J. McLachlan

K. Nelson, J. McLachlan, M. P. Walker, 1994, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

DDT and its metabolites alter gene expression in human uterine cell lines through estrogen receptor-independent mechanisms.

J. McLachlan, M. Burow, T. Chiang, 2002, Environmental health perspectives.

Activation of human monocytes by the pineal hormone melatonin.

J. McLachlan, C. Serkin, K. Morrey, 1994, Journal of immunology.

Proliferative lesions and reproductive tract tumors in male descendants of mice exposed developmentally to diethylstilbestrol.

J. Haseman, J. McLachlan, R. Newbold, 2000, Carcinogenesis.

Neonatal diethylstilbestrol exposure induces persistent elevation of c‐fos expression and hypomethylation in its exon‐4 in mouse uterus

J. McLachlan, B. Davis, J. Barrett, 2003, Molecular carcinogenesis.

The Organochlorine o,p’-DDT Plays a Role in Coactivator-Mediated MAPK Crosstalk in MCF-7 Breast Cancer Cells

K. Nephew, J. McLachlan, M. Burow, 2012, Environmental health perspectives.

Gene imprinting in developmental toxicology: a possible interface between physiology and pathology.

J. McLachlan, T. Chiang, S. Li, 2001, Toxicology letters.

The role of estrogen in turtle sex determination and the effect of PCBs.

J. McLachlan, D. Crews, J. Bergeron, 1995, Environmental health perspectives.

Aneuploidy induction and cell transformation by diethylstilbestrol: a possible chromosomal mechanism in carcinogenesis.

J. Barrett, J. McLachlan, T. Tsutsui, 1983, Cancer research.

Green fluorescent protein (GFP) as a marker of aryl hydrocarbon receptor (AhR) function in developing zebrafish (Danio rerio).

C. Mattingly, J. McLachlan, W. A. Toscano, 2001, Environmental health perspectives.

Proliferation and differentiation of mouse uterine epithelial cells in primary serum-free culture: Estradiol-17β suppresses uterine epithelial proliferation cultured on a basement membrane-like substratum

J. McLachlan, H. Fukamachi, J. Mclachlan, 1991, In Vitro Cellular & Developmental Biology - Animal.

Estrogenic effect on the expression of estrogen receptor, COUP‐TF, and lactoferrin mRNA in developing mouse tissues

J. McLachlan, R. Newbold, C. Teng, 1996, Molecular reproduction and development.

Symbiotic Gene Activation is Interrupted by Endocrine Disrupting Chemicals

J. McLachlan, M. Burow, J. Fox, 2001, TheScientificWorldJournal.

Experimental evaluation of vitellogenin as a predictive biomarker for reproductive disruption.

J. McLachlan, M. Brouwer, T. H. Brouwer, 2001, Environmental health perspectives.

Cooxidation of steroidal and non-steroidal estrogens by purified prostaglandin synthase results in a stimulation of prostaglandin formation.

J. McLachlan, T. Eling, G. Degen, 1987, Journal of steroid biochemistry.

Interaction of PAHs and PCBs with ecdysone-dependent gene expression and cell proliferation.

J. McLachlan, E. Oberdörster, D. M. Cottam, 1999, Toxicology and applied pharmacology.

o,p′-DDT and its metabolites inhibit progesterone-dependent responses in yeast and human cells

J. McLachlan, S. F. Arnold, D. M. Klotz, 1997, Molecular and Cellular Endocrinology.

Prenatal diethylstilbestrol exposure alters murine uterine responses to prepubertal estrogen stimulation.

J. McLachlan, R. Newbold, D. Maier, 1985, Endocrinology.

Developmental estrogenization and prostatic neoplasia

J. McLachlan, L. Pylkkänen, S. Mäkelä, 1994, The Prostate.

Human Endometrial Transforming Growth Factor-α: A Transmembrane, Surface Epithelial Protein That Transiently Disappears During the Midsecretory Phase of the Menstrual Cycle

R. Bentley, J. McLachlan, D. Walmer, 1997, Journal of the Society for Gynecologic Investigation.

p53lyn and p56lyn: A New Signaling Pathway in Human Endometrium and Endometrial Adenocarcinomas

M. Tsao, J. McLachlan, D. Walmer, 1997, The Journal of the Society for Gynecologic Investigation: JSGI.

Mutations of the Ki-ras oncogene in endometrial carcinoma.

A. Berchuck, J. Boyd, J. McLachlan, 1992, American journal of obstetrics and gynecology.

Characterization of murine cell lines from Diethylstilbestrol-Induced uterine endometrial Adenocarcinomas

J. Barrett, K. Korach, J. McLachlan, 1992, In Vitro Cellular & Developmental Biology - Animal.

Environmental hormones : the scientific basis of endocrine disruption

J. McLachlan, 2001 .

Indirect evidence for the metabolic dehalogenation of tetrafluorodiethylstilbestrol by rat and hamster liver and kidney microsomes. Species- and organ-dependent differences.

M. Metzler, J. McLachlan, M. M. Hey, 1986, Biochemical pharmacology.

Non-estrogenic metabolites of diethylstilbestrol produced by prostaglandin synthase mediated metabolism

J. McLachlan, G. Degen, 1983, Steroids.

Oxidative metabolism of diethylstilbestrol by prostaglandin synthetase.

J. McLachlan, T. Eling, G. Degen, 1982, Cancer research.

Detoxification of polychlorinated biphenyls

K. Korach, J. McLachlan, J. Mckinney, 1990, The Lancet.

Estrogen‐Associated Genes in Uterine Leiomyoma

J. McLachlan, Shuanfang Li, J. Mclachlan, 2001, Annals of the New York Academy of Sciences.

Environmental hormones and the male reproductive system.

J. McLachlan, A. Cheek, John A. McLachlan, 1998, Journal of andrology.

Testicular tumors in mice exposed in utero to diethylstilbestrol.

J. McLachlan, R. Newbold, B. Bullock, 1987, The Journal of urology.

Synergistic signals in the environment.

J. McLachlan, S. F. Arnold, 1996, Environmental health perspectives.

Benthic Community Structure and Biomarker Induction in Grass Shrimp in an Estuarine System

J. McLachlan, E. Oberdörster, M. Martín, 1999, Archives of environmental contamination and toxicology.

Evaluation of the estrogenic effects of legume extracts containing phytoestrogens.

T. Cleveland, J. McLachlan, S. Elliott, 2003, Journal of agricultural and food chemistry.

Effects of estrogen on leptin gene promoter activation in MCF-7 breast cancer and JEG-3 choriocarcinoma cells: selective regulation via estrogen receptors alpha and beta.

J. McLachlan, M. C. Henson, M. Burow, 2001, Molecular and cellular endocrinology.

Dietary intervention study to assess estrogenicity of dietary soy among postmenopausal women.

C. Weinberg, A. Wilcox, D. Baird, 1995, The Journal of clinical endocrinology and metabolism.

Endocrine disruption in sexual differentiation and puberty. What do pseudohermaphroditic polar bears have to do with the practice of pediatrics?

J. McLachlan, M. Burow, C. C. Gulledge, 2001, Pediatric clinics of North America.

Effects of environmental estrogens on tumor necrosis factor α-mediated apoptosis in MCF-7 cells

Yan Tang, John Calvin Reed, S. Krajewski, 1999 .

Peptide growth factors elicit estrogen receptor-dependent transcriptional activation of an estrogen-responsive element.

K. Korach, J. McLachlan, M. Parker, 1993, Molecular endocrinology.

Immunological functions of aged human monocytes.

J. McLachlan, C. Serkin, O. Bakouche, 1995, Pathobiology : journal of immunopathology, molecular and cellular biology.

, Florastina ) max GlycineIdentification of the Potent Phytoestrogen Glycinol in Elicited Soybean

Allen P. Miraflor, T. Cleveland, J. McLachlan, 2009 .

Long-term pyrene exposure of grass shrimp, Palaemonetes pugio, affects molting and reproduction of exposed males and offspring of exposed females.

J. McLachlan, E. Oberdörster, M. Brouwer, 2000, Environmental health perspectives.

Techniques for detection of estrogenicity.

K. Korach, J. McLachlan, K. S. Korach, 1995, Environmental health perspectives.

Synergism in estrogen-regulated gene expression

J. McLachlan, S. F. Arnold, D. M. Klotz, 1996, Molecular and Cellular Endocrinology.

Flavonoid phytochemicals regulate activator protein-1 signal transduction pathways in endometrial and kidney stable cell lines.

J. McLachlan, B. Collins-Burow, M. Burow, 2002, The Journal of nutrition.

Prenatal exposure to diethylstilbestrol in mice: toxicological studies.

J. McLachlan, J. Mclachlan, 1977, Journal of toxicology and environmental health.

Molecular feminization of mouse seminal vesicle by prenatal exposure to diethylstilbestrol: altered expression of messenger RNA.

J. McLachlan, R. Newbold, C. Teng, 1994, The Journal of urology.

Transforming growth factors beta 1, beta 2, and beta 3 messenger RNA and protein expression in mouse uterus and vagina during estrogen-induced growth: a comparison to other estrogen-regulated genes.

K. Flanders, K. Nelson, J. McLachlan, 1994, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Estrogens in the Environment

J. McLachlan, 1980 .

Bisphenol A alters the self-renewal and differentiation capacity of human bone-marrow-derived mesenchymal stem cells

J. Glowacki, K. Nephew, J. McLachlan, 2016 .

Bisphenol A enhances adipogenic differentiation of human adipose stromal/stem cells.

J. Gimble, Jason F. Ohlstein, J. McLachlan, 2014, Journal of molecular endocrinology.

The fate of diethylstilbestrol in the pregnant mouse.

J. McLachlan, H. C. Shah, J. Mclachlan, 1976, The Journal of pharmacology and experimental therapeutics.

Inhibition of 17 beta-estradiol and progesterone activity in human breast and endometrial cancer cells by carbamate insecticides.

J. McLachlan, S. F. Arnold, D. M. Klotz, 1997, Life sciences.

p38 mitogen-activated protein kinase stimulates estrogen-mediated transcription and proliferation through the phosphorylation and potentiation of the p160 coactivator glucocorticoid receptor-interacting protein 1.

T. Curiel, J. McLachlan, P. Kushner, 2006, Molecular endocrinology.

Differential interaction of natural and synthetic estrogens with extracellular binding proteins in a yeast estrogen screen

J. McLachlan, L. Guillette, M. Robinson, 1996, Steroids.

Common phytochemicals are ecdysteroid agonists and antagonists: a possible evolutionary link between vertebrate and invertebrate steroid hormones

J. McLachlan, E. Oberdörster, D. M. Cottam, 2001, The Journal of Steroid Biochemistry and Molecular Biology.

Cross-talk between Phosphatidylinositol 3-Kinase and Sphingomyelinase Pathways as a Mechanism for Cell Survival/Death Decisions*

A. Klippel, J. McLachlan, B. Collins-Burow, 2000, The Journal of Biological Chemistry.

Long-term effects on the female mouse genital tract associated with prenatal exposure to diethylstilbestrol.

J. McLachlan, R. Newbold, B. Bullock, 1980, Cancer research.

Phytochemical Glyceollins, Isolated from Soy, Mediate Antihormonal Effects through Estrogen Receptor α and β1

T. Cleveland, J. McLachlan, B. Collins-Burow, 2001 .

The estrogenic and antiestrogenic activities of phytochemicals with the human estrogen receptor expressed in yeast

J. McLachlan, S. F. Arnold, B. M. Collins, 1997, Steroids.

Phytoestrogens are partial estrogen agonists in the adult male mouse.

J. McLachlan, S. Mäkelä, R. Santti, 1995, Environmental health perspectives.

From malformations to molecular mechanisms in the male: three decades of research on endocrine disrupters

J. McLachlan, R. Newbold, S. Li, 2001, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

Regional differences in the prostate of the neonatally estrogenized mouse

J. McLachlan, L. Pylkkänen, R. Newbold, 1991, The Prostate.

Female gene expression in the seminal vesicle of mice after prenatal exposure to diethylstilbestrol.

J. V. Miller, S. Yamashita, J. McLachlan, 1989, Endocrinology.

Androgen metabolism in control and neonatally estrogenized male mice.

J. McLachlan, R. Newbold, R. Santti, 1991, Reproductive toxicology.

AKT Regulation of Estrogen Receptor β Transcriptional Activity in Breast Cancer

J. Alam, J. McLachlan, O. David, 2006 .

Exposure to diethylstilbestrol during a critical developmental period of the mouse reproductive tract leads to persistent induction of two estrogen-regulated genes.

K. Nelson, J. McLachlan, Y. Sakai, 1994, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Environmental hormones: Multiple pathways for response may lead to multiple disease outcomes

J. McLachlan, M. Burow, Syreeta L. Tilghman, 2010, Steroids.

Identification of the potent phytoestrogen glycinol in elicited soybean (Glycine max).

Allen P. Miraflor, T. Cleveland, J. McLachlan, 2009, Endocrinology.

Effects of environmental estrogens on tumor necrosis factor alpha-mediated apoptosis in MCF-7 cells.

John Calvin Reed, S. Krajewski, J. McLachlan, 1999, Carcinogenesis.

Estrogenic and antiestrogenic activities of phytoalexins from red kidney bean (Phaseolus vulgaris L.).

D. Bhatnagar, J. McLachlan, S. Elliott, 2011, Journal of agricultural and food chemistry.

PI3-K/AKT regulation of NF-kappaB signaling events in suppression of TNF-induced apoptosis.

J. McLachlan, B. Collins-Burow, M. Burow, 2000, Biochemical and biophysical research communications.

Air, water, soil and environmental signaling.

J. McLachlan, H. Mielke, J. Mclachlan, 2020, Current problems in pediatric and adolescent health care.

The androgen-dependent mouse seminal vesicle secretory protein IV: characterization and complementary deoxyribonucleic acid cloning.

J. McLachlan, C. Teng, B. Pentecost, 1987, Molecular endocrinology.

Epidermal growth factor binding and receptor distribution in the mouse reproductive tract during development.

K. Nelson, J. McLachlan, N. Bossert, 1990, Developmental biology.

Catechol estrogen formation in mouse uterus.

J. McLachlan, C. Bunyagidj, J. Mclachlan, 1988, Journal of steroid biochemistry.

Fluctuations of lactoferrin protein and messenger ribonucleic acid in the reproductive tract of the mouse during the estrous cycle.

J. V. Miller, J. McLachlan, R. Newbold, 1992, Biology of reproduction.

Phytoestrogen signaling and symbiotic gene activation are disrupted by endocrine-disrupting chemicals.

J. McLachlan, M. Burow, J. Fox, 2004, Environmental health perspectives.

Report, 290: Male reproductive health and environmental chemicals with estrogenic effects

N. Keiding, R. Sharpe, J. Toppari, 1995 .

Immunodetection of estrogen receptor in epithelial and stromal tissues of neonatal mouse uterus.

K. Korach, J. McLachlan, R. Newbold, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Peroxidase-mediated in vitro metabolism of diethylstilbestrol and structural analogs with different biological activities.

J. McLachlan, G. Degen, J. Mclachlan, 1985, Chemico-biological interactions.

Reduced fertility in female mice exposed transplacentally to diethylstilbestrol (DES).

M. D. Hogan, J. McLachlan, R. Newbold, 1982, Fertility and sterility.

Prenatal exposure of male mice to diethylstilbestrol alter the expression of the lactotransferrin gene in seminal vesicles.

J. McLachlan, R. Newbold, C. Teng, 1988, Molecular endocrinology.

Xenobiotic-induced TNF-α expression and apoptosis through the p38 MAPK signaling pathway

J. McLachlan, S. Elliott, M. Burow, 2005 .

Alteration in diethylstilbestrol-induced mutagenicity and cell transformation by exogenous metabolic activation.

J. Barrett, J. McLachlan, N. Suzuki, 1986, Carcinogenesis.

Diethylstilbestrol induces neoplastic transformation without measurable gene mutation at two loci.

J. Barrett, J. McLachlan, A. Wong, 1981, Science.

Müllerian duct maintenance in heterotypic organ culture after in vivo exposure to diethylstilbestrol.

J. McLachlan, R. Newbold, Y. Suzuki, 1984, Endocrinology.

Developmental pattern of estrogen receptor expression in female mouse genital tracts.

K. Korach, J. McLachlan, R. Newbold, 1989, Endocrinology.

Dehydroepiandrosterone modulation of lipopolysaccharide-stimulated monocyte cytotoxicity.

J. McLachlan, C. Serkin, O. Bakouche, 1996, Journal of immunology.

Glyceollin I, a Novel Antiestrogenic Phytoalexin Isolated from Activated Soy

M. Lacey, T. Cleveland, J. McLachlan, 2010, Journal of Pharmacology and Experimental Therapeutics.

Coordinate regulation by diethylstilbestrol of the platelet-derived growth factor-A (PDGF-A) and -B chains and the PDGF receptor alpha- and beta-subunits in the mouse uterus and vagina: potential mediators of estrogen action.

J. McLachlan, K. Gray, K. Raszmann, 1995, Endocrinology.

Nitrogen fixation: Endocrine disrupters and flavonoid signalling

J. McLachlan, M. Burow, J. Fox, 2001, Nature.

17beta-Estradiol-induced cell transformation and aneuploidy of Syrian hamster embryo cells in culture.

J. Barrett, J. McLachlan, N. Suzuki, 1987, Carcinogenesis.

Microsoft Word-68398447-file00

M. Lacey, T. Cleveland, J. McLachlan, 2009 .

Potentiation of diethylstilbestrol‐induced alterations in the female mouse reproductive tract by transforming growth factor‐α transgene expression

G. Merlino, R. Dickson, J. McLachlan, 1996, Molecular carcinogenesis.

Antitumoral properties of aged human monocytes.

J. McLachlan, C. Serkin, K. Morrey, 1995, Journal of immunology.

Analysis of messenger ribonucleic acid and protein for the ligands and receptors of the platelet-derived growth factor signaling pathway in the placenta, extraembryonic membranes, and uterus during the latter half of murine gestation.

J. McLachlan, D. Walmer, B. Eitzman, 1995, Endocrinology.

From malformations to molecular mechanisms in the male: three decades of research on endocrine disrupters Note

J. McLachlan, M. Burow, R. Newbold, 2001 .

Developmentally arrested oviduct: a structural and functional defect in mice following prenatal exposure to diethylstilbestrol.

J. McLachlan, R. Newbold, A. Haney, 1983, Teratology.

Alteration of Leopard Frog (Rana pipiens) Metamorphosis by the Herbicide Acetochlor

J. Bollinger, J. McLachlan, C. Rider, 1999, Archives of environmental contamination and toxicology.

Estrogens and development.

J. McLachlan, R. Newbold, J. Mclachlan, 1987, Environmental health perspectives.

Characteristics of estrogen-induced peroxidase in mouse uterine luminal fluid

J. McLachlan, P. Jellinck, R. NewboldRetha, 1991, Steroids.

Molecular characterization of a testis-specific estrogen sulfotransferase and aberrant liver expression in obese and diabetogenic C57BL/KsJ-db/db mice.

J. McLachlan, M. Negishi, R. Moore, 1995, Endocrinology.

Estrogen‐induced cell transformation and DNA adduct formation in cultured Syrian hamster embryo cells

J. Barrett, J. McLachlan, T. Tsutsui, 1996, Molecular carcinogenesis.

Dependence on exogenous metabolic activation for induction of unscheduled DNA synthesis in Syrian hamster embryo cells by diethylstilbestrol and related compounds.

J. Barrett, D. Schiffmann, J. McLachlan, 1984, Cancer research.

Diethylstilbestrol metabolism by the fetal genital tract.

M. Metzler, J. McLachlan, R. Newbold, 1983, Endocrinology.

Imposex in the intertidal snail Thais brevidentata (Gastropoda: Muricidae) from the Pacific coast of Costa Rica

J. McLachlan, P. Gravel, E. Oberdörster, 2006 .

p53 gene mutations in human endometrial carcinoma

J. Boyd, M. Tsao, J. McLachlan, 1992, Molecular carcinogenesis.

Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure.

Shuk-Mei Ho, Taisen Iguchi, Laura N. Vandenberg, 2007, Reproductive toxicology.

Antiestrogenic Glyceollins Suppress Human Breast and Ovarian Carcinoma Tumorigenesis

T. Curiel, T. Cleveland, J. McLachlan, 2006, Clinical Cancer Research.

Hazardous materials in aquatic environments of the Mississippi River Basin Project management. Technical quarterly progress report, April 1, 1996--June 30, 1996

J. McLachlan, C. Ide, S. OConnor, 1996 .

Chemical exposure of embryos during the preimplantation stages of pregnancy: mortality rate and intrauterine development.

J. McLachlan, S. Fabro, N. M. Dames, 1984, American journal of obstetrics and gynecology.

The Biology of Lymnaea peregra (Muller) (Gastropoda:Pulmonata: Basommatophora) with Special Reference to the Effects of Herbicides on its Reproduction

J. McLachlan, R. Port, .. M.NazrulIslam, 2001 .

In vitro molecular mechanisms of bisphenol A action.

Cheryl S Watson, Carlos Sonnenschein, Jun Kanno, 2007, Reproductive toxicology.

Reproductive tract lesions in male mice exposed prenatally to diethylstilbestrol

J. McLachlan, R. Newbold, B. Bullock, 1975, Science.

Environmental signaling: what embryos and evolution teach us about endocrine disrupting chemicals.

J. McLachlan, J. Mclachlan, 2001, Endocrine reviews.

Estrogenic and Antiestrogenic Activities of FlavonoidPhytochemicals Through Estrogen ReceptorBinding-Dependent and -Independent Mechanisms

J. McLachlan, B. Collins-Burow, M. Burow, 2000, Nutrition and cancer.

Potential mechanisms of thyroid disruption in humans: interaction of organochlorine compounds with thyroid receptor, transthyretin, and thyroid-binding globulin.

J. McLachlan, A. Cheek, Kelvin Y. Kow, 1999, Environmental health perspectives.

Adenocarcinoma of the rete testis. Diethylstilbestrol-induced lesions of the mouse rete testis.

J. McLachlan, R. Newbold, B. Bullock, 1986, The American journal of pathology.

Cellular Bioavailability of Natural Hormones and Environmental Contaminants as a Function of Serum and Cytosolic Binding Factors

J. McLachlan, L. Guillette, N. Noriega, 1998, Toxicology and industrial health.

Uterine adenocarcinoma in mice following developmental treatment with estrogens: a model for hormonal carcinogenesis.

J. McLachlan, R. Newbold, B. Bullock, 1990, Cancer research.

Mycotoxins as estrogens.

J. McLachlan, C. J. Mirocha, S. Pathre, 1980 .

Hormone-Dependent Uterine Adenocarcinoma Following Developmental Treatment with Diethylstilbestrol: A Murine Model for Hormonal Carcinogenesis

J. McLachlan, R. Newbold, B. Bullock, 1992 .

Peptide growth factor cross-talk with the estrogen receptor requires the A/B domain and occurs independently of protein kinase C or estradiol.

K. Korach, J. McLachlan, M. Parker, 1996, Endocrinology.

Lesions of testis and epididymis associated with prenatal diethylstilbestrol exposure.

J. McLachlan, R. Newbold, B. Bullock, 1988, Environmental health perspectives.

SynthetaseMetabolism of Diethylstilbestrol by Prostaglandin

J. McLachlan, T. Eling, G. Degen, 2013 .

Oxidative metabolites of diethylstilbestrol in the fetal, neonatal and adult mouse.

M. Metzler, J. McLachlan, J. Mclachlan, 1978, Biochemical pharmacology.

Paraovarian cysts associated with prenatal diethylstilbestrol exposure. Comparison of the human with a mouse model.

J. McLachlan, R. Newbold, A. Haney, 1986, The American journal of pathology.

Comparison of theHumanWith a MouseModel

J. McLachlan, R. Newbold, A. Haney, 1986 .

Antiestrogenic activity of flavonoid phytochemicals mediated via the c-Jun N-terminal protein kinase pathway. Cell-type specific regulation of estrogen receptor alpha

T. Curiel, J. Alam, J. McLachlan, 2012, The Journal of Steroid Biochemistry and Molecular Biology.

Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing.

L. Giudice, S. Swan, N. Skakkebaek, 2008, Fertility and sterility.

Altered Breast Development in Young Girls from an Agricultural Environment

J. McLachlan, L. Guillette, C. Conard, 2006, Environmental health perspectives.

Diethylstilbestrol metabolites and analogs. New probes for the study of hormone action.

M. Metzler, K. Korach, J. McLachlan, 1979, The Journal of biological chemistry.

Possible role of peroxidase in the diethylstilbestrol-induced lesions of the Syrian hamster kidney.

M. Metzler, J. McLachlan, J. Lamb, 1978, Life sciences.

DNA hypomethylation and imbalanced expression of DNA methyltransferases (DNMT1, 3A, and 3B) in human uterine leiomyoma.

J. Barrett, J. McLachlan, T. Chiang, 2003, Gynecologic oncology.

Phytoalexins, miRNAs and Breast Cancer: A Review of Phytochemical-mediated miRNA Regulation in Breast Cancer

T. Vasaitis, J. McLachlan, L. Rhodes, 2013, Journal of health care for the poor and underserved.

Diethylstilbestrol stimulates persistent phosphatidylinositol lipid turnover by an estrogen receptor-mediated mechanism in immature mouse uterus.

K. Korach, J. Putney, J. McLachlan, 1991, Endocrinology.

Influence of estrogens on mouse uterine epidermal growth factor precursor protein and messenger ribonucleic acid.

K. Korach, G. Bell, J. McLachlan, 1988, Endocrinology.

Regulation of ERα-mediated transcription of Bcl-2 by PI3K-AKT crosstalk: Implications for breast cancer cell survival

J. McLachlan, S. Elliott, M. Burow, 2010 .

Regulation of ERalpha-mediated transcription of Bcl-2 by PI3K-AKT crosstalk: implications for breast cancer cell survival.

J. McLachlan, S. Elliott, M. Burow, 2010, International journal of oncology.

Environmental signaling: from environmental estrogens to endocrine‐disrupting chemicals and beyond

J. McLachlan, J. Mclachlan, 2016, Andrology.

Proliferation of mouse uterine epithelial cells in vitro.

J. McLachlan, Y. Tomooka, R. Diaugustine, 1986, Endocrinology.

Transforming growth factor-alpha is a potential mediator of estrogen action in the mouse uterus.

K. Nelson, J. McLachlan, N. Bossert, 1992, Endocrinology.

Estrogens and Growth Factors in the Development, Growth, and Function of the Female Reproductive Tract

K. Korach, K. Nelson, J. McLachlan, 1991 .

Oestrogen-mediated suppression of tumour necrosis factor alpha-induced apoptosis in MCF-7 cells: subversion of Bcl-2 by anti-oestrogens

Yan Tang, J. McLachlan, M. Burow, 2001, The Journal of Steroid Biochemistry and Molecular Biology.

The role of the estrogen receptor in uterine epithelial proliferation and cytodifferentiation in neonatal mice.

K. Korach, J. McLachlan, R. Newbold, 1990, Endocrinology.

Nonrandom karyotypic changes in immortal and tumorigenic Syrian hamster cells induced by diethylstilbestrol.

J. Barrett, J. McLachlan, M. Oshimura, 1989, Cancer genetics and cytogenetics.

Effect of in utero exposure to diethylstilbestrol on the immune response in mice.

R. Faith, G. Clark, J. McLachlan, 1979, Toxicology and applied pharmacology.

Endocrine disruptors and the tumor microenvironment: A new paradigm in breast cancer biology

J. McLachlan, E. Martin, M. Burow, 2017, Molecular and Cellular Endocrinology.

Control of Uterine Epithelial Growth and Differentiation: Implications for Estrogen-Associated Neoplasia

K. Korach, K. Nelson, J. McLachlan, 1992 .

Coupling of dual signaling pathways: epidermal growth factor action involves the estrogen receptor.

K. Korach, K. Nelson, J. McLachlan, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Altered Postnatal Development Following Intrauterine Exposure to Hormonally Active Chemicals

J. McLachlan, S. Fabro, J. Mclachlan, 1982 .

Molecular differentiation of the mouse genital tract: altered protein synthesis following prenatal exposure to diethylstilbestrol.

J. McLachlan, S. Harris, R. Newbold, 1984, Biology of reproduction.

Developmental oestrogenization and prostatic neoplasia.

J. McLachlan, L. Pylkkänen, R. Santti, 1990, International journal of andrology.

Developmental diethylstilbestrol exposure alters genetic pathways of uterine cytodifferentiation.

J. Vuoristo, J. McLachlan, T. Chiang, 2005, Molecular endocrinology.

Adult human mesenchymal stem cells enhance breast tumorigenesis and promote hormone independence

M. Lacey, R. Pochampally, J. McLachlan, 2010, Breast Cancer Research and Treatment.

PCBs as environmental estrogens: turtle sex determination as a biomarker of environmental contamination.

D Crews, J. McLachlan, D. Crews, 1994, Environmental health perspectives.

Interaction of environmental chemicals with the estrogen and progesterone receptors from the oviduct of the American alligator.

J. McLachlan, L. Guillette, S. F. Arnold, 1996, Environmental health perspectives.

Transplacental effects of diethylstilbestrol in mice.

J. McLachlan, 1979, National Cancer Institute monograph.

Lesions of the rete testis in mice exposed prenatally to diethylstilbestrol.

J. McLachlan, R. Newbold, B. Bullock, 1985, Cancer research.

Prenatal diethylstilbestrol exposure in the mouse: effects on ovarian histology and steroidogenesis in vitro.

J. McLachlan, R. Newbold, A. Haney, 1984, Biology of reproduction.

Identification and characterization of estrogen and progesterone receptors from the oviduct of the American alligator (Alligator mississippiensis).

J. McLachlan, L. Guillette, S. F. Arnold, 1997, Biochemical and biophysical research communications.

The role of the estrogen receptor in diethylstilbestrol toxicity.

K. Korach, J. McLachlan, K S Korach, 1985, Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement.

Mechanism of AP-1-mediated gene expression by select organochlorines through the p38 MAPK pathway.

Yan Tang, J. Alam, J. McLachlan, 2003, Carcinogenesis.

Minireview: Endocrine Disruptors: Past Lessons and Future Directions.

Ana M Soto, Carlos Sonnenschein, Louis J Guillette, 2016, Molecular endocrinology.

Fathead minnow (Pimephales promelas) vitellogenin: purification, characterization and quantitative immunoassay for the detection of estrogenic compounds.

J. McLachlan, L. Parks, S. Heppell, 1999, Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology.

Estrogen receptor-binding activity of polychlorinated hydroxybiphenyls: conformationally restricted structural probes.

K. Chae, K. Korach, J. McLachlan, 1988, Molecular pharmacology.

Age-dependent morphological changes in the seminal colliculus in male mice

J. McLachlan, J. Lamb, Y. Suzuki, 1979, Anatomy and Embryology.

Transitional changes in the surface epithelium of the cycling mouse vagina, cervix and uterus: scanning electron microscopic studies.

J. McLachlan, R. Newbold, W. Stumpf, 1978, Biology of reproduction.

Peroxidase-mediated oxidation, a possible pathway for metabolic activation of diethylstilbestrol.

M. Metzler, J. McLachlan, J. Mclachlan, 1978, Biochemical and biophysical research communications.

Visualization by light and scanning electron microscopy of reproductive tract lesions in female mice treated transplacentally with diethylstilbestrol.

J. McLachlan, R. Newbold, J. Lamb, 1981, Cancer research.

Evaluation of the transplacental toxicity of diethylstilbestrol with the scanning electron microscope.

J. McLachlan, R. Newbold, J. Lamb, 1979, Journal of toxicology and environmental health.

Synergistic responses of steroidal estrogens in vitro (yeast) and in vivo (turtles).

J. McLachlan, D. Crews, W. A. Toscano, 1997, Biochemical and biophysical research communications.

Mouse decay-accelerating factor: selective and tissue-specific induction by estrogen of the gene encoding the glycosylphosphatidylinositol-anchored form.

J. McLachlan, M. Negishi, R. Newbold, 1996, Journal of immunology.

Morphologic and neoplastic transformation of Syrian hamster embryo fibroblasts by diethylstilbestrol and its analogs.

J. Barrett, J. McLachlan, G. Degen, 1982, Cancer research.

Proposed nomenclature for diethylstilbestrol metabolites.

M. Metzler, J. McLachlan, 1978, Journal of environmental pathology and toxicology.

Epigenetics, evolution, endocrine disruption, health, and disease.

J. McLachlan, D. Crews, J. Mclachlan, 2006, Endocrinology.

Environmental Exposure, DNA Methylation, and Gene Regulation

J. C. Barrett, J. McLachlan, B. Davis, 2003 .

Environmental exposure, DNA methylation, and gene regulation: lessons from diethylstilbesterol-induced cancers.

J. Barrett, J. McLachlan, B. Davis, 2003, Annals of the New York Academy of Sciences.

Promoter CpG methylation of Hox‐a10 and Hox‐a11 in mouse uterus not altered upon neonatal diethylstilbestrol exposure *

J. C. Barrett, J. McLachlan, M. Burow, 2001, Molecular carcinogenesis.

Synergistic Activation of Estrogen Receptor with Combinations of Environmental Chemicals

Steven F. Arnold, J. McLachlan, L. Guillette, 1996, Science.

Gαo potentiates estrogen receptor α activity via the ERK signaling pathway.

Yan Tang, S. Hill, J. Alam, 2012, The Journal of endocrinology.

Proteomic analysis of tumor necrosis factor-α resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype

Yan Tang, R. Schiff, W. Xiong, 2008, Breast Cancer Research.

Commentary: prenatal exposure to diethylstilbestrol (DES): a continuing story.

J. McLachlan, J. Mclachlan, 2006, International journal of epidemiology.

Original Article Pharmacology and anti-tumor activity of RWJ67657, a novel inhibitor of p38 mitogen activated protein kinase

J. McLachlan, S. Elliott, M. Burow, 2012 .

Pharmacology and anti-tumor activity of RWJ67657, a novel inhibitor of p38 mitogen activated protein kinase.

J. McLachlan, S. Elliott, M. Burow, 2012, American journal of cancer research.

Estrogenic activity in vivo and in vitro of some diethylstilbestrol metabolites and analogs.

M. Metzler, K. Korach, J. McLachlan, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Alterations in estrogen levels during development affects the skeleton: use of an animal model.

K. Korach, J. McLachlan, R. Newbold, 1995, Environmental health perspectives.

G a potentiates estrogen receptor o a activity via the ERK signaling pathway

Yan Tang, S. Hill, J. Alam, 2012 .

Symposium on estrogens in the environment, III.

K. Korach, J. McLachlan, J. Mclachlan, 1995, Environmental health perspectives.

Children's health and the environment: a new agenda for prevention research.

F P Perera, R A Etzel, W A Suk, 1998, Environmental health perspectives.

Cytogenetic analysis of murine cell lines from diethylstilbestrol-induced uterine endometrial adenocarcinomas.

J. Barrett, J. McLachlan, R. Newbold, 1994, Cancer genetics and cytogenetics.

The Control of Psyehoda Fly in Biological Filters on Sewage Disposal Works.

J. McLachlan, E. Hogg, 1948 .

Pesticides reduce symbiotic efficiency of nitrogen-fixing rhizobia and host plants

J. McLachlan, M. Burow, J. Fox, 2007, Proceedings of the National Academy of Sciences.

Effects of the Endocrine-Disrupting Chemical DDT on Self-Renewal and Differentiation of Human Mesenchymal Stem Cells

K. Nephew, D. Rusch, J. McLachlan, 2014, Environmental health perspectives.

Organochlorine-mediated potentiation of the general coactivator p300 through p38 mitogen-activated protein kinase.

J. McLachlan, M. Burow, M. Bratton, 2008, Carcinogenesis.

Identification of mitogen-activated protein kinase kinase as a chemoresistant pathway in MCF-7 cells by using gene expression microarray.

J. Alam, J. McLachlan, S. Elliott, 2002, Surgery.

Endocrine disrupters and female reproductive health.

J. McLachlan, Melvenia M. Martin, E. Simpson, 2006, Best practice & research. Clinical endocrinology & metabolism.

Progressive proliferative changes in the oviduct of mice following developmental exposure to diethylstilbestrol.

J. McLachlan, R. Newbold, B. Bullock, 1985, Teratogenesis, carcinogenesis, and mutagenesis.

Ecoestrogens and embryos—is there a scientific basis for concern?

J. McLachlan, L. Guillette, S. F. Arnold, 1996 .

Environmental signaling: a biological context for endocrine disruption.

J. McLachlan, E. Oberdörster, E. Oberdorster, 1998, Environmental health perspectives.

Comparison of Short-Term Estrogenicity Tests for Identification of Hormone-Disrupting Chemicals

H. Leffers, J. Sumpter, N. Olea, 1999, Environmental health perspectives.

In vitro synergistic interaction of alligator and human estrogen receptors with combinations of environmental chemicals.

J. McLachlan, L. Guillette, S. F. Arnold, 1997, Environmental health perspectives.

Lactotransferrin gene expression in the mouse uterus and mammary gland.

J. McLachlan, R. Newbold, E. M. Eddy, 1989, Endocrinology.

Müllerian remnants of male mice exposed prenatally to diethylstilbestrol.

J. McLachlan, R. Newbold, B. Bullock, 1987, Teratogenesis, carcinogenesis, and mutagenesis.

AKT regulation of estrogen receptor beta transcriptional activity in breast cancer.

J. Alam, J. McLachlan, O. David, 2006, Cancer research.

PKC-mediated survival signaling in breast carcinoma cells: a role for MEK1-AP1 signaling.

J. McLachlan, B. Collins-Burow, M. Burow, 2005, International journal of oncology.

The pH values of the uterine secretions and preimplantation blastocyst of the rabbit.

J. McLachlan, S. Sieber, S. Fabro, 1970, Fertility and sterility.

Mechanism of diethylstilbestrol carcinogenicity as studied with the fluorinated analogue E-3',3",5',5"-tetrafluorodiethylstilbestrol.

J. McLachlan, J. Liehr, D. Sirbasku, 1983, Cancer research.

A novel fluorinated derivative of diethylstilbestrol

M. Metzler, K. Korach, J. McLachlan, 1979, Steroids.

Diethylstilbestrol metabolic transformation in relation to organ specific tumor manifestation.

M. Metzler, J. McLachlan, 1979, Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement.

Morphological and Neoplastic Transformation of Syrian Hamster Embryo Fibroblasts by Diethylstilbestrol and Its Analogs

J. McLachlan, G. Degen, J. Barrett, 2006 .

Localization of diethylstilbestrol metabolites in the mouse genital tract.

M. Metzler, J. McLachlan, R. Newbold, 1985, Biochemical Pharmacology.

Involvement of prostaglandin synthetase in the peroxidative metabolism of diethylstilbestrol in Syrian hamster embryo fibroblast cell cultures.

J. Barrett, J. McLachlan, T. Eling, 1983, Cancer research.

Is diethylstilbestrol bioactivated through peroxidase-mediated oxidation?

M. Metzler, J. McLachlan, 1978, Journal of Environmental Pathology And Toxicology.

Oxidative metabolism of the synthetic estrogens hexestrol and dienestrol indicates reactive intermediates.

M. Metzler, J. McLachlan, 1981, Advances in experimental medicine and biology.

Molecular structures of metabolites and analogues of diethylstilbestrol and their relationship to receptor binding and biological activity.

M. Metzler, K. Korach, J. McLachlan, 1984, Molecular pharmacology.

Ontogeny of peroxidase activity in epithelium and eosinophils of the mouse uterus.

M. Metzler, J. McLachlan, R. Newbold, 1991, Teratogenesis, carcinogenesis, and mutagenesis.

Diethylstilbestrol and Other Estrogens in the Environment

K. Korach, J. McLachlan, R. Newbold, 1984 .

Diethylstilbestrol and other estrogens in the environment.

K. Korach, J. McLachlan, R. Newbold, 1984, Fundamental and applied toxicology : official journal of the Society of Toxicology.

Commentary: Children's Health and the Environment: A New Agenda for Prevention Research

F. Perera, R. Bullard, R. Etzel, 1998 .

Why Public Health Agencies Cannot Depend on Good Laboratory Practices as a Criterion for Selecting Data: The Case of Bisphenol A

Koji Arizono, Taisen Iguchi, Laura N. Vandenberg, 2008, Environmental health perspectives.

Cross talk between peptide growth factor and estrogen receptor signaling systems.

K. Korach, J. McLachlan, C. Teng, 1995, Environmental health perspectives.

Malignant transformation of the human endometrium is associated with overexpression of lactoferrin messenger RNA and protein.

R. Bentley, M. Tsao, J. McLachlan, 1995, Cancer research.

Purification and properties of an oestrogen-stimulated mouse uterine glycoprotein (approx. 70 kDa).

J. McLachlan, C. Teng, D. Klapper, 1986, The Biochemical journal.

Environmental Analysis of Endocrine Disrupting Effects from Hydrocarbon Contaminants in the Ecosystem

J. McLachlan, 2000 .

Alterations of maternal estrogen levels during gestation affect the skeleton of female offspring.

K. Korach, J. McLachlan, R. Newbold, 1996, Endocrinology.

Developmental exposure to estrogens induces persistent changes in skeletal tissue.

K. Korach, J. McLachlan, R. Newbold, 1992, Endocrinology.

Detecting ligands and dissecting nuclear receptor-signaling pathways using recombinant strains of the yeast Saccharomyces cerevisiae

J. McLachlan, M. Burow, J. Fox, 2008, Nature Protocols.

Are estrogens carcinogenic during development of the testes?

J. McLachlan, M. Negishi, R. Newbold, 1998, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

Glyceollin, a novel regulator of mTOR/p70S6 in estrogen receptor positive breast cancer

J. McLachlan, E. Martin, L. Rhodes, 2015, The Journal of Steroid Biochemistry and Molecular Biology.

Developmental Toxicology: Mechanisms and Risks

C. Markert, J. McLachlan, R. Pratt, 1988 .

Estrogen-Dependent Gene Regulation by an Oxidative Metabolite of Diethylstilbestrol, Diethylstilbestrol-4′,4″-Quinone

K. Chae, K. Korach, J. McLachlan, 1998, Steroids.

Three orphan nuclear receptors in the scleractinian coral Pocillopora damicornis from the Pacific coast of Costa Rica

J. McLachlan, A. Tarrant, S. Atkinson, 2008 .

Accelerated onset of uterine tumors in transgenic mice with aberrant expression of the estrogen receptor after neonatal exposure to diethylstilbestrol

K. Korach, J. McLachlan, J. F. Couse, 1997, Molecular carcinogenesis.

Effects of estrogen on leptin gene promoter activation in MCF-7 breast cancer and JEG-3 choriocarcinoma cells: selective regulation via estrogen receptors α and β

J. McLachlan, M. Burow, M. C. Henson, 2001, Molecular and Cellular Endocrinology.

In Vitro and In Vivo evaluation of novel anticancer agents in triple negative Breast Cancer Models

J. McLachlan, L. Rhodes, M. Burow, 2013, Journal of health care for the poor and underserved.

In Vitro and In Vivo evaluation of n ovel a nticancer agents in t riple n egative Breast Cancer Models

J. McLachlan, L. Rhodes, M. Burow, 2013 .

Effects of 7-O substitutions on estrogenic and anti-estrogenic activities of daidzein analogues in MCF-7 breast cancer cells.

J. Sridhar, D. Bhatnagar, J. McLachlan, 2010, Journal of medicinal chemistry.

Growth of seminal vesicle epithelial cells in serum-free collagen gel culture

J. McLachlan, S. Harris, Y. Tomooka, 1985, In Vitro Cellular & Developmental Biology.

The effects of polychlorinated biphenyls given prenatally on the neurobehavioral development of mice.

H. Tilson, G. Lucier, J. McLachlan, 1979, Environmental research.

Phytochemical glyceollins, isolated from soy, mediate antihormonal effects through estrogen receptor alpha and beta.

T. Cleveland, J. McLachlan, B. Collins-Burow, 2001, The Journal of clinical endocrinology and metabolism.

The anti-estrogenic activity of selected polynuclear aromatic hydrocarbons in yeast expressing human estrogen receptor.

J. McLachlan, S. F. Arnold, D. Q. Tran, 1996, Biochemical and biophysical research communications.

Glyceollin I enantiomers distinctly regulate ER-mediated gene expression

D. Bhatnagar, T. Cleveland, J. McLachlan, 2010, Steroids.

Endocrine disrupting chemicals in New Orleans surface waters and Mississippi Sound sediments.

M. Lacey, J. McLachlan, S. E. O'reilly, 2012, Journal of environmental monitoring : JEM.

The inhibition of estrogen receptor-mediated responses by chloro-S-triazine-derived compounds is dependent on estradiol concentration in yeast.

J. McLachlan, S. F. Arnold, D. Q. Tran, 1996, Biochemical and biophysical research communications.

Evaluation of clinical and environmental anti-estrogens with human estrogen receptor expressed in Saccharomyces cerevisiae: a novel role for ABC-cassette transporters in mediating anti-estrogenic activity.

L. Jin, J. McLachlan, S. F. Arnold, 1997, Biochemical and Biophysical Research Communications - BBRC.

Synergistic effect of environmental estrogens: report withdrawn.

J. McLachlan, 1997, Science.