K. Ikeda

发表

Role of Human Cds1 (Chk2) Kinase in DNA Damage Checkpoint and Its Regulation by p53*

M. Nakanishi, M. Hirai, K. Tominaga, 1999, The Journal of Biological Chemistry.

A novel ubiquitin‐binding protein ZNF216 functioning in muscle atrophy

K. Ikeda, T. Natsume, A. Hishiya, 2006, The EMBO journal.

SIRT1 is critical regulator of FOXO-mediated transcription in response to oxidative stress.

C. Chen, N. Motoyama, K. Isobe, 2005, International journal of molecular medicine.

Direct interaction of p21 cyclin-dependent kinase inhibitor with the retinoblastoma tumor suppressor protein.

M. Nakanishi, Y. Kaneko, K. Ikeda, 1999, Biochemical and biophysical research communications.

Regulation of G1 cyclin‐dependent kinases in liver regeneration

M. Nakanishi, K. Ikeda, M. Menjo, 1998, Journal of gastroenterology and hepatology.

Critical Role for the 310 Helix Region of p57Kip2 in Cyclin-dependent Kinase 2 Inhibition and Growth Suppression*

Makoto Nakanishi, Kenjiro Kohri, M. Nakanishi, 1998, The Journal of Biological Chemistry.

Recruitment of NBS1 into PML oncogenic domains via interaction with SP100 protein.

K. Naka, N. Motoyama, K. Ikeda, 2002, Biochemical and biophysical research communications.

Osteocytes regulate primary lymphoid organs and fat metabolism.

T. Matsui, K. Ikeda, Mari Sato, 2013, Cell metabolism.

Calcium-sensing receptor in mature osteoclasts, which are bone resorbing cells.

T. Kameda, K. Ikeda, H. Kawashima, 1998, Biochemical and biophysical research communications.

Transforming Growth Factor-β Stimulates the Production of Osteoprotegerin/Osteoclastogenesis Inhibitory Factor by Bone Marrow Stromal Cells*

K. Ikeda, Ken Watanabe, H. Takai, 1998, The Journal of Biological Chemistry.

Osteocytes in Mechanosensing: Insights from Mouse Models and Human Patients

K. Ikeda, Ken Watanabe, 2011 .

Targeted ablation of osteocytes induces osteoporosis with defective mechanotransduction.

Minqi Li, Kenji Kohno, Toshihiro Kobayashi, 2007, Cell metabolism.

K. Ikeda, S. Takeshita, Toshio Fumoto, 2014, The Journal of Biological Chemistry.

Mineralocorticoid receptor function in bone metabolism and its role in glucocorticoid-induced osteopenia.

K. Ikeda, G. Schütz, Masako Ito, 2014, Biochemical and biophysical research communications.

Physiological Functions of Osteoblast Lineage and T Cell–Derived RANKL in Bone Homeostasis

K. Ikeda, S. Takeshita, Masako Ito, 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[Bone metabolism and aging].

K. Ikeda, 2013, Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics.

Matrix-embedded osteocytes regulate mobilization of hematopoietic stem/progenitor cells.

M. Tanimoto, T. Matsui, K. Ikeda, 2013, Cell stem cell.

Osteocytes in the pathogenesis of osteoporosis

K. Ikeda, 2008, Geriatrics & gerontology international.

[Osteoporosis: from pathogenesis to therapy].

K. Ikeda, 2003, Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics.

Alfacalcidol Inhibits Bone Resorption and Stimulates Formation in an Ovariectomized Rat Model of Osteoporosis: Distinct Actions from Estrogen

E. Ogata, Toshitaka Nakamura, K. Ikeda, 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

ED-71, a vitamin D analog, is a more potent inhibitor of bone resorption than alfacalcidol in an estrogen-deficient rat model of osteoporosis.

E. Ogata, K. Ikeda, E. Ogata, 2002, Bone.

Loss of p27(Kip1) accelerates DNA replication after partial hepatectomy in mice.

A. Matsuura, M. Nakanishi, M. Nagino, 2003, The Journal of surgical research.

Cell cycle-dependent phosphorylation of p27 cyclin-dependent kinase (Cdk) inhibitor by cyclin E/Cdk2.

M. Nakanishi, H. Morisaki, A. Fujimoto, 1997, Biochemical and biophysical research communications.

Stress-induced Premature Senescence in hTERT-expressing Ataxia Telangiectasia Fibroblasts*

K. Naka, N. Motoyama, K. Ikeda, 2004, Journal of Biological Chemistry.

Complex mechanisms underlying impaired activation of Cdk4 and Cdk2 in replicative senescence: roles of p16, p21, and cyclin D1.

J. R. Smith, M. Nakanishi, O. Pereira-smith, 1999, Experimental cell research.

Physiological function of the angiotensin AT1a receptor in bone remodeling

A. Fukamizu, K. Ikeda, J. Ishida, 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The role of osteoclast differentiation and function in skeletal homeostasis.

K. Ikeda, S. Takeshita, 2016, Journal of biochemistry.

Association of Transforming Growth Factor β1 Genotype with Therapeutic Response to Active Vitamin D for Postmenopausal Osteoporosis

K. Ikeda, M. Shiraki, T. Hosoi, 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Association of a Polymorphism of the Transforming Growth Factor‐β1 Gene with Genetic Susceptibility to Osteoporosis in Postmenopausal Japanese Women

K. Ikeda, H. Takai, Yoshiji Yamada, 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

1,25‐Dihydroxyvitamin D3 as Well as Its Analogue OCT Lower Blood Calcium Through Inhibition of Bone Resorption in Hypercalcemic Rats with Continuous Parathyroid Hormone–Related Peptide Infusion

Toshitaka Nakamura, K. Ikeda, E. Ogata, 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Immunological Characterization of Circulating Osteoprotegerin/Osteoclastogenesis Inhibitory Factor: Increased Serum Concentrations in Postmenopausal Women with Osteoporosis

K. Ikeda, Y. Yamada, M. Goto, 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Lanthanum carbonate stimulates bone formation in a rat model of renal insufficiency with low bone turnover

K. Ikeda, Masako Ito, Toshio Fumoto, 2014, Journal of Bone and Mineral Metabolism.

Urinary γ-glutamyltransferase (GGT) as a potential marker of bone resorption

Toshihiro Kobayashi, S. Niida, Y. Nimura, 2006 .

A convenient method for the evaluation of anti-tumor agents affecting the cell cycle.

T. Masujima, K. Ikeda, K. Ozawa, 2000, Journal of bioscience and bioengineering.

A Novel Mitochondrial Carnitine-acylcarnitine Translocase Induced by Partial Hepatectomy and Fasting*

H. Aburatani, A. Matsuura, Y. Nimura, 2003, Journal of Biological Chemistry.

NAK is an IkappaB kinase-activating kinase.

M. Karin, M. Nakanishi, Y. Nimura, 2000, Nature.

Ataxia telangiectasia mutated (Atm) knockout mice as a model of osteopenia due to impaired bone formation.

H. Aburatani, N. Motoyama, K. Ikeda, 2005, Bone.

Vitamin D Hormone Inhibits Osteoclastogenesis In Vivo by Decreasing the Pool of Osteoclast Precursors in Bone Marrow

E. Ogata, K. Ikeda, A. Hishiya, 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Modulation of bone remodeling by active vitamin D: its role in the treatment of osteoporosis

E. Ogata, K. Ikeda, 2000, Mechanisms of Ageing and Development.

The effect of vitamin D on osteoblasts and osteoclasts

E. Ogata, K. Ikeda, 1999 .

Proliferation-coupled osteoclast differentiation by RANKL: Cell density as a determinant of osteoclast formation.

A. Miyawaki, Asako Sakaue-Sawano, K. Ikeda, 2015, Bone.

VEGF receptor 1 signaling is essential for osteoclast development and bone marrow formation in colony-stimulating factor 1-deficient mice.

T. Noda, M. Shibuya, S. Niida, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Detection of osteoclastic cell-cell fusion through retroviral vector packaging.

K. Matsuo, K. Ikeda, T. Kondo, 2004, Bone.

Phorbol ester inhibits DNA damage-induced apoptosis in U937 cells through activation of protein kinase C.

M. Nakanishi, Y. Kaneko, K. Ikeda, 1999, Life sciences.

A RANKL-Inducible Gene Znf216 in Osteoclast Differentiation

K. Ikeda, A. Hishiya, Ken Watanabe, 2005, Journal of receptor and signal transduction research.

WAIF1 Is a Cell‐Surface CTHRC1 Binding Protein Coupling Bone Resorption and Formation

K. Ikeda, S. Takeshita, Masako Ito, 2018, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Secretion of PDGF isoforms during osteoclastogenesis and its modulation by anti-osteoclast drugs.

K. Ikeda, S. Takeshita, M. M. Rahman, 2015, Biochemical and biophysical research communications.

Factors and Mechanisms Involved in the Coupling from Bone Resorption to Formation: How Osteoclasts Talk to Osteoblasts

K. Ikeda, S. Takeshita, 2014, Journal of bone metabolism.

SIRT1 Regulates Thyroid-Stimulating Hormone Release by Enhancing PIP5Kγ Activity through Deacetylation of Specific Lysine Residues in Mammals

L. Guarente, Y. Eishi, Si-young Song, 2010, PloS one.

SIRT1 Regulates Thyroid-Stimulating Hormone Release by Enhancing PIP5K[subscript gamma] Activity through Deacetylation of Specific Lysine Residues in Mammals

L. Guarente, Y. Eishi, Si-young Song, 2010 .

γ-Glutamyltranspeptidase Stimulates Receptor Activator of Nuclear Factor-κB Ligand Expression Independent of Its Enzymatic Activity and Serves as a Pathological Bone-resorbing Factor*

S. Niida, Y. Ikeda, N. Taniguchi, 2004, Journal of Biological Chemistry.

Interaction Between Nitric Oxide Synthase and Cyclooxygenase Pathways in Osteoblastic MC3T3‐E1 Cells

Yoshiji Yamada, K. Ikeda, Yoshiji Yamada, 1997, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Coordination of PGC-1β and iron uptake in mitochondrial biogenesis and osteoclast activation

H. Aburatani, C. Lelliott, K. Ikeda, 2009, Nature Medicine.

Filamin Associates with Smads and Regulates Transforming Growth Factor-β Signaling*

K. Ikeda, Ken Watanabe, A. Sasaki, 2001, The Journal of Biological Chemistry.

NAK is an IκB kinase-activating kinase

M. Karin, M. Nakanishi, Y. Nimura, 2000, Nature.

Cyclin E as a Coactivator of the Androgen Receptor

S. Kato, E. Ogata, M. Nakanishi, 2000, The Journal of cell biology.

Chk2‐deficient mice exhibit radioresistance and defective p53‐mediated transcription

E. Appella, Hiroshi Suzuki, M. Nakanishi, 2002, The EMBO journal.

ALKR1275Q perturbs extracellular matrix, enhances cell invasion and leads to the development of neuroblastoma in cooperation with MYCN

K. Tanaka, N. Onishi, H. Saya, 2016, Oncogene.

Osteocytes in Normal Physiology and Osteoporosis

K. Ikeda, Ken Watanabe, 2010 .

Abnormal Angiogenesis in Foxo1 (Fkhr)-deficient Mice*

S. Nishikawa, K. Nakayama, T. Furuyama, 2004, Journal of Biological Chemistry.

Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice.

Y. A. Minamishima, K. Nakayama, M. Nakanishi, 2000, Genes & development.

Osteoclast-secreted CTHRC1 in the coupling of bone resorption to formation.

H. Aburatani, S. Kato, K. Ikeda, 2013, The Journal of clinical investigation.

Critical role for p27Kip1 in cell cycle arrest after androgen depletion in mouse mammary carcinoma cells (SC-3)

E. Ogata, M. Nakanishi, Y. Kaneko, 1998, Oncogene.

FOXO Forkhead Transcription Factors Induce G2-M Checkpoint in Response to Oxidative Stress*

N. Motoyama, K. Ikeda, Yoko Furukawa-Hibi, 2002, The Journal of Biological Chemistry.

Potent Prostaglandin A1 Analogs That Suppress Tumor Cell Growth through Induction of p21 and Reduction of Cyclin E*

M. Nakanishi, K. Tominaga, H. Morisaki, 1998, The Journal of Biological Chemistry.

Hydrocephalus, Situs Inversus, Chronic Sinusitis, and Male Infertility in DNA Polymerase λ-Deficient Mice: Possible Implication for the Pathogenesis of Immotile Cilia Syndrome

Hiroshi Suzuki, M. Nakanishi, N. Motoyama, 2002, Molecular and Cellular Biology.

Increased osteocyte death and mineralization inside bone after parathyroidectomy in patients with secondary hyperparathyroidism

Masaaki Inaba, Yoshihiro Tominaga, K. Ikeda, 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Osteoclast‐Derived Complement Component 3a Stimulates Osteoblast Differentiation

K. Ikeda, S. Takeshita, Masako Ito, 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Cell cycle-dependent and ATM-independent expression of human Chk1 kinase

M. Nakanishi, K. Tominaga, H. Morisaki, 1999, Oncogene.

Prostaglandin E2 Induces Expression of Receptor Activator of Nuclear Factor–κB Ligand/Osteoprotegrin Ligand on Pre‐B Cells: Implications for Accelerated Osteoclastogenesis in Estrogen Deficiency

K. Ikeda, Ken Watanabe, H. Takai, 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

A RING Finger Protein Praja1 Regulates Dlx5-dependent Transcription through Its Ubiquitin Ligase Activity for the Dlx/Msx-interacting MAGE/Necdin Family Protein, Dlxin-1*

K. Ikeda, Ken Watanabe, A. Sasaki, 2002, The Journal of Biological Chemistry.

Role of Inducible Nitric Oxide Synthase in Skeletal Adaptation to Acute Increases in Mechanical Loading

Toshitaka Nakamura, K. Ikeda, Ken Watanabe, 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Dlxin-1, a Novel Protein That Binds Dlx5 and Regulates Its Transcriptional Function*

H. Shibuya, N. Ueno, K. Ikeda, 2001, The Journal of Biological Chemistry.

Integrin αv in the mechanical response of osteoblast lineage cells.

K. Ikeda, A. Lacy-Hulbert, Masako Ito, 2014, Biochemical and biophysical research communications.

Efficient Transfer of Genes into Senescent Cells by Adenovirus Vectors via Highly Expressed αvβ5 Integrin

M. Nakanishi, K. Ikeda, K. Kohri, 1997 .

[Osteoblast differentiation and bone formation].

K. Ikeda, Ken Watanabe, 2009, Nihon rinsho. Japanese journal of clinical medicine.

c-Fos protein as a target of anti-osteoclastogenic action of vitamin D, and synthesis of new analogs.

E. Ogata, K. Ikeda, A. Sugita, 2006, The Journal of clinical investigation.

Identification and Characterization of Human DNA Polymerase β2, a DNA Polymerase β-Related Enzyme*

M. Nakanishi, Y. Nimura, M. Hirai, 2000, The Journal of Biological Chemistry.

Induction of KAI-1 expression in metastatic cancer cells by phorbol esters.

A. Iizuka, M. Nakanishi, K. Ikeda, 2000, Cancer letters.

Metabolic regulation of osteoclast differentiation and function

H. Aburatani, A. Hirao, K. Ikeda, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Generation of Bone‐Resorbing Osteoclasts from B220+ Cells: Its Role in Accelerated Osteoclastogenesis due to Estrogen Deficiency *

K. Ikeda, K. Watanabe, K. Ikeda, 2001, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Vitamin D, osteoclastogenesis and bone resorption: from mechanistic insight to the development of new analogs.

K. Ikeda, 2007, Endocrine journal.

Multi‐Detector Row CT Imaging of Vertebral Microstructure for Evaluation of Fracture Risk

Hajime Orimo, Masataka Uetani, Hiroyuki Shindo, 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Effects of a prostaglandin EP4 agonist, ONO-4819, and risedronate on trabecular microstructure and bone strength in mature ovariectomized rats.

K. Ikeda, A. Konaka, T. Maruyama, 2006, Bone.

Serum CTX levels and histomorphometric analysis in Src versus RANKL knockout mice

K. Ikeda, S. Takeshita, Masako Ito, 2018, Journal of Bone and Mineral Metabolism.

Life-long caloric restriction reveals biphasic and dimorphic effects on bone metabolism in rodents.

Masako Ito, K. Ikeda, Masako Ito, 2008, Endocrinology.

Overexpression of gamma-glutamyltransferase in transgenic mice accelerates bone resorption and causes osteoporosis.

Sakae Tanaka, S. Niida, Y. Nimura, 2007, Endocrinology.

[Mitochondrial function in bone resorption and formation].

K. Ikeda, 2011, Nihon rinsho. Japanese journal of clinical medicine.

Regulation of G1 cyclin-dependent kinases in liver regeneration.

M. Nakanishi, K. Ikeda, M. Menjo, 1998, Journal of Gastroenterology and Hepatology.