S. Qiu

发表

Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2-p53 interaction.

Su Qiu, Guoping Wang, Wei Gao, 2006, Journal of medicinal chemistry.

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

Dajun Yang, Su Qiu, Guoping Wang, 2008, Proceedings of the National Academy of Sciences.

Structure-based design of potent small-molecule inhibitors of anti-apoptotic Bcl-2 proteins.

H. Abaan, Shaomeng Wang, Renxiao Wang, 2006, Journal of medicinal chemistry.

Structure-based design of flavonoid compounds as a new class of small-molecule inhibitors of the anti-apoptotic Bcl-2 proteins.

Shaomeng Wang, Renxiao Wang, Chao-yie Yang, 2007, Journal of medicinal chemistry.

Acylpyrogallols as inhibitors of antiapoptotic Bcl-2 proteins.

Shaomeng Wang, Chao-yie Yang, Z. Nikolovska-Coleska, 2008, Journal of medicinal chemistry.

Structure-based design of potent non-peptide MDM2 inhibitors.

J. Deschamps, Shaomeng Wang, Yipin Lu, 2005, Journal of the American Chemical Society.

Molecular basis of inhibitory peptide maurotoxin recognizing Kv1.2 channel explored by ZDOCK and molecular dynamic simulations

Su Qiu, Yingliang Wu, Wenxin Li, 2008, Proteins.

SM-164: a novel, bivalent Smac mimetic that induces apoptosis and tumor regression by concurrent removal of the blockade of cIAP-1/2 and XIAP.

Shaomeng Wang, Yi Sun, Z. Nikolovska-Coleska, 2008, Cancer research.

Discovery of a novel nonphosphorylated pentapeptide motif displaying high affinity for Grb2-SH2 domain by the utilization of 3'-substituted tyrosine derivatives.

Megan L. Peach, Shaomeng Wang, S. Qiu, 2006, Journal of medicinal chemistry.

Structure-Function Analysis of Severe Acute Respiratory Syndrome Coronavirus RNA Cap Guanine-N7-Methyltransferase

Ying Sun, T. Ahola, S. Qiu, 2013, Journal of Virology.

Therapeutic Potential and Molecular Mechanism of a Novel, Potent, Nonpeptide, Smac Mimetic SM-164 in Combination with TRAIL for Cancer Treatment

Shaomeng Wang, Shi-Yong Sun, S. Qiu, 2011, Molecular Cancer Therapeutics.

SdPI, The First Functionally Characterized Kunitz-Type Trypsin Inhibitor from Scorpion Venom

S. Qiu, Z. Cao, Yingliang Wu, 2011, PloS one.

Cyclopeptide Smac mimetics as antagonists of IAP proteins.

Liu Liu, Shaomeng Wang, Chao-yie Yang, 2010, Bioorganic & medicinal chemistry letters.

Design, synthesis, and evaluation of potent, nonpeptidic mimetics of second mitochondria-derived activator of caspases.

Shaomeng Wang, Chao-yie Yang, Z. Nikolovska-Coleska, 2009, Journal of medicinal chemistry.

Potent bivalent Smac mimetics: effect of the linker on binding to inhibitor of apoptosis proteins (IAPs) and anticancer activity.

Liu Liu, Shaomeng Wang, Chao-yie Yang, 2011, Journal of medicinal chemistry.

Design of Small‐Molecule Peptidic and Nonpeptidic Smac Mimetics

Shaomeng Wang, Chao-yie Yang, Z. Nikolovska-Coleska, 2009 .

Design, synthesis, and evaluation of tricyclic, conformationally constrained small-molecule mimetics of second mitochondria-derived activator of caspases.

Shaomeng Wang, Chao-yie Yang, Z. Nikolovska-Coleska, 2008, Journal of medicinal chemistry.

Potent and orally active small-molecule inhibitors of the MDM2-p53 interaction.

Shanghai Yu, Dajun Yang, Su Qiu, 2009, Journal of medicinal chemistry.

A potent and orally active antagonist (SM-406/AT-406) of multiple inhibitor of apoptosis proteins (IAPs) in clinical development for cancer treatment.

Tao Zhang, Dajun Yang, Su Qiu, 2011, Journal of medicinal chemistry.

Potent, orally bioavailable diazabicyclic small-molecule mimetics of second mitochondria-derived activator of caspases.

Dajun Yang, Su Qiu, Han Yi, 2008, Journal of medicinal chemistry.

Discovery of a nanomolar inhibitor of the human murine double minute 2 (MDM2)-p53 interaction through an integrated, virtual database screening strategy.

Xueliang Fang, Su Qiu, Xueliang Fang, 2006, Journal of medicinal chemistry.

An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid

S. Foster, T. Mak, M. Hashimoto, 2003, Nature Immunology.

Design, synthesis, and characterization of a potent, nonpeptide, cell-permeable, bivalent Smac mimetic that concurrently targets both the BIR2 and BIR3 domains in XIAP.

Sheng Jiang, Yumi Ueda, Su Qiu, 2007, Journal of the American Chemical Society.

Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo

S. Varambally, A. Chinnaiyan, S. Foster, 2006, The Journal of experimental medicine.

to stimulate chemokine production and neutrophil recruitment in vivo

S. Varambally, A. Chinnaiyan, S. Foster, 2006 .

Reactivation of p53 by a specific MDM2 antagonist (MI-43) leads to p21-mediated cell cycle arrest and selective cell death in colon cancer

Shaomeng Wang, Yipin Lu, T. Carey, 2008, Molecular Cancer Therapeutics.

Nonpeptidic and potent small-molecule inhibitors of cIAP-1/2 and XIAP proteins.

Su Qiu, Han Yi, Liu Liu, 2010, Journal of medicinal chemistry.

Structure-based design, synthesis, evaluation, and crystallographic studies of conformationally constrained Smac mimetics as inhibitors of the X-linked inhibitor of apoptosis protein (XIAP).

Su Qiu, Jianfeng Lu, Chao-Yie Yang, 2008, Journal of medicinal chemistry.

Design of small-molecule peptidic and nonpeptidic Smac mimetics.

Su Qiu, Jianfeng Lu, Shaomeng Wang, 2008, Accounts of chemical research.

Interaction of a cyclic, bivalent smac mimetic with the x-linked inhibitor of apoptosis protein.

Shaomeng Wang, Z. Nikolovska-Coleska, S. Qiu, 2008, Biochemistry.

Design, synthesis, and characterization of new embelin derivatives as potent inhibitors of X-linked inhibitor of apoptosis protein.

Shaomeng Wang, Z. Nikolovska-Coleska, Guoping Wang, 2006, Bioorganic & medicinal chemistry letters.

Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition

M. Chamaillard, G. Tromp, S. Qiu, 2004, The EMBO journal.

RNA Cap Guanine-N7-Methyltransferase Acute Respiratory Syndrome Coronavirus Structure-Function Analysis of Severe

T. Ahola, S. Qiu, Yingliang Wu, 2014 .

The binding mode of fusion inhibitor T20 onto HIV-1 gp41 and relevant T20-resistant mechanisms explored by computational study.

S. Qiu, Yingliang Wu, Hong Yi, 2012, Current HIV research.

Design, synthesis, and evaluation of a potent, cell-permeable, conformationally constrained second mitochondria derived activator of caspase (Smac) mimetic.

Shaomeng Wang, W. Gao, Z. Nikolovska-Coleska, 2006, Journal of medicinal chemistry.

Protein-protein recognition control by modulating electrostatic interactions.

Su Qiu, Yingliang Wu, S. Qiu, 2010, Journal of proteome research.

Pyrogallol-based molecules as potent inhibitors of the antiapoptotic Bcl-2 proteins.

Sheng Jiang, Renxiao Wang, Su Qiu, 2007, Journal of medicinal chemistry.

Differential molecular information of maurotoxin peptide recognizing IKCa and Kv1.2 channels explored by computational simulation

S. Qiu, Baoshan Wang, Yingliang Wu, 2011, BMC Structural Biology.

The molecular recognition mechanism for superoxide dismutase presequence binding to the mitochondrial protein import receptor Tom20 from Oryza sativa involves an LRTLA motif.

Marc Baaden, Su Qiu, Yingliang Wu, 2010, The journal of physical chemistry. B.

Acylpyrogallols as inhibitors of antiapoptotic Bcl-2 proteins.

Shaomeng Wang, Z. Nikolovska-Coleska, S. Qiu, 2008, Journal of medicinal chemistry.

Discovery of a nanomolar inhibitor of the human murine double minute 2 (MDM2)-p53 interaction through an integrated, virtual database screening strategy.

Xueliang Fang, Su Qiu, Xueliang Fang, 2006, Journal of medicinal chemistry.

Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo

S. Varambally, A. Chinnaiyan, S. Foster, 2006, The Journal of experimental medicine.

Molecular Information of Charybdotoxin Blockade in the Large Conductance Calcium-activated Potassium Channel

Hong Yi, Su Qiu, Hui Liu, 2009, J. Chem. Inf. Model..

Design, Synthesis and Characterization of New Embelin Derivatives as Potent Inhibitors of X-Linked Inhibitor of Apoptosis Protein.

Shaomeng Wang, Z. Nikolovska-Coleska, Guoping Wang, 2007 .