bromoindole cyclic guanidine alkaloids from the marine sponge Clathria (Thalysias) araiosa.

Niel M. Henriksen, M. K. Harper, T. Cheatham, 2011, The Journal of organic chemistry.

Dictyosphaeric acids A and B: new decalactones from an undescribed Penicillium sp. obtained from the alga Dictyosphaeria versluyii.

R. Williamson, C. Ireland, T. Bugni, 2004, Journal of natural products.

Thiazoline peptides and a tris-phenethyl urea from Didemnum molle with anti-HIV activity.

M. K. Harper, C. Ireland, R. V. van Wagoner, 2012, Journal of natural products.

Microcionamides A and B, bioactive peptides from the philippine sponge Clathria (Thalysias) abietina.

M. K. Harper, C. Ireland, D. Taşdemir, 2004, The Journal of organic chemistry.

The Lobatamides, Novel Cytotoxic Macrolides from Southwestern Pacific Tunicates†

L. Pannell, M. Boyd, C. Ireland, 1998 .

Styelsamines A−D: New Tetracyclic Pyridoacridine Alkaloids from the Indonesian Ascidian Eusynstyela latericius

C. Ireland, J. Jompa, B. Copp, 1998 .

Rigidin E, a New Pyrrolopyrimidine Alkaloid from a Papua New Guinea Tunicate Eudistoma Species

A. Richardson, C. Ireland, Lane V. Christensen, 2003, Marine Drugs.

Cytotoxic metabolites from the mollusc peronia peronii

C. Ireland, J. Biskupiak, 1985 .

Ilikonapyrone esters, likely defense allomones of the mollusk Onchidium verruculatum

C. Ireland, G. Hite, P. Scheuer, 1984 .

Strongylophorine-8, a pro-electrophilic compound from the marine sponge Petrosia (Strongylophora) corticata, provides neuroprotection through Nrf2/ARE pathway.

M. K. Harper, C. Ireland, T. Satoh, 2011, Biochemical and biophysical research communications.

Antitumor activity and distribution of pyrroloiminoquinones in the sponge genus Zyzzya.

Chris M Ireland, Marie-Geneviève Dijoux, Peter C Schnabel, 2005, Bioorganic & medicinal chemistry.

Makaluvamines vary in ability to induce dose-dependent DNA cleavage via topoisomerase II interaction.

H. Haughey, J. Holden, C. Ireland, 1999, Anti-cancer drugs.

A rapid mechanism-based screen to detect potential anti-cancer agents.

C. Ireland, L. Barrows, D. S. Swaffar, 1994, Anti-cancer drugs.

Dysidazirine, a cytotoxic azacyclopropene from the marine sponge Dysidea fragilis

C. Ireland, T. Molinski, 1988 .

Metabolites of four nudibranchs of the genus Hypselodoris

C. Ireland, D. Faulkner, J. Hochlowski, 1982 .

Topoisomerase II-mediated DNA cleavage by adocia- and xestoquinones from the Philippine sponge Xestospongia sp.

G. Eldredge, J. Clardy, C. Ireland, 1995, Journal of medicinal chemistry.

Inhibition of topoisomerase II catalytic activity by pyridoacridine alkaloids from a Cystodytes sp. ascidian: a mechanism for the apparent intercalator-induced inhibition of topoisomerase II.

G. Eldredge, C. Ireland, L. Barrows, 1994, Journal of medicinal chemistry.

Isolation, structure determination, and biological activity of a novel alkaloid, perophoramidine, from the Philippine ascidian Perophora namei.

C. Ireland, G. Concepcion, Rohan A. Davis, 2002, The Journal of organic chemistry.

The metabolites of the marine molluscs Tridachiella diomedea and Tridachia crispata

J. Faulkner, C. Ireland, 1981 .

Photosynthetic Marine Mollusks: In vivo 14C Incorporation into Metabolites of the Sacoglossan Placobranchus ocellatus

C. Ireland, P. Scheuer, 1979, Science.

Novel polyketide metabolites from a species of marine fungi.

C. Ireland, J. Jompa, A. Tahir, 2000, Journal of natural products.

Salinamides A and B: anti-inflammatory depsipeptides from a marine streptomycete

J. Clardy, C. Ireland, P. Jensen, 1994 .

Investigations of the marine flora and fauna of the Fiji Islands.

M. K. Harper, C. Ireland, W. Aalbersberg, 2012, Natural product reports.

Isolation and structure determination of the didemnenones, novel cytotoxic metabolites from tunicates

J. Clardy, G. Duyne, C. Ireland, 1988 .

Making the most of Papua New Guinea’s biodiversity: Establishment of an integrated set of programs that link botanical survey with pharmacological assessment in “the land of the unexpected”

M. K. Harper, J. Jensen, C. Ireland, 2009, Pharmaceutical biology.

Pseudovibrio denitrificans strain Z143-1, a heptylprodigiosin-producing bacterium isolated from a Philippine tunicate.

C. Ireland, W. Barraquio, D. Taşdemir, 2007, FEMS microbiology letters.

Pseudovibrio denitri ¢ cans strainZ 1431 , a heptylprodigiosin-producing bacterium isolated fromaPhilippine tunicate

C. Ireland, W. Barraquio, D. Taşdemir, 2007 .

Varacin: a novel benzopentathiepin from Lissoclinum vareau that is cytotoxic toward a human colon tumor

C. Ireland, T. Molinski, L. Barrows, 1991 .

Varacin (I): A Novel Benzopentathiepin from Lissoclinum vareau That Is Cytotoxic Toward a Human Colon Tumor.

C. Ireland, T. Molinski, L. Barrows, 1991 .

The total synthesis of neoamphimedine.

C. Ireland, T. Bugni, D. LaBarbera, 2007, The Journal of organic chemistry.

Antineoplastic cyclic peptides from the marine tunicate Lissoclinum patella

Chris M. Ireland, C. Ireland, R. Newman, 1982 .

An iridoid glucoside from Euphrasia pectinata.

C. Ireland, İ. Çalış, D. Taşdemir, 2000, Journal of Natural Products.

Marine Natural Product Libraries for High-Throughput Screening and Rapid Drug Discovery

M. K. Harper, C. Ireland, T. Bugni, 2008, Journal of natural products.

Lucidin type anthraquinone glycosides from Putoria calabrica.

C. Ireland, İ. Çalış, O. Sticher, 2002, Chemical & pharmaceutical bulletin.

Flavonoid, iridoid, and lignan glycosides from Putoria calabrica.

C. Ireland, J. Heilmann, İ. Çalış, 2001, Journal of natural products.

Antimycobacterial activity of Exocarpos latifolius is due to exocarpic acid.

C. Ireland, L. Barrows, T. Bugni, 2009, Planta medica.

Neolignan Glucosides From Phlomis Chimerae Boiss

C. Ireland, İ. Çalış, D. Taşdemir, 2002, Zeitschrift fur Naturforschung. C, Journal of biosciences.

Yanuthones: novel metabolites from a marine isolate of Aspergillus niger.

C. Ireland, R. V. van Wagoner, T. Bugni, 2000, The Journal of organic chemistry.

Lissoclinotoxins E and F, Novel Cytotoxic Alkaloids from a Philippine Didemnid Ascidian.

C. Ireland, G. Concepcion, R. Rocha, 2003 .

Varamines A and B, new cytotoxic thioalkaloids from Lissoclinum vareau

C. Ireland, T. Molinski, 1989 .

3-bromohomofascaplysin A, a fascaplysin analogue from a Fijian Didemnum sp. ascidian.

C. Ireland, D. Ferreira, Xing-Cong Li, 2011, Bioorganic & medicinal chemistry.

A profile of the in vitro antitumor activity of lissoclinolide.

A. Richardson, C. Ireland, 2004, Toxicology and applied pharmacology.

Sebastianines A and B, novel biologically active pyridoacridine alkaloids from the Brazilian ascidian Cystodytes dellechiajei.

C. Ireland, A. Ferreira, A. Magalhães, 2002, The Journal of organic chemistry.

Diplamine, a cytotoxic polyaromatic alkaloid from the tunicate diplosoma sp.

C. Ireland, T. Mckee, G. A. Charyulu, 1989 .

A revised structure for the marine bromoindole derivative citorellamine

C. Ireland, R. Moriarty, C. Nelson, 1987 .

Identification and drug binding capabilities of tubulin in the nematode Ascaridia galli.

K. Gull, C. Ireland, C. I. Pogson, 1982, Molecular and biochemical parasitology.

DNA-protein crosslinks induced in a hamster tracheal epithelial cell line by benzo(a)pyrene.

A. Eastman, E. Bresnick, C. Ireland, 1982, Biochemical and biophysical research communications.

Revised structure of bistramide A (bistratene A): Application of a new program for the automated analysis of 2D INADEQUATE spectra

M. Foster, C. Ireland, D. Grant, 1992 .

Tubulin alterations in taxol-induced apoptosis parallel those observed with other drugs.

S. Pittman, C. Ireland, 1995, Biochemical pharmacology.

Chemical transformation of prostaglandin-A2: a novel series of C-10 halogenated, C-12 hydroxylated prostaglandin-A2 analogues.

C. Ireland, T. Bugni, J. Skalicky, 2006, Organic letters.

Some chemical constituents of the digestive gland of the sea hare Aplysia californica.

C. Ireland, D. Faulkner, M. Stallard, 1976, The Journal of organic chemistry.

Plakinidine D, a new pyrroloacridine alkaloid from two ascidians of the genus Didemnum.

C. Ireland, J. Jompa, C. Salomon, 1997, Journal of natural products.

p-Sulfooxyphenylpyruvic acid from the red macro alga Ceratodictyon spongiosum and its sponge symbiont Haliclona cymaeformis.

M. K. Harper, C. Ireland, T. Bugni, 2002, Phytochemistry.

The isolation and synthesis of polyandrocarpamines A and B. Two new 2-aminoimidazolone compounds from the Fijian ascidian, Polyandrocarpa sp.

C. Ireland, W. Aalbersberg, R. Rocha, 2002 .

The Chemistry of Lissoclinum Patella

S. Gaskell, C. Ireland, D. F. Sesin, 2010 .

Bolinaquinone: A novel cytotoxic sesquiterpene hydroxyquinone from a Philippine Dysidea sponge

C. Ireland, B. Copp, G. Concepcion, 1998 .

Naamidine A intensifies the phosphotransferase activity of extracellular signal-regulated kinases causing A-431 cells to arrest in G1.

David A Jones, C. Ireland, W. Aalbersberg, 2003, Molecular Cancer Therapeutics.

Fibrosterol sulfates from the Philippine sponge Lissodendoryx (Acanthodoryx) fibrosa: sterol dimers that inhibit PKCzeta.

M. K. Harper, C. Ireland, T. Bugni, 2009, The Journal of organic chemistry.

Inhibition of tubulin polymerization by vitilevuamide, a bicyclic marine peptide, at a site distinct from colchicine, the vinca alkaloids, and dolastatin 10.

P. Lassota, C. Ireland, L. Barrows, 2002, Biochemical pharmacology.

Mirabamides E-H, HIV-inhibitory depsipeptides from the sponge Stelletta clavosa.

M. K. Harper, C. Bewley, C. Ireland, 2011, Journal of natural products.

The isolation and structure of modified bioactive nucleosides from Jaspis johnstoni.

C. Ireland, T. Zabriskie, 1989, Journal of natural products.

Model Studies on the in Vitro Activation of c-Ha-ras Protooncogene by Dietary Components

C. Cooper, D. Phillips, C. Ireland, 1988 .

Penicillium dravuni, a new marine-derived species from an alga in Fiji.

C. Ireland, T. Bugni, J. Janso, 2005, Mycologia.

Fractionated Marine Invertebrate Extract Libraries for Drug Discovery

Mary Kay Harper, Chris M. Ireland, M. K. Harper, 2008, Molecules.

The anti-neoplastic and novel topoisomerase II-mediated cytotoxicity of neoamphimedine, a marine pyridoacridine.

J. Holden, C. Ireland, K. M. Marshall, 2003, Biochemical pharmacology.

Cytotoxic isoquinoline quinones from sponges of the genus Petrosia

M. K. Harper, C. Ireland, T. Bugni, 2004, Natural product research.

Anticancer Agents from Unique Natural Products Sources

M. K. Harper, T. Fojo, R. Andersen, 2003 .

The Tumor Suppressor Adenomatous Polyposis Coli and Caudal Related Homeodomain Protein Regulate Expression of Retinol Dehydrogenase L*

E. Manos, David A Jones, C. Ireland, 2004, Journal of Biological Chemistry.

Upright emergence in Petalura gigantea (Odonata: Petaluridae)

C. Ireland, Ian R. C. Baird, 2006 .

PREPACIFENOL EPOXIDE, A HALOGENATED SESQUITERPENE DIEPOXIDE

C. Ireland, D. Faulkner, M. Stallard, 1975 .

Prefacifenol epoxide, a halogenated sesquiterpene diepoxide

C. Ireland, D. Faulkner, M. Stallard, 1974 .

Effect of juvenile hormone on cirriped metamorphosis.

C. Ireland, D. Faulkner, M. Ramenofsky, 1974, Biochemical and biophysical research communications.

The defensive secretion of the opisthobranch mollusc Onchidella binneyi

C. Ireland, D. Faulkner, 1978 .

Muamvatin, a novel tricyclic spiro ketal from the Fijian mollusc Siphonaria normalis

C. Ireland, J. Biskupiak, D. Roll, 1986 .

Pectinatone, a new antibiotic from the mollusc siphonaria pectinata

C. Ireland, J. Biskupiak, 1983 .

Diterpenes from Dolabella californica.

C. Ireland, D. Faulkner, 1977, The Journal of organic chemistry.

New Terpenoids from a Cacospongia sp. from the Philippines

M. K. Harper, C. Ireland, D. Taşdemir, 2000 .

Letter: A novel diterpene from Dollabella californica.

J. Clardy, C. Ireland, D. Faulkner, 1976, Journal of the American Chemical Society.

Bioactive compounds from the sea

D. Radisky, M. Foster, C. Ireland, 2000 .

Platelet Aggregation Inhibitors from Philippine Marine Invertebrate Samples Screened in a New Microplate Assay

C. Ireland, D. Taşdemir, G. Concepcion, 2003, Marine Biotechnology.

The marine alkaloid naamidine A promotes caspase-dependent apoptosis in tumor cells

M. K. Harper, N. Moghal, C. Ireland, 2009, Anti-cancer drugs.

Endo-exonuclease of human leukaemic cells: evidence for a role in apoptosis.

S. Pittman, C. Ireland, A. Papaioannou, 1996, Journal of cell science.

Accessing chemical diversity from the uncultivated symbionts of small marine animals

Malcolm M. Zachariah, M. K. Harper, Thomas E. Smith, 2017, Nature chemical biology.

Mamanuthaquinone: an antimicrobial and cytotoxic metabolite of Fasciospongia sp.

C. Ireland, L. Barrows, J. C. Swersey, 1991 .

Aldisine alkaloids from the Philippine sponge Stylissa massa are potent inhibitors of mitogen-activated protein kinase kinase-1 (MEK-1).

M. K. Harper, C. Ireland, D. Wojciechowicz, 2002, Journal of medicinal chemistry.

Makaluvamines, marine natural products, are active anti-cancer agents and DNA topo II inhibitors.

D. Radisky, R. Warters, C. Ireland, 1993, Anti-cancer drug design.

A new cytotoxic and tubulin-interactive milnamide derivative from a marine sponge Cymbastela sp.

M. K. Harper, A. Richardson, C. Ireland, 2003, Organic letters.

Up-regulation of CYP26A1 in adenomatous polyposis coli-deficient vertebrates via a WNT-dependent mechanism: implications for intestinal cell differentiation and colon tumor development.

D. Shelton, David A Jones, C. Ireland, 2006, Cancer research.

Trypargine alkaloids from a previously undescribed Eudistoma sp. ascidian.

C. Ireland, R. V. van Wagoner, J. Jompa, 1999, Journal of natural products.

Resistance to apoptotic cell death in a drug resistant T cell leukaemia cell line.

S. Pittman, M. Geyp, C. Ireland, 1996, Leukemia.

An investigation of a possible role for mitochondrial nuclease in apoptosis

C. Ireland, X. Meng, J. Feller, 1998, Apoptosis.

Agelasine F from a Philippine Agelas sp. sponge exhibits in vitro antituberculosis activity.

A. Richardson, C. Ireland, S. Franzblau, 2000, Planta medica.

Carteriosulfonic acids A-C, GSK-3beta inhibitors from a Carteriospongia sp.

M. K. Harper, C. Ireland, D. Virshup, 2009, Journal of natural products.

Dual roles for adenomatous polyposis coli in regulating retinoic acid biosynthesis and Wnt during ocular development

D. Shelton, L. Nadauld, E. Manos, 2006, Proceedings of the National Academy of Sciences.

Brocaenols A—C: Novel Polyketides from a Marine-Derived Penicillium brocae.

C. Ireland, T. Bugni, J. Janso, 2003 .

Thin-layer chromatographic and high-performance liquid chromatographic separation of metabolites of the weak carcinogen, 7-methylbenz[c]acridine.

C. Ireland, G. Holder, A. J. Ryan, 1982, Journal of chromatography.

Rat liver microsomal metabolites of 7-methylbenz[c]acridine.

C. Ireland, G. Holder, A. J. Ryan, 1982, Chemico-biological interactions.

Differences in the topoisomerase I cleavage complexes formed by camptothecin and wakayin, a DNA‐intercalating marine natural product

J. Holden, C. Ireland, L. Barrows, 1996, Anti-cancer drugs.

Bistramides A, B, C, D, and K: a new class of bioactive cyclic polyethers from Lissoclinum bistratum.

M. Foster, C. Ireland, P. Cotelle, 1994, Journal of natural products.

New Destruxins from the Marine-derived Fungus Beauveria felina

C. Ireland, R. Berlinck, T. Bugni, 2006, The Journal of Antibiotics.

Kalihinols from two Acanthella cavernosa sponges: inhibitors of bacterial folate biosynthesis

M. K. Harper, C. Ireland, T. Bugni, 2004 .

Kalihinols from Two Acanthella cavernosa Sponges: Inhibitors of Bacterial Folate Biosynthesis.

M. K. Harper, C. Ireland, T. Bugni, 2004 .

The patellazoles inhibit protein synthesis at nanomolar concentrations in human colon tumor cells

A. Richardson, C. Ireland, W. Aalbersberg, 2005, Anti-cancer drugs.

Citorellamine, a new bromoindole derivative from polycitorella mariae

C. Ireland, D. Roll, 1985 .

Revised absolute configuration of dysidenin and isodysidenin

C. Ireland, J. Biskupiak, 1984 .

Neoamphimedine: A New Pyridoacridine Topoisomerase II Inhibitor which Catenates DNA.

M. K. Harper, C. Ireland, L. Barrows, 1999 .

Namenamicin, a New Enediyne Antitumor Antibiotic from the Marine Ascidian Polysyncraton lithostrotum.

C. Ireland, C. Discafani, G. Krishnamurthy, 1997 .

The Chemistry of Some Opisthobranch Molluscs

C. Ireland, D. Faulkner, 1977 .

Characterization of a strain-specific inhibitor of cell division from Amoeba cytoplasm.

C. Ireland, S. Hawkins, 1980, Journal of cell science.

Change in compatibility after microinjection of cytoplasm in amoebae

C. Ireland, S. Hawkins, 1980, Experientia.

Single-molecule inhibition of human kinesin by adociasulfate-13 and -14 from the sponge Cladocroce aculeata

Mary Kay Harper, Michael Vershinin, Weili Hong, 2013, Proceedings of the National Academy of Sciences.

Psammaplysin C: a new cytotoxic dibromotyrosine-derived metabolite from the marine sponge Druinella (= Psammaplysilla) purpurea.

C. Ireland, L. Barrows, B. Copp, 1992, Journal of natural products.

Marine natural products as inhibitors of cystathionine beta-synthase activity.

M. K. Harper, C. Ireland, R. V. van Wagoner, 2015, Bioorganic & medicinal chemistry letters.

Cyclic peptide structures from the tunicate Lissoclinum patella by FAB mass spectrometry

C. Ireland, C. Costello, J. Biskupiak, 1983 .

Jaspamide (I), a Modified Peptide from a Jaspis Sponge, with Insecticidal and Antifungal Activity.

J. Clardy, C. Ireland, T. Molinski, 1986 .

Tubercidin analogs from the ascidian Didemnum voeltzkowi.

C. Ireland, G. Concepcion, S. Pomerantz, 1996, Journal of natural products.

Patellins 1‐6 and Trunkamide A: Novel Cyclic Hexa‐, Hepta‐ and Octa‐ Peptides from Colonial Ascidians, Lissoclinum sp.

A. Carroll, C. Ireland, J. Coll, 1996 .

Spheciosterol Sulfates, PKCζ Inhibitors from a Philippine Sponge Spheciospongia sp.

M. K. Harper, C. Ireland, T. Bugni, 2008, Journal of natural products.

Analysis of N‐ras gene mutations in acute myeloid leukemia by allele specific restriction analysis

C. Ireland, H. Kronenberg, A. Todd, 1991, American journal of hematology.

Single-molecule inhibition of human kinesin by adociasulfate-13 and -14 from the sponge Cladocroce aculeata

Malcolm M. Zachariah, M. K. Harper, Thomas E. Smith, 2013, Proceedings of the National Academy of Sciences.

Veiutamine. A new alkaloid from the Fijian sponge Zyzzya fuliginosa

P. Lassota, C. Ireland, L. Barrows, 1997 .

The marine alkaloid naamidine A promotes caspase-dependent apoptosis in tumor cells

M. K. Harper, N. Moghal, C. Ireland, 2009, Anti-cancer drugs.

Strongylophorines: natural product inhibitors of hypoxia-inducible factor-1 transcriptional pathway.

M. K. Harper, C. Ireland, T. Bugni, 2008, Journal of medicinal chemistry.

Polymerization of tubulin in apoptotic cells is not cell cycle dependent.

D. Strickland, S. Pittman, C. Ireland, 1994, Experimental cell research.