J. Remack

发表

Wild-type p53 suppresses transcription of the human O6-methylguanine-DNA methyltransferase gene.

P. Houghton, L. Harris, J. Remack, 1996, Cancer research.

Development of a Tumor-Selective Approach to Treat Metastatic Cancer

P. Potter, M. Danks, J. Remack, 2006, PloS one.

Evidence for nucleotide excision repair as a modifying factor of O6-methylguanine-DNA methyltransferase-mediated innate chloroethylnitrosourea resistance in human tumor cell lines.

J. Remack, T. Brent, A. McQuillan, 1997, Molecular pharmacology.

Cytoplasmic sequestration of an O6-methylguanine-DNA methyltransferase enhancer binding protein in DNA repair-deficient human cells.

L. Harris, J. Remack, T. Brent, 1997, Proceedings of the National Academy of Sciences of the United States of America.

1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(methylamino)carbonyl]hydrazine (VNP40101M): I. Direct inhibition of O6-alkylguanine-DNA alkyltransferase (AGT) by electrophilic species generated by decomposition

A. Sartorelli, J. Remack, T. Brent, 2004, Cancer Chemotherapy and Pharmacology.

The origin of O6-methylguanine-DNA methyltransferase in Chinese hamster ovary cells transfected with human DNA.

J. Remack, T. Brent, S. Mitra, 1991, Mutation research.

Ribozyme-mediated modulation of human O6-methylguanine-DNA methyltransferase expression.

P. Potter, L. Harris, J. Remack, 1993, Cancer research.

Advances in Brief A Comparison of Human O 6-Methylguanine-DNA Methyltransferase Promoter Activity in Mer + and Mer ~ Cells 1

L. Harris, J. Remack, T. Brent, 2006 .

Changes in O6-methylguanine-DNA methyltransferase expression during immortalization of cloned human fibroblasts.

L. Harris, J. Remack, T. Brent, 1996, Carcinogenesis.

Extraneuronal monoamine transporter expression and DNA repair vis-à-vis 2-chloroethyl-3-sarcosinamide-1-nitrosourea cytotoxicity in human tumor cell lines.

J. Remack, T. Brent, Z. P. Chen, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Development of an etoposide prodrug for dual prodrug-enzyme antitumor therapy

P. Potter, M. Danks, J. Remack, 2006, Molecular Cancer Therapeutics.

Formation of covalent complexes between human O6-alkylguanine-DNA alkyltransferase and BCNU-treated defined length synthetic oligodeoxynucleotides.

J. Remack, T. Brent, 1988, Nucleic acids research.

Evidence that O6-alkylguanine-DNA alkyltransferase becomes covalently bound to DNA containing 1,3-bis(2-chloroethyl)-1-nitrosourea-induced precursors of interstrand cross-links.

J. Remack, T. Brent, D. G. Smith, 1987, Biochemical and biophysical research communications.

Formation of DNA interstrand cross-links by the novel chloroethylating agent 2-chloroethyl(methylsulfonyl)methanesulfonate: suppression by O6-alkylguanine-DNA alkyltransferase purified from human leukemic lymphoblasts.

J. Remack, T. Brent, S. Lestrud, 1987, Cancer research.

In vitro methylation of the human O6-methylguanine-DNA methyltransferase promoter reduces transcription.

L. Harris, J. Remack, T. Brent, 1994, Biochimica et biophysica acta.

Characterization of a novel reaction by human O6-alkylguanine-DNA alkyltransferase with 1,3-bis(2-chloroethyl)-1-nitrosourea-treated DNA.

J. Remack, T. Brent, D. G. Smith, 1987, Cancer research.

1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(methylamino)carbonyl]hydrazine (VNP40101M): II. Role of O6-alkylguanine-DNA alkyltransferase in cytotoxicity

A. Sartorelli, J. Remack, T. Brent, 2004, Cancer Chemotherapy and Pharmacology.

A comparison of human O6-methylguanine-DNA methyltransferase promoter activity in Mer+ and Mer- cells.

P. Potter, L. Harris, J. Remack, 1992, Cancer research.

Identification of a 59 bp enhancer located at the first exon/intron boundary of the human O6-methylguanine DNA methyltransferase gene.

L. Harris, J. Remack, T. Brent, 1994, Nucleic acids research.

Tumor-targeted enzyme/prodrug therapy mediates long-term disease-free survival of mice bearing disseminated neuroblastoma.

M. Wierdl, L. Tsurkan, P. Potter, 2007, Cancer research.

ICAM-2 Expression Mediates a Membrane-Actin Link, Confers a Nonmetastatic Phenotype and Reflects Favorable Tumor Stage or Histology in Neuroblastoma

J. Remack, J. Khoury, D. Phelps, 2008, PloS one.

A specific CpG methylation pattern of the MGMT promoter region associated with reduced MGMT expression in primary colorectal cancers

P. Goodfellow, J. Remack, T. Brent, 1999, Molecular carcinogenesis.

Heterogeneous methylation of the O(6)-methylguanine-DNA methyltransferase promoter in immortalized IMR90 cell lines.

J. Remack, T. Brent, S. Howell, 2001, International journal of oncology.