S. Iezzi

发表

HIPK2 sustains apoptotic response by phosphorylating Che-1/AATF and promoting its degradation

M. Crescenzi, S. Soddu, C. Passananti, 2014, Cell Death and Disease.

Che-1 activates XIAP expression in response to DNA damage

C. Leonetti, M. Scarsella, C. Passananti, 2008, Cell Death and Differentiation.

Stage-specific modulation of skeletal myogenesis by inhibitors of nuclear deacetylases

S. Iezzi, G. Cossu, C. Nervi, 2002, Proceedings of the National Academy of Sciences of the United States of America.

CK2-mediated phosphorylation of Che-1/AATF is required for its pro-proliferative activity

G. Damonte, V. Catena, T. Bruno, 2021, Journal of experimental & clinical cancer research : CR.

Class I histone deacetylases sequentially interact with MyoD and pRb during skeletal myogenesis.

L. Kedes, P. Stiegler, A. Giordano, 2001, Molecular cell.

Che-1 sustains autophagy and multiple myeloma cells growth by inhibiting mTOR pathway in response to cellular stress

G. Blandino, T. Castrignanò, C. Passananti, 2022 .

Che‐1 is targeted by c‐Myc to sustain proliferation in pre‐B‐cell acute lymphoblastic leukemia

G. Blandino, C. Passananti, F. De Nicola, 2018, EMBO reports.

NRAGE associates with the anti-apoptotic factor Che-1 and regulates its degradation to induce cell death

M. Ciotti, N. Corbi, C. Passananti, 2007, Journal of Cell Science.

Functional interaction of the subunit 3 of RNA polymerase II (RPB3) with transcription factor‐4 (ATF4)

N. Corbi, C. Passananti, T. Bruno, 2003, FEBS letters.

Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state.

Po Zhao, E. Hoffman, S. Iezzi, 2003, Molecular cell.

Che-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 Proteins

T. Bruno, S. Iezzi, M. Fanciulli, 2016, Front. Oncol..

Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53

T. Benzing, G. Blandino, C. Passananti, 2015, Cell Death and Disease.

Discovering Che-1/AATF: a new attractive target for cancer therapy

S. Iezzi, M. Fanciulli, 2015, Front. Genet..

Centrosomal Che-1 Protein Is Involved in the Regulation of Mitosis and DNA Damage Response by Mediating Pericentrin (PCNT)-dependent Chk1 Protein Localization*

E. Cundari, C. Passananti, L. Chessa, 2013, The Journal of Biological Chemistry.

Che-1 promotes tumor cell survival by sustaining mutant p53 transcription and inhibiting DNA damage response activation.

Barbara Benassi, Alfonso Bellacosa, Francesca De Nicola, 2010, Cancer cell.

The α‐like RNA polymerase II core subunit 3 (RPB3) is involved in tissue‐specific transcription and muscle differentiation via interaction with the myogenic factor myogenin

N. Corbi, C. Passananti, T. Bruno, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Identification of a novel partner of RNA polymerase II subunit 11, Che‐1, which interacts with and affects the growth suppression function of Rb

C. Passananti, T. Bruno, S. Iezzi, 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Che‐1‐induced inhibition of mTOR pathway enables stress‐induced autophagy

G. Tonon, G. Blandino, T. Castrignanò, 2015, The EMBO journal.

Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint.

C. Leonetti, M. Scarsella, K. Khanna, 2006, Cancer cell.

The Prolyl Isomerase Pin1 Affects Che-1 Stability in Response to Apoptotic DNA Damage*

G. Del Sal, C. Passananti, T. Bruno, 2007, Journal of Biological Chemistry.

HERP, a Novel Heterodimer Partner of HES/E(spl) in Notch Signaling

L. Kedes, S. Iezzi, Hung-Yi Wu, 2001, Molecular and Cellular Biology.

Che-1 Arrests Human Colon Carcinoma Cell Proliferation by Displacing HDAC1 from the p21WAF1/CIP1 Promoter*

Annamaria Biroccio, Francesca De Nicola, Maurizio Fanciulli, 2003, Journal of Biological Chemistry.

Che-1/AATF-induced transcriptionally active chromatin promotes cell proliferation in multiple myeloma.

G. Cigliana, T. Benzing, L. Baldini, 2020, Blood advances.

Deacetylase inhibitors increase muscle cell size by promoting myoblast recruitment and fusion through induction of follistatin.

Eric P Hoffman, Po Zhao, E. Hoffman, 2004, Developmental cell.

Slug Is a Novel Downstream Target of MyoD

Eric P Hoffman, Po Zhao, Thomas Gridley, 2002, The Journal of Biological Chemistry.

Che-1/AATF binds to RNA polymerase I machinery and sustains ribosomal RNA gene transcription

G. Bossi, M. Mano, V. Catena, 2020, Nucleic acids research.

Che-1 sustains hypoxic response of colorectal cancer cells by affecting Hif-1α stabilization

G. Blandino, M. Valerio, C. Manetti, 2017, Journal of Experimental & Clinical Cancer Research.

Che-1 sustains hypoxic response of colorectal cancer cells by affecting Hif-1α stabilization

G. Blandino, M. Valerio, C. Manetti, 2017, Journal of experimental & clinical cancer research : CR.

AATF/Che-1 RNA polymerase II binding protein overexpression reduces the anti-tumor NK-cell cytotoxicity through activating receptors modulation

N. Tumino, G. Piaggio, S. Iezzi, 2023, Frontiers in Immunology.

Deptor transcriptionally regulates endoplasmic reticulum homeostasis in multiple myeloma cells

G. Cigliana, G. Blandino, V. Catena, 2016, Oncotarget.