J. Selfridge

发表

Mice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning

J. Mcwhir, D. Harrison, J. Selfridge, 1993, Nature Genetics.

Reversal of Neurological Defects in a Mouse Model of Rett Syndrome

A. Bird, S. Cobb, J. Selfridge, 2007, Science.

CpG islands influence chromatin structure via the CpG-binding protein Cfp1

Robert S. Illingworth, A. Bird, D. Turner, 2010, Nature.

Mice with adenine phosphoribosyltransferase deficiency develop fatal 2,8-dihydroxyadenine lithiasis.

J. Selfridge, D. Melton, N. Redhead, 1996, Human gene therapy.

Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability

A. Bird, J. Jiricny, J. Selfridge, 2011, Nature.

Toxicity of overexpressed MeCP 2 is independent of HDAC 3 activity

A. Bird, M. Lazar, J. Selfridge, 2018 .

Toxicity of overexpressed MeCP2 is independent of HDAC3 activity

A. Bird, M. Lazar, J. Selfridge, 2018, Genes & development.

Base Excision by Thymine DNA Glycosylase Mediates DNA-Directed Cytotoxicity of 5-Fluorouracil

J. Selfridge, T. Lettieri, C. Kunz, 2009, PLoS Biology.

Comparative analysis of potential broad-spectrum neuronal Cre drivers

A. Bird, J. Selfridge, Jacky Guy, 2022, Wellcome open research.

Gene targeting using a mouse HPRT minigene/HPRT-deficient embryonic stem cell system: Inactivation of the mouseERCC-1 gene

J. Mcwhir, J. Selfridge, D. Melton, 1992, Somatic cell and molecular genetics.

Double Replacement Gene Targeting for the Production of a Series of Mouse Strains with Different Prion Protein Gene Alterations

Richard C. Moore, J. Selfridge, D. Melton, 1995, Bio/Technology.

SALL4 controls cell fate in response to DNA base composition

A. Bird, M. Vermeulen, Konstantina Skourti-Stathaki, 2020, bioRxiv.

Mice with DNA repair gene Ercc1 deficiency in a neural crest lineage are a model for late-onset Hirschsprung disease.

Liang Song, J. Selfridge, D. Melton, 2010, DNA repair.

Affinity for DNA Contributes to NLS Independent Nuclear Localization of MeCP2

A. Bird, J. Selfridge, Cara Merusi, 2018, Cell reports.

Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes

A. Bird, S. Cobb, C. Loughrey, 2016, Human molecular genetics.

Morphological and functional reversal of phenotypes in a mouse model of Rett syndrome.

A. Bird, S. Cobb, G. Riedel, 2012, Brain : a journal of neurology.

Mice with gene targetted prion protein alterations show that Prnp, Sine and Prni are congruent

Richard C. Moore, I. Mcconnell, J. Selfridge, 1998, Nature Genetics.

Male infertility and DNA damage in Doppel knockout and prion protein/Doppel double-knockout mice.

J. Selfridge, D. Melton, P. Saunders, 2004, The American journal of pathology.

1 Radically truncated MeCP 2 rescues Rett syndrome-like neurological defects 1

A. Bird, S. Cobb, J. Selfridge, 2017 .

Mice with skin-specific DNA repair gene (Ercc1) inactivation are hypersensitive to ultraviolet irradiation-induced skin cancer and show more rapid actinic progression

J. Selfridge, D. Melton, J. Doig, 2006, Oncogene.

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

A. Bird, M. Greenberg, J. Rappsilber, 2013, Nature Neuroscience.

The role of MeCP2 in the brain.

Jim Selfridge, Adrian Bird, A. Bird, 2009, Annual review of cell and developmental biology.

Kaiso-Deficient Mice Show Resistance to Intestinal Cancer

A. Bird, J. Mariadason, L. Augenlicht, 2006, Molecular and Cellular Biology.

An Orphan CpG Island Drives Expression of a let-7 miRNA Precursor with an Important Role in Mouse Development

A. Bird, C. Lelliott, R. Ramirez-Solis, 2019, Epigenomes.

A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog

H. Lassmann, J. Selfridge, J. Zezula, 2014, Development.

Neuronal non-CG methylation is an essential target for MeCP2 function

A. Bird, S. Kriaucionis, J. Selfridge, 2020, bioRxiv.

A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells

A. Bird, A. Ivens, R. Maizels, 2015, Nature Communications.

A position- and orientation-dependent element in the first intron is required for expression of the mouse hprt gene in embryonic stem cells.

J. Selfridge, D. Melton, T. Magin, 1992, Gene.

Deletion of Genes Implicated in Protecting the Integrity of Male Germ Cells Has Differential Effects on the Incidence of DNA Breaks and Germ Cell Loss

J. Selfridge, D. Melton, P. Saunders, 2007, PloS one.

DNA repair gene Ercc1 is essential for normal spermatogenesis and oogenesis and for functional integrity of germ cell DNA in the mouse

J. Selfridge, D. Melton, K. Hsia, 2003, Development.

A mutation-led search for novel functional domains in MeCP2

A. Bird, J. Selfridge, Martha V. Koerner, 2018, bioRxiv.

53BP1 exchanges slowly at the sites of DNA damage and appears to require RNA for its association with chromatin

J. Selfridge, D. Melton, Y. Adachi, 2005, Journal of Cell Science.

Correction of liver dysfunction in DNA repair-deficient mice with an ERCC1 transgene.

J. Selfridge, D. Melton, K. Hsia, 2001, Nucleic acids research.

MeCP2 recognizes cytosine methylated tri-nucleotide and di-nucleotide sequences to tune transcription in the mammalian brain

A. Bird, G. Schweikert, G. Sanguinetti, 2017, PLoS genetics.

Domains of methylated CAC and CG target MeCP2 to tune transcription in the brain

A. Bird, G. Schweikert, G. Sanguinetti, 2016, bioRxiv.

The molecular basis of variable phenotypic severity among common missense mutations causing Rett syndrome

A. Bird, J. Selfridge, Cara Merusi, 2015, Human molecular genetics.

DNA ligase I is required for fetal liver erythropoiesis but is not essential for mammalian cell viability

K. Samuel, J. Selfridge, D. Melton, 1996, Nature Genetics.

Enhanced CpG Mutability and Tumorigenesis in MBD4-Deficient Mice

A. Bird, P. Keightley, O. Sansom, 2002, Science.

Radically truncated MeCP2 rescues Rett syndrome-like neurological defects

A. Bird, S. Cobb, J. Selfridge, 2017, Nature.

Postnatal inactivation reveals enhanced requirement for MeCP2 at distinct age windows.

A. Bird, J. Selfridge, Cara Merusi, 2012, Human molecular genetics.

Up-regulation of glucocorticoid-regulated genes in a mouse model of Rett syndrome.

A. Bird, H. Ropers, Tim C. Roloff, 2005, Human molecular genetics.

Stability of HPRT marker gene expression at different gene-targeted loci: observing and overcoming a position effect.

J. Selfridge, D. Melton, A. Ketchen, 1997, Nucleic acids research.

Reduced seizure threshold and altered network oscillatory properties in a mouse model of Rett syndrome

Alex D. Bird, S. Cobb, J. Selfridge, 2013, Neuroscience.

A novel transcript for DNA repair gene Ercc1 in mouse skin

J. Selfridge, D. Melton, A. G. Winter, 2011, Transgenic Research.

A One-Step Gene Amplification System for Use in Cultured Mammalian Cells and Transgenic Animals

A. Kind, J. Selfridge, D. Melton, 2001, Transgenic research.

CpG islands influence chromatin structure via the CpG-binding protein Cfp1

Robert S. Illingworth, A. Bird, D. Turner, 2010, Nature.

The role of MeCP2 in the brain.

A. Bird, J. Selfridge, Jacky Guy, 2011, Annual review of cell and developmental biology.