N. Fox

发表

Fine-tuning p53 activity through C-terminal modification significantly contributes to HSC homeostasis and mouse radiosensitivity.

G. Wahl, A. Balmain, H. Piwnica-Worms, 2011, Genes & development.

Thrombopoietin (TPO) induces c-myc expression through a PI3K- and MAPK-dependent pathway that is not mediated by Akt, PKCzeta or mTOR in TPO-dependent cell lines and primary megakaryocytes.

N. Fox, K. Kaushansky, A. Geddis, 2006, Cellular signalling.

The Roles of Phosphatidylinositol 3-Kinase and Protein Kinase Cζ for Thrombopoietin-induced Mitogen-activated Protein Kinase Activation in Primary Murine Megakaryocytes*

Y. Miyakawa, N. Fox, K. Kaushansky, 2001, The Journal of Biological Chemistry.

Interferon-alpha directly represses megakaryopoiesis by inhibiting thrombopoietin-induced signaling through induction of SOCS-1.

Y. Miyakawa, N. Fox, K. Kaushansky, 2000, Blood.

Thrombopoietin enhances expression of vascular endothelial growth factor (VEGF) in primitive hematopoietic cells through induction of HIF-1alpha.

N. Fox, K. Kaushansky, K. Kirito, 2004, Blood.

JAK2V617F-positive endothelial cells contribute to clotting abnormalities in myeloproliferative neoplasms

N. Fox, K. Kaushansky, Junmei Chen, 2014, Proceedings of the National Academy of Sciences.

Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development.

V. Broudy, N. Fox, K. Kaushansky, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Murine thrombopoietin mRNA levels are modulated by platelet count.

N. Fox, K. Kaushansky, J. McCarty, 1995, Blood.

Derivation and preliminary characterisation of adriamycin resistant lines of human lung cancer cells.

N. Bleehen, N. Fox, P. Twentyman, 1986, British Journal of Cancer.

Drug resistance in human lung cancer cell lines: cross-resistance studies and effects of the calcium transport blocker, verapamil.

N. Bleehen, N. Fox, P. Twentyman, 1986, International journal of radiation oncology, biology, physics.

Characterisation of a mouse tumour cell line with in vitro derived resistance to verapamil.

N. Fox, P. Twentyman, K. Wright, 1990, British Journal of Cancer.

Lineage-specific growth factors can compensate for stem and progenitor cell deficiencies at the postprogenitor cell level: an analysis of doubly TPO- and G-CSF receptor-deficient mice.

N. Fox, K. Kaushansky, W. Liles, 2002, Blood.

Phosphatidylinositol 3-Kinase Is Necessary but Not Sufficient for Thrombopoietin-induced Proliferation in Engineered Mpl-bearing Cell Lines as Well as in Primary Megakaryocytic Progenitors*

N. Fox, K. Kaushansky, A. Geddis, 2001, The Journal of Biological Chemistry.

Chemosensitivity testing of fresh leukaemia cells using the MTT colorimetric assay

N. Fox, P. Twentyman, J. Rees, 1989, British journal of haematology.

Roles of focal adhesion kinase (FAK) in megakaryopoiesis and platelet function: studies using a megakaryocyte lineage specific FAK knockout.

N. Prévost, N. Fox, K. Kaushansky, 2008, Blood.

Kinetics of endomitosis in primary murine megakaryocytes

N. Fox, K. Kaushansky, C. E. Carow, 2001, Journal of cellular physiology.

Cyclosporin A and its analogues as modifiers of adriamycin and vincristine resistance in a multi-drug resistant human lung cancer cell line.

N. Fox, P. Twentyman, D. J. White, 1987, British Journal of Cancer.

enhances thrombopoietin-induced megakaryopoiesis

N. Fox, K. Kaushansky, 2005 .

Engagement of integrin α4β1 enhances thrombopoietin-induced megakaryopoiesis

N. Fox, K. Kaushansky, 2005 .

The in vitro effects and cross-resistance patterns of some novel anthracyclines.

N. Bleehen, P. Workman, N. Fox, 1986, British Journal of Cancer.

Thrombopoietin stimulates Hoxb4 expression: an explanation for the favorable effects of TPO on hematopoietic stem cells.

N. Fox, K. Kaushansky, K. Kirito, 2003, Blood.

favorable effects of TPO on hematopoietic stem cells Thrombopoietin stimulates HoxB4 expression: an explanation for the

N. Fox, K. Kaushansky, K. Kirito, 2013 .

Thrombopoietin Induces HOXA9 Nuclear Transport in Immature Hematopoietic Cells: Potential Mechanism by Which the Hormone Favorably Affects Hematopoietic Stem Cells

N. Fox, K. Kaushansky, K. Kirito, 2004, Molecular and Cellular Biology.

Thrombopoietin stimulates colony-forming unit-megakaryocyte proliferation and megakaryocyte maturation independently of cytokines that signal through the gp130 receptor subunit.

V. Broudy, N. Fox, K. Kaushansky, 1996, Blood.

Thrombopoietin stimulates Hoxb 4 expression : an explanation for the favorable effects of TPO on hematopoietic stem cells

N. Fox, K. Kaushansky, K. Kirito, 2003 .

Blocking the alpha 4 integrin-paxillin interaction selectively impairs mononuclear leukocyte recruitment to an inflammatory site.

N. Fox, K. Kaushansky, G. Silverman, 2006, The Journal of clinical investigation.

Lineage-speciﬁc growth factors can compensate for stem and progenitor cell deﬁciencies at the postprogenitor cell level: an analysis of doubly TPO- and G-CSF receptor–deﬁcient mice

N. Fox, K. Kaushansky, W. Liles, 2002 .

Cytoprotective doses of erythropoietin or carbamylated erythropoietin have markedly different procoagulant and vasoactive activities.

P. Ghezzi, A. Cerami, N. Fox, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Interferon-alpha directly represses megakaryopoiesis by inhibiting thrombopoietin-induced signaling through induction of SOCS-1.

Y. Miyakawa, N. Fox, K. Kaushansky, 2000, Blood.

Establishment and characterisation of cell lines from patients with lung cancer (predominantly small cell carcinoma).

N. Bleehen, P. Workman, N. Fox, 1985, British Journal of Cancer.

Thrombopoietin signal transduction in purified murine megakaryocytes.

N. Fox, K. Kaushansky, J. Drachman, 1997, Blood.

The effect of thrombopoietin on the proliferation and differentiation of murine hematopoietic stem cells.

V. Broudy, N. Fox, K. Kaushansky, 1996, Blood.

Thrombopoietin expands hematopoietic stem cells after transplantation.

N. Fox, K. Kaushansky, T. Papayannopoulou, 2002, The Journal of clinical investigation.

Compound heterozygous c-Mpl mutations in a child with congenital amegakaryocytic thrombocytopenia: functional characterization and a review of the literature.

N. Fox, A. Geddis, I. Hitchcock, 2009, Experimental hematology.

PI3K/Akt/FOXO3a pathway contributes to thrombopoietin-induced proliferation of primary megakaryocytes in vitro and in vivo via modulation of p27Kip1

T. Nakao, N. Fox, K. Kaushansky, 2008, Cell cycle.

A comparison of clonogenic and radionuclide uptake assays for determining the radiation response of human small-cell lung cancer xenografts and cell lines.

N. Fox, P. Twentyman, 1987, The British journal of radiology.

F104S c-Mpl responds to a transmembrane domain-binding thrombopoietin receptor agonist: proof of concept that selected receptor mutations in congenital amegakaryocytic thrombocytopenia can be stimulated with alternative thrombopoietic agents.

N. Fox, A. Geddis, Jihyang Lim, 2010, Experimental hematology.

Endomitotic Megakaryocytes that Form a Bipolar Spindle Exhibit Cleavage Furrow Ingression Followed by Furrow Regression

N. Fox, K. Kaushansky, A. Geddis, 2007, Cell cycle.

Engagement of integrin alpha4beta1 enhances thrombopoietin-induced megakaryopoiesis.

N. Fox, K. Kaushansky, 2005, Experimental Hematology.

The Mpl receptor expressed on endothelial cells does not contribute significantly to the regulation of circulating thrombopoietin levels.

N. Fox, K. Kaushansky, A. Geddis, 2006, Experimental hematology.