D. Ginsberg

发表

Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding

E. Shaulian, M. Oren, A. Zauberman, 1992 .

p53-dependent Down-regulation of Telomerase Is Mediated by p21waf1*

V. Rotter, R. Brosh, I. Kogan, 2004, Journal of Biological Chemistry.

Wild-type p53 can down-modulate the activity of various promoters.

M. Yaniv, M. Oren, D. Ginsberg, 1991, Proceedings of the National Academy of Sciences of the United States of America.

E2F1 regulates autophagy and the transcription of autophagy genes

D. Ginsberg, S. Polager, M. Ofir, 2008, Oncogene.

E2F1 Modulates p38 MAPK Phosphorylation via Transcriptional Regulation of ASK1 and Wip1*

D. Ginsberg, S. Polager, T. Hershko, 2006, Journal of Biological Chemistry.

Transcriptional regulation of AKT activation by E2F.

D. Ginsberg, M. Chaussepied, Marie Chaussepied, 2004, Molecular cell.

E2Fs up-regulate expression of genes involved in DNA replication, DNA repair and mitosis

Y. Kalma, D. Ginsberg, S. Polager, 2002, Oncogene.

E2F1 pathways to apoptosis

D. Ginsberg, 2002, FEBS letters.

Regulation of the retinoblastoma protein-related protein p107 by G1 cyclin-associated kinases.

M. Ewen, D. Livingston, Z. Xiao, 1996, Proceedings of the National Academy of Sciences of the United States of America.

ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype

I. Harman-boehm, M. Blüher, D. Ginsberg, 2017, Molecular metabolism.

The subcellular localization of E2F-4 is cell-cycle dependent.

D. Livingston, D. Ginsberg, S. Gaubatz, 1997, Proceedings of the National Academy of Sciences of the United States of America.

p53 and E2f: partners in life and death

D. Ginsberg, S. Polager, Doron Ginsberg, 2009, Nature Reviews Cancer.

LncRNA Khps1 Regulates Expression of the Proto-oncogene SPHK1 via Triplex-Mediated Changes in Chromatin Structure.

I. Grummt, D. Ginsberg, Anna Postepska-Igielska, 2015, Molecular cell.

A novel lncRNA, GASL1, inhibits cell proliferation and restricts E2F1 activity

Katerina Shamalov, Cyrille J. Cohen, D. Ginsberg, 2017, Oncotarget.

Cell Death , and Senescence miR-15 and miR-16 Are Direct Transcriptional Targets of E 2 F 1 that Limit E 2 F-Induced Proliferation by Targeting Cyclin E

D. Ginsberg, M. Ofir, Doron Ginsberg, 2011 .

JNK activation is regulated by E2F and promotes E2F1-induced apoptosis.

D. Ginsberg, Dalia Hacohen, Dana Bashari, 2011, Cellular signalling.

The Tumor Suppressor Maspin Mediates E2F1-Induced Sensitivity of Cancer Cells to Chemotherapy

D. Ginsberg, Dalia Hacohen, Berta Ben Shachar, 2010, Molecular Cancer Research.

ATM is a target for positive regulation by E2F-1

D. Ginsberg, E. Berkovich, Eli Berkovich, 2003, Oncogene.

Ras Induces Elevation of E2F-1 mRNA Levels*

D. Ginsberg, E. Berkovich, Eli Berkovich, 2001, The Journal of Biological Chemistry.

Regulation of modular Cyclin and CDK feedback loops by an E2F transcription oscillator in the mammalian cell cycle.

Orit Lavi, Y. Louzoun, D. Ginsberg, 2011, Mathematical biosciences and engineering : MBE.

Reduced abundance of the E3 ubiquitin ligase E6AP contributes to decreased expression of the INK4/ARF locus in non–small cell lung cancer

S. Fox, B. Solomon, P. Russell, 2017, Science Signaling.

Functional interaction between E2F-4 and p130: evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members.

D. Livingston, D. Ginsberg, G. Vairo, 1995, Genes & development.

Protein-binding elements in the promoter region of the mouse p53 gene.

J. Piette, M. Yaniv, M. Oren, 1990, Oncogene.

Induction of chondrocyte growth arrest by FGF: transcriptional and cytoskeletal alterations.

O. Rozenblatt-Rosen, D. Ginsberg, E. Sadot, 2002, Journal of cell science.

EGFR Signaling Inhibits E2F1-Induced Apoptosis in Vivo: Implications for Cancer Therapy

D. Ginsberg, 2007, Science's STKE.

p 53-dependent Down-regulation of Telomerase Is Mediated by p 21 waf 1 *

V. Rotter, R. Brosh, I. Kogan, 2004 .

Identification ofaMinimal Transforming Domainofp53: Negative Dominance through Abrogation of Sequence-Specific

D. Ginsberg, A. Oren, 1992 .

ERK activation is regulated by E2F1 and is essential for E2F1-induced S phase entry.

D. Ginsberg, K. Korotayev, M. Chaussepied, 2008, Cellular signalling.

E2F3-a novel repressor of the ARF/p53 pathway.

D. Ginsberg, 2004, Developmental cell.

Expression of a novel cadherin (EP-cadherin) in unfertilized eggs and early Xenopus embryos.

B. Geiger, D. Ginsberg, D. DeSimone, 1991, Development.

Induction of growth arrest by a temperature-sensitive p53 mutant is correlated with increased nuclear localization and decreased stability of the protein

M. Oren, D. Ginsberg, D. Michael-Michalovitz, 1991, Molecular and cellular biology.

Prolonged culture of telomerase-immortalized human fibroblasts leads to a premalignant phenotype.

V. Rotter, Y. Tabach, N. Goldfinger, 2003, Cancer research.

The mitotic checkpoint gene, SIL is regulated by E2F1

S. Izraeli, D. Ginsberg, M. Chaussepied, 2008, International journal of cancer.

A conserved region of unknown function participates in the recognition of E2F family members by the adenovirus E4 ORF 6/7 protein.

W. Kaelin, C. A. Jost, D. Ginsberg, 1996, Virology.

Cancer cells survival is dependent on the lincRNA JUNI

Prof Vikas Kumar, E. Shaulian, Alena Shkumatava, 2022, bioRxiv.

The long non-coding RNA ERIC is regulated by E2F and modulates the cellular response to DNA damage

T. Doniger, G. Rechavi, D. Ginsberg, 2013, Molecular Cancer.

Transcriptional programs following genetic alterations in p53, INK4A, and H-Ras genes along defined stages of malignant transformation.

V. Rotter, Y. Tabach, Y. Buganim, 2005, Cancer research.

Genetic Alterations in p 53 , INK 4 A , and HRas Genes along Defined Stages of Malignant Transformation

V. Rotter, Y. Tabach, Y. Buganim, 2005 .

Targeting LINC00673 expression triggers cellular senescence in lung cancer

Frédérick A. Mallette, A. Warth, P. Schnabel, 2018, RNA biology.

Binding and modulation of p53 by p300/CBP coactivators

D. Livingston, J. Decaprio, S. Grossman, 1997, Nature.

In Vitro Evaluation of Chemically Analyzed Hypericum Triquetrifolium Extract Efficacy in Apoptosis Induction and Cell Cycle Arrest of the HCT-116 Colon Cancer Cell Line

D. Ginsberg, Zipora Tietel, B. Saad, 2019, Molecules.

Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding

E. Shaulian, M. Oren, A. Zauberman, 1992, Molecular and cellular biology.

E2F Mediates Sustained G2 Arrest and Down-regulation of Stathmin and AIM-1 Expression in Response to Genotoxic Stress*

D. Ginsberg, S. Polager, Shirley Polager, 2003, The Journal of Biological Chemistry.

The long non-coding RNA ERIC is regulated by E2F and modulates the cellular response to DNA damage

T. Doniger, G. Rechavi, D. Ginsberg, 2013, Molecular Cancer.

miR-15 and miR-16 Are Direct Transcriptional Targets of E2F1 that Limit E2F-Induced Proliferation by Targeting Cyclin E

D. Ginsberg, M. Ofir, Doron Ginsberg, 2011, Molecular Cancer Research.

E2F - at the crossroads of life and death.

D. Ginsberg, S. Polager, Shirley Polager, 2008, Trends in cell biology.

A novel mitosis-associated lncRNA, MA-linc1, is required for cell cycle progression and sensitizes cancer cells to Paclitaxel

S. Efroni, D. Ginsberg, Moriah Gidoni, 2015, Oncotarget.

LncRNA Khps 1 Regulates Expression of the Proto-oncogene SPHK 1 via Triplex-Mediated Changes in Chromatin Structure Graphical

I. Grummt, D. Ginsberg, Anna Postepska-Igielska, 2022 .

Expression analysis using DNA microarrays demonstrates that E2F-1 up-regulates expression of DNA replication genes including replication protein A2

Y. Kalma, D. Ginsberg, L. Marash, 2001, Oncogene.

E 2 F – at the crossroads of life and death

D. Ginsberg, S. Polager, Shirley Polager, 2008 .

Up-regulation of Bcl-2 Homology 3 (BH3)-only Proteins by E2F1 Mediates Apoptosis*

D. Ginsberg, T. Hershko, 2004, Journal of Biological Chemistry.

E2F and Ras Synergize in Transcriptionally Activating p14ARF Expression

D. Ginsberg, Eli Berkovich, Yocheved Lamed, 2003, Cell cycle.

RBM38 Is a Direct Transcriptional Target of E2F1 that Limits E2F1-Induced Proliferation

S. Efroni, D. Ginsberg, Rotem Ben-Hamo, 2012, Molecular Cancer Research.

Cell Cycle , Cell Death , and Senescence RBM 38 Is a Direct Transcriptional Target of E 2 F 1 that Limits E 2 F 1-Induced Proliferation

S. Efroni, D. Ginsberg, Rotem Ben-Hamo, 2012 .

p53-repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation

Shalom Madar, Ido Goldstein, Varda Rotter, 2008, Molecular systems biology.

The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells

S. Kalkanis, L. Poisson, D. Ginsberg, 2017, Oncotarget.

E2F and Signal Transduction Pathways

D. Ginsberg, M. Chaussepied, 2005, Cell cycle.

E2F-4, a new member of the E2F transcription factor family, interacts with p107.

J. Lawrence, D. Livingston, J. Decaprio, 1994, Genes & development.

Nuclear membrane protein LAP2beta mediates transcriptional repression alone and together with its binding partner GCL (germ-cell-less).

N. Copeland, D. Gilbert, N. Jenkins, 2001, Journal of cell science.

Modulation of the E2F1-driven cancer cell fate by the DNA damage response machinery and potential novel E2F1 targets in osteosarcomas.

J. Bartek, G. Velimezi, T. Halazonetis, 2009, The American journal of pathology.

Novel link between E2F and p53: proapoptotic cofactors of p53 are transcriptionally upregulated by E2F

M. Oren, D. Ginsberg, T. Hershko, 2005, Cell Death and Differentiation.

Codanin-1, the protein encoded by the gene mutated in congenital dyserythropoietic anemia type I (CDAN1), is cell cycle-regulated

H. Tamary, G. Kupfer, D. Ginsberg, 2009, Haematologica.

TODRA, a lncRNA at the RAD51 Locus, Is Oppositely Regulated to RAD51, and Enhances RAD51-Dependent DSB (Double Strand Break) Repair

D. Zeevi, A. Lahad, D. Ginsberg, 2015, PloS one.

Elevated autophagy gene expression in adipose tissue of obese humans: A potential non-cell-cycle-dependent function of E2F1

I. Harman-boehm, M. Blüher, D. Ginsberg, 2015, Autophagy.

Transcription factor E2F1 is a potent transactivator of the insulin-like growth factor-I receptor (IGF-IR) gene.

Metsada Pasmanik-Chor, H. Schayek, S. Plymate, 2010, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Theileria parasites subvert E2F signaling to stimulate leukocyte proliferation

Joana C. Silva, A. Pain, V. Nene, 2020, Scientific Reports.

Induction ofGrowthArrest bya Temperature-Sensitive p53Mutant IsCorrelated withIncreased Nuclear Localization andDecreased Stability oftheProtein

M. Oren, D. Ginsberg, D. Michael-Michalovitz, 1991 .

A possible involvement of virus-associated protease in the fusion of Sendai virus envelopes with human erythrocytes.

D. Ginsberg, A. Loyter, N. Zakai, 1983, Biochimica et biophysica acta.

Correction: The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells

L. Poisson, D. Ginsberg, Wei Jiang, 2021, OncoTarget.

Transfected mouse c-jun can inhibit transformation of primary rat embryo fibroblasts.

M. Yaniv, M. Oren, D. Ginsberg, 1991, Oncogene.