J. Wysolmerski

E. Zelazny, A. Perkins, J. Wysolmerski, 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Physiological Actions of Parathyroid Hormone (PTH) and PTH-Related Protein: Epidermal, Mammary, Reproductive, and Pancreatic Tissues

J. Wysolmerski, 2002 .

Temporally regulated overexpression of parathyroid hormone-related protein in the mammary gland reveals distinct fetal and pubertal phenotypes.

J. Wysolmerski, M. Dunbar, C. W. Brown, 2001, The Journal of endocrinology.

CHAPTER 17 – Physiologic Actions of PTH and PTHrP: V. Epidermal, Mammary, Reproductive, and Pancreatic Tissues

A. F. Stewart, J. Wysolmerski, A. Stewart, 2001 .

Identification of a novel 17,000-dalton parathyroid hormone-like adenylate cyclase-stimulating protein from a tumor associated with humoral hypercalcemia of malignancy.

A. F. Stewart, J. Wysolmerski, A. Broadus, 1987, The Journal of biological chemistry.

Treatment of Osteoporosis and Osteopenia in Long‐term Renal Transplant Patients with Alendronate

A. Kliger, A. Friedman, J. Wysolmerski, 2002, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Overexpression of parathyroid hormone-related protein in the skin of transgenic mice interferes with hair follicle development.

E. Fuchs, J. Wysolmerski, A. Broadus, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Nipple connective tissue and its development: insights from the K14-PTHrP mouse

J. Foley, J. Wysolmerski, R. Sellers, 2002, Mechanisms of Development.

Mammary-specific deletion of parathyroid hormone-related protein preserves bone mass during lactation.

C. Watson, A. F. Stewart, J. Wysolmerski, 2003, The Journal of clinical investigation.

Skeletal Recovery After Weaning Does Not Require PTHrP

J. Wysolmerski, C. Kovacs, N. Sims, 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Site‐specific changes in bone microarchitecture, mineralization, and stiffness during lactation and after weaning in mice

E. Shane, X. S. Liu, J. Wysolmerski, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Parathyroid Hormone, Parathyroid Hormone–Related Protein, and Calcitonin

J. Wysolmerski, E. Holt, 2011 .

Continuous PTH and PTHrP Infusion Causes Suppression of Bone Formation and Discordant Effects on 1,25(OH)2Vitamin D

S. Sereika, A. F. Stewart, J. Wysolmerski, 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

POSTTRANSPLANT BONE DISEASE: EVIDENCE FOR A HIGH BONE RESORPTION STATE

A. Kliger, A. Friedman, J. Wysolmerski, 2000, Transplantation.

Molecular mechanisms guiding embryonic mammary gland development.

J. Wysolmerski, P. Cowin, 2010, Cold Spring Harbor perspectives in biology.

Regulation of parathyroid hormone-related protein gene expression in murine keratinocytes by E1A isoforms: a role for basal promoter and Ets-1 site

C. Missero, J. Foley, J. Wysolmerski, 1999, Molecular and Cellular Endocrinology.

Identification and characterization of a GC-rich promoter of the human parathyroid hormone-related peptide gene.

J. Wysolmerski, A. Broadus, W. Philbrick, 1993, Molecular endocrinology.

The Evolutionary Origins of Maternal Calcium and Bone Metabolism During Lactation

J. Wysolmerski, 2002, Journal of Mammary Gland Biology and Neoplasia.

Overexpression of parathyroid hormone-related protein or parathyroid hormone in transgenic mice impairs branching morphogenesis during mammary gland development.

J. Wysolmerski, A. Broadus, W. Philbrick, 1995, Development.

Defining the roles of parathyroid hormone-related protein in normal physiology.

J. Orloff, A. F. Stewart, J. Wysolmerski, 1996, Physiological reviews.

Hypercalcemia of malignancy: the central role of parathyroid hormone-related protein.

J. Wysolmerski, A. Broadus, 1994, Annual review of medicine.

Low estrogen and high parathyroid hormone-related peptide levels contribute to accelerated bone resorption and bone loss in lactating mice.

J. Wysolmerski, J. Vanhouten, 2003, Endocrinology.

Award Number: DAMD17-96-1-6198 TITLE: The Role of PTHrP in Mammary Gland Development and Tumorigenesis

L. Hennighausen, G. Robinson, J. Wysolmerski, 2018 .

Mammary ductal and alveolar development: Lesson learned from genetically manipulated mice

J. Wysolmerski, M. Dunbar, John J. Wysolmerski, 2001, Microscopy research and technique.

HER2 signaling regulates HER2 localization and membrane retention

J. Wysolmerski, L. Kim, Jaekwang Jeong, 2017, PloS one.

PTHrP regulates epidermal differentiation in adult mice.

J. Foley, J. Wysolmerski, A. Broadus, 1998, The Journal of investigative dermatology.

Switching of G-protein Usage by the Calcium-sensing Receptor Reverses Its Effect on Parathyroid Hormone-related Protein Secretion in Normal Versus Malignant Breast Cells*

R. Mamillapalli, J. Wysolmerski, W. Zawalich, 2008, Journal of Biological Chemistry.

The Calcium-Sensing Receptor Regulates Plasma Membrane Calcium Adenosine Triphosphatase Isoform 2 Activity in Mammary Epithelial Cells: A Mechanism for Calcium-Regulated Calcium Transport into Milk

M. Neville, J. Wysolmerski, J. Vanhouten, 2007, Endocrinology.

Parathyroid hormone-related protein: an update.

J. Wysolmerski, 2012, The Journal of clinical endocrinology and metabolism.

Cancer-Associated Hypercalcemia.

J. Wysolmerski, T. Guise, 2022, The New England journal of medicine.

PTHrP and breast cancer: more than hypercalcemia and bone metastases

J. Wysolmerski, Kata Boras-Granic, 2012, Breast Cancer Research.

Mammary-specific ablation of the calcium-sensing receptor during lactation alters maternal calcium metabolism, milk calcium transport, and neonatal calcium accrual.

R. Mamillapalli, E. Brown, J. Wysolmerski, 2013, Endocrinology.

OPG Treatment Prevents Bone Loss During Lactation But Does Not Affect Milk Production or Maternal Calcium Metabolism.

P. Kostenuik, J. Wysolmerski, C. Dumitru, 2015, Endocrinology.

Weaning triggers a decrease in receptor activator of nuclear factor-kappaB ligand expression, widespread osteoclast apoptosis, and rapid recovery of bone mass after lactation in mice.

J. Wysolmerski, M. Horowitz, D. Adams, 2007, Endocrinology.

The calcium-sensing receptor regulates PTHrP production and calcium transport in the lactating mammary gland.

J. Wysolmerski, M. Pollak, P. Dann, 2006, Bone.

Conversations between breast and bone: Physiological bone loss during lactation as evolutionary template for osteolysis in breast cancer and pathological bone loss after menopause

J. Wysolmerski, 2007 .

Chapter 26. Parathyroid Hormone–Related Protein

J. Wysolmerski, 2009 .

Interactions between breast, bone, and brain regulate mineral and skeletal metabolism during lactation

J. Wysolmerski, 2010, Annals of the New York Academy of Sciences.

Identification and characterization of a GC-rich promoter of the human parathyroid hormone-related peptide gene.

J. Wysolmerski, A. Broadus, W. Philbrick, 1993, Molecular endocrinology.

Preservation of β-Galactosidase Transgene in Decalcified Murine Bone Specimens Embedded in Paraffin

J. Wysolmerski, M. Kacena, N. Troiano, 2008 .

A syndrome of hypocalciuric hypercalcemia caused by autoantibodies directed at the calcium-sensing receptor.

J. Garber, E. Brown, J. Wysolmerski, 2003, The Journal of clinical endocrinology and metabolism.

Intracellular Calcium links Milk Stasis to Lysosome Dependent Cell Death during Mammary Gland Involution Cell death during involution

Dann, J. Wysolmerski, Diana Athonvarangkul, 2022 .

Demonstration of osteocytic perilacunar/canalicular remodeling in mice during lactation

Hai Qing, L. Bonewald, S. Kato, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Deletion of the Nuclear Localization Sequences and C-Terminus of PTHrP Impairs Embryonic Mammary Development but also Inhibits PTHrP Production

J. Wysolmerski, A. Karaplis, P. Dann, 2014, PloS one.

Absence of functional type 1 parathyroid hormone (PTH)/PTH-related protein receptors in humans is associated with abnormal breast development and tooth impaction.

J. Wysolmerski, W. Philbrick, J. Roume, 2001, The Journal of clinical endocrinology and metabolism.

Osteocytic osteolysis: time for a second look?

J. Wysolmerski, 2012, BoneKEy reports.

The physiology of parathyroid hormone-related protein: an emerging role as a developmental factor.

A. F. Stewart, J. Wysolmerski, 1998, Annual review of physiology.

Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis

S. Millar, C. Brisken, J. Wysolmerski, 2004, Development.

Attacking Breast Cancer at the Preinvasion Stage by Targeting Autophagy

L. Liotta, V. Espina, J. Wysolmerski, 2013, Women's health.

Parathyroid hormone-related protein signaling is necessary for sexual dimorphism during embryonic mammary development.

L. Hennighausen, G. Robinson, J. Wysolmerski, 1999, Development.

Stromal cells are critical targets in the regulation of mammary ductal morphogenesis by parathyroid hormone-related protein.

J. Orloff, B. Lanske, J. Wysolmerski, 1998, Developmental biology.

The calcium-sensing receptor couples to Galpha(s) and regulates PTHrP and ACTH secretion in pituitary cells.

R. Mamillapalli, J. Wysolmerski, 2010, The Journal of endocrinology.

Key stages of mammary gland development: Molecular mechanisms involved in the formation of the embryonic mammary gland

J. Wysolmerski, Julie R Hens, John J Wysolmerski, 2005, Breast Cancer Research.

Calcium-Sensing Receptor Promotes Breast Cancer by Stimulating Intracrine Actions of Parathyroid Hormone-Related Protein.

Herbert Yu, J. Wysolmerski, N. Fiaschi-Taesch, 2016, Cancer research.

The butyrophilin 1a1 knockout mouse revisited: Ablation of Btn1a1 leads to concurrent cell death and renewal in the mammary epithelium during lactation

L. Jenkins, J. Wysolmerski, R. Weigert, 2021, FASEB bioAdvances.

Activation of PTHrP gene expression in squamous carcinoma cell lines by mutant isoforms of the tumor suppressor p53.

J. Foley, J. Wysolmerski, W. Philbrick, 2001, Oncology research.

Embryonic cells contribute directly to the quiescent stem cell population in the adult mouse mammary gland

J. Wysolmerski, P. Dann, Kata Boras-Granic, 2014, Breast Cancer Research.

Parathyroid Hormone-Related Protein Is Not Required for Normal Ductal or Alveolar Development in the Post-Natal Mammary Gland

J. Wysolmerski, M. Hiremath, Kata Boras-Granic, 2011, PloS one.

Crosstalk within a brain-breast-bone axis regulates mineral and skeletal metabolism during lactation

J. Wysolmerski, Diana Athonvarangkul, 2023, Frontiers in Physiology.

Inhibition of ezrin causes PKCα-mediated internalization of erbb2/HER2 tyrosine kinase in breast cancer cells

P. A. Friedman, J. Wysolmerski, Jungmin Choi, 2018, The Journal of Biological Chemistry.

Chapter 57 – Parathyroid Hormone-Related Protein

J. Wysolmerski, 2016 .

Chapter 13 – Physiological Actions of Parathyroid Hormone (PTH) and PTH-related Protein: Epidermal, Mammary, Reproductive, and Pancreatic Tissues

J. Wysolmerski, 2015 .

PARATHYROID HORMONE-RELATED PROTEIN I 127

J. Wysolmerski, 2009 .

Parathyroid Hormone-Related Protein: A Developmental Regulatory Molecule Necessary for Mammary Gland Development

J. Wysolmerski, M. Dunbar, 2004, Journal of Mammary Gland Biology and Neoplasia.

Parathyroid hormone-related protein: from hypercalcemia of malignancy to developmental regulatory molecule.

J. Wysolmerski, A. Broadus, M. Dunbar, 1996, The American journal of the medical sciences.

PTHrP Induces STAT5 Activation, Secretory Differentiation and Mammary Tumor Progression

L. Chodosh, J. Wysolmerski, Martín E. García Solá, 2021 .

Disorders of Calcium Metabolism

J. Wysolmerski, C. Dumitru, 2013 .

Hypercalcemia of malignancy due to ectopic transactivation of the parathyroid hormone gene.

D. Rimm, A. Arnold, J. Wysolmerski, 2006, The Journal of clinical endocrinology and metabolism.

Calcium-Sensing Receptor in Breast Physiology and Cancer

J. Wysolmerski, Won Ho Kim, Wonnam Kim, 2016, Front. Physiol..

NHERF1 is Required for Localization of PMCA2 and Suppression of Early Involution in the Female Lactating Mammary Gland.

P. A. Friedman, J. Wysolmerski, P. Dann, 2019, Endocrinology.

Adipocyte hypertrophy and lipid dynamics underlie mammary gland remodeling after lactation

V. Seewaldt, J. Wysolmerski, S. Kwei, 2018, Nature Communications.

PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer

P. A. Friedman, L. Liotta, V. Espina, 2016, Proceedings of the National Academy of Sciences.

PTHrP induces STAT5 activation, secretory differentiation and accelerates mammary tumor development

J. Wysolmerski, Jungmin Choi, Diego Y. Grinman, 2022, Breast cancer research : BCR.

Parathyroid Hormone-Related Protein Specifies the Mammary Mesenchyme and Regulates Embryonic Mammary Development

J. Wysolmerski, M. Hiremath, 2013, Journal of Mammary Gland Biology and Neoplasia.

Abstract P3-05-05: PTHrP affects breast cancer initiation and progression through Stat5 signaling pathway

J. Wysolmerski, P. Dann, Kata Boras-Granic, 2017 .

TOPGAL Mice Show That the Canonical Wnt Signaling Pathway Is Active During Bone Development and Growth and Is Activated by Mechanical Loading In Vitro

J. Wysolmerski, M. Horowitz, P. Dann, 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Parathyroid hormone-related protein maintains mammary epithelial fate and triggers nipple skin differentiation during embryonic breast development.

D. Rimm, J. Foley, J. Wysolmerski, 2001, Development.

Analysis of gene expression in PTHrP−/− mammary buds supports a role for BMP signaling and MMP2 in the initiation of ductal morphogenesis

Tien-chi Pan, L. Chodosh, J. Wysolmerski, 2009, Developmental dynamics : an official publication of the American Association of Anatomists.

The calcium-sensing receptor regulates mammary gland parathyroid hormone-related protein production and calcium transport.

M. Neville, E. Brown, J. Wysolmerski, 2004, The Journal of clinical investigation.

Characterization of the Six1 homeobox gene in normal mammary gland morphogenesis

H. Ford, J. McManaman, J. Wysolmerski, 2010, BMC Developmental Biology.

Chapter 64 – Hypercalcemia of Malignancy

J. Wysolmerski, Karena L. Swan, K. Swan, 2016 .

BMP4 and PTHrP interact to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction

G. Robinson, J. Wysolmerski, S. Harris, 2007, Development.

The scaffolding protein NHERF1 regulates the stability and activity of the tyrosine kinase HER2

P. A. Friedman, J. Wysolmerski, Jungmin Choi, 2017, The Journal of Biological Chemistry.

Hypercalcemia in Breast Cancer: An Echo of Bone Mobilization During Lactation?

J. Wysolmerski, Samantha DeMauro, 2005, Journal of Mammary Gland Biology and Neoplasia.

PMCA2 regulates apoptosis during mammary gland involution and predicts outcome in breast cancer

D. Rimm, R. Camp, G. Chung, 2010, Proceedings of the National Academy of Sciences.

Transcellular Calcium Transport in Mammary Epithelial Cells

J. Wysolmerski, J. Vanhouten, 2007, Journal of Mammary Gland Biology and Neoplasia.

Role of PTHrP in Mammary Gland Development and Breast Cancer

J. Wysolmerski, M. Hiremath, 2014, Clinical Reviews in Bone and Mineral Metabolism.

Adipocyte hypertrophy and lipid dynamics underlie mammary gland remodeling after lactation

V. Seewaldt, J. Wysolmerski, S. Kwei, 2018, Nature Communications.

Increased PTHrP and decreased estrogens alter bone turnover but do not reproduce the full effects of lactation on the skeleton.

J. Wysolmerski, P. Dann, J. Vanhouten, 2010, Endocrinology.

Wnt signaling in breast organogenesis

J. Wysolmerski, Kata Boras-Granic, 2008, Organogenesis.

Transactivation of the PTHrP gene in squamous carcinomas predicts the occurrence of hypercalcemia in athymic mice.

J. Foley, J. Wysolmerski, A. Broadus, 1996, Cancer research.

PTHrP induces STAT5 activation, secretory differentiation and accelerates mammary tumor development

J. Wysolmerski, Jungmin Choi, Diego Y. Grinman, 2022, Breast cancer research : BCR.

Embryonic cells contribute directly to the quiescent stem cell population in the adult mouse mammary gland

J. Wysolmerski, P. Dann, Kata Boras-Granic, 2014, Breast Cancer Research.

MAL2 mediates the formation of stable HER2 signaling complexes within lipid raft-rich membrane protrusions in breast cancer cells

J. Wysolmerski, Yansheng Liu, Jaechul Lim, 2021, Cell reports.

Intracellular Calcium links Milk Stasis to Lysosome Dependent Cell Death by Activating a TGFβ3/TFEB/STAT3 Pathway Early during Mammary Gland Involution

J. Wysolmerski, Diana Athonvarangkul, S. Ferguson, 2023, bioRxiv.

PTHrP and breast cancer: more than hypercalcemia and bone metastases

J. Wysolmerski, Kata Boras-Granic, 2012, Breast Cancer Research.

Posttransplant bone disease: evidence for a high bone resorption state.

A. Kliger, J. Wysolmerski, G. Basadonna, 2000, Transplantation.

Mammary-specific ablation of the calcium-sensing receptor during lactation alters maternal calcium metabolism, milk calcium transport, and neonatal calcium accrual.

R. Mamillapalli, J. Wysolmerski, D. Bikle, 2013, Endocrinology.

A Case of Hypercalcemia from PTHrP-Producing Fibromyxoid Sarcoma Responsive to Glucocorticoid Therapy

E. Hsiao, U. Masharani, J. Wysolmerski, 2023, Calcified Tissue International.

Parathyroid Hormone-Related Protein (PTHrP)

J. Wysolmerski, J. V. Houten, 2003 .

Chapter 64 – Hypercalcemia of Malignancy

J. Wysolmerski, K. Swan, 2016 .

Analysis of gene expression in PTHrP−/− mammary buds supports a role for BMP signaling and MMP2 in the initiation of ductal morphogenesis

Tien-chi Pan, L. Chodosh, J. Wysolmerski, 2009, Developmental dynamics : an official publication of the American Association of Anatomists.

Parathyroid hormone-related protein: from hypercalcemia of malignancy to developmental regulatory molecule.

J. Wysolmerski, A. Broadus, M. Dunbar, 1996, The American journal of the medical sciences.

Parathyroid Hormone-related Protein Gene Expression in Human Squamous Carcinoma Cells Is Repressed by Mutant Isoforms of p53'

J. Wysolmerski, A. Broadus, J. Foley, 2006 .