J. Bernal

B. Seliger, S. Llanos, T. Iglesias, 1994, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Type 3 iodothyronine deiodinase is selectively expressed in areas related to sexual differentiation in the newborn rat brain.

J. Bernal, A. Cuadrado, A. Guadaño-Ferraz, 1999, Endocrinology.

Thyroid hormone regulators in human cerebral cortex development.

J. Bernal, Diego Diez, B. Morte, 2022, The Journal of endocrinology.

High sensitivity of a rat liver nucleoplasmic protein to triiodothyronine

J. Bernal, A. Rodríguez-Peña, J. Bernal, 1982, FEBS letters.

Generalized deficiency of 3,5,3'-triiodo-L-thyronine (T3) in tissues from rats on a low iodine intake, despite normal circulating T3 levels.

J. Bernal, M. Obregon, F. Escobar del Rey, 1989, Acta endocrinologica.

Thyroid hormone regulation of rhes, a novel Ras homolog gene expressed in the striatum.

P. Vargiu, J. Bernal, J. Gregor Sutcliffe, 2001, Brain research. Molecular brain research.

Lack of thyroid hormone receptor α1 is associated with selective alterations in behavior and hippocampal circuits

J. DeFelipe, R. Benavides-Piccione, C. Sandi, 2003, Molecular Psychiatry.

In vivo activity of the thyroid hormone receptor beta- and α-selective agonists GC-24 and CO23 on rat liver, heart, and brain.

J. Bernal, T. Scanlan, É. Samarut, 2011, Endocrinology.

Differential effects of triiodothyronine and the thyroid hormone receptor beta-specific agonist GC-1 on thyroid hormone target genes in the b ain.

J. Bernal, T. Scanlan, B. Morte, 2003, Endocrinology.

Perspectives in the study of thyroid hormone action on brain development and function.

J. Bernal, A. Guadaño-Ferraz, B. Morte, 2003, Thyroid : official journal of the American Thyroid Association.

Thyroid hormone and the development of the brain

J. Bernal, A. Guadaño-Ferraz, 1998 .

Independent expression of the alpha and beta c-erbA genes in developing rat brain.

J. Bernal, B. Mellström, J. Naranjo, 1991, Molecular endocrinology.

Ontogenesis of thyroid hormone receptor in foetal lambs.

J. Bernal, B. Potter, B. Ferreiro, 1987, Acta endocrinologica.

Faculty Opinions recommendation of Neuronal 3',3,5-triiodothyronine (T3) uptake and behavioral phenotype of mice deficient in Mct8, the neuronal T3 transporter mutated in Allan-Herndon-Dudley syndrome.

J. Bernal, 2009 .

Effect of Triiodothyroacetic Acid Treatment in Mct8 Deficiency: A Word of Caution.

J. Bernal, M. Obregon, A. Guadaño-Ferraz, 2016, Thyroid : official journal of the American Thyroid Association.

Effect of the exposure to cold on the extrathyroidal conversion of L-thyroxine to triiodo-L-thyronine, and on intramitochondrial alpha-glycerophosphate dehydrogenase activity in thyroidectomized rats on L-thyroxine.

J. Bernal, F. D. del Rey, 1975, Acta endocrinologica.

Inhibition by propylthiouracil of the extrathyroidal formation of triiodothyronine from thyroxine.

J. Bernal, F. Escobar del Rey, 1974, Acta endocrinologica.

Thyroid hormone action in the adult brain: gene expression profiling of the effects of single and multiple doses of triiodo-L-thyronine in the rat striatum.

A. Pinchera, J. Bernal, G. D. de Escobar, 2008, Endocrinology.

RC3/neurogranin is expressed in pyramidal neurons of motor and somatosensory cortex in normal and denervated monkeys

J. Bernal, E. Rausell, A. Guadaño-Ferraz, 2005, The Journal of comparative neurology.

The Human RC3 Gene Homolog, NRGN Contains a Thyroid Hormone-Responsive Element Located in the First Intron* * This work was supported by grants from Fundación Ramon Areces and DGICYT (PM95-0019).

J. Bernal, A. Coloma, B. Morte, 1999, Endocrinology.

The human RC3 gene homolog, NRGN contains a thyroid hormone-responsive element located in the first intron.

J. Bernal, A. Coloma, B. Morte, 1999, Endocrinology.

Structure, organization, and chromosomal mapping of the human neurogranin gene (NRGN).

J. Bernal, L. P. Pérez Jurado, A. Coloma, 1997, Genomics.

Thyroid hormones and brain development.

J. Bernal, J. Nunez, 1995, European journal of endocrinology.

Thyroid hormone receptor/c-erbA: control of commitment and differentiation in the neuronal/chromaffin progenitor line PC12

B. Seliger, J. Bernal, A. Muñoz, 1993, The Journal of cell biology.

Adult rat brain is sensitive to thyroid hormone. Regulation of RC3/neurogranin mRNA.

J. Bernal, N. Ibarrola, G. Morreale de Escobar, 1992, The Journal of clinical investigation.

Cell-specific effects of thyroid hormone on RC3/neurogranin expression in rat brain.

J. Sutcliffe, L. Lecea, J. Bernal, 1996, Endocrinology.

Characterization of the promoter region and flanking sequences of the neuron-specific gene RC3 (neurogranin).

J. Sutcliffe, J. Bernal, A. Muñoz, 1994, Brain research. Molecular brain research.

Thyroid hormone regulation of RC3, a brain-specific gene encoding a protein kinase-C substrate.

J. Bernal, A. Muñoz, N. Ibarrola, 1993, Endocrinology.

Action of thyroid hormone in brain

J. Bernal, 2002, Journal of endocrinological investigation.

Iodine and brain development

J. Bernal, 1999, BioFactors.

5.08 – Thyroid Hormones and Brain Development

J. Bernal, 2017 .

74 – Thyroid Hormones and Brain Development

J. Bernal, 2002 .

Thyroid Hormone Regulates reelin and dab1Expression During Brain Development

M. Álvarez-Dolado, J. D. del Río, T. Curran, 1999, The Journal of Neuroscience.

Occurrence of Cucurbit Yellow Stunting Disorder Virus (CYSDV) and Beet Pseudo-yellows Virus in Cucurbit Crops in Spain and Transmission of CYSDV by Two Biotypes of Bemisia tabaci

J. Bernal, F. Beitia, E. Sáez, 1999, European Journal of Plant Pathology.

Rhes Is Involved in Striatal Function

P. Mithbaokar, E. Alleva, A. Affuso, 2004, Molecular and Cellular Biology.

Deletion of the thyroid hormone receptor α1 prevents the structural alterations of the cerebellum induced by hypothyroidism

J. Bernal, T. Scanlan, B. Vennström, 2002, Proceedings of the National Academy of Sciences of the United States of America.

The type 2 iodothyronine deiodinase is expressed primarily in glial cells in the neonatal rat brain.

J. Bernal, M. Obregon, A. Guadaño-Ferraz, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Thyroid Development and Effect on the Nervous System

J. Bernal, P. Santisteban, 2005, Reviews in Endocrine and Metabolic Disorders.

Thyroid hormone regulates stromelysin expression, protease secretion and the morphogenetic potential of normal polarized mammary epithelial cells.

T. Iglesias, J. Bernal, A. Muñoz, 1995, The EMBO journal.

Modulation of adult hippocampal neurogenesis by thyroid hormones: implications in depressive-like behavior

J. García-Verdugo, J. Bernal, C. Venero, 2006, Molecular Psychiatry.

Identification of a thyroid hormone response element in the promoter region of the rat lipocalin-type prostaglandin D synthase (beta-trace) gene.

Y. Urade, J. Bernal, A. Muñoz, 1998, Brain research. Molecular brain research.

Regulation of the L1 Cell Adhesion Molecule by Thyroid Hormone in the Developing Brain

M. Álvarez-Dolado, P. Sonderegger, J. Bernal, 2000, Molecular and Cellular Neuroscience.

Prenatal treatment of thyroid hormone cell membrane transport defect caused by MCT8 gene mutation.

J. Bernal, K. Hansen, R. Weiss, 2020, Thyroid : official journal of the American Thyroid Association.

Placenta passage of the thyroid hormone analog DITPA to male wild-type and Mct8-deficient mice.

J. Bernal, R. Weiss, S. Refetoff, 2014, Endocrinology.

Nucleotide sequence and infectious transcripts from a full-length cDNA clone of the carmovirus Melon necrotic spot virus

J. Bernal, M. Aranda, E. Moriones, 2003, Archives of Virology.

Brain gene expression in systemic hypothyroidism and mouse models of MCT8 deficiency: The Mct8-Oatp1c1-Dio2 triad.

J. Bernal, H. Heuer, B. Morte, 2020, Thyroid.

Thyroid Hormones in Brain Development and Function

J. Bernal, 2015 .

Patterns of cerebral cortex mRNA expression

J. Sutcliffe, J. Bernal, K. Hasel, 1990, Journal of neuroscience research.

Thyroid hormones and brain development.

J. Bernal, 1995, Vitamins and hormones.

Changes in thyroid status during perinatal development of MCT8-deficient male mice.

J. Bernal, R. Weiss, S. Refetoff, 2013, Endocrinology.

Isolation of genomic DNA fragments corresponding to genes modulated in vivo by a transcription factor.

T. Iglesias, J. Caubín, Á. Zaballos, 1994, Nucleic acids research.

Neonatal hypothyroidism affects the timely expression of myelin-associated glycoprotein in the rat brain.

J. Bernal, A. Muñoz, N. Ibarrola, 1993, The Journal of clinical investigation.

Identification of the mammalian homolog of the splicing regulator Suppressor-of-white-apricot as a thyroid hormone regulated gene.

J. Bernal, A. Muñoz, A. Cuadrado, 1999, Brain research. Molecular brain research.

Involvement of thyrotropin-releasing hormone receptor, somatostatin receptor subtype 2 and corticotropin-releasing hormone receptor type 1 in the control of chicken thyrotropin secretion

V. Darras, J. Bernal, E. Kühn, 2003, Molecular and Cellular Endocrinology.

Identification of Novel GH-regulated Genes in C2C12 Cells

J. Bernal, A. Zorzano, I. Illa, 2011, Hormone and Metabolic Research.

Thyroid hormone regulated genes in cerebral cortex development.

J. Bernal, 2017, The Journal of endocrinology.

Global Transcriptome Analysis of Primary Cerebrocortical Cells: Identification of Genes Regulated by Triiodothyronine in Specific Cell Types

J. Dopazo, F. García-García, J. Bernal, 2015, Cerebral cortex.

Regulation of Gene Expression by Thyroid Hormone in Primary Astrocytes: Factors Influencing the Genomic Response

J. Bernal, B. Morte, Pilar Gil-Ibáñez, 2018, Endocrinology.

Transcriptional induction of RC3/neurogranin by thyroid hormone: differential neuronal sensitivity is not correlated with thyroid hormone receptor distribution in the brain.

P. Vargiu, J. Bernal, A. Guadaño-Ferraz, 1997, Brain research. Molecular brain research.

63 – Thyroid Hormones and Brain Development

J. Bernal, 2009 .

Thyroid hormone availability in the human fetal brain: novel entry pathways and role of radial glia

T. Visser, J. Bernal, A. Guadaño-Ferraz, 2019, Brain Structure and Function.

Expression of Type 2 Iodothyronine Deiodinase in Hypothyroid Rat Brain Indicates an Important Role of Thyroid Hormone in the Development of Specific Primary Sensory Systems

J. Bernal, E. Rausell, A. Guadaño-Ferraz, 1999, The Journal of Neuroscience.

Type 3 Iodothyronine Deiodinase Is Selectively Expressed in Areas Related to Sexual Differentiation in the Newborn Rat Brain.

J. Bernal, A. Cuadrado, Mari A Jose Esca Mez, 1999, Endocrinology.

Influence of thyroid hormones on maturation of rat cerebellar astrocytes

J. Bernal, B. Morte, J. Manzano, 2007, International Journal of Developmental Neuroscience.

Effects of neonatal hypothyroidism on rat brain gene expression.

J. Sutcliffe, J. Bernal, A. Muñoz, 1991, Molecular endocrinology.

Anxiety, memory impairment, and locomotor dysfunction caused by a mutant thyroid hormone receptor alpha1 can be ameliorated by T3 treatment.

J. Bernal, C. Venero, G. D. de Escobar, 2005, Genes & development.

Thyroid hormone receptor activity in the absence of ligand: physiological and developmental implications.

J. Bernal, B. Morte, 2013, Biochimica et biophysica acta.

The small GTP-binding protein, Rhes, regulates signal transduction from G protein-coupled receptors

A. Valencia, P. Vargiu, P. Crespo, 2004, Oncogene.

Biological activities of thyroid hormone receptors.

J. Bernal, A. Muñoz, 1997, European journal of endocrinology.

Late maternal hypothyroidism alters the expression of Camk4 in neocortical subplate neurons: a comparison with Nurr1 labeling.

J. Bernal, P. Berbel, D. Navarro, 2014, Cerebral cortex.

Retinoic acid posttranscriptionally up-regulates proteolipid protein gene expression in C6 glioma cells.

H. Stunnenberg, T. Iglesias, J. Bernal, 1993, The Journal of biological chemistry.

Generation and Characterization of dickkopf3 Mutant Mice

H. Fuchs, D. Busch, E. Wolf, 2006, Molecular and Cellular Biology.

Alien/CSN2 gene expression is regulated by thyroid hormone in rat brain.

J. Bernal, A. Muñoz, S. Tenbaum, 2003, Developmental biology.

Thyroid Hormone Economy in the Perinatal Mouse Brain: Implications for Cerebral Cortex Development

J. Bernal, M. Obregon, A. Guadaño-Ferraz, 2018, Cerebral cortex.

Identification of a cis‐acting element that interferes with thyroid hormone induction of the neurogranin (NRGN) gene

J. Bernal, A. Coloma, B. Morte, 1999, FEBS letters.

Thyroid hormone regulation of gene expression in the developing rat fetal cerebral cortex: prominent role of the Ca2+/calmodulin-dependent protein kinase IV pathway.

J. Bernal, P. Berbel, G. D. de Escobar, 2010, Endocrinology.

T3 receptor occupancy and T3 levels in plasma and cytosol during rat brain development.

J. Bernal, B. Ferreiro, R. Pastor, 1990, Acta endocrinologica.

Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism.

P. Kopp, J. Bernal, G. Brent, 2014, The Journal of clinical endocrinology and metabolism.

Classification and Proposed Nomenclature for Inherited Defects of Thyroid Hormone Action, Cell Transport, and Metabolism

P. Kopp, J. Bernal, G. Brent, 2014, European Thyroid Journal.

Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism.

P. Kopp, J. Bernal, G. Brent, 2014, Thyroid : official journal of the American Thyroid Association.

Thyroid Hormone-Dependent Regulation of Tα1 α-Tubulin during Brain Development

F. Miller, J. Bernal, P. I. Lorenzo, 2002, Molecular and Cellular Neuroscience.

Single-cell transcriptome profiling of thyroid hormone effectors in the human fetal neocortex: expression of SLCO1C1, DIO2, and THRB in specific cell types.

J. Bernal, Diego Diez, B. Morte, 2021, Thyroid : official journal of the American Thyroid Association.

Aberrant maturation of astrocytes in thyroid hormone receptor alpha 1 knockout mice reveals an interplay between thyroid hormone receptor isoforms.

J. Bernal, T. Scanlan, B. Vennström, 2004, Endocrinology.

Chronic in vivo Ipamorelin treatment stimulates body weight gain and growth hormone (GH) release in vitro in young famale rats.

J. Bernal, M. D. L. Torre, L. Jiménez-Reina, 2002 .

Thyroid hormone dependent nuclear proteins from rat liver.

J. Bernal, A. Rodríguez-Peña, 1982, Acta endocrinologica.

The significance of thyroid hormone transporters in the brain.

J. Bernal, 2005, Endocrinology.

Nuclear binding of triiodothyronine in human mononuclear cells, and lymphocytes in culture.

J. Bernal, S. Saukkonen-Bernal, 1983, Acta endocrinologica. Supplementum.

Divergent expression of type 2 deiodinase and the putative thyroxine-binding protein p29, in rat brain, suggests that they are functionally unrelated proteins.

J. Bernal, A. Guadaño-Ferraz, A. Montero-Pedrazuela, 2003, Endocrinology.

The nuclear 3,5,3'-triiodothyronine receptor in human leukaemic cell lines.

L. Andersson, J. Bernal, 1984, Acta endocrinologica.

Editorial: “Thyroid Hormone in Brain and Brain Cells”

N. Koibuchi, J. Bernal, F. Flamant, 2015, Front. Endocrinol..

Concomitant decrease of the effects of thyroxin on TRH-induced TSH release, and of the pituitary content of triiodothyronine in animals on propylthiouracil.

J. Bernal, F. Escobar del Rey, G. Morreale de Escobar,, 1974, Endocrinology.

Role of monocarboxylate anion transporter 8 (MCT8) in thyroid hormone transport: Answers from mice.

J. Bernal, 2006, Endocrinology.

Thyroid hormone signaling is highly heterogeneous during pre- and postnatal brain development.

J. Bernal, J. Samarut, A. Guadaño-Ferraz, 2004, Journal of molecular endocrinology.

Brain-specific prostaglandin D2 synthetase mRNA is dependent on thyroid hormone during rat brain development.

J. Bernal, A. Muñoz, L. García-Fernández, 1993, Biochemical and biophysical research communications.

T3/T4 Ratios and α-Glycerophosphate Activity in Intact Rats Exposed to a Cold Environment

J. Bernal, F. E. D. Rey, 1975 .

Induction of platelet-derived growth factor B/c-sis by the v-erbA oncogene in glial cells.

B. Seliger, S. Llanos, T. Iglesias, 1995, Oncogene.

Unliganded c-erbA/thyroid hormone receptor induces trkB expression in neuroblastoma cells.

J. Bernal, A. Rodríguez-Peña, R. Pastor, 1994, Oncogene.

Is the Intrinsic Genomic Activity of Thyroxine Relevant In Vivo? Effects on Gene Expression in Primary Cerebrocortical and Neuroblastoma Cells.

J. Bernal, M. Obregon, Mónica M. Belinchón, 2017, Thyroid : official journal of the American Thyroid Association.

Expression Analysis of Genes Regulated by Thyroid Hormone in Neural Cells.

J. Bernal, B. Morte, 2018, Methods in molecular biology.

TITLE: Modulation of adult hippocampal neurogenesis by thyroid hormones: implications in depressive-like behavior Authors: Montero-Pedrazuela

J. Bernal, A. Guadaño-Ferraz, A. Montero-Pedrazuela, 2005 .