B. Graves

发表

Variable Control of Ets-1 DNA Binding by Multiple Phosphates in an Unstructured Region

L. Kay, Gregory M Lee, L. McIntosh, 2005, Science.

Genomic and biochemical insights into the specificity of ETS transcription factors.

Peter C. Hollenhorst, L. McIntosh, B. Graves, 2011, Annual review of biochemistry.

Equilibrium analysis of high affinity interactions using BIACORE.

B. Graves, D. Myszka, M. Jonsen, 1998, Analytical biochemistry.

DNA binding by the ETS domain

M. Gillespie, B. Graves, Lawrence P. Mclntosh, 1996, Nature.

Expression profiles frame the promoter specificity dilemma of the ETS family of transcription factors.

Peter C. Hollenhorst, David A Jones, B. Graves, 2004, Nucleic acids research.

ETV4 and AP1 transcription factors form multivalent interactions with three sites on the MED25 activator-interacting domain

L. McIntosh, B. Graves, Kathryn S. Evans, 2017, bioRxiv.

Structure of the Ets-1 pointed domain and mitogen-activated protein kinase phosphorylation site.

L. McIntosh, C. Slupsky, B. Graves, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Identification and structural characterization of a CBP/p300-binding domain from the ETS family transcription factor GABP alpha.

L. McIntosh, M. L. Nelson, Hyun-Seo Kang, 2008, Journal of molecular biology.

Sequence-specific DNA binding of the proto-oncoprotein ets-1 defines a transcriptional activator sequence within the long terminal repeat of the Moloney murine sarcoma virus.

B. Graves, R. Bryner, C. V. Gunther, 1990, Genes & development.

Identification of ETS domain proteins in murine T lymphocytes that interact with the Moloney murine leukemia virus enhancer

B. Graves, C. V. Gunther, 1994, Molecular and cellular biology.

Electrostatic repulsion causes anticooperative DNA binding between tumor suppressor ETS transcription factors and JUN–FOS at composite DNA sites

B. Graves, P. Hollenhorst, K. A. Clark, 2018, The Journal of Biological Chemistry.

Inner Workings of a Transcription Factor Partnership

B. Graves, Barbara J. Graves, 1998, Science.

Inhibitory Module of Ets-1 Allosterically Regulates DNA Binding through a Dipole-facilitated Phosphate Contact*

L. McIntosh, B. Graves, Hong Wang, 2002, The Journal of Biological Chemistry.

Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5

L. McIntosh, B. Graves, F. Whitby, 2017, Nucleic acids research.

Inhibition of Ets-1 DNA Binding and Ternary Complex Formation between Ets-1, NF-κB, and DNA by a Designed DNA-binding Ligand*

J. Trauger, P. Dervan, B. Graves, 1999, The Journal of Biological Chemistry.

Auto-Inhibition and Partner Proteins, Core-Binding Factor β (CBFβ) and Ets-1, Modulate DNA Binding by CBFα2 (AML1)

T. Gu, N. Speck, B. Graves, 2000, Molecular and Cellular Biology.

Auto-Inhibition and Partner Proteins , Core-Binding Factor b ( CBF b ) and Ets-1 , Modulate DNA Binding by CBF a 2 ( AML 1 )

N. Speck, B. Graves, T. L. Goetz, 1999 .

STUDIES ON A DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN by

C. Hill, B. Graves, P. Finerty, 2012 .

MECHANISM AND REGULATION OF CHROMATIN REMODELER, RSC by

B. Cairns, Ramya Viswanathan, B. Graves, 2012 .

Development of High-Throughput Screening Assays for Inhibitors of ETS Transcription Factors

Sunil Sharma, B. Graves, D. Bearss, 2017, bioRxiv.

Transactivation of the Moloney murine leukemia virus and T-cell receptor beta-chain enhancers by cbf and ets requires intact binding sites for both proteins

N. Speck, B. Graves, W. Sun, 1995, Journal of virology.

Synergy of aromatic residues and phosphoserines within the intrinsically disordered DNA-binding inhibitory elements of the Ets-1 transcription factor

L. McIntosh, B. Graves, M. Okon, 2014, Proceedings of the National Academy of Sciences.

BIOINFORMATICS The GNUMAP algorithm: unbiased probabilistic mapping of oligonucleotides from next-generation sequencing

W. Johnson, B. Cairns, Q. Snell, 2009 .

Correlations between CNDO/2 charge distribution and 13C NMR chemical shift in 7-acylamino side chains of cephalosporins.

D. B. Boyd, B. Graves, K. Lipkowitz, 1984, The Journal of antibiotics.

THE SPECIFICITY OF DOUBLE-STRANDED RNA ADENOSINE DEAMINASES

K. A. Lehmann, B. Bass, B. Graves, 2012 .

Delineation of transcriptional control signals within the Moloney murine sarcoma virus long terminal repeat

S. McKnight, R. Eisenman, B. Graves, 1985, Molecular and cellular biology.

Isolation of a recombinant copy of the gene encoding C/EBP.

S. McKnight, E. Adashi, B. Graves, 1988, Genes & development.

Interaction of murine ets-1 with GGA-binding sites establishes the ETS domain as a new DNA-binding motif.

B. Graves, M. Jonsen, C. V. Gunther, 1992, Genes & development.

Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family.

Peter C. Hollenhorst, Atul A Shah, B. Graves, 2007, Genes & development.

The ETS gene ETV4 is required for anchorage-independent growth and a cell proliferation gene expression program in PC3 prostate cells.

Peter C. Hollenhorst, B. Graves, P. Hollenhorst, 2010, Genes & cancer.

Specificity within the ets family of transcription factors.

B. Graves, J. M. Petersen, Barbara J. Graves, 1998, Advances in cancer research.

Human RNA Polymerase III transcriptomes and relationships to Pol II promoters, enhancer-binding factors and chromatin domains

Peter C. Hollenhorst, Andrew J. Oler, B. Cairns, 2010, Nature Structural &Molecular Biology.

Conformational Dynamics and the Binding of Specific and Nonspecific DNA by the Autoinhibited Transcription Factor Ets-1.

L. McIntosh, B. Graves, M. Okon, 2016, Biochemistry.

Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses.

S. McKnight, B. Graves, P. Johnson, 1987, Genes & development.

Homologous recognition of a promoter domain common to the MSV LTR and the HSV tk gene

S. McKnight, B. Graves, Peter F. Johnson, 1986, Cell.

DNA Specificity Determinants Associate with Distinct Transcription Factor Functions

Barbara J. Graves, Peter C. Hollenhorst, N. Speck, 2009, PLoS genetics.

ETS-4 Is a Transcriptional Regulator of Life Span in Caenorhabditis elegans

Barbara J. Graves, J. Watts, B. Graves, 2010, PLoS genetics.

Pask integrates hormonal signaling with histone modification via Wdr5 phosphorylation to drive myogenesis

A. Shakya, D. Tantin, J. Rutter, 2016, eLife.

Oncogenic ETS proteins mimic activated RAS/MAPK signaling in prostate cells.

Peter C. Hollenhorst, B. Graves, P. Hollenhorst, 2011, Genes & development.

Microsatellites as EWS/FLI response elements in Ewing's sarcoma

Stephen C. Haroldsen, Peter C. Hollenhorst, L. Jorde, 2008, Proceedings of the National Academy of Sciences.

Expression Program in PC 3 Prostate Cells Is Required for Anchorage-Independent Growth and a Cell Proliferation Gene ETV 4 Gene ETS

Peter C. Hollenhorst, B. Graves, P. Hollenhorst, 2011 .

AUTOINHIBITORY DOMAINS: Modular Effectors

M. Pufall, B. Graves, 2002 .

Autoinhibitory domains: modular effectors of cellular regulation.

M. Pufall, B. Graves, 2002, Annual review of cell and developmental biology.

Electrostatic repulsion causes anticooperative DNA binding between tumor suppressor ETS transcription factors and JUN-FOS at composite DNA sites

B. Graves, P. Hollenhorst, K. A. Clark, 2018, bioRxiv.

ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells

Jason Gertz, B. Welm, B. Graves, 2019, bioRxiv.

ETV4 and AP1 transcription factors form multivalent interactions with three sites on the MED25 activator-interacting domain

L. McIntosh, B. Graves, Kathryn S. Evans, 2017, bioRxiv.

Alkylation interference identifies essential DNA contacts for sequence-specific binding of the eukaryotic transcription factor C/EBP.

B. Graves, J. A. Nye, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Autoinhibition of ETV6 (TEL) DNA binding: appended helices sterically block the ETS domain.

Mark Okon, L. McIntosh, B. Graves, 2012, Journal of molecular biology.

Autoinhibition as a transcriptional regulatory mechanism.

M. Gillespie, B. Graves, D. Cowley, 1998, Cold Spring Harbor symposia on quantitative biology.

Ras/Mitogen-Activated Protein Kinase Signaling Activates Ets-1 and Ets-2 by CBP/p300 Recruitment

C. Foulds, M. L. Nelson, B. Graves, 2004, Molecular and Cellular Biology.

Characterization of the cooperative function of inhibitory sequences in Ets-1

B. Graves, M. Jonsen, J. M. Petersen, 1996, Molecular and cellular biology.

Structural coupling of the inhibitory regions flanking the ETS domain of murine Ets‐1

L. McIntosh, B. Graves, L. Donaldson, 1996, Protein science : a publication of the Protein Society.

Solution structure of the ETS domain from murine Ets‐1: a winged helix‐turn‐helix DNA binding motif.

L. McIntosh, B. Graves, L. Donaldson, 1996, The EMBO journal.

Solution structure oftheETSdomainfrommurine Ets-1: a wingedhelix-turn-helix DNAbinding motif

L. McIntosh, B. Graves, J. M. Petersen, 1996 .

Steric mechanism of auto-inhibitory regulation of specific and non-specific DNA binding by the ETS transcriptional repressor ETV6.

Mark Okon, M. Murphy, L. McIntosh, 2014, Journal of molecular biology.

Regulation of lymphoid-specific immunoglobulin mu heavy chain gene enhancer by ETS-domain proteins.

B. Erman, B. Graves, R. Sen, 1993, Science.

The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor.

M. Murphy, L. McIntosh, B. Graves, 2019, Journal of molecular biology.

Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibition.

B. Graves, D. Cowley, Dale O. Cowley, 2000, Genes & development.

Signals and Combinatorial Functions of Histone Modifications

L. McIntosh, B. Graves, P. Hollenhorst, 2013 .

Structural Analysis of the Autoinhibition of Ets-1 and Its Role in Protein Partnerships*

C. Garvie, C. Wolberger, M. Pufall, 2002, The Journal of Biological Chemistry.

Modulation of transcription factor Ets-1 DNA binding: DNA-induced unfolding of an alpha helix.

T. Alber, L. McIntosh, B. Graves, 1995, Science.

Transcription saga tells developmental stories

B. Graves, J. Tamkun, 2006, Development.

Alternate utilization of two regulatory domains within the Moloney murine sarcoma virus long terminal repeat

S. McKnight, B. Graves, D. Coen, 1985, Molecular and cellular biology.

The GNUMAP algorithm: unbiased probabilistic mapping of oligonucleotides from next-generation sequencing

Mark J. Clement, Quinn Snell, Barbara J. Graves, 2010, Bioinform..

CBP/p300 Recruitment Signaling Activates Ets-1 and Ets-2 by Ras/Mitogen-Activated Protein Kinase

C. Foulds, M. L. Nelson, B. Graves, 2014 .

Gene deregulation and chronic activation in natural killer cells deficient in the transcription factor ETS1.

M. Sigvardsson, B. Kee, B. Graves, 2012, Immunity.

An ERK2 docking site in the Pointed domain distinguishes a subset of ETS transcription factors.

B. Graves, J. Seidel, J. J. Seidel, 2002, Genes & development.

Alternate Utilization ofTwoRegulatory DomainsWithin the Moloney MurineSarcoma VirusLongTerminal Repeat

B. Graves, D. Coen, Andsteven L. McKNIGHTt, 1985 .

Role of Ets‐1 phosphorylation in the effector function of Th cells

B. Graves, I. Ho, R. Grenningloh, 2008, European journal of immunology.

Identification and Structural Characterization of a CBP/p300-Binding Domain from the ETS Family Transcription Factor GABP α

L. McIntosh, M. L. Nelson, Hyun-Seo Kang, 2008 .

Auto-Inhibition of Ets-1 Is Counteracted by DNA Binding Cooperativity with Core-Binding Factor α2

T. Gu, N. Speck, B. Graves, 2000, Molecular and Cellular Biology.

Secondary structure of the ETS domain places murine Ets-1 in the superfamily of winged helix-turn-helix DNA-binding proteins.

L. McIntosh, B. Graves, L. Donaldson, 1994, Biochemistry.

Interaction of the Jhd2 Histone H3 Lys-4 Demethylase with Chromatin Is Controlled by Histone H2A Surfaces and Restricted by H2B Ubiquitination*

B. Cairns, M. Kasten, M. Horikoshi, 2015, The Journal of Biological Chemistry.

The affinity of Ets-1 for DNA is modulated by phosphorylation through transient interactions of an unstructured region.

Gregory M Lee, L. McIntosh, M. Pufall, 2008, Journal of molecular biology.

The Structural and Dynamic Basis of Ets-1 DNA Binding Autoinhibition*

Barbara J. Graves, Logan W. Donaldson, Gregory M Lee, 2005, Journal of Biological Chemistry.

Ras signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to coactivator CBP

Gregory M Lee, L. McIntosh, M. L. Nelson, 2010, Proceedings of the National Academy of Sciences.

Ets-1 flips for new partner Pax-5.

M. Pufall, B. Graves, 2002, Structure.

Autoinhibition of ETV6 DNA Binding Is Established by the Stability of Its Inhibitory Helix.

L. McIntosh, B. Graves, Soumya De, 2016, Journal of molecular biology.

Identification of the discontinuous binding site in human interleukin 1 beta for the type I interleukin 1 receptor.

M. Hatada, B. Graves, V. Madison, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Site-directed mutagenesis--molecular biology and rational drug design.

B. Graves, V. Madison, T. Varnell, 1995, Agents and actions. Supplements.

Beads-on-a-String, Characterization of Ets-1 Sumoylated within Its Flexible N-terminal Sequence*

L. McIntosh, B. Graves, Matthew S Macauley, 2006, Journal of Biological Chemistry.

ETS transcription factors An ERK 2 docking site in the Pointed domain distinguishes a subset of

B. Graves, J. Seidel, J. J. Seidel, 2002 .

autoinhibition Phosphorylation represses Ets-1 DNA binding by reinforcing

B. Graves, D. Cowley, 2000 .

DNA Binding by the ETS Protein TEL (ETV6) Is Regulated by Autoinhibition and Self-association*

L. McIntosh, B. Graves, H. Coyne, 2010, The Journal of Biological Chemistry.

A gene trap approach in mouse embryonic stem cells: the lacZ reported is activated by splicing, reflects endogenous gene expression, and is mutagenic in mice.

W. C. Forrester, S. Higashijima, A. Joyner, 1992, Genes & development.

Synergy of aromatic residues and phosphoserines within the intrinsically disordered DNA-binding inhibitory elements of the Ets-1 transcription factor

L. McIntosh, B. Graves, M. Okon, 2014, Proceedings of the National Academy of Sciences.

Gene deregulation and chronic activation in natural killer cells deficient in the transcription factor ETS1.

M. Sigvardsson, B. Kee, B. Graves, 2012, Immunity.

Steric mechanism of auto-inhibitory regulation of specific and non-specific DNA binding by the ETS transcriptional repressor ETV6.

M. Murphy, L. McIntosh, B. Graves, 2014, Journal of molecular biology.

Expression profiles frame the promoter specificity dilemma of the ETS family of transcription factors.

Peter C. Hollenhorst, David A Jones, B. Graves, 2004, Nucleic acids research.

Autoinhibition of ETV6 (TEL) DNA binding: appended helices sterically block the ETS domain.

B. Graves, Soumya De, M. Okon, 2012, Journal of molecular biology.

Modulation of transcription factor Ets-1 DNA binding: DNA-induced unfolding of an alpha helix.

B. Graves, J. M. Petersen, Lawrence P. McIntosh, 1995, Science.

Dual views of SRF: a genomic exposure

B. Graves, K. Clark, 2014, Genes & development.

Detection and assignment of phosphoserine and phosphothreonine residues by 13C–31P spin-echo difference NMR spectroscopy

L. McIntosh, B. Brutscher, M. L. Nelson, 2009, Journal of biomolecular NMR.