J. Ruppert

发表

Progression of basal cell carcinoma through loss of chromosome 9q and inactivation of a single p53 allele.

D. Sidransky, P. van der Riet, D. Karp, 1994, Cancer research.

A ROLE FOR P 63 IN THE REGULATION OF CELL CYCLE PROGRESSION AND CELL DEATH by

Xinbin Chen, D. Crawford, J. Ruppert, 2007 .

Bad things happen in the basal layer: KLF4 and squamous cell carcinoma

J. Ruppert, Wen Jiang, Susan M. Lobo-Ruppert, 2008, Cancer biology & therapy.

The zinc finger protein GLI transforms primary cells in cooperation with adenovirus E1A

B. Vogelstein, K. Kinzler, J. Ruppert, 1991 .

Scrambled exons

Kathleen R. Cho, K. Kinzler, B. Vogelstein, 1991, Cell.

Induction of KLF4 in basal keratinocytes blocks the proliferation–differentiation switch and initiates squamous epithelial dysplasia

T. Fitzgerald, A. Paterson, J. E. Kudlow, 2005, Oncogene.

Regulation of E2F1 by BRCT Domain-Containing Protein TopBP1

J. Ruppert, Kang Z. Liu, F. Lin, 2003, Molecular and Cellular Biology.

Evidence for two bladder cancer suppressor loci on human chromosome 9.

D. Sidransky, K. Tokino, J. Ruppert, 1993, Cancer research.

Alternatively spliced hBRF variants function at different RNA polymerase III promoters

J. Ruppert, S. Lobo-ruppert, V. McCulloch, 2000, The EMBO journal.

Hedgehog signaling and response to cyclopamine differs in epithelial and stromal cells in benign breast and breast cancer

G. Page, Martin R. Johnson, J. Ruppert, 2006, Cancer biology & therapy.

Analysis of a protein-binding domain of p53

B. Stillman, J. Ruppert, 1993, Molecular and cellular biology.

Identification of a chromosome 18q gene that is altered in colorectal cancers.

Kathleen R. Cho, K. Kinzler, B. Vogelstein, 1990, Science.

Suppression subtractive hybridization for identification and functional analysis of tumor suppressor genes.

J. Ruppert, I. Louro, E. Bailey, 2003, Methods in molecular biology.

Epithelial transformation by KLF4 requires Notch1 but not canonical Notch1 signaling

L. Teng, K. Bland, J. Ruppert, 2009, Cancer biology & therapy.

Kruppel-like Pluripotency Factors as Modulators of Cancer Cell Therapeutic Responses.

J. Ruppert, M. Farrugia, M. Salkeni, 2016, Cancer research.

Structural alterations of the epidermal growth factor receptor gene in human gliomas.

P. Humphrey, B. Vogelstein, S. Bigner, 1992, Proceedings of the National Academy of Sciences of the United States of America.

The Zinc Finger Protein GLI Transforms Primary Cells in Cooperation with Adenovirus ElA

B. Vogelstein, J. Ruppert, W. Kenneth, 2004 .

Gli1 acts through Snail and E-cadherin to promote nuclear signaling by beta-catenin.

J. Ruppert, S. Lobo-ruppert, X. Li, 2007, Oncogene.

Snail induction is an early response to Gli1 that determines the efficiency of epithelial transformation

M. Kraus, J. Ruppert, X. Li, 2006, Oncogene.

Gene therapy strategies for carcinoma of the breast

D. Curiel, J. Ruppert, G. Bilbao, 1997, Breast Cancer Research and Treatment.

The zinc finger protein GLI transforms primary cells in cooperation with adenovirus E1A

K. Kinzler, B. Vogelstein, J. Ruppert, 1991, Molecular and cellular biology.

GLI3 encodes a 190-kilodalton protein with multiple regions of GLI similarity

K. Kinzler, B. Vogelstein, J. Ruppert, 1990, Molecular and cellular biology.

The GLI-Kruppel family of human genes

S. O’Brien, K. Kinzler, B. Vogelstein, 1988, Molecular and cellular biology.

The GLI gene is a member of the Kruppel family of zinc finger proteins

Bert Vogelstein, Kenneth W. Kinzler, K. Kinzler, 1988, Nature.

Inhibition of DNA replication factor RPA by p53

E. Winchester, J. Aster, Anindya Dutta, 1993, Nature.

MicroRNA‐Based Therapeutic Strategies for Targeting Mutant and Wild Type RAS in Cancer

J. Ruppert, Sriganesh B Sharma, 2015, Drug development research.

metabolismsex-dependent and -independent liver Regulator of sex-limitation KRAB zinc finger proteins

James H. Fugett, C. Creighton, L. Yin, 2015 .

Regulation of anti-apoptotic signaling by Kruppel-like factors 4 and 5 mediates lapatinib resistance in breast cancer

P. Stoilov, C. Creighton, J. Ruppert, 2015, Cell Death and Disease.

Head and Neck Cancer Mutations Increases with Progression of p 53 The Incidence of Updated Version

D. Sidransky, Y. Eby, J. Ruppert, 2007 .

Advances in Brief The Incidence of p 53 Mutations Increases with Progression of Head and Neck Cancer

R. Hruban, D. Sidransky, Y. Eby, 2007 .

A KLF4–miRNA-206 Autoregulatory Feedback Loop Can Promote or Inhibit Protein Translation Depending upon Cell Context

Chen-Chung Lin, Alexey V. Ivanov, William F. Wonderlin, 2011, Molecular and Cellular Biology.

MicroRNAs 206 and 21 Cooperate To Promote RAS–Extracellular Signal-Regulated Kinase Signaling by Suppressing the Translation of RASA1 and SPRED1

J. Ruppert, Chen-Chung Lin, E. Ellis, 2014, Molecular and Cellular Biology.

Prevention of KLF4-mediated tumor initiation and malignant transformation by UAB30 rexinoid

J. Ruppert, Wen Jiang, C. Grubbs, 2009, Cancer biology & therapy.

Comparative gene expression profile analysis of GLI and c-MYC in an epithelial model of malignant transformation.

Aubrey E. Hill, Martin R. Johnson, J. Ruppert, 2002, Cancer research.

Oncogene expression cloning by retroviral transduction of adenovirus E1A-immortalized rat kidney RK3E cells: transformation of a host with epithelial features by c-MYC and the zinc finger protein GKLF.

J. Ruppert, W. Grizzle, L. Chow, 1999, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Identification the Prostate of Novel Oncogenes in Carcinoma of 6

J. Ruppert, 2022 .

Inhibition of tumorigenicity by the 5'-untranslated RNA of the human c-myc P0 transcript.

J. Ruppert, W. Grizzle, P. Emanuel, 2003, Experimental cell research.

Induction of endogenous telomerase (hTERT) by c-Myc in WI-38 fibroblasts transformed with specific genetic elements.

J. Ruppert, T. Tollefsbol, L. G. Andrews, 2003, Gene.

Gene amplification of c-myc and N-myc in small cell carcinoma of the lung.

S. Baylin, B. Vogelstein, J. Ruppert, 1986, Science.

The incidence of p53 mutations increases with progression of head and neck cancer.

R. Hruban, D. Sidransky, Y. Eby, 1993, Cancer research.

KLF4 and PCNA identify stages of tumor initiation in a conditional model of cutaneous squamous epithelial neoplasia

J. Ruppert, A. Frost, Conway C. Huang, 2005, Cancer biology & therapy.

REGULATION OF β-CATENIN BY GLI1 IN EPITHELIAL TRANSFORMATION

P. Detloff, J. Ruppert, J. Engler, 2006 .

Functional Hierarchy and Cooperation of EMT Master Transcription Factors in Breast Cancer Metastasis

James H. Fugett, C. Creighton, A. Ivanov, 2021, Molecular Cancer Research.

The p44S10 locus, encoding a subunit of the proteasome regulatory particle, is amplified during progression of cutaneous malignant melanoma

William E Grizzle, Jeffrey M Trent, David I. Smith, 2000, Oncogene.

Allelotype of head and neck squamous cell carcinoma.

R. Hruban, D. Sidransky, W. Koch, 1994, Cancer research.

KAP1 promotes proliferation and metastatic progression of breast cancer cells.

James H. Fugett, C. Creighton, A. Ivanov, 2015, Cancer research.

KAP 1 Promotes Proliferation and Metastatic Progression of Breast Cancer Cells

James H. Fugett, C. Creighton, A. Ivanov, 2014 .

Kruppel-like factor 4 signals through microRNA-206 to promote tumor initiation and cell survival

J. Ruppert, R. Ice, S. Sharma, 2015, Oncogenesis.

Conditional knockout of SHP2 in ErbB2 transgenic mice or inhibition in HER2-amplified breast cancer cell lines blocks oncogene expression and tumorigenesis

A. Ivanov, J. Ruppert, Y. Agazie, 2018, Oncogene.

Microsatellite instability in bladder cancer.

D. Sidransky, K. Tokino, J. Ruppert, 1993, Cancer research.

Nuclear Localization of KLF4 Is Associated with an Aggressive Phenotype in Early-Stage Breast Cancer

K. Bland, T. Fitzgerald, J. Ruppert, 2004, Clinical Cancer Research.

SOX9 inhibits &bgr;-TrCP-mediated protein degradation to promote nuclear GLI1 expression and cancer stem cell properties

J. Ruppert, K. Martin, Chen-Chung Lin, 2015, Journal of Cell Science.

PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism

M. Lawton, R. Shenkar, I. Awad, 2021, Nature.

The zinc finger protein GLI induces cellular sensitivity to the mTOR inhibitor rapamycin.

J. Ruppert, H. Gosnell, I. Louro, 1999, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Gli1 acts through Snail and E-cadherin to promote nuclear signaling by β-catenin

J. Ruppert, X. Li, S. Lobo-ruppert, 2007, Oncogene.

Increase of GKLF messenger RNA and protein expression during progression of breast cancer.

J. Ruppert, W. Grizzle, J. Engler, 2000, Cancer research.

Sox9 Inhibits -Trcp-Mediated Protein Degradation To Promote Nuclear Gli1 Expression And Cancer Stem Cell Properties

J. Ruppert, K. Martin, Chen-Chung Lin, 2018 .

Lack of Efficacy of the Statins Atorvastatin and Lovastatin in Rodent Mammary Carcinogenesis

V. Steele, J. Ruppert, R. Lubet, 2009, Cancer Prevention Research.

Advances in Brief Microsatellite instability in Bladder Cancer I

Peter A. Jones, D. Sidransky, K. Tokino, 2007 .

Keratinocyte-Targeted Expression of Human Laminin γ2 Rescues Skin Blistering and Early Lethality of Laminin γ2 Deficient Mice

J. Uitto, J. Ruppert, D. Keene, 2012, PloS one.

Disseminated calcitonin-poor medullary thyroid carcinoma in a patient with calcitonin-rich primary tumor.

J. Ruppert, J. Eggleston, S. Baylin, 1986, The American journal of surgical pathology.

Growth Hormone-induced Alteration in ErbB-2 Phosphorylation Status in 3T3-F442A Fibroblasts*

J. Houtman, J. Ruppert, J. Ruppert, 1999, The Journal of Biological Chemistry.