J. Heighway

R. Booton, T. Ward, Julie Morris, 2007, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Constitutional frequencies of c-Ha-ras alleles in patients with different types of lung cancer.

M. Santibanez-Koref, J. Heighway, G. White, 1990, British Journal of Cancer.

Abnormal expression of CCND1 and RB1 in resection margin epithelia of lung cancer patients.

P. Hasleton, J. Heighway, D. Betticher, 1997, British Journal of Cancer.

A transcribed polymorphism and sub-localisation of MDM2

J. Heighway, E. Mitchell, G. White, 1994, Human Genetics.

Linkage studies in a Li-Fraumeni family with increased expression of p53 protein but no germline mutation in p53.

D. Lane, M. Santibanez-Koref, M. Teare, 1994, British Journal of Cancer.

p21 is associated with cyclin D1, p16INK4a and pRb expression in resectable non-small cell lung cancer.

M. Borner, J. Heighway, D. Betticher, 2000, International journal of oncology.

Linkage studies inaLi-Fraumeni family withincreased expression ofp53 protein butno germline mutation inp53

J. Heighway, J. Birch, A. Kelsey, 1994 .

Lung: Small cell cancer

J. Heighway, D. Betticher, 2011 .

Abstracts of the 7th International Workshop on AT, November, 1997, Clermont-Ferrand, France

T. Stankovic, A. Taylor, J. Varley, 2002, Disease markers.

Maspin – the most commonly-expressed gene of the 18q21.3 serpin cluster in lung cancer – is strongly expressed in preneoplastic bronchial lesions

J. Heighway, D. Betticher, M. Gugger, 2003, Oncogene.

Detailed mapping and loss of heterozygosity analysis suggests a suppressor locus involved in sporadic breast cancer within a distal region of chromosome band 17p13.3.

J. Varley, T. Venesio, J. Heighway, 1995, Human molecular genetics.

An expectation-maximization algorithm for the analysis of allelic expression imbalance.

M. Teare, J. Heighway, M. S. Santibáñez Koref, 2006, American journal of human genetics.

SspI polymorphism in sequence encoding 3' untranslated region of the APC gene.

A. Wyllie, J. Heighway, P. Hoban, 1991, Nucleic acids research.

PCR primers to convert c-Ki-ras to a four allele RsaI system (KRAS2).

J. Heighway, 1991, Nucleic acids research.

Measuring the METH-2 promoter hypermethylation and transcript downregulation in non-small cell lung carcinomas with the Agilent 2100 bioanalyzer

T. Liloglou, J. Heighway, D. Panutsopulos, 2005 .

METH-2 silencing and promoter hypermethylation in NSCLC

T. Liloglou, J. Heighway, S. Watson, 2004, British Journal of Cancer.

Nanospan, an alternatively spliced isoform of sarcospan, localizes to the sarcoplasmic reticulum in skeletal muscle and is absent in limb girdle muscular dystrophy 2F

J. Heighway, R. Coral-Vázquez, M. DiFranco, 2017, Skeletal Muscle.

Isolation and characterization of a human homologue of the latrophilin gene from a region of 1p31.1 implicated in breast cancer

J. Varley, J. Heighway, G. White, 1998, Oncogene.

Decreased endothelin receptor B expression in large primary uveal melanomas is associated with early clinical metastasis and short survival

J. Heighway, B. Damato, J. Field, 2002, British Journal of Cancer.

Transcription of a stem/loop region of a tumour-amplified sequence induces bacterial aggregation.

J. Heighway, K. Leverton, 1991, Journal of general microbiology.

Coamplification in tumors of KRAS2, type 2 inositol 1,4,5 triphosphate receptor gene, and a novel human gene, KRAG.

J. Heighway, P. Hoban, D. Betticher, 1996, Genomics.

Prognostic significance of CCND1 (cyclin D1) overexpression in primary resected non-small-cell lung cancer.

W. Ryder, P. Hasleton, J. Heighway, 1996, British Journal of Cancer.

The use of Allelic Expression Differences to Ascertain Functional Polymorphisms Acting in cis: Analysis of MMP1 Transcripts in Normal Lung Tissue

J. Heighway, N. Bowers, D. Betticher, 2005, Annals of human genetics.

Cyclin D1 in non-small cell lung cancer: a key driver of malignant transformation.

Oliver Gautschi, J. Heighway, D. Betticher, 2007, Lung Cancer.

Identification of the critical region of 12p over-representation in testicular germ cell tumors of adolescents and adults

P. Marynen, L. Looijenga, A. Verkerk, 1998, Oncogene.

Quantitative trait locus analysis reveals two intragenic sites that influence O6-alkylguanine-DNA alkyltransferase activity in peripheral blood mononuclear cells.

S. Lewis, P. Barber, M. Santibanez-Koref, 2005, Carcinogenesis.

Quantitative trait locus analysis reveals two intragenic sites that influence O 6-alkylguanine-DNA alkyltransferase activity in peripheral blood mononuclear cells

S. Lewis, P. Barber, G. Margison, 2005 .

The alleles of the DNA repair gene O6-alkylguanine-DNA alkyltransferase are expressed at different levels in normal human lung tissue.

M. Santibanez-Koref, G. Margison, J. Heighway, 2003, Carcinogenesis.

Sarcospan, the 25-kDa Transmembrane Component of the Dystrophin-Glycoprotein Complex*

K. Campbell, J. Heighway, D. Venzke, 1997, The Journal of Biological Chemistry.

Aurora Kinases as Anticancer Drug Targets

Oliver Gautschi, D. Gandara, J. Heighway, 2008, Clinical Cancer Research.

Overexpression of aurora B kinase (AURKB) in primary non-small cell lung carcinoma is frequent, generally driven from one allele, and correlates with the level of genetic instability

R. Booton, M. Santibanez-Koref, J. Heighway, 2005, British Journal of Cancer.

Comparing Methods for Mapping cis Acting Polymorphisms Using Allelic Expression Ratios

M. Teare, J. Heighway, S. Pinyakorn, 2011, PloS one.

Alterations of cell cycle regulators are less frequent in advanced non-small cell lung cancer than in resectable tumours.

M. Borner, J. Heighway, D. Betticher, 2001, Lung cancer.

Alternate splicing produces a novel cyclin D1 transcript.

N Thatcher, W. Ryder, J. Heighway, 1995, Oncogene.

Cyclin D1 overexpression in bronchial epithelia of patients with lung cancer is associated with smoking and predicts survival.

M. Borner, J. Heighway, A. Kappeler, 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Cyclin D1 (CCND1) A870G gene polymorphism modulates smoking-induced lung cancer risk and response to platinum-based chemotherapy in non-small cell lung cancer (NSCLC) patients.

R. Stahel, A. Ziegler, J. Heighway, 2006, Lung cancer.

Induced expression of human CCND1 alternative transcripts in mouse Cyl‐1 knockout fibroblasts highlights functional differences

J. Heighway, S. Holley, P. Hoban, 2005, International journal of cancer.

Cyclin D 1 O verexpression i n B ronchial E pithelia o f Patients W ith L ung C ancer I s A ssociated W ith S moking a nd Predicts S urvival

J. Heighway, A. Kappeler, M. Gugger, 2003 .

Lung: Non-small cell carcinoma

J. Heighway, D. Betticher, 2011 .

c-Ki-ras amplification in human lung cancer.

P. Hasleton, J. Heighway, 1986, British Journal of Cancer.

Genome-wide loss of maternal alleles in a nephrogenic rest and Wilms' tumour from a BWS patient

J. Heighway, J. Birch, A. Kelsey, 1995, Human Genetics.

N‐myc gene is amplified in alveolar rhabdomyosarcomas (RMS) but not in embryonal RMS

H. Marsden, J. Heighway, H. Gattamaneni, 1990, International journal of cancer.

Xeroderma pigmentosum group D haplotype predicts for response, survival, and toxicity after platinum‐based chemotherapy in advanced nonsmall cell lung cancer

R. Booton, T. Ward, Julie Morris, 2006, Cancer.

Origin and prognostic value of circulating KRAS mutations in lung cancer patients.

D. Gandara, R. Stahel, H. Kung, 2007, Cancer letters.

Isolation of a human genomic fragment, co-amplified with c-Ki-ras, that affects plasmid supercoiling in E. coli.

J. Heighway, A. G. V. Geurts van Kessel, 1987, Nucleic Acids Research.

Expression profiling of primary non-small cell lung cancer for target identification

J. Heighway, P. Rickert, D. Betticher, 2002, Oncogene.

A strategy for the rapid isolation of new PCR based DNA polymorphisms.

M. Santibanez-Koref, J. Heighway, P. Hoban, 1992, Journal of medical genetics.

HaeIII polymorphism within 3' untranslated region of PRAD1.

J. Heighway, 1991, Nucleic acids research.

DdeI polymorphism within sequence encoding 3' untranslated region of c-Ki-ras2 (KRAS2).

J. Heighway, 1991, Nucleic acids research.

RsaI polymorphism in c-Ki-ras.

J. Heighway, 1991, Nucleic acids research.

BsmI polymorphism in N-ras intron I (RASN).

J. Heighway, 1991, Nucleic Acids Research.

A strategyfortherapid isolation ofnew PCR basedDNA polymorphisms

M. Santibanez-Koref, J. Heighway, P. Hoban, 2017 .

Over-expression of Microspan, a novel component of the sarcoplasmic reticulum, causes severe muscle pathology with triad abnormalities

J. Heighway, Angela K. Peter, R. Crosbie, 2006, Journal of Muscle Research & Cell Motility.

S100A2 is strongly expressed in airway basal cells, preneoplastic bronchial lesions and primary non-small cell lung carcinomas

J. Heighway, P. Hoban, D. Betticher, 2004, British Journal of Cancer.

Absence of mutations in the ATM gene in breast cancer patients with severe responses to radiotherapy.

T. Stankovic, A. Taylor, J. Varley, 1997, British Journal of Cancer.

Constitutional frequency of rare alleles of c-Ha-ras in breast cancer patients.

J. Heighway, G. Williams, G. White, 1988, British Journal of Cancer.

FOLFOX4 with cetuximab vs. UFOX with cetuximab as first-line therapy in metastatic colorectal cancer: The randomized phase II FUTURE study.

M. Schlichting, J. Douillard, J. Heighway, 2014, Clinical colorectal cancer.

Physical localisation of the breakpoints of a constitutional translocation t(5;6)(q21;q21) in a child with bilateral Wilms' tumour.

D. Evans, J. Heighway, E. Mitchell, 1997, Journal of medical genetics.

Lung tumors: an overview

J. Heighway, D. Betticher, 2011 .

MaeIII polymorphism in sequence encoding 3' untranslated region of the MCC gene.

A. Wyllie, J. Heighway, P. Hoban, 1992, Nucleic acids research.

Meta-analysis of individual patient data from randomized trials of chemotherapy plus cetuximab as first-line treatment for advanced non-small cell lung cancer.

K. O'Byrne, T. Lynch, F. Shepherd, 2014, Lung cancer.

Nanospan, an alternatively spliced isoform of sarcospan, localizes to the sarcoplasmic reticulum in skeletal muscle and is absent in limb girdle muscular dystrophy 2F

J. Heighway, R. Coral-Vázquez, M. DiFranco, 2017, Skeletal Muscle.

Glutathione-S-Transferase P1 Isoenzyme Polymorphisms, Platinum-Based Chemotherapy, and Non-small Cell Lung Cancer

T. Ward, Julie Morris, J. Heighway, 2006, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Mapping of gene loci in the Q13–Q15 region of chromosome 12

J. Varley, M. Santibanez-Koref, J. Heighway, 1995, Chromosome Research.

Anonymous genomic fragment co-amplified with c-Ki-ras 2 detects frequent polymorphism (pK42).

J. Heighway, A. G. V. Geurts van Kessel, 1986, Nucleic acids research.

FOLFOX4 with cetuximab vs. UFOX with cetuximab as first-line therapy in metastatic colorectal cancer: The randomized phase II FUTURE study.

M. Schlichting, J. Douillard, J. Heighway, 2014, Clinical colorectal cancer.