Vaibhav Sidarala

发表

Exposure to chronic hyperglycemic conditions results in Ras-related C3 botulinum toxin substrate 1 (Rac1)-mediated activation of p53 and ATM kinase in pancreatic β-cells

Vaibhav Sidarala, A. Kowluru, 2017, Apoptosis.

The Regulatory Roles of Mitogen-Activated Protein Kinase (MAPK) Pathways in Health and Diabetes: Lessons Learned from the Pancreatic β-Cell.

Vaibhav Sidarala, A. Kowluru, 2017, Recent patents on endocrine, metabolic & immune drug discovery.

Mitofusin 1 and 2 regulation of mitochondrial DNA content is a critical determinant of glucose homeostasis

B. Kaufman, Vaibhav Sidarala, E. Walker, 2022, Nature Communications.

VAV2, a guanine nucleotide exchange factor for Rac1, regulates glucose-stimulated insulin secretion in pancreatic beta cells

Vaibhav Sidarala, A. Kowluru, C. Vlaar, 2015, Diabetologia.

An intrinsically disordered protein region encoded by the human disease gene CLEC16A regulates mitophagy

D. Klionsky, Vaibhav Sidarala, Debashish Sahu, 2022, Autophagy.

NSC23766, a Known Inhibitor of Tiam1-Rac1 Signaling Module, Prevents the Onset of Type 1 Diabetes in the NOD Mouse Model

Vaibhav Sidarala, A. Kowluru, R. Veluthakal, 2016, Cellular Physiology and Biochemistry.

Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues

Stephen C. J. Parker, L. Sussel, Nathan Lawlor, 2024, bioRxiv.

Mitofusins 1 and 2 collaborate to fuel pancreatic beta cell insulin release via regulation of both mitochondrial structure and DNA content

B. Kaufman, Vaibhav Sidarala, Jie Zhu, 2021, Diabetes.

Beta-cell Cre expression and reduced Ins1 gene dosage protect mice from type 1 diabetes

James D. Johnson, Vaibhav Sidarala, M. Horwitz, 2022, bioRxiv.

Mechanisms Of Pancreatic Beta Cell Dysfunction In Diabetes

Vaibhav Sidarala, 2016 .

Mitophagy protects beta cells from inflammatory damage in diabetes

L. Satin, Vaibhav Sidarala, J. Corbett, 2020, bioRxiv.

Mitophagy protects β cells from inflammatory damage in diabetes

L. Satin, Vaibhav Sidarala, J. Corbett, 2020 .

Reciprocal regulatory balance within the CLEC16A-RNF41 mitophagy complex depends on an intrinsically disordered protein region.

D. Klionsky, Vaibhav Sidarala, Debashish Sahu, 2023, The Journal of biological chemistry.

The human disease gene CLEC16A encodes an intrinsically disordered protein region required for mitochondrial quality control

S. Schnell, D. Klionsky, Vaibhav Sidarala, 2021, bioRxiv.

Mitochondrial metabolism and dynamics in pancreatic beta cell glucose sensing.

G. Rutter, B. Kaufman, Vaibhav Sidarala, 2023, The Biochemical journal.

Phagocyte-like NADPH oxidase (Nox2) promotes activation of p38MAPK in pancreatic β-cells under glucotoxic conditions: Evidence for a requisite role of Ras-related C3 botulinum toxin substrate 1 (Rac1).

P. Newsholme, Vaibhav Sidarala, A. Kowluru, 2015, Biochemical pharmacology.

EHT 1864, a small molecule inhibitor of Ras-related C3 botulinum toxin substrate 1 (Rac1), attenuates glucose-stimulated insulin secretion in pancreatic β-cells.

Vaibhav Sidarala, A. Kowluru, R. Veluthakal, 2015, Cellular signalling.

Glucotoxic and diabetic conditions induce caspase 6-mediated degradation of nuclear lamin A in human islets, rodent islets and INS-1 832/13 cells

Vaibhav Sidarala, A. Kowluru, Syeda Khadija, 2014, Apoptosis.

Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis

M. Cnop, P. Arvan, Vaibhav Sidarala, 2024, Protein science : a publication of the Protein Society.