C. Spears

发表

Transfection of wild-type but not mutant p53 induces early monocytic differentiation in HL60 cells and increases their sensitivity to stress.

H. Lenz, D. Banerjee, J. Bertino, 1995, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Quantitation of intratumoral thymidylate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: preliminary report from an ongoing trial.

S. Groshen, H. Silberman, H. Lenz, 1995, European journal of cancer.

Intercellular communication mediates the bystander effect during herpes simplex thymidine kinase/ganciclovir-based gene therapy of human gastrointestinal tumor cells.

W. Anderson, H. Lenz, K. Danenberg, 1998, Human gene therapy.

Asymmetric Cell Division: Binomial Identities for Age Analysis of Mortal vs. Immortal Trees

C. Spears, M. Bicknell-Johnson, 1998 .

Active specific immunotherapy of metastatic melanoma with an antiidiotype vaccine: a phase I/II trial of I-Mel-2 plus SAF-m.

S. Groshen, C. Spears, J. Merritt, 1997, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

5,10-methylenetetrahydrofolic acid with 5-fluorouracil as first line treatment in metastatic colorectal cancer: Phase II study results.

C. Spears, T. Reid, S. Jelić, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phase I and pharmacologic study of i.v. hydroxyurea infusion given with i.p. 5-fluoro-2′-deoxyuridine and leucovorin

H. Silberman, C. Spears, F. Muggia, 2001, Anti-cancer drugs.

Intraperitoneal 5-fluoro-2′-deoxyuridine with escalating doses of leucovorin: Pharmacology and clinical tolerance

A. Tulpule, C. Spears, Kenneth K. Chan, 2004, Investigational New Drugs.

Prolonged continuous infusion of fluorouracil with weekly bolus leucovorin: a phase II study in patients with disseminated colorectal cancer.

S. Groshen, C. Spears, C. Leichman, 1993, Journal of the National Cancer Institute.

Restoration of wild-type p53 activity in p53-null HL-60 cells confers multidrug sensitivity.

Thomas D. Schmittgen, A. Schönthal, H. Lenz, 1998, Clinical cancer research : an official journal of the American Association for Cancer Research.

Normal Liver of Patients Given Intravenous 5-Fluorouracil Thymidylate Synthetase Inhibition in Malignant Tumors and Updated

L. Bernstein, C. Spears, P. Danenberg, 2006 .

Palladium-catalysed synthesis of some biologically active 5, 6-disubstituted uracils

C. Spears, S. Dasgupta, N. Kundu, 1996 .

5-(Acylethynyl)uracils, 5-(Acylethynyl)-2'-deoxyuridines and 5-(Acylethynyl)-1-(2-hydroxyethoxy)methyluracils. Their synthesis, antiviral and cytotoxic activities

C. Spears, J. Balzarini, E. Clercq, 1999 .

Unusual cytotoxicities of 5-(acylethynyl)-1-(2-hydroxyethoxy)methyluracils

C. Spears, N. Kundu, J. Mahanty, 1996 .

Synthesis and biological activities of [E]-5-(2-acylvinyl)uracils

C. Spears, S. Dasgupta, N. Kundu, 1993 .

Folinic acid modulation of fluorouracil: tissue kinetics of bolus administration

C. Spears, B. Gustavsson, R. Frösing, 1989, Investigational New Drugs.

Inhibition after 5-Fluorouracil Mechanisms of Innate Resistance to Thymidylate Synthase Updated

L. Bernstein, C. Spears, B. Gustavsson, 2006 .

Palladium-catalyzed synthesis of (E)-5-(2-acylvinyl)-2′-deoxyuridines and their antiviral and cytotoxic activities

C. Spears, J. Balzarini, E. Clercq, 1995 .

Preoperative systemic chemotherapy followed by adjuvant postoperative intraperitoneal therapy for gastric cancer: a University of Southern California pilot program.

L. Laine, H. Silberman, C. Spears, 1992, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Volume doubling measurement of spherical and ellipsoidal tumors.

C. Spears, 1984, Medical and pediatric oncology.

Altered gene expression of folate enzymes in adjacent mucosa is associated with outcome of colorectal cancer patients.

C. Spears, R. Willén, B. Gustavsson, 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

Patients Mucosa Is Associated with Outcome of Colorectal Cancer Altered Gene Expression of Folate Enzymes in Adjacent Updated Version

C. Spears, R. Willén, B. Gustavsson, 2003 .

Antitumor activity of combination 5,10-methylenetetrahydrofolate, 5-fluorouracil, and anti-vascular endothelial growth factor against human colorectal HT-29 tumors in nude mice.

C. Spears, J. Robbins, M. Cantwell, 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phase I-II study of weekly 5-fluorouracil and 5,10-methylene-tetrahydrofolate in patients with advanced gastrointestinal and breast cancer

C. Spears, B. Gustavsson, G. Carlsson, 1997 .