Koon-Guan Lee

发表

BTK blocks the inhibitory effects of MDM2 on p53 activity

N. Barlev, S. Macip, M. Althubiti, 2017, Oncotarget.

Bruton's tyrosine kinase phosphorylates Toll-like receptor 3 to initiate antiviral response

S. Akira, O. Takeuchi, Koon-Guan Lee, 2012, Proceedings of the National Academy of Sciences.

Phospholipase Cγ2 Is Critical for Dectin-1-mediated Ca2+ Flux and Cytokine Production in Dendritic Cells*

Koon-Guan Lee, K. Lam, T. Kurosaki, 2009, Journal of Biological Chemistry.

Bruton's Tyrosine Kinase Separately Regulates NFκB p65RelA Activation and Cytokine Interleukin (IL)-10/IL-12 Production in TLR9-stimulated B Cells*

E. Wong, Koon-Guan Lee, K. Lam, 2008, Journal of Biological Chemistry.

arrest B-cell development at a pre-BCR+ stage 2 γ Combined deficiencies in Bruton tyrosine kinase and phospholipase C

Koon-Guan Lee, K. Lam, T. Kurosaki, 2013 .

Combined deficiencies in Bruton tyrosine kinase and phospholipase Cgamma2 arrest B-cell development at a pre-BCR+ stage.

Koon-Guan Lee, K. Lam, T. Kurosaki, 2007, Blood.

DOK3 Is Required for IFN-β Production by Enabling TRAF3/TBK1 Complex Formation and IRF3 Activation

Koon-Guan Lee, K. Lam, S. Ng, 2014, The Journal of Immunology.

BTK Modulates p53 Activity to Enhance Apoptotic and Senescent Responses.

N. Barlev, S. Macip, M. Althubiti, 2016, Cancer research.

Combined deﬁciencies in Bruton tyrosine kinase and phospholipase C (cid:1) 2 arrest B-cell development at a pre-BCR (cid:2) stage

Koon-Guan Lee, K. Lam, T. Kurosaki, 2007 .

Bruton's tyrosine kinase phosphorylates DDX41 and activates its binding of dsDNA and STING to initiate type 1 interferon response.

B. Sukumaran, L. Rénia, D. Voon, 2015, Cell reports.

DOK3 maintains intestinal homeostasis by suppressing JAK2/STAT3 signaling and S100a8/9 production in neutrophils

Koon-Guan Lee, K. Lam, Alison P Lee, 2021, Cell Death & Disease.

Bruton's Tyrosine Kinase and Protein Kinase C µ Are Required for TLR7/9-Induced IKKα and IRF-1 Activation and Interferon-β Production in Conventional Dendritic Cells

Koon-Guan Lee, K. Lam, Xijun Ou, 2014, PloS one.

BTK: sensing pathogenic nucleic acids

Koon-Guan Lee, K. Lam, 2015, Oncotarget.

And Irf3 Activation Enabling Traf3/tbk1 Complex Formation Production by Β Dok3 Is Required for Ifn- Dok3 Is Required for Ifn-b Production by Enabling Traf3/tbk1 Complex Formation and Irf3 Activation Coimmunoprecipitations and Immunoblotting Immunofluorescence and Confocal Microscopy Quantitative Rt-

Koon-Guan Lee, K. Lam, Shengli Xu, 2022 .

Bruton's tyrosine kinase phosphorylates DDX41 and activates its binding of dsDNA and STING to initiate type 1 interferon response.

B. Sukumaran, L. Rénia, D. Voon, 2015, Cell reports.

Bruton's tyrosine kinase phosphorylates Toll-like receptor 3 to initiate antiviral response

S. Akira, O. Takeuchi, Koon-Guan Lee, 2012, Proceedings of the National Academy of Sciences.