J. Schwabe

发表

The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: How receptors discriminate between their response elements

John W. R. Schwabe, Lynda Chapman, Daniela Rhodes, 1993, Cell.

Structural basis for the activation of PPARgamma by oxidized fatty acids.

J. Schwabe, T. Itoh, L. Fairall, 2008, Nature structural & molecular biology.

Transient expression in HEK 293 cells: an alternative to E. coli for the production of secreted and intracellular mammalian proteins.

R. Owens, J. Schwabe, L. Fairall, 2015, Methods in molecular biology.

Zinc fingers

A Klug, A. Klug, J. Schwabe, 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Targeting Class I Histone Deacetylases in a "Complex" Environment.

J. Schwabe, L. Fairall, P. Watson, 2017, Trends in pharmacological sciences.

Structure of HDAC3 bound to corepressor and inositol tetraphosphate

J. Schwabe, L. Fairall, P. Watson, 2011, Nature.

Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates

C. Robinson, S. Cowley, I. Celardo, 2013, Molecular cell.

Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension

S. O’Rahilly, I. Barroso, J. Schwabe, 1999, Nature.

The crystal structure of a two zinc-finger peptide reveals an extension to the rules for zinc-finger/DNA recognition

John W. R. Schwabe, Louise Fairall, Lynda Chapman, 1993, Nature.

The role of water in protein-DNA interactions.

J. Schwabe, J W Schwabe, John W. R. Schwabe, 1997, Current opinion in structural biology.

St John's wort, a herbal antidepressant, activates the steroid X receptor.

J. Schwabe, V. Chatterjee, J. Love, 2000, The Journal of endocrinology.

Insights into the Recruitment of Class IIa Histone Deacetylases (HDACs) to the SMRT/NCoR Transcriptional Repression Complex*

J. Schwabe, L. Fairall, P. Watson, 2015, The Journal of Biological Chemistry.

Histone deacetylase 3 indirectly modulates tubulin acetylation

R. Grigg, J. Schwabe, P. Watson, 2015, The Biochemical journal.

Towards an understanding of the structure and function of MTA1

J. Schwabe, L. Fairall, C. J. Millard, 2014, Cancer and Metastasis Reviews.

A mutation in the thyroid hormone receptor alpha gene.

K. Downes, F. Vargha-Khadem, F. Muntoni, 2012, The New England journal of medicine.

Optimization of Class I Histone Deacetylase PROTACs Reveals that HDAC1/2 Degradation is Critical to Induce Apoptosis and Cell Arrest in Cancer Cells

S. Cowley, J. Schwabe, K. Bowman, 2022, Journal of medicinal chemistry.

Nuclear Receptors: The Evolution of Diversity

S. Teichmann, J. Schwabe, 2004, Science's STKE.

A Proteomic Profile of Cervical Remodeling in Mice during Early and Late Pregnancy

J. Schwabe, P. Leppert, S. Jesmin, 2014 .

Complex behaviour

J. Schwabe, D. Rhodes, 1991, Nature.

Selective Aster inhibitors distinguish vesicular and nonvesicular sterol transport mechanisms

J. Schwabe, D. Ory, P. Tontonoz, 2020, Proceedings of the National Academy of Sciences.

A Pharmacogenetic Approach to the Treatment of Patients With PPARG Mutations

S. O’Rahilly, A. Majithia, J. Schwabe, 2018, Diabetes.

Maternal isodisomy for chromosome 9 causing homozygosity for a novel FOXE1 mutation in syndromic congenital hypothyroidism.

U. Mallya, F. Raymond, J. Schwabe, 2010, The Journal of clinical endocrinology and metabolism.

Structural Basis for the Activation of Pparg by Oxidised Fatty Acids

J. Schwabe, T. Itoh, L. Fairall, 2008 .

Structure-Guided Approach to Relieving Transcriptional Repression in Resistance to Thyroid Hormone α

J. Schwabe, L. Fairall, L. Persani, 2021, Molecular and cellular biology.

Diverse nucleosome Site-Selectivity among histone deacetylase complexes

P. Cole, Zhipeng A. Wang, J. Schwabe, 2020, eLife.

FERM-dependent E3 ligase recognition is a conserved mechanism for targeted degradation of lipoprotein receptors

J. Schwabe, L. Fairall, P. Tontonoz, 2011, Proceedings of the National Academy of Sciences.

Engineered PQQ-Dependent Alcohol Dehydrogenase for the Oxidation of 5-(Hydroxymethyl)furoic Acid

N. Wierckx, J. Schwabe, M. Wehrmann, 2020 .

Spurring on transcription?

A. Travers, J. Schwabe, John R. Schwabe, 1993, Current Biology.

Residual activity of mutant androgen receptors explains wolffian duct development in the complete androgen insensitivity syndrome.

J. Schwabe, I. Hughes, N. Coleman, 2004, The Journal of clinical endocrinology and metabolism.

Outgrowth and patterning of the vertebrate limb.

J. Schwabe, C. Rodríguez-Esteban, J. Izpisúa-Belmonte, 1997, Cold Spring Harbor symposia on quantitative biology.

An unexpected histone chaperone function for the MIER1 histone deacetylase complex

M. Collins, J. Schwabe, L. Fairall, 2022, bioRxiv.

PROTAC-mediated degradation of class I histone deacetylase enzymes in corepressor complexes.

S. Cowley, J. Schwabe, C. J. Millard, 2020, Chemical Communications.

Discussion of the Paper

G. Clore, K. Sakaguchi, E. Appella, 1994 .

Structural and biochemical insights into heterotetramer formation between human oncogenic K-Ras4BG12V and Rgl2, a RalA/B activator

J. Schwabe, L. Fairall, A. J. Hudson, 2022, bioRxiv.

deacetylase 3 indirectly modulates tubulin acetylation.

R. Grigg, J. Schwabe, M. Peckham, 2015 .

Mutations in TBL1X Are Associated With Central Hypothyroidism

W. Dreschler, R. Hennekam, E. Fliers, 2016, The Journal of clinical endocrinology and metabolism.

The cocrystal structures of two zinc-stabilized DNA-binding domains illustrate different ways of achieving sequence-specific DNA recognition.

J. Finch, J. Schwabe, L. Chapman, 1993, Cold Spring Harbor Symposia on Quantitative Biology.

Edinburgh Research Explorer Non-DNA binding, dominant-negative, human PPARgamma mutations cause lipodystrophic insulin resistance

S. O’Rahilly, N. Wareham, I. Barroso, 2018 .

Three Novel Mutations at Serine 314 in the Thyroid Hormone β Receptor Differentially Impair Ligand Binding in the Syndrome of Resistance to Thyroid Hormone1.

A. Pinchera, J. Schwabe, M. Gurnell, 1999, Endocrinology.

Transcriptional repression by nuclear receptors: mechanisms and role in disease.

J. Schwabe, L. Nagy, V. Chatterjee, 2000, Biochemical Society transactions.

Sexual precocity and recurrent beta-human chorionic gonadotropin upsurges preceding the diagnosis of a malignant mediastinal germ-cell tumor in a 9-year-old boy.

J. Schwabe, U. Göbel, B. Hauffa, 2002, Annals of oncology : official journal of the European Society for Medical Oncology.

Hydroxamic Acid-Modified Peptide Library Provides Insights into the Molecular Basis for the Substrate Selectivity of HDAC Corepressor Complexes

J. Schwabe, N. Robertson, P. Watson, 2022, ACS chemical biology.

The oestrogen receptor recognizes an imperfectly palindromic response element through an alternative side-chain conformation.

J. Schwabe, L. Chapman, D. Rhodes, 1995, Structure.

International Union of Pharmacology. LXVI. Orphan Nuclear Receptors

Vincent Laudet, Jean-Paul Renaud, A. Cooney, 2006, Pharmacological Reviews.

Identification of a Novel Co-regulator Interaction Surface on the Ligand Binding Domain of Nurr1 Using NMR Footprinting*

J. Schwabe, T. Perlmann, G. Benoit, 2004, Journal of Biological Chemistry.

Synthesis of HDAC Substrate Peptidomimetic Inhibitors Using Fmoc Amino Acids Incorporating Zinc-Binding Groups

J. Schwabe, C. J. Millard, Amit Mahindra, 2019, Organic letters.

Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans.

F. Muntoni, N. Wareham, M. Dattani, 2010, The Journal of clinical investigation.

Immature teratoma arising from an intra-abdominal testis in a 5-month-old boy.

C. Gerharz, J. Schwabe, D. Schneider, 2000, Medical and pediatric oncology.

Genetic disorders of nuclear receptors

J. Schwabe, L. Fairall, J. Achermann, 2017, The Journal of clinical investigation.

A Death Effector Domain Chain DISC Model Reveals a Crucial Role for Caspase-8 Chain Assembly in Mediating Apoptotic Cell Death

Louise Fairall, J. Schwabe, L. Fairall, 2012, Molecular cell.

Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex

P. Cole, J. Schwabe, N. Robertson, 2020, Cell reports.

Assembly and Regulation of Nuclear Receptor Corepressor Complexes

J. Schwabe, C. J. Millard, 2015 .

An evolving understanding of nuclear receptor coregulator proteins.

Louise Fairall, J. Schwabe, L. Fairall, 2013, Journal of molecular endocrinology.

Radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limb

Concepción Rodríguez-Esteban, J. Schwabe, J. Peña, 1997, Nature.

A specific mutation in TBL1XR1 causes Pierpont syndrome

Francesca Forzano, G Bradley Schaefer, Aldo Jongejan, 2016, Journal of Medical Genetics.

The structure of the core NuRD repression complex provides insights into its interaction with chromatin

Kyle L. Morris, J. Schwabe, L. Fairall, 2016, eLife.

Negative regulation by nuclear receptors: a plethora of mechanisms

J. Schwabe, L. Fairall, Guilherme M. Santos, 2011, Trends in Endocrinology & Metabolism.

A de novo substitution in BCL11B leads to loss of interaction with transcriptional complexes and craniosynostosis

S. Twigg, P. J. van der Spek, J. Schwabe, 2019, Human molecular genetics.

Lhx2, a vertebrate homologue of apterous, regulates vertebrate limb outgrowth.

J. I. Izpisúa Belmonte, J. Botas, Concepción Rodríguez-Esteban, 1998, Development.

Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery

J. Schwabe, L. Fairall, L. Nagy, 2011, Nature Structural &Molecular Biology.

Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors

Yun Song, Mingxuan Wu, Jeffrey J Gray, 2018, Nature Communications.

Non-DNA binding, dominant-negative, human PPARγ mutations cause lipodystrophic insulin resistance

S. O’Rahilly, N. Wareham, I. Barroso, 2006, Cell metabolism.

Tyrosine agonists reverse the molecular defects associated with dominant-negative mutations in human peroxisome proliferator-activated receptor gamma.

T. Willson, S. O’Rahilly, H. Xu, 2004, Endocrinology.

A Dominant-negative Peroxisome Proliferator-activated Receptor γ (PPARγ) Mutant Is a Constitutive Repressor and Inhibits PPARγ-mediated Adipogenesis*

M. Lazar, J. Schwabe, M. Gurnell, 2000, The Journal of Biological Chemistry.

A dominant negative human peroxisome proliferator-activated receptor (PPAR){alpha} is a constitutive transcriptional corepressor and inhibits signaling through all PPAR isoforms.

V K K Chatterjee, S. O’Rahilly, A. Meirhaeghe, 2005, Endocrinology.

Molecular Determinants of the Balance between Co-repressor and Co-activator Recruitment to the Retinoic Acid Receptor*

J. Schwabe, L. Nagy, S. Benkő, 2003, Journal of Biological Chemistry.

A dynamic mechanism of nuclear receptor activation and its perturbation in a human disease

J. Schwabe, V. Chatterjee, J. Love, 2003, Nature Structural Biology.

The Structural Basis for the Specificity of Retinoid-X Receptor-selective Agonists: New Insights Into the Role of Helix H12*

R. Evans, J. Schwabe, L. Nagy, 2002, The Journal of Biological Chemistry.

Histone deacetylase (HDAC) 1 and 2 are essential for accurate cell division and the pluripotency of embryonic stem cells

O. Dovey, S. Cowley, J. Schwabe, 2014, Proceedings of the National Academy of Sciences.

STAT6 Transcription Factor Is a Facilitator of the Nuclear Receptor PPARγ-Regulated Gene Expression in Macrophages and Dendritic Cells

R. Evans, E. Barta, Y. Barak, 2010, Immunity.

Beyond zinc fingers: steroid hormone receptors have a novel structural motif for DNA recognition.

J. Schwabe, D. Rhodes, 1991, Trends in biochemical sciences.

The steroid/nuclear receptors: from three-dimensional structure to complex function.

B. Luisi, L. Freedman, J. Schwabe, 1994, Vitamins and hormones.

Nuclear hormone receptor co-repressors: Structure and function

J. Schwabe, L. Fairall, P. Watson, 2012, Molecular and Cellular Endocrinology.

What is evolution playing at?

A. Travers, J. Schwabe, 1993, Current Biology.

Structural and biochemical insights into heterotetramer formation of oncogenic K-Ras4BG12V and Rgl2, a RalA/B activator

J. Schwabe, L. Fairall, A. J. Hudson, 2022, bioRxiv.

DNA recognition by the oestrogen receptor: from solution to the crystal.

D Neuhaus, J W Schwabe, L Chapman, 1993, Structure.

The Ansamycin Antibiotic, Rifamycin SV, Inhibits BCL6 Transcriptional Repression and Forms a Complex with the BCL6-BTB/POZ Domain

P. Ko Ferrigno, J. Schwabe, L. Fairall, 2014, PloS one.

A dominant-negative peroxisome proliferator-activated receptor gamma (PPARgamma) mutant is a constitutive repressor and inhibits PPARgamma-mediated adipogenesis.

M. Lazar, J. Schwabe, M. Gurnell, 2000, The Journal of biological chemistry.

Backbone resonance assignment of the BCL6-BTB/POZ domain

J. Schwabe, F. Muskett, L. Fairall, 2017, Biomolecular NMR Assignments.

Galactose metabolism in Zea mays root tissues observed by 31P-NMR spectroscopy

J. Schwabe, R. Ratcliffe, B. Loughman, 1989 .

Zinc mining for protein domains

A. Klug, J. Schwabe, 1994, Nature Structural Biology.

In vitro evolution predicts emerging SARS-CoV-2 mutations with high affinity for ACE2 and cross-species binding

J. Ball, J. Sale, J. Schwabe, 2021, bioRxiv.

The topology of chromatin-binding domains in the NuRD deacetylase complex

J. Schwabe, L. Fairall, T. J. Ragan, 2020, Nucleic acids research.

A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes

N. Brockdorff, J. Schwabe, R. Fischer, 2018, Nature Communications.

Limbs are moving: where are they going?

J. I. Izpisúa Belmonte, J. Schwabe, C. Rodríguez-Esteban, 1998, Trends in genetics : TIG.

Histone H2B Deacylation Selectivity: Exploring Chromatin’s Dark Matter with an Engineered Sortase

Yingming Zhao, Zhipeng A. Wang, J. Schwabe, 2022, Journal of the American Chemical Society.

The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure

Kyle L. Morris, A. Roseman, S. Cowley, 2020, Nature Communications.

Lysine-14 acetylation of histone H3 in chromatin confers resistance to the deacetylase and demethylase activities of an epigenetic silencing complex

P. Cole, J. Schwabe, Yun Song, 2018, eLife.

Disruption of the Class IIa HDAC Corepressor Complex Increases Energy Expenditure and Lipid Oxidation.

M. Febbraio, Min Wu, J. Schwabe, 2016, Cell reports.

Insights into the activation mechanism of class I HDAC complexes by inositol phosphates

A. M. Riley, S. Cowley, J. Schwabe, 2016, Nature Communications.

Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting

J. Schwabe, F. Muskett, T. Itoh, 2015, Nucleic acids research.

Towards an understanding of protein-DNA recognition.

J. Schwabe, L. Chapman, D. Rhodes, 1996, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Mzt1/Tam4, a fission yeast MOZART1 homologue, is an essential component of the γ-tubulin complex and directly interacts with GCP3Alp6

Crispin J. Miller, Danny A. Bitton, J. Schwabe, 2013, Molecular biology of the cell.

Solution structure of the DNA-binding domain of the oestrogen receptor.

J. Schwabe, D. Rhodes, D. Neuhaus, 1990, Nature.

Comparison of the molecular consequences of different mutations at residue 754 and 690 of the androgen receptor (AR) and androgen insensitivity syndrome (AIS) phenotype

J. Schwabe, I. Hughes, T. Bunch, 2009, Clinical endocrinology.

Solution structures of two zinc-finger domains from SWI5 obtained using two-dimensional 1H nuclear magnetic resonance spectroscopy. A zinc-finger structure with a third strand of beta-sheet.

A Klug, D Neuhaus, Y Nakaseko, 1992, Journal of molecular biology.

Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate

D. Dinsdale, J. Schwabe, L. Fairall, 2021, Nature Communications.

Co-operative and Hierarchical Binding of c-FLIP and Caspase-8: A Unified Model Defines How c-FLIP Isoforms Differentially Control Cell Fate

J. Schwabe, L. Fairall, M. Leverkus, 2016, Molecular cell.

Co-operative and Hierarch ical Binding of c-FLIP and Caspase-8 : A Unified Model Defines How c-FLIP Isoforms Differentially Control Cell Fate Graphical

J. Schwabe, L. Fairall, M. Leverkus, 2016 .

Structural insights into the interaction and activation of histone deacetylase 3 by nuclear receptor corepressors

M. Lazar, J. Schwabe, D. Neuhaus, 2005, Proceedings of the National Academy of Sciences of the United States of America.

HDAC3 deacetylates the DNA mismatch repair factor MutSβ to stimulate triplet repeat expansions

J. Schwabe, F. Muskett, Janice Ortega, 2020, Proceedings of the National Academy of Sciences.

The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor.

J. Schwabe, L. Fairall, P. Tontonoz, 2011, Genes & development.

A novel CYP11B2 gene mutation in an Asian family with aldosterone synthase deficiency.

J. Schwabe, V. Chatterjee, R. Bernhardt, 2006, The Journal of clinical endocrinology and metabolism.

Channels at the catalytic site of glycogen phosphorylase b: binding and kinetic studies with the beta-glycosidase inhibitor D-gluconohydroximo-1,5-lactone N-phenylurethane.

J. Hajdu, L. Johnson, D. Barford, 1988, Biochemistry.

Mechanism of the nuclear receptor molecular switch.

J. Schwabe, L. Nagy, 2004, Trends in biochemical sciences.

Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells

E. Ikonen, S. Young, J. Schwabe, 2018, Cell.

Contrasting Phenotypes in Resistance to Thyroid Hormone Alpha Correlate with Divergent Properties of Thyroid Hormone Receptor α1 Mutant Proteins

A. Offiah, J. Schwabe, S. Price, 2016, Thyroid : official journal of the American Thyroid Association.

Structural insights into the complex of oncogenic K-Ras4BG12V and Rgl2, a RalA/B activator

J. Schwabe, L. Fairall, A. J. Hudson, 2023, bioRxiv.

Histone deacetylase (HDAC) 1 and 2 complexes regulate both histone acetylation and crotonylation in vivo

M. Blades, S. Cowley, J. Schwabe, 2018, Scientific Reports.

Recombinant Protein Expression for Structural Biology in HEK 293F Suspension Cells: A Novel and Accessible Approach

S. Cowley, J. Schwabe, L. Fairall, 2014, Journal of visualized experiments : JoVE.

Structural basis for the activation of PPARγ by oxidized fatty acids

J. Schwabe, T. Itoh, L. Fairall, 2008, Nature Structural &Molecular Biology.

Signal transduction: Fast lane to transcriptional activation

J. Schwabe, D. Rhodes, 1998, Current Biology.

Human androgen receptor gene ligand-binding-domain mutations leading to disrupted interaction between the N- and C-terminal domains.

N. Mongan, J. Schwabe, I. Hughes, 2006, Journal of molecular endocrinology.

NOXA, a sensor of proteasome integrity, is degraded by 26S proteasomes by an ubiquitin-independent pathway that is blocked by MCL-1

G M Cohen, A Craxton, M Butterworth, 2012, Cell Death and Differentiation.

Heme binding to human CLOCK affects interactions with the E-box

Samuel L. Freeman, C. Kyriacou, J. Schwabe, 2019, Proceedings of the National Academy of Sciences.

Linkers made to measure

J. Schwabe, D. Rhodes, 1997, Nature Structural Biology.

Two de novo mutations in the AR gene cause the complete androgen insensitivity syndrome in a pair of monozygotic twins.

M. Dattani, N. Mongan, J. Schwabe, 2002, The Journal of clinical endocrinology and metabolism.

A conserved structural motif reveals the essential transcriptional repression function of Spen proteins and their role in developmental signaling.

Mariko Ariyoshi, J. Schwabe, M. Ariyoshi, 2003, Genes & development.

Expression and Purification of Protein Complexes Suitable for Structural Studies Using Mammalian HEK 293F Cells

J. Schwabe, L. Fairall, Irene Nigi, 2017, Current protocols in protein science.

A Novel Albumin Gene Mutation (R222I) in Familial Dysalbuminemic Hyperthyroxinemia

J. Schwabe, M. Gurnell, P. Beck‐Peccoz, 2014, The Journal of clinical endocrinology and metabolism.

A potential histone-chaperone activity for the MIER1 histone deacetylase complex

M. Collins, J. Schwabe, T. K. Pham, 2023, Nucleic acids research.

Towards an understanding of the structure and function of MTA1

J. Schwabe, L. Fairall, C. J. Millard, 2014, Cancer Metastasis Review.

A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes

N. Brockdorff, J. Schwabe, R. Fischer, 2018, Nature Communications.

BIM-Mediated Membrane Insertion of the BAK Pore Domain Is an Essential Requirement for Apoptosis

G. Cohen, J. Schwabe, N. Harper, 2013, Cell reports.

Erratum: Radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limb

Concepción Rodriguez-Esteban, John W. R. Schwabe, Jennifer De La Peña, 1997, Nature.

Aster-dependent non-vesicular transport facilitates dietary cholesterol uptake

Julia J. Mack, S. Young, J. Schwabe, 2023, bioRxiv.

Mechanism of corepressor binding and release from nuclear hormone receptors.

R. Evans, R. Evans, J. Schwabe, 1999, Genes & development.

Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors

Jeffrey J. Gray, Shourya S. Roy Burman, J. Jeliazkov, 2018, Nature Communications.

The phantom ligand effect: allosteric control of transcription by the retinoid X receptor.

R. Evans, R. Evans, J. Schwabe, 1997, Genes & development.

Mutations in TBL1X Are Associated With Central Hypothyroidism

W. Dreschler, R. Hennekam, E. Fliers, 2016, The Journal of clinical endocrinology and metabolism.

Direct G Protein Modulation of Cav2 Calcium Channels

B. Spiegelman, S. Kliewer, G. Eichele, 2006, Pharmacological Reviews.

Structural insights into the complex of oncogenic KRas4BG12V and Rgl2, a RalA/B activator

J. Schwabe, L. Fairall, A. J. Hudson, 2023, bioRxiv.

DNA between the sheets

J. Schwabe, 1992, Current Biology.

An evolving understanding of nuclear receptor coregulator proteins.

J. Schwabe, L. Fairall, P. Watson, 2013, Journal of Molecular Endocrinology.

International Union of Pharmacology. LXVI. Orphan Nuclear Receptors

A. Cooney, F. Sladek, V. Giguère, 2006, Pharmacological Reviews.

Structural insights into the complex of oncogenic KRas4BG12V and Rgl2, a RalA/B activator

J. Schwabe, L. Fairall, A. J. Hudson, 2023, bioRxiv.

Solution structure of the DNA-binding domain of the oestrogen receptor.

J. Schwabe, D. Rhodes, D. Neuhaus, 1990, Nature.

The structure of the core NuRD repression complex provides insights into its interaction with chromatin

J. Schwabe, L. Fairall, A. Bottrill, 2016, eLife.

A de novo substitution in BCL11B leads to loss of interaction with transcriptional complexes and craniosynostosis

S. Twigg, P. J. van der Spek, J. Schwabe, 2019, Human molecular genetics.