P. Roller

发表

Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2-p53 interaction.

Su Qiu, Guoping Wang, Wei Gao, 2006, Journal of medicinal chemistry.

P. Roller, C. Fox, F. B. Johnson, 1985, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

The central region of Gadd45 is required for its interaction with p21/WAF1.

A. Fornace, Q. Zhan, S. Jin, 2000, Experimental cell research.

Structure-based design of potent small-molecule inhibitors of anti-apoptotic Bcl-2 proteins.

H. Abaan, Shaomeng Wang, Renxiao Wang, 2006, Journal of medicinal chemistry.

Structure-based design of flavonoid compounds as a new class of small-molecule inhibitors of the anti-apoptotic Bcl-2 proteins.

Shaomeng Wang, Renxiao Wang, Chao-yie Yang, 2007, Journal of medicinal chemistry.

Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening.

I. Enyedy, Y. Tomita, P. Roller, 2001, Journal of medicinal chemistry.

Haloforms in the essential oil of the alga asparagopsis taxiformis (rhodophyta)

Richard E. Moore, P. Roller, B. Burreson, 1975 .

Volatile halogen compounds in the alga Asparagopsis taxiformis (Rhodophyta)

Richard E. Moore, P. Roller, B. Burreson, 1976 .

Halogenated acetamides, but-3-en-2-ols, and isopropanols from asparagopsis taxiformis (delile) trev

Richard E. Moore, P. Roller, F. Woolard, 1976 .

Halogenated acetic and acrylic acids from the red alga Asparagopsis taxiformis

Richard E. Moore, P. Roller, F. Woolard, 1979 .

Structure-based design of potent non-peptide MDM2 inhibitors.

J. Deschamps, Shaomeng Wang, Yipin Lu, 2005, Journal of the American Chemical Society.

Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database.

Dajun Yang, Xueliang Fang, Renxiao Wang, 2004 .

Development and optimization of a binding assay for the XIAP BIR3 domain using fluorescence polarization.

Xueliang Fang, Renxiao Wang, Shaomeng Wang, 2004, Analytical biochemistry.

A p21(Waf1/Cip1)carboxyl-terminal peptide exhibited cyclin-dependent kinase-inhibitory activity and cytotoxicity when introduced into human cells.

R. Sikorski, P. O'Connor, M. Mutoh, 1999, Cancer research.

Synthesis and HIV-1 integrase inhibitory activity of dimeric and tetrameric analogs of indolicidin.

Y. Pommier, K. Krajewski, P. Roller, 2004, Bioorganic & medicinal chemistry letters.

Isolation and structure elucidation of a novel griseorhodin.

P. Roller, J. Chan, R. Stroshane, 1979, The Journal of antibiotics.

Structure-based design, synthesis, and evaluation of conformationally constrained mimetics of the second mitochondria-derived activator of caspase that target the X-linked inhibitor of apoptosis protein/caspase-9 interaction site.

Shaomeng Wang, Chao-yie Yang, Y. Tomita, 2004, Journal of medicinal chemistry.

Structure-Based Design, Synthesis and Biochemical Testing of Novel and Potent Smac Peptido-Mimetics.

Shaomeng Wang, Chao-yie Yang, Y. Tomita, 2005 .

Direct N‐terminal sequence analysis of rat liver plasma membrane glycoproteins separated by two‐dimensional polyacrylamide gel electrophoresis

S. Thorgeirsson, D. Parmelee, P. Roller, 1989, Electrophoresis.

Mutagenicity and in vitro covalent DNA binding of 2-hydroxyamino-3-methylimidazolo[4,5-f]quinoline.

S. Thorgeirsson, R. Adamson, P. Roller, 1988, Carcinogenesis.

Reaction of N-hydroxylamine and N-acetoxy derivatives of 2-amino-3-methylimidazolo[4,5-f]quinoline with DNA. Synthesis and identification of N-(deoxyguanosin-8-yl)-IQ.

S. Thorgeirsson, R. Adamson, P. Roller, 1988, Carcinogenesis.

Enzymatic conversion of benzo(a)pyrene leading predominantly to the diol-epoxide r-7,t-8-dihydroxy-t-9,10-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene through a single enantiomer of r-7, t-8-dihydroxy-7,8-dihydrobenzo(a)pyrene.

P. Roller, H. Gelboin, D. McCourt, 1976, Proceedings of the National Academy of Sciences of the United States of America.

Potent inhibition of insulin receptor dephosphorylation by a hexamer peptide containing the phosphotyrosyl mimetic F2Pmp.

P. Roller, T. Burke, H. Kole, 1994, Biochemical and biophysical research communications.

Significant compensatory role of position Y-2 conferring high affinity to non-phosphorylated inhibitors of Grb2-SH2 domain.

P. Roller, J. Voigt, F. Lung, 1999, Bioorganic & medicinal chemistry letters.

Functional preference of the constituent amino acid residues in a phage-library-based nonphosphorylated inhibitor of the Grb2-SH2 domain.

P. Roller, F. Lung, X. Wu, 2001, The journal of peptide research : official journal of the American Peptide Society.

Structural basis for a non-phosphorus-containing cyclic peptide binding to Grb2-SH2 domain with high affinity.

Dajun Yang, P. Roller, P. Li, 2003, Biochemical and biophysical research communications.

Structure-based design of potent Grb2-SH2 domain antagonists not relying on phosphotyrosine mimics.

P. Roller, R. Fisher, P. Li, 2006, Biochemical and biophysical research communications.

Discovery of a novel nonphosphorylated pentapeptide motif displaying high affinity for Grb2-SH2 domain by the utilization of 3'-substituted tyrosine derivatives.

Shaomeng Wang, S. Qiu, P. Roller, 2006, Journal of medicinal chemistry.

Covalent binding of the natural antimicrobial peptide indolicidin to DNA abasic sites

Y. Pommier, K. Krajewski, P. Roller, 2006, Nucleic acids research.

Oligomerization of Human Gadd45a Protein*

A. Fornace, P. Roller, F. Lung, 2001, The Journal of Biological Chemistry.

Design and synthesis of paclitaxel conjugated with an ErbB2-recognizing peptide, EC-1.

D. Krag, P. Roller, P. Li, 2007, Biopolymers.

Structure of fredericamycin A, an antitumor antibiotic of a novel skeletal type; spectroscopic and mass spectral characterization.

R. C. Pandey, P. Roller, B. Hilton, 1987, The Journal of antibiotics.

Glycosylation affects both the three-dimensional structure and antibody binding properties of the HIV-1IIIB GP120 peptide RP135.

P. Roller, F. Lung, X. Huang, 1997, Biochemistry.

A Specific Sequence of the Laminin 2 Chain Critical for the Initiation of Heterotrimer Assembly (*)

A. Utani, P. Roller, M. Nomizu, 1995, The Journal of Biological Chemistry.

Carcinogenic effect of dinitrosopiperazine in adult Swiss mice and after transplacental or translactational exposure.

P. Roller, L. Nádasdi, A. Surján, 1980, Cancer research.

Syp (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction.

S. Shoelson, J. Olefsky, P. Roller, 1994, The Journal of biological chemistry.

Stereoselectivity in the microsomal conversion of N-nitrosodimethylamine to formaldehyde.

P. Roller, J. Saavedra, L. Keefer, 1990, Chemical research in toxicology.

Identification of Novel Non-phosphorylated Ligands, Which Bind Selectively to the SH2 Domain of Grb7*

D. Krag, P. Roller, R. Daly, 2002, The Journal of Biological Chemistry.

Evidence for a 2,3-epoxide as an intermediate in the microsomal metabolism of benzo[a]pyrene to 3-hydroxybenzo[a]pyrene.

P. Roller, P. Fu, R. Harvey, 1977, Biochemical and biophysical research communications.

Enzymatic mechanism of benzo[a]pyrene conversion to phenols and diols and an improved high-pressure liquid chromatographic separation of benzo[a]pyrene derivatives.

P. Roller, H. Gelboin, S. K. Yang, 1977, Biochemistry.

Conversion of proteins to diazeniumdiolate-based nitric oxide donors.

P. Roller, J. Saavedra, L. Keefer, 1999, Bioconjugate chemistry.

Hydrolysis of iodine labelled urodilatin and ANP by recombinant neutral endopeptidase EC. 3.4.24.11

P. Roller, E. Golomb, Z. Abassi, 1994, British journal of pharmacology.

Design and characterization of bivalent Smac-based peptides as antagonists of XIAP and development and validation of a fluorescence polarization assay for XIAP containing both BIR2 and BIR3 domains.

Shaomeng Wang, Z. Nikolovska-Coleska, Wei-Lin Gao, 2008, Analytical biochemistry.

Synthesis and conformation of the trimeric coiled-coil segment of laminin.

A. Utani, P. Roller, Y. Yamada, 2009, International journal of peptide and protein research.

Isolation and identification of 4-hydroxy- and 4-oxoretinoic acid. In vitro metabolites of all-trans-retinoic acid in hamster trachea and liver.

M. Sporn, D. Newton, P. Roller, 1979, Biochemistry.

d‐Val22 containing human big endothelin‐1 analog, [d‐Val22]Big ET‐1[16–38], inhibits the endothelin converting enzyme

P. Roller, M. Nomizu, H. Yokogoshi, 1994, FEBS letters.

Two-step hard acid deprotection/cleavage procedure for solid phase peptide synthesis.

P. Roller, A. Otaka, M. Nomizu, 2009, International journal of peptide and protein research.

Solid phase peptide synthesis of human endothelin precursor peptides using two-step hard acid deprotection/cleavage methods.

P. Roller, A. Iwamatsu, A. Otaka, 2009, International journal of peptide and protein research.

The stereochemistry of hydrogen addition by a delta1-steroid reductase in baker's yeast.

P. Roller, A. W. Nicholas, O. R. Rodig, 1974, Biochemical and biophysical research communications.

Structural requirements for Tyr in the consensus sequence Y-E-N of a novel nonphosphorylated inhibitor to the Grb2-SH2 domain.

P. Roller, T. Burke, Z. Yao, 1999, Biochemical and biophysical research communications.

Functional site studies with peptide segments of Cdk inhibitory proteins

P. O'Connor, M. Mutoh, P. Roller, 2002 .

Structure-based design of potent, conformationally constrained Smac mimetics.

Shaomeng Wang, Chao-yie Yang, Y. Tomita, 2004, Journal of the American Chemical Society.

The all-D-configuration segment containing the IKVAV sequence of laminin A chain has similar activities to the all-L-peptide in vitro and in vivo.

A. Utani, P. Roller, Y. Yamada, 1992, The Journal of biological chemistry.

Structure-based design, synthesis and biochemical testing of novel and potent Smac peptido-mimetics.

Shaomeng Wang, Chao-yie Yang, Y. Tomita, 2005, Bioorganic & medicinal chemistry letters.

Development of l-3-aminotyrosine suitably protected for the synthesis of a novel nonphosphorylated hexapeptide with low-nanomolar Grb2-SH2 domain-binding affinity.

P. Roller, Y. Long, Yan-li Song, 2004, Bioorganic & medicinal chemistry letters.

Novel peptide inhibitors for Grb2 SH2 domain and their detection by surface plasmon resonance.

P. Roller, F. Lung, J. Tsai, 2002, The journal of peptide research : official journal of the American Peptide Society.

32P-postlabeling analysis of IQ, MeIQx and PhIP adducts formed in vitro in DNA and polynucleotides and found in vivo in hepatic DNA from IQ-, MeIQx- and PhIP-treated monkeys.

C. Davis, P. Roller, E. Snyderwine, 1993, Carcinogenesis.

SYNTHESIS AND SOLVOLYSIS OF METHYL(ACETOXYMETHYL)NITROSAMINE, SOLUTION CHEMISTRY OF THE PRESUMED CARCINOGENIC METABOLITE OF DIMETHYLNITROSAMINE

P. Roller, L. Keefer, Dale R. Shimp, 1975 .

Physico-chemical and microbiological comparison of nystatin, amphotericin A and amphotericin B, and structure of amphotericin A.

A. Bax, P. Roller, C. McNeal, 1985, The Journal of antibiotics.

Microbial reduction of the side-chain carbonyl of daunorubicin and N-acetyldaunorubicin.

L. H. Wright, P. Roller, N. Bachur, 1977, The Journal of antibiotics.

Recent Progress of Synthetic Studies to Peptide and Peptidomimetic Cyclization

P. Roller, Zheng Li, K. Ding, 2008 .

Synthesis and application of N-Boc-L-2-amino-4-(diethylphosphono)-4,4-difluorobutanoic acid for solid-phase synthesis of nonhydrolyzable phosphoserine peptide analogues

P. Roller, T. Burke, A. Otaka, 1995 .

Discovery of thioether-bridged cyclic pentapeptides binding to Grb2-SH2 domain with high affinity.

P. Roller, R. Fisher, T. Burke, 2009, Bioorganic & medicinal chemistry letters.

MECHANISM OF MICROSOMAL ACTIVATION OF BENZO[a] PYRENE TO DIOL-EPOXIDES: THE SEPARATION AND CHARACTERIZATION OF INTERMEDIATES AND PRODUCTS

P. Roller, H. Gelboin, Shen K. Yang, 1977 .

Conformation of the second disulfide loop in human transforming growth factor‐α studied by two‐dimensional nmr spectroscopy

J. Ferretti, P. Roller, C. Niu, 1988, Biopolymers.

Structures of human TGFα fragments using two-dimensional proton magnetic resonance spectroscopy and computer simulation

B. Brooks, J. Ferretti, Kyou-Hoon Han, 1988 .

Synthesis of 4-phosphono(difluoromethyl)-D,L-phenylalanine and N-boc and N-Fmoc derivatives suitably protected for solid-phase synthesis of nonhydrolyzable phosphotyrosyl peptide analogues

P. Roller, A. Otaka, T. Burke, 1993 .

Structure and synthesis of tetrasubstituted pyrazines in ants in the genus mesoponera

David L. Williams, M. Blum, P. Roller, 1988 .

Design and synthesis of redox stable analogues of sunflower trypsin inhibitors (SFTI-1) on solid support, potent inhibitors of matriptase.

R. Dickson, P. Roller, P. Li, 2007, Organic letters.

Nonhydrolyzable phosphotyrosyl mimetics for the preparation of phosphatase-resistant SH2 domain inhibitors.

S. Shoelson, P. Roller, T. Burke, 1994, Biochemistry.

Protein-Tyrosine Phosphatase Inhibition by a Peptide Containing the Phosphotyrosyl Mimetic, L-O-Malonyltyrosine (L-OMT)

D. Barford, M. Akamatsu, P. Roller, 1995 .

The chemical identification of the rice weevil and maize weevil aggregation pheromone

J. K. Phillips, P. Roller, H. Fales, 1984 .

The metabolism of 6-aminochrysene in the rat.

P. Roller, E. Weisburger, P. H. Grantham, 1976, European journal of cancer.

Dajun Yang, Xueliang Fang, Renxiao Wang, 2004, Journal of medicinal chemistry.

Potent inhibition of protein-tyrosine phosphatase-1B using the phosphotyrosyl mimetic fluoro-O-malonyl tyrosine (FOMT).

L. Wu, P. Roller, T. Burke, 1998, Bioorganic & medicinal chemistry letters.

Potent inhibition of protein-tyrosine phosphatase by phosphotyrosine-mimic containing cyclic peptides.

M. Akamatsu, P. Roller, T. Burke, 1997, Bioorganic & medicinal chemistry.

Why is phosphonodifluoromethyl phenylalanine a more potent inhibitory moiety than phosphonomethyl phenylalanine toward protein-tyrosine phosphatases?

L. Wu, P. Roller, J. den Hertog, 1995, Biochemical and biophysical research communications.

Nonphosphorylated Peptide Ligands for the Grb2 Src Homology 2 Domain*

D. Krag, Shaomeng Wang, P. Roller, 1997, The Journal of Biological Chemistry.

A Helical Epitope in the C4 Domain of HIV Glycoprotein 120 (*)

P. Roller, M. Robert-Guroff, F. Robey, 1995, The Journal of Biological Chemistry.

A practical synthesis of fully protected l-γ-carboxyglutamic acid

P. Roller, C. Lai, Sheng Jiang, 2006 .

Alkaloid studies—LVIII

C. Djerassi, P. Roller, F. Gilbert, 1967 .

High-pressure liquid chromatographic analysis of benzo(alpha)pyrene metabolism and covalent binding and the mechanism of action of 7,8-benzoflavone and 1,2-epoxy-3,3,3-trichloropropane.

J. Selkirk, P. Roller, H. Gelboin, 1974, Cancer research.

Proteins in a Nonvenomous Defensive Secretion: Biosynthetic Significance

J. R. Aldrich, M. Blum, P. Roller, 1978, Science.

Isolation of S-(3-oxoundecyl) thioacetate, bis-(3-oxoundecyl) disulphide, (–)-3-hexyl-4,5-dithiacycloheptanone, and S-(trans-3-oxoundec-4-enyl) thioacetate from Dictyopteris

Richard E. Moore, P. Roller, K. Au, 1971 .

Chemical and biological studies on 5,6-epoxyretinol, retinol, and their phosphoryl esters.

P. Roller, L. D. De Luca, P. V. Bhat, 1981, Journal of lipid research.

Correlation of DNA methylation by methyl(acetoxymethyl)nitrosamine with organ-specific carcinogenicity in rats.

P. Kleihues, P. Roller, L. Keefer, 1979, Cancer research.

Inhibition of transforming growth factor-induced cell growth in soft agar by oxidized polyamines.

M. Sporn, P. Roller, J. Cone, 1984, Archives of biochemistry and biophysics.

Formation of DNA adducts from N-acetoxy-2-acetylaminofluorene and N-hydroxy-2-acetylaminofluorene in rat hemopoietic tissues in vivo.

S. Thorgeirsson, P. Roller, P. Wirth, 1986, Cancer research.

Cyclization strategies in peptide derived drug design.

P. Roller, P. Li, Peng Li, 2002, Current topics in medicinal chemistry.

Dose-dependent kinetics of all-trans-retinoic acid in rats. Plasma levels and excretion into bile, urine, and faeces.

D W Zaharevitz, M. Sporn, D. Zaharevitz, 1981, Biochemical pharmacology.

Tritium gas exposure as an alternative to base-catalyzed exchange for the one-step tritiation of nitrosamines

Winifred G. Palmer, P. Roller, L. Keefer, 1978 .

Intestinal tumors induced by a single intraperitoneal injection of methyl(acetoxymethyl)nitrosamine in three strains of rats.

J. Berman, P. Roller, J. Rice, 1979, Cancer research.

Natural history of intestinal neoplasms induced in rats by a single injection of methyl(acetoxymethyl)nitrosamine.

J. Ward, P. Roller, J. Rice, 1977, Cancer research.

Synthesis and solvolysis of methyl(acetoxymethyl)nitrosamine. Solution chemistry of the presumed carcinogenic metabolite ofdimethylnitrosamine

P. Roller, L. Keefer, Dale R. Shimp, 1975 .

Synthesis, analysis, and stability studies of 14C-methyl(acetoxymethyl)nitrosamine

P. Roller, L. Keefer, E. J. Reist, 1981 .

Dependence of tumor spectrum on route of administration in Sprague-Dawley rats as a result of single or multiple injections of methyl(acetoxymethyl)nitrosamine.

J. Berman, P. Roller, J. Rice, 1979, Journal of the National Cancer Institute.

Selective induction of intestinal tumors in rats by methyl(acetoxymethyl)nitrosamine, an ester of the presumed reactive metabolite of dimethylnitrosamine.

P. Roller, L. Keefer, J. Rice, 1977, Journal of the National Cancer Institute.

Structural studies and two-dimensional gel electrophoresis of γ-glutamyl transpeptidase

P. Roller, P. Wirth, I. Glowinski, 1986 .

Design and synthesis of dimeric HIV-1 integrase inhibitory peptides.

Y. Pommier, K. Krajewski, P. Roller, 2003, Bioorganic & medicinal chemistry letters.

Benzo(a)pyrene-7,8-dihydrodiol 9,10-oxide adenosine and deoxyadenosine adducts: structure and stereochemistry.

K. Nakanishi, I. Weinstein, P. Roller, 1979, Science.

Effect of Dimerization and Tetramerization on the Potency of HIV-1 Integrase Inhibitory Peptides

Y. Pommier, K. Krajewski, P. Roller, 2006 .

Stereochemistry of the hydrolysis products and their acetonides of two stereoisomeric benzo[a]pyrene 7,8-diol 9,10-epoxides.

P. Roller, H. Gelboin, D. McCourt, 1977, Journal of the American Chemical Society.

Metabolism of the dyestuff intermediate 2,4-diaminoanisole in the rat.

P. Roller, E. Weisburger, J. Miller, 1979, Xenobiotica; the fate of foreign compounds in biological systems.

Design, synthesis, and characterization of a potent, nonpeptide, cell-permeable, bivalent Smac mimetic that concurrently targets both the BIR2 and BIR3 domains in XIAP.

Sheng Jiang, Yumi Ueda, Su Qiu, 2007, Journal of the American Chemical Society.

The analysis of 2-acetamido-2-deoxyaldose derivatives by gas-liquid chromatography and mass spectrometry.

P. Roller, T. Orme, C. Boone, 1974, Carbohydrate research.

Detection of gilvocarcin antitumor complex by a biochemical induction assay (BIA).

P. Roller, R. White, J. Chan, 1982, The Journal of antibiotics.

The GADD45 Inhibition of Cdc2 Kinase Correlates with GADD45-mediated Growth Suppression*

A. Fornace, Q. Zhan, Shun-qian Jin, 2000, The Journal of Biological Chemistry.

Interaction of a cyclic, bivalent smac mimetic with the x-linked inhibitor of apoptosis protein.

Shaomeng Wang, Z. Nikolovska-Coleska, S. Qiu, 2008, Biochemistry.

Conformational transitions, dissociation, and unfolding of scrapie amyloid (prion) protein.

P. Roller, D. Gajdusek, C. Gibbs, 1993, The Journal of biological chemistry.

A Conformational Rearrangement upon Binding of IgE to Its High Affinity Receptor*

J. Kinet, S. Sechi, P. Roller, 1996, The Journal of Biological Chemistry.

Comparison of the conformation and GTP hydrolysing ability of N-terminal ras p21 protein segments.

K. Han, P. Roller, C. Niu, 1989, Biochemical and biophysical research communications.

A dual-readout F2 assay that combines fluorescence resonance energy transfer and fluorescence polarization for monitoring bimolecular interactions.

R. Dingledine, H. Fu, Shaomeng Wang, 2011, Assay and drug development technologies.

F(Pmp)-TAM, a Novel Competitive Inhibitor of the Binding of ZAP-70 to the T Cell Antigen Receptor, Blocks Early T Cell Signaling (*)

R. Aebersold, J. Watts, P. Roller, 1995, The Journal of Biological Chemistry.

Stability and peptide binding specificity of Btk SH2 domain: Molecular basis for X‐linked agammaglobulinemia

Benfang Lei, S. Tzeng, P. Roller, 2000, Protein science : a publication of the Protein Society.

Guanethidine N-oxide formation as a measure of cellular flavin-containing monooxygenase activity.

S. Thorgeirsson, P. Roller, M. McManus, 1983, Biochemical and biophysical research communications.

Thermal stability and conformational transitions of scrapie amyloid (prion) protein correlate with infectivity

P. Roller, D. Gajdusek, J. Safar, 1993, Protein science : a publication of the Protein Society.

Molecular mechanism of gossypol-induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells.

Dajun Yang, Manchao Zhang, Shaomeng Wang, 2003, Biochemical pharmacology.

Design and synthesis of novel and potent inhibitors of the type II transmembrane serine protease, matriptase, based upon the sunflower trypsin inhibitor-1.

R. Dickson, P. Roller, Michael D. Johnson, 2007, Journal of medicinal chemistry.

Development of non-phosphorylated cyclic thioether peptide binding to the Grb2-SH2 domain

P. Roller, F. Lung, C. King, 2006, Letters in Peptide Science.

A Synthetic Conformational Epitope from the C4 Domain of HIV Gp120 That Binds CD4*

P. Roller, M. Robert-Guroff, B. Ivanov, 1996, The Journal of Biological Chemistry.

Rabbit beta-globin is extended beyond its UGA stop codon by multiple suppressions and translational reading gaps.

William Arbuthnot Sir Lane, B. Carlson, D. Hatfield, 1998, Biochemistry.

Scrapie amyloid (prion) protein has the conformational characteristics of an aggregated molten globule folding intermediate.

P. Roller, D. Gajdusek, C. Gibbs, 1994, Biochemistry.

N-Nitrosation by Nitrite Ion in Neutral and Basic Medium

P. Roller, Larry K. Keeper, 1973, Science.

Characterization of p21Cip1/Waf1 peptide domains required for cyclin E/Cdk2 and PCNA interaction.

P. O'Connor, A. Fornace, M. L. Smith, 1996, Oncogene.

Structural basis for inhibition of the protein tyrosine phosphatase 1B by phosphotyrosine peptide mimetics.

T R Burke, D. Barford, P. Roller, 1998, Biochemistry.

Cyclic peptide inhibitors of phosphatidylinositol 3-kinase p85 SH2 domain binding.

S. Shoelson, P. Roller, T. Burke, 1994, Biochemical and biophysical research communications.

Concise and enantioselective synthesis of Fmoc-Pmp(But)2-OH and design of potent Pmp-containing Grb2-SH2 domain antagonists.

Dajun Yang, P. Roller, Manchao Zhang, 2003, Organic letters.

Chemical synthesis and applications of phosphopeptides.

K. Sakaguchi, E. Appella, P. Roller, 1996, Genetic engineering.

Synthesis and structure activity studies of phosphatase resistant SH2 domain inhibiting peptides: D-amino acid effects

S. Shoelson, P. Roller, T. Burke, 1995 .

Synthesis and structure-activity studies of SH2 binding peptides containing hydrolytically stable analogs of O -phosphotyrosine

S. Shoelson, P. Roller, T. Burke, 1994 .

Use of 3,4-dichlorobenzenethiol as a trapping agent for alkylating intermediates during in vitro metabolism of nitrosamines.

P. Roller, L. Keefer, C. Michejda, 1985, Cancer research.

Synthesis and evaluation of the sunflower derived trypsin inhibitor as a potent inhibitor of the type II transmembrane serine protease, matriptase.

I. Enyedy, P. Roller, Y. Long, 2001, Bioorganic & medicinal chemistry letters.

Calorimetric investigation of phosphorylated and non‐phosphorylated peptide ligand binding to the human Grb7‐SH2 domain

D. Krag, P. Roller, A. Spuches, 2007, Journal of molecular recognition : JMR.

Conformational analysis of cyclic hexapeptides designed as constrained ligands for the SH2 domain of the p85 subunit of phosphatidylinositol-3-OH kinase.

P. Roller, T. Burke, A. Otaka, 1996, Biopolymers.

Norleucine as a replacement for methionine in phosphatase-resistant linear and cyclic peptides which bind to p85 SH2 domains

S. Shoelson, P. Roller, T. Burke, 1994 .

Laminin chain assembly. Specific sequences at the C terminus of the long arm are required for the formation of specific double- and triple-stranded coiled-coil structures.

R. Timpl, A. Utani, P. Roller, 1994, Journal of Biological Chemistry.

Enzymic N-acetylation of 2,4-toluenediamine by liver cytosols from various species.

P. Roller, T. Glinsukon, E. Weisburger, 1975, Xenobiotica; the fate of foreign compounds in biological systems.

Design and synthesis of a new, conformationally constrained, macrocyclic small-molecule inhibitor of STAT3 via 'click chemistry'.

Shaomeng Wang, Z. Nikolovska-Coleska, Wei-Lin Gao, 2007, Bioorganic & medicinal chemistry letters.

Potential proximate carcinogens of 7,12-dimethylbenz[a]anthracene: characterization of two metabolically formed trans-3,4-dihydrodiols

P. Roller, M. Chou, Shen K. Yang, 1979 .

Relationship between 7,12-dimethyl- and 7,8,12-trimethylbenz[a]anthracene DNA adduct formation in hematopoietic organs and leukemogenic effects.

S. Thorgeirsson, P. Roller, M. Falzon, 1987, Cancer letters.

Solution structure and dynamics of G1TE, a nonphosphorylated cyclic peptide inhibitor for the Grb2 SH2 domain.

S. Tzeng, P. Roller, F. Lung, 1999, Archives of biochemistry and biophysics.

Potent Grb2-SH2 domain antagonists not relying on phosphotyrosine mimics.

Dajun Yang, Megan L Peach, Manchao Zhang, 2003, Bioorganic & medicinal chemistry letters.

Synthesis, purification and mutagenicity of 2-hydroxyamino-3-methylimidazolo[4,5-f]quinoline.

S. Thorgeirsson, R. Adamson, P. Roller, 1987, Carcinogenesis.

Global optimization of conformational constraint on non-phosphorylated cyclic peptide antagonists of the Grb2-SH2 domain.

P. Roller, F. Lung, Y. Long, 2003, Bioorganic & medicinal chemistry.

In vitro and in vivo metabolism of all-trans- and 13-cis-retinoic acid in hamsters. Identification of 13-cis-4-oxoretinoic acid.

M. Sporn, P. Roller, C. Frolik, 1980, The Journal of biological chemistry.

Biotransformation and biological activity of N-(4-hydroxyphenyl)retinamide derivatives in rodents.

M. Sporn, D. Newton, P. Roller, 1981, The Journal of pharmacology and experimental therapeutics.

Synthesis of phosphonomethyl-phenylalanine and phosphotyrosine containing cyclic peptides as inhibitors of protein tyrosine kinase/SH2 interactions

P. Roller, A. Otaka, M. Nomizu, 1994 .

Binding affinity difference induced by the stereochemistry of the sulfoxide bridge of the cyclic peptide inhibitors of Grb2-SH2 domain: NMR studies for the structural origin.

Yan-Li Song, P. Roller, Y. Long, 2005, Biochemical and biophysical research communications.

Structure-based design of thioether-bridged cyclic phosphopeptides binding to Grb2-SH2 domain.

Dajun Yang, P. Roller, Manchao Zhang, 2003, Bioorganic & medicinal chemistry letters.

High affinity nonphosphorylated cyclic peptide inhibitors of Grb2-SH2/growth factor receptor interactions

Dajun Yang, P. Roller, T. Burke, 2002 .

Secondary structure of proteins associated in thin films

P. Roller, D. Gajdusek, G. Ruben, 1993, Biopolymers.

The NMR identification of the ring A protons of C‐3 oxygenated steroids using the lanthanide paramagnetic shift technique

P. Roller, O. R. Rodig, 1974 .

Bicyclic Peptide Inhibitors of an Epithelial Cell-Derived Transmembrane Protease, Matriptase

I. Enyedy, Shaomeng Wang, R. Dickson, 2001 .

Current Synthetic Approaches to Peptide and Peptidomimetic Cyclization

P. Roller, P. Li, Jie Xu, 2002 .

New HIV-1 reverse transcriptase inhibitors based on a tricyclic benzothiophene scaffold: synthesis, resolution, and inhibitory activity.

J. Deschamps, V. Pathak, K. Krajewski, 2006, Bioorganic & medicinal chemistry letters.

New HIV‐1 Reverse Transcriptase Inhibitors Based on a Tricyclic Benzothiophene Scaffold; Synthesis, Resolution, and Inhibitory Activity.

J. Deschamps, V. Pathak, K. Krajewski, 2006 .

Pyrogallol-based molecules as potent inhibitors of the antiapoptotic Bcl-2 proteins.

Sheng Jiang, Renxiao Wang, Su Qiu, 2007, Journal of medicinal chemistry.

Mechanism of laminin chain assembly into a triple-stranded coiled-coil structure.

A. Utani, P. Roller, K. Beck, 1996, Biochemistry.

Identification of Cell Binding Sites in the Laminin α1 Chain Carboxyl-terminal Globular Domain by Systematic Screening of Synthetic Peptides (*)

A. Utani, H. Kleinman, P. Roller, 1995, The Journal of Biological Chemistry.

Structure-based discovery of nonpeptidic small organic compounds to block the T cell response to myelin basic protein.

Chao-Yie Yang, Xiongwu Wu, Yipin Lu, 2004, Journal of medicinal chemistry.

Potentiating effect of distant sites in non-phosphorylated cyclic peptide antagonists of the Grb2-SH2 domain.

Dajun Yang, Dajun Yang, P. Roller, 2003, Biochemical and biophysical research communications.

STEREOCHEMISTRY OF THE HYDROLYSIS PRODUCTS AND THEIR ACETONIDES OF TWO STEREOISOMERIC BENZO(A)PYRENE 7,8-DIOL 9,10-EPOXIDES

P. Roller, H. Gelboin, D. McCourt, 1977 .

4'-O-[2-(2-fluoromalonyl)]-L-tyrosine: a phosphotyrosyl mimic for the preparation of signal transduction inhibitory peptides.

M. Akamatsu, S. Shoelson, P. Roller, 1996, Journal of medicinal chemistry.

Synthesis of a disulphide linked heterotrimeric active site peptide segment of laminin

A. Utani, P. Roller, M. Nomizu, 1991 .

Distribution, frequency, and quantitative analysis of estrogen, progesterone, androgen, and glucocorticoid receptors in human breast cancer.

G. Hortobagyi, E. Gehan, D. Greenblatt, 1979, Cancer research.

Terpenoids. Part LXVI. Simultaneous functionalization of the angular 10- and 13-methyl groups in 11β-hydroxylanostan-3β-yl acetate by oxidation with lead tetra-acetate–iodine

C. Djerassi, P. Roller, 1970 .

Protein-tyrosine phosphatase inhibition by a peptide containing the phosphotyrosyl mimetic, L-O-malonyltyrosine.

D. Barford, M. Akamatsu, P. Roller, 1995, Biochemical and biophysical research communications.

Conformational studies of N-terminal segments of ras p21 proteins

Kyou-Hoon Han, P. Roller, C. Niu, 1988 .

The amino terminus of ADP-ribosylation factor (ARF) is a critical determinant of ARF activities and is a potent and specific inhibitor of protein transport.

J. Rothman, L. Orci, R. Kahn, 1992, The Journal of biological chemistry.

Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening.

I. Enyedy, Y. Tomita, P. Roller, 2001, Journal of medicinal chemistry.

N-Formylation of an aromatic amine as a metabolic pathway.

P. Roller, E. Weisburger, T. Benjamin, 1979, Xenobiotica; the fate of foreign compounds in biological systems.

L-O-(2-malonyl)tyrosine: a new phosphotyrosyl mimetic for the preparation of Src homology 2 domain inhibitory peptides.

M. Akamatsu, S. Shoelson, P. Roller, 1995, Journal of medicinal chemistry.

A dual-readout F2 assay that combines fluorescence resonance energy transfer and fluorescence polarization for monitoring bimolecular interactions.

R. Dingledine, H. Fu, Shaomeng Wang, 2011, Assay and drug development technologies.

Design and Synthesis of a New, Conformationally Constrained, Macrocyclic Small-Molecule Inhibitor of STAT3 via “Click Chemistry”.

Shaomeng Wang, Z. Nikolovska-Coleska, Wei-Lin Gao, 2007 .

Deprotection and cleavage methods for protected peptide resins containing 4-[(diethylphosphono)difluoromethyl]-D,L-phenylalanine residues

P. Roller, T. Burke, A. Otaka, 1993 .

Mass spectrometry of N-acylated daunorubicin derivatives.

P. Roller, M. Sutphin, A. Aszalós, 1976, Biomedical mass spectrometry.

Synthetic Studies in the Veratrum Alkaloid Series. I. Introduction and the Total Synthesis of Appropriate C-Nor-D-homo Steroid Derivatives

P. Roller, J. Kutney, T. Inaba, 1975 .