I. Tews

发表

Specificity determinants of recruitment peptides bound to phospho-CDK2/cyclin A.

Ivo Tews, Sheraz Gul, Martin E M Noble, 2002, Biochemistry.

Crystal structure of a bacterial chitinase at 2.3 A resolution.

K S Wilson, Z Dauter, A Perrakis, 1994, Structure.

Agonistic CD27 antibody potency is determined by epitope-dependent receptor clustering augmented through Fc-engineering

M. Cragg, I. Tews, T. Keler, 2022, Communications Biology.

Isotype Switching Converts Anti-CD40 Antagonism to Agonism to Elicit Potent Antitumor Activity

M. Cragg, I. Tews, M. Glennie, 2020, Cancer cell.

PLP-dependent enzymes as potential drug targets for protozoan diseases.

I. Tews, B. Kappes, P. Macheroux, 2011, Biochimica et biophysica acta.

The molecular chaperone Hsp90 delivers precursor proteins to the chloroplast import receptor Toc64

I. Tews, T. Becker, E. Schleiff, 2006, The EMBO journal.

Cholesteryl esters stabilize human CD1c conformations for recognition by self-reactive T cells

T. Elliott, J. Essex, B. Jakobsen, 2016, Proceedings of the National Academy of Sciences.

Measuring energy-dependent photoelectron escape in microcrystals

Selina L. S. Storm, I. Tews, G. Evans, 2020, IUCrJ.

Pyridoxal Phosphate Biosynthesis

I. Tews, T. Begley, S. Ealick, 2010 .

Defining the structural requirements for ribose 5‐phosphate‐binding and intersubunit cross‐talk of the malarial pyridoxal 5‐phosphate synthase

W. Lehmann, K. Rippe, I. Tews, 2010, FEBS letters.

Extensive substrate recognition by the streptococcal antibody-degrading enzymes IdeS and EndoS

I. Tews, M. Crispin, Abigail S L Sudol, 2022, bioRxiv.

Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility

J. Essex, M. Cragg, I. Tews, 2022, Science Immunology.

Characterization of two putative Dichelobacter nodosus footrot vaccine antigens identifies the first lysozyme inhibitor in the genus

I. Tews, M. V. Humbert, M. Christodoulides, 2019, Scientific reports.

The GTPase cycle of the chloroplast import receptors Toc33/Toc34: implications from monomeric and dimeric structures.

K. Rippe, I. Tews, I. Sinning, 2008, Structure.

On-Site Analysis of Bacterial Communities of the Ultraoligotrophic South Pacific Gyre

R. Amann, B. Fuchs, F. Glöckner, 2019, Applied and Environmental Microbiology.

Structure‐Function Studies on the Chitinolytic Enzymes of Serratia marcescens Chitinase and Chitobiase

I. Tews, C. Vorgias, A. Perrakis, 1996, Annals of the New York Academy of Sciences.

Substrate binding disrupts dimerization and induces nucleotide exchange of the chloroplast GTPase Toc33.

I. Tews, I. Sinning, E. Schleiff, 2011, The Biochemical journal.

Policing Tic 'n' Toc, the doorway to chloroplasts.

I. Tews, E. Schleiff, M. Oreb, 2008, Trends in cell biology.

Fatty acid regulation of adenylyl cyclase Rv2212 from Mycobacterium tuberculosis H37Rv

I. Tews, A. Motaal, J. Schultz, 2006, The FEBS journal.

Serial Femtosecond Zero Dose Crystallography Captures a Water‐Free Distal Heme Site in a Dye‐Decolorising Peroxidase to Reveal a Catalytic Role for an Arginine in FeIV=O Formation

H. Sugimoto, A. Ebrahim, Michael T. Wilson, 2020, Angewandte Chemie.

Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases

R. Strange, I. Tews, A. Wagner, 2017, Scientific Reports.

Extensive substrate recognition by the streptococcal antibody-degrading enzymes IdeS and EndoS

I. Tews, M. Crispin, Abigail S L Sudol, 2022, bioRxiv.

Cholesteryl esters stabilise human CD1c conformations for recognition by self-reactive T cells

Rajendra, Schumann, T. Elliott, 2015 .

The N-terminal cysteine pair of yeast sulfhydryl oxidase Erv1p is essential for in vivo activity and interacts with the primary redox centre.

I. Tews, G. Hofhaus, T. Lisowsky, 2003, European journal of biochemistry.

Fixed Target Serial Data Collection at Diamond Light Source.

Selina L. S. Storm, A. Ebrahim, I. Tews, 2021, Journal of visualized experiments : JoVE.

Dissection of contributions from invariant amino acids to complex formation and catalysis in the heteromeric pyridoxal 5-phosphate synthase complex from Bacillus subtilis.

I. Tews, P. Macheroux, S. Wallner, 2009, Biochemistry.

N-Acetylglucosaminidase (chitobiase) from Serratia marcescens: gene sequence, and protein production and purification in Escherichia coli.

R. Vincentelli, I. Tews, C. Vorgias, 1996, Gene.

Functional Analysis of PDX2 from Arabidopsis, a Glutaminase Involved in Vitamin B6 Biosynthesis1[W][OA]

I. Tews, N. Amrhein, T. Fitzpatrick, 2007, Plant Physiology.

Impact of a plastid-bearing endocytobiont on apicomplexan genomes.

R. Wilson, I. Tews, S. Sato, 2000, International journal for parasitology.

pH sensitivity of the GTPase Toc33 as a regulatory circuit for protein translocation into chloroplasts.

I. Tews, E. Schleiff, P. Koenig, 2008, Plant & cell physiology.

Cell surface counter receptors are essential components of the unconventional export machinery of galectin-1

M. Künzler, M. Aebi, W. Nickel, 2005, The Journal of cell biology.

Bacterial chitobiase structure provides insight into catalytic mechanism and the basis of Tay–Sachs disease

Zbigniew Dauter, Keith S. Wilson, Anastassis Perrakis, 1996, Nature Structural Biology.

CD1b-restricted GEM T cell responses are modulated by Mycobacterium tuberculosis mycolic acid meromycolate chains

T. Elliott, J. Essex, B. Marshall, 2017, Proceedings of the National Academy of Sciences.

Phylogenetic Analysis with Prediction of Cofactor or Ligand Binding for Pseudomonas aeruginosa PAS and Cache Domains

I. Tews, M. Walsh, J. Webb, 2021, Microbiology spectrum.

Vitamin Biosynthetic Pathways, the PLP Synthase Complex, and the Potential for Targeting Protein–Protein Interaction

I. Tews, I. Sinning, 2011 .

A Direct Role for Phosphatidylinositol‐4,5‐bisphosphate in Unconventional Secretion of Fibroblast Growth Factor 2

W. Nickel, I. Tews, I. Sinning, 2008, Traffic.

Successful sample preparation for serial crystallography experiments

A. Ebrahim, S. Carr, I. Tews, 2019, Journal of applied crystallography.

Conserved Properties of Polypeptide Transport-associated (POTRA) Domains Derived from Cyanobacterial Omp85*

I. Tews, I. Sinning, E. Schleiff, 2010, The Journal of Biological Chemistry.

Pyridoxal phosphate: biosynthesis and catabolism.

I. Tews, T. Begley, S. Ealick, 2011, Biochimica et biophysica acta.

Two independent routes of de novo vitamin B6 biosynthesis: not that different after all.

I. Tews, B. Kappes, P. Macheroux, 2007, The Biochemical journal.

LILRB3 (ILT5) is a myeloid cell checkpoint that elicits profound immunomodulation

Des C. Jones, J. Trowsdale, Jianzhu Chen, 2020, JCI insight.

LILRB3 (ILT5) is a myeloid checkpoint on myeloid cells that elicits profound immununomodulation

Des C. Jones, J. Trowsdale, Jianzhu Chen, 2020, bioRxiv.

Activation of the myeloid checkpoint inhibitor LILRB3 (ILT5) elicits profound immununomodulation

Des C. Jones, J. Trowsdale, Jianzhu Chen, 2020 .

The Structure of a pH-Sensing Mycobacterial Adenylyl Cyclase Holoenzyme

F. Findeisen, I. Tews, I. Sinning, 2005, Science.

OX40: Structure and function - What questions remain?

M. Cragg, I. Tews, J. Willoughby, 2017, Molecular immunology.

Substrate-Assisted Catalysis Unifies Two Families of Chitinolytic Enzymes

Keith S. Wilson, Anastassis Perrakis, Ivo Tews, 1997 .

Structure and Conservation of the Periplasmic Targeting Factor Tic22 Protein from Plants and Cyanobacteria*

I. Tews, I. Sinning, E. Schleiff, 2012, The Journal of Biological Chemistry.

Structural and functional characterization of IdiA/FutA (Tery_3377), an iron-binding protein from the ocean diazotroph Trichodesmium erythraeum

I. Tews, A. Baylay, T. Bibby, 2018, The Journal of Biological Chemistry.

Structural Basis for a Distinct Catalytic Mechanism in Trypanosoma brucei Tryparedoxin Peroxidase*

I. Tews, I. Sinning, R. Krauth-Siegel, 2008, Journal of Biological Chemistry.

Complex Interplay between Epitope Specificity and Isotype Dictates the Biological Activity of Anti-human CD40 Antibodies

M. Cragg, I. Tews, M. Glennie, 2018, Cancer cell.

Mdm38 is a 14‐3‐3‐Like Receptor and Associates with the Protein Synthesis Machinery at the Inner Mitochondrial Membrane

D. Lupo, I. Tews, P. Rehling, 2011, Traffic.

Structure of the Recombinant Neisseria gonorrhoeae Adhesin Complex Protein (rNg-ACP) and Generation of Murine Antibodies with Bactericidal Activity against Gonococci

I. Tews, M. V. Humbert, M. Christodoulides, 2018, mSphere.

Structure and Regulation of EAL Domain Proteins

I. Tews, M. Walsh, J. Webb, 2020 .

Crystallization of recombinant chitobiase from Serratia marcescens.

Z. Dauter, A. Oppenheim, I. Tews, 1992, Journal of molecular biology.

On the Significance of Toc-GTPase Homodimers*

K. Rippe, I. Tews, I. Sinning, 2008, Journal of Biological Chemistry.

Characterization of two putative Dichelobacter nodosus footrot vaccine antigens identifies the first lysozyme inhibitor in the genus

I. Tews, M. V. Humbert, M. Christodoulides, 2019, Scientific reports.

Solubilization of aggregated proteins by ClpB/DnaK relies on the continuous extraction of unfolded polypeptides

B. Bukau, I. Tews, A. Mogk, 2004, FEBS letters.

Differential impact on motility and biofilm dispersal of closely related phosphodiesterases in Pseudomonas aeruginosa

I. Tews, M. Walsh, J. Webb, 2019, Scientific Reports.

Reducing affinity as a strategy to boost immunomodulatory antibody agonism

J. Essex, M. Cragg, I. Tews, 2023, Nature.

Towards a better understanding of human iNKT cell subpopulations for improved clinical outcomes

I. Tews, A. Roghanian, Daniel Burns, 2023, Frontiers in Immunology.

Techno-economic analysis of corn stover fungal fermentation to ethanol

Susanne B. Jones, Iva J. Tews, Pimphan A. Meyer, 2013 .

Structural and thermodynamic insights into the assembly of the heteromeric pyridoxal phosphate synthase from Plasmodium falciparum.

I. Tews, B. Kappes, P. Macheroux, 2007, Journal of molecular biology.

X‐ray crystal structure of Saccharomyces cerevisiae Pdx1 provides insights into the oligomeric nature of PLP synthases

K. Rippe, I. Tews, I. Sinning, 2009, FEBS letters.

Structure of a bacterial pyridoxal 5′-phosphate synthase complex

Ivo Tews, Karsten Rippe, Thomas Raschle, 2006, Proceedings of the National Academy of Sciences.

The structure of the regulatory domain of the adenylyl cyclase Rv1264 from Mycobacterium tuberculosis with bound oleic acid.

F. Wieland, F. Findeisen, I. Tews, 2007, Journal of molecular biology.

Nitrogen-doped char as a catalyst for wet oxidation of phenol-contaminated water

I. Tews, M. García-Pérez, Jean-Sabin McEwen, 2021 .

Evaluating Anti-CD32b F(ab) Conformation Using Molecular Dynamics and Small-Angle X-Ray Scattering

Richard T. Bradshaw, J. Essex, M. Cragg, 2018, Biophysical journal.

Low-Severity Hydroprocessing to Stabilize Bio-oil: TechnoEconomic Assessment

Douglas C. Elliott, Iva J. Tews, D. Elliott, 2014 .

Vitamin B6 Biosynthesis by the Malaria Parasite Plasmodium falciparum

S. Müller, I. Tews, I. Sinning, 2006, Journal of Biological Chemistry.

A redox switch allows binding of Fe(II) and Fe(III) ions in the cyanobacterial iron binding protein FutA from Prochlorococcus

G. Murshudov, I. Tews, J. Worrall, 2023, bioRxiv.

Formation and dimerization of the phosphodiesterase active site of the Pseudomonas aeruginosa MorA, a bi‐functional c‐di‐GMP regulator

I. Tews, C. Keevil, H. Mikolajek, 2014, FEBS letters.

Biomass Direct Liquefaction Options. TechnoEconomic and Life Cycle Assessment

Kristin Onarheim, Yrjö Solantausta, Douglas C. Elliott, 2014 .

Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis.

G. Guédez, I. Tews, I. Sinning, 2017, Nature chemical biology.

The CCP4 suite: integrative software for macromolecular crystallography

Soon Wen Hoh, Stuart J McNicholas, P. Emsley, 2023, Acta crystallographica. Section D, Structural biology.

Thermodynamic characterization of the protein-protein interaction in the heteromeric Bacillus subtilis pyridoxalphosphate synthase.

Ivo Tews, Marco Strohmeier, I. Tews, 2007, Biochemistry.

Functional Analysis of PDX 2 from Arabidopsis , a Glutaminase Involved in Vitamin B 6 Biosynthesis 1 [ W ] [ OA ]

I. Tews, N. Amrhein, T. Fitzpatrick, 2007 .

Bespoke conformation and antibody recognition distinguishes the streptococcal immune evasion factors EndoS and EndoS2

I. Tews, M. Crispin, Abigail S. L. Sudol, 2023, bioRxiv.

Cell surface counter receptors are essential components of the unconventional export machinery of galectin-1

M. Künzler, M. Aebi, W. Nickel, 2005, The Journal of cell biology.

Structure and Conservation of the Periplasmic Targeting Factor Tic22 Protein from Plants and Cyanobacteria*

I. Tews, I. Sinning, E. Schleiff, 2012, The Journal of Biological Chemistry.