T. Tan

发表

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life

A. Levine, M. Oren, P. Hinds, 1988, Molecular and cellular biology.

Identification of the p53 protein domain involved in formation of the simian virus 40 large T-antigen-p53 protein complex

A. Levine, T. Tan, J. Wallis, 1986, Journal of virology.

TBK1-associated Protein in Endolysosomes (TAPE)/CC2D1A Is a Key Regulator Linking RIG-I-like Receptors to Antiviral Immunity*

P. Ling, T. Tan, H. Lei, 2012, The Journal of Biological Chemistry.

Involvement of Hematopoietic Progenitor Kinase 1 in T Cell Receptor Signaling*

M. C. Hu, P. Ling, M. Hu, 2001, The Journal of Biological Chemistry.

Oncogene activation of HIV-LTR-driven expression via the NF-ϰB binding sites

T. Tan, U. Rapp, G. Heidecker, 1993 .

Cellular transcription factors and regulation of IL-2 receptor gene expression by HTLV-I tax gene product.

R. Roeder, S. Ruben, W. Haseltine, 1988, Science.

Regulation of PKC-θ function by phosphorylation in T cell receptor signaling

T. Tan, Xiaohong Wang, Ju-Pi Li, 2012, Front. Immun..

Induction of DUSP14 ubiquitination by PRMT5-mediated arginine methylation

T. Tan, H. Chuang, Chia-Yu Yang, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Inhibition of JNK2 Disrupts Anaphase and Produces Aneuploidy in Mammalian Cells*

T. Tan, R. A. MacCorkle, 2004, Journal of Biological Chemistry.

Persistent Activation of c-Jun N-terminal Kinase 1 (JNK1) in γ Radiation-induced Apoptosis (*)

T. Tan, C. Meyer, Yi-rong Chen, 1996, The Journal of Biological Chemistry.

Tumorigenesis Suppressor Pdcd4 Down-Regulates Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 Expression To Suppress Colon Carcinoma Cell Invasion

N. Colburn, T. Tan, Qing Wang, 2006, Molecular and Cellular Biology.

Leukocyte-specific adaptor protein Grap2 interacts with hematopoietic progenitor kinase 1 (HPK1) to activate JNK signaling pathway in T lymphocytes

P. Ling, Mingyao Liu, T. Tan, 2001, Oncogene.

Hematopoietic progenitor kinase-1 (HPK1) stress response signaling pathway activates IκB kinases (IKK-α/β) and IKK-β is a developmentally regulated protein kinase

M. C. Hu, A. Mikhail, M. Hu, 1999, Oncogene.

Interaction of Hematopoietic Progenitor Kinase 1 and c-Abl Tyrosine Kinase in Response to Genotoxic Stress*

R. Weichselbaum, P. Ling, P. Sathyanarayana, 2001, The Journal of Biological Chemistry.

Butylated hydroxyanisole and its metabolite tert-butylhydroquinone differentially regulate mitogen-activated protein kinases. The role of oxidative stress in the activation of mitogen-activated protein kinases by phenolic antioxidants.

R. Yu, A. Kong, T. Tan, 1997, The Journal of biological chemistry.

MAP4K Family Kinases in Immunity and Inflammation.

T. Tan, Xiaohong Wang, H. Chuang, 2016, Advances in immunology.

MAP4K Family Kinases and DUSP Family Phosphatases in T-Cell Signaling and Systemic Lupus Erythematosus

T. Tan, H. Chuang, 2019, Cells.

Interaction between c-Rel and the Mitogen-activated Protein Kinase Kinase Kinase 1 Signaling Cascade in Mediating B Enhancer Activation (*)

T. Tan, X. Wang, D. Templeton, 1996, The Journal of Biological Chemistry.

The c-rel protooncogene product c-Rel but not NF-kappa B binds to the intronic region of the human interferon-gamma gene at a site related to an interferon-stimulable response element.

A. Sica, M. Kretzschmar, H. Young, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Activation of caspase-3 and c-Jun NH2-terminal kinase-1 signaling pathways in tamoxifen-induced apoptosis of human breast cancer cells.

R. Yu, S. Mandlekar, A. Kong, 2000, Cancer research.

RBM4-SRSF3-MAP4K4 splicing cascade modulates the metastatic signature of colorectal cancer cell.

Yu-Chih Liang, T. Tan, Jung-Chun Lin, 2018, Biochimica et biophysica acta. Molecular cell research.

Dual-specificity phosphatase 6 deficiency regulates gut microbiome and transcriptome response against diet-induced obesity in mice

Yu-Chieh Liao, T. Tan, H. Chan, 2016, Nature Microbiology.

Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin

T. Tan, Yi-rong Chen, Yi-Rong Chen, 1998, Oncogene.

The CUL7/F-box and WD Repeat Domain Containing 8 (CUL7/Fbxw8) Ubiquitin Ligase Promotes Degradation of Hematopoietic Progenitor Kinase 1*

Huamin Wang, Hua Wang, J. Abbruzzese, 2013, The Journal of Biological Chemistry.

Genomic sequencing and functional analyses identify MAP4K3/GLK germline and somatic variants associated with systemic lupus erythematosus

T. Tan, W. Hung, Yi-Ming Chen, 2021, Annals of the Rheumatic Diseases.

Molecular Mechanisms of c-Jun N-terminal Kinase-mediated Apoptosis Induced by Anticarcinogenic Isothiocyanates*

A. Kong, T. Tan, Wenfu Wang, 1998, The Journal of Biological Chemistry.

Mitogen-activated protein kinases in cell-cycle control

T. Tan, R. A. MacCorkle, Rebecca A. MacCorkle, 2007, Cell Biochemistry and Biophysics.

DUSP3 regulates phosphorylation-mediated degradation of occludin and is required for maintaining epithelial tight junction

T. Tan, Hsiao-Chin Chou, Chi-Hwa Yang, 2022, Journal of biomedical science.

p38 Mitogen-activated Protein Kinase Negatively Regulates the Induction of Phase II Drug-metabolizing Enzymes That Detoxify Carcinogens*

R. Yu, S. Mandlekar, A. Kong, 2000, The Journal of Biological Chemistry.

MAPKKK6, a novel mitogen-activated protein kinase kinase kinase, that associates with MAPKKK5.

T. Tan, X. Wang, K. Diener, 1998, Biochemical and biophysical research communications.

Proteomic analysis of resting and thrombin‐stimulated platelets reveals the translocation and functional relevance of HIP‐55 in platelets

T. Tan, Hongbo Hu, K. Tucker, 2009, Proteomics.

Phenethyl isothiocyanate, a natural chemopreventive agent, activates c-Jun N-terminal kinase 1.

R. Yu, A. Kong, T. Tan, 1996, Cancer research.

Dusp6 Depletion Enhances Gut Barrier Integrity and Microbiota Eubiosis Against Dextran Sulfate Sodium-Induced Colitis in Mice

H. Juan, Yu-Chieh Liao, T. Tan, 2020 .

MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo

Michael D. Schneider, M. Entman, M. Xie, 2020, Cell stem cell.

BPI overexpression suppresses Treg differentiation and induces exosome-mediated inflammation in systemic lupus erythematosus

T. Tan, Yi-Ming Chen, H. Chuang, 2021, Theranostics.

The c-Jun N-terminal kinase pathway and apoptotic signaling (review).

T. Tan, Yi-Rong Chen, Y. Chen, 2000, International journal of oncology.

Protein Phosphatase 4 Interacts with and Down-regulates Insulin Receptor Substrate 4 following Tumor Necrosis Factor-α Stimulation*

J. Qin, K. Mihindukulasuriya, T. Tan, 2004, Journal of Biological Chemistry.

Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases

P. Lyu, T. Tan, H. Chuang, 2020, International journal of molecular sciences.

Protein Phosphatase X Interacts with c-Rel and Stimulates c-Rel/Nuclear Factor κB Activity*

M. C. Hu, K. Mihindukulasuriya, M. Hu, 1998, The Journal of Biological Chemistry.

MAP4K4 and IL-6+ Th17 cells play important roles in non-obese type 2 diabetes

T. Tan, H. Chuang, 2017, Journal of Biomedical Science.

The phosphatase JKAP/DUSP22 inhibits T-cell receptor signalling and autoimmunity by inactivating Lck

J. Belmont, T. Tan, Xiaohong Wang, 2014, Nature Communications.

Expression of v-src in T cells correlates with nuclear expression of NF-kappa B.

J. O’Shea, T. Tan, N. Rice, 1994, Journal of immunology.

Caspase-mediated cleavage of actin-binding and SH3-domain-containing proteins cortactin, HS1, and HIP-55 during apoptosis.

T. Tan, B. John, Y. Chen, 2001, Biochemical and biophysical research communications.

Caspase-mediated cleavage and functional changes of hematopoietic progenitor kinase 1 (HPK1)

T. Tan, B. Ahmed, C. Meyer, 1999, Oncogene.

Activating Mutations forTransformation byp53Produce aGene Product ThatFormsanhsc7O-p53 Complex withan Altered Half-Life

M. Oren, P. Hinds, C. Finlay, 1988 .

The SH3 Domain-containing Adaptor HIP-55 Mediates c-Jun N-terminal Kinase Activation in T Cell Receptor Signaling*

T. Tan, J. Shui, Z. Yao, 2003, Journal of Biological Chemistry.

Adriamycin activates c-jun N-terminal kinase in human leukemia cells: a relevance to apoptosis.

R. Yu, A. Kong, I. Roninson, 1996, Cancer letters.

PP4 Is Essential for Germinal Center Formation and Class Switch Recombination in Mice

T. Tan, Ming-yu Chen, Guann-Yi Yu, 2014, PloS one.

Protein phosphatase 4 is an essential positive regulator for Treg development, function, and protective gut immunity

T. Tan, J. Shui, Ching‐Yu Huang, 2014, Cell & Bioscience.

Conditional Knockout Mice Reveal an Essential Role of Protein Phosphatase 4 in Thymocyte Development and Pre-T-Cell Receptor Signaling

M. C. Hu, M. Hu, T. Tan, 2006, Molecular and Cellular Biology.

MAP4K3/GLK inhibits Treg differentiation by direct phosphorylating IKKβ and inducing IKKβ-mediated FoxO1 nuclear export and Foxp3 downregulation

T. Tan, H. Chuang, J. Chi, 2022, Theranostics.

SARS‐CoV‐2 spike protein enhances MAP4K3/GLK‐induced ACE2 stability in COVID‐19

T. Tan, Y. Chow, H. Chuang, 2022, EMBO molecular medicine.

Activation of mitogen-activated protein kinases by green tea polyphenols: potential signaling pathways in the regulation of antioxidant-responsive element-mediated phase II enzyme gene expression.

R. Yu, A. Kong, T. Tan, 1997, Carcinogenesis.

Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis.

T. Tan, C. Meyer, Y. Chen, 1996, The Journal of biological chemistry.

Protein Phosphatase 4 Is a Positive Regulator of Hematopoietic Progenitor Kinase 1*

T. Tan, Guisheng Zhou, J. Boomer, 2004, Journal of Biological Chemistry.

TRAF2-mediated Lys63-linked ubiquitination of DUSP14/MKP6 is essential for its phosphatase activity.

T. Tan, Chia-Yu Yang, L. Chiu, 2016, Cellular signalling.

Induction of Interferon‐γ and Tissue Inflammation by Overexpression of Eosinophil Cationic Protein in T Cells and Exosomes

T. Tan, H. Chuang, Ming-Han Chen, 2021, Arthritis & Rheumatology (Hoboken, N.j.).

Actin-Binding Protein 1 Regulates B Cell Receptor-Mediated Antigen Processing and Presentation in Response to B Cell Receptor Activation1

T. Tan, O. Onabajo, M. Kessels, 2008, The Journal of Immunology.

This information is current as Activation Presentation in Response to B Cell Receptor Receptor-Mediated Antigen Processing and Actin-Binding Protein 1 Regulates B Cell and Wenxia

T. Tan, O. Onabajo, M. Kessels, 2008 .

CD28 signaling causes a sustained down-regulation of I kappa B alpha which can be prevented by the immunosuppressant rapamycin.

T. Tan, J. Lai, J. Lai, 1994, The Journal of biological chemistry.

Tyrosine phosphorylation of Vav stimulates IL-6 production in mast cells by a Rac/c-Jun N-terminal kinase-dependent pathway.

T. Tan, J. S. Song, J. Rivera, 1999, Journal of immunology.

N-Terminal Kinase-Dependent Pathway Rac / c-JunIL-6 Production in Mast Cells by a Tyrosine Phosphorylation of Vav Stimulates

James S. Song, T. Tan, J. Rivera, 1999 .

The Role of c-Jun N-terminal Kinase (JNK) in Apoptosis Induced by Ultraviolet C and γ Radiation

T. Tan, D. Templeton, Xiaoping Wang, 1996, The Journal of Biological Chemistry.

KB Site-Dependent Activation of the Interleukin-2 Receptor CL-Chain Gene Promoter by Human c-Rel

D. Longo, H. Young, T. Tan, 2003 .

Kappa B site-dependent activation of the interleukin-2 receptor alpha-chain gene promoter by human c-Rel

D. Longo, A. Sica, H. Young, 1992, Molecular and cellular biology.

Actin-binding protein 1 links B-cell antigen receptors to negative signaling pathways

A. Upadhyaya, T. Tan, O. Onabajo, 2014, Proceedings of the National Academy of Sciences.

HIP-55 Is Important for T-Cell Proliferation, Cytokine Production, and Immune Responses

T. Tan, B. Zheng, J. Shui, 2005, Molecular and Cellular Biology.

The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells

T. Tan, Xiaohong Wang, Ju-Pi Li, 2011, Nature Immunology.

Cutting Edge: γδ T Cells Provide Help to B Cells with Altered Clonotypes and Are Capable of Inducing Ig Gene Hypermutation1

T. Tan, B. Zheng, Shuhua Han, 2003, The Journal of Immunology.

Cutting edge: gamma delta T cells provide help to B cells with altered clonotypes and are capable of inducing Ig gene hypermutation.

T. Tan, B. Zheng, Shuhua Han, 2003, Journal of immunology.

Genomic structure of the mouse PP4 gene: a developmentally regulated protein phosphatase.

M. C. Hu, K. Mihindukulasuriya, T. Tan, 2001, Gene.

Purification and characterization of multiple nuclear factors that bind to the TAX-inducible enhancer within the human T-cell leukemia virus type 1 long terminal repeat

M. Horikoshi, R. Roeder, T. Tan, 1989, Molecular and cellular biology.

c-Jun N-terminal kinase mediates apoptotic signaling induced by N-(4-hydroxyphenyl)retinamide.

G. Zhou, T. Tan, Y. Chen, 1999, Molecular pharmacology.

Lack of correlation in JNK activation and p53-dependent Fas expression induced by apoptotic stimuli.

T. Tan, Yi-Rong Chen, Y. Chen, 1999, Biochemical and biophysical research communications.

Utilization of signal transduction pathway by the human T-cell leukemia virus type I transcriptional activator tax

R. Roeder, T. Tan, R. Jia, 1989, Journal of virology.

DUSP11 Attenuates Lipopolysaccharide-Induced Macrophage Activation by Targeting TAK1

T. Tan, H. Chuang, Chia-Yu Yang, 2020, The Journal of Immunology.

The germinal center kinase (GCK)-related protein kinases HPK1 and KHS are candidates for highly selective signal transducers of Crk family adapter proteins

J. Blenis, S. Feller, J. Groffen, 1998, Oncogene.

Attenuation of T Cell Receptor Signaling by Serine Phosphorylation-mediated Lysine 30 Ubiquitination of SLP-76 Protein*

T. Tan, Xiaohong Wang, Ju-Pi Li, 2012, The Journal of Biological Chemistry.

Expression and characterization of the trans-activating protein Tax of human T-cell leukemia virus type I in Saccharomyces cerevisiae

T. Tan, L. Wu, S. I. Shahied, 1992, Journal of virology.

Development and trends of biosurfactant analysis and purification using rhamnolipids as an example

M. Franzreb, T. Tan, G. Brenner-Weiss, 2008, Analytical and bioanalytical chemistry.

Activation of p38 and c-Jun N-terminal Kinase Pathways and Induction of Apoptosis by Chelerythrine Do Not Require Inhibition of Protein Kinase C*

R. Yu, S. Mandlekar, A. Kong, 2000, The Journal of Biological Chemistry.

Activation of Mitogen-activated Protein Kinase Pathways Induces Antioxidant Response Element-mediated Gene Expression via a Nrf2-dependent Mechanism*

Y. Mo, R. Yu, A. Kong, 2000, The Journal of Biological Chemistry.

Hematopoietic progenitor kinase 1 negatively regulates T cell receptor signaling and T cell–mediated immune responses

T. Tan, Jun Xu, Guisheng Zhou, 2007, Nature Immunology.

Prediction of early hepatocellular carcinoma recurrence using germinal center kinase-like kinase

T. Tan, Ting Chang, H. Tsai, 2016, Oncotarget.

Down-regulation of the c-Jun N-terminal kinase (JNK) phosphatase M3/6 and activation of JNK by hydrogen peroxide and pyrrolidine dithiocarbamate

T. Tan, A. Shrivastava, Yi-Rong Chen, 2001, Oncogene.

Germinal center kinase-like kinase overexpression in T cells as a novel biomarker in rheumatoid arthritis.

T. Tan, W. Hung, T. Lan, 2013, Arthritis and rheumatism.

Identification of a gut microbiota member that ameliorates DSS-induced colitis in intestinal barrier enhanced Dusp6-deficient mice.

H. Juan, Yu-Chieh Liao, T. Tan, 2021, Cell reports.

Hematopoietic Progenitor Kinase 1 Is a Component of Transforming Growth Factor β-induced c-Jun N-terminal Kinase Signaling Cascade*

T. Tan, Guisheng Zhou, Z. Yao, 1999, The Journal of Biological Chemistry.

Epigenetic regulation of HGK/MAP4K4 in T cells of type 2 diabetes patients

Jun-Sing Wang, W. Sheu, I. Lee, 2016, Oncotarget.

HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to insulin resistance

M. Xie, T. Tan, Xiaohong Wang, 2014, Nature Communications.

Expression of MAP4K4 Is Associated with Worse Prognosis in Patients with Stage II Pancreatic Ductal Adenocarcinoma

Stanley R Hamilton, Douglas B. Evans, A. Rashid, 2008, Clinical Cancer Research.

Interaction of Hematopoietic Progenitor Kinase 1 with Adapter Proteins Crk and CrkL Leads to Synergistic Activation of c-Jun N-Terminal Kinase

S. Feller, T. Tan, C. Meyer, 1999, Molecular and Cellular Biology.

DUSP22 suppresses prostate cancer proliferation by targeting the EGFR‐AR axis

T. Tan, S. Yeh, Wen-Jye Lin, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

MAP4K3/GLK in autoimmune disease, cancer and aging

T. Tan, H. Chuang, 2019, Journal of Biomedical Science.

A Novel Human STE20-related Protein Kinase, HGK, That Specifically Activates the c-Jun N-terminal Kinase Signaling Pathway*

T. Tan, K. Diener, A. Brown, 1999, The Journal of Biological Chemistry.

Caspase-9-induced Mitochondrial Disruption through Cleavage of Anti-apoptotic BCL-2 Family Members*

T. Tan, Min Chen, Jin Wang, 2007, Journal of Biological Chemistry.

MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo

M. Entman, M. Xie, G. Taffet, 2019, Cell stem cell.

MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo

M. Entman, M. Xie, G. Taffet, 2019, Cell stem cell.

The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation.

R. Davis, T. Tan, X. Wang, 1996, The Journal of biological chemistry.

Phenylethyl Isothiocyanate Induces Apoptotic Signaling via Suppressing Phosphatase Activity against c-Jun N-terminal Kinase*

A. Kong, T. Tan, Yi-Rong Chen, 2002, The Journal of Biological Chemistry.

Cell cycle regulation of c-Jun N-terminal kinase activity at the centrosomes.

T. Tan, D. Goodrich, B. Brinkley, 2001, Biochemical and biophysical research communications.

Role of c-Jun N-terminal kinase 1 (JNK1) in cell cycle checkpoint activated by the protease inhibitor N-acetyl-leucinyl-leucinyl-norleucinal

W. Rom, T. Tan, K. Tchou-Wong, 1999, Oncogene.

Murine p38-δ Mitogen-activated Protein Kinase, a Developmentally Regulated Protein Kinase That Is Activated by Stress and Proinflammatory Cytokines*

M. C. Hu, A. Mikhail, M. Hu, 1999, The Journal of Biological Chemistry.

Activation of Stress-activated Protein Kinases/c-Jun N-terminal Protein Kinases (SAPKs/JNKs) by a Novel Mitogen-activated Protein Kinase Kinase (MKK7)*

H. Nishina, J. Penninger, C. Hui, 1997, The Journal of Biological Chemistry.

Activation of the Hematopoietic Progenitor Kinase-1 (HPK1)-dependent, Stress-activated c-Jun N-terminal Kinase (JNK) Pathway by Transforming Growth Factor β (TGF-β)-activated Kinase (TAK1), a Kinase Mediator of TGF β Signal Transduction*

M. C. Hu, M. Hu, T. Tan, 1997, The Journal of Biological Chemistry.

Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase.

T. Tan, X. Wang, K. Diener, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade.

M. C. Hu, M. C. Hu, T. Tan, 1996, Genes & development.

PP4 deficiency leads to DNA replication stress that impairs immunoglobulin class switch efficiency

T. Tan, Ming-yu Chen, Wen-Jye Lin, 2018, Cell Death & Differentiation.

DUSPs, to MAP kinases and beyond

T. Tan, Ching‐Yu Huang, 2012, Cell & Bioscience.

DUSP4 deficiency enhances CD25 expression and CD4+ T‐cell proliferation without impeding T‐cell development

T. Tan, Ching‐Yu Huang, Yu-Chun Lin, 2012, European journal of immunology.

Histone deacetylase 3 (HDAC3) activity is regulated by interaction with protein serine/threonine phosphatase 4.

E. Seto, T. Tan, X. Zhang, 2005, Genes & development.

Regulation of Dual-Specificity Phosphatase (DUSP) Ubiquitination and Protein Stability

T. Tan, H. Chuang, Hsueh-Fen Chen, 2019, International journal of molecular sciences.

Differential regulation of mitogen-activated protein kinases by microtubule-binding agents in human breast cancer cells

R. Yu, S. Mandlekar, A. Kong, 1999, Oncogene.

Macrophage migration inhibitory factor of the parasitic nematode Trichinella spiralis.

L. Pearl, T. Tan, S. Roe, 2001, The Biochemical journal.

Effect of CD28 signal transduction on c-Rel in human peripheral blood T cells

T. Tan, J. Lai, N. Rice, 1994, Molecular and cellular biology.

RelA is a potent transcriptional activator of the CD28 response element within the interleukin 2 promoter

T. Tan, J. Bruder, J. Lai, 1995, Molecular and cellular biology.

Germinal center kinase-like kinase (GLK/MAP4K3) expression is increased in adult-onset Still's disease and may act as an activity marker

T. Tan, W. Hung, Yi-Ming Chen, 2012, BMC Medicine.

The Serine/Threonine Phosphatase PP4 Is Required for Pro-B Cell Development through Its Promotion of Immunoglobulin VDJ Recombination

M. Reth, T. Tan, Ming-yu Chen, 2013, PloS one.

Downregulation of the phosphatase JKAP/DUSP22 in T cells as a potential new biomarker of systemic lupus erythematosus nephritis

T. Tan, W. Hung, Ju-Pi Li, 2016, Oncotarget.

The Dual Specificity JKAP Specifically Activates the c-Jun N-terminal Kinase Pathway*

J. Belmont, N. Copeland, D. Gilbert, 2002, The Journal of Biological Chemistry.

Protein Phosphatase 4 Is Involved in Tumor Necrosis Factor-α-induced Activation of c-Jun N-terminal Kinase*

M. C. Hu, K. Mihindukulasuriya, M. Hu, 2002, The Journal of Biological Chemistry.

Proteasome-mediated degradation and functions of hematopoietic progenitor kinase 1 in pancreatic cancer.

Douglas B. Evans, Huamin Wang, J. Abbruzzese, 2009, Cancer research.

Biochemical and biological characterization of a neuroendocrine‐associated phosphatase

T. Tan, Jiz-Yuh Wang, Yi-Rong Chen, 2006, Journal of neurochemistry.

Germline transmission and efficient DNA recombination in mouse embryonic stem cells mediated by adenoviral‐Cre transduction

T. Tan, J. Shui, 2004, Genesis.

JNK Pathway-associated Phosphatase Dephosphorylates Focal Adhesion Kinase and Suppresses Cell Migration*

T. Tan, Ju-Pi Li, Yu-Ning Fu, 2009, The Journal of Biological Chemistry.

GLK-IKKβ signaling induces dimerization and translocation of the AhR-RORγt complex in IL-17A induction and autoimmune disease

T. Tan, H. Chuang, Ching‐Yi Tsai, 2018, Science Advances.

DUSPs, to MAP kinases and beyond

T. Tan, Ching‐Yu Huang, 2012, Cell & Bioscience.

MAP4K3/GLK in autoimmune disease, cancer and aging

T. Tan, H. Chuang, 2019, Journal of Biomedical Science.

Expression of MAP 4 K 4 Is Associated withWorse Prognosis in Patients with Stage II Pancreatic Ductal Adenocarcinoma

Douglas B. Evans, A. Rashid, R. Hwang, 2008 .

A Novel Src Homology 3 Domain-containing Adaptor Protein, HIP-55, That Interacts with Hematopoietic Progenitor Kinase 1*

T. Tan, Guisheng Zhou, D. Ensenat, 1999, The Journal of Biological Chemistry.

Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis

T. Tan, H. Chuang, Y. Yeh, 2023, BMC Medicine.

AhR–ROR-γt complex is a therapeutic target for MAP4K3/GLKhighIL-17Ahigh subpopulation of systemic lupus erythematosus

T. Tan, W. Hung, Yi-Ming Chen, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Hematopoietic progenitor kinase-1 (HPK1) stress response signaling pathway activates IkappaB kinases (IKK-alpha/beta) and IKK-beta is a developmentally regulated protein kinase.

M. C. Hu, A. Mikhail, T. Tan, 1999, Oncogene.

DUSP6 mediates T cell receptor-engaged glycolysis and restrains TFH cell differentiation

T. Tan, Ming-yu Chen, C. Pan, 2018, Proceedings of the National Academy of Sciences.

The interleukin 2 CD28-responsive complex contains at least three members of the NF kappa B family: c-Rel, p50, and p65.

A. Sica, H. Young, T. Tan, 1993, Proceedings of the National Academy of Sciences of the United States of America.

DUSP6 Deficiency Attenuates Neurodegeneration after Global Cerebral Ischemia

T. Tan, H. Chuang, W. Chou, 2023, International journal of molecular sciences.

MAP4K3/GLK promotes lung cancer metastasis by phosphorylating and activating IQGAP1.

P. Lyu, T. Tan, C. Teng, 2019, Cancer research.

Down-regulation of B Cell Receptor Signaling by Hematopoietic Progenitor Kinase 1 (HPK1)-mediated Phosphorylation and Ubiquitination of Activated B Cell Linker Protein (BLNK)*

T. Tan, Hongbo Hu, Xiaohong Wang, 2012, The Journal of Biological Chemistry.

Activation of Signal Transduction Kinases by Tamoxifen

R. Yu, A. Kong, T. Tan, 1997, Pharmaceutical Research.

Hematopoietic progenitor kinase 1 inhibits the development and progression of pancreatic intraepithelial neoplasia

A. Maitra, Xiaoping Su, T. Tan, 2023, The Journal of clinical investigation.

Functional interactions of HPK1 with adaptor proteins

T. Tan, J. Boomer, 2005, Journal of cellular biochemistry.

RBM4a-SRSF3-MAP4K4 Splicing Cascade Constitutes a Molecular Mechanism for Regulating Brown Adipogenesis

Yu-Chih Liang, T. Tan, Jung-Chun Lin, 2018, International journal of molecular sciences.

MAP4K4 and IL-6+ Th17 cells play important roles in non-obese type 2 diabetes

T. Tan, H. Chuang, 2017, Journal of Biomedical Science.

p38 MAP kinase interacts with and stabilizes pancreatic and duodenal homeobox-1.

J. Qin, T. Tan, F. Brunicardi, 2013, Current molecular medicine.

Deficiency in VHR/DUSP3, a suppressor of focal adhesion kinase, reveals its role in regulating cell adhesion and migration

T. Tan, W. Chao, H. Chuang, 2017, Oncogene.

ACE2 in chronic disease and COVID-19: gene regulation and post-translational modification

T. Tan, H. Chuang, Chia-Wen Wang, 2023, Journal of Biomedical Science.

SARS‐CoV ‐2 spike protein enhances MAP4K3 / GLK ‐induced ACE2 stability in COVID ‐19

T. Tan, Y. Chow, H. Chuang, 2022, EMBO Molecular Medicine.

GLK/MAP4K3 overexpression associates with recurrence risk for non-small cell lung cancer

T. Tan, Ju-Pi Li, H. Chuang, 2016, Oncotarget.

Single-cell RNA sequencing uncovers the individual alteration of intestinal mucosal immunocytes in Dusp6 knockout mice

H. Juan, T. Tan, Wen-Jye Lin, 2022, iScience.

Dual-Specificity Phosphatase 14 (DUSP14/MKP6) Negatively Regulates TCR Signaling by Inhibiting TAB1 Activation

T. Tan, Ju-Pi Li, Der-Yuan Chen, 2014, The Journal of Immunology.

Signaling by Inhibiting TAB1 Activation (DUSP14/MKP6) Negatively Regulates TCR Dual-Specificity Phosphatase 14

T. Tan, Ju-Pi Li, Der-Yuan Chen, 2014 .

Abstract 1949: The Protein Kinase MAP4K4 Is Activated in Failing Human Hearts and Mediates Cardiomyocyte Apoptosis in Experimental Models, in vitro and in vivo

M. Entman, M. Xie, Dou-xia Zhang, 2007 .

Development and trends of biosurfactant analysis and purification using rhamnolipids as an example

T. Tan, G. Brenner-Weiss, M. Franzreb, 2008, Analytical and bioanalytical chemistry.