P. Legault

发表

Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53.

Toshiaki Hara, Pascale Legault, Ettore Appella, 2006, Molecular cell.

Methods for Measurement of Intermolecular NOEs by Multinuclear NMR Spectroscopy: Application to a Bacteriophage λ N-Peptide/boxB RNA Complex

Jack Greenblatt, Pascale Legault, Lewis E. Kay, 1997 .

Solution structure of bovine neutrophil beta-defensin-12: the peptide fold of the beta-defensins is identical to that of the classical defensins.

A. Pardi, G. Zimmermann, M. Selsted, 1995, Biochemistry.

Preparation of λN-GST fusion protein for affinity immobilization of RNA.

J. Omichinski, P. Legault, Geneviève Di Tomasso, 2012, Methods in molecular biology.

Structural characterization of interactions between transactivation domain 1 of the p65 subunit of NF-κB and transcription regulatory factors

J. Omichinski, P. Legault, Geneviève Arseneault, 2017, Nucleic acids research.

NMR structure of the A730 loop of the Neurospora VS ribozyme: insights into the formation of the active site

J. Boisbouvier, P. Legault, Nicolas Girard, 2011, Nucleic acids research.

VGluT2 Expression in Dopamine Neurons Contributes to Postlesional Striatal Reinnervation

Christian Rosenmund, L. Trudeau, P. Legault, 2020, The Journal of Neuroscience.

TDP-43 stabilizes G3BP1 mRNA: relevance to amyotrophic lateral sclerosis/frontotemporal dementia

L. Zinman, P. Legault, M. Tétreault, 2021, Brain : a journal of neurology.

TDP-43 stabilizes transcripts encoding stress granule protein G3BP1: potential relevance to ALS/FTD

L. Zinman, P. Legault, M. Tétreault, 2020, bioRxiv.

In situ Probing of Adenine Protonation in RNA by 13C NMR

A. Pardi, P. Legault, 1994 .

Structural variation induced by different nucleotides at the cleavage site of the hammerhead ribozyme.

O. Uhlenbeck, A. Pardi, J. Simorre, 1998, Biochemistry.

Letter to the Editor: 1H, 15N, and 13C Resonance Assignment of the 23 kDa Organomercurial Lyase MerB in its Free and Mercury-bound Forms

J. Omichinski, P. Legault, G. Benison, 2004, Journal of biomolecular NMR.

NMR structural studies reveal a novel protein fold for MerB, the organomercurial lyase involved in the bacterial mercury resistance system.

J. Omichinski, P. Di Lello, P. Legault, 2004, Biochemistry.

NMR structure of the active conformation of the Varkud satellite ribozyme cleavage site

P. Gendron, F. Major, P. Legault, 2003, Proceedings of the National Academy of Sciences of the United States of America.

A stable mercury-containing complex of the organomercurial lyase MerB: catalysis, product release, and direct transfer to MerA.

J. Omichinski, P. Di Lello, P. Legault, 2004, Biochemistry.

A multi-axial RNA joint with a large range of motion promotes sampling of an active ribozyme conformation

P. Legault, Nicolas Girard, P. Dagenais, 2019, Nucleic acids research.

NMR solution structure of the lead-dependent ribozyme: evidence for dynamics in RNA catalysis.

A. Pardi, P. Legault, A Pardi, 1998, Journal of Molecular Biology.

Structure of a (Cys3His) zinc ribbon, a ubiquitous motif in archaeal and eucaryal transcription

J. Omichinski, P. Legault, R. A. Scott, 2000, Protein science : a publication of the Protein Society.

Insights into RNA structure and dynamics from recent NMR and X‐ray studies of the Neurospora Varkud satellite ribozyme

P. Legault, Nicolas Girard, P. Dagenais, 2017, Wiley interdisciplinary reviews. RNA.

The NMR structure of the II–III–VI three-way junction from the Neurospora VS ribozyme reveals a critical tertiary interaction and provides new insights into the global ribozyme structure

Sébastien Lemieux, Nicolas Girard, Pascale Legault, 2015, RNA.

NMR Localization of Divalent Cations at the Active Site of the Neurospora VS Ribozyme Provides Insights into RNA–Metal-Ion Interactions

P. Legault, É. Bonneau, 2013, Biochemistry.

Preparation of 13C and 15N labelled RNAs for heteronuclear multi-dimensional NMR studies.

A. Pardi, E. Nikonowicz, F. Jucker, 1992, Nucleic acids research.

Improved measurement of 13C, 31P J coupling constants in isotopically labeled RNA

A. Pardi, F. Jucker, P. Legault, 1995, FEBS letters.

Stepwise assembly of multiple Lin28 proteins on the terminal loop of let-7 miRNA precursors

P. Legault, J. Bouvette, A. Desjardins, 2014, Nucleic acids research.

ARiBo pull-down for riboproteomic studies based on label-free quantitative mass spectrometry

P. Legault, Geneviève Di Tomasso, L. M. Miller Jenkins, 2016, RNA.

Importance of the NCp7-like domain in the recognition of pre-let-7g by the pluripotency factor Lin28

J. Omichinski, P. Legault, Ao Yang, 2011, Nucleic acids research.

Importance of the NCp 7-like domain in the recognition of pre-let-7 g by the pluripotency factor Lin 28

J. Omichinski, P. Legault, Ao Yang, 2012 .

Affinity purification of T7 RNA transcripts with homogeneous ends using ARiBo and CRISPR tags

P. Legault, Geneviève Di Tomasso, Alix Salvail-Lacoste, 2013, RNA.

High-yield production of human Dicer by transfection of human HEK293-EBNA1 cells grown in suspension

J. Omichinski, P. Legault, Y. Durocher, 2018, BMC Biotechnology.

Structural characterization of a noncovalent complex between ubiquitin and the transactivation domain of the erythroid-specific factor EKLF.

J. Omichinski, P. Legault, M. Lussier-Price, 2013, Structure.

Structure-based design of a potent artificial transactivation domain based on p53.

J. Omichinski, P. Legault, M. Lussier-Price, 2012, Journal of the American Chemical Society.

Structural and functional evidence that Rad4 competes with Rad2 for binding to the Tfb1 subunit of TFIIH in NER

J. Omichinski, P. Legault, Geneviève Arseneault, 2013, Nucleic acids research.

Structure and mechanism in transcriptional antitermination by the bacteriophage lambda N protein.

J. Greenblatt, L. Kay, P. Legault, 1998, Cold Spring Harbor symposia on quantitative biology.

Independent ligand-induced folding of the RNA-binding domain and two functionally distinct antitermination regions in the phage lambda N protein.

Joyce Li, J. Greenblatt, L. Kay, 1998, Molecular cell.

A conformational change in the catalytic core of the hammerhead ribozyme upon cleavage of an RNA substrate.

A. Pardi, J. Simorre, P. Legault, 1997, Biochemistry.

Biomolecular NMR Spectroscopy of Ribonucleic Acids

P. Legault, T. Dieckmann, M. Piazza, 2014 .

Order, dynamics and metal-binding in the lead-dependent ribozyme.

A. Pardi, P. Legault, C. G. Hoogstraten, 1998, Journal of molecular biology.

Studies on the mechanism of inactivation of the HIV-1 nucleocapsid protein NCp7 with 2-mercaptobenzamide thioesters.

S. Stahl, E. Appella, J. Omichinski, 2005, Journal of medicinal chemistry.

Riboswitch structure: an internal residue mimicking the purine ligand

Patricia Bouchard, Daniel A. Lafontaine, Pascale Legault, 2009, Nucleic acids research.

Interactions of the HIV-1 Tat and RAP74 proteins with the RNA polymerase II CTD phosphatase FCP1.

J. Greenblatt, R. Roeder, J. Omichinski, 2005, Biochemistry.

Affinity purification of RNA using an ARiBo tag.

P. Legault, V. Delfosse, P. Dagenais, 2012, Methods in molecular biology.

Structural and functional characterization of interactions involving the Tfb1 subunit of TFIIH and the NER factor Rad2

J. Omichinski, P. Legault, Geneviève Arseneault, 2012, Nucleic acids research.

p53 and TFIIEα share a common binding site on the Tfb1/p62 subunit of TFIIH

J. Omichinski, P. Di Lello, P. Legault, 2008, Proceedings of the National Academy of Sciences.

NMR structure of a complex containing the TFIIF subunit RAP74 and the RNA polymerase II carboxyl-terminal domain phosphatase FCP1

J. Greenblatt, M. Kobor, J. Omichinski, 2003, Proceedings of the National Academy of Sciences of the United States of America.

NMR structure of the complex between the Tfb1 subunit of TFIIH and the activation domain of VP16: structural similarities between VP16 and p53.

J. Omichinski, L. Jenkins, P. Di Lello, 2008, Journal of the American Chemical Society.

Nuclear magnetic resonance structure of the III-IV-V three-way junction from the Varkud satellite ribozyme and identification of magnesium-binding sites using paramagnetic relaxation enhancement.

P. Legault, É. Bonneau, 2014, Biochemistry.

Enhanced binding of RNAP II CTD phosphatase FCP1 to RAP74 following CK2 phosphorylation.

M. J. Chalmers, J. Omichinski, B. D. Nguyen, 2005, Biochemistry.

NMR Structure of the Bacteriophage λ N Peptide/boxB RNA Complex: Recognition of a GNRA Fold by an Arginine-Rich Motif

Jack Greenblatt, Pascale Legault, Joyce Li, 1998, Cell.

Affinity purification of in vitro transcribed RNA with homogeneous ends using a 3'-ARiBo tag.

J. Omichinski, P. Legault, Geneviève Di Tomasso, 2014, Methods in enzymology.

NMR structure of the amino-terminal domain from the Tfb1 subunit of TFIIH and characterization of its phosphoinositide and VP16 binding sites.

M. Kobor, J. Omichinski, P. Di Lello, 2005, Biochemistry.

A remarkably stable kissing-loop interaction defines substrate recognition by the Neurospora Varkud Satellite ribozyme

P. Legault, P. Bouchard, 2014, RNA.

The ARiBo tag: a reliable tool for affinity purification of RNAs under native conditions

J. Omichinski, P. Legault, P. Dagenais, 2010, Nucleic acids research.

An integrative NMR-SAXS approach for structural determination of large RNAs defines the substrate-free state of a trans-cleaving Neurospora Varkud Satellite ribozyme

P. Legault, P. Dagenais, Geneviève Desjardins, 2021, Nucleic acids research.

Role of SLV in SLI substrate recognition by the Neurospora VS ribozyme.

F. Major, S. Lemieux, P. Legault, 2008, RNA.

p53 and TFIIEalpha share a common binding site on the Tfb1/p62 subunit of TFIIH.

J. Omichinski, P. Di Lello, P. Legault, 2008, Proceedings of the National Academy of Sciences of the United States of America.

Letter to the Editor: 1H, 15N, and 13C resonance assignment of the amino-terminal domain of the Tfb1 subunit of yeast TFIIH

J. Omichinski, B. D. Nguyen, P. Legault, 2005, Journal of biomolecular NMR.

Unusual dynamics and pKa shift at the active site of a lead dependent ribozyme

A. Pardi, P. Legault, 1997 .

Helix-length compensation studies reveal the adaptability of the VS ribozyme architecture

S. Lemieux, P. Legault, Nicolas Girard, 2011, Nucleic acids research.

Constitutive Regulatory Activity of an Evolutionarily Excluded Riboswitch Variant*

Pascale Legault, Paul Dupont, D. Lafontaine, 2011, The Journal of Biological Chemistry.

Through-bond correlation of adenine protons in a 13C-labeled ribozyme

L. Mueller, B. Farmer, A. Pardi, 1994 .

Improved RNA Structure Determination by Detection of NOE Contacts to Exchange-Broadened Amino Protons

L. Mueller, A. Pardi, P. Legault, 1995 .

Mutations at the guanosine-binding site of the Tetrahymena ribozyme also affect site-specific hydrolysis.

T. Cech, D. Herschlag, P. Legault, 1992, Nucleic acids research.

Engineering of the Neurospora Varkud Satellite Ribozyme for Cleavage of Nonnatural Stem‐Loop Substrates

P. Legault, Nicolas Girard, P. Dagenais, 2021, Ribozymes.

Structural Insights Into Substrate Recognition by the Neurospora Varkud Satellite Ribozyme: Importance of U-Turns at the Kissing-Loop Junction

P. Legault, P. Bouchard, 2013, Biochemistry.

Rational engineering of the Neurospora VS ribozyme to allow substrate recognition via different kissing-loop interactions

P. Legault, Nicolas Girard, P. Dagenais, 2016, Nucleic acids research.

Multivalent binding oligomers inhibit HIV Tat-TAR interaction critical for viral replication.

R. Ptak, K. Jeang, P. Legault, 2009, Bioorganic & medicinal chemistry letters.

Solution structure of the carboxyl-terminal domain of RAP74 and NMR characterization of the FCP1-binding sites of RAP74 and human TFIIB.

J. Greenblatt, M. Kobor, J. Omichinski, 2003, Biochemistry.

Nuclear magnetic resonance structure of the Varkud satellite ribozyme stem-loop V RNA and magnesium-ion binding from chemical-shift mapping.

P. Legault, D. Campbell, 2005, Biochemistry.

Comparison of the specificity of interaction of cellular and viral zinc-binding domains with 2-mercaptobenzamide thioesters.

S. Stahl, S. Durell, E. Appella, 2006, Journal of the American Chemical Society.

Functional and structural characterization of a dense core secretory granule sorting domain from the PC1/3 protease

R. Ghirlando, J. Omichinski, P. Di Lello, 2009, Proceedings of the National Academy of Sciences.

Structure-based design of a potent artificial transactivation domain based on p53.

J. Omichinski, P. Legault, M. Lussier-Price, 2012, Journal of the American Chemical Society.

Riboswitch structure: an internal residue mimicking the purine ligand

D. Lafontaine, P. Legault, V. Delfosse, 2009, Nucleic acids research.

NMR structure of a complex formed by the carboxyl-terminal domain of human RAP74 and a phosphorylated peptide from the central domain of the FCP1 phosphatase.

J. Omichinski, P. Di Lello, P. Legault, 2009, Biochemistry.