P. Schaffer

发表

Properties of the novel herpes simplex virus type 1 origin binding protein, OBPC

M. A. Hardwicke, K. Baradaran, C. Dabrowski, 1996, Journal of virology.

Cloning and characterization of herpes simplex virus type 1 oriL: comparison of replication and protein-DNA complex formation by oriL and oriS

M. A. Hardwicke, P. Schaffer, 1995, Journal of virology.

Induction of herpes simplex virus type 1 immediate-early gene expression by a cellular activity expressed in Vero and NB41A3 cells after growth arrest-release

P. Schaffer, W. Ralph, M. Cabatingan, 1994, Journal of virology.

Cloning, sequencing, and functional analysis of oriL, a herpes simplex virus type 1 origin of DNA synthesis

Schaffer, A. Murray, A. Maxam, 1985, Molecular and cellular biology.

The herpes simplex virus immediate-early protein, ICP4, is required to potentiate replication of human immunodeficiency virus in CD4+ lymphocytes

Albrecht, S. Hammer, N. DeLuca, 1989, Journal of virology.

Molecular mimicry by herpes simplex virus-type 1: autoimmune disease after viral infection.

H Cantor, F. Granucci, P. Schaffer, 1998, Science.

Persistent elevated expression of cytokine transcripts in ganglia latently infected with herpes simplex virus in the absence of ganglionic replication or reactivation.

P. Schaffer, D. Coen, D. Knipe, 2000, Virology.

Antiherpesvirus drugs: a promising spectrum of new drugs and drug targets

Priscilla A. Schaffer, Donald M. Coen, P. Schaffer, 2003, Nature Reviews Drug Discovery.

Excretion of non-infectious virus particles lacking glycoprotein H by a temperature-sensitive mutant of herpes simplex virus type 1: evidence that gH is essential for virion infectivity.

P. Desai, P. Schaffer, A. Minson, 1988, The Journal of general virology.

A virion-associated glycoprotein essential for infectivity of herpes simplex virus type 1.

P. Schaffer, S. Little, R. Courtney, 1981, Virology.

Genetic analysis of temperature-sensitive mutants of HSV-1: the combined use of complementation and physical mapping for cistron assignment.

S. Weller, P. Schaffer, D. Coen, 1983, Virology.

A viral function represses accumulation of transcripts from productive-cycle genes in mouse ganglia latently infected with herpes simplex virus

P. Schaffer, D. Coen, S. H. Chen, 1997, Journal of virology.

A LAT-associated function reduces productive-cycle gene expression during acute infection of murine sensory neurons with herpes simplex virus type 1

P. Schaffer, D. Knipe, D. Garber, 1997, Journal of virology.

Roscovitine, a Specific Inhibitor of Cellular Cyclin-Dependent Kinases, Inhibits Herpes Simplex Virus DNA Synthesis in the Presence of Viral Early Proteins

P. Schaffer, L. Schang, A. Rosenberg, 2000, Journal of Virology.

Activation of gene expression by herpes simplex virus type 1 ICP0 occurs at the level of mRNA synthesis

R. Jordan, P. Schaffer, Robert Jordan, 1997, Journal of virology.

An activity specified by the osteosarcoma line U2OS can substitute functionally for ICP0, a major regulatory protein of herpes simplex virus type 1

P. Schaffer, F. Yao, Feng Yao, 1995, Journal of virology.

Recruitment of activated IRF-3 and CBP/p300 to herpes simplex virus ICP0 nuclear foci: Potential role in blocking IFN-beta induction.

P. Schaffer, D. Knipe, G. T. Melroe, 2007, Virology.

Cathepsin B Mediates Cleavage of Herpes Simplex Virus Type 1 Origin Binding Protein (OBP) To Yield OBPC-1, and Cleavage Is Dependent upon Viral DNA Replication

P. Schaffer, L. A. Silva, Malen A. Link, 2007, Journal of Virology.

Herpes simplex virus type 1 ICP27 deletion mutants exhibit altered patterns of transcription and are DNA deficient

L. McMahan, P. Schaffer, A. M. McCarthy, 1989, Journal of virology.

Activation of immediate-early, early, and late promoters by temperature-sensitive and wild-type forms of herpes simplex virus type 1 protein ICP4

N. DeLuca, P. Schaffer, 1985, Molecular and cellular biology.

Prolonged gene expression and cell survival after infection by a herpes simplex virus mutant defective in the immediate-early genes encoding ICP4, ICP27, and ICP22

Simon C Watkins, N. DeLuca, P. Schaffer, 1996, Journal of virology.

ICP22 and the UL13 Protein Kinase Are both Required for Herpes Simplex Virus-Induced Modification of the Large Subunit of RNA Polymerase II

P. Schaffer, C. Spencer, M. C. Long, 1999, Journal of Virology.

The Products of the Herpes Simplex Virus Type 1 Immediate-Early US1/US1.5 Genes Downregulate Levels of S-Phase-Specific Cyclins and Facilitate Virus Replication in S-Phase Vero Cells

P. Schaffer, T. Astor, Joseph S. Orlando, 2006, Journal of Virology.

ICP22 Is Required for Wild-Type Composition and Infectivity of Herpes Simplex Virus Type 1 Virions

P. Schaffer, D. Knipe, J. W. Balliet, 2006, Journal of Virology.

Suppression de l'activite de kinase cycline-dependante pour la prevention et le traitement des infections

L. Meijer, P. Schaffer, L. Schang, 2001 .

The Differential Requirement for Cyclin-Dependent Kinase Activities Distinguishes Two Functions of Herpes Simplex Virus Type 1 ICP0

P. Schaffer, G. Maul, D. Davido, 2003, Journal of Virology.

The Cyclin-Dependent Kinase Inhibitor Roscovitine Inhibits the Transactivating Activity and Alters the Posttranslational Modification of Herpes Simplex Virus Type 1 ICP0

P. Schaffer, D. Leib, D. Davido, 2002, Journal of Virology.

Modification of Herpes Simplex Virus Type Activity and Alters the Posttranslational Roscovitine Inhibits the Transactivating the Cyclin-dependent Kinase Inhibitor

P. Schaffer, D. Leib, D. Davido, 2022 .

Human PC4 Is a Substrate-specific Inhibitor of RNA Polymerase II Phosphorylation*

A. Shilatifard, R. Shiekhattar, D. Speicher, 2000, The Journal of Biological Chemistry.

Evidence that hepatocyte turnover is required for rapid clearance of duck hepatitis B virus during antiviral therapy of chronically infected ducks

J. Cullen, P. Schaffer, W. Mason, 1994, Journal of virology.

A dominant lethal temperature-sensitive mutant of herpes simplex virus type 1.

P. Schaffer, R. Courtney, J. Jofre, 1981, Virology.

Synthesis of virus-specific polypaptides by temperature-sensitive mutants of herpes simplex virus type 1.

K. Powell, P. Schaffer, R. Courtney, 1976, Virology.

Deletion mutants in the gene encoding the herpes simplex virus type 1 immediate-early protein ICP0 exhibit impaired growth in cell culture

P. Schaffer, W. Sacks, 1987, Journal of virology.

A rapid procedure for the enrichment of undenaturated, antigenically active herpes simplex virus glycoproteins.

P. Schaffer, R. Respess, B. A. Pancake, 1984, Journal of virological methods.

Herpes simplex virus type 1 ICP27 is an essential regulatory protein

P. Schaffer, D. Aschman, W. Sacks, 1985, Journal of virology.

Temperature-sensitive mutants in herpes simplex virus type 1 ICP4 permissive for early gene expression

N. DeLuca, P. Schaffer, M. Courtney, 1984, Journal of virology.

Collaborative complementation study of temperature-sensitive mutants of herpes simplex virus types 1 and 2

P. Schaffer, M. Timbury, V. Carter, 1978, Journal of virology.

Thymidine kinase activity of biochemically transformed mouse cells after superinfection by thymidine kinase-negative, temperature-sensitive, herpes simplex virus mutants.

D. R. Dubbs, P. Schaffer, S. Kit, 1978, Virology.

Herpes simplex virus gene products involved in the induction of chromosomal aberrations.

P. Schaffer, C. Celluzzi, F. Farber, 1986, Virus research.

Fine mapping and molecular cloning of mutations in the herpes simplex virus DNA polymerase locus

S. Weller, P. Schaffer, D. Coen, 1984, Journal of virology.

Mutations in the herpes simplex virus DNA polymerase gene conferring hypersensitivity to aphidicolin.

P. Schaffer, D. Coen, D. Aschman, 1983, Nucleic acids research.

Physical and genetic analysis of the herpes simplex virus DNA polymerase locus.

C. Crumpacker, P. Schaffer, N. Wilkie, 1980, Virology.

Mutations in the herpes simplex virus DNA polymerase gene can confer resistance to 9-beta-D-arabinofuranosyladenine

P. Schaffer, D. Coen, P. Furman, 1982, Journal of virology.

Acyclovir-resistant mutants of herpes simplex virus type 1 express altered DNA polymerase or reduced acyclovir phosphorylating activities

P. Schaffer, D. Coen, P. Furman, 1981, Journal of virology.

Involvement of eucaryotic deoxyribonucleic acid polymerases alpha and gamma in the replication of cellular and viral deoxyribonucleic acid.

M. DePamphilis, P. Schaffer, H. Krokan, 1979, Biochemistry.

Cellular Stress Rather than Stage of the Cell Cycle Enhances the Replication and Plating Efficiencies of Herpes Simplex Virus Type 1 ICP0− Viruses

P. Schaffer, R. M. Bringhurst, 2006, Journal of Virology.

ICP0 Is Required for Efficient Reactivation of Herpes Simplex Virus Type 1 from Neuronal Latency

W. Halford, P. Schaffer, 2001, Journal of Virology.

Temperature-sensitive mutants of herpesviruses.

P. Schaffer, 1975, Current topics in microbiology and immunology.

Recombination between temperature-sensitive mutants of herpes simplex virus type 1.

P. Schaffer, M. J. Tevethia, M. Benyesh-Melnick, 1974, Virology.

The repressing and enhancing functions of the herpes simplex virus regulatory protein ICP27 map to C-terminal regions and are required to modulate viral gene expression very early in infection

L. McMahan, P. Schaffer, Priscilla A. Schaffer, 1990, Journal of virology.

Herpes simplex virus type 1 ICP0 regulates expression of immediate-early, early, and late genes in productively infected cells

P. Schaffer, W. Cai, 1992, Journal of virology.

Herpes simplex virus type 1 ICP0 plays a critical role in the de novo synthesis of infectious virus following transfection of viral DNA

P. Schaffer, W. Cai, 1989, Journal of virology.

Biochemical transformation by temperature-sensitive mutants of herpes simplex virus type 1

F. Rapp, P. Schaffer, N. Turner, 1980, Journal of virology.

Elements in the transcriptional regulatory region flanking herpes simplex virus type 1 oriS stimulate origin function

P. Schaffer, S. Wong, 1991, Journal of virology.

A cellular function can enhance gene expression and plating efficiency of a mutant defective in the gene for ICP0, a transactivating protein of herpes simplex virus type 1

P. Schaffer, W. Cai, Priscilla A. Schaffer, 1991, Journal of virology.

Intracellular localization of the herpes simplex virus type 1 major transcriptional regulatory protein, ICP4, is affected by ICP27

P. Schaffer, Zhimin Zhu, Z. Zhu, 1995, Journal of virology.

Physical interaction between the herpes simplex virus type 1 immediate-early regulatory proteins ICP0 and ICP4

P. Schaffer, F. Yao, Feng Yao, 1994, Journal of virology.

A novel class of transcripts expressed with late kinetics in the absence of ICP4 spans the junction between the long and short segments of the herpes simplex virus type 1 genome

P. Schaffer, L. Yeh, 1993, Journal of virology.

The herpes simplex virus type 1 regulatory protein ICP0 enhances virus replication during acute infection and reactivation from latency

P. Schaffer, D. Coen, T. Astor, 1993, Journal of virology.

DNA synthesis and DNA polymerase activity of herpes simplex virus type 1 temperature-sensitive mutants

P. Schaffer, D. Purifoy, G. M. Aron, 1975, Journal of virology.

Optimized Viral Dose and Transient Immunosuppression Enable Herpes Simplex Virus ICP0-Null Mutants To Establish Wild-Type Levels of Latency In Vivo

W. Halford, P. Schaffer, 2000, Journal of Virology.

The involvement of herpes simplex virus type 1 glycoproteins in cell-mediated immunity.

P. Schaffer, S. Tevethia, V. Carter, 1981, Journal of immunology.

Anatomy of herpes simplex virus (HSV) DNA. X. Mapping of viral genes by analysis of polypeptides and functions specified by HSV-1 X HSV-2 recombinants

B Roizman, P. Schaffer, B. Roizman, 1978, Journal of virology.

Genetic analysis of temperature-sensitive mutants which define the genes for the major herpes simplex virus type 2 DNA-binding protein and a new late function

R. Dixon, P. Schaffer, D. Sabourin, 1983, Journal of Virology.

Characterization of the antiviral effects of 2′ carbodeoxyguanosine in ducks chronically infected with duck hepatitis B virus

Tsung-Teh Wu, E. Lustbader, J. Cullen, 1994, Hepatology.

Glutamine Deprivation Causes Enhanced Plating Efficiency of a Herpes Simplex Virus Type 1 ICP0-Null Mutant

P. Schaffer, R. M. Bringhurst, Antonia A Dominguez, 2008, Journal of Virology.

Temperature-sensitive mutants of herpes simplex virus type 1: isolation, complementation and partial characterization.

P. Schaffer, N. Biswal, M. Benyesh-Melnick, 1973, Virology.

Complementation of adeno-associated satellite viral antigens and infectious DNA by temperature-sensitive mutants of herpes simplex virus.

P. Schaffer, H. D. Mayor, J. Esparza, 1974, Virology.

Genetics of herpes simplex virus.

S. Weller, P. Schaffer, D. Coen, 1984, The Journal of investigative dermatology.

Physical mapping of herpes simplex virus type 1 ts mutants by marker rescue: correlation of the physical and genetic maps.

R. Dixon, D. Parris, P. Schaffer, 1980, Virology.

Anatomy of Herpes Simplex Virus DNA. IX. Apparent Exclusion of Some Parental DNA Arrangements in the Generation of Intertypic (HSV-1 × HSV-2) Recombinants

P. Schaffer, B. Roizman, T. Buchman, 1977, Journal of virology.

Temperature-sensitive mutants of herpes simplex virus.

P. Schaffer, V. Vonka, M. Benyesh-Melnick, 1970, Virology.

Genetic and phenotypic analysis of herpes simplex virus type 1 mutants conditionally resistant to immune cytolysis

P. Schaffer, D. Aschman, B. A. Pancake, 1983, Journal of virology.

Two distinct loci confer resistance to acycloguanosine in herpes simplex virus type 1.

P. Schaffer, D. Coen, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Requirement for Cellular Cyclin-Dependent Kinases in Herpes Simplex Virus Replication and Transcription

P. Schaffer, L. Schang, J. Phillips, 1998, Journal of Virology.

and Transcription Kinases in Herpes Simplex Virus Replication Requirement for Cellular Cyclin-Dependent

P. Schaffer, L. Schang, J. Phillips, 1998 .

Viral gene functions expressed and detected by temperature-sensitive mutants of herpes simplex virus.

P. Schaffer, R. Courtney, M. Benyesh-Melnick, 1975, Cold Spring Harbor symposia on quantitative biology.

Generation of genetic diversity in herpes simplex virus: an antimutator phenotype maps to the DNA polymerase locus.

J. Hall, P. Schaffer, D. Coen, 1984, Virology.

New anti-HSV therapeutics target the helicase–primase complex

C. Crumpacker, P. Schaffer, 2002, Nature Medicine.

Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency

K. Tyler, P. Schaffer, D. Coen, 1989, Journal of virology.

Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate.

K. Tyler, P. Schaffer, D. Coen, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Point Mutations in Herpes Simplex Virus Type 1 oriL, but Not in oriS, Reduce Pathogenesis during Acute Infection of Mice and Impair Reactivation from Latency

P. Schaffer, J. W. Balliet, 2006, Journal of Virology.

A deletion mutant of the latency-associated transcript of herpes simplex virus type 1 reactivates from the latent state with reduced frequency

P. Schaffer, D. Coen, D. Knipe, 1989, Journal of virology.

The promoter of the latency-associated transcripts of herpes simplex virus type 1 contains a functional cAMP-response element: role of the latency-associated transcripts and cAMP in reactivation of viral latency.

K. Nadeau, P. Schaffer, D. Leib, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Ultrastructural characterization of an early, nonstructural polypeptide of herpes simplex virus type 1

P. Schaffer, G. Cabral, F. Marciano-cabral, 1980, Journal of virology.

Construction and characterization of a herpes simplex virus type I recombinant expressing green fluorescent protein: acute phase replication and reactivation in mice.

P. Schaffer, J. W. Balliet, Anna S. Kushnir, 2007, Virology.

Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4

N. DeLuca, P. Schaffer, A. M. McCarthy, 1985, Journal of virology.

Differential effects of nerve growth factor and dexamethasone on herpes simplex virus type 1 oriL- and oriS-dependent DNA replication in PC12 cells

M. A. Hardwicke, P. Schaffer, 1997, Journal of virology.

Site-Directed Mutagenesis of Large DNA Palindromes: Construction and In Vitro Characterization of Herpes Simplex Virus Type 1 Mutants Containing Point Mutations That Eliminate the oriL or oriS Initiation Function

P. Schaffer, M. Cabatingan, J. W. Balliet, 2005, Journal of Virology.

Explant-Induced Reactivation of Herpes Simplex Virus Occurs in Neurons Expressing Nuclear cdk2 and cdk4

P. Schaffer, L. Schang, A. Bantly, 2002, Journal of Virology.

Specific inhibitors of herpes simplex virus thymidine kinase diminish reactivation of latent virus from explanted murine ganglia

P. Schaffer, D. Coen, D. Leib, 1990, Antimicrobial Agents and Chemotherapy.

Herpes Simplex Virus 1 ICP0 Phosphorylation Site Mutants Are Attenuated for Viral Replication and Impaired for Explant-Induced Reactivation

P. Schaffer, H. Mostafa, Lisa A. Pitcher, 2011, Journal of Virology.

Herpes Simplex Virus Glycoproteins: Isolation of Mutants Resistant to Immune Cytolysis

P. Schaffer, R. Eberle, S. Tevethia, 1980, Journal of virology.

A herpes simplex virus ribonucleotide reductase deletion mutant is defective for productive acute and reactivatable latent infections of mice and for replication in mouse cells.

S. Weller, P. Schaffer, D. Coen, 1989, Virology.

Thymidine kinase activity of herpes simplex virus temperature-sensitive mutants.

P. Schaffer, S. Kit, R. Courtney, 1973, Intervirology.

GENETICS OF HERPESVIRUS

P. Schaffer, R. Courtney, 1976 .

Oncogenic transformation of primary hamster cells by herpes simplex virus type 2 (HSV‐2) and an HSV‐2 temperature‐sensitive mutant

B. Levy, P. Schaffer, S. Kimura, 1975, International journal of cancer.

Isolation, complementation and preliminary phenotypic characterization of temperature-sensitive mutants of herpes simplex virus type 2.

P. Schaffer, D. Purifoy, M. Benyesh-Melnick, 1974, Virology.

Expression of an early, nonstructural antigen of herpes simplex virus in cell transformed in vitro by herpes simplex virus

P. Schaffer, R. Courtney, V. L. Flannery, 1977, Journal of virology.

Electron microscopic studies of temperature-sensitive mutants of herpes simplex virus type 1.

P. Schaffer, J. Brunschwig, M. Benyesh-Melnick, 1974, Virology.

Transfer and expression of the lacZ gene in rat brain neurons mediated by herpes simplex virus mutants.

R. Martuza, X. Breakefield, N. DeLuca, 1990, The New biologist.

Activities of herpes simplex virus type 1 (HSV-1) ICP4 genes specifying nonsense peptides.

N. DeLuca, P. Schaffer, N. DeLuca, 1987, Nucleic acids research.

The carbocyclic analog of 2'-deoxyguanosine induces a prolonged inhibition of duck hepatitis B virus DNA synthesis in primary hepatocyte cultures and in the liver

P. Schaffer, W. Mason, I. Fourel, 1994, Journal of virology.

A temperature-sensitive mutation in a herpes simplex virus type 1 gene required for viral DNA synthesis maps to coordinates 0.609 through 0.614 in UL

C. Smith, P. Schaffer, M. Marchetti, 1988, Journal of virology.

Genetics of resistance to phosphonoacetic acid in strain KOS of herpes simplex virus type 1

D. Parris, P. Schaffer, J. Jofre, 1977, Journal of virology.

Pharmacological Cyclin-Dependent Kinase Inhibitors Inhibit Replication of Wild-Type and Drug-Resistant Strains of Herpes Simplex Virus and Human Immunodeficiency Virus Type 1 by Targeting Cellular, Not Viral, Proteins

L. Meijer, M. Malim, N. Gray, 2002, Journal of Virology.

Ultrastructural Characterization ofan Early, Nonstructural Polypeptide ofHerpesSimplex Virus Type1

P. Schaffer, G. Cabral, R. Courtney, 1980 .

DNA-negative temperature-sensitive mutants of herpes simplex virus type 1: patterns of viral DNA synthesis after temperature shift-up

P. Schaffer, R. Courtney, D. Bone, 1976, Journal of virology.

Biochemical and genetic analysis of acyclovir-resistant mutants of herpes simplex virus type 1.

P. Schaffer, D. Coen, P. Keller, 1982, The American journal of medicine.

GENETICS OF ACYCLOGUANOSINE RESISTANCE AND THE THYMIDINE KINASE GENE IN HSV-1

R. Dixon, P. Schaffer, D. Coen, 1980 .

Localization of the herpes simplex virus type 1 65-kilodalton DNA-binding protein and DNA polymerase in the presence and absence of viral DNA synthesis

C. Crumpacker, D. Parris, P. Schaffer, 1990, Journal of virology.

Genetic analysis of temperature-sensitive mutants which define the gene for the major herpes simplex virus type 1 DNA-binding protein

S. Weller, P. Schaffer, K. Lee, 1983, Journal of virology.

Hydroxylamine mutagenesis of HSV DNA and DNA fragments: introduction of mutations into selected regions of the viral genome.

R. Dixon, D. Parris, P. Schaffer, 1979, Virology.

Transcriptional analysis of the region of the herpes simplex virus type 1 genome containing the UL8, UL9, and UL10 genes and identification of a novel delayed-early gene product, OBPC

K. Baradaran, C. Dabrowski, P. Schaffer, 1994, Journal of virology.

Electron microscope studies of temperature-sensitive mutants of herpes simplex virus type 2

P. Schaffer, G. Cabral, 1976, Journal of virology.

Intertypic complementation and recombination between temperature-sensitive mutants of herpes simplex virus types 1 and 2.

P. Schaffer, J. Esparza, B. Benyesh-Melnick, 1976, Virology.

Qualitative Complementation Test for Temperature-Sensitive Mutants of Herpes Simplex Virus

P. Schaffer, C. T. Chu, 1975, Journal of virology.

Replication Cleavage Is Dependent upon Viral DNA Protein ( OBP ) To Yield OBPC-1 , and Simplex Virus Type 1 Origin Binding Cathepsin B Mediates Cleavage of Herpes

P. Schaffer, L. A. Silva, Malen A. Link, 2007 .

Phosphorylation of the Herpes Simplex Virus Type 1 Origin Binding Protein

P. Schaffer, J. Isler, 2001, Journal of Virology.

Cellular protein interactions with herpes simplex virus type 1 oriS

C. Dabrowski, P. Schaffer, P. Carmillo, 1994, Molecular and cellular biology.

Herpes simplex virus type 1 origin-specific binding protein: oriS-binding properties and effects of cellular proteins

C. Dabrowski, P. Schaffer, 1991, Journal of virology.

Cell-mediated immunity to herpes simplex virus: specificity of cytotoxic T cells

B. Rouse, P. Schaffer, R. Eberle, 1980, Infection and immunity.

Attenuation of herpesvirus saimiri for marmosets after successive passage in cell culture at 39 degrees C.

P. Schaffer, F. Deinhardt, L. Falk, 1975, Journal of the National Cancer Institute.

Herpes simplex virus type 2 mutants with deletions in the intergenic region between ICP4 and ICP22/47: identification of nonessential cis-acting elements in the context of the viral genome

C. Smith, P. Schaffer, P. Edmonson, 1989, Journal of virology.

Intertypic recombinants of herpes simplex virus types 1 and 2 infected-cell polypeptide 4.

C. Smith, P. Schaffer, 1987, Virology.

Expression of the syncytial (syn) phenotype in HSV-1, strain KOS: genetic and phenotypic studies of mutants in two syn loci.

P. Schaffer, S. Little, 1981, Virology.

Fine-structure mapping and functional analysis of temperature-sensitive mutants in the gene encoding the herpes simplex virus type 1 immediate early protein VP175

R. Dixon, P. Schaffer, 1980, Journal of virology.

Introduction of a foreign gene (Escherichia coli lacZ) into rat neostriatal neurons using herpes simplex virus mutants: A light and electron microscopic study

R. Martuza, X. Breakefield, J. Vonsattel, 1992, Experimental Neurology.

Targeting Cellular , Not Viral , Proteins Immunodeficiency Virus Type 1 by Simplex Virus and Human and Drug-Resistant Strains of Herpes Inhibitors Inhibit Replication of Wild-Type Pharmacological Cyclin-Dependent Kinase

L. Meijer, M. Malim, N. Gray, 2002 .

Physical and functional domains of the herpes simplex virus transcriptional regulatory protein ICP4

N. DeLuca, P. Schaffer, 1988, Journal of virology.

Overexpression of the herpes simplex virus type 1 immediate-early regulatory protein, ICP27, is responsible for the aberrant localization of ICP0 and mutant forms of ICP4 in ICP4 mutant virus-infected cells

N. DeLuca, P. Schaffer, Z. Zhu, 1996, Journal of virology.

Cooperativity among herpes simplex virus type 1 immediate-early regulatory proteins: ICP4 and ICP27 affect the intracellular localization of ICP0

P. Schaffer, Z. Zhu, W. Cai, 1994, Journal of virology.

Ecologic studies of Venezuelan encephalitis virus in southeastern México. 3. Infection of mosquitoes.

P. Schaffer, W. Scherer, R. W. Dickerman, 1971, The American journal of tropical medicine and hygiene.

Phosphorylation Site Mutations Affect Herpes Simplex Virus Type 1 ICP0 Function

William Arbuthnot Sir Lane, P. Schaffer, D. Davido, 2005, Journal of Virology.

ICP0, ICP4, or VP16 Expressed from Adenovirus Vectors Induces Reactivation of Latent Herpes Simplex Virus Type 1 in Primary Cultures of Latently Infected Trigeminal Ganglion Cells

W. Halford, P. Schaffer, C. Kemp, 2001, Journal of Virology.

Cellular Transcription Factors Enhance Herpes Simplex Virus Type 1 oriS-Dependent DNA Replication

P. Schaffer, A. T. Nguyen-Huynh, 1998, Journal of Virology.

Herpes Simplex Virus Type 1 C-Terminal Variants of the Origin Binding Protein (OBP), OBPC-1 and OBPC-2, Cooperatively Regulate Viral DNA Levels In Vitro, and OBPC-2 Affects Mortality in Mice

P. Schaffer, Malen A. Link, 2007, Journal of Virology.

Herpes simplex virus immediate-early protein ICP22 is required for viral modification of host RNA polymerase II and establishment of the normal viral transcription program

P. Schaffer, C. Spencer, V. Lam, 1995, Journal of virology.

Mutants defective in herpes simplex virus type 2 ICP4: isolation and preliminary characterization

C. Smith, P. Schaffer, 1987, Journal of virology.

Temperature-sensitive mutants of herpes simplex virus type 1 defective in transcriptional and post-transcriptional functions required for viral DNA synthesis.

D. Parris, P. Schaffer, R. Courtney, 1978, Virology.

A Virus with a Mutation in the ICP4-Binding Site in the L/ST Promoter of Herpes Simplex Virus Type 1, but Not a Virus with a Mutation in Open Reading Frame P, Exhibits Cell-Type-Specific Expression of γ134.5 Transcripts and Latency-Associated Transcripts

P. Schaffer, L. Y. Lee, 1998, Journal of Virology.

Origin of Expression of the Herpes Simplex Virus Type 1 Protein US1.5

P. Schaffer, J. J. Bowman, 2009, Journal of Virology.

Origin of Expression of the Herpes Simplex Virus Type 1 Protein U S 1.5 (cid:1)

P. Schaffer, J. J. Bowman, 2009 .

Role of Nuclear Factor Y in Stress-Induced Activation of the Herpes Simplex Virus Type 1 ICP0 Promoter

P. Schaffer, D. Davido, Anna S. Kushnir, 2009, Journal of Virology.

Herpes simplex virus type 1 oriL is not required for virus replication or for the establishment and reactivation of latent infection in mice

P. Schaffer, M. Polvino-Bodnar, P. K. Orberg, 1987, Journal of virology.

DNA binding activity is required for EBNA 1-dependent transcriptional activation and DNA replication.

P. Schaffer, M. Polvino-Bodnar, 1992, Virology.

A new paradigm for transcription factor TFIIB functionality

Sang Wook Yoo, Vladimir Gelev, Anna Kushnir, 2014, Scientific Reports.

Experimental infection of squirrel and marmoset monkeys with attenuated Herpesvirus saimiri.

P. Schaffer, F. Deinhardt, L. Falk, 1976, Cancer research.

Brief Communication: Attenuation of Herpesvirus saimiri for Marmosets After Successive Passage in Cell Culture at 39° C

P. Schaffer, F. Deinhardt, L. Falk, 1975 .

Characterization of a Nerve Growth Factor-Inducible Cellular Activity That Enhances Herpes Simplex Virus Type 1 Gene Expression and Replication of an ICP0 Null Mutant in Cells of Neural Lineage

R. Jordan, P. Schaffer, Josh Pepe, 1998, Journal of Virology.

The herpes simplex virus type 1 latency-associated transcript promoter is activated through Ras and Raf by nerve growth factor and sodium butyrate in PC12 cells

P. Schaffer, E. Godshalk, D. P. Frazier, 1996, Journal of virology.

Studies on herpes simplex virus and cancer.

K. Powell, P. Schaffer, M. Melnick, 1976, Cancer research.

Transcription of Herpes Simplex Virus Immediate-Early and Early Genes Is Inhibited by Roscovitine, an Inhibitor Specific for Cellular Cyclin-Dependent Kinases

P. Schaffer, L. Schang, A. Rosenberg, 1999, Journal of Virology.

Transactivation of Herpes Simplex Virus Type 1 Immediate-Early Gene Expression by Virion-Associated Factors Is Blocked by an Inhibitor of Cyclin-Dependent Protein Kinases

R. Jordan, P. Schaffer, L. Schang, 1999, Journal of Virology.

Herpes Simplex Virus Type 1 ICP0 Phosphorylation Mutants Impair the E3 Ubiquitin Ligase Activity of ICP0 in a Cell Type-Dependent Manner

C. Boutell, R. Everett, P. Schaffer, 2008, Journal of Virology.

Frame P Mutations Increase Expression of Spliced or Intron-Containing ICP 0 Transcripts in Mouse Ganglia Latently Infected with Herpes Simplex Virus

P. Schaffer, D. Coen, D. Knipe, 2005 .

Neither LAT nor Open Reading Frame P Mutations Increase Expression of Spliced or Intron-Containing ICP0 Transcripts in Mouse Ganglia Latently Infected with Herpes Simplex Virus

P. Schaffer, D. Coen, D. Knipe, 2002, Journal of Virology.

Identification of cis-acting sequences in the promoter of the herpes simplex virus type 1 latency-associated transcripts required for activation by nerve growth factor and sodium butyrate in PC12 cells

P. Schaffer, E. Godshalk, D. P. Frazier, 1996, Journal of virology.

The use of intertypic recombinants for analysis of gene organization in herpes simplex virus.

P. Schaffer, B. Roizman, L. Pereira, 1978, IARC scientific publications.

Genetic and phenotypic characterization of mutants in four essential genes that map to the left half of HSV-1 UL DNA.

S. Weller, P. Schaffer, D. Goldstein, 1987, Virology.

Stability of virulence and plaque size of Venezuelan encephalitis virus with passage in Mosquitoes (Aedes aegypti).

P. Schaffer, W. Scherer, 1971, American journal of epidemiology.

Marker rescue of temperature-sensitive mutants by defective DNA of herpes simplex virus type 1.

P. Schaffer, N. Biswal, D. Purifoy, 1978, Virology.

Activation of human immunodeficiency virus by herpes simplex virus.

S. Hammer, N. DeLuca, P. Schaffer, 1992, The Journal of infectious diseases.

The Cyclin-Dependent Kinase Inhibitor Roscovitine Inhibits the Transactivating Activity and Alters the Posttranslational Modification of Herpes Simplex Virus Type 1 ICP0

P. Schaffer, D. Leib, D. Davido, 2002, Journal of Virology.

Growth of Venezuelan encephalitis virus and disapperance of coxsackie A, Rous sarcoma, herpes simplex and vaccinia viruses following inoculation of Aedes aegypti and other mosquitoes.

P. Schaffer, W. Scherer, 1974, Journal of medical entomology.

Herpes Simplex Virus Type 1 ICP0 Phosphorylation Mutants Impair the E3 Ubiquitin Ligase Activity of ICP0 in a Cell Type-Dependent Manner

R. Everett, P. Schaffer, A. Orr, 2008, Journal of Virology.