H. Okayama

Kozo Nakamura, Sakae Tanaka, T. Takato, 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Nicotinamide adenine dinucleotide glycohydrolase from rat liver nuclei. Isolation and characterization of a new enzyme.

H. Okayama, O. Hayaishi, K. Ueda, 1975, The Journal of biological chemistry.

High–Level Expression of Human Lipocortin I in the Fission Yeast Schizosaccharomyces pombe Using a Novel Expression Vector

H. Okayama, H. Tohda, H. Okada, 1994, Bio/Technology.

A copy-number-controlled expression vector for the fission yeast Schizosaccharomyces pombe.

H. Okayama, H. Tohda, H. Okada, 1994, Gene.

Detection of genes with a potential for suppressing the transformed phenotype associated with activated ras genes.

H. Kitayama, Y. Ikawa, H. Okayama, 1989, Proceedings of the National Academy of Sciences of the United States of America.

J. Campisi, E. Hara, H. Nojima, 1994, The Journal of biological chemistry.

Isolation of two members of the rat MAP kinase kinase gene family

H. Okayama, Y. Terada, M. Otsu, 1993, FEBS letters.

Chemical DNA damage activates p21WAF1/CIP1‐dependent intra‐S checkpoint

H. Okayama, S. Jinno, Hanako Yamamoto, 2007, FEBS letters.

An RNA Binding Protein Negatively Controlling Differentiation in Fission Yeast

H. Okayama, K. Tsukahara, Hanako Yamamoto, 1998, Molecular and Cellular Biology.

Novel Factor Highly Conserved among Eukaryotes Controls Sexual Development in Fission Yeast

H. Okayama, Yoshinori Watanabe, Masayuki Yamamoto, 1998, Molecular and Cellular Biology.

A zinc finger protein required for stationary phase viability in fission yeast.

H. Okayama, A. Nagata, Hiroto Okayama, 1997, Journal of cell science.

A double-strand break repair component is essential for S phase completion in fission yeast cell cycling.

H. Murakami, H. Okayama, A. Nagata, 1999, Molecular biology of the cell.

Cdk6-cyclin D3 complex evades inhibition by inhibitor proteins and uniquely controls cell's proliferation competence

H. Okayama, Jie Lin, S. Jinno, 2001, Oncogene.

Cell cycle start from quiescence controlled by tyrosine phosphorylation of Cdk4

H. Okayama, S. Jinno, S. Hung, 1999, Oncogene.

NAD glycohydrolases from rat liver nuclei.

H. Okayama, O. Hayaishi, K. Ueda, 1980, Methods in enzymology.

HCV RNA and antibody to HCV core protein in Japanese patients with chronic liver disease

N. Hayashi, A. Kasahara, H. Fusamoto, 1992, Digestive Diseases and Sciences.

Expression of MBP-HCV NS1/E2 fusion protein in E. coli and detection of anti-NS1/E2 antibody in type C chronic liver disease.

N. Hayashi, A. Kasahara, H. Fusamoto, 1992, Biochemical and biophysical research communications.

Novel enzyme from rat liver that cleaves an ADP-ribosyl histone linkage.

M. Honda, H. Okayama, O. Hayaishi, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Purification and properties of poly(adenosine diphosphate ribose) synthetase.

H. Okayama, O. Hayaishi, K. Ueda, 1977, The Journal of biological chemistry.

Cdc6 Protein Activates p27KIP1-bound Cdk2 Protein Only after the Bound p27 Protein Undergoes C-terminal Phosphorylation*

H. Okayama, S. Jinno, Jung-Ha Park, 2012, The Journal of Biological Chemistry.

Analysis of full-length cDNA clones carrying GAL1 of Saccharomyces cerevisiae: a model system for cDNA expression.

K. Arai, H. Okayama, A. Miyajima, 1984, Nucleic acids research.

CrkII signals from epidermal growth factor receptor to Ras.

M. Matsuda, H. Okayama, S. Kizaka-Kondoh, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Mammalian Rcd1 is a novel transcriptional cofactor that mediates retinoic acid‐induced cell differentiation

Takaaki Ito, Noriko Hiroi, Takahiro Ochiya, 2002, The EMBO journal.

A Schizosaccharomyces pombe gene that promotes sexual differentiation encodes a helix‐loop‐helix protein with homology to MyoD.

H. Okayama, B. Benton, M. Reid, 1993, The EMBO journal.

Raf‐1 is not a major upstream regulator of MAP kinases in rat fibroblasts

H. Okayama, S. Kizaka-Kondoh, S. Kizaka‐Kondoh, 1993, FEBS letters.

Calcium phosphate mediated gene transfer into established cell lines.

H. Okayama, C. Chen, 1991, Methods in molecular biology.

Role of TGF-beta in EGF-induced transformation of NRK cells is sustaining high-level EGF-signaling.

H. Okayama, S. Kizaka-Kondoh, N. Akiyama, 2000, FEBS letters.

Structure and organization of the hepatitis C virus genome isolated from human carriers

H. Okayama, S. Manabe, C. Mori, 1991, Journal of virology.

High efficiency transformation of Escherichia coli with plasmids.

H. Nojima, H. Okayama, Hiroto Okayama, 1990, Gene.

Calcium phosphate-mediated gene transfer: a highly efficient transfection system for stably transforming cells with plasmid DNA.

H. Okayama, C. Chen, 1988, BioTechniques.

High-efficiency transformation of mammalian cells by plasmid DNA.

H. Okayama, H Okayama, C Chen, 1987, Molecular and cellular biology.

Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed

H. Blau, L. Kedes, P. Gunning, 1983, Molecular and cellular biology.

[24] Poly(ADP-ribose) synthetase from rat liver nuclei

H. Okayama, O. Hayaishi, K. Ueda, 1980 .

Bovine papillomavirus contains multiple transforming genes.

P. Howley, H. Okayama, Yuh Cheng Yang, 1985, Proceedings of the National Academy of Sciences of the United States of America.

High-efficiency cloning of full-length cDNA

H. Okayama, P. Berg, 1982, Molecular and cellular biology.

A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells.

H. Okayama, P. Berg, 1983, Molecular and cellular biology.

Cloning and sequencing of cDNA of bovine N-acetylglucosamine (beta 1-4)galactosyltransferase.

K. Brew, H. Okayama, H. Narimatsu, 1986, Proceedings of the National Academy of Sciences of the United States of America.

H. Blau, P. Gunning, H. Okayama, 1983, Molecular and cellular biology.

Structure and expression of a human oxytocin receptor

K. Mori, M. Brownstein, H. Okayama, 1992, Nature.

Cdc25A is a novel phosphatase functioning early in the cell cycle.

H Nojima, A Nagata, H. Nojima, 1994, The EMBO journal.

Possible involvement of LKB1-AMPK signaling in non-homologous end joining

J. Yokota, C. Harris, H. Ogiwara, 2014, Oncogene.

Liver fructose-1,6-bisphosphatase cDNA: trans-complementation of fission yeast and characterization of two human transcripts.

H. Okayama, R. Bertolotti, L. Armbruster-Hilbert, 1995, Differentiation; research in biological diversity.

Production of nonstructural proteins of hepatitis C virus requires a putative viral protease encoded by NS3.

H. Okayama, S. Yoshida, Y. Gomi, 1994, Virology.

Cell cycle control in fission yeast and mammals: identification of new regulatory mechanisms.

K. Tanaka, H. Murakami, H. Okayama, 1996, Advances in cancer research.

Calcium Phosphate Transfection

R. Kingston, H. Okayama, Claudia A. Chen, 1999, Current protocols in immunology.

Calcium Phosphate Transfection

R. Kingston, H. Okayama, Claudia A. Chen, 1997, Current protocols in neuroscience.

The G1/S boundary-specific enhancer of the rat cdc2 promoter

T. Nakamura, H. Nojima, H. Okayama, 1995 .

H. Nojima, H. Okayama, T. Nakajima, 1995 .

Isolation and Characterization of a Full-Length Expressible cDNA for Human Hypoxanthine Phosphoribosyltransferase

P. Bohlen, T. Friedmann, H. Okayama, 1983 .

Mammalian target of rapamycin complex 1 signaling opposes the effects of anchorage loss, leading to activation of Cdk4 and Cdc6 stabilization

H. Okayama, S. Jinno, Jung-Ha Park, 2010, FEBS letters.

Bacteriophage lambda vector for transducing a cDNA clone library into mammalian cells

H. Okayama, P. Berg, 1985, Molecular and cellular biology.

Cell cycle checkpoint control

H. Murakami, H. Okayama, Hiroto Okayama, 1997, Experimental & Molecular Medicine.

Functional cDNA expression cloning: Pushing it to the limit

H. Okayama, 2012, Proceedings of the Japan Academy. Series B, Physical and biological sciences.

A WD repeat protein controls the cell cycle and differentiation by negatively regulating Cdc2/B-type cyclin complexes.

H. Murakami, H. Okayama, S. Yamaguchi, 1997, Molecular biology of the cell.

Fission Yeast Cdc24 Is a Replication Factor C- and Proliferating Cell Nuclear Antigen-Interacting Factor Essential for S-Phase Completion

H. Murakami, H. Okayama, Koichi Tanaka, 1999, Molecular and Cellular Biology.

A kinase from fission yeast responsible for blocking mitosis in S phase

H. Murakami, H. Okayama, 1995, Nature.

Establishment and maintenance of sister chromatid cohesion in fission yeast by a unique mechanism

Mihoko Kai, H. Okayama, Koichi Tanaka, 2001, The EMBO journal.

The polyubiquitin gene is essential for meiosis in fission yeast.

O. Niwa, H. Okayama, K. Okazaki, 2000, Experimental cell research.

Fission Yeast Eso1p Is Required for Establishing Sister Chromatid Cohesion during S Phase

M. Yanagida, H. Murakami, Mihoko Kai, 2000, Molecular and Cellular Biology.

A new cdc gene required for S phase entry of Schizosaccharomyces pombe encodes a protein similar to the cdc 10+ and SWI4 gene products.

K. Tanaka, H. Nojima, H. Okayama, 1992, The EMBO journal.

Mammalian Cell Cycle.

H. Okayama, 1993 .

Stress signal, mediated by a Hogl‐like MAP kinase, controls sexual development in fission yeast

H. Murakami, H. Okayama, P. Fantes, 1996, FEBS letters.

Identification of open reading frames in Schizosaccharomyces pombe cDNAs.

H. Nojima, H. Okayama, K. Kato, 1997, DNA research : an international journal for rapid publication of reports on genes and genomes.

Fission yeast Fizzy‐related protein srw1p is a G1‐specific promoter of mitotic cyclin B degradation

P. Nurse, H. Okayama, Satoko Yamaguchi, 2000, The EMBO journal.

Fission yeast Rep2 is a putative transcriptional activator subunit for the cell cycle ‘start’ function of Res2‐Cdc10.

K. Tanaka, H. Okayama, S. Sturm, 1995, The EMBO journal.

res2+, a new member of the cdc10+/SWI4 family, controls the ‘start’ of mitotic and meiotic cycles in fission yeast.

K. Tanaka, H. Okayama, Koichi Tanaka, 1994, EMBO Journal.

A B‐type cyclin negatively regulates conjugation via interacting with cell cycle ‘start’ genes in fission yeast.

H. Okayama, T. Obara-Ishihara, 1994, The EMBO journal.

Human chorionic gonadotropin α and human cytomegalovirus promoters are extremely active in the fission yeast Schizosaccharomyces pombe

R. Toyama, H. Okayama, 1990 .

Human chorionic gonadotropin alpha and human cytomegalovirus promoters are extremely active in the fission yeast Schizosaccharomyces pombe.

R. Toyama, H. Okayama, 1990, FEBS letters.

Requirement for tyrosine phosphorylation of Cdk4 in Gl arrest induced by ultraviolet irradiation

M. Tatsuka, H. Okayama, Y. Terada, 1995, Nature.

An additional homolog of the fission yeast cdc25+ gene occurs in humans and is highly expressed in some cancer cells.

A Nagata, H. Okayama, S. Jinno, 1991, The New biologist.

Functional domains of rep2, a transcriptional activator subunit for Res2-Cdc10, controlling the cell cycle "start".

K. Tanaka, H. Okayama, Y. Yuasa, 1998, Molecular biology of the cell.

Cdc6 Determines Utilization of p21WAF1/CIP1-dependent Damage Checkpoint in S Phase Cells*

H. Okayama, S. Jinno, Kohei Kobayashi, 2008, Journal of Biological Chemistry.

ATP-dependent activation of p21WAF1/CIP1-associated Cdk2 by Cdc6

H. Okayama, S. Jinno, Kohei Kobayashi, 2008, Proceedings of the National Academy of Sciences.

Cdc6 protein obstructs apoptosome assembly and consequent cell death by forming stable complexes with activated Apaf-1 molecules.

H. Okayama, S. Jinno, Jung-Ha Park, 2012, The Journal of Biological Chemistry.

Cdc6: a trifunctional AAA+ ATPase that plays a central role in controlling the G(1)-S transition and cell survival.

H. Okayama, 2012, Journal of biochemistry.

Successive Phosphorylation of p27KIP1 Protein at Serine-10 and C Terminus Crucially Controls Its Potency to Inactivate Cdk2*

H. Okayama, N. Fujita, Shiho Arakawa-Takeuchi, 2012, The Journal of Biological Chemistry.

Cdc6 Protein Obstructs Apoptosome Assembly and Consequent Cell Death by Forming Stable Complexes with Activated Apaf-1 Molecules*

H. Okayama, S. Jinno, Shiho Arakawa-Takeuchi, 2012, The Journal of Biological Chemistry.

Control of p27 CDK Inhibitor Potency by Phosphorylation Successive Phosphorylation of p27 at Serine-10 and C-Terminus Crucially Controls Its Potency to Inactivate Cdk2*

H. Okayama, N. Fujita, Shiho Arakawa-Takeuchi, 2012 .

Apaf-1 Molecules Forming Stable Complexes with Activated Assembly and Consequent Cell Death by Cdc 6 Protein Obstructs Apoptosome Cell

H. Okayama, S. Jinno, Shiho Arakawa-Takeuchi, 2012 .

Successive Phosphorylation of p 27 KIP 1 Protein at Serine-10 and C Terminus Crucially Controls Its Potency to Inactivate Cdk 2 *

H. Okayama, N. Fujita, Shiho Arakawa-Takeuchi, 2012 .

General strategy for understanding intracellular molecular interaction cascades that elicit stimulus-invoked biological processes

H. Okayama, 2016, Proceedings of the Japan Academy. Series B, Physical and biological sciences.

Poly(ADP-ribosy)ation of nuclear proteins. Enzymatic elongation of chemically synthesized ADP-ribose-histone adducts.

M. Kawaichi, H. Okayama, O. Hayaishi, 1979, The Journal of biological chemistry.

Anticancer agent E7070 inhibits amino acid and uracil transport in fission yeast.

T. Watanabe, T. Nagasu, H. Okayama, 2001, Molecular pharmacology.

Identification and characterization of human Wee1B, a new member of the Wee1 family of Cdk‐inhibitory kinases

M. Nakanishi, H. Okayama, N. Watanabe, 2000, Genes to cells : devoted to molecular & cellular mechanisms.

Wee1 +-like gene in human cells

M. Igarashi, H. Okayama, S. Jinno, 1991, Nature.

POLY (ADP-RIBOSE) AND ADP-RIBOSYLATION OF PROTEINS1

M. Kawaichi, H. Okayama, O. Hayaishi, 1979 .

Characterization of the NAD+ glycohydrolase associated with the rat liver nuclear envelope.

H. Okayama, O. Hayaishi, Y. Takahashi, 1976, Journal of biochemistry.

Nicotinamide adenine dinucleotide glycohydrolase from rat liver nuclei. Isolation and characterization of a new enzyme.

H. Okayama, O. Hayaishi, K. Ueda, 1975, Journal of Biological Chemistry.

Role of a signal transduction pathway which controls disassembly of microfilament bundles and suppression of high-molecular-weight tropomyosin expression in oncogenic transformation of NRK cells.

H. Okayama, A. Masuda, K. Utsumi, 1996, Oncogene.

The ste4+ gene, essential for sexual differentiation of Schizosaccharomyces pombe, encodes a protein with a leucine zipper motif.

K. Tanaka, H. Okayama, K. Okazaki, 1991, Nucleic acids research.

Differential expression of three alpha-tubulin genes in Chinese hamster ovary cells

V. Ling, H. Okayama, E. M. Elliott, 1985, Molecular and cellular biology.

Oncogenic signal-induced ability to enter S phase in the absence of anchorage is the mechanism for the growth of transformed NRK cells in soft agar.

H. Nojima, H. Okayama, Y. Terada, 1992, The New biologist.

Oncogenic cell cycle start control.

H. Okayama, J. Lin, S. Jinno, 2001, Mutation research.

Mammalian G2 regulatory genes and their possible involvement in genetic instability in cancer cells.

H. Okayama, S. Jinno, M. Igarashi, 1991, Princess Takamatsu symposia.

12 – High-Efficiency Cloning of Full-Length cDNA; Construction and Screening of cDNA Expression Libraries for Mammalian Cells

K. Arai, M. Brownstein, T. Yokota, 1989 .