A. Kowluru

A. Kowluru, Mirabela Hali, Suhadinie Gamage, 2022, Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.

CARD9 Mediates Pancreatic Islet Beta-Cell Dysfunction Under the Duress of Hyperglycemic Stress

A. Kowluru, Mirabela Hali, Suhadinie Gamage, 2022, Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.

RACking up ceramide‐induced islet &bgr;‐cell dysfunction

A. Kowluru, R. Kowluru, 2018, Biochemical pharmacology.

Increased Phagocyte-Like NADPH Oxidase and Reactive Oxygen Species Generation in Type 2 Diabetic ZDF Rat and Human Islets Role of Rac1–Jun NH2-Terminal Kinase 1/2 Signaling Pathway in Mitochondrial Dysregulation in the Diabetic Islet

A. Kowluru, C. Rhodes, R. Kowluru, 2011 .

Deoxysphingolipids: β-Cell, Beware of These New Kids on the Block

A. Kowluru, 2014, Diabetes.

P-Rex1 Mediates Glucose-Stimulated Rac1 Activation and Insulin Secretion in Pancreatic β-Cells

A. Kowluru, V. Thamilselvan, Suhadinie Gamage, 2020, Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.

Arf nucleotide binding site opener [ARNO] promotes sequential activation of Arf6, Cdc42 and Rac1 and insulin secretion in INS 832/13 β-cells and rat islets.

A. Kowluru, C. Rhodes, Bhavaani Jayaram, 2011, Biochemical pharmacology.

Small G proteins in islet beta-cell function.

A. Kowluru, 2010, Endocrine reviews.

Protein Farnesylation–Dependent Raf/Extracellular Signal–Related Kinase Signaling Links to Cytoskeletal Remodeling to Facilitate Glucose-Induced Insulin Secretion in Pancreatic β-Cells

A. Kowluru, C. Rhodes, R. Veluthakal, 2010, Diabetes.

Small G Proteins in Islet (cid:1) -Cell Function

A. Kowluru, 2010 .

Protein farnesylation in glucose-induced ERK activation and insulin secretion. Protein Farnesylation-Dependent Raf/ERK Signaling Links To Cytoskeletal Remodeling to Facilitate Glucose-Induced Insulin Secretion in Pancreatic ß-Cells Short title: Protein farnesylation in glucose-induced ERK activation

A. Kowluru, C. Rhodes, R. Veluthakal, 2010 .

Glucose activates prenyltransferases in pancreatic islet β -cells

A. Kowluru, M. Goalstone, Vasudeva G. Kamath, 2010 .

Protein Farnesylation-Dependent Raf/ERK Signaling Links To Cytoskeletal Remodeling to Facilitate Glucose-Induced Insulin Secretion in Pancreatic ß-Cells Short title: Protein farnesylation in glucose-induced ERK activation and insulin secretion.

A. Kowluru, C. Rhodes, R. Veluthakal, 2010 .

Glucose activates prenyltransferases in pancreatic islet beta-cells.

A. Kowluru, M. Goalstone, Vasudeva G. Kamath, 2010, Biochemical and biophysical research communications.

Protein prenylation in glucose-induced insulin secretion from the pancreatic islet β cell: a perspective

A. Kowluru, 2007, Journal of cellular and molecular medicine.

Protein and Vesicle Trafficking , Cytoskeleton Biologically active lipids promote trafficking and membrane association of Rac 1 in insulin-secreting INS 832 / 13 cells

A. Kowluru, Hitchintan Kaur, R. Veluthakal, 2007 .

Rho guanosine diphosphate-dissociation inhibitor plays a negative modulatory role in glucose-stimulated insulin secretion.

A. Kowluru, R. Veluthakal, 2005, Diabetes.

Mastoparan-induced insulin secretion from insulin-secreting betaTC3 and INS-1 cells: evidence for its regulation by Rho subfamily of G proteins.

A. Kowluru, Jingsong Li, R. Silver, 2003, Endocrinology.

Regulatory roles for small G proteins in the pancreatic beta-cell: lessons from models of impaired insulin secretion.

A. Kowluru, 2003, American journal of physiology. Endocrinology and metabolism.

Carboxylmethylation of the catalytic subunit of protein phosphatase 2A in insulin-secreting cells: evidence for functional consequences on enzyme activity and insulin secretion.

M. Rabaglia, S. Seavey, A. Kowluru, 1996, Endocrinology.

Novel Roles for the Rho Subfamily of GTP‐Binding Proteins in Succinate‐Induced Insulin Secretion from βTC3 Cells: Further Evidence in Support of the Succinate Mechanism of Insulin Release

A. Kowluru, M. Tannous, Hai-Qing Chen, 2003, Endocrine research.

Protein glycation: effects upon protein recognition by the proximal tubule.

A. Kowluru, R. Kowluru, S. Solomon, 1992, Life Science.

Calcium–Calmodulin-Dependent Myosin Phosphorylation by Pancreatic Islets

A. Kowluru, M. MacDonald, Anjaneyulu Kowluru, 1982, Diabetes.

IL-1beta-induced iNOS expression, NO release and loss in metabolic cell viability are resistant to inhibitors of ceramide synthase and sphingomyelinase in INS 832/13 cells.

A. Kowluru, R. Veluthakal, G. R. Jangati, 2006, JOP : Journal of the pancreas.

High glucose exposure promotes activation of protein phosphatase 2A in rodent islets and INS-1 832/13 β-cells by increasing the posttranslational carboxylmethylation of its catalytic subunit.

A. Kowluru, B. Wadzinski, S. Ramanadham, 2014, Endocrinology.

Novel regulatory roles for protein phosphatase-2A in the islet β cell

A. Kowluru, 2005 .

Glucotoxic conditions induce endoplasmic reticulum stress to cause caspase 3 mediated lamin B degradation in pancreatic β-cells: protection by nifedipine.

A. Kowluru, D. Arora, K. Syeda, 2013, Biochemical pharmacology.

Small elevations of glucose concentration redirect and amplify the synthesis of guanosine 5'-triphosphate in rat islets.

M. Rabaglia, A. Kowluru, S. Metz, 1993, The Journal of clinical investigation.

Further evidence for the regulation of acetyl-CoA carboxylase activity by a glutamate- and magnesium-activated protein phosphatase in the pancreatic β cell

A. Kowluru, R. Palanivel, R. Veluthakal, 2005, Endocrine.

Localization of a nuclear serine/threonine protein phosphatase in insulin-secreting INS-1 cells: potential regulation by IL-1β

A. Kowluru, B. Wadzinski, R. Veluthakal, 2006, Apoptosis.

Activation of acetyl-CoA carboxylase by a glutamate- and magnesium-sensitive protein phosphatase in the islet beta-cell.

A. Kowluru, C. Stefanelli, H. Q. Chen, 2001, Diabetes.

Purine Nucleotide- and Sugar Phosphate-Induced Inhibition of the Carboxyl Methylation and Catalysis of Protein Phosphatase-2A in Insulin-Secreting Cells: Protection by Divalent Cations

A. Kowluru, S. Metz, 1998, Bioscience reports.

Evidence for glucose-responsive and -unresponsive pools of phospholipid in pancreatic islets.

A. Kowluru, L. Hokin, R. Rana, 1985, The Journal of biological chemistry.

Subcellular Localization and Characterization of Nucleoside Diphosphate Kinase in Rat Retina: Effect of Diabetes

A. Kowluru, R. Kowluru, 1998, Bioscience reports.

Regulation of guanine-nucleotide binding proteins in islet subcellular fractions by phospholipase-derived lipid mediators of insulin secretion.

A. Kowluru, S. Metz, 1994, Biochimica et biophysica acta.

A defect late in stimulus-secretion coupling impairs insulin secretion in Goto-Kakizaki diabetic rats.

M. Rabaglia, A. Kowluru, S. Metz, 1999, Diabetes.

Small molecular weight G-protein, H-Ras, and retinal endothelial cell apoptosis in diabetes

A. Kowluru, R. Kowluru, M. Kanwar, 2007, Molecular and Cellular Biochemistry.

L-threo-C6-pyridinium-ceramide Bromide, a Novel Cationic Ceramide, Induces NADPH Oxidase Activation, Mitochondrial Dysfunction and Loss in Cell Viability in INS 832/13 β-cells

A. Kowluru, B. Ogretmen, Z. Szulc, 2012, Cellular Physiology and Biochemistry.

Mitochondrial Function / Dysfunction in Health and Disease Phagocyte-like NADPH oxidase promotes cytokine-induced mitochondrial dysfunction in pancreatic-cells : evidence for regulation by Rac 1

A. Kowluru, Wasanthi Subasinghe, I. Syed, 2010 .

Differential regulation by fatty acids of protein histidine phosphorylation in rat pancreatic islets

A. Kowluru, 2004, Molecular and Cellular Biochemistry.

Alpha4 contributes to the dysfunction of the pancreatic beta cell under metabolic stress

A. Kowluru, B. Wadzinski, Mirabela Hali, 2022, Molecular and Cellular Endocrinology.

Quantitative proteomics reveals novel interaction partners of Rac1 in pancreatic β-cells: Evidence for increased interaction with Rac1 under hyperglycemic conditions

A. Kowluru, Z. Yi, X. Zhang, 2019, Molecular and Cellular Endocrinology.

Paradoxical regulation of glucose-induced Rac1 activation and insulin secretion by RhoGDIβ in pancreatic β-cells

A. Kowluru, V. Thamilselvan, 2019, Small GTPases.

Glucotoxicity promotes aberrant activation and mislocalization of Ras-related C3 botulinum toxin substrate 1 [Rac1] and metabolic dysfunction in pancreatic islet β-cells: reversal of such metabolic defects by metformin

A. Kowluru, D. L. Hynds, Anil Chekuri, 2017, Apoptosis.

Tiam1/Vav2‐Rac1 axis: A tug‐of‐war between islet function and dysfunction

A. Kowluru, 2017, Biochemical pharmacology.

A lack of ‘glue’ misplaces Rab27A to cause islet dysfunction in diabetes

A. Kowluru, 2016, The Journal of pathology.

Protein prenylation in islet β-cell function in health and diabetes: Putting the pieces of the puzzle together.

A. Kowluru, R. Kowluru, 2015, Biochemical pharmacology.

Further evidence for the regulation of acetyl-CoA carboxylase activity by a glutamate- and magnesium-activated protein phosphatase in the pancreatic beta cell: defective regulation in the diabetic GK rat islet.

A. Kowluru, R. Palanivel, R. Veluthakal, 2005, Endocrine.

Secretagogue-responsive and -unresponsive pools of phosphatidylinositol in pancreatic islets.

A. Kowluru, R. Rana, M. MacDonald, 1986, Archives of biochemistry and biophysics.

Rab-geranylgeranyl transferase regulates glucose-stimulated insulin secretion from pancreatic β cells

A. Kowluru, C. McKenna, D. Arora, 2012, Islets.

Activation of pancreatic islet myosin ATPase by ATP and actin.

A. Kowluru, M. MacDonald, C. Chang, 1985, Biochemical medicine.

Glucose-induced, calcium-mediated protein phosphorylation in intact pancreatic islets.

A. Kowluru, M. MacDonald, 1984, Archives of biochemistry and biophysics.

Phagocytic NADPH Oxidase Links ARNO-Arf6 Signaling Pathway in Glucose-Stimulated Insulin Secretion from the Pancreatic β-Cell

A. Kowluru, Bhavaani Jayaram, 2012, Cellular Physiology and Biochemistry.

GTP and Its Binding Proteins in the Regulation of Insulin Exocytosis

A. Kowluru, S. Metz, 1994 .

Protein farnesylation is requisite for mitochondrial fuel-induced insulin release

A. Kowluru, Chandrashekara N. Kyathanahalli, Andrea Matti, 2012, Islets.

Adenine and guanine nucleotide-specific succinyl-CoA synthetases in the clonal beta-cell mitochondria: implications in the beta-cell high-energy phosphate metabolism in relation to physiological insulin secretion

A. Kowluru, 2001, Diabetologia.

RhoG-Rac1 Signaling Pathway Mediates Metabolic Dysfunction of the Pancreatic Beta-Cells Under Chronic Hyperglycemic Conditions.

A. Kowluru, Mirabela Hali, Suhadinie Gamage, 2021, Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.

Underappreciated roles for Rho GDP Dissociation Inhibitors (RhoGDIs) in cell function: Lessons learned from the pancreatic islet β-cell.

A. Kowluru, N. Gleason, 2021, Biochemical pharmacology.

Protein histidine [de]phosphorylation in insulin secretion: abnormalities in models of impaired insulin secretion

A. Kowluru, J. Krieglstein, S. Klumpp, 2011, Naunyn-Schmiedeberg's Archives of Pharmacology.

Regulation of glucose- and mitochondrial fuel-induced insulin secretion by a cytosolic protein histidine phosphatase in pancreatic beta-cells.

L. Olson, A. Kowluru, J. Krieglstein, 2010, American journal of physiology. Endocrinology and metabolism.

Ceramide‐activated protein phosphatase‐2A activity in insulin‐secreting cells

A. Kowluru, S. Metz, 1997, FEBS letters.

Enzymes of phospholipid metabolism in rat pancreatic islets: Subcellular distribution and the effect of glucose and calcium

A. Kowluru, R. Rana, M. MacDonald, 1986, Journal of cellular biochemistry.

Depletion of the catalytic subunit of protein phosphatase-2A (PP2Ac) markedly attenuates glucose-stimulated insulin secretion in pancreatic β-cells

A. Kowluru, L. Susick, R. Veluthakal, 2007, Endocrine.

Defective protein histidine phosphorylation in islets from the Goto-Kakizaki diabetic rat.

A. Kowluru, 2003, American journal of physiology. Endocrinology and metabolism.

Evidence for phosphorylation of pancreatic islet pyruvate kinase.

A. Kowluru, M. MacDonald, C. Chang, 1985, Metabolism: clinical and experimental.

Protein phosphorylation in pancreatic islets: evidence for separate Ca2+ and cAMP-enhanced phosphorylation of two 57,000 Mr proteins.

A. Kowluru, M. MacDonald, 1984, Biochemical and biophysical research communications.

GTP-binding protein-independent potentiation by mastoparan of IL-1β-induced nitric oxide release from insulin-secreting HIT-T15 cells

A. Kowluru, R. Palanivel, R. Veluthakal, 2004, Apoptosis.

[20] Subcellular distribution and posttranslational modifications of GTP-binding proteins in insulin-secreting cells

A. Kowluru, S. Metz, 1996 .

Nm23-H1 Regulates Glucose-Stimulated Insulin Secretion in Pancreatic β-Cells via Arf6-Rac1 Signaling Axis

A. Kowluru, D. Kaetzel, R. Veluthakal, 2013, Cellular Physiology and Biochemistry.

Inhibition of Prenylation Promotes Caspase 3 Activation, Lamin B Degradation and Loss in Metabolic Cell Viability in Pancreatic β-Cells

A. Kowluru, K. Syeda, 2017, Cellular Physiology and Biochemistry.

Non-specific stimulatory effects of mastoparan on pancreatic islet nucleoside diphosphokinase activity: dissociation from insulin secretion.

M. Rabaglia, S. Seavey, A. Kowluru, 1995, Biochemical pharmacology.

Interleukin-1 beta induces posttranslational carboxymethylation and alterations in subnuclear distribution of lamin B in insulin-secreting RINm5F cells.

A. Kowluru, R. Amin, R. Veluthakal, 2004, American journal of physiology. Cell physiology.

CALL FOR PAPERS Protein and Vesicle Trafﬁcking, Cytoskeleton Interleukin-1 (cid:1) induces posttranslational carboxymethylation and alterations in subnuclear distribution of lamin B in insulin-secreting RINm5F cells

A. Kowluru, R. Amin, R. Veluthakal, 2004 .

Protein and Vesicle Trafficking , Cytoskeleton Interleukin-1 induces posttranslational carboxymethylation and alterations in subnuclear distribution of lamin B in insulin-secreting RINm 5 F cells

A. Kowluru, R. Amin, R. Veluthakal, 2004 .

Evidence for calcium enhanced phosphorylation of pyruvate kinase by pancreatic islets

A. Kowluru, M. MacDonald, 1985, Molecular and Cellular Biochemistry.

Phospholipid methyltransferase activity in pancreatic islets: activation by calcium.

A. Kowluru, R. Rana, M. MacDonald, 1985, Archives of biochemistry and biophysics.

Calcium-activated factors in pancreatic islets that inhibit actin polymerization.

A. Kowluru, M. MacDonald, 1982, Archives of biochemistry and biophysics.

Activation of apocynin-sensitive NADPH oxidase (Nox2) activity in INS-1 832/13 cells under glucotoxic conditions

A. Kowluru, Abiy M. Mohammed, 2013, Islets.

Nifedipine prevents etoposide-induced caspase-3 activation, prenyl transferase degradation and loss in cell viability in pancreatic β-cells

A. Kowluru, D. Arora, Abiy M. Mohammed, 2012, Apoptosis.

Phospholipid N‐methylation in diabetic erythrocytes: Effects on membrane Na+, K+ ATPase activity

A. Kowluru, R. Kowluru, 1992, Cell biochemistry and function.

Characterization of nucleoside diphosphokinase activity in human and rodent pancreatic beta cells: evidence for its role in the formation of guanosine triphosphate, a permissive factor for nutrient-induced insulin secretion.

A. Kowluru, S. Metz, 1994, Biochemistry.

Glycation of calmodulin: chemistry and structural and functional consequences.

N. W. Downer, T. W. Whaley, J. Trewhella, 1989, Biochemistry.

Emerging roles for protein histidine phosphorylation in cellular signal transduction: lessons from the islet β-cell

A. Kowluru, 2008, Journal of cellular and molecular medicine.

Hyperactivation of protein phosphatase 2A in models of glucolipotoxicity and diabetes: potential mechanisms and functional consequences.

A. Kowluru, Andrea Matti, 2012, Biochemical pharmacology.

Localization and characterization of the mitochondrial isoform of the nucleoside diphosphate kinase in the pancreatic beta cell: evidence for its complexation with mitochondrial succinyl-CoA synthetase.

A. Kowluru, M. Tannous, Hai-Qing Chen, 2002, Archives of biochemistry and biophysics.

Oxidative stress and epigenetic modifications in the pathogenesis of diabetic retinopathy

A. Kowluru, M. Mishra, R. Kowluru, 2015, Progress in Retinal and Eye Research.

A farnesylated G-protein suppresses Akt phosphorylation in INS 832/13 cells and normal rat islets: regulation by pertussis toxin and PGE₂.

A. Kowluru, C. Kyathanahalli, 2011, Biochemical pharmacology.

Reversible sodium pump defect and swelling in the diabetic rat erythrocyte: effects on filterability and implications for microangiopathy.

M. Dembo, A. Kowluru, M. Bitensky, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Metastasis suppressor NME1 regulates melanoma cell morphology, self‐adhesion and motility via induction of fibronectin expression

David M. Kaetzel, A. Kowluru, D. Kaetzel, 2015, Experimental dermatology.

Kinome profiling reveals abnormal activity of kinases in skeletal muscle from adults with obesity and insulin resistance.

S. Drăghici, R. Tagett, A. Kowluru, 2020, The Journal of clinical endocrinology and metabolism.

Epigenetics and Regulation of Oxidative Stress in Diabetic Retinopathy

A. Kowluru, M. Mishra, A. Duraisamy, 2018, Investigative ophthalmology & visual science.

COPII-Dependent ER Export: A Critical Component of Insulin Biogenesis and β-Cell ER Homeostasis.

B. Jena, A. Kowluru, Ming Liu, 2015, Molecular endocrinology.

Regulation by glucose and calcium of the carboxylmethylation of the catalytic subunit of protein phosphatase 2A in insulin-secreting INS-1 cells.

A. Kowluru, R. Palanivel, Anjaneyulu Kowluru, 2004, American journal of physiology. Endocrinology and metabolism.

Inosine monophosphate dehydrogenase: A molecular switch integrating pleiotropic GTP-dependent beta-cell functions.

A. Kowluru, S. Metz, 1999, Proceedings of the Association of American Physicians.

Roles of GTP and Rho GTPases in pancreatic islet beta cell function and dysfunction

A. Kowluru, 2020, Small GTPases.

Role of G‐proteins in islet function in health and diabetes

A. Kowluru, Anjaneyulu Kowluru, 2017, Diabetes, obesity & metabolism.

Metabolic Stress Induces Caspase-3 Mediated Degradation and Inactivation of Farnesyl and Geranylgeranyl Transferase Activities in Pancreatic β-Cells

A. Kowluru, M. Goalstone, R. Kowluru, 2016, Cellular Physiology and Biochemistry.

Regulatory roles for Tiam1, a guanine nucleotide exchange factor for Rac1, in glucose-stimulated insulin secretion in pancreatic beta-cells.

L. Olson, A. Kowluru, Anjaneyulu Kowluru, 2009, Biochemical pharmacology.

Oxidative Stress in Cytokine-Induced Dysfunction of the Pancreatic Beta Cell: Known Knowns and Known Unknowns

A. Kowluru, 2020, Metabolites.

Hyperlipidemia and the development of diabetic retinopathy: Comparison between type 1 and type 2 animal models.

A. Kowluru, M. Mishra, R. Kowluru, 2016, Metabolism: clinical and experimental.

Bridging the Gap Between Protein Carboxyl Methylation and Phospholipid Methylation to Understand Glucose-Stimulated Insulin Secretion From the Pancreatic β Cell

A. Kowluru, 2008 .

Functional Regulation of an Oxidative Stress Mediator, Rac1, in Diabetic Retinopathy

A. Kowluru, A. Duraisamy, R. Kowluru, 2019, Molecular Neurobiology.

J. Johnson, A. Kowluru, S. Solomon, 1987, The Journal of experimental medicine.

Evidence for differential roles of the Rho subfamily of GTP-binding proteins in glucose- and calcium-induced insulin secretion from pancreatic beta cells.

M. Rabaglia, A. Kowluru, K. Aktories, 1997, Biochemical pharmacology.

Novel Role of GPR35 (G-Protein–Coupled Receptor 35) in the Regulation of Endothelial Cell Function and Blood Pressure

A. Kowluru, Jiemei Wang, Wei Chen, 2021, Hypertension.

Lipotoxicity augments glucotoxicity-induced mitochondrial damage in the development of diabetic retinopathy.

A. Kowluru, R. Kowluru, Binit Kumar, 2015, Investigative ophthalmology & visual science.

Tiam1-Rac1 Axis Promotes Activation of p38 MAP Kinase in the Development of Diabetic Retinopathy: Evidence for a Requisite Role for Protein Palmitoylation

A. Kowluru, R. Kowluru, R. Veluthakal, 2015, Cellular Physiology and Biochemistry.

GTP-binding proteins in cell survival and demise: the emerging picture in the pancreatic beta-cell.

N. Morgan, A. Kowluru, 2002, Biochemical pharmacology.

Subcellular localization and kinetic characterization of guanine nucleotide binding proteins in normal rat and human pancreatic islets and transformed beta cells.

M. Rabaglia, A. Kowluru, S. Metz, 1994, Biochimica et biophysica acta.

Down-regulation of expression and function of nucleoside diphosphate kinase in insulin-secreting β-cells under in vitro conditions of glucolipotoxicity

M. V. Suresh, A. Kowluru, R. Veluthakal, 2009, Molecular and Cellular Biochemistry.

Quantitative proteomics reveals novel protein interaction partners of PP2A catalytic subunit in pancreatic β-cells

S. Drăghici, R. Tagett, A. Kowluru, 2016, Molecular and Cellular Endocrinology.

Ceramide induces mitochondrial abnormalities in insulin-secreting INS-1 cells: Potential mechanisms underlying ceramide-mediated metabolic dysfunction of the β cell

A. Kowluru, R. Palanivel, Y. Zhao, 2005, Apoptosis.

Glucose- and GTP-dependent stimulation of the carboxyl methylation of CDC42 in rodent and human pancreatic islets and pure beta cells. Evidence for an essential role of GTP-binding proteins in nutrient-induced insulin secretion.

M. Rabaglia, S. Seavey, A. Kowluru, 1996, The Journal of clinical investigation.

TIAM1–RAC1 signalling axis-mediated activation of NADPH oxidase-2 initiates mitochondrial damage in the development of diabetic retinopathy

A. Kowluru, M. Mishra, G. Mohammad, 2014, Diabetologia.

Preferential excretion of glycated albumin in C57BL-Ks-J mice: Effects of diabetes

A. Kowluru, R. Kowluru, 1992, Experientia.

siRNA-mediated depletion of endogenous protein phosphatase 2Acalpha markedly attenuates ceramide-activated protein phosphatase activity in insulin-secreting INS-832/13 cells.

A. Kowluru, R. Veluthakal, G. R. Jangati, 2006, Biochemical and biophysical research communications.

Metformin Increases Protein Phosphatase 2A Activity in Primary Human Skeletal Muscle Cells Derived from Lean Healthy Participants

A. Kowluru, B. Seyoum, Z. Yi, 2021, Journal of diabetes research.

Characterization of prenylcysteine methyltransferase in insulin-secreting cells.

A. Kowluru, S. Metz, G. Li, 1996, The Biochemical journal.

The Regulatory Role of Rac1, a Small Molecular Weight GTPase, in the Development of Diabetic Retinopathy

A. Kowluru, N. Sahajpal, R. Kowluru, 2019, Journal of clinical medicine.

Phagocyte-like NADPH oxidase (Nox2) promotes activation of p38MAPK in pancreatic β-cells under glucotoxic conditions: Evidence for a requisite role of Ras-related C3 botulinum toxin substrate 1 (Rac1).

P. Newsholme, Vaibhav Sidarala, A. Kowluru, 2015, Biochemical pharmacology.

Novel regulatory roles for protein phosphatase-2A in the islet beta cell.

A. Kowluru, 2005, Biochemical pharmacology.

Novel roles for palmitoylation of Ras in IL-1 beta-induced nitric oxide release and caspase 3 activation in insulin-secreting beta cells.

A. Kowluru, M. Tannous, R. Amin, 2003, Biochemical pharmacology.

Multiple Guanine Nucleotide Exchange Factors Mediate Glucose-Induced Rac1 Activation and Insulin Secretion: Is It Precise Regulatory Control or a Case of Two Peas from the Same Pod?

A. Kowluru, 2021, ACS pharmacology & translational science.

EHT 1864, a small molecule inhibitor of Ras-related C3 botulinum toxin substrate 1 (Rac1), attenuates glucose-stimulated insulin secretion in pancreatic β-cells.

Vaibhav Sidarala, A. Kowluru, R. Veluthakal, 2015, Cellular signalling.

Regulatory roles for nm23/nucleoside diphosphate kinase-like enzymes in insulin secretion from the pancreatic islet beta cell

A. Kowluru, D. Kaetzel, R. Veluthakal, 2006, Journal of bioenergetics and biomembranes.

Inhibitors of post-translational modifications of G-proteins as probes to study the pancreatic beta cell function: potential therapeutic implications.

A. Kowluru, R. Amin, 2002, Current drug targets. Immune, endocrine and metabolic disorders.

Identification and characterization of a novel protein histidine kinase in the islet β cell: evidence for its regulation by mastoparan, an activator of G-proteins and insulin secretion

A. Kowluru, 2002 .

Stimulation by prostaglandin E2 of a high-affinity GTPase in the secretory granules of normal rat and human pancreatic islets.

A. Kowluru, S. Metz, 1994, The Biochemical journal.

Identification and characterization of a novel protein histidine kinase in the islet beta cell: evidence for its regulation by mastoparan, an activator of G-proteins and insulin secretion.

A. Kowluru, 2002, Biochemical pharmacology.

A novel regulatory mechanism for trimeric GTP-binding proteins in the membrane and secretory granule fractions of human and rodent beta cells.

S. Seavey, A. Kowluru, C. Rhodes, 1996, The Biochemical journal.

IL-1beta-induced nitric oxide release from insulin-secreting beta-cells: further evidence for the involvement of GTP-binding proteins.

A. Kowluru, M. Tannous, R. Amin, 2002, Diabetes & metabolism.

Inhibition of GPR39 restores defects in endothelial cell–mediated neovascularization under the duress of chronic hyperglycemia: Evidence for regulatory roles of the sonic hedgehog signaling axis

A. Kowluru, Jiemei Wang, Liping Xu, 2022, Proceedings of the National Academy of Sciences of the United States of America.

A. Kowluru, D. L. Hynds, Anil Chekuri, 2017, Apoptosis.

Erythrocyte sodium-potassium ATPase activity and thiol metabolism in genetically hyperglycemic mice.

A. Kowluru, R. Kowluru, 1992, Metabolism: clinical and experimental.

Nonenzymatic Glycosylation of Erythrocyte Cytoskeletal Proteins in Diabetes Mellitus1

A. Kowluru, M. Bitensky, R. Kowluru, 1987 .

Glucotoxic and diabetic conditions induce caspase 6-mediated degradation of nuclear lamin A in human islets, rodent islets and INS-1 832/13 cells

Vaibhav Sidarala, A. Kowluru, Syeda Khadija, 2014, Apoptosis.

Stimulation of phospholipid methylation by glucose in pancreatic islets.

A. Kowluru, R. Rana, M. MacDonald, 1984, Biochemical and biophysical research communications.

The two faces of protein palmitoylation in islet β-cell function: potential implications in the pathophysiology of islet metabolic dysregulation and diabetes.

A. Kowluru, Fei Chen, Abiy M. Mohammed, 2013, Recent patents on endocrine, metabolic & immune drug discovery.

Phagocyte-like NADPH oxidase promotes cytokine-induced mitochondrial dysfunction in pancreatic β-cells: evidence for regulation by Rac1.

A. Kowluru, Wasanthi Subasinghe, I. Syed, 2011, American journal of physiology. Regulatory, integrative and comparative physiology.

Oxidative stress and epigenetic modifications in the pathogenesis of diabetic retinopathy

A. Kowluru, R. Kowluru, Binit Kumar, 2015, Progress in Retinal and Eye Research.

Reversible sodium pump defect and swelling in the diabetic rat erythrocyte: effects on filterability and implications for microangiopathy.

A. Kowluru, M. Bitensky, T. Buican, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Regulatory Roles of Histone Deacetylation in Metabolic Stress-Induced Expression of Caspase Recruitment Domain-Containing Protein 9 (CARD9) in Pancreatic β-Cells

A. Kowluru, Mirabela Hali, N. Gleason, 2023, International journal of molecular sciences.